Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	D	L	I	Q	R	P	R	R	L	R	K	S	P	A	L	R	A	M	F	E	E	T	T	L	S	L	N	D	L	V	L	P	I	F	V	E	E	E	I	D	D	Y	K	A	V	E	A	M	P	G	V	M	R	I	P	E	K	H
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?														?	?																?	?	?	?			?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	A	R	E	I	E	R	I	A	N	A	G	I	R	S	V	M	T	F	G	I	S	H	H	T	D	E	T	G	S	D	A	W	R	E	D	G	L	V	A	R	M	S	R	I	C	K	Q	T	V	P	E	M	I	V	M	S	D	T	C
Secondary structure
SS confidence
Disorder																								?	?					?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		F	C	E	Y	T	S	H	G	H	C	G	V	L	C	E	H	G	V	D	N	D	A	T	L	E	N	L	G	K	Q	A	V	V	A	A	A	A	G	A	D	F	I	A	P	S	A	A	M	D	G	Q	V	Q	A	I	R	Q	A	L	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	A	G	F	K	D	T	A	I	M	S	Y	S	T	K	F	A	S	S	F	Y	G	P	F	R	E	A	A	G	S	A	L	K	G	D	R	K	S	Y	Q	M	N	P	M	N	R	R	E	A	I	R	E	S	L	L	D	E	A	Q	G
Secondary structure
SS confidence
Disorder																														?	?	?	?	?		?	?		?		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	D	C	L	M	V	K	P	A	G	A	Y	L	D	I	V	R	E	L	R	E	R	T	E	L	P	I	G	A	Y	Q	V	S	G	E	Y	A	M	I	K	F	A	A	L	A	G	A	I	D	E	E	K	V	V	L	E	S	L	G	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.
Sequence		I	K	R	A	G	A	D	L	I	F	S	Y	F	A	L	D	L	A	E	K	K	I	L	R
Secondary structure
SS confidence
Disorder																						?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1l6s chain A Region: 2 - 324 Aligned: 322 Modelled: 323 Confidence: 100.0% Identity: 100% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) Phyre2 PDB 2c1h chain A domain 1 Region: 5 - 320 Aligned: 316 Modelled: 316 Confidence: 100.0% Identity: 47% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) Phyre2 PDB 3obk chain H Region: 1 - 319 Aligned: 318 Modelled: 319 Confidence: 100.0% Identity: 43% PDB header:lyase Chain: H: PDB Molecule:delta-aminolevulinic acid dehydratase; PDBTitle: crystal structure of delta-aminolevulinic acid dehydratase2 (porphobilinogen synthase) from toxoplasma gondii me49 in complex3 with the reaction product porphobilinogen Phyre2 PDB 1gzg chain A Region: 4 - 320 Aligned: 316 Modelled: 317 Confidence: 100.0% Identity: 41% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) Phyre2 PDB 1h7n chain A Region: 13 - 319 Aligned: 307 Modelled: 307 Confidence: 100.0% Identity: 40% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) Phyre2 PDB 1pv8 chain A Region: 13 - 319 Aligned: 267 Modelled: 293 Confidence: 100.0% Identity: 41% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) Phyre2 PDB 1ps9 chain A domain 1 Region: 58 - 261 Aligned: 164 Modelled: 188 Confidence: 97.4% Identity: 19% Fold: TIM beta/alpha-barrel Superfamily: FMN-linked oxidoreductases Family: FMN-linked oxidoreductases Phyre2 PDB 1wbh chain A domain 1 Region: 32 - 269 Aligned: 140 Modelled: 144 Confidence: 97.2% Identity: 24% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 1svd chain A domain 1 Region: 143 - 311 Aligned: 141 Modelled: 148 Confidence: 96.9% Identity: 18% Fold: TIM beta/alpha-barrel Superfamily: RuBisCo, C-terminal domain Family: RuBisCo, large subunit, C-terminal domain Phyre2 PDB 2h90 chain A Region: 58 - 276 Aligned: 181 Modelled: 204 Confidence: 96.9% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:xenobiotic reductase a; PDBTitle: xenobiotic reductase a in complex with coumarin Phyre2 PDB 3tha chain B Region: 57 - 311 Aligned: 185 Modelled: 190 Confidence: 96.7% Identity: 17% PDB header:lyase Chain: B: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: tryptophan synthase subunit alpha from campylobacter jejuni. Phyre2 PDB 2qyg chain C Region: 143 - 269 Aligned: 106 Modelled: 111 Confidence: 96.6% Identity: 21% PDB header:unknown function Chain: C: PDB Molecule:ribulose bisphosphate carboxylase-like protein 2; PDBTitle: crystal structure of a rubisco-like protein rlp2 from rhodopseudomonas2 palustris Phyre2 PDB 1ykw chain A domain 1 Region: 143 - 269 Aligned: 106 Modelled: 111 Confidence: 96.6% Identity: 21% Fold: TIM beta/alpha-barrel Superfamily: RuBisCo, C-terminal domain Family: RuBisCo, large subunit, C-terminal domain Phyre2 PDB 1ps9 chain A Region: 58 - 289 Aligned: 152 Modelled: 152 Confidence: 96.6% Identity: 24% PDB header:oxidoreductase Chain: A: PDB Molecule:2,4-dienoyl-coa reductase; PDBTitle: the crystal structure and reaction mechanism of e. coli 2,4-2 dienoyl coa reductase Phyre2 PDB 3eoo chain L Region: 99 - 274 Aligned: 131 Modelled: 136 Confidence: 96.5% Identity: 21% PDB header:lyase Chain: L: PDB Molecule:methylisocitrate lyase; PDBTitle: 2.9a crystal structure of methyl-isocitrate lyase from2 burkholderia pseudomallei Phyre2 PDB 3nwr chain A Region: 143 - 269 Aligned: 105 Modelled: 105 Confidence: 96.4% Identity: 21% PDB header:lyase Chain: A: PDB Molecule:a rubisco-like protein; PDBTitle: crystal structure of a rubisco-like protein from burkholderia fungorum Phyre2 PDB 1tel chain A Region: 143 - 269 Aligned: 108 Modelled: 111 Confidence: 96.4% Identity: 20% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:ribulose bisphosphate carboxylase, large subunit; PDBTitle: crystal structure of a rubisco-like protein from chlorobium2 tepidum Phyre2 PDB 3qfw chain B Region: 143 - 269 Aligned: 106 Modelled: 106 Confidence: 96.4% Identity: 23% PDB header:lyase Chain: B: PDB Molecule:ribulose-1,5-bisphosphate carboxylase/oxygenase large PDBTitle: crystal structure of rubisco-like protein from rhodopseudomonas2 palustris Phyre2 PDB 1rld chain B Region: 143 - 269 Aligned: 108 Modelled: 111 Confidence: 96.3% Identity: 17% PDB header:lyase(carbon-carbon) Chain: B: PDB Molecule:ribulose 1,5 bisphosphate carboxylase/oxygenase (large PDBTitle: solid-state phase transition in the crystal structure of ribulose 1,5-2 biphosphate carboxylase(slash)oxygenase Phyre2 PDB 1rcx chain H Region: 143 - 269 Aligned: 106 Modelled: 106 Confidence: 96.2% Identity: 17% PDB header:lyase (carbon-carbon) Chain: H: PDB Molecule:ribulose bisphosphate carboxylase/oxygenase; PDBTitle: non-activated spinach rubisco in complex with its substrate2 ribulose-1,5-bisphosphate Phyre2 1 d1l6sa_ 2 d2c1ha1 3 c3obkH_ 4 d1gzga_ 5 d1h7na_ 6 d1pv8a_ 7 d1ps9a1 8 d1wbha1 9 d1svda1 10 c2h90A_ 11 c3thaB_ 12 c2qygC_ 13 d1ykwa1 14 c1ps9A_ 15 c3eooL_ 16 c3nwrA_ 17 c1telA_ 18 c3qfwB_ 19 c1rldB_ 20 c1rcxH_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1l6sa_ 100.0 100 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 2 d2c1ha1 100.0 47 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 3 c3obkH_ 100.0 43 PDB header:lyase Chain: H: PDB Molecule:delta-aminolevulinic acid dehydratase; PDBTitle: crystal structure of delta-aminolevulinic acid dehydratase2 (porphobilinogen synthase) from toxoplasma gondii me49 in complex3 with the reaction product porphobilinogen 4 d1gzga_ 100.0 41 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 5 d1h7na_ 100.0 40 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 6 d1pv8a_ 100.0 41 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 7 d1ps9a1 97.4 19 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 8 d1wbha1 97.2 24 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 9 d1svda1 96.9 18 Fold:TIM beta/alpha-barrel Superfamily:RuBisCo, C-terminal domain Family:RuBisCo, large subunit, C-terminal domain 10 c2h90A_ 96.9 17 PDB header:oxidoreductase Chain: A: PDB Molecule:xenobiotic reductase a; PDBTitle: xenobiotic reductase a in complex with coumarin 11 c3thaB_ 96.7 17 PDB header:lyase Chain: B: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: tryptophan synthase subunit alpha from campylobacter jejuni. 12 c2qygC_ 96.6 21 PDB header:unknown function Chain: C: PDB Molecule:ribulose bisphosphate carboxylase-like protein 2; PDBTitle: crystal structure of a rubisco-like protein rlp2 from rhodopseudomonas2 palustris 13 d1ykwa1 96.6 21 Fold:TIM beta/alpha-barrel Superfamily:RuBisCo, C-terminal domain Family:RuBisCo, large subunit, C-terminal domain 14 c1ps9A_ 96.6 24 PDB header:oxidoreductase Chain: A: PDB Molecule:2,4-dienoyl-coa reductase; PDBTitle: the crystal structure and reaction mechanism of e. coli 2,4-2 dienoyl coa reductase 15 c3eooL_ 96.5 21 PDB header:lyase Chain: L: PDB Molecule:methylisocitrate lyase; PDBTitle: 2.9a crystal structure of methyl-isocitrate lyase from2 burkholderia pseudomallei 16 c3nwrA_ 96.4 21 PDB header:lyase Chain: A: PDB Molecule:a rubisco-like protein; PDBTitle: crystal structure of a rubisco-like protein from burkholderia fungorum 17 c1telA_ 96.4 20 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:ribulose bisphosphate carboxylase, large subunit; PDBTitle: crystal structure of a rubisco-like protein from chlorobium2 tepidum 18 c3qfwB_ 96.4 23 PDB header:lyase Chain: B: PDB Molecule:ribulose-1,5-bisphosphate carboxylase/oxygenase large PDBTitle: crystal structure of rubisco-like protein from rhodopseudomonas2 palustris 19 c1rldB_ 96.3 17 PDB header:lyase(carbon-carbon) Chain: B: PDB Molecule:ribulose 1,5 bisphosphate carboxylase/oxygenase (large PDBTitle: solid-state phase transition in the crystal structure of ribulose 1,5-2 biphosphate carboxylase(slash)oxygenase 20 c1rcxH_ 96.2 17 PDB header:lyase (carbon-carbon) Chain: H: PDB Molecule:ribulose bisphosphate carboxylase/oxygenase; PDBTitle: non-activated spinach rubisco in complex with its substrate2 ribulose-1,5-bisphosphate 21 d1ej7l1 not modelled 96.2 19 Fold:TIM beta/alpha-barrel Superfamily:RuBisCo, C-terminal domain Family:RuBisCo, large subunit, C-terminal domain 22 d1mxsa_ not modelled 96.2 21 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 23 d5ruba1 not modelled 96.0 18 Fold:TIM beta/alpha-barrel Superfamily:RuBisCo, C-terminal domain Family:RuBisCo, large subunit, C-terminal domain 24 c3fk4A_ not modelled 96.0 25 PDB header:isomerase Chain: A: PDB Molecule:rubisco-like protein; PDBTitle: crystal structure of rubisco-like protein from bacillus2 cereus atcc 14579 25 d1geha1 not modelled 96.0 17 Fold:TIM beta/alpha-barrel Superfamily:RuBisCo, C-terminal domain Family:RuBisCo, large subunit, C-terminal domain 26 d1bxna1 not modelled 95.9 18 Fold:TIM beta/alpha-barrel Superfamily:RuBisCo, C-terminal domain Family:RuBisCo, large subunit, C-terminal domain 27 d2d69a1 not modelled 95.9 19 Fold:TIM beta/alpha-barrel Superfamily:RuBisCo, C-terminal domain Family:RuBisCo, large subunit, C-terminal domain 28 c2zviB_ not modelled 95.8 25 PDB header:isomerase Chain: B: PDB Molecule:2,3-diketo-5-methylthiopentyl-1-phosphate PDBTitle: crystal structure of 2,3-diketo-5-methylthiopentyl-1-2 phosphate enolase from bacillus subtilis 29 c2eq5D_ not modelled 95.8 21 PDB header:isomerase Chain: D: PDB Molecule:228aa long hypothetical hydantoin racemase; PDBTitle: crystal structure of hydantoin racemase from pyrococcus horikoshii ot3 30 d1rbla1 not modelled 95.8 15 Fold:TIM beta/alpha-barrel Superfamily:RuBisCo, C-terminal domain Family:RuBisCo, large subunit, C-terminal domain 31 c1gehE_ not modelled 95.7 17 PDB header:lyase Chain: E: PDB Molecule:ribulose-1,5-bisphosphate carboxylase/oxygenase; PDBTitle: crystal structure of archaeal rubisco (ribulose 1,5-bisphosphate2 carboxylase/oxygenase) 32 c2ze3A_ not modelled 95.7 22 PDB header:isomerase Chain: A: PDB Molecule:dfa0005; PDBTitle: crystal structure of dfa0005 complexed with alpha-ketoglutarate: a2 novel member of the icl/pepm superfamily from alkali-tolerant3 deinococcus ficus 33 c2d69B_ not modelled 95.7 19 PDB header:lyase Chain: B: PDB Molecule:ribulose bisphosphate carboxylase; PDBTitle: crystal structure of the complex of sulfate ion and octameric2 ribulose-1,5-bisphosphate carboxylase/oxygenase (rubisco) from3 pyrococcus horikoshii ot3 (form-2 crystal) 34 c3labA_ not modelled 95.6 23 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative kdpg (2-keto-3-deoxy-6-phosphogluconate) PDBTitle: crystal structure of a putative kdpg (2-keto-3-deoxy-6-2 phosphogluconate) aldolase from oleispira antarctica 35 c2oemA_ not modelled 95.6 26 PDB header:isomerase Chain: A: PDB Molecule:2,3-diketo-5-methylthiopentyl-1-phosphate enolase; PDBTitle: crystal structure of a rubisco-like protein from geobacillus2 kaustophilus liganded with mg2+ and 2,3-diketohexane 1-phosphate 36 d1muma_ not modelled 95.6 26 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 37 d1wdda1 not modelled 95.4 17 Fold:TIM beta/alpha-barrel Superfamily:RuBisCo, C-terminal domain Family:RuBisCo, large subunit, C-terminal domain 38 d1oy0a_ not modelled 95.3 21 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Ketopantoate hydroxymethyltransferase PanB 39 c3fa4D_ not modelled 95.2 15 PDB header:lyase Chain: D: PDB Molecule:2,3-dimethylmalate lyase; PDBTitle: crystal structure of 2,3-dimethylmalate lyase, a pep mutase/isocitrate2 lyase superfamily member, triclinic crystal form 40 c3gr7A_ not modelled 95.1 18 PDB header:oxidoreductase Chain: A: PDB Molecule:nadph dehydrogenase; PDBTitle: structure of oye from geobacillus kaustophilus, hexagonal2 crystal form 41 d8ruca1 not modelled 95.0 17 Fold:TIM beta/alpha-barrel Superfamily:RuBisCo, C-terminal domain Family:RuBisCo, large subunit, C-terminal domain 42 d1djqa1 not modelled 94.8 15 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 43 c3ez4B_ not modelled 94.7 19 PDB header:transferase Chain: B: PDB Molecule:3-methyl-2-oxobutanoate hydroxymethyltransferase; PDBTitle: crystal structure of 3-methyl-2-oxobutanoate2 hydroxymethyltransferase from burkholderia pseudomallei 44 c3hf3A_ not modelled 94.6 18 PDB header:oxidoreductase Chain: A: PDB Molecule:chromate reductase; PDBTitle: old yellow enzyme from thermus scotoductus sa-01 45 c1zlpA_ not modelled 94.5 25 PDB header:lyase Chain: A: PDB Molecule:petal death protein; PDBTitle: petal death protein psr132 with cysteine-linked glutaraldehyde forming2 a thiohemiacetal adduct 46 d1gk8a1 not modelled 94.5 16 Fold:TIM beta/alpha-barrel Superfamily:RuBisCo, C-terminal domain Family:RuBisCo, large subunit, C-terminal domain 47 c2rusB_ not modelled 94.4 17 PDB header:lyase(carbon-carbon) Chain: B: PDB Molecule:rubisco (ribulose-1,5-bisphosphate PDBTitle: crystal structure of the ternary complex of ribulose-1,5-2 bisphosphate carboxylase, mg(ii), and activator co2 at 2.3-3 angstroms resolution 48 d1vjia_ not modelled 94.4 16 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 49 d1vhca_ not modelled 94.2 21 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 50 d1bwva1 not modelled 94.1 21 Fold:TIM beta/alpha-barrel Superfamily:RuBisCo, C-terminal domain Family:RuBisCo, large subunit, C-terminal domain 51 d1rd5a_ not modelled 94.0 16 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 52 c1djnB_ not modelled 93.9 17 PDB header:oxidoreductase Chain: B: PDB Molecule:trimethylamine dehydrogenase; PDBTitle: structural and biochemical characterization of recombinant wild type2 trimethylamine dehydrogenase from methylophilus methylotrophus (sp.3 w3a1) 53 d1m3ua_ not modelled 93.5 16 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Ketopantoate hydroxymethyltransferase PanB 54 c9rubB_ not modelled 93.2 18 PDB header:lyase(carbon-carbon) Chain: B: PDB Molecule:ribulose-1,5-bisphosphate carboxylase; PDBTitle: crystal structure of activated ribulose-1,5-bisphosphate2 carboxylase complexed with its substrate, ribulose-1,5-3 bisphosphate 55 c1yadD_ not modelled 92.5 30 PDB header:transcription Chain: D: PDB Molecule:regulatory protein teni; PDBTitle: structure of teni from bacillus subtilis 56 c1bwvA_ not modelled 92.3 22 PDB header:lyase Chain: A: PDB Molecule:protein (ribulose bisphosphate carboxylase); PDBTitle: activated ribulose 1,5-bisphosphate carboxylase/oxygenase (rubisco)2 complexed with the reaction intermediate analogue 2-carboxyarabinitol3 1,5-bisphosphate 57 c3kruC_ not modelled 92.2 18 PDB header:oxidoreductase Chain: C: PDB Molecule:nadh:flavin oxidoreductase/nadh oxidase; PDBTitle: crystal structure of the thermostable old yellow enzyme from2 thermoanaerobacter pseudethanolicus e39 58 d1wa3a1 not modelled 91.9 19 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 59 c2qjhH_ not modelled 91.3 18 PDB header:lyase Chain: H: PDB Molecule:putative aldolase mj0400; PDBTitle: m. jannaschii adh synthase covalently bound to2 dihydroxyacetone phosphate 60 c3k30B_ not modelled 91.1 19 PDB header:oxidoreductase Chain: B: PDB Molecule:histamine dehydrogenase; PDBTitle: histamine dehydrogenase from nocardiodes simplex 61 c2qiwA_ not modelled 91.0 22 PDB header:transferase Chain: A: PDB Molecule:pep phosphonomutase; PDBTitle: crystal structure of a putative phosphoenolpyruvate phosphonomutase2 (ncgl1015, cgl1060) from corynebacterium glutamicum atcc 13032 at3 1.80 a resolution 62 d2czda1 not modelled 91.0 29 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Decarboxylase 63 c2vlbC_ not modelled 90.7 22 PDB header:lyase Chain: C: PDB Molecule:arylmalonate decarboxylase; PDBTitle: structure of unliganded arylmalonate decarboxylase 64 d1ujqa_ not modelled 90.6 23 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 65 d1xcfa_ not modelled 90.5 17 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 66 c3gkaB_ not modelled 90.0 19 PDB header:oxidoreductase Chain: B: PDB Molecule:n-ethylmaleimide reductase; PDBTitle: crystal structure of n-ethylmaleimidine reductase from2 burkholderia pseudomallei 67 d1s2wa_ not modelled 89.0 19 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 68 c1zfjA_ not modelled 88.3 18 PDB header:oxidoreductase Chain: A: PDB Molecule:inosine monophosphate dehydrogenase; PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes 69 c3lerA_ not modelled 87.9 15 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 campylobacter jejuni subsp. jejuni nctc 11168 70 c2y7eA_ not modelled 87.7 22 PDB header:lyase Chain: A: PDB Molecule:3-keto-5-aminohexanoate cleavage enzyme; PDBTitle: crystal structure of the 3-keto-5-aminohexanoate cleavage enzyme2 (kce) from candidatus cloacamonas acidaminovorans (tetragonal form) 71 d3bofa2 not modelled 87.6 20 Fold:TIM beta/alpha-barrel Superfamily:Homocysteine S-methyltransferase Family:Homocysteine S-methyltransferase 72 c3chvA_ not modelled 86.9 16 PDB header:metal binding protein Chain: A: PDB Molecule:prokaryotic domain of unknown function (duf849) with a tim PDBTitle: crystal structure of a prokaryotic domain of unknown function (duf849)2 member (spoa0042) from silicibacter pomeroyi dss-3 at 1.45 a3 resolution 73 c3cixA_ not modelled 86.9 17 PDB header:adomet binding protein Chain: A: PDB Molecule:fefe-hydrogenase maturase; PDBTitle: x-ray structure of the [fefe]-hydrogenase maturase hyde from2 thermotoga maritima in complex with thiocyanate 74 c3bolB_ not modelled 84.8 19 PDB header:transferase Chain: B: PDB Molecule:5-methyltetrahydrofolate s-homocysteine PDBTitle: cobalamin-dependent methionine synthase (1-566) from2 thermotoga maritima complexed with zn2+ 75 d1h5ya_ not modelled 84.8 24 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Histidine biosynthesis enzymes 76 c3js3C_ not modelled 84.6 21 PDB header:lyase Chain: C: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: crystal structure of type i 3-dehydroquinate dehydratase (arod) from2 clostridium difficile with covalent reaction intermediate 77 c3lyeA_ not modelled 84.5 11 PDB header:hydrolase Chain: A: PDB Molecule:oxaloacetate acetyl hydrolase; PDBTitle: crystal structure of oxaloacetate acetylhydrolase 78 c1ydoC_ not modelled 84.2 23 PDB header:lyase Chain: C: PDB Molecule:hmg-coa lyase; PDBTitle: crystal structure of the bacillis subtilis hmg-coa lyase, northeast2 structural genomics target sr181. 79 c2hjpA_ not modelled 84.1 11 PDB header:hydrolase Chain: A: PDB Molecule:phosphonopyruvate hydrolase; PDBTitle: crystal structure of phosphonopyruvate hydrolase complex with2 phosphonopyruvate and mg++ 80 c3s5oA_ not modelled 83.7 17 PDB header:lyase Chain: A: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase, mitochondrial; PDBTitle: crystal structure of human 4-hydroxy-2-oxoglutarate aldolase bound to2 pyruvate 81 d2a6na1 not modelled 83.6 22 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 82 c3q58A_ not modelled 82.9 22 PDB header:isomerase Chain: A: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase; PDBTitle: structure of n-acetylmannosamine-6-phosphate epimerase from salmonella2 enterica 83 d1gqna_ not modelled 81.4 21 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 84 c3no5C_ not modelled 80.9 14 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a pfam duf849 domain containing protein2 (reut_a1631) from ralstonia eutropha jmp134 at 1.90 a resolution 85 c3ih1A_ not modelled 80.5 19 PDB header:lyase Chain: A: PDB Molecule:methylisocitrate lyase; PDBTitle: crystal structure of carboxyvinyl-carboxyphosphonate phosphorylmutase2 from bacillus anthracis 86 d1vyra_ not modelled 79.4 14 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 87 c2ekcA_ not modelled 79.0 17 PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5 88 d1z41a1 not modelled 78.9 19 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 89 c3eb2A_ not modelled 78.7 22 PDB header:lyase Chain: A: PDB Molecule:putative dihydrodipicolinate synthetase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 rhodopseudomonas palustris at 2.0a resolution 90 c2infB_ not modelled 78.7 14 PDB header:lyase Chain: B: PDB Molecule:uroporphyrinogen decarboxylase; PDBTitle: crystal structure of uroporphyrinogen decarboxylase from2 bacillus subtilis 91 c1rr2A_ not modelled 76.9 25 PDB header:transferase Chain: A: PDB Molecule:transcarboxylase 5s subunit; PDBTitle: propionibacterium shermanii transcarboxylase 5s subunit bound to 2-2 ketobutyric acid 92 c3s1vD_ not modelled 76.4 32 PDB header:transferase Chain: D: PDB Molecule:probable transaldolase; PDBTitle: transaldolase from thermoplasma acidophilum in complex with d-fructose2 6-phosphate schiff-base intermediate 93 c1ydnA_ not modelled 76.1 21 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of the hmg-coa lyase from brucella melitensis,2 northeast structural genomics target lr35. 94 d1km4a_ not modelled 76.0 29 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Decarboxylase 95 d1xxxa1 not modelled 76.0 26 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 96 c3o63B_ not modelled 75.2 30 PDB header:transferase Chain: B: PDB Molecule:probable thiamine-phosphate pyrophosphorylase; PDBTitle: crystal structure of thiamin phosphate synthase from mycobacterium2 tuberculosis 97 d1gwja_ not modelled 75.1 14 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 98 d1o5ka_ not modelled 72.5 16 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 99 d1lt7a_ not modelled 71.8 20 Fold:TIM beta/alpha-barrel Superfamily:Homocysteine S-methyltransferase Family:Homocysteine S-methyltransferase 100 c3dz1A_ not modelled 71.8 11 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 rhodopseudomonas palustris at 1.87a resolution 101 c3b8iF_ not modelled 70.9 20 PDB header:lyase Chain: F: PDB Molecule:pa4872 oxaloacetate decarboxylase; PDBTitle: crystal structure of oxaloacetate decarboxylase from pseudomonas2 aeruginosa (pa4872) in complex with oxalate and mg2+. 102 c3na8A_ not modelled 70.9 21 PDB header:lyase Chain: A: PDB Molecule:putative dihydrodipicolinate synthetase; PDBTitle: crystal structure of a putative dihydrodipicolinate synthetase from2 pseudomonas aeruginosa 103 c3e96B_ not modelled 70.1 25 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 bacillus clausii 104 c1x1oC_ not modelled 69.5 23 PDB header:transferase Chain: C: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of project id tt0268 from thermus thermophilus hb8 105 c3d0cB_ not modelled 69.5 23 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 oceanobacillus iheyensis at 1.9 a resolution 106 c3qfeB_ not modelled 68.7 19 PDB header:lyase Chain: B: PDB Molecule:putative dihydrodipicolinate synthase family protein; PDBTitle: crystal structures of a putative dihydrodipicolinate synthase family2 protein from coccidioides immitis 107 d1qopa_ not modelled 67.5 21 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 108 d1umya_ not modelled 67.4 20 Fold:TIM beta/alpha-barrel Superfamily:Homocysteine S-methyltransferase Family:Homocysteine S-methyltransferase 109 d1l6wa_ not modelled 66.6 27 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 110 d1dvja_ not modelled 66.4 37 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Decarboxylase 111 c3c6cA_ not modelled 66.4 12 PDB header:hydrolase Chain: A: PDB Molecule:3-keto-5-aminohexanoate cleavage enzyme; PDBTitle: crystal structure of a putative 3-keto-5-aminohexanoate cleavage2 enzyme (reut_c6226) from ralstonia eutropha jmp134 at 1.72 a3 resolution 112 d1ajza_ not modelled 66.2 24 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 113 c2ehhE_ not modelled 66.0 23 PDB header:lyase Chain: E: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 aquifex aeolicus 114 c2yr1B_ not modelled 65.9 19 PDB header:lyase Chain: B: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: crystal structure of 3-dehydroquinate dehydratase from geobacillus2 kaustophilus hta426 115 c2v9dB_ not modelled 65.5 21 PDB header:lyase Chain: B: PDB Molecule:yage; PDBTitle: crystal structure of yage, a prophage protein belonging to2 the dihydrodipicolinic acid synthase family from e. coli3 k12 116 c3ct7E_ not modelled 64.8 17 PDB header:isomerase Chain: E: PDB Molecule:d-allulose-6-phosphate 3-epimerase; PDBTitle: crystal structure of d-allulose 6-phosphate 3-epimerase2 from escherichia coli k-12 117 c2yw3E_ not modelled 64.8 24 PDB header:lyase Chain: E: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase/2-deydro-3- PDBTitle: crystal structure analysis of the 4-hydroxy-2-oxoglutarate aldolase/2-2 deydro-3-deoxyphosphogluconate aldolase from tthb1 118 d1q45a_ not modelled 64.6 16 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 119 d1f74a_ not modelled 64.2 18 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 120 d1icpa_ not modelled 64.1 10 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0