Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	S	F	D	Y	L	K	T	A	I	K	Q	Q	G	C	T	L	Q	Q	V	A	D	A	S	G	M	T	K	G	Y	L	S	Q	L	L	N	A	K	I	K	S	P	S	A	Q	K	L	E	A	L	H	R	F	L	G	L	E	F	P
Secondary structure
SS confidence
Disorder		?	?	?	?										?	?							?	?	?	?		?											?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	Q	K	K	T	I	G	V	V	F	G	K	F	Y	P	L	H	T	G	H	I	Y	L	I	Q	R	A	C	S	Q	V	D	E	L	H	I	I	M	G	F	D	D	T	R	D	R	A	L	F	E	D	S	A	M	S	Q	Q	P	T	V
Secondary structure
SS confidence
Disorder		?																																										?	?	?				?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		P	D	R	L	R	W	L	L	Q	T	F	K	Y	Q	K	N	I	R	I	H	A	F	N	E	E	G	M	E	P	Y	P	H	G	W	D	V	W	S	N	G	I	K	K	F	M	A	E	K	G	I	Q	P	D	L	I	Y	T	S	E	E
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	D	A	P	Q	Y	M	E	H	L	G	I	E	T	V	L	V	D	P	K	R	T	F	M	S	I	S	G	A	Q	I	R	E	N	P	F	R	Y	W	E	Y	I	P	T	E	V	K	P	F	F	V	R	T	V	A	I	L	G	G	E
Secondary structure
SS confidence
Disorder																						?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		S	S	G	K	S	T	L	V	N	K	L	A	N	I	F	N	T	T	S	A	W	E	Y	G	R	D	Y	V	F	S	H	L	G	G	D	E	I	A	L	Q	Y	S	D	Y	D	K	I	A	L	G	H	A	Q	Y	I	D	F	A	V	K
Secondary structure
SS confidence
Disorder																																				?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		Y	A	N	K	V	A	F	I	D	T	D	F	V	T	T	Q	A	F	C	K	K	Y	E	G	R	E	H	P	F	V	Q	A	L	I	D	E	Y	R	F	D	L	V	I	L	L	E	N	N	T	P	W	V	A	D	G	L	R	S	L	G
Secondary structure
SS confidence
Disorder																																																											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410
Sequence		S	S	V	D	R	K	E	F	Q	N	L	L	V	E	M	L	E	E	N	N	I	E	F	V	R	V	E	E	E	D	Y	D	S	R	F	L	R	C	V	E	L	V	R	E	M	M	G	E	Q	R
Secondary structure
SS confidence
Disorder																																																?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1lw7 chain A Region: 63 - 409 Aligned: 336 Modelled: 347 Confidence: 100.0% Identity: 53% PDB header:transferase Chain: A: PDB Molecule:transcriptional regulator nadr; PDBTitle: nadr protein from haemophilus influenzae Phyre2 PDB 1lw7 chain A domain 2 Region: 225 - 409 Aligned: 174 Modelled: 185 Confidence: 100.0% Identity: 56% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nucleotide and nucleoside kinases Phyre2 PDB 1lw7 chain A domain 1 Region: 63 - 224 Aligned: 162 Modelled: 162 Confidence: 100.0% Identity: 51% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Adenylyltransferase Phyre2 PDB 2qjo chain B Region: 63 - 232 Aligned: 159 Modelled: 170 Confidence: 99.9% Identity: 17% PDB header:transferase, hydrolase Chain: B: PDB Molecule:bifunctional nmn adenylyltransferase/nudix hydrolase; PDBTitle: crystal structure of a bifunctional nmn adenylyltransferase/adp ribose2 pyrophosphatase (nadm) complexed with adprp and nad from3 synechocystis sp. Phyre2 PDB 1f9a chain A Region: 67 - 252 Aligned: 159 Modelled: 186 Confidence: 99.9% Identity: 21% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Adenylyltransferase Phyre2 PDB 3f3m chain A Region: 63 - 233 Aligned: 149 Modelled: 156 Confidence: 99.9% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:phosphopantetheine adenylyltransferase; PDBTitle: six crystal structures of two phosphopantetheine2 adenylyltransferases reveal an alternative ligand binding3 mode and an associated structural change Phyre2 PDB 1ej2 chain A Region: 67 - 232 Aligned: 151 Modelled: 166 Confidence: 99.9% Identity: 17% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Adenylyltransferase Phyre2 PDB 1qjc chain A Region: 65 - 235 Aligned: 154 Modelled: 171 Confidence: 99.9% Identity: 17% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Adenylyltransferase Phyre2 PDB 1tfu chain A Region: 65 - 233 Aligned: 151 Modelled: 159 Confidence: 99.9% Identity: 19% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Adenylyltransferase Phyre2 PDB 3ikz chain A Region: 65 - 234 Aligned: 149 Modelled: 160 Confidence: 99.9% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:phosphopantetheine adenylyltransferase; PDBTitle: crystal structure of phosphopantetheine adenylyltransferase from2 burkholderia pseudomallei Phyre2 PDB 1o6b chain A Region: 65 - 233 Aligned: 151 Modelled: 169 Confidence: 99.9% Identity: 18% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Adenylyltransferase Phyre2 PDB 1vlh chain A Region: 66 - 233 Aligned: 151 Modelled: 162 Confidence: 99.9% Identity: 22% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Adenylyltransferase Phyre2 PDB 2r5w chain A Region: 65 - 232 Aligned: 157 Modelled: 168 Confidence: 99.9% Identity: 17% PDB header:hydrolase, transferase Chain: A: PDB Molecule:nicotinamide-nucleotide adenylyltransferase; PDBTitle: crystal structure of a bifunctional nmn2 adenylyltransferase/adp ribose pyrophosphatase from3 francisella tularensis Phyre2 PDB 3op1 chain A Region: 58 - 218 Aligned: 157 Modelled: 161 Confidence: 99.9% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:macrolide-efflux protein; PDBTitle: crystal structure of macrolide-efflux protein sp_1110 from2 streptococcus pneumoniae Phyre2 PDB 3nd5 chain D Region: 64 - 233 Aligned: 147 Modelled: 154 Confidence: 99.9% Identity: 22% PDB header:transferase Chain: D: PDB Molecule:phosphopantetheine adenylyltransferase; PDBTitle: crystal structure of phosphopantetheine adenylyltransferase (ppat)2 from enterococcus faecalis Phyre2 PDB 3nv7 chain A Region: 65 - 232 Aligned: 151 Modelled: 158 Confidence: 99.9% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:phosphopantetheine adenylyltransferase; PDBTitle: crystal structure of h.pylori phosphopantetheine adenylyltransferase2 mutant i4v/n76y Phyre2 PDB 2x0k chain B Region: 58 - 245 Aligned: 186 Modelled: 188 Confidence: 99.9% Identity: 16% PDB header:transferase Chain: B: PDB Molecule:riboflavin biosynthesis protein ribf; PDBTitle: crystal structure of modular fad synthetase from2 corynebacterium ammoniagenes Phyre2 PDB 3e27 chain B Region: 64 - 233 Aligned: 160 Modelled: 170 Confidence: 99.9% Identity: 14% PDB header:transferase Chain: B: PDB Molecule:nicotinate (nicotinamide) nucleotide PDBTitle: nicotinic acid mononucleotide (namn) adenylyltransferase2 from bacillus anthracis: product complex Phyre2 PDB 1od6 chain A Region: 67 - 233 Aligned: 146 Modelled: 154 Confidence: 99.9% Identity: 18% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Adenylyltransferase Phyre2 PDB 1kam chain A Region: 63 - 232 Aligned: 151 Modelled: 156 Confidence: 99.9% Identity: 19% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Adenylyltransferase Phyre2 PDB 1iho chain A Region: 44 - 137 Aligned: 87 Modelled: 87 Confidence: 97.4% Identity: 17% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) Phyre2 1 c1lw7A_ 2 d1lw7a2 3 d1lw7a1 4 c2qjoB_ 5 d1f9aa_ 6 c3f3mA_ 7 d1ej2a_ 8 d1qjca_ 9 d1tfua_ 10 c3ikzA_ 11 d1o6ba_ 12 d1vlha_ 13 c2r5wA_ 14 c3op1A_ 15 c3nd5D_ 16 c3nv7A_ 17 c2x0kB_ 18 c3e27B_ 19 d1od6a_ 20 d1kama_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 d1ihoa_ 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499