Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP39831
DateThu Jan 5 12:00:56 GMT 2012
Unique Job IDe98644496c2dc7b7

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2cfcB_
Top template information
PDB header:oxidoreductase
Chain: B: PDB Molecule:2-(r)-hydroxypropyl-com dehydrogenase;
PDBTitle: structural basis for stereo selectivity in the (r)- and2 (s)-hydroxypropylethane thiosulfonate dehydrogenases
Confidence and coverage
Confidence:100.0% Coverage: 96%
238 residues ( 96% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MIVLVTGATAGFGECITRRFIQQGHKVIATGRRQERLQELKDELGDNLYIAQLDVRNRAA
Secondary structure 
SS confidence 
Disorder  ?
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  IEEMLASLPAEWCNIDILVNNAGLALGMEPAHKASVEDWETMIDTNNKGLVYMTRAVLPG
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  MVERNHGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLNLRTDLHGTAVRVTDIEPGLV
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  GGTEFSNVRFKGDDGKAEKTYQNTVALTPEDVSEAVWWVSTLPAHVNINTLEMMPVTQSY
Secondary structure 
SS confidence 
Disorder 
??????
???????
Disorder confidence 
 
   ........
Sequence  AGLNVHRQ
Secondary structure 
SS confidence 
Disorder 
???????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2cfc chain B

3D model

Region: 2 - 242
Aligned: 238
Modelled: 241
Confidence: 100.0%
Identity: 27%
PDB header:oxidoreductase
Chain: B: PDB Molecule:2-(r)-hydroxypropyl-com dehydrogenase;
PDBTitle: structural basis for stereo selectivity in the (r)- and2 (s)-hydroxypropylethane thiosulfonate dehydrogenases

Phyre2

PDB 3tox chain G

3D model

Region: 2 - 241
Aligned: 237
Modelled: 240
Confidence: 100.0%
Identity: 25%
PDB header:oxidoreductase
Chain: G: PDB Molecule:short chain dehydrogenase;
PDBTitle: crystal structure of a short chain dehydrogenase in complex with2 nad(p) from sinorhizobium meliloti 1021

Phyre2

PDB 1ae1 chain A

3D model

Region: 2 - 245
Aligned: 233
Modelled: 244
Confidence: 100.0%
Identity: 18%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2ae2 chain A

3D model

Region: 2 - 244
Aligned: 240
Modelled: 243
Confidence: 100.0%
Identity: 18%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 3svt chain A

3D model

Region: 2 - 241
Aligned: 237
Modelled: 240
Confidence: 100.0%
Identity: 22%
PDB header:oxidoreductase
Chain: A: PDB Molecule:short-chain type dehydrogenase/reductase;
PDBTitle: structure of a short-chain type dehydrogenase/reductase from2 mycobacterium ulcerans

Phyre2

PDB 1hdc chain A

3D model

Region: 2 - 245
Aligned: 239
Modelled: 244
Confidence: 100.0%
Identity: 26%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 3nug chain A

3D model

Region: 2 - 243
Aligned: 239
Modelled: 242
Confidence: 100.0%
Identity: 20%
PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-(acyl-carrier protein) reductase;
PDBTitle: crystal structure of wild type tetrameric pyridoxal 4-dehydrogenase2 from mesorhizobium loti

Phyre2

PDB 2zat chain C

3D model

Region: 2 - 243
Aligned: 239
Modelled: 242
Confidence: 100.0%
Identity: 25%
PDB header:oxidoreductase
Chain: C: PDB Molecule:dehydrogenase/reductase sdr family member 4;
PDBTitle: crystal structure of a mammalian reductase

Phyre2

PDB 1iy8 chain A

3D model

Region: 2 - 242
Aligned: 238
Modelled: 241
Confidence: 100.0%
Identity: 20%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 3lf2 chain B

3D model

Region: 2 - 244
Aligned: 240
Modelled: 243
Confidence: 100.0%
Identity: 18%
PDB header:oxidoreductase
Chain: B: PDB Molecule:short chain oxidoreductase q9hya2;
PDBTitle: nadph bound structure of the short chain oxidoreductase q9hya2 from2 pseudomonas aeruginosa pao1 containing an atypical catalytic center

Phyre2

PDB 3cxt chain A

3D model

Region: 2 - 243
Aligned: 233
Modelled: 242
Confidence: 100.0%
Identity: 24%
PDB header:oxidoreductase
Chain: A: PDB Molecule:dehydrogenase with different specificities;
PDBTitle: quaternary complex structure of gluconate 5-dehydrogenase from2 streptococcus suis type 2

Phyre2

PDB 1w6u chain A

3D model

Region: 2 - 247
Aligned: 239
Modelled: 246
Confidence: 100.0%
Identity: 14%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1gee chain A

3D model

Region: 2 - 247
Aligned: 243
Modelled: 246
Confidence: 100.0%
Identity: 18%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1k2w chain A

3D model

Region: 2 - 241
Aligned: 237
Modelled: 240
Confidence: 100.0%
Identity: 24%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 3ppi chain A

3D model

Region: 2 - 241
Aligned: 236
Modelled: 240
Confidence: 100.0%
Identity: 19%
PDB header:oxidoreductase
Chain: A: PDB Molecule:3-hydroxyacyl-coa dehydrogenase type-2;
PDBTitle: crystal structure of 3-hydroxyacyl-coa dehydrogenase type-2 from2 mycobacterium avium

Phyre2

PDB 3rku chain C

3D model

Region: 2 - 247
Aligned: 242
Modelled: 245
Confidence: 100.0%
Identity: 36%
PDB header:oxidoreductase
Chain: C: PDB Molecule:oxidoreductase ymr226c;
PDBTitle: substrate fingerprint and the structure of nadp+ dependent serine2 dehydrogenase from saccharomyces cerevisiae complexed with nadp+

Phyre2

PDB 3ak4 chain C

3D model

Region: 2 - 241
Aligned: 237
Modelled: 240
Confidence: 100.0%
Identity: 19%
PDB header:oxidoreductase
Chain: C: PDB Molecule:nadh-dependent quinuclidinone reductase;
PDBTitle: crystal structure of nadh-dependent quinuclidinone reductase from2 agrobacterium tumefaciens

Phyre2

PDB 1zem chain A domain 1

3D model

Region: 2 - 239
Aligned: 235
Modelled: 235
Confidence: 100.0%
Identity: 22%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1fmc chain A

3D model

Region: 2 - 242
Aligned: 236
Modelled: 241
Confidence: 100.0%
Identity: 22%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 3k31 chain B

3D model

Region: 2 - 248
Aligned: 238
Modelled: 247
Confidence: 100.0%
Identity: 16%
PDB header:oxidoreductase
Chain: B: PDB Molecule:enoyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of eonyl-(acyl-carrier-protein) reductase from2 anaplasma phagocytophilum in complex with nad at 1.9a resolution

Phyre2
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c2cfcB_
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c3toxG_
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d1ae1a_
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d2ae2a_
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c3svtA_
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d1hdca_
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c3nugA_
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c2zatC_
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d1iy8a_
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c3lf2B_
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c3cxtA_
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d1w6ua_
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d1geea_
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d1k2wa_
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c3ppiA_
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c3rkuC_
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c3ak4C_
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d1zema1
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d1fmca_
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c3k31B_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2cfcB_
100.0 27 PDB header:oxidoreductase
Chain: B: PDB Molecule:2-(r)-hydroxypropyl-com dehydrogenase;
PDBTitle: structural basis for stereo selectivity in the (r)- and2 (s)-hydroxypropylethane thiosulfonate dehydrogenases
2c3toxG_
100.0 25 PDB header:oxidoreductase
Chain: G: PDB Molecule:short chain dehydrogenase;
PDBTitle: crystal structure of a short chain dehydrogenase in complex with2 nad(p) from sinorhizobium meliloti 1021
3d1ae1a_
100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
4d2ae2a_
100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
5c3svtA_
100.0 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:short-chain type dehydrogenase/reductase;
PDBTitle: structure of a short-chain type dehydrogenase/reductase from2 mycobacterium ulcerans
6d1hdca_
100.0 26 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
7c3nugA_
100.0 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-(acyl-carrier protein) reductase;
PDBTitle: crystal structure of wild type tetrameric pyridoxal 4-dehydrogenase2 from mesorhizobium loti
8c2zatC_
100.0 25 PDB header:oxidoreductase
Chain: C: PDB Molecule:dehydrogenase/reductase sdr family member 4;
PDBTitle: crystal structure of a mammalian reductase
9d1iy8a_
100.0 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
10c3lf2B_
100.0 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:short chain oxidoreductase q9hya2;
PDBTitle: nadph bound structure of the short chain oxidoreductase q9hya2 from2 pseudomonas aeruginosa pao1 containing an atypical catalytic center
11c3cxtA_
100.0 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:dehydrogenase with different specificities;
PDBTitle: quaternary complex structure of gluconate 5-dehydrogenase from2 streptococcus suis type 2
12d1w6ua_
100.0 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
13d1geea_
100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
14d1k2wa_
100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
15c3ppiA_
100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-hydroxyacyl-coa dehydrogenase type-2;
PDBTitle: crystal structure of 3-hydroxyacyl-coa dehydrogenase type-2 from2 mycobacterium avium
16c3rkuC_
100.0 36 PDB header:oxidoreductase
Chain: C: PDB Molecule:oxidoreductase ymr226c;
PDBTitle: substrate fingerprint and the structure of nadp+ dependent serine2 dehydrogenase from saccharomyces cerevisiae complexed with nadp+
17c3ak4C_
100.0 19 PDB header:oxidoreductase
Chain: C: PDB Molecule:nadh-dependent quinuclidinone reductase;
PDBTitle: crystal structure of nadh-dependent quinuclidinone reductase from2 agrobacterium tumefaciens
18d1zema1
100.0 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
19d1fmca_
100.0 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
20c3k31B_
100.0 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:enoyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of eonyl-(acyl-carrier-protein) reductase from2 anaplasma phagocytophilum in complex with nad at 1.9a resolution
21d1xhla_
not modelled 100.0 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
22d1yxma1
not modelled 100.0 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
23c3gk3D_
not modelled 100.0 24 PDB header:oxidoreductase
Chain: D: PDB Molecule:acetoacetyl-coa reductase;
PDBTitle: crystal structure of acetoacetyl-coa reductase from2 burkholderia pseudomallei 1710b
24d2rhca1
not modelled 100.0 28 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
25c3rihB_
not modelled 100.0 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:short chain dehydrogenase or reductase;
PDBTitle: crystal structure of a putative short chain dehydrogenase or reductase2 from mycobacterium abscessus
26c3gvcB_
not modelled 100.0 23 PDB header:oxidoreductase
Chain: B: PDB Molecule:probable short-chain type
PDBTitle: crystal structure of probable short-chain dehydrogenase-2 reductase from mycobacterium tuberculosis
27c3grkE_
not modelled 100.0 17 PDB header:oxidoreductase
Chain: E: PDB Molecule:enoyl-(acyl-carrier-protein) reductase (nadh);
PDBTitle: crystal structure of short chain dehydrogenase reductase2 sdr glucose-ribitol dehydrogenase from brucella melitensis
28c1w4zA_
not modelled 100.0 28 PDB header:antibiotic biosynthesis
Chain: A: PDB Molecule:ketoacyl reductase;
PDBTitle: structure of actinorhodin polyketide (actiii) reductase
29c3sjuA_
not modelled 100.0 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:keto reductase;
PDBTitle: hedamycin polyketide ketoreductase bound to nadph
30d1gega_
not modelled 100.0 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
31d2pd4a1
not modelled 100.0 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
32c3ijrF_
not modelled 100.0 17 PDB header:oxidoreductase
Chain: F: PDB Molecule:oxidoreductase, short chain dehydrogenase/reductase family;
PDBTitle: 2.05 angstrom resolution crystal structure of a short chain2 dehydrogenase from bacillus anthracis str. 'ames ancestor' in complex3 with nad+
33d1pr9a_
not modelled 100.0 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
34d1nffa_
not modelled 100.0 26 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
35d1zk4a1
not modelled 100.0 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
36c3pk0B_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: B: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: crystal structure of short-chain dehydrogenase/reductase sdr from2 mycobacterium smegmatis
37c2c07A_
not modelled 100.0 27 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-(acyl-carrier protein) reductase;
PDBTitle: oxoacyl-acp reductase of plasmodium falciparum
38d2c07a1
not modelled 100.0 27 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
39c3t7cC_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: C: PDB Molecule:carveol dehydrogenase;
PDBTitle: crystal structure of carveol dehydrogenase from mycobacterium avium2 bound to nad
40c2q2qG_
not modelled 100.0 26 PDB header:oxidoreductase
Chain: G: PDB Molecule:beta-d-hydroxybutyrate dehydrogenase;
PDBTitle: structure of d-3-hydroxybutyrate dehydrogenase from pseudomonas putida
41d2bgka1
not modelled 100.0 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
42d1bdba_
not modelled 100.0 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
43c3iccA_
not modelled 100.0 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative 3-oxoacyl-(acyl carrier protein) reductase;
PDBTitle: crystal structure of a putative 3-oxoacyl-(acyl carrier protein)2 reductase from bacillus anthracis at 1.87 a resolution
44d1ydea1
not modelled 100.0 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
45d1edoa_
not modelled 100.0 26 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
46c2nwqA_
not modelled 100.0 53 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable short-chain dehydrogenase;
PDBTitle: short chain dehydrogenase from pseudomonas aeruginosa
47d1xkqa_
not modelled 100.0 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
48c3imfA_
not modelled 100.0 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:short chain dehydrogenase;
PDBTitle: 1.99 angstrom resolution crystal structure of a short chain2 dehydrogenase from bacillus anthracis str. 'ames ancestor'
49c3emkA_
not modelled 100.0 32 PDB header:oxidoreductase
Chain: A: PDB Molecule:glucose/ribitol dehydrogenase;
PDBTitle: 2.5a crystal structure of glucose/ribitol dehydrogenase2 from brucella melitensis
50d1q7ba_
not modelled 100.0 29 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
51c3ai3A_
not modelled 100.0 25 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadph-sorbose reductase;
PDBTitle: the crystal structure of l-sorbose reductase from gluconobacter2 frateurii complexed with nadph and l-sorbose
52c2jjyD_
not modelled 100.0 14 PDB header:oxidoreductase
Chain: D: PDB Molecule:enoyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of francisella tularensis enoyl reductase2 (ftfabi) with bound nad
53d1hxha_
not modelled 100.0 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
54d1o5ia_
not modelled 100.0 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
55d1e6wa_
not modelled 100.0 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
56c2jahB_
not modelled 100.0 29 PDB header:oxidoreductase
Chain: B: PDB Molecule:clavulanic acid dehydrogenase;
PDBTitle: biochemical and structural analysis of the clavulanic acid2 dehydeogenase (cad) from streptomyces clavuligerus
57c2pd6D_
not modelled 100.0 22 PDB header:oxidoreductase
Chain: D: PDB Molecule:estradiol 17-beta-dehydrogenase 8;
PDBTitle: structure of human hydroxysteroid dehydrogenase type 8, hsd17b8
58c3lylB_
not modelled 100.0 25 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-oxoacyl-(acyl-carrier-protein) reductase;
PDBTitle: structure of 3-oxoacyl-acylcarrier protein reductase, fabg2 from francisella tularensis
59c3uf0A_
not modelled 100.0 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: crystal structure of a putative nad(p) dependent gluconate 5-2 dehydrogenase from beutenbergia cavernae(efi target efi-502044) with3 bound nadp (low occupancy)
60c3itdA_
not modelled 100.0 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:17beta-hydroxysteroid dehydrogenase;
PDBTitle: crystal structure of an inactive 17beta-hydroxysteroid dehydrogenase2 (y167f mutated form) from fungus cochliobolus lunatus
61c3o38D_
not modelled 100.0 23 PDB header:oxidoreductase
Chain: D: PDB Molecule:short chain dehydrogenase;
PDBTitle: crystal structure of a short chain dehydrogenase from mycobacterium2 smegmatis
62c3pgxB_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: B: PDB Molecule:carveol dehydrogenase;
PDBTitle: crystal structure of a putative carveol dehydrogenase from2 mycobacterium paratuberculosis bound to nicotinamide adenine3 dinucleotide
63c3gr6A_
not modelled 100.0 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:enoyl-[acyl-carrier-protein] reductase [nadh];
PDBTitle: crystal structure of the staphylococcus aureus enoyl-acyl2 carrier protein reductase (fabi) in complex with nadp and3 triclosan
64c3afnC_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: C: PDB Molecule:carbonyl reductase;
PDBTitle: crystal structure of aldose reductase a1-r complexed with nadp
65c3ezlA_
not modelled 100.0 28 PDB header:oxidoreductase
Chain: A: PDB Molecule:acetoacetyl-coa reductase;
PDBTitle: crystal structure of acetyacetyl-coa reductase from2 burkholderia pseudomallei 1710b
66d1qsga_
not modelled 100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
67c3osuA_
not modelled 100.0 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of the 3-oxoacyl-acyl carrier protein reductase,2 fabg, from staphylococcus aureus
68c2uvdE_
not modelled 100.0 28 PDB header:oxidoreductase
Chain: E: PDB Molecule:3-oxoacyl-(acyl-carrier-protein) reductase;
PDBTitle: the crystal structure of a 3-oxoacyl-(acyl carrier protein)2 reductase from bacillus anthracis (ba3989)
69c3v2gA_
not modelled 100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of a dehydrogenase/reductase from sinorhizobium2 meliloti 1021
70c3i4fD_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: D: PDB Molecule:3-oxoacyl-[acyl-carrier protein] reductase;
PDBTitle: structure of putative 3-oxoacyl-reductase from bacillus thuringiensis
71c3oidA_
not modelled 100.0 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:enoyl-[acyl-carrier-protein] reductase [nadph];
PDBTitle: crystal structure of enoyl-acp reductases iii (fabl) from b. subtilis2 (complex with nadp and tcl)
72c2ph3B_
not modelled 100.0 22 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-oxoacyl-[acyl carrier protein] reductase;
PDBTitle: crystal structure of 3-oxoacyl-[acyl carrier protein] reductase2 ttha0415 from thermus thermophilus
73c3r3sD_
not modelled 100.0 17 PDB header:oxidoreductase
Chain: D: PDB Molecule:oxidoreductase;
PDBTitle: structure of the ygha oxidoreductase from salmonella enterica
74d1h5qa_
not modelled 100.0 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
75d1ja9a_
not modelled 100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
76c2p68A_
not modelled 100.0 26 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of aq_1716 from aquifex aeolicus vf5
77c3bmrA_
not modelled 100.0 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:pteridine reductase;
PDBTitle: structure of pteridine reductase 1 (ptr1) from trypanosoma2 brucei in ternary complex with cofactor (nadp+) and3 inhibitor (compound ax6)
78d1g0oa_
not modelled 100.0 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
79c3ek2D_
not modelled 100.0 18 PDB header:oxidoreductase
Chain: D: PDB Molecule:enoyl-(acyl-carrier-protein) reductase (nadh);
PDBTitle: crystal structure of eonyl-(acyl carrier protein) reductase2 from burkholderia pseudomallei 1719b
80d1mxha_
not modelled 100.0 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
81c3oecA_
not modelled 100.0 25 PDB header:oxidoreductase
Chain: A: PDB Molecule:carveol dehydrogenase (mytha.01326.c, a0r518 homolog);
PDBTitle: crystal structure of carveol dehydrogenase from mycobacterium2 thermoresistibile
82d1ulua_
not modelled 100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
83c3ftpD_
not modelled 100.0 27 PDB header:oxidoreductase
Chain: D: PDB Molecule:3-oxoacyl-[acyl-carrier protein] reductase;
PDBTitle: crystal structure of 3-ketoacyl-(acyl-carrier-protein)2 reductase from burkholderia pseudomallei at 2.05 a3 resolution
84d2d1ya1
not modelled 100.0 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
85d1x1ta1
not modelled 100.0 26 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
86d2ew8a1
not modelled 100.0 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
87c3v2hB_
not modelled 100.0 23 PDB header:oxidoreductase
Chain: B: PDB Molecule:d-beta-hydroxybutyrate dehydrogenase;
PDBTitle: the crystal structure of d-beta-hydroxybutyrate dehydrogenase from2 sinorhizobium meliloti
88c3uveC_
not modelled 100.0 26 PDB header:oxidoreductase
Chain: C: PDB Molecule:carveol dehydrogenase ((+)-trans-carveol dehydrogenase);
PDBTitle: crystal structure of carveol dehydrogenase ((+)-trans-carveol2 dehydrogenase) from mycobacterium avium
89c3llsB_
not modelled 100.0 19 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-ketoacyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase from2 mycobacterium tuberculosis
90c2p91A_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:enoyl-[acyl-carrier-protein] reductase [nadh];
PDBTitle: crystal structure of enoyl-[acyl-carrier-protein] reductase (nadh)2 from aquifex aeolicus vf5
91d1vl8a_
not modelled 100.0 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
92c2qioA_
not modelled 100.0 18 PDB header:unknown function
Chain: A: PDB Molecule:enoyl-(acyl-carrier-protein) reductase;
PDBTitle: x-ray structure of enoyl-acyl carrier protein reductase from bacillus2 anthracis with triclosan
93c2z1nA_
not modelled 100.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:dehydrogenase;
PDBTitle: crystal structure of ape0912 from aeropyrum pernix k1
94c2qhxB_
not modelled 100.0 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:pteridine reductase 1;
PDBTitle: structure of pteridine reductase from leishmania major2 complexed with a ligand
95c3diiB_
not modelled 100.0 24 PDB header:oxidoreductase
Chain: B: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: crystal structure of a carbohydrate specific scor enzyme2 from clostridium thermocellum, ligand-free form
96c2et6A_
not modelled 100.0 26 PDB header:oxidoreductase
Chain: A: PDB Molecule:(3r)-hydroxyacyl-coa dehydrogenase;
PDBTitle: (3r)-hydroxyacyl-coa dehydrogenase domain of candida tropicalis2 peroxisomal multifunctional enzyme type 2
97d1ulsa_
not modelled 100.0 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
98c2b4qB_
not modelled 100.0 22 PDB header:oxidoreductase
Chain: B: PDB Molecule:rhamnolipids biosynthesis 3-oxoacyl-[acyl-
PDBTitle: pseudomonas aeruginosa rhlg/nadp active-site complex
99c3sx2F_
not modelled 100.0 24 PDB header:oxidoreductase
Chain: F: PDB Molecule:putative 3-ketoacyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of a putative 3-ketoacyl-(acyl-carrier-protein)2 reductase from mycobacterium paratuberculosis in complex with nad
100c3gdfA_
not modelled 100.0 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable nadp-dependent mannitol dehydrogenase;
PDBTitle: crystal structure of the nadp-dependent mannitol dehydrogenase from2 cladosporium herbarum.
101d1uaya_
not modelled 100.0 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
102c3r1iB_
not modelled 100.0 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:short-chain type dehydrogenase/reductase;
PDBTitle: crystal structure of a short-chain type dehydrogenase/reductase from2 mycobacterium marinum
103c3n74A_
not modelled 100.0 27 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-ketoacyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase from2 brucella melitensis
104d1p33a_
not modelled 100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
105c3uxyC_
not modelled 100.0 23 PDB header:oxidoreductase
Chain: C: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: the crystal structure of short chain dehydrogenase from rhodobacter2 sphaeroides
106d2a4ka1
not modelled 100.0 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
107d1spxa_
not modelled 100.0 26 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
108c3rkrC_
not modelled 100.0 32 PDB header:oxidoreductase
Chain: C: PDB Molecule:short chain oxidoreductase;
PDBTitle: crystal structure of a metagenomic short-chain oxidoreductase (sdr) in2 complex with nadp
109d1cyda_
not modelled 100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
110d1uh5a_
not modelled 100.0 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
111d2o23a1
not modelled 100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
112c3tl3A_
not modelled 100.0 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:short-chain type dehydrogenase/reductase;
PDBTitle: structure of a short-chain type dehydrogenase/reductase from2 mycobacterium ulcerans
113c3i1jB_
not modelled 100.0 24 PDB header:oxidoreductase
Chain: B: PDB Molecule:oxidoreductase, short chain
PDBTitle: structure of a putative short chain dehydrogenase from2 pseudomonas syringae
114c3sc4A_
not modelled 100.0 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:short chain dehydrogenase (a0qtm2 homolog);
PDBTitle: crystal structure of a short chain dehydrogenase (a0qtm2 homolog)2 mycobacterium thermoresistibile
115d2bd0a1
not modelled 100.0 25 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
116d1zbqa1
not modelled 100.0 26 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
117c1zbqB_
not modelled 100.0 26 PDB header:oxidoreductase
Chain: B: PDB Molecule:17-beta-hydroxysteroid dehydrogenase 4;
PDBTitle: crystal structure of human 17-beta-hydroxysteroid dehydrogenase type 42 in complex with nad
118c2wdzD_
not modelled 100.0 18 PDB header:oxidoreductase
Chain: D: PDB Molecule:short-chain dehydrogenase/reductase;
PDBTitle: crystal structure of the short chain dehydrogenase2 galactitol-dehydrogenase (gatdh) of rhodobacter3 sphaeroides in complex with nad+ and 1,2-pentandiol
119d1oaaa_
not modelled 100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
120c2dteB_
not modelled 100.0 22 PDB header:oxidoreductase
Chain: B: PDB Molecule:glucose 1-dehydrogenase related protein;
PDBTitle: structure of thermoplasma acidophilum aldohexose dehydrogenase (aldt)2 in complex with nadh

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0