Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	E	S	L	A	S	L	Y	K	N	H	I	A	T	L	Q	E	R	T	R	D	A	L	A	R	F	K	L	D	A	L	L	I	H	S	G	E	L	F	N	V	F	L	D	D	H	P	Y	P	F	K	V	N	P	Q	F	K	A	W	V
Secondary structure
SS confidence
Disorder		?	?	?	?																							?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	V	T	Q	V	P	N	C	W	L	L	V	D	G	V	N	K	P	K	L	W	F	Y	L	P	V	D	Y	W	H	N	V	E	P	L	P	T	S	F	W	T	E	D	V	E	V	I	A	L	P	K	A	D	G	I	G	S	L	L	P
Secondary structure
SS confidence
Disorder																															?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	A	R	G	N	I	G	Y	I	G	P	V	P	E	R	A	L	Q	L	G	I	E	A	S	N	I	N	P	K	G	V	I	D	Y	L	H	Y	Y	R	S	F	K	T	E	Y	E	L	A	C	M	R	E	A	Q	K	M	A	V	N	G
Secondary structure
SS confidence
Disorder																								?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		H	R	A	A	E	E	A	F	R	S	G	M	S	E	F	D	I	N	I	A	Y	L	T	A	T	G	H	R	D	T	D	V	P	Y	S	N	I	V	A	L	N	E	H	A	A	V	L	H	Y	T	K	L	D	H	Q	A	P	E	E	M
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		R	S	F	L	L	D	A	G	A	E	Y	N	G	Y	A	A	D	L	T	R	T	W	S	A	K	S	D	N	D	Y	A	Q	L	V	K	D	V	N	D	E	Q	L	A	L	I	A	T	M	K	A	G	V	S	Y	V	D	Y	H	I	Q
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		F	H	Q	R	I	A	K	L	L	R	K	H	Q	I	I	T	D	M	S	E	E	A	M	V	E	N	D	L	T	G	P	F	M	P	H	G	I	G	H	P	L	G	L	Q	V	H	D	V	A	G	F	M	Q	D	D	S	G	T	H	L
Secondary structure
SS confidence
Disorder																																																						?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		A	A	P	A	K	Y	P	Y	L	R	C	T	R	I	L	Q	P	G	M	V	L	T	I	E	P	G	I	Y	F	I	E	S	L	L	A	P	W	R	E	G	Q	F	S	K	H	F	N	W	Q	K	I	E	A	L	K	P	F	G	G	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.
Sequence		R	I	E	D	N	V	V	I	H	E	N	N	V	E	N	M	T	R	D	L	K	L	A
Secondary structure
SS confidence
Disorder																					?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3l24 chain A Region: 1 - 442 Aligned: 424 Modelled: 427 Confidence: 100.0% Identity: 51% PDB header:hydrolase Chain: A: PDB Molecule:xaa-pro dipeptidase; PDBTitle: crystal structure of the nerve agent degrading2 organophosphate anhydrolase/prolidase in complex with3 inhibitors Phyre2 PDB 2okn chain B Region: 1 - 441 Aligned: 436 Modelled: 441 Confidence: 100.0% Identity: 29% PDB header:hydrolase Chain: B: PDB Molecule:xaa-pro dipeptidase; PDBTitle: crystal strcture of human prolidase Phyre2 PDB 1w7v chain D Region: 5 - 443 Aligned: 401 Modelled: 406 Confidence: 100.0% Identity: 25% PDB header:hydrolase Chain: D: PDB Molecule:xaa-pro aminopeptidase; PDBTitle: znmg substituted aminopeptidase p from e. coli Phyre2 PDB 3ig4 chain E Region: 5 - 442 Aligned: 377 Modelled: 393 Confidence: 100.0% Identity: 22% PDB header:hydrolase Chain: E: PDB Molecule:xaa-pro aminopeptidase; PDBTitle: structure of a putative aminopeptidase p from bacillus anthracis Phyre2 PDB 3cb5 chain A Region: 9 - 441 Aligned: 383 Modelled: 385 Confidence: 100.0% Identity: 15% PDB header:transcription Chain: A: PDB Molecule:fact complex subunit spt16; PDBTitle: crystal structure of the s. pombe peptidase homology domain of fact2 complex subunit spt16 (form a) Phyre2 PDB 1chm chain A Region: 9 - 441 Aligned: 361 Modelled: 377 Confidence: 100.0% Identity: 21% PDB header:creatinase Chain: A: PDB Molecule:creatine amidinohydrolase; PDBTitle: enzymatic mechanism of creatine amidinohydrolase as deduced2 from crystal structures Phyre2 PDB 3ctz chain A Region: 12 - 434 Aligned: 354 Modelled: 354 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:xaa-pro aminopeptidase 1; PDBTitle: structure of human cytosolic x-prolyl aminopeptidase Phyre2 PDB 2how chain B Region: 15 - 441 Aligned: 346 Modelled: 367 Confidence: 100.0% Identity: 25% PDB header:hydrolase Chain: B: PDB Molecule:356aa long hypothetical dipeptidase; PDBTitle: dipeptidase (ph0974) from pyrococcus horikoshii ot3 Phyre2 PDB 1wy2 chain B Region: 14 - 441 Aligned: 341 Modelled: 351 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: B: PDB Molecule:xaa-pro dipeptidase; PDBTitle: crystal structure of the prolidase from pyrococcus horikoshii ot3 Phyre2 PDB 2zsg chain B Region: 21 - 441 Aligned: 344 Modelled: 349 Confidence: 100.0% Identity: 22% PDB header:hydrolase Chain: B: PDB Molecule:aminopeptidase p, putative; PDBTitle: crystal structure of x-pro aminopeptidase from thermotoga maritima2 msb8 Phyre2 PDB 3q6d chain A Region: 13 - 441 Aligned: 344 Modelled: 347 Confidence: 100.0% Identity: 22% PDB header:viral protein Chain: A: PDB Molecule:proline dipeptidase; PDBTitle: xaa-pro dipeptidase from bacillus anthracis. Phyre2 PDB 3bit chain A Region: 5 - 441 Aligned: 373 Modelled: 380 Confidence: 100.0% Identity: 16% PDB header:transcription Chain: A: PDB Molecule:fact complex subunit spt16; PDBTitle: crystal structure of yeast spt16 n-terminal domain Phyre2 PDB 2g6p chain A Region: 158 - 443 Aligned: 245 Modelled: 266 Confidence: 100.0% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase 1; PDBTitle: crystal structure of truncated (delta 1-89) human methionine2 aminopeptidase type 1 in complex with pyridyl pyrimidine derivative Phyre2 PDB 2gz5 chain A Region: 158 - 443 Aligned: 245 Modelled: 266 Confidence: 100.0% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase 1; PDBTitle: human type 1 methionine aminopeptidase in complex with ovalicin at 1.12 ang Phyre2 PDB 3s6b chain A Region: 159 - 443 Aligned: 244 Modelled: 265 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase; PDBTitle: crystal structure of methionine aminopeptidase 1b from plasmodium2 falciparum, pf10_0150 Phyre2 PDB 1yj3 chain A Region: 158 - 438 Aligned: 240 Modelled: 261 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase; PDBTitle: crystal structure analysis of product bound methionine2 aminopeptidase type 1c from mycobacterium tuberculosis Phyre2 PDB 3tav chain A Region: 158 - 440 Aligned: 249 Modelled: 269 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase; PDBTitle: crystal structure of a methionine aminopeptidase from mycobacterium2 abscessus Phyre2 PDB 1o0x chain A Region: 158 - 439 Aligned: 242 Modelled: 262 Confidence: 100.0% Identity: 20% Fold: Creatinase/aminopeptidase Superfamily: Creatinase/aminopeptidase Family: Creatinase/aminopeptidase Phyre2 PDB 2gg2 chain A domain 1 Region: 160 - 441 Aligned: 242 Modelled: 262 Confidence: 100.0% Identity: 19% Fold: Creatinase/aminopeptidase Superfamily: Creatinase/aminopeptidase Family: Creatinase/aminopeptidase Phyre2 PDB 2v3z chain A domain 2 Region: 163 - 443 Aligned: 246 Modelled: 249 Confidence: 100.0% Identity: 33% Fold: Creatinase/aminopeptidase Superfamily: Creatinase/aminopeptidase Family: Creatinase/aminopeptidase Phyre2 1 c3l24A_ 2 c2oknB_ 3 c1w7vD_ 4 c3ig4E_ 5 c3cb5A_ 6 c1chmA_ 7 c3ctzA_ 8 c2howB_ 9 c1wy2B_ 10 c2zsgB_ 11 c3q6dA_ 12 c3bitA_ 13 c2g6pA_ 14 c2gz5A_ 15 c3s6bA_ 16 c1yj3A_ 17 c3tavA_ 18 d1o0xa_ 19 d2gg2a1 20 d2v3za2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3l24A_ 100.0 51 PDB header:hydrolase Chain: A: PDB Molecule:xaa-pro dipeptidase; PDBTitle: crystal structure of the nerve agent degrading2 organophosphate anhydrolase/prolidase in complex with3 inhibitors 2 c2oknB_ 100.0 29 PDB header:hydrolase Chain: B: PDB Molecule:xaa-pro dipeptidase; PDBTitle: crystal strcture of human prolidase 3 c1w7vD_ 100.0 25 PDB header:hydrolase Chain: D: PDB Molecule:xaa-pro aminopeptidase; PDBTitle: znmg substituted aminopeptidase p from e. coli 4 c3ig4E_ 100.0 22 PDB header:hydrolase Chain: E: PDB Molecule:xaa-pro aminopeptidase; PDBTitle: structure of a putative aminopeptidase p from bacillus anthracis 5 c3cb5A_ 100.0 15 PDB header:transcription Chain: A: PDB Molecule:fact complex subunit spt16; PDBTitle: crystal structure of the s. pombe peptidase homology domain of fact2 complex subunit spt16 (form a) 6 c1chmA_ 100.0 21 PDB header:creatinase Chain: A: PDB Molecule:creatine amidinohydrolase; PDBTitle: enzymatic mechanism of creatine amidinohydrolase as deduced2 from crystal structures 7 c3ctzA_ 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:xaa-pro aminopeptidase 1; PDBTitle: structure of human cytosolic x-prolyl aminopeptidase 8 c2howB_ 100.0 25 PDB header:hydrolase Chain: B: PDB Molecule:356aa long hypothetical dipeptidase; PDBTitle: dipeptidase (ph0974) from pyrococcus horikoshii ot3 9 c1wy2B_ 100.0 23 PDB header:hydrolase Chain: B: PDB Molecule:xaa-pro dipeptidase; PDBTitle: crystal structure of the prolidase from pyrococcus horikoshii ot3 10 c2zsgB_ 100.0 22 PDB header:hydrolase Chain: B: PDB Molecule:aminopeptidase p, putative; PDBTitle: crystal structure of x-pro aminopeptidase from thermotoga maritima2 msb8 11 c3q6dA_ 100.0 22 PDB header:viral protein Chain: A: PDB Molecule:proline dipeptidase; PDBTitle: xaa-pro dipeptidase from bacillus anthracis. 12 c3bitA_ 100.0 16 PDB header:transcription Chain: A: PDB Molecule:fact complex subunit spt16; PDBTitle: crystal structure of yeast spt16 n-terminal domain 13 c2g6pA_ 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase 1; PDBTitle: crystal structure of truncated (delta 1-89) human methionine2 aminopeptidase type 1 in complex with pyridyl pyrimidine derivative 14 c2gz5A_ 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase 1; PDBTitle: human type 1 methionine aminopeptidase in complex with ovalicin at 1.12 ang 15 c3s6bA_ 100.0 19 PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase; PDBTitle: crystal structure of methionine aminopeptidase 1b from plasmodium2 falciparum, pf10_0150 16 c1yj3A_ 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase; PDBTitle: crystal structure analysis of product bound methionine2 aminopeptidase type 1c from mycobacterium tuberculosis 17 c3tavA_ 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase; PDBTitle: crystal structure of a methionine aminopeptidase from mycobacterium2 abscessus 18 d1o0xa_ 100.0 20 Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase 19 d2gg2a1 100.0 19 Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase 20 d2v3za2 100.0 33 Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase 21 c3mx6A_ not modelled 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase; PDBTitle: crystal structure of methionine aminopeptidase from rickettsia2 prowazekii bound to methionine 22 d1qxya_ not modelled 100.0 20 Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase 23 d1chma2 not modelled 100.0 23 Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase 24 c1kp0B_ not modelled 100.0 18 PDB header:hydrolase Chain: B: PDB Molecule:creatine amidinohydrolase; PDBTitle: the crystal structure analysis of creatine amidinohydrolase2 from actinobacillus 25 d1pv9a2 not modelled 100.0 28 Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase 26 d1b6aa2 not modelled 100.0 14 Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase 27 d1xgsa2 not modelled 100.0 21 Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase 28 c2v6cA_ not modelled 100.0 14 PDB header:transcription regulator Chain: A: PDB Molecule:proliferation-associated protein 2g4; PDBTitle: crystal structure of erbb3 binding protein 1 (ebp1) 29 c2q8kA_ not modelled 100.0 14 PDB header:transcription Chain: A: PDB Molecule:proliferation-associated protein 2g4; PDBTitle: the crystal structure of ebp1 30 c1xgnB_ not modelled 100.0 21 PDB header:aminopeptidase Chain: B: PDB Molecule:methionine aminopeptidase; PDBTitle: methionine aminopeptidase from hyperthermophile pyrococcus2 furiosus 31 d1kp0a2 not modelled 100.0 22 Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase 32 c1b6aA_ not modelled 100.0 16 PDB header:angiogenesis inhibitor Chain: A: PDB Molecule:methionine aminopeptidase; PDBTitle: human methionine aminopeptidase 2 complexed with tnp-470 33 c3fm3B_ not modelled 100.0 17 PDB header:hydrolase Chain: B: PDB Molecule:methionine aminopeptidase 2; PDBTitle: crystal structure of an encephalitozoon cuniculi methionine2 aminopeptidase type 2 34 c1yw7A_ not modelled 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase 2; PDBTitle: h-metap2 complexed with a444148 35 d2v3za1 not modelled 99.6 15 Fold:Ribonuclease H-like motif Superfamily:Creatinase/prolidase N-terminal domain Family:Creatinase/prolidase N-terminal domain 36 d1chma1 not modelled 99.0 17 Fold:Ribonuclease H-like motif Superfamily:Creatinase/prolidase N-terminal domain Family:Creatinase/prolidase N-terminal domain 37 c3pn9C_ not modelled 99.0 12 PDB header:hydrolase Chain: C: PDB Molecule:proline dipeptidase; PDBTitle: crystal structure of a proline dipeptidase from streptococcus2 pneumoniae tigr4 38 c3i7mA_ not modelled 98.8 10 PDB header:hydrolase Chain: A: PDB Molecule:xaa-pro dipeptidase; PDBTitle: n-terminal domain of xaa-pro dipeptidase from lactobacillus brevis. 39 c3il0B_ not modelled 98.8 13 PDB header:hydrolase Chain: B: PDB Molecule:aminopeptidase p; xaa-pro aminopeptidase; PDBTitle: the crystal structure of the aminopeptidase p,xaa-pro aminopeptidase2 from streptococcus thermophilus 40 c3oooA_ not modelled 98.7 12 PDB header:hydrolase Chain: A: PDB Molecule:proline dipeptidase; PDBTitle: the structure of a proline dipeptidase from streptococcus agalactiae2 2603v 41 c3ovkD_ not modelled 98.7 13 PDB header:hydrolase Chain: D: PDB Molecule:aminopeptidase p, xaa-pro dipeptidase; PDBTitle: crystal structure of an xxa-pro aminopeptidase from streptococcus2 pyogenes 42 c3o5vA_ not modelled 98.5 11 PDB header:hydrolase Chain: A: PDB Molecule:x-pro dipeptidase; PDBTitle: the crystal structure of the creatinase/prolidase n-terminal domain of2 an x-pro dipeptidase from streptococcus pyogenes to 1.85a 43 d1pv9a1 not modelled 98.3 16 Fold:Ribonuclease H-like motif Superfamily:Creatinase/prolidase N-terminal domain Family:Creatinase/prolidase N-terminal domain 44 c3qocD_ not modelled 98.2 15 PDB header:hydrolase Chain: D: PDB Molecule:putative metallopeptidase; PDBTitle: crystal structure of n-terminal domain (creatinase/prolidase like2 domain) of putative metallopeptidase from corynebacterium diphtheriae 45 d1kp0a1 not modelled 89.8 26 Fold:Ribonuclease H-like motif Superfamily:Creatinase/prolidase N-terminal domain Family:Creatinase/prolidase N-terminal domain 46 d1wsaa_ not modelled 63.1 20 Fold:Glutaminase/Asparaginase Superfamily:Glutaminase/Asparaginase Family:Glutaminase/Asparaginase 47 d1o7ja_ not modelled 53.8 19 Fold:Glutaminase/Asparaginase Superfamily:Glutaminase/Asparaginase Family:Glutaminase/Asparaginase 48 d1agxa_ not modelled 53.8 18 Fold:Glutaminase/Asparaginase Superfamily:Glutaminase/Asparaginase Family:Glutaminase/Asparaginase 49 c3mpbA_ not modelled 53.6 24 PDB header:isomerase Chain: A: PDB Molecule:sugar isomerase; PDBTitle: z5688 from e. coli o157:h7 bound to fructose 50 c2wltA_ not modelled 48.1 15 PDB header:hydrolase Chain: A: PDB Molecule:l-asparaginase; PDBTitle: the crystal structure of helicobacter pylori l-asparaginase2 at 1.4 a resolution 51 c2d6fA_ not modelled 37.1 10 PDB header:ligase/rna Chain: A: PDB Molecule:glutamyl-trna(gln) amidotransferase subunit d; PDBTitle: crystal structure of glu-trna(gln) amidotransferase in the2 complex with trna(gln) 52 d4pgaa_ not modelled 36.9 21 Fold:Glutaminase/Asparaginase Superfamily:Glutaminase/Asparaginase Family:Glutaminase/Asparaginase 53 c1utyA_ not modelled 34.3 30 PDB header:viral protein Chain: A: PDB Molecule:non-structural protein 2; PDBTitle: crystal structure of the rna binding domain of bluetongue2 virus non-structural protein 2(ns2) 54 d1utya_ not modelled 34.3 30 Fold:BTV NS2-like ssRNA-binding domain Superfamily:BTV NS2-like ssRNA-binding domain Family:BTV NS2-like ssRNA-binding domain 55 c2c5qE_ not modelled 33.4 9 PDB header:structural genomics,unknown function Chain: E: PDB Molecule:rraa-like protein yer010c; PDBTitle: crystal structure of yeast yer010cp 56 d2d6fa2 not modelled 32.8 11 Fold:Glutaminase/Asparaginase Superfamily:Glutaminase/Asparaginase Family:Glutaminase/Asparaginase 57 d2olra1 not modelled 32.1 18 Fold:PEP carboxykinase-like Superfamily:PEP carboxykinase-like Family:PEP carboxykinase C-terminal domain 58 c1zq1B_ not modelled 31.5 11 PDB header:lyase Chain: B: PDB Molecule:glutamyl-trna(gln) amidotransferase subunit d; PDBTitle: structure of gatde trna-dependent amidotransferase from2 pyrococcus abyssi 59 c3nxkE_ not modelled 29.2 16 PDB header:hydrolase Chain: E: PDB Molecule:cytoplasmic l-asparaginase; PDBTitle: crystal structure of probable cytoplasmic l-asparaginase from2 campylobacter jejuni 60 c2y0oA_ not modelled 28.3 22 PDB header:isomerase Chain: A: PDB Molecule:probable d-lyxose ketol-isomerase; PDBTitle: the structure of a d-lyxose isomerase from the sigmab2 regulon of bacillus subtilis 61 c2nyuA_ not modelled 27.4 18 PDB header:transferase Chain: A: PDB Molecule:putative ribosomal rna methyltransferase 2; PDBTitle: crystal structure of human ftsj homolog 2 (e.coli) protein2 in complex with s-adenosylmethionine 62 d1j3ba1 not modelled 26.8 25 Fold:PEP carboxykinase-like Superfamily:PEP carboxykinase-like Family:PEP carboxykinase C-terminal domain 63 d1xuca1 not modelled 26.5 58 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 64 d1qiba_ not modelled 25.5 50 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 65 d1i76a_ not modelled 25.4 58 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 66 d1cxva_ not modelled 24.9 58 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 67 d1hfca_ not modelled 23.2 58 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 68 d1hy7a_ not modelled 22.7 57 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 69 c2cltB_ not modelled 20.3 64 PDB header:hydrolase Chain: B: PDB Molecule:interstitial collagenase; PDBTitle: crystal structure of the active form (full-length) of human2 fibroblast collagenase. 70 c3nojA_ not modelled 19.2 11 PDB header:lyase Chain: A: PDB Molecule:4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate PDBTitle: the structure of hmg/cha aldolase from the protocatechuate degradation2 pathway of pseudomonas putida 71 c1ylhA_ not modelled 18.0 22 PDB header:lyase Chain: A: PDB Molecule:phosphoenolpyruvate carboxykinase; PDBTitle: crystal structure of phosphoenolpyruvate carboxykinase from2 actinobaccilus succinogenes in complex with manganese and3 pyruvate 72 d2i47a1 not modelled 16.3 43 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:TNF-alpha converting enzyme, TACE, catalytic domain 73 d1eaka2 not modelled 16.1 50 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 74 d1rm8a_ not modelled 15.9 50 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 75 c2i47A_ not modelled 15.5 40 PDB header:hydrolase Chain: A: PDB Molecule:adam 17; PDBTitle: crystal structure of catalytic domain of tace with inhibitor 76 c1yp1A_ not modelled 15.2 47 PDB header:hydrolase Chain: A: PDB Molecule:fii; PDBTitle: crystal structure of a non-hemorrhagic fibrin(ogen)olytic2 metalloproteinase from venom of agkistrodon acutus 77 d1bqqm_ not modelled 14.5 60 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 78 c3k7lA_ not modelled 14.4 47 PDB header:hydrolase Chain: A: PDB Molecule:atragin; PDBTitle: structures of two elapid snake venom metalloproteases with2 distinct activities highlight the disulfide patterns in the3 d domain of adamalysin family proteins 79 c3edhA_ not modelled 14.4 42 PDB header:hydrolase Chain: A: PDB Molecule:bone morphogenetic protein 1; PDBTitle: crystal structure of bone morphogenetic protein 1 protease2 domain in complex with partially bound dmso 80 d1r55a_ not modelled 14.2 67 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 81 d2ovxa1 not modelled 14.0 60 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 82 d1q3aa_ not modelled 14.0 60 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 83 c2erpA_ not modelled 14.0 47 PDB header:toxin Chain: A: PDB Molecule:vascular apoptosis-inducing protein 1; PDBTitle: crystal structure of vascular apoptosis-inducing protein-1(inhibitor-2 bound form) 84 c1slmA_ not modelled 13.8 70 PDB header:hydrolase Chain: A: PDB Molecule:stromelysin-1; PDBTitle: crystal structure of fibroblast stromelysin-1: the c-truncated human2 proenzyme 85 c3jr1A_ not modelled 13.8 6 PDB header:transferase Chain: A: PDB Molecule:putative fructosamine-3-kinase; PDBTitle: crystal structure of putative fructosamine-3-kinase2 (yp_719053.1) from haemophilus somnus 129pt at 2.32 a3 resolution 86 d1wnia_ not modelled 13.7 57 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 87 d1atla_ not modelled 13.6 50 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 88 d1fbla2 not modelled 13.5 60 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 89 c2xs4A_ not modelled 13.4 50 PDB header:hydrolase Chain: A: PDB Molecule:karilysin protease; PDBTitle: structure of karilysin catalytic mmp domain in complex with2 magnesium 90 c2dw1B_ not modelled 13.4 47 PDB header:apoptosis, toxin Chain: B: PDB Molecule:catrocollastatin; PDBTitle: crystal structure of vap2 from crotalus atrox venom (form 2-2 crystal) 91 d1nd1a_ not modelled 13.4 47 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 92 d1hova_ not modelled 13.3 50 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 93 d1cgla_ not modelled 13.2 60 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 94 c2rjqA_ not modelled 13.2 56 PDB header:hydrolase Chain: A: PDB Molecule:adamts-5; PDBTitle: crystal structure of adamts5 with inhibitor bound 95 c3lqbA_ not modelled 13.1 42 PDB header:hydrolase Chain: A: PDB Molecule:loc792177 protein; PDBTitle: crystal structure of the hatching enzyme zhe1 from the zebrafish danio2 rerio 96 d1y93a1 not modelled 13.0 58 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 97 d1bswa_ not modelled 13.0 35 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 98 d4aiga_ not modelled 12.8 47 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 99 d1hv5a_ not modelled 12.4 70 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0