PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c1zosE_

Fold library id	PDB Header	Molecule	Title
c1zosE_	PDB header: hydrolase	Chain: E: PDB Molecule: 5'-methylthioadenosine / s-adenosylhomocysteine	PDBTitle: structure of 5'-methylthionadenosine/s-adenosylhomocysteine2 nucleosidase from s. pneumoniae with a transition-state3 inhibitor mt-imma

Links to external resources
Added to library: Tue Mar 16 13:21:31 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence M K I G I I A A M P E E L A Y L V Q H L D N T Q E Q V V L G N T Y H T G T I A S H E V V L V E S G I G K V M S A M S V A I L A D H F Q V D A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S G G G T T
T T T T
S S T S
S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence L I N T G S A G A V A E G I A V G D V V I A D K L A Y H D V D V T A F G Y A Y G Q M A Q Q P L Y F E S D K T F V A Q I Q E S L S Q L D Q N W

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S T T
T T
S S
G G G T
T T
T T S
S
S
T T
T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence H L G L I A T G D S F V A G N D K I E A I K S H F P E V L A V E M E G A A I A Q A A H T L N L P V L V I R A M S D N A N H E A N I F F D E F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
S
T T S S T T
S S T T

. . . . . . . . . 220 . . . . . . . . . 230

Sequence I I E A G R R S A Q V L L A F L K A L D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	M	K	I	G	I	I	A	A	M	P	E	E	L	A	Y	L	V	Q	H	L	D	N	T	Q	E	Q	V	V	L	G	N	T	Y	H	T	G	T	I	A	S	H	E	V	V	L	V	E	S	G	I	G	K	V	M	S	A	M	S	V	A	I	L	A	D	H	F	Q	V	D	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								S	S	G	G	G	T						T										T	T									T	T										S	S														T	S			S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	L	I	N	T	G	S	A	G	A	V	A	E	G	I	A	V	G	D	V	V	I	A	D	K	L	A	Y	H	D	V	D	V	T	A	F	G	Y	A	Y	G	Q	M	A	Q	Q	P	L	Y	F	E	S	D	K	T	F	V	A	Q	I	Q	E	S	L	S	Q	L	D	Q	N	W
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											S	T	T			T	T											S	S				G	G	G	T			T	T			T	T	S		S																S		T	T		T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	H	L	G	L	I	A	T	G	D	S	F	V	A	G	N	D	K	I	E	A	I	K	S	H	F	P	E	V	L	A	V	E	M	E	G	A	A	I	A	Q	A	A	H	T	L	N	L	P	V	L	V	I	R	A	M	S	D	N	A	N	H	E	A	N	I	F	F	D	E	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									S	S				S												T	T						S	S											T	T													S	S	T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230
Sequence	I	I	E	A	G	R	R	S	A	Q	V	L	L	A	F	L	K	A	L	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)