Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionQ00042
DateThu Jan 5 12:33:20 GMT 2012
Unique Job IDf0933668b5048262

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1w5sa2
Top template information
Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Extended AAA-ATPase domain
Confidence and coverage
Confidence: 98.6% Coverage: 32%
223 residues ( 32% of your sequence) have been modelled with 98.6% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
378 residues ( 54%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MELNITSKSNPFGDTTAENDKKMLSNAFIETADFRTLIETDDRTIVVGRRGTGKSALFIQ
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Disorder  ????????
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   .........70.........80.........90.........100.........110.........120
Sequence  LNEHWKKDKKILILSFSPDDSQIIGFRSMLKPFTGSFNLARAATRLLWRYAMLMEIASYI
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Disorder 


??
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?
?

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   .........130.........140.........150.........160.........170.........180
Sequence  SSHYKLSSQISSETLLNEHLKKWNSAQGDILRKCRLVAKEYLDENNPEESIGDLQFNLNI
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Disorder 
?
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??

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   .........190.........200.........210.........220.........230.........240
Sequence  SEIENNIVSLLERSDRKVVILMDKLDEAYEPDNIGIGIIAGLAYASIELNQKAKCIRPII
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   .........250.........260.........270.........280.........290.........300
Sequence  FLRDNIFRSLSKEDPDYSRNIEGQVIRLHWDWAQLLMLSAKRMKVAFKLDIEKDQRVWDR
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???????



























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   .........310.........320.........330.........340.........350.........360
Sequence  CTADDLKGRNGFKRCLQFTLYRPRDLLSLLNEAFFSAFRENRETIINTDLEYAAKSISMA
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Disorder 

???????





























???

















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   .........370.........380.........390.........400.........410.........420
Sequence  RLEDLWKEYQKIFPSIQVITSAFRSIEPELTVYTCLKKIEASFELIEENGDPKITSEIQL
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Disorder 

























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?????




??
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   .........430.........440.........450.........460.........470.........480
Sequence  LKASGILQSLYSVGFVGIRDKNTSSYSFCHDGRTPDKGFESNEKLLIHPCYWLGLNLNRN
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Disorder 































?
??
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?
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   .........490.........500.........510.........520.........530.........540
Sequence  ALAPEEAEEINDEYDINIISDNSAIRNKTIGQITTHLDQIPIGNEGATEFEQWCLDALRI
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Disorder  ??????




?????




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   .........550.........560.........570.........580.........590.........600
Sequence  VFASHLTDIKSHPNGNAVQRRDIIGTNGGKSDFWKRVLEDYKTRQVVFDAKNFEELGPSE
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   .........610.........620.........630.........640.........650.........660
Sequence  YRQLQSYLTGPYGKLGFIINRDESEVLKSGKDLDWTKEMYQSHNSLIIKLPAKYISKLLQ
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Disorder 





?















??????






























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   .........670.........680.........690........
Sequence  KLRNPEKHDAIDRQMGKLLTLYETSYMAIKSTQKKRRK
Secondary structure 







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Disorder 




????



















?????????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1w5s chain A domain 2

3D model

Region: 44 - 356
Aligned: 223
Modelled: 223
Confidence: 98.6%
Identity: 15%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: Extended AAA-ATPase domain

Phyre2

PDB 1fnn chain A domain 2

3D model

Region: 42 - 356
Aligned: 229
Modelled: 235
Confidence: 98.1%
Identity: 18%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: Extended AAA-ATPase domain

Phyre2

PDB 1w5s chain B

3D model

Region: 19 - 450
Aligned: 333
Modelled: 343
Confidence: 97.6%
Identity: 15%
PDB header:replication
Chain: B: PDB Molecule:origin recognition complex subunit 2 orc2;
PDBTitle: structure of the aeropyrum pernix orc2 protein (adp form)

Phyre2

PDB 2ce7 chain A domain 2

3D model

Region: 12 - 357
Aligned: 223
Modelled: 231
Confidence: 97.1%
Identity: 19%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: Extended AAA-ATPase domain

Phyre2

PDB 2qby chain A

3D model

Region: 39 - 446
Aligned: 302
Modelled: 320
Confidence: 96.9%
Identity: 20%
PDB header:replication/dna
Chain: A: PDB Molecule:cell division control protein 6 homolog 1;
PDBTitle: crystal structure of a heterodimer of cdc6/orc1 initiators2 bound to origin dna (from s. solfataricus)

Phyre2

PDB 2v1u chain A

3D model

Region: 39 - 436
Aligned: 302
Modelled: 328
Confidence: 96.7%
Identity: 15%
PDB header:replication
Chain: A: PDB Molecule:cell division control protein 6 homolog;
PDBTitle: structure of the aeropyrum pernix orc1 protein in complex2 with dna

Phyre2

PDB 2fna chain A domain 2

3D model

Region: 25 - 372
Aligned: 259
Modelled: 277
Confidence: 96.2%
Identity: 16%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: Extended AAA-ATPase domain

Phyre2

PDB 3h4m chain C

3D model

Region: 38 - 361
Aligned: 209
Modelled: 225
Confidence: 96.0%
Identity: 20%
PDB header:hydrolase
Chain: C: PDB Molecule:proteasome-activating nucleotidase;
PDBTitle: aaa atpase domain of the proteasome- activating nucleotidase

Phyre2

PDB 1ixz chain A

3D model

Region: 38 - 353
Aligned: 197
Modelled: 204
Confidence: 95.8%
Identity: 18%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: Extended AAA-ATPase domain

Phyre2

PDB 1fnn chain B

3D model

Region: 20 - 356
Aligned: 251
Modelled: 263
Confidence: 95.6%
Identity: 19%
PDB header:cell cycle
Chain: B: PDB Molecule:cell division control protein 6;
PDBTitle: crystal structure of cdc6p from pyrobaculum aerophilum

Phyre2

PDB 2c9o chain C

3D model

Region: 40 - 368
Aligned: 249
Modelled: 255
Confidence: 95.5%
Identity: 16%
PDB header:hydrolase
Chain: C: PDB Molecule:ruvb-like 1;
PDBTitle: 3d structure of the human ruvb-like helicase ruvbl1

Phyre2

PDB 2x77 chain B

3D model

Region: 27 - 78
Aligned: 52
Modelled: 52
Confidence: 95.0%
Identity: 15%
PDB header:gtp-binding protein
Chain: B: PDB Molecule:adp-ribosylation factor;
PDBTitle: crystal structure of leishmania major adp ribosylation2 factor-like 1.

Phyre2

PDB 2fna chain A

3D model

Region: 41 - 450
Aligned: 311
Modelled: 339
Confidence: 94.9%
Identity: 18%
PDB header:atp-binding protein
Chain: A: PDB Molecule:conserved hypothetical protein;
PDBTitle: crystal structure of an archaeal aaa+ atpase (sso1545) from sulfolobus2 solfataricus p2 at 2.00 a resolution

Phyre2

PDB 1iy2 chain A

3D model

Region: 12 - 353
Aligned: 223
Modelled: 235
Confidence: 94.9%
Identity: 24%
PDB header:hydrolase
Chain: A: PDB Molecule:atp-dependent metalloprotease ftsh;
PDBTitle: crystal structure of the ftsh atpase domain from thermus2 thermophilus

Phyre2

PDB 1g6o chain A

3D model

Region: 34 - 107
Aligned: 73
Modelled: 74
Confidence: 94.8%
Identity: 16%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: RecA protein-like (ATPase-domain)

Phyre2

PDB 2z4r chain B

3D model

Region: 40 - 357
Aligned: 203
Modelled: 210
Confidence: 94.6%
Identity: 15%
PDB header:dna binding protein
Chain: B: PDB Molecule:chromosomal replication initiator protein dnaa;
PDBTitle: crystal structure of domain iii from the thermotoga2 maritima replication initiation protein dnaa

Phyre2

PDB 2ccj chain A

3D model

Region: 42 - 115
Aligned: 74
Modelled: 74
Confidence: 94.3%
Identity: 15%
PDB header:transferase
Chain: A: PDB Molecule:thymidylate kinase;
PDBTitle: crystal structure of s. aureus thymidylate kinase complexed2 with thymidine monophosphate

Phyre2

PDB 2oaq chain 1

3D model

Region: 34 - 79
Aligned: 46
Modelled: 46
Confidence: 94.0%
Identity: 22%
PDB header:hydrolase
Chain: 1: PDB Molecule:type ii secretion system protein;
PDBTitle: crystal structure of the archaeal secretion atpase gspe in complex2 with phosphate

Phyre2

PDB 1lv7 chain A

3D model

Region: 36 - 356
Aligned: 204
Modelled: 204
Confidence: 93.9%
Identity: 20%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: Extended AAA-ATPase domain

Phyre2

PDB 1in8 chain A

3D model

Region: 42 - 383
Aligned: 210
Modelled: 224
Confidence: 93.9%
Identity: 12%
PDB header:dna binding protein
Chain: A: PDB Molecule:holliday junction dna helicase ruvb;
PDBTitle: thermotoga maritima ruvb t158v

Phyre2
1

d1w5sa2
2

d1fnna2
3

c1w5sB_
4

d2ce7a2
5

c2qbyA_
6

c2v1uA_
7

d2fnaa2
8

c3h4mC_
9

d1ixza_
10

c1fnnB_
11

c2c9oC_
12

c2x77B_
13

c2fnaA_
14

c1iy2A_
15

d1g6oa_
16

c2z4rB_
17

c2ccjA_
18

c2oaq1_
19

d1lv7a_
20

c1in8A_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1w5sa2



98.6 15 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Extended AAA-ATPase domain
2d1fnna2



98.1 18 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Extended AAA-ATPase domain
3c1w5sB_



97.6 15 PDB header:replication
Chain: B: PDB Molecule:origin recognition complex subunit 2 orc2;
PDBTitle: structure of the aeropyrum pernix orc2 protein (adp form)
4d2ce7a2



97.1 19 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Extended AAA-ATPase domain
5c2qbyA_



96.9 20 PDB header:replication/dna
Chain: A: PDB Molecule:cell division control protein 6 homolog 1;
PDBTitle: crystal structure of a heterodimer of cdc6/orc1 initiators2 bound to origin dna (from s. solfataricus)
6c2v1uA_



96.7 15 PDB header:replication
Chain: A: PDB Molecule:cell division control protein 6 homolog;
PDBTitle: structure of the aeropyrum pernix orc1 protein in complex2 with dna
7d2fnaa2



96.2 16 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Extended AAA-ATPase domain
8c3h4mC_



96.0 20 PDB header:hydrolase
Chain: C: PDB Molecule:proteasome-activating nucleotidase;
PDBTitle: aaa atpase domain of the proteasome- activating nucleotidase
9d1ixza_



95.8 18 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Extended AAA-ATPase domain
10c1fnnB_



95.6 19 PDB header:cell cycle
Chain: B: PDB Molecule:cell division control protein 6;
PDBTitle: crystal structure of cdc6p from pyrobaculum aerophilum
11c2c9oC_



95.5 16 PDB header:hydrolase
Chain: C: PDB Molecule:ruvb-like 1;
PDBTitle: 3d structure of the human ruvb-like helicase ruvbl1
12c2x77B_



95.0 15 PDB header:gtp-binding protein
Chain: B: PDB Molecule:adp-ribosylation factor;
PDBTitle: crystal structure of leishmania major adp ribosylation2 factor-like 1.
13c2fnaA_



94.9 18 PDB header:atp-binding protein
Chain: A: PDB Molecule:conserved hypothetical protein;
PDBTitle: crystal structure of an archaeal aaa+ atpase (sso1545) from sulfolobus2 solfataricus p2 at 2.00 a resolution
14c1iy2A_



94.9 24 PDB header:hydrolase
Chain: A: PDB Molecule:atp-dependent metalloprotease ftsh;
PDBTitle: crystal structure of the ftsh atpase domain from thermus2 thermophilus
15d1g6oa_



94.8 16 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:RecA protein-like (ATPase-domain)
16c2z4rB_



94.6 15 PDB header:dna binding protein
Chain: B: PDB Molecule:chromosomal replication initiator protein dnaa;
PDBTitle: crystal structure of domain iii from the thermotoga2 maritima replication initiation protein dnaa
17c2ccjA_



94.3 15 PDB header:transferase
Chain: A: PDB Molecule:thymidylate kinase;
PDBTitle: crystal structure of s. aureus thymidylate kinase complexed2 with thymidine monophosphate
18c2oaq1_



94.0 22 PDB header:hydrolase
Chain: 1: PDB Molecule:type ii secretion system protein;
PDBTitle: crystal structure of the archaeal secretion atpase gspe in complex2 with phosphate
19d1lv7a_



93.9 20 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Extended AAA-ATPase domain
20c1in8A_



93.9 12 PDB header:dna binding protein
Chain: A: PDB Molecule:holliday junction dna helicase ruvb;
PDBTitle: thermotoga maritima ruvb t158v
21c2gzaB_



not modelled 93.8 22 PDB header:hydrolase
Chain: B: PDB Molecule:type iv secretion system protein virb11;
PDBTitle: crystal structure of the virb11 atpase from the brucella suis type iv2 secretion system in complex with sulphate
22d1svsa1



not modelled 93.7 20 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
23d1xjca_



not modelled 93.7 18 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nitrogenase iron protein-like
24c3oesA_



not modelled 93.6 30 PDB header:hydrolase
Chain: A: PDB Molecule:gtpase rhebl1;
PDBTitle: crystal structure of the small gtpase rhebl1
25d2atxa1



not modelled 93.5 21 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
26d1cr2a_



not modelled 93.5 14 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:RecA protein-like (ATPase-domain)
27c2npiB_



not modelled 93.4 26 PDB header:transcription
Chain: B: PDB Molecule:protein clp1;
PDBTitle: clp1-atp-pcf11 complex
28d2a5ja1



not modelled 93.4 35 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
29d2ocpa1



not modelled 93.3 14 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nucleotide and nucleoside kinases
30c3pfiB_



not modelled 93.1 18 PDB header:hydrolase
Chain: B: PDB Molecule:holliday junction atp-dependent dna helicase ruvb;
PDBTitle: 2.7 angstrom resolution crystal structure of a probable holliday2 junction dna helicase (ruvb) from campylobacter jejuni subsp. jejuni3 nctc 11168 in complex with adenosine-5'-diphosphate
31d1ky3a_



not modelled 93.1 26 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
32c2hupB_



not modelled 93.1 17 PDB header:signaling protein
Chain: B: PDB Molecule:ras-related protein rab-43;
PDBTitle: crystal structure of human rab43 in complex with gdp
33c2qagB_



not modelled 93.0 18 PDB header:cell cycle, structural protein
Chain: B: PDB Molecule:septin-6;
PDBTitle: crystal structure of human septin trimer 2/6/7
34d1z0aa1



not modelled 92.9 35 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
35d1r0wa_



not modelled 92.9 28 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
36c2q3fB_



not modelled 92.9 21 PDB header:protein binding
Chain: B: PDB Molecule:ras-related gtp-binding protein d;
PDBTitle: x-ray crystal structure of putative human ras-related gtp2 binding d in complex with gmppnp
37c2ghiD_



not modelled 92.8 23 PDB header:transport protein
Chain: D: PDB Molecule:transport protein;
PDBTitle: crystal structure of plasmodium yoelii multidrug resistance2 protein 2
38d1z0fa1



not modelled 92.8 39 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
39d1z2aa1



not modelled 92.8 26 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
40d1khta_



not modelled 92.8 11 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nucleotide and nucleoside kinases
41c2nzjB_



not modelled 92.7 32 PDB header:signaling protein
Chain: B: PDB Molecule:gtp-binding protein rem 1;
PDBTitle: the crystal structure of rem1 in complex with gdp
42d1z2ca1



not modelled 92.7 21 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
43d1g16a_



not modelled 92.7 30 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
44d1kmqa_



not modelled 92.7 19 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
45c2olkD_



not modelled 92.7 30 PDB header:hydrolase
Chain: D: PDB Molecule:amino acid abc transporter;
PDBTitle: abc protein artp in complex with adp-beta-s
46d2bmea1



not modelled 92.6 43 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
47c2cbzA_



not modelled 92.6 42 PDB header:transport
Chain: A: PDB Molecule:multidrug resistance-associated protein 1;
PDBTitle: structure of the human multidrug resistance protein 12 nucleotide binding domain 1
48c1zbdA_



not modelled 92.6 13 PDB header:g protein
Chain: A: PDB Molecule:rabphilin-3a;
PDBTitle: structural basis of rab effector specificity: crystal2 structure of the small g protein rab3a complexed with the3 effector domain of rabphilin-3a
49d2bcgy1



not modelled 92.6 21 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
50d2d7ca1



not modelled 92.5 26 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
51d2c2ha1



not modelled 92.5 30 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
52c2ew1A_



not modelled 92.5 22 PDB header:signaling protein
Chain: A: PDB Molecule:ras-related protein rab-30;
PDBTitle: crystal structure of rab30 in complex with a gtp analogue
53d2ew1a1



not modelled 92.5 22 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
54c3nhaA_



not modelled 92.5 29 PDB header:transport protein
Chain: A: PDB Molecule:atp-binding cassette sub-family b member 6, mitochondrial;
PDBTitle: nucleotide binding domain of human abcb6 (adp mg bound structure)
55c2p5sB_



not modelled 92.5 22 PDB header:signaling protein
Chain: B: PDB Molecule:ras and ef-hand domain containing;
PDBTitle: rab domain of human rasef in complex with gdp
56c3t1tC_



not modelled 92.4 14 PDB header:hydrolase
Chain: C: PDB Molecule:gliding protein mgla;
PDBTitle: mgla bound to gdp in p1 tetrameric arrangement
57d1ji0a_



not modelled 92.4 17 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
58c3gfoA_



not modelled 92.4 29 PDB header:atp binding protein
Chain: A: PDB Molecule:cobalt import atp-binding protein cbio 1;
PDBTitle: structure of cbio1 from clostridium perfringens: part of2 the abc transporter complex cbionq.
59c3cphA_



not modelled 92.4 30 PDB header:protein transport
Chain: A: PDB Molecule:ras-related protein sec4;
PDBTitle: crystal structure of sec4 in complex with rab-gdi
60c2qu8A_



not modelled 92.3 29 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative nucleolar gtp-binding protein 1;
PDBTitle: crystal structure of putative nucleolar gtp-binding protein 1 pff0625w2 from plasmodium falciparum
61c2f9lA_



not modelled 92.3 26 PDB header:hydrolase
Chain: A: PDB Molecule:rab11b, member ras oncogene family;
PDBTitle: 3d structure of inactive human rab11b gtpase
62c3lxwA_



not modelled 92.3 45 PDB header:immune system
Chain: A: PDB Molecule:gtpase imap family member 1;
PDBTitle: crystal structure of human gtpase imap family member 1
63c3g5uB_



not modelled 92.2 29 PDB header:membrane protein
Chain: B: PDB Molecule:multidrug resistance protein 1a;
PDBTitle: structure of p-glycoprotein reveals a molecular basis for2 poly-specific drug binding
64d1sgwa_



not modelled 92.2 29 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
65d1wmsa_



not modelled 92.2 30 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
66c2qa5A_



not modelled 92.2 33 PDB header:cell cycle, structural protein
Chain: A: PDB Molecule:septin-2;
PDBTitle: crystal structure of sept2 g-domain
67d3raba_



not modelled 92.2 13 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
68d1yzqa1



not modelled 92.1 17 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
69d2fg5a1



not modelled 92.1 22 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
70c2fg5A_



not modelled 92.1 22 PDB header:signaling protein
Chain: A: PDB Molecule:ras-related protein rab-31;
PDBTitle: crystal structure of human rab31 in complex with a gtp2 analogue
71c3bbpA_



not modelled 92.1 17 PDB header:protein transport/splicing
Chain: A: PDB Molecule:ras-related protein rab-6a;
PDBTitle: rab6-gtp:gcc185 rab binding domain complex
72d2ngra_



not modelled 92.1 20 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
73d1x3sa1



not modelled 92.1 26 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
74c2g3yA_



not modelled 92.0 30 PDB header:signaling protein
Chain: A: PDB Molecule:gtp-binding protein gem;
PDBTitle: crystal structure of the human small gtpase gem
75d2g3ya1



not modelled 92.0 30 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
76c3t5dC_



not modelled 92.0 53 PDB header:signaling protein
Chain: C: PDB Molecule:septin-7;
PDBTitle: crystal structure of septin 7 in complex with gdp
77c2hxsA_



not modelled 92.0 22 PDB header:signaling protein
Chain: A: PDB Molecule:ras-related protein rab-28;
PDBTitle: crystal structure of rab28a gtpase in the inactive (gdp-3'p-2 bound) form
78c2efhD_



not modelled 92.0 32 PDB header:transport protein
Chain: D: PDB Molecule:small gtp-binding protein-like;
PDBTitle: ara7-gdp/atvps9a(d185n)
79c2yz2B_



not modelled 92.0 33 PDB header:hydrolase
Chain: B: PDB Molecule:putative abc transporter atp-binding protein tm_0222;
PDBTitle: crystal structure of the abc transporter in the cobalt transport2 system
80c2fv8A_



not modelled 92.0 30 PDB header:signaling protein
Chain: A: PDB Molecule:rho-related gtp-binding protein rhob;
PDBTitle: the crystal structure of rhob in the gdp-bound state
81d1zj6a1



not modelled 91.9 18 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
82d1tada2



not modelled 91.9 22 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
83d1ds6a_



not modelled 91.9 25 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
84d1z07a1



not modelled 91.9 18 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
85c2bovA_



not modelled 91.9 36 PDB header:transferase
Chain: A: PDB Molecule:ras-related protein ral-a;
PDBTitle: molecular recognition of an adp-ribosylating clostridium2 botulinum c3 exoenzyme by rala gtpase
86d2erya1



not modelled 91.9 52 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
87c3eplA_



not modelled 91.9 35 PDB header:transferase/rna
Chain: A: PDB Molecule:trna isopentenyltransferase;
PDBTitle: crystallographic snapshots of eukaryotic2 dimethylallyltransferase acting on trna: insight into trna3 recognition and reaction mechanism
88d1in4a2



not modelled 91.9 18 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Extended AAA-ATPase domain
89d1xtqa1



not modelled 91.8 39 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
90d2qtvb1



not modelled 91.8 22 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
91d2a5da1



not modelled 91.8 22 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
92d1l7vc_



not modelled 91.8 22 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
93c3bwdD_



not modelled 91.8 32 PDB header:plant protein
Chain: D: PDB Molecule:rac-like gtp-binding protein arac6;
PDBTitle: crystal structure of the plant rho protein rop5
94c2pzfB_



not modelled 91.8 24 PDB header:hydrolase
Chain: B: PDB Molecule:cystic fibrosis transmembrane conductance regulator;
PDBTitle: minimal human cftr first nucleotide binding domain as a head-to-tail2 dimer with delta f508
95c2j3eA_



not modelled 91.8 41 PDB header:protein transport
Chain: A: PDB Molecule:t7i23.11 protein;
PDBTitle: dimerization is important for the gtpase activity of2 chloroplast translocon components attoc33 and pstoc159
96c2o52B_



not modelled 91.8 47 PDB header:protein transport
Chain: B: PDB Molecule:ras-related protein rab-4b;
PDBTitle: crystal structure of human rab4b in complex with gdp
97d1x1ra1



not modelled 91.7 48 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
98c2ze5A_



not modelled 91.7 22 PDB header:transferase
Chain: A: PDB Molecule:isopentenyl transferase;
PDBTitle: crystal structure of adenosine phosphate-isopentenyltransferase
99c3ch4B_



not modelled 91.7 21 PDB header:transferase
Chain: B: PDB Molecule:phosphomevalonate kinase;
PDBTitle: the crystal structure of human phosphomavelonate kinase at2 1.8 a resolution
100c3doeA_



not modelled 91.7 18 PDB header:signaling protein/hydrolase
Chain: A: PDB Molecule:adp-ribosylation factor-like protein 2;
PDBTitle: complex of arl2 and bart, crystal form 1
101d1yzga1



not modelled 91.7 21 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
102c2f7sA_



not modelled 91.7 19 PDB header:signaling protein
Chain: A: PDB Molecule:ras-related protein rab-27b;
PDBTitle: the crystal structure of human rab27b bound to gdp
103d2f7sa1



not modelled 91.7 19 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
104c1z06A_



not modelled 91.7 26 PDB header:protein transport
Chain: A: PDB Molecule:ras-related protein rab-33b;
PDBTitle: gppnhp-bound rab33 gtpase
105d1z06a1



not modelled 91.7 26 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
106d1r2qa_



not modelled 91.7 22 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
107c2xtnA_



not modelled 91.6 53 PDB header:immune system
Chain: A: PDB Molecule:gtpase imap family member 2;
PDBTitle: crystal structure of gtp-bound human gimap2, amino acid2 residues 1-234
108d2fv8a1



not modelled 91.6 30 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
109d1yzna1



not modelled 91.6 26 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
110c1gwnA_



not modelled 91.6 30 PDB header:gtpase
Chain: A: PDB Molecule:rho-related gtp-binding protein rhoe;
PDBTitle: the crystal structure of the core domain of rhoe/rnd3 - a2 constitutively activated small g protein
111d1m7ba_



not modelled 91.6 30 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
112c2ihyB_



not modelled 91.6 40 PDB header:hydrolase
Chain: B: PDB Molecule:abc transporter, atp-binding protein;
PDBTitle: structure of the staphylococcus aureus putative atpase subunit of an2 atp-binding cassette (abc) transporter
113d1moza_



not modelled 91.6 29 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
114c2xtpA_



not modelled 91.6 53 PDB header:immune system
Chain: A: PDB Molecule:gtpase imap family member 2;
PDBTitle: crystal structure of nucleotide-free human gimap2, amino2 acid residues 1-260
115d1np6a_



not modelled 91.5 21 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nitrogenase iron protein-like
116c3clvA_



not modelled 91.5 26 PDB header:signaling protein
Chain: A: PDB Molecule:rab5 protein, putative;
PDBTitle: crystal structure of rab5a from plasmodium falciparum,2 pfb0500c
117c2q6tB_



not modelled 91.5 12 PDB header:hydrolase
Chain: B: PDB Molecule:dnab replication fork helicase;
PDBTitle: crystal structure of the thermus aquaticus dnab monomer
118d2fn4a1



not modelled 91.5 48 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
119d1sxjd2



not modelled 91.5 18 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Extended AAA-ATPase domain
120c3regA_



not modelled 91.4 26 PDB header:signaling protein
Chain: A: PDB Molecule:rho-like small gtpase;
PDBTitle: crystal structure of ehrho1 bound to a gtp analog and magnesium

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0