Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	I	V	I	A	P	D	S	Y	K	E	S	L	S	A	S	E	V	A	Q	A	I	E	K	G	F	R	E	I	F	P	D	A	Q	Y	V	S	V	P	V	A	D	G	G	E	G	T	V	E	A	M	I	A	A	T	Q	G	A	E
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	H	A	W	V	T	G	P	L	G	E	K	V	N	A	S	W	G	I	S	G	D	G	K	T	A	F	I	E	M	A	A	A	S	G	L	E	L	V	P	A	E	K	R	D	P	L	V	T	T	S	R	G	T	G	E	L	I	L	Q
Secondary structure
SS confidence
Disorder																																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	L	E	S	G	A	T	N	I	I	I	G	I	G	G	S	A	T	N	D	G	G	A	G	M	V	Q	A	L	G	A	K	L	C	D	A	N	G	N	E	I	G	F	G	G	G	S	L	N	T	L	N	D	I	D	I	S	G	L	D
Secondary structure
SS confidence
Disorder																																												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		P	R	L	K	D	C	V	I	R	V	A	C	D	V	T	N	P	L	V	G	D	N	G	A	S	R	I	F	G	P	Q	K	G	A	S	E	A	M	I	V	E	L	D	N	N	L	S	H	Y	A	E	V	I	K	K	A	L	H	V	D
Secondary structure
SS confidence
Disorder																												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		V	K	D	V	P	G	A	G	A	A	G	G	M	G	A	A	L	M	A	F	L	G	A	E	L	K	S	G	I	E	I	V	T	T	A	L	N	L	E	E	H	I	H	D	C	T	L	V	I	T	G	E	G	R	I	D	S	Q	S	I
Secondary structure
SS confidence
Disorder				?	?	?	?	?	?	?																																																?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		H	G	K	V	P	I	G	V	A	N	V	A	K	K	Y	H	K	P	V	I	G	I	A	G	S	L	T	D	D	V	G	V	V	H	Q	H	G	I	D	A	V	F	S	V	L	T	S	I	G	T	L	D	E	A	F	R	G	A	Y	D
Secondary structure
SS confidence
Disorder		?																																													?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.
Sequence		N	I	C	R	A	S	R	N	I	A	A	T	L	A	I	G	M	R	N	A	G
Secondary structure
SS confidence
Disorder																				?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3cwc chain B Region: 1 - 378 Aligned: 371 Modelled: 377 Confidence: 100.0% Identity: 67% PDB header:transferase Chain: B: PDB Molecule:putative glycerate kinase 2; PDBTitle: crystal structure of putative glycerate kinase 2 from salmonella2 typhimurium lt2 Phyre2 PDB 1to6 chain A Region: 1 - 376 Aligned: 369 Modelled: 376 Confidence: 100.0% Identity: 38% Fold: Glycerate kinase I Superfamily: Glycerate kinase I Family: Glycerate kinase I Phyre2 PDB 1e0t chain A domain 2 Region: 127 - 321 Aligned: 165 Modelled: 180 Confidence: 95.5% Identity: 14% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: Pyruvate kinase Phyre2 PDB 1liu chain A domain 2 Region: 127 - 321 Aligned: 170 Modelled: 180 Confidence: 93.8% Identity: 20% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: Pyruvate kinase Phyre2 PDB 1pkl chain A domain 2 Region: 127 - 321 Aligned: 168 Modelled: 195 Confidence: 93.4% Identity: 20% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: Pyruvate kinase Phyre2 PDB 1a3x chain A domain 2 Region: 127 - 321 Aligned: 168 Modelled: 180 Confidence: 90.7% Identity: 17% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: Pyruvate kinase Phyre2 PDB 1vb5 chain A Region: 281 - 329 Aligned: 49 Modelled: 49 Confidence: 88.8% Identity: 14% Fold: NagB/RpiA/CoA transferase-like Superfamily: NagB/RpiA/CoA transferase-like Family: IF2B-like Phyre2 PDB 1psw chain A Region: 274 - 365 Aligned: 79 Modelled: 79 Confidence: 88.8% Identity: 18% Fold: UDP-Glycosyltransferase/glycogen phosphorylase Superfamily: UDP-Glycosyltransferase/glycogen phosphorylase Family: ADP-heptose LPS heptosyltransferase II Phyre2 PDB 2g50 chain A domain 2 Region: 127 - 321 Aligned: 170 Modelled: 180 Confidence: 86.6% Identity: 18% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: Pyruvate kinase Phyre2 PDB 1w2w chain J Region: 278 - 325 Aligned: 48 Modelled: 48 Confidence: 84.1% Identity: 13% PDB header:isomerase Chain: J: PDB Molecule:5-methylthioribose-1-phosphate isomerase; PDBTitle: crystal structure of yeast ypr118w, a methylthioribose-1-2 phosphate isomerase related to regulatory eif2b subunits Phyre2 PDB 3ecs chain D Region: 281 - 325 Aligned: 45 Modelled: 43 Confidence: 83.8% Identity: 27% PDB header:translation Chain: D: PDB Molecule:translation initiation factor eif-2b subunit PDBTitle: crystal structure of human eif2b alpha Phyre2 PDB 1w5f chain A Region: 278 - 374 Aligned: 94 Modelled: 97 Confidence: 83.1% Identity: 17% PDB header:cell division Chain: A: PDB Molecule:cell division protein ftsz; PDBTitle: ftsz, t7 mutated, domain swapped (t. maritima) Phyre2 PDB 1ydg chain A Region: 1 - 43 Aligned: 39 Modelled: 43 Confidence: 83.0% Identity: 21% Fold: Flavodoxin-like Superfamily: Flavoproteins Family: WrbA-like Phyre2 PDB 3a11 chain D Region: 282 - 329 Aligned: 48 Modelled: 48 Confidence: 82.1% Identity: 17% PDB header:isomerase Chain: D: PDB Molecule:translation initiation factor eif-2b, delta PDBTitle: crystal structure of ribose-1,5-bisphosphate isomerase from2 thermococcus kodakaraensis kod1 Phyre2 PDB 1t5o chain A Region: 283 - 331 Aligned: 49 Modelled: 49 Confidence: 81.7% Identity: 29% Fold: NagB/RpiA/CoA transferase-like Superfamily: NagB/RpiA/CoA transferase-like Family: IF2B-like Phyre2 PDB 1xi3 chain A Region: 284 - 365 Aligned: 80 Modelled: 82 Confidence: 80.5% Identity: 14% Fold: TIM beta/alpha-barrel Superfamily: Thiamin phosphate synthase Family: Thiamin phosphate synthase Phyre2 PDB 1a3w chain B Region: 215 - 321 Aligned: 77 Modelled: 77 Confidence: 79.1% Identity: 19% PDB header:transferase Chain: B: PDB Molecule:pyruvate kinase; PDBTitle: pyruvate kinase from saccharomyces cerevisiae complexed with fbp, pg,2 mn2+ and k+ Phyre2 PDB 2h1f chain B Region: 274 - 329 Aligned: 43 Modelled: 43 Confidence: 77.2% Identity: 12% PDB header:transferase Chain: B: PDB Molecule:lipopolysaccharide heptosyltransferase-1; PDBTitle: e. coli heptosyltransferase waac with adp Phyre2 PDB 2yvk chain A Region: 283 - 325 Aligned: 43 Modelled: 43 Confidence: 75.0% Identity: 23% PDB header:isomerase Chain: A: PDB Molecule:methylthioribose-1-phosphate isomerase; PDBTitle: crystal structure of 5-methylthioribose 1-phosphate2 isomerase product complex from bacillus subtilis Phyre2 PDB 1aqf chain B Region: 262 - 321 Aligned: 60 Modelled: 60 Confidence: 74.4% Identity: 18% PDB header:transferase Chain: B: PDB Molecule:pyruvate kinase; PDBTitle: pyruvate kinase from rabbit muscle with mg, k, and l-2 phospholactate Phyre2 1 c3cwcB_ 2 d1to6a_ 3 d1e0ta2 4 d1liua2 5 d1pkla2 6 d1a3xa2 7 d1vb5a_ 8 d1pswa_ 9 d2g50a2 10 c1w2wJ_ 11 c3ecsD_ 12 c1w5fA_ 13 d1ydga_ 14 c3a11D_ 15 d1t5oa_ 16 d1xi3a_ 17 c1a3wB_ 18 c2h1fB_ 19 c2yvkA_ 20 c1aqfB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3cwcB_ 100.0 67 PDB header:transferase Chain: B: PDB Molecule:putative glycerate kinase 2; PDBTitle: crystal structure of putative glycerate kinase 2 from salmonella2 typhimurium lt2 2 d1to6a_ 100.0 38 Fold:Glycerate kinase I Superfamily:Glycerate kinase I Family:Glycerate kinase I 3 d1e0ta2 95.5 14 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 4 d1liua2 93.8 20 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 5 d1pkla2 93.4 20 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 6 d1a3xa2 90.7 17 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 7 d1vb5a_ 88.8 14 Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:IF2B-like 8 d1pswa_ 88.8 18 Fold:UDP-Glycosyltransferase/glycogen phosphorylase Superfamily:UDP-Glycosyltransferase/glycogen phosphorylase Family:ADP-heptose LPS heptosyltransferase II 9 d2g50a2 86.6 18 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 10 c1w2wJ_ 84.1 13 PDB header:isomerase Chain: J: PDB Molecule:5-methylthioribose-1-phosphate isomerase; PDBTitle: crystal structure of yeast ypr118w, a methylthioribose-1-2 phosphate isomerase related to regulatory eif2b subunits 11 c3ecsD_ 83.8 27 PDB header:translation Chain: D: PDB Molecule:translation initiation factor eif-2b subunit PDBTitle: crystal structure of human eif2b alpha 12 c1w5fA_ 83.1 17 PDB header:cell division Chain: A: PDB Molecule:cell division protein ftsz; PDBTitle: ftsz, t7 mutated, domain swapped (t. maritima) 13 d1ydga_ 83.0 21 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:WrbA-like 14 c3a11D_ 82.1 17 PDB header:isomerase Chain: D: PDB Molecule:translation initiation factor eif-2b, delta PDBTitle: crystal structure of ribose-1,5-bisphosphate isomerase from2 thermococcus kodakaraensis kod1 15 d1t5oa_ 81.7 29 Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:IF2B-like 16 d1xi3a_ 80.5 14 Fold:TIM beta/alpha-barrel Superfamily:Thiamin phosphate synthase Family:Thiamin phosphate synthase 17 c1a3wB_ 79.1 19 PDB header:transferase Chain: B: PDB Molecule:pyruvate kinase; PDBTitle: pyruvate kinase from saccharomyces cerevisiae complexed with fbp, pg,2 mn2+ and k+ 18 c2h1fB_ 77.2 12 PDB header:transferase Chain: B: PDB Molecule:lipopolysaccharide heptosyltransferase-1; PDBTitle: e. coli heptosyltransferase waac with adp 19 c2yvkA_ 75.0 23 PDB header:isomerase Chain: A: PDB Molecule:methylthioribose-1-phosphate isomerase; PDBTitle: crystal structure of 5-methylthioribose 1-phosphate2 isomerase product complex from bacillus subtilis 20 c1aqfB_ 74.4 18 PDB header:transferase Chain: B: PDB Molecule:pyruvate kinase; PDBTitle: pyruvate kinase from rabbit muscle with mg, k, and l-2 phospholactate 21 c3eoeC_ not modelled 74.3 20 PDB header:transferase Chain: C: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure of pyruvate kinase from toxoplasma gondii, 55.m00007 22 d1t9ka_ not modelled 74.0 21 Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:IF2B-like 23 c1t5aB_ not modelled 73.7 18 PDB header:transferase Chain: B: PDB Molecule:pyruvate kinase, m2 isozyme; PDBTitle: human pyruvate kinase m2 24 c3e0vB_ not modelled 73.2 18 PDB header:transferase Chain: B: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure of pyruvate kinase from leishmania mexicana in2 complex with sulphate ions 25 c2vgbB_ not modelled 73.0 18 PDB header:transferase Chain: B: PDB Molecule:pyruvate kinase isozymes r/l; PDBTitle: human erythrocyte pyruvate kinase 26 d2a0ua1 not modelled 72.6 22 Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:IF2B-like 27 c1w59B_ not modelled 72.5 18 PDB header:cell division Chain: B: PDB Molecule:cell division protein ftsz homolog 1; PDBTitle: ftsz dimer, empty (m. jannaschii) 28 d1rq2a1 not modelled 71.9 20 Fold:Tubulin nucleotide-binding domain-like Superfamily:Tubulin nucleotide-binding domain-like Family:Tubulin, GTPase domain 29 c2q1yB_ not modelled 70.9 20 PDB header:cell cycle, signaling protein Chain: B: PDB Molecule:cell division protein ftsz; PDBTitle: crystal structure of cell division protein ftsz from mycobacterium2 tuberculosis in complex with gtp-gamma-s 30 c3trjC_ not modelled 70.6 12 PDB header:isomerase Chain: C: PDB Molecule:phosphoheptose isomerase; PDBTitle: structure of a phosphoheptose isomerase from francisella tularensis 31 d2vapa1 not modelled 69.7 19 Fold:Tubulin nucleotide-binding domain-like Superfamily:Tubulin nucleotide-binding domain-like Family:Tubulin, GTPase domain 32 c3ma8A_ not modelled 69.1 15 PDB header:transferase Chain: A: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure of cgd1_2040, a pyruvate kinase from cryptosporidium2 parvum 33 c1pklB_ not modelled 68.8 18 PDB header:transferase Chain: B: PDB Molecule:protein (pyruvate kinase); PDBTitle: the structure of leishmania pyruvate kinase 34 c3t07D_ not modelled 67.4 23 PDB header:transferase/transferase inhibitor Chain: D: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure of s. aureus pyruvate kinase in complex with a2 naturally occurring bis-indole alkaloid 35 c2e28A_ not modelled 67.0 20 PDB header:transferase Chain: A: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure analysis of pyruvate kinase from bacillus2 stearothermophilus 36 c1e0tD_ not modelled 66.2 17 PDB header:phosphotransferase Chain: D: PDB Molecule:pyruvate kinase; PDBTitle: r292d mutant of e. coli pyruvate kinase 37 c2ppvA_ not modelled 65.7 16 PDB header:transferase Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a protein belonging to the upf0052 (se_0549) from2 staphylococcus epidermidis atcc 12228 at 2.00 a resolution 38 c3khdC_ not modelled 65.2 16 PDB header:transferase Chain: C: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure of pff1300w. 39 c2hjgA_ not modelled 65.2 14 PDB header:hydrolase Chain: A: PDB Molecule:gtp-binding protein enga; PDBTitle: the crystal structure of the b. subtilis yphc gtpase in2 complex with gdp 40 c3na3A_ not modelled 64.7 23 PDB header:protein binding Chain: A: PDB Molecule:dna mismatch repair protein mlh1; PDBTitle: mutl protein homolog 1 isoform 1 from homo sapiens 41 c2p0yA_ not modelled 64.0 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein lp_0780; PDBTitle: crystal structure of q88yi3_lacpl from lactobacillus2 plantarum. northeast structural genomics consortium target3 lpr6 42 c2rhoB_ not modelled 63.0 18 PDB header:cell cycle Chain: B: PDB Molecule:cell division protein ftsz; PDBTitle: synthetic gene encoded bacillus subtilis ftsz ncs dimer with2 bound gdp and gtp-gamma-s 43 c2f9iD_ not modelled 62.5 20 PDB header:transferase Chain: D: PDB Molecule:acetyl-coenzyme a carboxylase carboxyl PDBTitle: crystal structure of the carboxyltransferase subunit of acc2 from staphylococcus aureus 44 d2f9yb1 not modelled 61.7 17 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Biotin dependent carboxylase carboxyltransferase domain 45 c2f9yB_ not modelled 61.7 17 PDB header:ligase Chain: B: PDB Molecule:acetyl-coenzyme a carboxylase carboxyl transferase subunit PDBTitle: the crystal structure of the carboxyltransferase subunit of acc from2 escherichia coli 46 c2v82A_ not modelled 61.4 13 PDB header:lyase Chain: A: PDB Molecule:2-dehydro-3-deoxy-6-phosphogalactonate aldolase; PDBTitle: kdpgal complexed to kdpgal 47 c3o63B_ not modelled 60.2 23 PDB header:transferase Chain: B: PDB Molecule:probable thiamine-phosphate pyrophosphorylase; PDBTitle: crystal structure of thiamin phosphate synthase from mycobacterium2 tuberculosis 48 d1ofua1 not modelled 59.1 20 Fold:Tubulin nucleotide-binding domain-like Superfamily:Tubulin nucleotide-binding domain-like Family:Tubulin, GTPase domain 49 d2hzba1 not modelled 56.9 16 Fold:CofD-like Superfamily:CofD-like Family:CofD-like 50 c2vxyA_ not modelled 56.1 19 PDB header:cell cycle Chain: A: PDB Molecule:cell division protein ftsz; PDBTitle: the structure of ftsz from bacillus subtilis at 1.7a2 resolution 51 c3hbmA_ not modelled 55.2 21 PDB header:hydrolase Chain: A: PDB Molecule:udp-sugar hydrolase; PDBTitle: crystal structure of pseg from campylobacter jejuni 52 d1tk9a_ not modelled 55.1 13 Fold:SIS domain Superfamily:SIS domain Family:mono-SIS domain 53 c2ze3A_ not modelled 54.8 8 PDB header:isomerase Chain: A: PDB Molecule:dfa0005; PDBTitle: crystal structure of dfa0005 complexed with alpha-ketoglutarate: a2 novel member of the icl/pepm superfamily from alkali-tolerant3 deinococcus ficus 54 d1diha1 not modelled 54.3 16 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 55 d1j0aa_ not modelled 53.8 26 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 56 d1f8ya_ not modelled 53.7 10 Fold:Flavodoxin-like Superfamily:N-(deoxy)ribosyltransferase-like Family:N-deoxyribosyltransferase 57 d1izca_ not modelled 53.6 17 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:HpcH/HpaI aldolase 58 c1izcA_ not modelled 53.6 17 PDB header:lyase Chain: A: PDB Molecule:macrophomate synthase intermolecular diels-alderase; PDBTitle: crystal structure analysis of macrophomate synthase 59 c1drwA_ not modelled 53.2 18 PDB header:oxidoreductase Chain: A: PDB Molecule:dihydrodipicolinate reductase; PDBTitle: escherichia coli dhpr/nhdh complex 60 c3qz6A_ not modelled 52.6 10 PDB header:lyase Chain: A: PDB Molecule:hpch/hpai aldolase; PDBTitle: the crystal structure of hpch/hpai aldolase from desulfitobacterium2 hafniense dcb-2 61 c1ofuB_ not modelled 52.3 21 PDB header:bacterial cell division inhibitor Chain: B: PDB Molecule:cell division protein ftsz; PDBTitle: crystal structure of sula:ftsz from pseudomonas aeruginosa 62 c1pixB_ not modelled 52.3 14 PDB header:lyase Chain: B: PDB Molecule:glutaconyl-coa decarboxylase a subunit; PDBTitle: crystal structure of the carboxyltransferase subunit of the2 bacterial ion pump glutaconyl-coenzyme a decarboxylase 63 d1pjqa1 not modelled 52.1 21 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Siroheme synthase N-terminal domain-like 64 d1pixa2 not modelled 51.4 20 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Biotin dependent carboxylase carboxyltransferase domain 65 d1vrga1 not modelled 48.7 35 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Biotin dependent carboxylase carboxyltransferase domain 66 d1vm6a3 not modelled 48.6 25 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 67 d1j6ua1 not modelled 48.2 15 Fold:MurCD N-terminal domain Superfamily:MurCD N-terminal domain Family:MurCD N-terminal domain 68 c2vawA_ not modelled 47.2 19 PDB header:cell cycle Chain: A: PDB Molecule:cell division protein ftsz; PDBTitle: ftsz pseudomonas aeruginosa gdp 69 c1yadD_ not modelled 46.7 20 PDB header:transcription Chain: D: PDB Molecule:regulatory protein teni; PDBTitle: structure of teni from bacillus subtilis 70 d1q7ra_ not modelled 46.5 18 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT) 71 d1wv2a_ not modelled 46.0 19 Fold:TIM beta/alpha-barrel Superfamily:ThiG-like Family:ThiG-like 72 c3ct7E_ not modelled 45.8 11 PDB header:isomerase Chain: E: PDB Molecule:d-allulose-6-phosphate 3-epimerase; PDBTitle: crystal structure of d-allulose 6-phosphate 3-epimerase2 from escherichia coli k-12 73 c2bf9A_ not modelled 45.1 22 PDB header:hormone Chain: A: PDB Molecule:pancreatic hormone; PDBTitle: anisotropic refinement of avian (turkey) pancreatic2 polypeptide at 0.99 angstroms resolution. 74 d1ycga1 not modelled 44.5 29 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 75 d1on3a1 not modelled 44.4 16 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Biotin dependent carboxylase carboxyltransferase domain 76 c1bknA_ not modelled 44.3 38 PDB header:dna repair Chain: A: PDB Molecule:mutl; PDBTitle: crystal structure of an n-terminal 40kd fragment of e. coli2 dna mismatch repair protein mutl 77 d1x92a_ not modelled 44.0 12 Fold:SIS domain Superfamily:SIS domain Family:mono-SIS domain 78 c1d4fD_ not modelled 44.0 21 PDB header:hydrolase Chain: D: PDB Molecule:s-adenosylhomocysteine hydrolase; PDBTitle: crystal structure of recombinant rat-liver d244e mutant s-2 adenosylhomocysteine hydrolase 79 c2yvaB_ not modelled 43.7 9 PDB header:dna binding protein Chain: B: PDB Molecule:dnaa initiator-associating protein diaa; PDBTitle: crystal structure of escherichia coli diaa 80 c1ronA_ not modelled 42.7 22 PDB header:neuropeptide Chain: A: PDB Molecule:neuropeptide y; PDBTitle: nmr solution structure of human neuropeptide y 81 c2x3yA_ not modelled 42.3 12 PDB header:isomerase Chain: A: PDB Molecule:phosphoheptose isomerase; PDBTitle: crystal structure of gmha from burkholderia pseudomallei 82 c1tz5A_ not modelled 42.1 15 PDB header:hormone/growth factor Chain: A: PDB Molecule:chimera of pancreatic hormone and neuropeptide y; PDBTitle: [pnpy19-23]-hpp bound to dpc micelles 83 c3hgmD_ not modelled 42.1 22 PDB header:signaling protein Chain: D: PDB Molecule:universal stress protein tead; PDBTitle: universal stress protein tead from the trap transporter2 teaabc of halomonas elongata 84 d1nmpa_ not modelled 42.0 17 Fold:NIF3 (NGG1p interacting factor 3)-like Superfamily:NIF3 (NGG1p interacting factor 3)-like Family:NIF3 (NGG1p interacting factor 3)-like 85 c1x0uB_ not modelled 42.0 25 PDB header:lyase Chain: B: PDB Molecule:hypothetical methylmalonyl-coa decarboxylase alpha subunit; PDBTitle: crystal structure of the carboxyl transferase subunit of putative pcc2 of sulfolobus tokodaii 86 c1xnwD_ not modelled 41.5 29 PDB header:ligase Chain: D: PDB Molecule:propionyl-coa carboxylase complex b subunit; PDBTitle: acyl-coa carboxylase beta subunit from s. coelicolor (pccb),2 apo form #2, mutant d422i 87 c3glmD_ not modelled 41.5 23 PDB header:lyase Chain: D: PDB Molecule:glutaconyl-coa decarboxylase subunit a; PDBTitle: glutaconyl-coa decarboxylase a subunit from clostridium2 symbiosum co-crystallized with crotonyl-coa 88 d1w5fa1 not modelled 41.4 18 Fold:Tubulin nucleotide-binding domain-like Superfamily:Tubulin nucleotide-binding domain-like Family:Tubulin, GTPase domain 89 c2yybA_ not modelled 41.2 32 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein ttha1606; PDBTitle: crystal structure of ttha1606 from thermus thermophilus hb8 90 c3h4lB_ not modelled 41.1 25 PDB header:dna binding protein, protein binding Chain: B: PDB Molecule:dna mismatch repair protein pms1; PDBTitle: crystal structure of n terminal domain of a dna repair protein 91 d1vima_ not modelled 40.8 13 Fold:SIS domain Superfamily:SIS domain Family:mono-SIS domain 92 d1s2da_ not modelled 40.5 21 Fold:Flavodoxin-like Superfamily:N-(deoxy)ribosyltransferase-like Family:N-deoxyribosyltransferase 93 d1w41a1 not modelled 40.4 13 Fold:Bacillus chorismate mutase-like Superfamily:L30e-like Family:L30e/L7ae ribosomal proteins 94 c3ijpA_ not modelled 40.2 18 PDB header:oxidoreductase Chain: A: PDB Molecule:dihydrodipicolinate reductase; PDBTitle: crystal structure of dihydrodipicolinate reductase from2 bartonella henselae at 2.0a resolution 95 c3tovB_ not modelled 40.1 22 PDB header:transferase Chain: B: PDB Molecule:glycosyl transferase family 9; PDBTitle: the crystal structure of the glycosyl transferase family 9 from2 veillonella parvula dsm 2008 96 c1on3E_ not modelled 40.1 19 PDB header:transferase Chain: E: PDB Molecule:methylmalonyl-coa carboxyltransferase 12s PDBTitle: transcarboxylase 12s crystal structure: hexamer assembly2 and substrate binding to a multienzyme core (with3 methylmalonyl-coenzyme a and methylmalonic acid bound) 97 c3kv1A_ not modelled 39.7 19 PDB header:transcription Chain: A: PDB Molecule:transcriptional repressor; PDBTitle: crystal structure of putative sugar-binding domain of transcriptional2 repressor from vibrio fischeri 98 d1e0ta3 not modelled 39.7 13 Fold:Pyruvate kinase C-terminal domain-like Superfamily:PK C-terminal domain-like Family:Pyruvate kinase, C-terminal domain 99 c3n6rF_ not modelled 39.6 29 PDB header:ligase Chain: F: PDB Molecule:propionyl-coa carboxylase, beta subunit; PDBTitle: crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc) 100 c2dezA_ not modelled 39.3 22 PDB header:neuropeptide Chain: A: PDB Molecule:peptide yy; PDBTitle: structure of human pyy 101 c2q7xA_ not modelled 39.2 10 PDB header:transferase Chain: A: PDB Molecule:upf0052 protein sp_1565; PDBTitle: crystal structure of a putative phospho transferase (sp_1565) from2 streptococcus pneumoniae tigr4 at 2.00 a resolution 102 d1p3da1 not modelled 38.3 16 Fold:MurCD N-terminal domain Superfamily:MurCD N-terminal domain Family:MurCD N-terminal domain 103 c1vrgE_ not modelled 38.2 33 PDB header:ligase Chain: E: PDB Molecule:propionyl-coa carboxylase, beta subunit; PDBTitle: crystal structure of propionyl-coa carboxylase, beta subunit (tm0716)2 from thermotoga maritima at 2.30 a resolution 104 d2a7sa1 not modelled 38.0 31 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Biotin dependent carboxylase carboxyltransferase domain 105 c3iz6A_ not modelled 37.3 23 PDB header:ribosome Chain: A: PDB Molecule:40s ribosomal protein sa (s2p); PDBTitle: localization of the small subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome 106 c2zwmA_ not modelled 37.0 20 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulatory protein yycf; PDBTitle: crystal structure of yycf receiver domain from bacillus2 subtilis 107 d1dxea_ not modelled 36.9 20 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:HpcH/HpaI aldolase 108 c3bzrA_ not modelled 36.7 22 PDB header:membrane protein, protein transport Chain: A: PDB Molecule:escu; PDBTitle: crystal structure of escu c-terminal domain with n262d mutation, space2 group p 41 21 2 109 d3bzra1 not modelled 36.7 22 Fold:EscU C-terminal domain-like Superfamily:EscU C-terminal domain-like Family:EscU C-terminal domain-like 110 c3pqeD_ not modelled 36.5 19 PDB header:oxidoreductase Chain: D: PDB Molecule:l-lactate dehydrogenase; PDBTitle: crystal structure of l-lactate dehydrogenase from bacillus subtilis2 with h171c mutation 111 d1xnya1 not modelled 36.4 29 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Biotin dependent carboxylase carboxyltransferase domain 112 c1ea6A_ not modelled 36.3 34 PDB header:dna repair Chain: A: PDB Molecule:pms1 protein homolog 2; PDBTitle: n-terminal 40kda fragment of nhpms2 complexed with adp 113 c2decA_ not modelled 35.9 10 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:325aa long hypothetical protein; PDBTitle: crystal structure of the ph0510 protein from pyrococcus horikoshii ot3 114 c2yxbA_ not modelled 35.9 12 PDB header:isomerase Chain: A: PDB Molecule:coenzyme b12-dependent mutase; PDBTitle: crystal structure of the methylmalonyl-coa mutase alpha-subunit from2 aeropyrum pernix 115 d2ffea1 not modelled 35.2 17 Fold:CofD-like Superfamily:CofD-like Family:CofD-like 116 c1zosE_ not modelled 35.0 22 PDB header:hydrolase Chain: E: PDB Molecule:5'-methylthioadenosine / s-adenosylhomocysteine PDBTitle: structure of 5'-methylthionadenosine/s-adenosylhomocysteine2 nucleosidase from s. pneumoniae with a transition-state3 inhibitor mt-imma 117 d1efvb_ not modelled 34.8 20 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ETFP subunits 118 d1t0kb_ not modelled 34.8 15 Fold:Bacillus chorismate mutase-like Superfamily:L30e-like Family:L30e/L7ae ribosomal proteins 119 c2xhzC_ not modelled 34.7 23 PDB header:isomerase Chain: C: PDB Molecule:arabinose 5-phosphate isomerase; PDBTitle: probing the active site of the sugar isomerase domain from e. coli2 arabinose-5-phosphate isomerase via x-ray crystallography 120 c3oirA_ not modelled 34.7 12 PDB header:transport protein Chain: A: PDB Molecule:sulfate transporter sulfate transporter family protein; PDBTitle: crystal structure of sulfate transporter family protein from wolinella2 succinogenes

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0