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  Protein Homology/analogY Recognition Engine V 2.2
 

Fold library entry viewer: c2oipE_

Fold library idPDB HeaderMoleculeTitle
c2oipE_PDB header: transferase, oxidoreductaseChain: E: PDB Molecule: chain a, crystal structure of dhfr;PDBTitle: crystal structure of the s290g active site mutant of ts-2 dhfr from cryptosporidium hominis


Added to library: Tue Mar 16 12:43:08 2010
 
Links to external resources


 1........10.........20.........30.........40.........50.........60.........70
Sequence EKNVSIVVAASVLSSGIGINGQLPWSISEDLKFFSKITNNKCDSNKKNALIMGRKTWDSIGRRPLKNRII
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Known secondary structure (DSSP)


TTT
BTTB
SS



S
TTSTS


TT
 .........80.........90.........100.........110.........120.........130.........140
Sequence VVISSSLPQDEADPNVVVFRNLEDSIENLMNDDSIENIFVCGGESIYRDALKDNFVDRIYLTRVALEDIE
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Known secondary structure (DSSP)
SSS


TT
TTSSTTGGGGTTTT

S
TT

S


SS
 .........150.........160.........170.........180.........190.........200.........210
Sequence FDTYFPEIPETFLPVYMSQTFCTKNISYDFMIFEKQEKKTGQLKSIDDTVDLLGEIFGIRKMGNRHKFPK
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Known secondary structure (DSSP)
S




TT


TT

S



SSSTTTSSTTSS



 .........220.........230.........240.........250.........260.........270.........280
Sequence EEIYNTPSIRFGREHYEFQYLDLLSRVLENGAYRENRTGISTYSIFGQMMRFDMRESFPLLTTKKVAIRG
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Known secondary structure (DSSP) GGGSSSTT
SS
STTS


SSSS

SSS



SSS


 .........290.........300.........310.........320.........330.........340.........350
Sequence IFEELIWFIKGDTNGNHLIEKKVYIWSGNGSKEYLERIGLGHREENDLGPIYGFQWRHYNGEYKTMHDDY
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Known secondary structure (DSSP) T


TTT

TTTTTTSTTTTTS
SS


S

BT




SSS

 .........360.........370.........380.........390.........400.........410.........420
Sequence TGVGVDQLAKLIETLKNNPKDRRHILTAWNPSALSQMALPPCHVLSQYYVTNDNCLSCNLYQRSCDLGLG
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Known secondary structure (DSSP) TT
SB


S
TT



TTTGGGSSS

S
TTSTTT
 .........430.........440.........450.........460.........470.........480.........490
Sequence SPFNIASYAILTMMLAQVCGYEPGELAIFIGDAHIYENHLTQLKEQLSRTPRPFPQLKFKRKVENIEDFK
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Known secondary structure (DSSP) TT
TTSS





SS

SSGGG

 .........500.........510.
Sequence WEDIELIGYYPYPTIKMDMAV
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Known secondary structure (DSSP) STTS













Download:PDB structure FASTA sequence

Hidden Markov model

Image coloured by rainbow N → C terminus
Interactive 3D view in JSmol


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Accessibility Statement
Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction
Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960
 
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