Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	F	D	I	G	V	N	L	T	S	S	Q	F	A	K	D	R	D	D	V	V	A	C	A	F	D	A	G	V	N	G	L	L	I	T	G	T	N	L	R	E	S	Q	Q	A	Q	K	L	A	R	Q	Y	S	S	C	W	S	T	A	G
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	H	P	H	D	S	S	Q	W	Q	A	A	T	E	E	A	I	I	E	L	A	A	Q	P	E	V	V	A	I	G	E	C	G	L	D	F	N	R	N	F	S	T	P	E	E	Q	E	R	A	F	V	A	Q	L	R	I	A	A	D	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		N	M	P	V	F	M	H	C	R	D	A	H	E	R	F	M	T	L	L	E	P	W	L	D	K	L	P	G	A	V	L	H	C	F	T	G	T	R	E	E	M	Q	A	C	V	A	H	G	I	Y	I	G	I	T	G	W	V	C	D	E
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		R	R	G	L	E	L	R	E	L	L	P	L	I	P	A	E	K	L	L	I	E	T	D	A	P	Y	L	L	P	R	D	L	T	P	K	P	S	S	R	R	N	E	P	A	H	L	P	H	I	L	Q	R	I	A	H	W	R	G	E	D
Secondary structure
SS confidence
Disorder																																	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260
Sequence		A	A	W	L	A	A	T	T	D	A	N	V	K	T	L	F	G	I	A	F
Secondary structure
SS confidence
Disorder																		?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1xwy chain A domain 1 Region: 1 - 260 Aligned: 260 Modelled: 260 Confidence: 100.0% Identity: 100% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: TatD Mg-dependent DNase-like Phyre2 PDB 3rcm chain A Region: 1 - 258 Aligned: 258 Modelled: 258 Confidence: 100.0% Identity: 50% PDB header:hydrolase Chain: A: PDB Molecule:tatd family hydrolase; PDBTitle: crystal structure of efi target 500140:tatd family hydrolase from2 pseudomonas putida Phyre2 PDB 2gzx chain B Region: 1 - 257 Aligned: 252 Modelled: 252 Confidence: 100.0% Identity: 31% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative tatd related dnase; PDBTitle: crystal structure of the tatd deoxyribonuclease mw0446 from2 staphylococcus aureus. northeast structural genomics consortium3 target zr237. Phyre2 PDB 1j6o chain A Region: 1 - 259 Aligned: 254 Modelled: 254 Confidence: 100.0% Identity: 31% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: TatD Mg-dependent DNase-like Phyre2 PDB 3ipw chain A Region: 1 - 256 Aligned: 253 Modelled: 254 Confidence: 100.0% Identity: 33% PDB header:hydrolase Chain: A: PDB Molecule:hydrolase tatd family protein; PDBTitle: crystal structure of hydrolase tatd family protein from entamoeba2 histolytica Phyre2 PDB 2xio chain A Region: 1 - 257 Aligned: 254 Modelled: 257 Confidence: 100.0% Identity: 36% PDB header:hydrolase Chain: A: PDB Molecule:putative deoxyribonuclease tatdn1; PDBTitle: structure of putative deoxyribonuclease tatdn1 isoform a Phyre2 PDB 1zzm chain A domain 1 Region: 1 - 258 Aligned: 252 Modelled: 254 Confidence: 100.0% Identity: 25% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: TatD Mg-dependent DNase-like Phyre2 PDB 3e2v chain A Region: 1 - 257 Aligned: 256 Modelled: 256 Confidence: 100.0% Identity: 32% PDB header:hydrolase Chain: A: PDB Molecule:3'-5'-exonuclease; PDBTitle: crystal structure of an uncharacterized amidohydrolase from2 saccharomyces cerevisiae Phyre2 PDB 1yix chain A domain 1 Region: 1 - 258 Aligned: 251 Modelled: 258 Confidence: 100.0% Identity: 33% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: TatD Mg-dependent DNase-like Phyre2 PDB 2y1h chain A Region: 1 - 257 Aligned: 246 Modelled: 257 Confidence: 100.0% Identity: 26% PDB header:hydrolase Chain: A: PDB Molecule:putative deoxyribonuclease tatdn3; PDBTitle: crystal structure of the human tatd-domain protein 3 (tatdn3) Phyre2 PDB 3gg7 chain A Region: 1 - 257 Aligned: 239 Modelled: 247 Confidence: 100.0% Identity: 22% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized metalloprotein; PDBTitle: crystal structure of an uncharacterized metalloprotein from2 deinococcus radiodurans Phyre2 PDB 3irs chain B Region: 1 - 259 Aligned: 234 Modelled: 234 Confidence: 100.0% Identity: 14% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein bb4693; PDBTitle: crystal structure of uncharacterized tim-barrel protein bb4693 from2 bordetella bronchiseptica Phyre2 PDB 2wm1 chain A Region: 1 - 258 Aligned: 234 Modelled: 242 Confidence: 100.0% Identity: 19% PDB header:lyase Chain: A: PDB Molecule:2-amino-3-carboxymuconate-6-semialdehyde PDBTitle: the crystal structure of human alpha-amino-beta-2 carboxymuconate-epsilon-semialdehyde decarboxylase in3 complex with 1,3- dihydroxyacetonephosphate suggests a4 regulatory link between nad synthesis and glycolysis Phyre2 PDB 2f6k chain A domain 1 Region: 2 - 257 Aligned: 230 Modelled: 241 Confidence: 100.0% Identity: 17% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: PP1699/LP2961-like Phyre2 PDB 3guw chain B Region: 1 - 258 Aligned: 214 Modelled: 238 Confidence: 100.0% Identity: 18% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein af_1765; PDBTitle: crystal structure of the tatd-like protein (af1765) from2 archaeoglobus fulgidus, northeast structural genomics3 consortium target gr121 Phyre2 PDB 2gwg chain A domain 1 Region: 1 - 259 Aligned: 247 Modelled: 247 Confidence: 100.0% Identity: 13% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: PP1699/LP2961-like Phyre2 PDB 2ffi chain A domain 1 Region: 1 - 258 Aligned: 233 Modelled: 235 Confidence: 100.0% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: PP1699/LP2961-like Phyre2 PDB 3nur chain A Region: 1 - 258 Aligned: 232 Modelled: 239 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolase; PDBTitle: crystal structure of a putative amidohydrolase from staphylococcus2 aureus Phyre2 PDB 2dvt chain A domain 1 Region: 2 - 258 Aligned: 231 Modelled: 239 Confidence: 100.0% Identity: 16% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: PP1699/LP2961-like Phyre2 PDB 3cjp chain A Region: 1 - 258 Aligned: 220 Modelled: 241 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:predicted amidohydrolase, dihydroorotase family; PDBTitle: crystal structure of an uncharacterized amidohydrolase cac3332 from2 clostridium acetobutylicum Phyre2 1 d1xwya1 2 c3rcmA_ 3 c2gzxB_ 4 d1j6oa_ 5 c3ipwA_ 6 c2xioA_ 7 d1zzma1 8 c3e2vA_ 9 d1yixa1 10 c2y1hA_ 11 c3gg7A_ 12 c3irsB_ 13 c2wm1A_ 14 d2f6ka1 15 c3guwB_ 16 d2gwga1 17 d2ffia1 18 c3nurA_ 19 d2dvta1 20 c3cjpA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1xwya1 100.0 100 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:TatD Mg-dependent DNase-like 2 c3rcmA_ 100.0 50 PDB header:hydrolase Chain: A: PDB Molecule:tatd family hydrolase; PDBTitle: crystal structure of efi target 500140:tatd family hydrolase from2 pseudomonas putida 3 c2gzxB_ 100.0 31 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative tatd related dnase; PDBTitle: crystal structure of the tatd deoxyribonuclease mw0446 from2 staphylococcus aureus. northeast structural genomics consortium3 target zr237. 4 d1j6oa_ 100.0 31 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:TatD Mg-dependent DNase-like 5 c3ipwA_ 100.0 33 PDB header:hydrolase Chain: A: PDB Molecule:hydrolase tatd family protein; PDBTitle: crystal structure of hydrolase tatd family protein from entamoeba2 histolytica 6 c2xioA_ 100.0 36 PDB header:hydrolase Chain: A: PDB Molecule:putative deoxyribonuclease tatdn1; PDBTitle: structure of putative deoxyribonuclease tatdn1 isoform a 7 d1zzma1 100.0 25 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:TatD Mg-dependent DNase-like 8 c3e2vA_ 100.0 32 PDB header:hydrolase Chain: A: PDB Molecule:3'-5'-exonuclease; PDBTitle: crystal structure of an uncharacterized amidohydrolase from2 saccharomyces cerevisiae 9 d1yixa1 100.0 33 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:TatD Mg-dependent DNase-like 10 c2y1hA_ 100.0 26 PDB header:hydrolase Chain: A: PDB Molecule:putative deoxyribonuclease tatdn3; PDBTitle: crystal structure of the human tatd-domain protein 3 (tatdn3) 11 c3gg7A_ 100.0 22 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized metalloprotein; PDBTitle: crystal structure of an uncharacterized metalloprotein from2 deinococcus radiodurans 12 c3irsB_ 100.0 14 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein bb4693; PDBTitle: crystal structure of uncharacterized tim-barrel protein bb4693 from2 bordetella bronchiseptica 13 c2wm1A_ 100.0 19 PDB header:lyase Chain: A: PDB Molecule:2-amino-3-carboxymuconate-6-semialdehyde PDBTitle: the crystal structure of human alpha-amino-beta-2 carboxymuconate-epsilon-semialdehyde decarboxylase in3 complex with 1,3- dihydroxyacetonephosphate suggests a4 regulatory link between nad synthesis and glycolysis 14 d2f6ka1 100.0 17 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 15 c3guwB_ 100.0 18 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein af_1765; PDBTitle: crystal structure of the tatd-like protein (af1765) from2 archaeoglobus fulgidus, northeast structural genomics3 consortium target gr121 16 d2gwga1 100.0 13 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 17 d2ffia1 100.0 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 18 c3nurA_ 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolase; PDBTitle: crystal structure of a putative amidohydrolase from staphylococcus2 aureus 19 d2dvta1 100.0 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 20 c3cjpA_ 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:predicted amidohydrolase, dihydroorotase family; PDBTitle: crystal structure of an uncharacterized amidohydrolase cac3332 from2 clostridium acetobutylicum 21 c3ij6A_ not modelled 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized metal-dependent hydrolase; PDBTitle: crystal structure of an uncharacterized metal-dependent2 hydrolase from lactobacillus acidophilus 22 d2hbva1 not modelled 100.0 17 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 23 c2qahA_ not modelled 100.0 13 PDB header:hydrolase Chain: A: PDB Molecule:2-pyrone-4,6-dicarboxylic acid hydrolase; PDBTitle: crystal structure of the 2-pyrone-4,6-dicarboxylic acid2 hydrolase from sphingomonas paucimobilis 24 c3f4cA_ not modelled 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:organophosphorus hydrolase; PDBTitle: crystal structure of organophosphorus hydrolase from geobacillus2 stearothermophilus strain 10, with glycerol bound 25 d1bf6a_ not modelled 99.9 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Phosphotriesterase-like 26 c2vc7A_ not modelled 99.9 13 PDB header:hydrolase Chain: A: PDB Molecule:aryldialkylphosphatase; PDBTitle: structural basis for natural lactonase and promiscuous2 phosphotriesterase activities 27 d1i0da_ not modelled 99.9 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Phosphotriesterase-like 28 c3pnzD_ not modelled 99.9 10 PDB header:hydrolase Chain: D: PDB Molecule:phosphotriesterase family protein; PDBTitle: crystal structure of the lactonase lmo2620 from listeria monocytogenes 29 d2d2ja1 not modelled 99.9 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Phosphotriesterase-like 30 c2zc1A_ not modelled 99.9 16 PDB header:hydrolase Chain: A: PDB Molecule:phosphotriesterase; PDBTitle: organophosphorus hydrolase from deinococcus radiodurans 31 c1pscA_ not modelled 99.9 16 PDB header:hydrolase Chain: A: PDB Molecule:phosphotriesterase; PDBTitle: phosphotriesterase from pseudomonas diminuta 32 c3k2gA_ not modelled 99.9 17 PDB header:resiniferatoxin binding protein Chain: A: PDB Molecule:resiniferatoxin-binding, phosphotriesterase- PDBTitle: crystal structure of a resiniferatoxin-binding protein from2 rhodobacter sphaeroides 33 c3rhgA_ not modelled 99.8 14 PDB header:hydrolase Chain: A: PDB Molecule:putative phophotriesterase; PDBTitle: crystal structure of amidohydrolase pmi1525 (target efi-500319) from2 proteus mirabilis hi4320 34 c2qpxA_ not modelled 99.7 12 PDB header:hydrolase Chain: A: PDB Molecule:predicted metal-dependent hydrolase of the tim-barrel fold; PDBTitle: crystal structure of putative metal-dependent hydrolase (yp_805737.1)2 from lactobacillus casei atcc 334 at 1.40 a resolution 35 d1xrta2 not modelled 99.7 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 36 d2eg6a1 not modelled 99.7 18 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Dihydroorotase 37 c3jzeC_ not modelled 99.7 19 PDB header:hydrolase Chain: C: PDB Molecule:dihydroorotase; PDBTitle: 1.8 angstrom resolution crystal structure of dihydroorotase (pyrc)2 from salmonella enterica subsp. enterica serovar typhimurium str. lt2 38 c3pnuA_ not modelled 99.7 15 PDB header:hydrolase Chain: A: PDB Molecule:dihydroorotase; PDBTitle: 2.4 angstrom crystal structure of dihydroorotase (pyrc) from2 campylobacter jejuni. 39 d1k1da2 not modelled 99.6 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 40 d1nfga2 not modelled 99.6 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 41 d1gkra2 not modelled 99.6 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 42 c3msrA_ not modelled 99.5 12 PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolases; PDBTitle: the crystal structure of an amidohydrolase from mycoplasma synoviae 43 d1ynya2 not modelled 99.5 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 44 d1kcxa2 not modelled 99.4 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 45 d2ftwa2 not modelled 99.4 13 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 46 d2fvka2 not modelled 99.3 11 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 47 d1gkpa2 not modelled 99.3 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 48 d2uz9a2 not modelled 99.2 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 49 d2imra2 not modelled 99.2 11 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:DR0824-like 50 d1onwa2 not modelled 99.2 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Isoaspartyl dipeptidase, catalytic domain 51 c3nqbB_ not modelled 99.2 14 PDB header:hydrolase Chain: B: PDB Molecule:adenine deaminase 2; PDBTitle: crystal structure of adenine deaminase from agrobacterium tumefaciens2 (str. c 58) 52 d2paja2 not modelled 99.2 9 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 53 d2icsa2 not modelled 99.2 13 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Adenine deaminase-like 54 c1xrfA_ not modelled 99.2 14 PDB header:hydrolase Chain: A: PDB Molecule:dihydroorotase; PDBTitle: the crystal structure of a novel, latent dihydroorotase from aquifex2 aeolicus at 1.7 a resolution 55 d1p1ma2 not modelled 99.2 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 56 c3e0lB_ not modelled 99.2 11 PDB header:hydrolase Chain: B: PDB Molecule:guanine deaminase; PDBTitle: computationally designed ammelide deaminase 57 d2i9ua2 not modelled 99.1 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 58 d3be7a2 not modelled 99.1 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Zn-dependent arginine carboxypeptidase-like 59 c2vunC_ not modelled 99.1 15 PDB header:hydrolase Chain: C: PDB Molecule:enamidase; PDBTitle: the crystal structure of enamidase at 1.9 a resolution - a2 new member of the amidohydrolase superfamily 60 d2r8ca2 not modelled 99.0 13 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Zn-dependent arginine carboxypeptidase-like 61 d2p9ba2 not modelled 99.0 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Imidazolonepropionase-like 62 d2qs8a2 not modelled 99.0 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Zn-dependent arginine carboxypeptidase-like 63 c1p1mA_ not modelled 98.9 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein tm0936; PDBTitle: structure of thermotoga maritima amidohydrolase tm09362 bound to ni and methionine 64 c2pajA_ not modelled 98.9 10 PDB header:hydrolase Chain: A: PDB Molecule:putative cytosine/guanine deaminase; PDBTitle: crystal structure of an amidohydrolase from an environmental sample of2 sargasso sea 65 d2bb0a2 not modelled 98.9 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Imidazolonepropionase-like 66 d1un7a2 not modelled 98.9 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain 67 d1itua_ not modelled 98.8 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Renal dipeptidase 68 c2i5gB_ not modelled 98.8 13 PDB header:hydrolase Chain: B: PDB Molecule:amidohydrolase; PDBTitle: crystal strcuture of amidohydrolase from pseudomonas2 aeruginosa 69 c3fdgA_ not modelled 98.8 14 PDB header:hydrolase Chain: A: PDB Molecule:dipeptidase ac. metallo peptidase. merops family m19; PDBTitle: the crystal structure of the dipeptidase ac, metallo peptidase. merops2 family m19 70 c2q09A_ not modelled 98.8 16 PDB header:hydrolase Chain: A: PDB Molecule:imidazolonepropionase; PDBTitle: crystal structure of imidazolonepropionase from environmental sample2 with bound inhibitor 3-(2,5-dioxo-imidazolidin-4-yl)-propionic acid 71 c2ragB_ not modelled 98.8 14 PDB header:hydrolase Chain: B: PDB Molecule:dipeptidase; PDBTitle: crystal structure of aminohydrolase from caulobacter crescentus 72 d1yrra2 not modelled 98.8 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain 73 c3b40A_ not modelled 98.8 12 PDB header:hydrolase Chain: A: PDB Molecule:probable dipeptidase; PDBTitle: crystal structure of the probable dipeptidase pvdm from2 pseudomonas aeruginosa 74 c2imrA_ not modelled 98.8 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein dr_0824; PDBTitle: crystal structure of amidohydrolase dr_0824 from2 deinococcus radiodurans 75 d2ooda2 not modelled 98.8 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 76 c3ou8B_ not modelled 98.8 12 PDB header:hydrolase Chain: B: PDB Molecule:adenosine deaminase; PDBTitle: the crystal structure of adenosine deaminase from pseudomonas2 aeruginosa 77 c3lnpA_ not modelled 98.7 14 PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolase family protein olei01672_1_465; PDBTitle: crystal structure of amidohydrolase family protein2 olei01672_1_465 from oleispira antarctica 78 c3hpaB_ not modelled 98.7 8 PDB header:hydrolase Chain: B: PDB Molecule:amidohydrolase; PDBTitle: crystal structure of an amidohydrolase gi:44264246 from an2 evironmental sample of sargasso sea 79 c2i9uA_ not modelled 98.7 11 PDB header:hydrolase Chain: A: PDB Molecule:cytosine/guanine deaminase related protein; PDBTitle: crystal structure of guanine deaminase from c. acetobutylicum with2 bound guanine in the active site 80 c1k1dF_ not modelled 98.7 9 PDB header:hydrolase Chain: F: PDB Molecule:d-hydantoinase; PDBTitle: crystal structure of d-hydantoinase 81 c3dc8B_ not modelled 98.7 12 PDB header:hydrolase Chain: B: PDB Molecule:dihydropyrimidinase; PDBTitle: crystal structure of dihydropyrimidinase from sinorhizobium meliloti 82 c3v7pA_ not modelled 98.7 13 PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolase family protein; PDBTitle: crystal structure of amidohydrolase nis_0429 (target efi-500396) from2 nitratiruptor sp. sb155-2 83 c1gkpD_ not modelled 98.7 12 PDB header:hydrolase Chain: D: PDB Molecule:hydantoinase; PDBTitle: d-hydantoinase (dihydropyrimidinase) from thermus sp. in2 space group c2221 84 d2q09a2 not modelled 98.7 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Imidazolonepropionase-like 85 c2ftwA_ not modelled 98.7 13 PDB header:hydrolase Chain: A: PDB Molecule:dihydropyrimidine amidohydrolase; PDBTitle: crystal structure of dihydropyrimidinase from dictyostelium discoideum 86 d1ra0a2 not modelled 98.7 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Cytosine deaminase catalytic domain 87 c2ogjB_ not modelled 98.6 14 PDB header:hydrolase Chain: B: PDB Molecule:dihydroorotase; PDBTitle: crystal structure of a dihydroorotase 88 c2bb0A_ not modelled 98.6 14 PDB header:hydrolase Chain: A: PDB Molecule:imidazolonepropionase; PDBTitle: structure of imidazolonepropionase from bacillus subtilis 89 c2vr2A_ not modelled 98.6 13 PDB header:hydrolase Chain: A: PDB Molecule:dihydropyrimidinase; PDBTitle: human dihydropyrimidinase 90 c3ou8A_ not modelled 98.6 13 PDB header:hydrolase Chain: A: PDB Molecule:adenosine deaminase; PDBTitle: the crystal structure of adenosine deaminase from pseudomonas2 aeruginosa 91 c2gokA_ not modelled 98.6 13 PDB header:hydrolase Chain: A: PDB Molecule:imidazolonepropionase; PDBTitle: crystal structure of the imidazolonepropionase from agrobacterium2 tumefaciens at 1.87 a resolution 92 c3d6nA_ not modelled 98.6 13 PDB header:hydrolase/transferase Chain: A: PDB Molecule:dihydroorotase; PDBTitle: crystal structure of aquifex dihydroorotase activated by aspartate2 transcarbamoylase 93 d1j5sa_ not modelled 98.6 18 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Uronate isomerase-like 94 c1r9yA_ not modelled 98.6 14 PDB header:hydrolase Chain: A: PDB Molecule:cytosine deaminase; PDBTitle: bacterial cytosine deaminase d314a mutant. 95 c3hm7A_ not modelled 98.6 15 PDB header:hydrolase Chain: A: PDB Molecule:allantoinase; PDBTitle: crystal structure of allantoinase from bacillus halodurans c-125 96 c3lsbA_ not modelled 98.6 15 PDB header:hydrolase Chain: A: PDB Molecule:triazine hydrolase; PDBTitle: crystal structure of the mutant e241q of atrazine chlorohydrolase trzn2 from arthrobacter aurescens tc1 complexed with zinc and ametrin 97 d2puza2 not modelled 98.6 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Imidazolonepropionase-like 98 c3ighX_ not modelled 98.5 13 PDB header:hydrolase Chain: X: PDB Molecule:uncharacterized metal-dependent hydrolase; PDBTitle: crystal structure of an uncharacterized metal-dependent2 hydrolase from pyrococcus horikoshii ot3 99 c1nfgA_ not modelled 98.5 13 PDB header:hydrolase Chain: A: PDB Molecule:d-hydantoinase; PDBTitle: structure of d-hydantoinase 100 c2aqoB_ not modelled 98.5 14 PDB header:hydrolase Chain: B: PDB Molecule:isoaspartyl dipeptidase; PDBTitle: crystal structure of e. coli isoaspartyl dipeptidase mutant e77q 101 c3gnhA_ not modelled 98.5 13 PDB header:hydrolase Chain: A: PDB Molecule:l-lysine, l-arginine carboxypeptidase cc2672; PDBTitle: crystal structure of l-lysine, l-arginine carboxypeptidase cc2672 from2 caulobacter crescentus cb15 complexed with n-methyl phosphonate3 derivative of l-arginine. 102 c1gkrA_ not modelled 98.5 14 PDB header:hydrolase Chain: A: PDB Molecule:non-atp dependent l-selective hydantoinase; PDBTitle: l-hydantoinase (dihydropyrimidinase) from arthrobacter2 aurescens 103 c2oodA_ not modelled 98.4 13 PDB header:hydrolase Chain: A: PDB Molecule:blr3880 protein; PDBTitle: crystal structure of guanine deaminase from bradyrhizobium japonicum 104 d4ubpc2 not modelled 98.4 18 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:alpha-subunit of urease, catalytic domain 105 d1o12a2 not modelled 98.4 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain 106 c2qt3A_ not modelled 98.3 11 PDB header:hydrolase Chain: A: PDB Molecule:n-isopropylammelide isopropyl amidohydrolase; PDBTitle: crystal structure of n-isopropylammelide isopropylaminohydrolase atzc2 from pseudomonas sp. strain adp complexed with zn 107 c2q01A_ not modelled 98.3 14 PDB header:isomerase Chain: A: PDB Molecule:uronate isomerase; PDBTitle: crystal structure of glucuronate isomerase from caulobacter crescentus 108 c2gseC_ not modelled 98.3 13 PDB header:hydrolase Chain: C: PDB Molecule:dihydropyrimidinase-related protein 2; PDBTitle: crystal structure of human dihydropyrimidinease-like 2 109 c3lu2B_ not modelled 98.2 12 PDB header:hydrolase Chain: B: PDB Molecule:lmo2462 protein; PDBTitle: structure of lmo2462, a listeria monocytogenes amidohydrolase family2 putative dipeptidase 110 d1m7ja3 not modelled 98.2 19 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:D-aminoacylase, catalytic domain 111 c3e74D_ not modelled 98.2 10 PDB header:hydrolase Chain: D: PDB Molecule:allantoinase; PDBTitle: crystal structure of e. coli allantoinase with iron ions at2 the metal center 112 c3mpgB_ not modelled 98.2 11 PDB header:hydrolase Chain: B: PDB Molecule:dihydroorotase; PDBTitle: dihydroorotase from bacillus anthracis 113 c3etkA_ not modelled 98.2 14 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized metal-dependent hydrolase; PDBTitle: crystal structure of an uncharacterized metal-dependent2 hydrolase from pyrococcus furiosus 114 c3rysA_ not modelled 98.2 15 PDB header:hydrolase Chain: A: PDB Molecule:adenosine deaminase 1; PDBTitle: the crystal structure of adenine deaminase (aaur1117) from2 arthrobacter aurescens 115 c2fvmA_ not modelled 98.1 14 PDB header:hydrolase Chain: A: PDB Molecule:dihydropyrimidinase; PDBTitle: crystal structure of dihydropyrimidinase from saccharomyces kluyveri2 in complex with the reaction product n-carbamyl-beta-alanine 116 c3griB_ not modelled 98.1 9 PDB header:hydrolase Chain: B: PDB Molecule:dihydroorotase; PDBTitle: the crystal structure of a dihydroorotase from staphylococcus aureus 117 c3itcA_ not modelled 98.1 22 PDB header:hydrolase Chain: A: PDB Molecule:renal dipeptidase; PDBTitle: crystal structure of sco3058 with bound citrate and glycerol 118 c2icsA_ not modelled 98.1 13 PDB header:hydrolase Chain: A: PDB Molecule:adenine deaminase; PDBTitle: crystal structure of an adenine deaminase 119 c3mduA_ not modelled 97.9 16 PDB header:hydrolase Chain: A: PDB Molecule:n-formimino-l-glutamate iminohydrolase; PDBTitle: the structure of n-formimino-l-glutamate iminohydrolase from2 pseudomonas aeruginosa complexed with n-guanidino-l-glutamate 120 d1e9yb2 not modelled 97.9 27 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:alpha-subunit of urease, catalytic domain

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0