Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0A9Q7
DateThu Jan 5 11:11:00 GMT 2012
Unique Job ID7bdde0d10c8225b4

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3k9dD_
Top template information
PDB header:oxidoreductase
Chain: D: PDB Molecule:aldehyde dehydrogenase;
PDBTitle: crystal structure of probable aldehyde dehydrogenase from listeria2 monocytogenes egd-e
Confidence and coverage
Confidence:100.0% Coverage: 49%
438 residues ( 49% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
830 residues ( 93%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MAVTNVAELNALVERVKKAQREYASFTQEQVDKIFRAAALAAADARIPLAKMAVAESGMG
Secondary structure 
SS confidence 
Disorder  ?????
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  IVEDKVIKNHFASEYIYNAYKDEKTCGVLSEDDTFGTITIAEPIGIICGIVPTTNPTSTA
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  IFKSLISLKTRNAIIFSPHPRAKDATNKAADIVLQAAIAAGAPKDLIGWIDQPSVELSNA
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  LMHHPDINLILATGGPGMVKAAYSSGKPAIGVGAGNTPVVIDETADIKRAVASVLMSKTF
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  DNGVICASEQSVVVVDSVYDAVRERFATHGGYLLQGKELKAVQDVILKNGALNAAIVGQP
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  AYKIAELAGFSVPENTKILIGEVTVVDESEPFAHEKLSPTLAMYRAKDFEDAVEKAEKLV
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  AMGGIGHTSCLYTDQDNQPARVSYFGQKMKTARILINTPASQGGIGDLYNFKLAPSLTLG
Secondary structure 
SS confidence 
Disorder 
??
Disorder confidence 
 
   .........430.........440.........450.........460.........470.........480
Sequence  CGSWGGNSISENVGPKHLINKKTVAKRAENMLWHKLPKSIYFRRGSLPIALDEVITDGHK
Secondary structure 
SS confidence 
Disorder 
??
?
????
??
???
??
Disorder confidence 
 
   .........490.........500.........510.........520.........530.........540
Sequence  RALIVTDRFLFNNGYADQITSVLKAAGVETEVFFEVEADPTLSIVRKGAELANSFKPDVI
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........550.........560.........570.........580.........590.........600
Sequence  IALGGGSPMDAAKIMWVMYEHPETHFEELALRFMDIRKRIYKFPKMGVKAKMIAVTTTSG
Secondary structure 
SS confidence 
Disorder 
???????????
Disorder confidence 
 
   .........610.........620.........630.........640.........650.........660
Sequence  TGSEVTPFAVVTDDATGQKYPLADYALTPDMAIVDANLVMDMPKSLCAFGGLDAVTHAME
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........670.........680.........690.........700.........710.........720
Sequence  AYVSVLASEFSDGQALQALKLLKEYLPASYHEGSKNPVARERVHSAATIAGIAFANAFLG
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........730.........740.........750.........760.........770.........780
Sequence  VCHSMAHKLGSQFHIPHGLANALLICNVIRYNANDNPTKQTAFSQYDRPQARRRYAEIAD
Secondary structure 
SS confidence 
Disorder 
?
?
?
???
Disorder confidence 
 
   .........790.........800.........810.........820.........830.........840
Sequence  HLGLSAPGDRTAAKIEKLLAWLETLKAELGIPKSIREAGVQEADFLANVDKLSEDAFDDQ
Secondary structure 
SS confidence 
Disorder 
???
?
Disorder confidence 
 
   .........850.........860.........870.........880.........890.
Sequence  CTGANPRYPLISELKQILLDTYYGRDYVEGETAAKKEAAPAKAEKKAKKSA
Secondary structure 
SS confidence 
Disorder 
????????????????????????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3k9d chain D

3D model

Region: 5 - 447
Aligned: 438
Modelled: 443
Confidence: 100.0%
Identity: 46%
PDB header:oxidoreductase
Chain: D: PDB Molecule:aldehyde dehydrogenase;
PDBTitle: crystal structure of probable aldehyde dehydrogenase from listeria2 monocytogenes egd-e

Phyre2

PDB 3my7 chain A

3D model

Region: 3 - 447
Aligned: 408
Modelled: 413
Confidence: 100.0%
Identity: 75%
PDB header:oxidoreductase
Chain: A: PDB Molecule:alcohol dehydrogenase/acetaldehyde dehydrogenase;
PDBTitle: the crystal structure of the acdh domain of an alcohol dehydrogenase2 from vibrio parahaemolyticus to 2.25a

Phyre2

PDB 3bfj chain K

3D model

Region: 451 - 862
Aligned: 381
Modelled: 397
Confidence: 100.0%
Identity: 34%
PDB header:oxidoreductase
Chain: K: PDB Molecule:1,3-propanediol oxidoreductase;
PDBTitle: crystal structure analysis of 1,3-propanediol oxidoreductase

Phyre2

PDB 3ox4 chain D

3D model

Region: 454 - 862
Aligned: 378
Modelled: 394
Confidence: 100.0%
Identity: 33%
PDB header:oxidoreductase
Chain: D: PDB Molecule:alcohol dehydrogenase 2;
PDBTitle: structures of iron-dependent alcohol dehydrogenase 2 from zymomonas2 mobilis zm4 complexed with nad cofactor

Phyre2

PDB 1rrm chain A

3D model

Region: 452 - 864
Aligned: 382
Modelled: 386
Confidence: 100.0%
Identity: 32%
Fold: Dehydroquinate synthase-like
Superfamily: Dehydroquinate synthase-like
Family: Iron-containing alcohol dehydrogenase

Phyre2

PDB 1vlj chain A

3D model

Region: 450 - 861
Aligned: 379
Modelled: 397
Confidence: 100.0%
Identity: 25%
Fold: Dehydroquinate synthase-like
Superfamily: Dehydroquinate synthase-like
Family: Iron-containing alcohol dehydrogenase

Phyre2

PDB 1oj7 chain A

3D model

Region: 448 - 861
Aligned: 382
Modelled: 399
Confidence: 100.0%
Identity: 22%
Fold: Dehydroquinate synthase-like
Superfamily: Dehydroquinate synthase-like
Family: Iron-containing alcohol dehydrogenase

Phyre2

PDB 3haz chain A

3D model

Region: 1 - 444
Aligned: 411
Modelled: 440
Confidence: 100.0%
Identity: 18%
PDB header:oxidoreductase
Chain: A: PDB Molecule:proline dehydrogenase;
PDBTitle: crystal structure of bifunctional proline utilization a2 (puta) protein

Phyre2

PDB 1uzb chain A

3D model

Region: 1 - 447
Aligned: 418
Modelled: 447
Confidence: 100.0%
Identity: 23%
Fold: ALDH-like
Superfamily: ALDH-like
Family: ALDH-like

Phyre2

PDB 2jg7 chain G

3D model

Region: 1 - 448
Aligned: 423
Modelled: 440
Confidence: 100.0%
Identity: 19%
PDB header:oxidoreductase
Chain: G: PDB Molecule:antiquitin;
PDBTitle: crystal structure of seabream antiquitin and elucidation of2 its substrate specificity

Phyre2

PDB 3qan chain B

3D model

Region: 1 - 447
Aligned: 418
Modelled: 447
Confidence: 100.0%
Identity: 20%
PDB header:oxidoreductase
Chain: B: PDB Molecule:1-pyrroline-5-carboxylate dehydrogenase 1;
PDBTitle: crystal structure of 1-pyrroline-5-carboxylate dehydrogenase from2 bacillus halodurans

Phyre2

PDB 2d4e chain B

3D model

Region: 1 - 454
Aligned: 433
Modelled: 454
Confidence: 100.0%
Identity: 18%
PDB header:oxidoreductase
Chain: B: PDB Molecule:5-carboxymethyl-2-hydroxymuconate semialdehyde
PDBTitle: crystal structure of the hpcc from thermus thermophilus hb8

Phyre2

PDB 3ed6 chain B

3D model

Region: 1 - 455
Aligned: 429
Modelled: 455
Confidence: 100.0%
Identity: 19%
PDB header:oxidoreductase
Chain: B: PDB Molecule:betaine aldehyde dehydrogenase;
PDBTitle: 1.7 angstrom resolution crystal structure of betaine aldehyde2 dehydrogenase (betb) from staphylococcus aureus

Phyre2

PDB 1a4s chain A

3D model

Region: 1 - 449
Aligned: 424
Modelled: 436
Confidence: 100.0%
Identity: 20%
Fold: ALDH-like
Superfamily: ALDH-like
Family: ALDH-like

Phyre2

PDB 3iwk chain B

3D model

Region: 1 - 459
Aligned: 432
Modelled: 459
Confidence: 100.0%
Identity: 20%
PDB header:oxidoreductase
Chain: B: PDB Molecule:aminoaldehyde dehydrogenase;
PDBTitle: crystal structure of aminoaldehyde dehydrogenase 1 from2 pisum sativum (psamadh1)

Phyre2

PDB 3prl chain D

3D model

Region: 1 - 461
Aligned: 422
Modelled: 442
Confidence: 100.0%
Identity: 19%
PDB header:oxidoreductase
Chain: D: PDB Molecule:nadp-dependent glyceraldehyde-3-phosphate dehydrogenase;
PDBTitle: crystal structure of nadp-dependent glyceraldehyde-3-phosphate2 dehydrogenase from bacillus halodurans c-125

Phyre2

PDB 2w8q chain A

3D model

Region: 1 - 444
Aligned: 414
Modelled: 440
Confidence: 100.0%
Identity: 21%
PDB header:oxidoreductase
Chain: A: PDB Molecule:succinate-semialdehyde dehydrogenase,
PDBTitle: the crystal structure of human ssadh in complex with ssa.

Phyre2

PDB 3rf7 chain A

3D model

Region: 454 - 860
Aligned: 345
Modelled: 370
Confidence: 100.0%
Identity: 19%
PDB header:oxidoreductase
Chain: A: PDB Molecule:iron-containing alcohol dehydrogenase;
PDBTitle: crystal structure of an iron-containing alcohol dehydrogenase2 (sden_2133) from shewanella denitrificans os-217 at 2.12 a resolution

Phyre2

PDB 1o2d chain A

3D model

Region: 451 - 861
Aligned: 356
Modelled: 380
Confidence: 100.0%
Identity: 26%
Fold: Dehydroquinate synthase-like
Superfamily: Dehydroquinate synthase-like
Family: Iron-containing alcohol dehydrogenase

Phyre2

PDB 1bxs chain A

3D model

Region: 1 - 449
Aligned: 419
Modelled: 449
Confidence: 100.0%
Identity: 17%
Fold: ALDH-like
Superfamily: ALDH-like
Family: ALDH-like

Phyre2

PDB 3hl0 chain B

3D model

Region: 448 - 866
Aligned: 349
Modelled: 338
Confidence: 100.0%
Identity: 27%
PDB header:oxidoreductase
Chain: B: PDB Molecule:maleylacetate reductase;
PDBTitle: crystal structure of maleylacetate reductase from agrobacterium2 tumefaciens

Phyre2
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c3k9dD_
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c3my7A_
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c3bfjK_
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c3ox4D_
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d1rrma_
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d1vlja_
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d1oj7a_
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c3hazA_
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d1uzba_
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c2jg7G_
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c3qanB_
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d1a4sa_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3k9dD_
100.0 46 PDB header:oxidoreductase
Chain: D: PDB Molecule:aldehyde dehydrogenase;
PDBTitle: crystal structure of probable aldehyde dehydrogenase from listeria2 monocytogenes egd-e
2c3my7A_
100.0 75 PDB header:oxidoreductase
Chain: A: PDB Molecule:alcohol dehydrogenase/acetaldehyde dehydrogenase;
PDBTitle: the crystal structure of the acdh domain of an alcohol dehydrogenase2 from vibrio parahaemolyticus to 2.25a
3c3bfjK_
100.0 34 PDB header:oxidoreductase
Chain: K: PDB Molecule:1,3-propanediol oxidoreductase;
PDBTitle: crystal structure analysis of 1,3-propanediol oxidoreductase
4c3ox4D_
100.0 33 PDB header:oxidoreductase
Chain: D: PDB Molecule:alcohol dehydrogenase 2;
PDBTitle: structures of iron-dependent alcohol dehydrogenase 2 from zymomonas2 mobilis zm4 complexed with nad cofactor
5d1rrma_
100.0 32 Fold:Dehydroquinate synthase-like
Superfamily:Dehydroquinate synthase-like
Family:Iron-containing alcohol dehydrogenase
6d1vlja_
100.0 25 Fold:Dehydroquinate synthase-like
Superfamily:Dehydroquinate synthase-like
Family:Iron-containing alcohol dehydrogenase
7d1oj7a_
100.0 22 Fold:Dehydroquinate synthase-like
Superfamily:Dehydroquinate synthase-like
Family:Iron-containing alcohol dehydrogenase
8c3hazA_
100.0 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:proline dehydrogenase;
PDBTitle: crystal structure of bifunctional proline utilization a2 (puta) protein
9d1uzba_
100.0 23 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
10c2jg7G_
100.0 19 PDB header:oxidoreductase
Chain: G: PDB Molecule:antiquitin;
PDBTitle: crystal structure of seabream antiquitin and elucidation of2 its substrate specificity
11c3qanB_
100.0 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:1-pyrroline-5-carboxylate dehydrogenase 1;
PDBTitle: crystal structure of 1-pyrroline-5-carboxylate dehydrogenase from2 bacillus halodurans
12c2d4eB_
100.0 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:5-carboxymethyl-2-hydroxymuconate semialdehyde
PDBTitle: crystal structure of the hpcc from thermus thermophilus hb8
13c3ed6B_
100.0 19 PDB header:oxidoreductase
Chain: B: PDB Molecule:betaine aldehyde dehydrogenase;
PDBTitle: 1.7 angstrom resolution crystal structure of betaine aldehyde2 dehydrogenase (betb) from staphylococcus aureus
14d1a4sa_
100.0 20 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
15c3iwkB_
100.0 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:aminoaldehyde dehydrogenase;
PDBTitle: crystal structure of aminoaldehyde dehydrogenase 1 from2 pisum sativum (psamadh1)
16c3prlD_
100.0 19 PDB header:oxidoreductase
Chain: D: PDB Molecule:nadp-dependent glyceraldehyde-3-phosphate dehydrogenase;
PDBTitle: crystal structure of nadp-dependent glyceraldehyde-3-phosphate2 dehydrogenase from bacillus halodurans c-125
17c2w8qA_
100.0 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:succinate-semialdehyde dehydrogenase,
PDBTitle: the crystal structure of human ssadh in complex with ssa.
18c3rf7A_
100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:iron-containing alcohol dehydrogenase;
PDBTitle: crystal structure of an iron-containing alcohol dehydrogenase2 (sden_2133) from shewanella denitrificans os-217 at 2.12 a resolution
19d1o2da_
100.0 26 Fold:Dehydroquinate synthase-like
Superfamily:Dehydroquinate synthase-like
Family:Iron-containing alcohol dehydrogenase
20d1bxsa_
100.0 17 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
21d1o04a_
not modelled 100.0 20 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
22d1o9ja_
not modelled 100.0 17 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
23d1ad3a_
not modelled 100.0 14 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
24c3ek1C_
not modelled 100.0 20 PDB header:oxidoreductase
Chain: C: PDB Molecule:aldehyde dehydrogenase;
PDBTitle: crystal structure of aldehyde dehydrogenase from brucella2 melitensis biovar abortus 2308
25c2ve5H_
not modelled 100.0 23 PDB header:oxidoreductase
Chain: H: PDB Molecule:betaine aldehyde dehydrogenase;
PDBTitle: crystallographic structure of betaine aldehyde2 dehydrogenase from pseudomonas aeruginosa
26c3ifgH_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: H: PDB Molecule:succinate-semialdehyde dehydrogenase (nadp+);
PDBTitle: crystal structure of succinate-semialdehyde dehydrogenase from2 burkholderia pseudomallei, part 1 of 2
27c3hl0B_
100.0 27 PDB header:oxidoreductase
Chain: B: PDB Molecule:maleylacetate reductase;
PDBTitle: crystal structure of maleylacetate reductase from agrobacterium2 tumefaciens
28d1euha_
not modelled 100.0 21 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
29d1wnda_
not modelled 100.0 16 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
30d1ez0a_
not modelled 100.0 16 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
31c2o2qA_
not modelled 100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:formyltetrahydrofolate dehydrogenase;
PDBTitle: crystal structure of the c-terminal domain of rat2 10'formyltetrahydrofolate dehydrogenase in complex with nadp
32c1t90B_
not modelled 100.0 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:probable methylmalonate-semialdehyde
PDBTitle: crystal structure of methylmalonate semialdehyde2 dehydrogenase from bacillus subtilis
33c3iv7B_
not modelled 100.0 23 PDB header:oxidoreductase
Chain: B: PDB Molecule:alcohol dehydrogenase iv;
PDBTitle: crystal structure of iron-containing alcohol dehydrogenase2 (np_602249.1) from corynebacterium glutamicum atcc 13032 kitasato at3 2.07 a resolution
34c3rosA_
not modelled 100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:nad-dependent aldehyde dehydrogenase;
PDBTitle: crystal structure of nad-dependent aldehyde dehydrogenase from2 lactobacillus acidophilus
35d1ag8a_
not modelled 100.0 19 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
36d1ky8a_
not modelled 100.0 18 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
37c3pqaA_
not modelled 100.0 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:lactaldehyde dehydrogenase;
PDBTitle: crystal structure of glyceraldehyde-3-phosphate dehydrogenase gapn2 from methanocaldococcus jannaschii dsm 2661
38c3r31A_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:betaine aldehyde dehydrogenase;
PDBTitle: crystal structure of betaine aldehyde dehydrogenase from agrobacterium2 tumefaciens
39c3rh9A_
not modelled 100.0 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:succinate-semialdehyde dehydrogenase (nad(p)(+));
PDBTitle: the crystal structure of oxidoreductase from marinobacter aquaeolei
40c3i44A_
not modelled 100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:aldehyde dehydrogenase;
PDBTitle: crystal structure of aldehyde dehydrogenase from bartonella2 henselae at 2.0a resolution
41c3jz4C_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: C: PDB Molecule:succinate-semialdehyde dehydrogenase [nadp+];
PDBTitle: crystal structure of e. coli nadp dependent enzyme
42c3b4wA_
not modelled 100.0 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:aldehyde dehydrogenase;
PDBTitle: crystal structure of mycobacterium tuberculosis aldehyde dehydrogenase2 complexed with nad+
43d1bi9a_
not modelled 100.0 20 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
44c2hg2A_
not modelled 100.0 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:aldehyde dehydrogenase a;
PDBTitle: structure of lactaldehyde dehydrogenase
45c3k2wD_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: D: PDB Molecule:betaine-aldehyde dehydrogenase;
PDBTitle: crystal structure of betaine-aldehyde dehydrogenase from2 pseudoalteromonas atlantica t6c
46c3v4cB_
not modelled 100.0 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:aldehyde dehydrogenase (nadp+);
PDBTitle: crystal structure of a semialdehyde dehydrogenase from sinorhizobium2 meliloti 1021
47c3efvC_
not modelled 100.0 19 PDB header:oxidoreductase
Chain: C: PDB Molecule:putative succinate-semialdehyde dehydrogenase;
PDBTitle: crystal structure of a putative succinate-semialdehyde dehydrogenase2 from salmonella typhimurium lt2 with bound nad
48c3ju8B_
not modelled 100.0 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:succinylglutamic semialdehyde dehydrogenase;
PDBTitle: crystal structure of succinylglutamic semialdehyde dehydrogenase from2 pseudomonas aeruginosa.
49d1o20a_
not modelled 100.0 18 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
50c3jzdA_
not modelled 100.0 26 PDB header:oxidoreductase
Chain: A: PDB Molecule:iron-containing alcohol dehydrogenase;
PDBTitle: crystal structure of putative alcohol dehedrogenase (yp_298327.1) from2 ralstonia eutropha jmp134 at 2.10 a resolution
51c3r64A_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:nad dependent benzaldehyde dehydrogenase;
PDBTitle: crystal structure of a nad-dependent benzaldehyde dehydrogenase from2 corynebacterium glutamicum
52c2vroB_
not modelled 100.0 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:aldehyde dehydrogenase;
PDBTitle: crystal structure of aldehyde dehydrogenase from2 burkholderia xenovorans lb400
53d1jq5a_
not modelled 100.0 20 Fold:Dehydroquinate synthase-like
Superfamily:Dehydroquinate synthase-like
Family:Iron-containing alcohol dehydrogenase
54c3lnsD_
not modelled 100.0 16 PDB header:oxidoreductase
Chain: D: PDB Molecule:benzaldehyde dehydrogenase;
PDBTitle: benzaldehyde dehydrogenase, a class 3 aldehyde dehydrogenase, with2 bound nadp+ and benzoate adduct
55d1vlua_
not modelled 100.0 16 Fold:ALDH-like
Superfamily:ALDH-like
Family:ALDH-like
56c2h5gA_
not modelled 100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:delta 1-pyrroline-5-carboxylate synthetase;
PDBTitle: crystal structure of human pyrroline-5-carboxylate synthetase
57c1vluB_
not modelled 100.0 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:gamma-glutamyl phosphate reductase;
PDBTitle: crystal structure of gamma-glutamyl phosphate reductase (yor323c) from2 saccharomyces cerevisiae at 2.40 a resolution
58c3uhjE_
not modelled 100.0 22 PDB header:oxidoreductase
Chain: E: PDB Molecule:probable glycerol dehydrogenase;
PDBTitle: crystal structure of a probable glycerol dehydrogenase from2 sinorhizobium meliloti 1021
59d1kq3a_
not modelled 100.0 24 Fold:Dehydroquinate synthase-like
Superfamily:Dehydroquinate synthase-like
Family:Iron-containing alcohol dehydrogenase
60c1ta9A_
not modelled 100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:glycerol dehydrogenase;
PDBTitle: crystal structure of glycerol dehydrogenase from schizosaccharomyces2 pombe
61c3ce9A_
not modelled 100.0 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:glycerol dehydrogenase;
PDBTitle: crystal structure of glycerol dehydrogenase (np_348253.1) from2 clostridium acetobutylicum at 2.37 a resolution
62c3okfA_
not modelled 100.0 19 PDB header:lyase
Chain: A: PDB Molecule:3-dehydroquinate synthase;
PDBTitle: 2.5 angstrom resolution crystal structure of 3-dehydroquinate synthase2 (arob) from vibrio cholerae
63c1xahA_
not modelled 100.0 21 PDB header:lyase
Chain: A: PDB Molecule:3-dehydroquinate synthase;
PDBTitle: crystal structure of staphlyococcus aureus 3-dehydroquinate2 synthase (dhqs) in complex with zn2+ and nad+
64d1sg6a_
not modelled 100.0 18 Fold:Dehydroquinate synthase-like
Superfamily:Dehydroquinate synthase-like
Family:Dehydroquinate synthase, DHQS
65c2gruB_
not modelled 100.0 15 PDB header:lyase
Chain: B: PDB Molecule:2-deoxy-scyllo-inosose synthase;
PDBTitle: crystal structure of 2-deoxy-scyllo-inosose synthase2 complexed with carbaglucose-6-phosphate, nad+ and co2+
66c3clhA_
not modelled 100.0 18 PDB header:lyase
Chain: A: PDB Molecule:3-dehydroquinate synthase;
PDBTitle: crystal structure of 3-dehydroquinate synthase (dhqs)from2 helicobacter pylori
67d1ujna_
not modelled 100.0 17 Fold:Dehydroquinate synthase-like
Superfamily:Dehydroquinate synthase-like
Family:Dehydroquinate synthase, DHQS
68d2jgra1
not modelled 96.8 17 Fold:NAD kinase/diacylglycerol kinase-like
Superfamily:NAD kinase/diacylglycerol kinase-like
Family:Diacylglycerol kinase-like
69d2bona1
not modelled 96.7 18 Fold:NAD kinase/diacylglycerol kinase-like
Superfamily:NAD kinase/diacylglycerol kinase-like
Family:Diacylglycerol kinase-like
70c3orsD_
not modelled 96.6 18 PDB header:isomerase,biosynthetic protein
Chain: D: PDB Molecule:n5-carboxyaminoimidazole ribonucleotide mutase;
PDBTitle: crystal structure of n5-carboxyaminoimidazole ribonucleotide mutase2 from staphylococcus aureus
71d1o4va_
not modelled 96.4 24 Fold:Flavodoxin-like
Superfamily:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
Family:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
72d1qcza_
not modelled 96.4 26 Fold:Flavodoxin-like
Superfamily:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
Family:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
73d1u11a_
not modelled 96.4 18 Fold:Flavodoxin-like
Superfamily:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
Family:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
74c2fw9A_
not modelled 96.4 18 PDB header:lyase
Chain: A: PDB Molecule:n5-carboxyaminoimidazole ribonucleotide mutase;
PDBTitle: structure of pure (n5-carboxyaminoimidazole ribonucleotide mutase)2 h59f from the acidophilic bacterium acetobacter aceti, at ph 8
75c3lp6D_
not modelled 96.4 21 PDB header:lyase
Chain: D: PDB Molecule:phosphoribosylaminoimidazole carboxylase catalytic subunit;
PDBTitle: crystal structure of rv3275c-e60a from mycobacterium tuberculosis at2 1.7a resolution
76d2p1ra1
not modelled 96.3 17 Fold:NAD kinase/diacylglycerol kinase-like
Superfamily:NAD kinase/diacylglycerol kinase-like
Family:Diacylglycerol kinase-like
77c3rggD_
not modelled 96.1 24 PDB header:lyase
Chain: D: PDB Molecule:phosphoribosylaminoimidazole carboxylase, pure protein;
PDBTitle: crystal structure of treponema denticola pure bound to air
78d1k75a_
not modelled 95.9 16 Fold:ALDH-like
Superfamily:ALDH-like
Family:L-histidinol dehydrogenase HisD
79c2bonB_
not modelled 95.8 18 PDB header:transferase
Chain: B: PDB Molecule:lipid kinase;
PDBTitle: structure of an escherichia coli lipid kinase (yegs)
80d1u0ta_
not modelled 95.8 27 Fold:NAD kinase/diacylglycerol kinase-like
Superfamily:NAD kinase/diacylglycerol kinase-like
Family:NAD kinase-like
81d1ewka_
not modelled 95.8 10 Fold:Periplasmic binding protein-like I
Superfamily:Periplasmic binding protein-like I
Family:L-arabinose binding protein-like
82c3trhI_
not modelled 95.8 22 PDB header:lyase
Chain: I: PDB Molecule:phosphoribosylaminoimidazole carboxylase
PDBTitle: structure of a phosphoribosylaminoimidazole carboxylase catalytic2 subunit (pure) from coxiella burnetii
83d1xmpa_
not modelled 95.7 22 Fold:Flavodoxin-like
Superfamily:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
Family:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
84c2qv7A_
not modelled 95.5 27 PDB header:transferase
Chain: A: PDB Molecule:diacylglycerol kinase dgkb;
PDBTitle: crystal structure of diacylglycerol kinase dgkb in complex with adp2 and mg
85d1qo0a_
not modelled 95.2 10 Fold:Periplasmic binding protein-like I
Superfamily:Periplasmic binding protein-like I
Family:L-arabinose binding protein-like
86c3s40C_
not modelled 95.2 19 PDB header:transferase
Chain: C: PDB Molecule:diacylglycerol kinase;
PDBTitle: the crystal structure of a diacylglycerol kinases from bacillus2 anthracis str. sterne
87c3h5lB_
not modelled 94.7 19 PDB header:transport protein
Chain: B: PDB Molecule:putative branched-chain amino acid abc
PDBTitle: crystal structure of a putative branched-chain amino acid2 abc transporter from silicibacter pomeroyi
88c2h31A_
not modelled 94.7 13 PDB header:ligase, lyase
Chain: A: PDB Molecule:multifunctional protein ade2;
PDBTitle: crystal structure of human paics, a bifunctional carboxylase and2 synthetase in purine biosynthesis
89c3q41B_
not modelled 93.9 11 PDB header:transport protein
Chain: B: PDB Molecule:glutamate [nmda] receptor subunit zeta-1;
PDBTitle: crystal structure of the glun1 n-terminal domain (ntd)
90c3i45A_
not modelled 93.6 13 PDB header:signaling protein
Chain: A: PDB Molecule:twin-arginine translocation pathway signal protein;
PDBTitle: crystal structure of putative twin-arginine translocation pathway2 signal protein from rhodospirillum rubrum atcc 11170
91d2qv7a1
not modelled 93.4 29 Fold:NAD kinase/diacylglycerol kinase-like
Superfamily:NAD kinase/diacylglycerol kinase-like
Family:Diacylglycerol kinase-like
92c2j37W_
not modelled 93.3 21 PDB header:ribosome
Chain: W: PDB Molecule:signal recognition particle 54 kda protein
PDBTitle: model of mammalian srp bound to 80s rncs
93d1gvea_
not modelled 93.3 13 Fold:TIM beta/alpha-barrel
Superfamily:NAD(P)-linked oxidoreductase
Family:Aldo-keto reductases (NADP)
94d1vh3a_
not modelled 93.2 19 Fold:Nucleotide-diphospho-sugar transferases
Superfamily:Nucleotide-diphospho-sugar transferases
Family:Cytidylytransferase
95c2j289_
not modelled 92.8 19 PDB header:ribosome
Chain: 9: PDB Molecule:signal recognition particle 54;
PDBTitle: model of e. coli srp bound to 70s rncs
96c2ywxA_
not modelled 92.8 27 PDB header:lyase
Chain: A: PDB Molecule:phosphoribosylaminoimidazole carboxylase catalytic subunit;
PDBTitle: crystal structure of phosphoribosylaminoimidazole carboxylase2 catalytic subunit from methanocaldococcus jannaschii
97c3snrA_
not modelled 92.6 14 PDB header:transport protein
Chain: A: PDB Molecule:extracellular ligand-binding receptor;
PDBTitle: rpd_1889 protein, an extracellular ligand-binding receptor from2 rhodopseudomonas palustris.
98c2iy3A_
not modelled 92.1 19 PDB header:rna-binding
Chain: A: PDB Molecule:signal recognition particle protein ffh;
PDBTitle: structure of the e. coli signal recognition particle2 bound to a translating ribosome
99c2an1D_
not modelled 92.0 25 PDB header:transferase
Chain: D: PDB Molecule:putative kinase;
PDBTitle: structural genomics, the crystal structure of a putative kinase from2 salmonella typhimurim lt2
100c3ip5A_
not modelled 91.7 15 PDB header:transport protein
Chain: A: PDB Molecule:abc transporter, substrate binding protein (amino acid);
PDBTitle: structure of atu2422-gaba receptor in complex with alanine
101c3dm5A_
not modelled 91.7 19 PDB header:rna binding protein, transport protein
Chain: A: PDB Molecule:signal recognition 54 kda protein;
PDBTitle: structures of srp54 and srp19, the two proteins assembling2 the ribonucleic core of the signal recognition particle3 from the archaeon pyrococcus furiosus.
102c2e4wA_
not modelled 91.6 4 PDB header:signaling protein
Chain: A: PDB Molecule:metabotropic glutamate receptor 3;
PDBTitle: crystal structure of the extracellular region of the group ii2 metabotropic glutamate receptor complexed with 1s,3s-acpd
103c3i09A_
not modelled 91.4 18 PDB header:transport protein
Chain: A: PDB Molecule:periplasmic branched-chain amino acid-binding protein;
PDBTitle: crystal structure of a periplasmic binding protein (bma2936) from2 burkholderia mallei at 1.80 a resolution
104c3cf4G_
not modelled 91.1 19 PDB header:oxidoreductase
Chain: G: PDB Molecule:acetyl-coa decarboxylase/synthase epsilon subunit;
PDBTitle: structure of the codh component of the m. barkeri acds complex
105c3dcjA_
not modelled 91.1 11 PDB header:transferase
Chain: A: PDB Molecule:probable 5'-phosphoribosylglycinamide
PDBTitle: crystal structure of glycinamide formyltransferase (purn)2 from mycobacterium tuberculosis in complex with 5-methyl-5,3 6,7,8-tetrahydrofolic acid derivative
106c3sg0A_
not modelled 90.9 14 PDB header:signaling protein
Chain: A: PDB Molecule:extracellular ligand-binding receptor;
PDBTitle: the crystal structure of an extracellular ligand-binding receptor from2 rhodopseudomonas palustris haa2
107c3eafA_
not modelled 90.8 12 PDB header:transport protein
Chain: A: PDB Molecule:abc transporter, substrate binding protein;
PDBTitle: crystal structure of abc transporter, substrate binding protein2 aeropyrum pernix
108c3tqrA_
not modelled 90.2 15 PDB header:transferase
Chain: A: PDB Molecule:phosphoribosylglycinamide formyltransferase;
PDBTitle: structure of the phosphoribosylglycinamide formyltransferase (purn) in2 complex with ches from coxiella burnetii
109d1pyfa_
not modelled 90.2 12 Fold:TIM beta/alpha-barrel
Superfamily:NAD(P)-linked oxidoreductase
Family:Aldo-keto reductases (NADP)
110d1ovma1
not modelled 90.0 18 Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
111c3n0wA_
not modelled 89.9 12 PDB header:transport protein
Chain: A: PDB Molecule:abc branched chain amino acid family transporter,
PDBTitle: crystal structure of a branched chain amino acid abc transporter2 periplasmic ligand-binding protein (bxe_c0949) from burkholderia3 xenovorans lb400 at 1.88 a resolution
112d1a9xa4
not modelled 89.9 23 Fold:PreATP-grasp domain
Superfamily:PreATP-grasp domain
Family:BC N-terminal domain-like
113c1qzwC_
not modelled 89.6 24 PDB header:signaling protein/rna
Chain: C: PDB Molecule:signal recognition 54 kda protein;
PDBTitle: crystal structure of the complete core of archaeal srp and2 implications for inter-domain communication
114d1usga_
not modelled 89.3 14 Fold:Periplasmic binding protein-like I
Superfamily:Periplasmic binding protein-like I
Family:L-arabinose binding protein-like
115d1pfka_
not modelled 89.3 19 Fold:Phosphofructokinase
Superfamily:Phosphofructokinase
Family:Phosphofructokinase
116c2q5cA_
not modelled 89.2 14 PDB header:transcription
Chain: A: PDB Molecule:ntrc family transcriptional regulator;
PDBTitle: crystal structure of ntrc family transcriptional regulator from2 clostridium acetobutylicum
117d2ji7a1
not modelled 89.2 17 Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
118c3rfqC_
not modelled 88.6 18 PDB header:biosynthetic protein
Chain: C: PDB Molecule:pterin-4-alpha-carbinolamine dehydratase moab2;
PDBTitle: crystal structure of pterin-4-alpha-carbinolamine dehydratase moab22 from mycobacterium marinum
119d2liva_
not modelled 88.6 14 Fold:Periplasmic binding protein-like I
Superfamily:Periplasmic binding protein-like I
Family:L-arabinose binding protein-like
120d1y5ea1
not modelled 88.4 21 Fold:Molybdenum cofactor biosynthesis proteins
Superfamily:Molybdenum cofactor biosynthesis proteins
Family:MogA-like

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0