Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	Q	D	E	Y	Y	M	A	R	A	L	K	L	A	Q	R	G	R	F	T	T	H	P	N	P	N	V	G	C	V	I	V	K	D	G	E	I	V	G	E	G	Y	H	Q	R	A	G	E	P	H	A	E	V	H	A	L	R	M	A	G
Secondary structure
SS confidence
Disorder		?	?																?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		E	K	A	K	G	A	T	A	Y	V	T	L	E	P	C	S	H	H	G	R	T	P	P	C	C	D	A	L	I	A	A	G	V	A	R	V	V	A	S	M	Q	D	P	N	P	Q	V	A	G	R	G	L	Y	R	L	Q	Q	A	G	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		D	V	S	H	G	L	M	M	S	E	A	E	Q	L	N	K	G	F	L	K	R	M	R	T	G	F	P	Y	I	Q	L	K	L	G	A	S	L	D	G	R	T	A	M	A	S	G	E	S	Q	W	I	T	S	P	Q	A	R	R	D	V
Secondary structure
SS confidence
Disorder																																															?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Q	L	L	R	A	Q	S	H	A	I	L	T	S	S	A	T	V	L	A	D	D	P	A	L	T	V	R	W	S	E	L	D	E	Q	T	Q	A	L	Y	P	Q	Q	N	L	R	Q	P	I	R	I	V	I	D	S	Q	N	R	V	T	P
Secondary structure
SS confidence
Disorder																																?	?	?	?			?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		V	H	R	I	V	Q	Q	P	G	E	T	W	F	A	R	T	Q	E	D	S	R	E	W	P	E	T	V	R	T	L	L	I	P	E	H	K	G	H	L	D	L	V	V	L	M	M	Q	L	G	K	Q	Q	I	N	S	I	W	V	E	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		G	P	T	L	A	G	A	L	L	Q	A	G	L	V	D	E	L	I	V	Y	I	A	P	K	L	L	G	S	D	A	R	G	L	C	T	L	P	G	L	E	K	L	A	D	A	P	Q	F	K	F	K	E	I	R	H	V	G	P	D	V
Secondary structure
SS confidence
Disorder																																				?		?	?	?		?	?
Disorder confidence
		.	.	.	.	.	.	.
Sequence		C	L	H	L	V	G	A
Secondary structure
SS confidence
Disorder							?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2d5n chain B Region: 3 - 366 Aligned: 352 Modelled: 352 Confidence: 100.0% Identity: 42% PDB header:hydrolase, oxidoreductase Chain: B: PDB Molecule:riboflavin biosynthesis protein ribd; PDBTitle: crystal structure of a bifunctional deaminase and reductase2 involved in riboflavin biosynthesis Phyre2 PDB 2o7p chain A Region: 2 - 367 Aligned: 352 Modelled: 366 Confidence: 100.0% Identity: 97% PDB header:hydrolase, oxidoreductase Chain: A: PDB Molecule:riboflavin biosynthesis protein ribd; PDBTitle: the crystal structure of ribd from escherichia coli in complex with2 the oxidised nadp+ cofactor in the active site of the reductase3 domain Phyre2 PDB 2hxv chain A Region: 3 - 366 Aligned: 340 Modelled: 348 Confidence: 100.0% Identity: 34% PDB header:biosynthetic protein Chain: A: PDB Molecule:diaminohydroxyphosphoribosylaminopyrimidine deaminase/ 5- PDBTitle: crystal structure of a diaminohydroxyphosphoribosylaminopyrimidine2 deaminase/ 5-amino-6-(5-phosphoribosylamino)uracil reductase (tm1828)3 from thermotoga maritima at 1.80 a resolution Phyre2 PDB 2b3z chain A domain 1 Region: 147 - 366 Aligned: 208 Modelled: 220 Confidence: 100.0% Identity: 32% Fold: Dihydrofolate reductase-like Superfamily: Dihydrofolate reductase-like Family: RibD C-terminal domain-like Phyre2 PDB 2azn chain A domain 1 Region: 144 - 366 Aligned: 210 Modelled: 211 Confidence: 100.0% Identity: 32% Fold: Dihydrofolate reductase-like Superfamily: Dihydrofolate reductase-like Family: RibD C-terminal domain-like Phyre2 PDB 2p4g chain A Region: 132 - 364 Aligned: 228 Modelled: 233 Confidence: 100.0% Identity: 16% PDB header:oxidoreductase Chain: A: PDB Molecule:hypothetical protein; PDBTitle: crystal structure of a pyrimidine reductase-like protein (dip1392)2 from corynebacterium diphtheriae nctc at 2.30 a resolution Phyre2 PDB 2b3z chain A domain 2 Region: 3 - 145 Aligned: 143 Modelled: 143 Confidence: 100.0% Identity: 57% Fold: Cytidine deaminase-like Superfamily: Cytidine deaminase-like Family: Deoxycytidylate deaminase-like Phyre2 PDB 2hxv chain A domain 1 Region: 147 - 366 Aligned: 197 Modelled: 217 Confidence: 100.0% Identity: 26% Fold: Dihydrofolate reductase-like Superfamily: Dihydrofolate reductase-like Family: RibD C-terminal domain-like Phyre2 PDB 2hxv chain A domain 2 Region: 2 - 146 Aligned: 144 Modelled: 144 Confidence: 100.0% Identity: 44% Fold: Cytidine deaminase-like Superfamily: Cytidine deaminase-like Family: Deoxycytidylate deaminase-like Phyre2 PDB 1z3a chain A domain 1 Region: 1 - 146 Aligned: 138 Modelled: 146 Confidence: 100.0% Identity: 33% Fold: Cytidine deaminase-like Superfamily: Cytidine deaminase-like Family: Deoxycytidylate deaminase-like Phyre2 PDB 3ocq chain A Region: 1 - 140 Aligned: 132 Modelled: 140 Confidence: 100.0% Identity: 33% PDB header:hydrolase Chain: A: PDB Molecule:putative cytosine/adenosine deaminase; PDBTitle: crystal structure of trna-specific adenosine deaminase from salmonella2 enterica Phyre2 PDB 2nx8 chain A Region: 2 - 147 Aligned: 138 Modelled: 146 Confidence: 100.0% Identity: 28% PDB header:hydrolase Chain: A: PDB Molecule:trna-specific adenosine deaminase; PDBTitle: the crystal structure of the trna-specific adenosine deaminase from2 streptococcus pyogenes Phyre2 PDB 2b3j chain A domain 1 Region: 2 - 145 Aligned: 136 Modelled: 144 Confidence: 100.0% Identity: 30% Fold: Cytidine deaminase-like Superfamily: Cytidine deaminase-like Family: Deoxycytidylate deaminase-like Phyre2 PDB 2g84 chain A domain 1 Region: 2 - 141 Aligned: 132 Modelled: 133 Confidence: 100.0% Identity: 25% Fold: Cytidine deaminase-like Superfamily: Cytidine deaminase-like Family: Deoxycytidylate deaminase-like Phyre2 PDB 3kgy chain A Region: 142 - 366 Aligned: 210 Modelled: 225 Confidence: 100.0% Identity: 14% PDB header:oxidoreductase Chain: A: PDB Molecule:bifunctional deaminase-reductase domain protein; PDBTitle: crystal structure of putative dihydrofolate reductase (yp_001636057.1)2 from chloroflexus aurantiacus j-10-fl at 1.50 a resolution Phyre2 PDB 1wwr chain A domain 1 Region: 1 - 145 Aligned: 136 Modelled: 139 Confidence: 100.0% Identity: 30% Fold: Cytidine deaminase-like Superfamily: Cytidine deaminase-like Family: Deoxycytidylate deaminase-like Phyre2 PDB 1p6o chain A Region: 3 - 144 Aligned: 130 Modelled: 136 Confidence: 100.0% Identity: 28% Fold: Cytidine deaminase-like Superfamily: Cytidine deaminase-like Family: Deoxycytidylate deaminase-like Phyre2 PDB 3jtw chain B Region: 149 - 366 Aligned: 164 Modelled: 170 Confidence: 100.0% Identity: 18% PDB header:oxidoreductase Chain: B: PDB Molecule:dihydrofolate reductase; PDBTitle: crystal structure of putative dihydrofolate reductase (yp_805003.1)2 from pediococcus pentosaceus atcc 25745 at 1.90 a resolution Phyre2 PDB 3dh1 chain D Region: 2 - 141 Aligned: 132 Modelled: 140 Confidence: 100.0% Identity: 29% PDB header:hydrolase Chain: D: PDB Molecule:trna-specific adenosine deaminase 2; PDBTitle: crystal structure of human trna-specific adenosine-34 deaminase2 subunit adat2 Phyre2 PDB 2gd9 chain A Region: 143 - 364 Aligned: 170 Modelled: 177 Confidence: 100.0% Identity: 19% PDB header:oxidoreductase Chain: A: PDB Molecule:hypothetical protein yyap; PDBTitle: crystal structure of a putative dihydrofolate reductase (bsu40760,2 yyap) from bacillus subtilis at 2.30 a resolution Phyre2 1 c2d5nB_ 2 c2o7pA_ 3 c2hxvA_ 4 d2b3za1 5 d2azna1 6 c2p4gA_ 7 d2b3za2 8 d2hxva1 9 d2hxva2 10 d1z3aa1 11 c3ocqA_ 12 c2nx8A_ 13 d2b3ja1 14 d2g84a1 15 c3kgyA_ 16 d1wwra1 17 d1p6oa_ 18 c3jtwB_ 19 c3dh1D_ 20 c2gd9A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2d5nB_ 100.0 42 PDB header:hydrolase, oxidoreductase Chain: B: PDB Molecule:riboflavin biosynthesis protein ribd; PDBTitle: crystal structure of a bifunctional deaminase and reductase2 involved in riboflavin biosynthesis 2 c2o7pA_ 100.0 97 PDB header:hydrolase, oxidoreductase Chain: A: PDB Molecule:riboflavin biosynthesis protein ribd; PDBTitle: the crystal structure of ribd from escherichia coli in complex with2 the oxidised nadp+ cofactor in the active site of the reductase3 domain 3 c2hxvA_ 100.0 34 PDB header:biosynthetic protein Chain: A: PDB Molecule:diaminohydroxyphosphoribosylaminopyrimidine deaminase/ 5- PDBTitle: crystal structure of a diaminohydroxyphosphoribosylaminopyrimidine2 deaminase/ 5-amino-6-(5-phosphoribosylamino)uracil reductase (tm1828)3 from thermotoga maritima at 1.80 a resolution 4 d2b3za1 100.0 32 Fold:Dihydrofolate reductase-like Superfamily:Dihydrofolate reductase-like Family:RibD C-terminal domain-like 5 d2azna1 100.0 32 Fold:Dihydrofolate reductase-like Superfamily:Dihydrofolate reductase-like Family:RibD C-terminal domain-like 6 c2p4gA_ 100.0 16 PDB header:oxidoreductase Chain: A: PDB Molecule:hypothetical protein; PDBTitle: crystal structure of a pyrimidine reductase-like protein (dip1392)2 from corynebacterium diphtheriae nctc at 2.30 a resolution 7 d2b3za2 100.0 57 Fold:Cytidine deaminase-like Superfamily:Cytidine deaminase-like Family:Deoxycytidylate deaminase-like 8 d2hxva1 100.0 26 Fold:Dihydrofolate reductase-like Superfamily:Dihydrofolate reductase-like Family:RibD C-terminal domain-like 9 d2hxva2 100.0 44 Fold:Cytidine deaminase-like Superfamily:Cytidine deaminase-like Family:Deoxycytidylate deaminase-like 10 d1z3aa1 100.0 33 Fold:Cytidine deaminase-like Superfamily:Cytidine deaminase-like Family:Deoxycytidylate deaminase-like 11 c3ocqA_ 100.0 33 PDB header:hydrolase Chain: A: PDB Molecule:putative cytosine/adenosine deaminase; PDBTitle: crystal structure of trna-specific adenosine deaminase from salmonella2 enterica 12 c2nx8A_ 100.0 28 PDB header:hydrolase Chain: A: PDB Molecule:trna-specific adenosine deaminase; PDBTitle: the crystal structure of the trna-specific adenosine deaminase from2 streptococcus pyogenes 13 d2b3ja1 100.0 30 Fold:Cytidine deaminase-like Superfamily:Cytidine deaminase-like Family:Deoxycytidylate deaminase-like 14 d2g84a1 100.0 25 Fold:Cytidine deaminase-like Superfamily:Cytidine deaminase-like Family:Deoxycytidylate deaminase-like 15 c3kgyA_ 100.0 14 PDB header:oxidoreductase Chain: A: PDB Molecule:bifunctional deaminase-reductase domain protein; PDBTitle: crystal structure of putative dihydrofolate reductase (yp_001636057.1)2 from chloroflexus aurantiacus j-10-fl at 1.50 a resolution 16 d1wwra1 100.0 30 Fold:Cytidine deaminase-like Superfamily:Cytidine deaminase-like Family:Deoxycytidylate deaminase-like 17 d1p6oa_ 100.0 28 Fold:Cytidine deaminase-like Superfamily:Cytidine deaminase-like Family:Deoxycytidylate deaminase-like 18 c3jtwB_ 100.0 18 PDB header:oxidoreductase Chain: B: PDB Molecule:dihydrofolate reductase; PDBTitle: crystal structure of putative dihydrofolate reductase (yp_805003.1)2 from pediococcus pentosaceus atcc 25745 at 1.90 a resolution 19 c3dh1D_ 100.0 29 PDB header:hydrolase Chain: D: PDB Molecule:trna-specific adenosine deaminase 2; PDBTitle: crystal structure of human trna-specific adenosine-34 deaminase2 subunit adat2 20 c2gd9A_ 100.0 19 PDB header:oxidoreductase Chain: A: PDB Molecule:hypothetical protein yyap; PDBTitle: crystal structure of a putative dihydrofolate reductase (bsu40760,2 yyap) from bacillus subtilis at 2.30 a resolution 21 c2xw7A_ not modelled 100.0 18 PDB header:oxidoreductase Chain: A: PDB Molecule:dihydrofolate reductase; PDBTitle: structure of mycobacterium smegmatis putative reductase ms0308 22 d1d1ga_ not modelled 100.0 21 Fold:Dihydrofolate reductase-like Superfamily:Dihydrofolate reductase-like Family:Dihydrofolate reductases 23 d1wkqa_ not modelled 100.0 27 Fold:Cytidine deaminase-like Superfamily:Cytidine deaminase-like Family:Deoxycytidylate deaminase-like 24 d1vq2a_ not modelled 100.0 36 Fold:Cytidine deaminase-like Superfamily:Cytidine deaminase-like Family:Deoxycytidylate deaminase-like 25 d2a8na1 not modelled 100.0 33 Fold:Cytidine deaminase-like Superfamily:Cytidine deaminase-like Family:Deoxycytidylate deaminase-like 26 c2w4lC_ not modelled 100.0 32 PDB header:hydrolase Chain: C: PDB Molecule:deoxycytidylate deaminase; PDBTitle: human dcmp deaminase 27 c2hvwC_ not modelled 100.0 31 PDB header:hydrolase Chain: C: PDB Molecule:deoxycytidylate deaminase; PDBTitle: crystal structure of dcmp deaminase from streptococcus2 mutans 28 c3ky8B_ not modelled 100.0 21 PDB header:biosynthetic protein Chain: B: PDB Molecule:putative riboflavin biosynthesis protein; PDBTitle: crystal structure of putative riboflavin biosynthesis protein2 (yp_001092907.1) from shewanella sp. pv-4 at 2.12 a resolution 29 d1seja1 not modelled 99.7 14 Fold:Dihydrofolate reductase-like Superfamily:Dihydrofolate reductase-like Family:Dihydrofolate reductases 30 d1vdra_ not modelled 99.6 13 Fold:Dihydrofolate reductase-like Superfamily:Dihydrofolate reductase-like Family:Dihydrofolate reductases 31 c3ix9B_ not modelled 99.5 18 PDB header:oxidoreductase Chain: B: PDB Molecule:dihydrofolate reductase; PDBTitle: crystal structure of streptococcus pneumoniae dihydrofolate2 reductase - sp9 mutant 32 d3dfra_ not modelled 99.4 15 Fold:Dihydrofolate reductase-like Superfamily:Dihydrofolate reductase-like Family:Dihydrofolate reductases 33 d1kmva_ not modelled 99.4 16 Fold:Dihydrofolate reductase-like Superfamily:Dihydrofolate reductase-like Family:Dihydrofolate reductases 34 c3k2hA_ not modelled 99.3 17 PDB header:transferase Chain: A: PDB Molecule:dihydrofolate reductase/thymidylate synthase; PDBTitle: co-crystal structure of dihydrofolate reductase/thymidylate synthase2 from babesia bovis with dump, pemetrexed and nadp 35 d8dfra_ not modelled 99.3 18 Fold:Dihydrofolate reductase-like Superfamily:Dihydrofolate reductase-like Family:Dihydrofolate reductases 36 d2fzia1 not modelled 99.2 20 Fold:Dihydrofolate reductase-like Superfamily:Dihydrofolate reductase-like Family:Dihydrofolate reductases 37 c3e0bA_ not modelled 99.2 15 PDB header:oxidoreductase Chain: A: PDB Molecule:dihydrofolate reductase; PDBTitle: bacillus anthracis dihydrofolate reductase complexed with2 nadph and 2,4-diamino-5-(3-(2,5-dimethoxyphenyl)prop-1-3 ynyl)-6-ethylpyrimidine (ucp120b) 38 c1zdrB_ not modelled 99.2 18 PDB header:oxidoreductase Chain: B: PDB Molecule:dihydrofolate reductase; PDBTitle: dhfr from bacillus stearothermophilus 39 d1df7a_ not modelled 99.2 17 Fold:Dihydrofolate reductase-like Superfamily:Dihydrofolate reductase-like Family:Dihydrofolate reductases 40 c3tq8A_ not modelled 99.2 17 PDB header:oxidoreductase/oxidoreductase inhibitor Chain: A: PDB Molecule:dihydrofolate reductase; PDBTitle: structure of the dihydrofolate reductase (fola) from coxiella burnetii2 in complex with trimethoprim 41 c3ia5A_ not modelled 99.1 14 PDB header:oxidoreductase Chain: A: PDB Molecule:dihydrofolate reductase; PDBTitle: moritella profunda dihydrofolate reductase (dhfr) 42 d1ra9a_ not modelled 99.1 14 Fold:Dihydrofolate reductase-like Superfamily:Dihydrofolate reductase-like Family:Dihydrofolate reductases 43 c2oipE_ not modelled 99.0 18 PDB header:transferase, oxidoreductase Chain: E: PDB Molecule:chain a, crystal structure of dhfr; PDBTitle: crystal structure of the s290g active site mutant of ts-2 dhfr from cryptosporidium hominis 44 c3f0uX_ not modelled 99.0 16 PDB header:oxidoreductase Chain: X: PDB Molecule:trimethoprim-sensitive dihydrofolate reductase; PDBTitle: staphylococcus aureus f98y mutant dihydrofolate reductase2 complexed with nadph and 2,4-diamino-5-[3-(3-methoxy-5-3 phenylphenyl)but-1-ynyl]-6-methylpyrimidine 45 d1j3ka_ not modelled 98.9 12 Fold:Dihydrofolate reductase-like Superfamily:Dihydrofolate reductase-like Family:Dihydrofolate reductases 46 d1aoea_ not modelled 98.8 12 Fold:Dihydrofolate reductase-like Superfamily:Dihydrofolate reductase-like Family:Dihydrofolate reductases 47 c2blcA_ not modelled 98.7 14 PDB header:oxidoreductase Chain: A: PDB Molecule:dihydrofolate reductase-thymidylate synthase; PDBTitle: sp21 double mutant p. vivax dihydrofolate reductase in2 complex with des-chloropyrimethamine 48 c3dg8B_ not modelled 98.7 13 PDB header:oxidoreductase, transferase Chain: B: PDB Molecule:bifunctional dihydrofolate reductase-thymidylate PDBTitle: quadruple mutant (n51i+c59r+s108n+i164l) plasmodium2 falciparum dihydrofolate reductase-thymidylate synthase3 (pfdhfr-ts) complexed with rjf670, nadph, and dump 49 c3jsuA_ not modelled 98.7 12 PDB header:oxidoreductase, transferase Chain: A: PDB Molecule:dihydrofolate reductase-thymidylate synthase; PDBTitle: quadruple mutant(n51i+c59r+s108n+i164l) plasmodium falciparum2 dihydrofolate reductase-thymidylate synthase(pfdhfr-ts) complexed3 with qn254, nadph, and dump 50 c3clbA_ not modelled 98.7 14 PDB header:oxidoreductase, transferase Chain: A: PDB Molecule:dhfr-ts; PDBTitle: structure of bifunctional tcdhfr-ts in complex with tmq 51 c3cseA_ not modelled 98.5 15 PDB header:oxidoreductase Chain: A: PDB Molecule:dihydrofolate reductase; PDBTitle: candida glabrata dihydrofolate reductase complexed with2 nadph and 2,4-diamino-5-(3-(2,5-dimethoxyphenyl)prop-1-3 ynyl)-6-ethylpyrimidine (ucp120b) 52 c3rg9A_ not modelled 98.1 16 PDB header:oxidoreductase/oxidoreductase inhibitor Chain: A: PDB Molecule:bifunctional dihydrofolate reductase-thymidylate synthase; PDBTitle: trypanosoma brucei dihydrofolate reductase (tbdhfr) in complex with2 wr99210 53 d1uwza_ not modelled 97.7 21 Fold:Cytidine deaminase-like Superfamily:Cytidine deaminase-like Family:Cytidine deaminase 54 c3g8qA_ not modelled 97.7 34 PDB header:rna binding protein Chain: A: PDB Molecule:predicted rna-binding protein, contains thump PDBTitle: a cytidine deaminase edits c-to-u in transfer rnas in2 archaea 55 d2d30a1 not modelled 97.6 21 Fold:Cytidine deaminase-like Superfamily:Cytidine deaminase-like Family:Cytidine deaminase 56 d1juva_ not modelled 97.5 22 Fold:Dihydrofolate reductase-like Superfamily:Dihydrofolate reductase-like Family:Dihydrofolate reductases 57 d1alna1 not modelled 97.4 26 Fold:Cytidine deaminase-like Superfamily:Cytidine deaminase-like Family:Cytidine deaminase 58 c3ijfX_ not modelled 97.3 19 PDB header:hydrolase Chain: X: PDB Molecule:cytidine deaminase; PDBTitle: crystal structure of cytidine deaminase from mycobacterium2 tuberculosis 59 d1r5ta_ not modelled 97.2 20 Fold:Cytidine deaminase-like Superfamily:Cytidine deaminase-like Family:Cytidine deaminase 60 c3dmoD_ not modelled 97.1 25 PDB header:hydrolase Chain: D: PDB Molecule:cytidine deaminase; PDBTitle: 1.6 a crystal structure of cytidine deaminase from2 burkholderia pseudomallei 61 c1alnA_ not modelled 97.0 25 PDB header:hydrolase Chain: A: PDB Molecule:cytidine deaminase; PDBTitle: crystal structure of cytidine deaminase complexed with 3-deazacytidine 62 d1mq0a_ not modelled 97.0 20 Fold:Cytidine deaminase-like Superfamily:Cytidine deaminase-like Family:Cytidine deaminase 63 c3r2nC_ not modelled 96.9 19 PDB header:hydrolase Chain: C: PDB Molecule:cytidine deaminase; PDBTitle: crystal structure of cytidine deaminase from mycobacterium leprae 64 c2nytB_ not modelled 96.8 19 PDB header:hydrolase Chain: B: PDB Molecule:probable c->u-editing enzyme apobec-2; PDBTitle: the apobec2 crystal structure and functional implications2 for aid 65 d2fr5a1 not modelled 96.8 14 Fold:Cytidine deaminase-like Superfamily:Cytidine deaminase-like Family:Cytidine deaminase 66 c3oj6C_ not modelled 96.3 24 PDB header:hydrolase Chain: C: PDB Molecule:blasticidin-s deaminase; PDBTitle: crystal structure of blasticidin s deaminase from coccidioides immitis 67 d2z3ga1 not modelled 96.2 21 Fold:Cytidine deaminase-like Superfamily:Cytidine deaminase-like Family:Cytidine deaminase 68 c3b8fB_ not modelled 96.1 14 PDB header:hydrolase Chain: B: PDB Molecule:putative blasticidin s deaminase; PDBTitle: crystal structure of the cytidine deaminase from bacillus anthracis 69 c2kboA_ not modelled 95.8 22 PDB header:hydrolase Chain: A: PDB Molecule:dna dc->du-editing enzyme apobec-3g; PDBTitle: structure, interaction, and real-time monitoring of the2 enzymatic reaction of wild type apobec3g 70 d1alna2 not modelled 95.7 16 Fold:Cytidine deaminase-like Superfamily:Cytidine deaminase-like Family:Cytidine deaminase 71 d1j5ta_ not modelled 74.9 13 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 72 d1o60a_ not modelled 71.5 14 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 73 c3qjaA_ not modelled 66.4 15 PDB header:lyase Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase; PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form 74 d1zcza2 not modelled 65.3 42 Fold:Cytidine deaminase-like Superfamily:Cytidine deaminase-like Family:AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC 75 c4a1oB_ not modelled 59.6 37 PDB header:transferase-hydrolase Chain: B: PDB Molecule:bifunctional purine biosynthesis protein purh; PDBTitle: crystal structure of mycobacterium tuberculosis purh complexed with2 aicar and a novel nucleotide cfair, at 2.48 a resolution. 76 c2h6rG_ not modelled 54.2 11 PDB header:isomerase Chain: G: PDB Molecule:triosephosphate isomerase; PDBTitle: crystal structure of triosephosphate isomerase (tim) from2 methanocaldococcus jannaschii 77 c2gm2A_ not modelled 53.5 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein; PDBTitle: nmr structure of xanthomonas campestris xcc1710: northeast2 structural genomics consortium target xcr35 78 c2xecD_ not modelled 49.8 20 PDB header:isomerase Chain: D: PDB Molecule:putative maleate isomerase; PDBTitle: nocardia farcinica maleate cis-trans isomerase bound to2 tris 79 c1zczA_ not modelled 49.0 42 PDB header:transferase/hydrolase Chain: A: PDB Molecule:bifunctional purine biosynthesis protein purh; PDBTitle: crystal structure of phosphoribosylaminoimidazolecarboxamide2 formyltransferase / imp cyclohydrolase (tm1249) from thermotoga3 maritima at 1.88 a resolution 80 d1o13a_ not modelled 47.2 15 Fold:Ribonuclease H-like motif Superfamily:Nitrogenase accessory factor-like Family:MTH1175-like 81 d1d9ea_ not modelled 46.8 14 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 82 c2wfbA_ not modelled 46.7 27 PDB header:biosynthetic protein Chain: A: PDB Molecule:putative uncharacterized protein orp; PDBTitle: high resolution structure of the apo form of the orange2 protein (orp) from desulfovibrio gigas 83 c1piiA_ not modelled 46.4 25 PDB header:bifunctional(isomerase and synthase) Chain: A: PDB Molecule:n-(5'phosphoribosyl)anthranilate isomerase; PDBTitle: three-dimensional structure of the bifunctional enzyme2 phosphoribosylanthranilate isomerase:3 indoleglycerolphosphate synthase from escherichia coli4 refined at 2.0 angstroms resolution 84 d1i4na_ not modelled 45.0 16 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 85 c2c3zA_ not modelled 44.1 14 PDB header:lyase Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase; PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus 86 d1piia2 not modelled 43.7 22 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 87 c2yx6C_ not modelled 40.7 16 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:hypothetical protein ph0822; PDBTitle: crystal structure of ph0822 88 c2c4kD_ not modelled 40.1 8 PDB header:regulatory protein Chain: D: PDB Molecule:phosphoribosyl pyrophosphate synthetase- PDBTitle: crystal structure of human phosphoribosylpyrophosphate2 synthetase-associated protein 39 (pap39) 89 c3sz8D_ not modelled 39.7 14 PDB header:transferase Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 2; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia pseudomallei 90 d1a53a_ not modelled 38.2 19 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 91 d2fb5a1 not modelled 37.7 35 Fold:YojJ-like Superfamily:YojJ-like Family:YojJ-like 92 c2k2eA_ not modelled 37.3 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein bp2786; PDBTitle: solution nmr structure of bordetella pertussis protein2 bp2786, a mth938-like domain. northeast structural3 genomics consortium target ber31 93 c2gewA_ not modelled 36.7 24 PDB header:oxidoreductase Chain: A: PDB Molecule:cholesterol oxidase; PDBTitle: atomic resolution structure of cholesterol oxidase @ ph 9.02 (streptomyces sp. sa-coo) 94 d2q4qa1 not modelled 36.5 21 Fold:MTH938-like Superfamily:MTH938-like Family:MTH938-like 95 d1xk7a1 not modelled 35.9 15 Fold:CoA-transferase family III (CaiB/BaiF) Superfamily:CoA-transferase family III (CaiB/BaiF) Family:CoA-transferase family III (CaiB/BaiF) 96 d1g5ha1 not modelled 34.3 23 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 97 d1zbfa1 not modelled 33.0 23 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Ribonuclease H 98 c3gxgA_ not modelled 31.8 18 PDB header:hydrolase Chain: A: PDB Molecule:putative phosphatase (duf442); PDBTitle: crystal structure of putative phosphatase (duf442) (yp_001181608.1)2 from shewanella putrefaciens cn-32 at 1.60 a resolution 99 d1u9ya2 not modelled 31.1 23 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 100 d1vc4a_ not modelled 30.6 16 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 101 c3efhB_ not modelled 29.6 28 PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase 1; PDBTitle: crystal structure of human phosphoribosyl pyrophosphate2 synthetase 1 102 c3b0vD_ not modelled 29.4 11 PDB header:oxidoreductase/rna Chain: D: PDB Molecule:trna-dihydrouridine synthase; PDBTitle: trna-dihydrouridine synthase from thermus thermophilus in complex with2 trna 103 d2f5va1 not modelled 29.3 24 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD-linked reductases, N-terminal domain 104 d1ewna_ not modelled 28.7 28 Fold:FMT C-terminal domain-like Superfamily:FMT C-terminal domain-like Family:3-methyladenine DNA glycosylase (AAG, ANPG, MPG) 105 d1eo1a_ not modelled 28.7 23 Fold:Ribonuclease H-like motif Superfamily:Nitrogenase accessory factor-like Family:MTH1175-like 106 c1u9yD_ not modelled 28.7 25 PDB header:transferase Chain: D: PDB Molecule:ribose-phosphate pyrophosphokinase; PDBTitle: crystal structure of phosphoribosyl diphosphate synthase2 from methanocaldococcus jannaschii 107 d2fi9a1 not modelled 28.2 6 Fold:MTH938-like Superfamily:MTH938-like Family:MTH938-like 108 c3ggmB_ not modelled 27.7 30 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein bt9727_2919; PDBTitle: crystal structure of bt9727_2919 from bacillus2 thuringiensis subsp. northeast structural genomics target3 bur228b 109 c2jugB_ not modelled 27.5 21 PDB header:biosynthetic protein Chain: B: PDB Molecule:tubc protein; PDBTitle: multienzyme docking in hybrid megasynthetases 110 d1znna1 not modelled 26.8 16 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:PdxS-like 111 d1rdua_ not modelled 26.5 23 Fold:Ribonuclease H-like motif Superfamily:Nitrogenase accessory factor-like Family:MTH1175-like 112 d1dkua2 not modelled 26.5 25 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 113 d1wu7a1 not modelled 26.1 15 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 114 c1znnF_ not modelled 25.7 16 PDB header:biosynthetic protein Chain: F: PDB Molecule:plp synthase; PDBTitle: structure of the synthase subunit of plp synthase 115 d2g4ca1 not modelled 25.4 20 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 116 d1t3va_ not modelled 24.4 13 Fold:Ribonuclease H-like motif Superfamily:Nitrogenase accessory factor-like Family:MTH1175-like 117 d1w0ma_ not modelled 24.0 32 Fold:TIM beta/alpha-barrel Superfamily:Triosephosphate isomerase (TIM) Family:Triosephosphate isomerase (TIM) 118 d2vjma1 not modelled 23.5 9 Fold:CoA-transferase family III (CaiB/BaiF) Superfamily:CoA-transferase family III (CaiB/BaiF) Family:CoA-transferase family III (CaiB/BaiF) 119 d2fvta1 not modelled 22.4 5 Fold:MTH938-like Superfamily:MTH938-like Family:MTH938-like 120 c2qtdA_ not modelled 22.3 8 PDB header:oxidoreductase Chain: A: PDB Molecule:uncharacterized protein mj0327; PDBTitle: crystal structure of a putative dinitrogenase (mj0327) from2 methanocaldococcus jannaschii dsm at 1.70 a resolution

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0