Email l.a.kelley@imperial.ac.uk Description P04825 Date Thu Jan 5 10:58:23 GMT 2012 Unique Job ID b5a473cc1e035341

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3b37A_ 100.0 100 PDB header:hydrolase Chain: A: PDB Molecule:aminopeptidase n; PDBTitle: crystal structure of e. coli aminopeptidase n in complex with tyrosine 2 c3ebhA_ 100.0 35 PDB header:hydrolase inhibitor Chain: A: PDB Molecule:m1 family aminopeptidase; PDBTitle: structure of the m1 alanylaminopeptidase from malaria complexed with2 bestatin 3 c2gtqA_ 100.0 47 PDB header:hydrolase Chain: A: PDB Molecule:aminopeptidase n; PDBTitle: crystal structure of aminopeptidase n from human pathogen neisseria2 meningitidis 4 c3se6A_ 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:endoplasmic reticulum aminopeptidase 2; PDBTitle: crystal structure of the human endoplasmic reticulum aminopeptidase 2 5 c2xdtA_ 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:endoplasmic reticulum aminopeptidase 1; PDBTitle: crystal structure of the soluble domain of human2 endoplasmic reticulum aminopeptidase 1 erap1 6 c3mdjB_ 100.0 17 PDB header:hydrolase/hydrolase inhibitor Chain: B: PDB Molecule:endoplasmic reticulum aminopeptidase 1; PDBTitle: er aminopeptidase, erap1, bound to the zinc aminopeptidase inhibitor,2 bestatin 7 c1z5hB_ 100.0 19 PDB header:hydrolase Chain: B: PDB Molecule:tricorn protease interacting factor f3; PDBTitle: crystal structures of the tricorn interacting factor f32 from thermoplasma acidophilum 8 c3qnfA_ 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:endoplasmic reticulum aminopeptidase 1; PDBTitle: crystal structure of the open state of human endoplasmic reticulum2 aminopeptidase 1 erap1 9 c3b7uX_ 100.0 24 PDB header:hydrolase Chain: X: PDB Molecule:leukotriene a-4 hydrolase; PDBTitle: leukotriene a4 hydrolase complexed with kelatorphan 10 c3ciaA_ 100.0 21 PDB header:hydrolase Chain: A: PDB Molecule:cold-active aminopeptidase; PDBTitle: crystal structure of cold-aminopeptidase from colwellia2 psychrerythraea 11 c2xpyA_ 100.0 21 PDB header:hydrolase Chain: A: PDB Molecule:leukotriene a-4 hydrolase; PDBTitle: structure of native leukotriene a4 hydrolase from saccharomyces2 cerevisiae 12 d3b7sa3 100.0 24 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Leukotriene A4 hydrolase catalytic domain 13 d3b7sa2 100.0 23 Fold:Leukotriene A4 hydrolase N-terminal domain Superfamily:Leukotriene A4 hydrolase N-terminal domain Family:Leukotriene A4 hydrolase N-terminal domain 14 c3rjoA_ 99.9 12 PDB header:hydrolase Chain: A: PDB Molecule:endoplasmic reticulum aminopeptidase 1; PDBTitle: crystal structure of erap1 peptide binding domain 15 c2vqxA_ 95.2 19 PDB header:hydrolase Chain: A: PDB Molecule:metalloproteinase; PDBTitle: precursor of protealysin, metalloproteinase from serratia2 proteamaculans. 16 d1u4ga_ 95.1 11 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Thermolysin-like 17 d1npca_ 93.7 17 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Thermolysin-like 18 c3cqbB_ 93.3 20 PDB header:hydrolase Chain: B: PDB Molecule:probable protease htpx homolog; PDBTitle: crystal structure of heat shock protein htpx domain from vibrio2 parahaemolyticus rimd 2210633 19 c3nqzB_ 91.8 15 PDB header:hydrolase Chain: B: PDB Molecule:secreted metalloprotease mcp02; PDBTitle: crystal structure of the autoprocessed vibriolysin mcp-02 with e369a2 mutation 20 c3nqxA_ 91.1 15 PDB header:hydrolase Chain: A: PDB Molecule:secreted metalloprotease mcp02; PDBTitle: crystal structure of vibriolysin mcp-02 mature enzyme, a zinc2 metalloprotease from m4 family 21 c3k7nA_ not modelled 89.3 20 PDB header:hydrolase Chain: A: PDB Molecule:k-like; PDBTitle: structures of two elapid snake venom metalloproteases with2 distinct activities highlight the disulfide patterns in the3 d domain of adamalysin family proteins 22 d1bqba_ not modelled 88.6 17 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Thermolysin-like 23 c3k7lA_ not modelled 88.3 16 PDB header:hydrolase Chain: A: PDB Molecule:atragin; PDBTitle: structures of two elapid snake venom metalloproteases with2 distinct activities highlight the disulfide patterns in the3 d domain of adamalysin family proteins 24 c2dw1B_ not modelled 87.5 19 PDB header:apoptosis, toxin Chain: B: PDB Molecule:catrocollastatin; PDBTitle: crystal structure of vap2 from crotalus atrox venom (form 2-2 crystal) 25 c2erpA_ not modelled 86.1 17 PDB header:toxin Chain: A: PDB Molecule:vascular apoptosis-inducing protein 1; PDBTitle: crystal structure of vascular apoptosis-inducing protein-1(inhibitor-2 bound form) 26 d1kjpa_ not modelled 86.0 14 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Thermolysin-like 27 d1r55a_ not modelled 84.4 14 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 28 c3c37B_ not modelled 83.9 15 PDB header:hydrolase Chain: B: PDB Molecule:peptidase, m48 family; PDBTitle: x-ray structure of the putative zn-dependent peptidase q74d82 at the2 resolution 1.7 a. northeast structural genomics consortium target3 gsr143a 29 d4aiga_ not modelled 83.8 14 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 30 c3g5cA_ not modelled 82.1 14 PDB header:membrane protein Chain: A: PDB Molecule:adam 22; PDBTitle: structural and biochemical studies on the ectodomain of human adam22 31 c2e3xA_ not modelled 82.1 15 PDB header:hydrolase, blood clotting, toxin Chain: A: PDB Molecule:coagulation factor x-activating enzyme heavy chain; PDBTitle: crystal structure of russell's viper venom metalloproteinase 32 d1nd1a_ not modelled 79.4 16 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 33 c2rjpC_ not modelled 78.5 14 PDB header:hydrolase Chain: C: PDB Molecule:adamts-4; PDBTitle: crystal structure of adamts4 with inhibitor bound 34 d1quaa_ not modelled 78.1 16 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 35 d1kufa_ not modelled 77.7 13 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 36 d1atla_ not modelled 77.5 13 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 37 d1bswa_ not modelled 77.3 16 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 38 c2rjqA_ not modelled 76.0 19 PDB header:hydrolase Chain: A: PDB Molecule:adamts-5; PDBTitle: crystal structure of adamts5 with inhibitor bound 39 c2y50A_ not modelled 75.5 15 PDB header:hydrolase Chain: A: PDB Molecule:collagenase; PDBTitle: crystal structure of collagenase g from clostridium2 histolyticum at 2.80 angstrom resolution 40 d1wnia_ not modelled 73.4 11 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 41 c2j83B_ not modelled 71.8 26 PDB header:hydrolase Chain: B: PDB Molecule:ulilysin; PDBTitle: ulilysin metalloprotease in complex with batimastat. 42 c1yp1A_ not modelled 70.7 15 PDB header:hydrolase Chain: A: PDB Molecule:fii; PDBTitle: crystal structure of a non-hemorrhagic fibrin(ogen)olytic2 metalloproteinase from venom of agkistrodon acutus 43 c3iukB_ not modelled 70.2 11 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of putative bacterial protein of unknown function2 (duf885, pf05960.1, ) from arthrobacter aurescens tc1, reveals fold3 similar to that of m32 carboxypeptidases 44 c2v4bB_ not modelled 69.1 23 PDB header:hydrolase Chain: B: PDB Molecule:adamts-1; PDBTitle: crystal structure of human adamts-1 catalytic domain and2 cysteine-rich domain (apo-form) 45 c3dtkA_ not modelled 68.7 15 PDB header:gene regulation Chain: A: PDB Molecule:irre protein; PDBTitle: crystal structure of the irre protein, a central regulator2 of dna damage repair in deinococcaceae 46 c3o0yC_ not modelled 67.4 10 PDB header:lipid binding protein Chain: C: PDB Molecule:lipoprotein; PDBTitle: the crystal structure of the putative lipoprotein from colwellia2 psychrerythraea 47 c2i47A_ not modelled 61.9 38 PDB header:hydrolase Chain: A: PDB Molecule:adam 17; PDBTitle: crystal structure of catalytic domain of tace with inhibitor 48 c3lmcA_ not modelled 61.5 19 PDB header:hydrolase Chain: A: PDB Molecule:peptidase, zinc-dependent; PDBTitle: crystal structure of zinc-dependent peptidase from methanocorpusculum2 labreanum (strain z), northeast structural genomics consortium target3 mur16 49 c3b8zB_ not modelled 61.1 23 PDB header:hydrolase Chain: B: PDB Molecule:protein adamts-5; PDBTitle: high resolution crystal structure of the catalytic domain2 of adamts-5 (aggrecanase-2) 50 d2i47a1 not modelled 60.7 38 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:TNF-alpha converting enzyme, TACE, catalytic domain 51 c2qn0A_ not modelled 59.2 21 PDB header:toxin Chain: A: PDB Molecule:neurotoxin; PDBTitle: structure of botulinum neurotoxin serotype c1 light chain2 protease 52 c2xhqA_ not modelled 57.7 18 PDB header:hydrolase Chain: A: PDB Molecule:archaemetzincin; PDBTitle: crystal structure of archaemetzincin (amza) from archaeoglobus2 fulgidus at 1.45 a resolution 53 c1z7hA_ not modelled 57.2 13 PDB header:hydrolase Chain: A: PDB Molecule:tetanus toxin light chain; PDBTitle: 2.3 angstrom crystal structure of tetanus neurotoxin light2 chain 54 d1f83a_ not modelled 56.8 26 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Clostridium neurotoxins, catalytic domain 55 d3btaa3 not modelled 56.4 18 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Clostridium neurotoxins, catalytic domain 56 c3hjlA_ not modelled 54.0 15 PDB header:proton transport Chain: A: PDB Molecule:flagellar motor switch protein flig; PDBTitle: the structure of full-length flig from aquifex aeolicus 57 d1k9xa_ not modelled 53.9 10 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Neurolysin-like 58 c3ka1A_ not modelled 53.4 21 PDB header:chaperone Chain: A: PDB Molecule:rbcx protein; PDBTitle: crystal structure of rbcx from thermosynechococcus elongatus 59 d1epwa3 not modelled 52.9 26 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Clostridium neurotoxins, catalytic domain 60 d2ejqa1 not modelled 49.4 6 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:TTHA0227-like 61 c2o0cB_ not modelled 49.4 18 PDB header:signaling protein Chain: B: PDB Molecule:alr2278 protein; PDBTitle: crystal structure of the h-nox domain from nostoc sp. pcc 71202 complexed to no 62 c3zusD_ not modelled 49.0 18 PDB header:hydrolase/signaling protein Chain: D: PDB Molecule:botulinum neurotoxin type a, synaptosomal-associated PDBTitle: crystal structure of an engineered botulinum neurotoxin2 type a-snare23 derivative, lc-a-snap23-hn-a 63 c2nyyA_ not modelled 48.9 18 PDB header:toxin/immune system Chain: A: PDB Molecule:botulinum neurotoxin type a; PDBTitle: crystal structure of botulinum neurotoxin type a complexed with2 monoclonal antibody cr1 64 d3bona1 not modelled 47.4 18 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Clostridium neurotoxins, catalytic domain 65 c3deeA_ not modelled 47.4 0 PDB header:transcription Chain: A: PDB Molecule:putative regulatory protein; PDBTitle: crystal structure of a putative regulatory protein involved in2 transcription (ngo1945) from neisseria gonorrhoeae fa 1090 at 2.25 a3 resolution 66 d1j7na2 not modelled 47.4 17 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Anthrax toxin lethal factor, N- and C-terminal domains 67 c3zuqA_ not modelled 46.9 26 PDB header:hydrolase Chain: A: PDB Molecule:botulinum neurotoxin type b; PDBTitle: crystal structure of an engineered botulinum neurotoxin2 type b-derivative, lc-b-gs-hn-b 68 d2f22a1 not modelled 46.3 36 Fold:DinB/YfiT-like putative metalloenzymes Superfamily:DinB/YfiT-like putative metalloenzymes Family:DinB-like 69 c1s0bA_ not modelled 45.0 26 PDB header:toxin, hydrolase Chain: A: PDB Molecule:botulinum neurotoxin type b; PDBTitle: crystal structure of botulinum neurotoxin type b at ph 4.0 70 c3pl4A_ not modelled 44.7 12 PDB header:motor protein Chain: A: PDB Molecule:flagellar motor switch protein; PDBTitle: crystal structure of flig (residue 116-343) from h. pylori 71 c3zurA_ not modelled 43.8 13 PDB header:hydrolase/signaling protein Chain: A: PDB Molecule:botulinum neurotoxin type a, synaptosomal-associated PDBTitle: crystal structure of an engineered botulinum neurotoxin2 type a-snare23 derivative, lc0-a-snap25-hn-a 72 c3dl1A_ not modelled 39.0 12 PDB header:hydrolase Chain: A: PDB Molecule:putative metal-dependent hydrolase; PDBTitle: crystal structure of a putative metal-dependent hydrolase2 (yp_001336084.1) from klebsiella pneumoniae subsp. pneumoniae mgh3 78578 at 2.20 a resolution 73 c2y0oA_ not modelled 38.9 14 PDB header:isomerase Chain: A: PDB Molecule:probable d-lyxose ketol-isomerase; PDBTitle: the structure of a d-lyxose isomerase from the sigmab2 regulon of bacillus subtilis 74 c2l0rA_ not modelled 38.7 15 PDB header:hydrolase,toxin Chain: A: PDB Molecule:lethal factor; PDBTitle: conformational dynamics of the anthrax lethal factor catalytic center 75 d1lmla_ not modelled 38.4 19 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Leishmanolysin 76 c3sohB_ not modelled 36.4 26 PDB header:motor protein Chain: B: PDB Molecule:flagellar motor switch protein flig; PDBTitle: architecture of the flagellar rotor 77 d1bqqm_ not modelled 35.5 45 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 78 d2a1jb1 not modelled 34.8 20 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Hef domain-like 79 d1rm8a_ not modelled 32.3 36 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 80 c2xs4A_ not modelled 32.1 36 PDB header:hydrolase Chain: A: PDB Molecule:karilysin protease; PDBTitle: structure of karilysin catalytic mmp domain in complex with2 magnesium 81 d1hv5a_ not modelled 32.0 36 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 82 c2x7mA_ not modelled 31.3 18 PDB header:hydrolase Chain: A: PDB Molecule:archaemetzincin; PDBTitle: crystal structure of archaemetzincin (amza) from methanopyrus2 kandleri at 1.5 a resolution 83 d1cxva_ not modelled 30.2 19 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 84 d1i76a_ not modelled 29.7 36 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 85 d1hfca_ not modelled 28.9 45 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 86 d1mmqa_ not modelled 28.5 27 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 87 d1xuca1 not modelled 28.5 36 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 88 c2k9mA_ not modelled 28.2 22 PDB header:transcription Chain: A: PDB Molecule:rna polymerase sigma factor rpon; PDBTitle: structure of the core binding domain of sigma54 89 d1qiba_ not modelled 27.9 36 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 90 d1y93a1 not modelled 27.9 27 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 91 d1q3aa_ not modelled 27.5 36 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 92 d1hy7a_ not modelled 27.5 36 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 93 d2ovxa1 not modelled 27.4 27 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 94 d1cgla_ not modelled 27.3 45 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 95 d1lsha1 not modelled 25.9 13 Fold:alpha-alpha superhelix Superfamily:Lipovitellin-phosvitin complex, superhelical domain Family:Lipovitellin-phosvitin complex, superhelical domain 96 d1s5qb_ not modelled 25.7 11 Fold:PAH2 domain Superfamily:PAH2 domain Family:PAH2 domain 97 c2py8B_ not modelled 25.4 20 PDB header:chaperone Chain: B: PDB Molecule:hypothetical protein rbcx; PDBTitle: rbcx 98 c2jsdA_ not modelled 25.0 36 PDB header:hydrolase Chain: A: PDB Molecule:matrix metalloproteinase-20; PDBTitle: solution structure of mmp20 complexed with nngh 99 d1vh8a_ not modelled 24.8 10 Fold:Bacillus chorismate mutase-like Superfamily:IpsF-like Family:IpsF-like 100 d1x2ia1 not modelled 24.8 15 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Hef domain-like 101 d1hova_ not modelled 24.8 23 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 102 d1kfta_ not modelled 23.5 24 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Excinuclease UvrC C-terminal domain 103 c1kftA_ not modelled 23.5 24 PDB header:dna binding protein Chain: A: PDB Molecule:excinuclease abc subunit c; PDBTitle: solution structure of the c-terminal domain of uvrc from e-2 coli 104 d1st6a5 not modelled 23.3 14 Fold:Four-helical up-and-down bundle Superfamily:alpha-catenin/vinculin-like Family:alpha-catenin/vinculin 105 d2py8a1 not modelled 23.0 22 Fold:RbcX-like Superfamily:RbcX-like Family:RbcX-like 106 c2veeC_ not modelled 22.6 8 PDB header:transport protein Chain: C: PDB Molecule:protoglobin; PDBTitle: structure of protoglobin from methanosarcina acetivorans2 c2a 107 d1eaka2 not modelled 22.5 27 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 108 d2vv5a2 not modelled 21.9 11 Fold:Ferredoxin-like Superfamily:Mechanosensitive channel protein MscS (YggB), C-terminal domain Family:Mechanosensitive channel protein MscS (YggB), C-terminal domain 109 c2z0uB_ not modelled 21.7 10 PDB header:lipid binding protein Chain: B: PDB Molecule:ww domain-containing protein 1; PDBTitle: crystal structure of c2 domain of kibra protein 110 c3pkrA_ not modelled 21.7 12 PDB header:motor protein Chain: A: PDB Molecule:flagellar motor switch protein; PDBTitle: crystal structure of flig (residue 86-343) from h. pylori 111 d1fbla2 not modelled 21.4 45 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 112 d1j9ia_ not modelled 20.6 22 Fold:Putative DNA-binding domain Superfamily:Putative DNA-binding domain Family:Terminase gpNU1 subunit domain 113 d1c7ka_ not modelled 20.3 56 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Zinc protease 114 c2cltB_ not modelled 20.1 36 PDB header:hydrolase Chain: B: PDB Molecule:interstitial collagenase; PDBTitle: crystal structure of the active form (full-length) of human2 fibroblast collagenase.