Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0A988
DateThu Jan 5 11:09:37 GMT 2012
Unique Job IDe8f7ff2987c0a147

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1unnA_
Top template information
PDB header:beta-clamp
Chain: A: PDB Molecule:dna polymerase iii beta subunit;
PDBTitle: complex of beta-clamp processivity factor and little finger2 domain of poliv
Confidence and coverage
Confidence:100.0% Coverage:100%
366 residues (100% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV
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Disorder  ?



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??

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   .........70.........80.........90.........100.........110.........120
Sequence  QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD
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   .........130.........140.........150.........160.........170.........180
Sequence  DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC
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Disorder 


??






















































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   .........190.........200.........210.........220.........230.........240
Sequence  SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR
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????




















































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   .........250.........260.........270.........280.........290.........300
Sequence  FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE
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????
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   .........310.........320.........330.........340.........350.........360
Sequence  EAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYV
Secondary structure 
















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   ......
Sequence  VMPMRL
Secondary structure 
SS confidence 





Disorder 
?????
Disorder confidence 





 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1unn chain A

3D model

Region: 1 - 366
Aligned: 366
Modelled: 366
Confidence: 100.0%
Identity: 100%
PDB header:beta-clamp
Chain: A: PDB Molecule:dna polymerase iii beta subunit;
PDBTitle: complex of beta-clamp processivity factor and little finger2 domain of poliv

Phyre2

PDB 1vpk chain A

3D model

Region: 1 - 366
Aligned: 364
Modelled: 366
Confidence: 100.0%
Identity: 27%
PDB header:transferase
Chain: A: PDB Molecule:dna polymerase iii, beta subunit;
PDBTitle: crystal structure of dna polymerase iii, beta subunit (tm0262) from2 thermotoga maritima at 2.00 a resolution

Phyre2

PDB 2awa chain B

3D model

Region: 1 - 365
Aligned: 364
Modelled: 365
Confidence: 100.0%
Identity: 22%
PDB header:transferase
Chain: B: PDB Molecule:dna polymerase iii, beta chain;
PDBTitle: crystal structure of dna polymerase iii, beta chain (ec 2.7.7.7)2 (np_344555.1) from streptococcus pneumoniae tigr4 at 2.50 a3 resolution

Phyre2

PDB 3p16 chain A

3D model

Region: 1 - 366
Aligned: 361
Modelled: 366
Confidence: 100.0%
Identity: 30%
PDB header:transferase
Chain: A: PDB Molecule:dna polymerase iii subunit beta;
PDBTitle: crystal structure of dna polymerase iii sliding clamp

Phyre2

PDB 3t0p chain B

3D model

Region: 1 - 366
Aligned: 364
Modelled: 365
Confidence: 100.0%
Identity: 23%
PDB header:transferase
Chain: B: PDB Molecule:dna polymerase iii, beta subunit;
PDBTitle: crystal structure of a putative dna polymerase iii beta subunit2 (eubrec_0002; ere_29750) from eubacterium rectale atcc 33656 at 2.263 a resolution

Phyre2

PDB 1ok7 chain A domain 3

3D model

Region: 245 - 366
Aligned: 122
Modelled: 122
Confidence: 100.0%
Identity: 100%
Fold: DNA clamp
Superfamily: DNA clamp
Family: DNA polymerase III, beta subunit

Phyre2

PDB 1vpk chain A domain 3

3D model

Region: 245 - 366
Aligned: 122
Modelled: 122
Confidence: 100.0%
Identity: 25%
Fold: DNA clamp
Superfamily: DNA clamp
Family: DNA polymerase III, beta subunit

Phyre2

PDB 1rwz chain A

3D model

Region: 126 - 363
Aligned: 223
Modelled: 238
Confidence: 100.0%
Identity: 14%
PDB header:replication
Chain: A: PDB Molecule:dna polymerase sliding clamp;
PDBTitle: crystal structure of proliferating cell nuclear antigen (pcna) from a.2 fulgidus

Phyre2

PDB 3hi8 chain C

3D model

Region: 129 - 363
Aligned: 221
Modelled: 235
Confidence: 100.0%
Identity: 15%
PDB header:replication
Chain: C: PDB Molecule:proliferating cell nuclear antigen pcna;
PDBTitle: crystal structure of proliferating cell nuclear antigen2 (pcna) from haloferax volcanii

Phyre2

PDB 2ix2 chain B

3D model

Region: 131 - 363
Aligned: 217
Modelled: 224
Confidence: 100.0%
Identity: 12%
PDB header:replication
Chain: B: PDB Molecule:dna polymerase sliding clamp c;
PDBTitle: crystal structure of the heterotrimeric pcna from2 sulfolobus solfataricus

Phyre2

PDB 3p91 chain A

3D model

Region: 131 - 363
Aligned: 219
Modelled: 233
Confidence: 100.0%
Identity: 12%
PDB header:dna binding protein
Chain: A: PDB Molecule:proliferating cell nuclear antigen;
PDBTitle: crystal structure of proliferating cellular nuclear antigen from2 entamoeba histolytica

Phyre2

PDB 2zvw chain H

3D model

Region: 131 - 363
Aligned: 222
Modelled: 233
Confidence: 100.0%
Identity: 15%
PDB header:dna binding protein
Chain: H: PDB Molecule:proliferating cell nuclear antigen 2;
PDBTitle: crystal structure of proliferating cell nuclear antigen 22 and short peptide from human p21

Phyre2

PDB 1ok7 chain A domain 1

3D model

Region: 1 - 122
Aligned: 122
Modelled: 122
Confidence: 100.0%
Identity: 100%
Fold: DNA clamp
Superfamily: DNA clamp
Family: DNA polymerase III, beta subunit

Phyre2

PDB 1ok7 chain A domain 2

3D model

Region: 123 - 244
Aligned: 122
Modelled: 122
Confidence: 100.0%
Identity: 100%
Fold: DNA clamp
Superfamily: DNA clamp
Family: DNA polymerase III, beta subunit

Phyre2

PDB 1vpk chain A domain 2

3D model

Region: 123 - 244
Aligned: 121
Modelled: 122
Confidence: 100.0%
Identity: 26%
Fold: DNA clamp
Superfamily: DNA clamp
Family: DNA polymerase III, beta subunit

Phyre2

PDB 3aiz chain D

3D model

Region: 131 - 363
Aligned: 218
Modelled: 233
Confidence: 100.0%
Identity: 12%
PDB header:replication
Chain: D: PDB Molecule:dna polymerase sliding clamp c;
PDBTitle: crystal structure of pcna2-pcna3 complex from sulfolobus tokodaii2 (p21212)

Phyre2

PDB 1ge8 chain A

3D model

Region: 131 - 363
Aligned: 212
Modelled: 233
Confidence: 100.0%
Identity: 18%
PDB header:dna binding protein
Chain: A: PDB Molecule:proliferation cell nuclear antigen;
PDBTitle: proliferating cell nuclear antigen (pcna) homolog from2 pyrococcus furiosus

Phyre2

PDB 2zvk chain C

3D model

Region: 131 - 363
Aligned: 216
Modelled: 233
Confidence: 100.0%
Identity: 12%
PDB header:transferase
Chain: C: PDB Molecule:proliferating cell nuclear antigen;
PDBTitle: crystal structure of pcna in complex with dna polymerase eta fragment

Phyre2

PDB 1vpk chain A domain 1

3D model

Region: 1 - 121
Aligned: 120
Modelled: 121
Confidence: 100.0%
Identity: 29%
Fold: DNA clamp
Superfamily: DNA clamp
Family: DNA polymerase III, beta subunit

Phyre2

PDB 3lx2 chain A

3D model

Region: 131 - 363
Aligned: 218
Modelled: 233
Confidence: 100.0%
Identity: 15%
PDB header:dna binding protein
Chain: A: PDB Molecule:dna polymerase sliding clamp 2;
PDBTitle: crystal structure analysis of pcna from thermococcus kodakaraensis2 tk0582

Phyre2
1

c1unnA_
2

c1vpkA_
3

c2awaB_
4

c3p16A_
5

c3t0pB_
6

d1ok7a3
7

d1vpka3
8

c1rwzA_
9

c3hi8C_
10

c2ix2B_
11

c3p91A_
12

c2zvwH_
13

d1ok7a1
14

d1ok7a2
15

d1vpka2
16

c3aizD_
17

c1ge8A_
18

c2zvkC_
19

d1vpka1
20

c3lx2A_
21



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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1unnA_



100.0 100 PDB header:beta-clamp
Chain: A: PDB Molecule:dna polymerase iii beta subunit;
PDBTitle: complex of beta-clamp processivity factor and little finger2 domain of poliv
2c1vpkA_



100.0 27 PDB header:transferase
Chain: A: PDB Molecule:dna polymerase iii, beta subunit;
PDBTitle: crystal structure of dna polymerase iii, beta subunit (tm0262) from2 thermotoga maritima at 2.00 a resolution
3c2awaB_



100.0 22 PDB header:transferase
Chain: B: PDB Molecule:dna polymerase iii, beta chain;
PDBTitle: crystal structure of dna polymerase iii, beta chain (ec 2.7.7.7)2 (np_344555.1) from streptococcus pneumoniae tigr4 at 2.50 a3 resolution
4c3p16A_



100.0 30 PDB header:transferase
Chain: A: PDB Molecule:dna polymerase iii subunit beta;
PDBTitle: crystal structure of dna polymerase iii sliding clamp
5c3t0pB_



100.0 23 PDB header:transferase
Chain: B: PDB Molecule:dna polymerase iii, beta subunit;
PDBTitle: crystal structure of a putative dna polymerase iii beta subunit2 (eubrec_0002; ere_29750) from eubacterium rectale atcc 33656 at 2.263 a resolution
6d1ok7a3



100.0 100 Fold:DNA clamp
Superfamily:DNA clamp
Family:DNA polymerase III, beta subunit
7d1vpka3



100.0 25 Fold:DNA clamp
Superfamily:DNA clamp
Family:DNA polymerase III, beta subunit
8c1rwzA_



100.0 14 PDB header:replication
Chain: A: PDB Molecule:dna polymerase sliding clamp;
PDBTitle: crystal structure of proliferating cell nuclear antigen (pcna) from a.2 fulgidus
9c3hi8C_



100.0 15 PDB header:replication
Chain: C: PDB Molecule:proliferating cell nuclear antigen pcna;
PDBTitle: crystal structure of proliferating cell nuclear antigen2 (pcna) from haloferax volcanii
10c2ix2B_



100.0 12 PDB header:replication
Chain: B: PDB Molecule:dna polymerase sliding clamp c;
PDBTitle: crystal structure of the heterotrimeric pcna from2 sulfolobus solfataricus
11c3p91A_



100.0 12 PDB header:dna binding protein
Chain: A: PDB Molecule:proliferating cell nuclear antigen;
PDBTitle: crystal structure of proliferating cellular nuclear antigen from2 entamoeba histolytica
12c2zvwH_



100.0 15 PDB header:dna binding protein
Chain: H: PDB Molecule:proliferating cell nuclear antigen 2;
PDBTitle: crystal structure of proliferating cell nuclear antigen 22 and short peptide from human p21
13d1ok7a1



100.0 100 Fold:DNA clamp
Superfamily:DNA clamp
Family:DNA polymerase III, beta subunit
14d1ok7a2



100.0 100 Fold:DNA clamp
Superfamily:DNA clamp
Family:DNA polymerase III, beta subunit
15d1vpka2



100.0 26 Fold:DNA clamp
Superfamily:DNA clamp
Family:DNA polymerase III, beta subunit
16c3aizD_



100.0 12 PDB header:replication
Chain: D: PDB Molecule:dna polymerase sliding clamp c;
PDBTitle: crystal structure of pcna2-pcna3 complex from sulfolobus tokodaii2 (p21212)
17c1ge8A_



100.0 18 PDB header:dna binding protein
Chain: A: PDB Molecule:proliferation cell nuclear antigen;
PDBTitle: proliferating cell nuclear antigen (pcna) homolog from2 pyrococcus furiosus
18c2zvkC_



100.0 12 PDB header:transferase
Chain: C: PDB Molecule:proliferating cell nuclear antigen;
PDBTitle: crystal structure of pcna in complex with dna polymerase eta fragment
19d1vpka1



100.0 29 Fold:DNA clamp
Superfamily:DNA clamp
Family:DNA polymerase III, beta subunit
20c3lx2A_



100.0 15 PDB header:dna binding protein
Chain: A: PDB Molecule:dna polymerase sliding clamp 2;
PDBTitle: crystal structure analysis of pcna from thermococcus kodakaraensis2 tk0582
21c2ijxA_



not modelled 100.0 14 PDB header:dna binding protein
Chain: A: PDB Molecule:dna polymerase sliding clamp a;
PDBTitle: crystal structure of pcna3 monomer from sulfolobus solfataricus.
22c2od8A_



not modelled 99.9 14 PDB header:protein binding
Chain: A: PDB Molecule:proliferating cell nuclear antigen;
PDBTitle: structure of a peptide derived from cdc9 bound to pcna
23c3k4xA_



not modelled 99.8 17 PDB header:dna binding protein/dna
Chain: A: PDB Molecule:proliferating cell nuclear antigen;
PDBTitle: eukaryotic sliding clamp pcna bound to dna
24c1ud9C_



not modelled 99.8 16 PDB header:dna binding protein
Chain: C: PDB Molecule:dna polymerase sliding clamp a;
PDBTitle: crystal structure of proliferating cell nuclear antigen (pcna) homolog2 from sulfolobus tokodaii
25c3aizB_



not modelled 99.7 9 PDB header:replication
Chain: B: PDB Molecule:dna polymerase sliding clamp b;
PDBTitle: crystal structure of pcna2-pcna3 complex from sulfolobus tokodaii2 (p21212)
26c3g65A_



not modelled 99.5 11 PDB header:cell cycle
Chain: A: PDB Molecule:cell cycle checkpoint control protein rad9a;
PDBTitle: crystal structure of the human rad9-rad1-hus1 dna damage2 checkpoint complex
27c1sxjF_



not modelled 99.4 16 PDB header:replication
Chain: F: PDB Molecule:proliferating cell nuclear antigen;
PDBTitle: crystal structure of the eukaryotic clamp loader2 (replication factor c, rfc) bound to the dna sliding clamp3 (proliferating cell nuclear antigen, pcna)
28c2ix2A_



not modelled 99.1 12 PDB header:replication
Chain: A: PDB Molecule:dna polymerase sliding clamp b;
PDBTitle: crystal structure of the heterotrimeric pcna from2 sulfolobus solfataricus
29c3g65B_



not modelled 98.9 10 PDB header:cell cycle
Chain: B: PDB Molecule:cell cycle checkpoint protein rad1;
PDBTitle: crystal structure of the human rad9-rad1-hus1 dna damage2 checkpoint complex
30c3ggrA_



not modelled 98.8 12 PDB header:cell cycle
Chain: A: PDB Molecule:cell cycle checkpoint control protein rad9a;
PDBTitle: crystal structure of the human rad9-hus1-rad1 complex
31d1u7ba2



not modelled 98.6 14 Fold:DNA clamp
Superfamily:DNA clamp
Family:DNA polymerase processivity factor
32d1iz5a2



not modelled 98.5 22 Fold:DNA clamp
Superfamily:DNA clamp
Family:DNA polymerase processivity factor
33d1plqa2



not modelled 98.5 16 Fold:DNA clamp
Superfamily:DNA clamp
Family:DNA polymerase processivity factor
34d1rwza2



not modelled 98.4 17 Fold:DNA clamp
Superfamily:DNA clamp
Family:DNA polymerase processivity factor
35d1ud9a2



not modelled 98.1 19 Fold:DNA clamp
Superfamily:DNA clamp
Family:DNA polymerase processivity factor
36c3l0wA_



not modelled 97.9 13 PDB header:replication
Chain: A: PDB Molecule:proliferating cell nuclear antigen;
PDBTitle: structure of split monoubiquitinated pcna with ubiquitin in2 position two
37d1rwza1



not modelled 97.6 12 Fold:DNA clamp
Superfamily:DNA clamp
Family:DNA polymerase processivity factor
38d1iz5a1



not modelled 97.5 11 Fold:DNA clamp
Superfamily:DNA clamp
Family:DNA polymerase processivity factor
39c1b8hA_



not modelled 96.8 9 PDB header:transferase
Chain: A: PDB Molecule:dna polymerase processivity component;
PDBTitle: sliding clamp, dna polymerase
40d1ud9a1



not modelled 96.1 11 Fold:DNA clamp
Superfamily:DNA clamp
Family:DNA polymerase processivity factor
41d1u7ba1



not modelled 95.1 13 Fold:DNA clamp
Superfamily:DNA clamp
Family:DNA polymerase processivity factor
42d1plqa1



not modelled 94.9 11 Fold:DNA clamp
Superfamily:DNA clamp
Family:DNA polymerase processivity factor
43c3pgeA_



not modelled 94.8 18 PDB header:dna binding protein
Chain: A: PDB Molecule:sumo-modified proliferating cell nuclear antigen;
PDBTitle: structure of sumoylated pcna
44c3l0xB_



not modelled 93.9 18 PDB header:replication
Chain: B: PDB Molecule:proliferating cell nuclear antigen;
PDBTitle: structure of split yeast pcna
45c3ggrB_



not modelled 91.3 12 PDB header:cell cycle
Chain: B: PDB Molecule:checkpoint protein hus1;
PDBTitle: crystal structure of the human rad9-hus1-rad1 complex
46c2obkE_



not modelled 80.6 15 PDB header:structural genomics, unknown function
Chain: E: PDB Molecule:selt/selw/selh selenoprotein domain;
PDBTitle: x-ray structure of the putative se binding protein from pseudomonas2 fluorescens. northeast structural genomics consortium target plr6.
47d2fa8a1



not modelled 76.2 15 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Selenoprotein W-related
48c2p0gB_



not modelled 70.7 10 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:selenoprotein w-related protein;
PDBTitle: crystal structure of selenoprotein w-related protein from2 vibrio cholerae. northeast structural genomics target vcr75
49d1czda1



not modelled 64.4 17 Fold:DNA clamp
Superfamily:DNA clamp
Family:DNA polymerase processivity factor
50c2ojlB_



not modelled 57.5 21 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:hypothetical protein;
PDBTitle: crystal structure of q7waf1_borpa from bordetella parapertussis.2 northeast structural genomics target bpr68.
51d1b77a1



not modelled 45.8 15 Fold:DNA clamp
Superfamily:DNA clamp
Family:DNA polymerase processivity factor
52c3l0wB_



not modelled 45.1 12 PDB header:replication
Chain: B: PDB Molecule:monoubiquitinated proliferating cell nuclear
PDBTitle: structure of split monoubiquitinated pcna with ubiquitin in2 position two
53c2npbA_



not modelled 21.4 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:selenoprotein w;
PDBTitle: nmr solution structure of mouse selw
54d1usha1



not modelled 21.2 8 Fold:5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
Superfamily:5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
Family:5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
55c3dexA_



not modelled 19.6 19 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:sav_2001;
PDBTitle: crystal structure of sav_2001 protein from streptomyces2 avermitilis, northeast structural genomics consortium3 target svr107.
56c1oidA_



not modelled 17.4 11 PDB header:hydrolase
Chain: A: PDB Molecule:protein usha;
PDBTitle: 5'-nucleotidase (e. coli) with an engineered disulfide2 bridge (s228c, p513c)
57c2zf9D_



not modelled 12.8 15 PDB header:structural protein
Chain: D: PDB Molecule:scae cell-surface anchored scaffoldin protein;
PDBTitle: crystal structure of a type iii cohesin module from the cellulosomal2 scae cell-surface anchoring scaffoldin of ruminococcus flavefaciens
58d1vqoe2



not modelled 11.8 24 Fold:Ribosomal protein L6
Superfamily:Ribosomal protein L6
Family:Ribosomal protein L6
59d2dkya1



not modelled 10.9 21 Fold:SAM domain-like
Superfamily:SAM/Pointed domain
Family:Variant SAM domain
60c3qyhG_



not modelled 8.6 29 PDB header:lyase
Chain: G: PDB Molecule:co-type nitrile hydratase alpha subunit;
PDBTitle: crystal structure of co-type nitrile hydratase beta-h71l from2 pseudomonas putida.
61c2pjzA_



not modelled 7.8 21 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein st1066;
PDBTitle: the crystal structure of putative cobalt transport atp-2 binding protein (cbio-2), st1066
62d1iwma_



not modelled 7.7 10 Fold:LolA-like prokaryotic lipoproteins and lipoprotein localization factors
Superfamily:Prokaryotic lipoproteins and lipoprotein localization factors
Family:Outer membrane lipoprotein receptor LolB
63c2dxbR_



not modelled 7.0 43 PDB header:hydrolase
Chain: R: PDB Molecule:thiocyanate hydrolase subunit gamma;
PDBTitle: recombinant thiocyanate hydrolase comprising partially-modified cobalt2 centers
64d1v29a_



not modelled 6.7 29 Fold:Nitrile hydratase alpha chain
Superfamily:Nitrile hydratase alpha chain
Family:Nitrile hydratase alpha chain
65d1b77a2



not modelled 6.7 8 Fold:DNA clamp
Superfamily:DNA clamp
Family:DNA polymerase processivity factor
66d1czda2



not modelled 6.2 11 Fold:DNA clamp
Superfamily:DNA clamp
Family:DNA polymerase processivity factor

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0