Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	R	Q	T	K	T	G	I	L	L	A	N	L	G	T	P	D	A	P	T	P	E	A	V	K	R	Y	L	K	Q	F	L	S	D	R	R	V	V	D	T	S	R	L	L	W	W	P	L	L	R	G	V	I	L	P	L	R	S	P	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	A	K	L	Y	A	S	V	W	M	E	G	G	S	P	L	M	V	Y	S	R	Q	Q	Q	Q	A	L	A	Q	R	L	P	E	M	P	V	A	L	G	M	S	Y	G	S	P	S	L	E	S	A	V	D	E	L	L	A	E	H	V	D
Secondary structure
SS confidence
Disorder											?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		H	I	V	V	L	P	L	Y	P	Q	F	S	C	S	T	V	G	A	V	W	D	E	L	A	R	I	L	A	R	K	R	S	I	P	G	I	S	F	I	R	D	Y	A	D	N	H	D	Y	I	N	A	L	A	N	S	V	R	A	S	F
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	K	H	G	E	P	D	L	L	L	L	S	Y	H	G	I	P	Q	R	Y	A	D	E	G	D	D	Y	P	Q	R	C	R	T	T	T	R	E	L	A	S	A	L	G	M	A	P	E	K	V	M	M	T	F	Q	S	R	F	G	R	E
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		P	W	L	M	P	Y	T	D	E	T	L	K	M	L	G	E	K	G	V	G	H	I	Q	V	M	C	P	G	F	A	A	D	C	L	E	T	L	E	E	I	A	E	Q	N	R	E	V	F	L	G	A	G	G	K	K	Y	E	Y	I	P
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320
Sequence		A	L	N	A	T	P	E	H	I	E	M	M	A	N	L	V	A	A	Y	R
Secondary structure
SS confidence
Disorder																			?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1lbq chain A Region: 3 - 319 Aligned: 308 Modelled: 313 Confidence: 100.0% Identity: 27% Fold: Chelatase-like Superfamily: Chelatase Family: Ferrochelatase Phyre2 PDB 2hrc chain A domain 1 Region: 2 - 319 Aligned: 310 Modelled: 316 Confidence: 100.0% Identity: 28% Fold: Chelatase-like Superfamily: Chelatase Family: Ferrochelatase Phyre2 PDB 2hk6 chain A domain 1 Region: 3 - 319 Aligned: 293 Modelled: 301 Confidence: 100.0% Identity: 25% Fold: Chelatase-like Superfamily: Chelatase Family: Ferrochelatase Phyre2 PDB 2xvz chain A Region: 4 - 318 Aligned: 239 Modelled: 259 Confidence: 100.0% Identity: 17% PDB header:metal binding protein Chain: A: PDB Molecule:chelatase, putative; PDBTitle: cobalt chelatase cbik (periplasmatic) from desulvobrio2 vulgaris hildenborough (co-crystallized with cobalt) Phyre2 PDB 1qgo chain A Region: 5 - 318 Aligned: 235 Modelled: 255 Confidence: 100.0% Identity: 15% Fold: Chelatase-like Superfamily: Chelatase Family: Cobalt chelatase CbiK Phyre2 PDB 2jh3 chain C Region: 6 - 320 Aligned: 242 Modelled: 257 Confidence: 99.8% Identity: 17% PDB header:ribosomal protein Chain: C: PDB Molecule:ribosomal protein s2-related protein; PDBTitle: the crystal structure of dr2241 from deinococcus2 radiodurans at 1.9 a resolution reveals a multi-domain3 protein with structural similarity to chelatases but also4 with two additional novel domains Phyre2 PDB 3lyh chain B Region: 186 - 318 Aligned: 114 Modelled: 133 Confidence: 99.5% Identity: 13% PDB header:lyase Chain: B: PDB Molecule:cobalamin (vitamin b12) biosynthesis cbix protein; PDBTitle: crystal structure of putative cobalamin (vitamin b12) biosynthesis2 cbix protein (yp_958415.1) from marinobacter aquaeolei vt8 at 1.60 a3 resolution Phyre2 PDB 1tjn chain A Region: 186 - 318 Aligned: 116 Modelled: 131 Confidence: 99.2% Identity: 16% PDB header:lyase Chain: A: PDB Molecule:sirohydrochlorin cobaltochelatase; PDBTitle: crystal structure of hypothetical protein af0721 from archaeoglobus2 fulgidus Phyre2 PDB 1tjn chain A Region: 186 - 318 Aligned: 116 Modelled: 133 Confidence: 99.2% Identity: 16% Fold: Chelatase-like Superfamily: Chelatase Family: CbiX-like Phyre2 PDB 2csu chain B Region: 245 - 303 Aligned: 57 Modelled: 59 Confidence: 87.0% Identity: 23% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:457aa long hypothetical protein; PDBTitle: crystal structure of ph0766 from pyrococcus horikoshii ot3 Phyre2 PDB 2csu chain A domain 1 Region: 247 - 301 Aligned: 53 Modelled: 55 Confidence: 85.1% Identity: 25% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: CoA-binding domain Phyre2 PDB 3ke8 chain A Region: 133 - 221 Aligned: 87 Modelled: 89 Confidence: 75.1% Identity: 15% PDB header:oxidoreductase Chain: A: PDB Molecule:4-hydroxy-3-methylbut-2-enyl diphosphate PDBTitle: crystal structure of isph:hmbpp-complex Phyre2 PDB 2d59 chain A domain 1 Region: 247 - 302 Aligned: 44 Modelled: 56 Confidence: 72.6% Identity: 16% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: CoA-binding domain Phyre2 PDB 1efp chain B Region: 74 - 156 Aligned: 82 Modelled: 83 Confidence: 71.8% Identity: 15% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: ETFP subunits Phyre2 PDB 3ewb chain X Region: 73 - 269 Aligned: 178 Modelled: 192 Confidence: 70.7% Identity: 13% PDB header:transferase Chain: X: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of n-terminal domain of putative 2-2 isopropylmalate synthase from listeria monocytogenes Phyre2 PDB 3hjt chain B Region: 160 - 318 Aligned: 138 Modelled: 158 Confidence: 68.4% Identity: 16% PDB header:cell adhesion, transport protein Chain: B: PDB Molecule:lmb; PDBTitle: structure of laminin binding protein (lmb) of streptococcus2 agalactiae a bifunctional protein with adhesin and metal3 transporting activity Phyre2 PDB 1yj5 chain A domain 1 Region: 241 - 305 Aligned: 65 Modelled: 65 Confidence: 67.1% Identity: 12% Fold: HAD-like Superfamily: HAD-like Family: phosphatase domain of polynucleotide kinase Phyre2 PDB 1o94 chain C Region: 74 - 156 Aligned: 81 Modelled: 83 Confidence: 67.0% Identity: 14% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: ETFP subunits Phyre2 PDB 3cls chain C domain 1 Region: 74 - 156 Aligned: 82 Modelled: 83 Confidence: 66.6% Identity: 12% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: ETFP subunits Phyre2 PDB 1pzx chain A Region: 103 - 192 Aligned: 87 Modelled: 90 Confidence: 66.4% Identity: 11% Fold: DAK1/DegV-like Superfamily: DAK1/DegV-like Family: DegV-like Phyre2 1 d1lbqa_ 2 d2hrca1 3 d2hk6a1 4 c2xvzA_ 5 d1qgoa_ 6 c2jh3C_ 7 c3lyhB_ 8 c1tjnA_ 9 d1tjna_ 10 c2csuB_ 11 d2csua1 12 c3ke8A_ 13 d2d59a1 14 d1efpb_ 15 c3ewbX_ 16 c3hjtB_ 17 d1yj5a1 18 d1o94c_ 19 d3clsc1 20 d1pzxa_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1lbqa_ 100.0 27 Fold:Chelatase-like Superfamily:Chelatase Family:Ferrochelatase 2 d2hrca1 100.0 28 Fold:Chelatase-like Superfamily:Chelatase Family:Ferrochelatase 3 d2hk6a1 100.0 25 Fold:Chelatase-like Superfamily:Chelatase Family:Ferrochelatase 4 c2xvzA_ 100.0 17 PDB header:metal binding protein Chain: A: PDB Molecule:chelatase, putative; PDBTitle: cobalt chelatase cbik (periplasmatic) from desulvobrio2 vulgaris hildenborough (co-crystallized with cobalt) 5 d1qgoa_ 100.0 15 Fold:Chelatase-like Superfamily:Chelatase Family:Cobalt chelatase CbiK 6 c2jh3C_ 99.8 17 PDB header:ribosomal protein Chain: C: PDB Molecule:ribosomal protein s2-related protein; PDBTitle: the crystal structure of dr2241 from deinococcus2 radiodurans at 1.9 a resolution reveals a multi-domain3 protein with structural similarity to chelatases but also4 with two additional novel domains 7 c3lyhB_ 99.5 13 PDB header:lyase Chain: B: PDB Molecule:cobalamin (vitamin b12) biosynthesis cbix protein; PDBTitle: crystal structure of putative cobalamin (vitamin b12) biosynthesis2 cbix protein (yp_958415.1) from marinobacter aquaeolei vt8 at 1.60 a3 resolution 8 c1tjnA_ 99.2 16 PDB header:lyase Chain: A: PDB Molecule:sirohydrochlorin cobaltochelatase; PDBTitle: crystal structure of hypothetical protein af0721 from archaeoglobus2 fulgidus 9 d1tjna_ 99.2 16 Fold:Chelatase-like Superfamily:Chelatase Family:CbiX-like 10 c2csuB_ 87.0 23 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:457aa long hypothetical protein; PDBTitle: crystal structure of ph0766 from pyrococcus horikoshii ot3 11 d2csua1 85.1 25 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 12 c3ke8A_ 75.1 15 PDB header:oxidoreductase Chain: A: PDB Molecule:4-hydroxy-3-methylbut-2-enyl diphosphate PDBTitle: crystal structure of isph:hmbpp-complex 13 d2d59a1 72.6 16 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 14 d1efpb_ 71.8 15 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ETFP subunits 15 c3ewbX_ 70.7 13 PDB header:transferase Chain: X: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of n-terminal domain of putative 2-2 isopropylmalate synthase from listeria monocytogenes 16 c3hjtB_ 68.4 16 PDB header:cell adhesion, transport protein Chain: B: PDB Molecule:lmb; PDBTitle: structure of laminin binding protein (lmb) of streptococcus2 agalactiae a bifunctional protein with adhesin and metal3 transporting activity 17 d1yj5a1 67.1 12 Fold:HAD-like Superfamily:HAD-like Family:phosphatase domain of polynucleotide kinase 18 d1o94c_ 67.0 14 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ETFP subunits 19 d3clsc1 66.6 12 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ETFP subunits 20 d1pzxa_ 66.4 11 Fold:DAK1/DegV-like Superfamily:DAK1/DegV-like Family:DegV-like 21 c2qniA_ not modelled 66.3 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein atu0299; PDBTitle: crystal structure of uncharacterized protein atu0299 22 d1tipa_ not modelled 65.4 13 Fold:Phosphoglycerate mutase-like Superfamily:Phosphoglycerate mutase-like Family:6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain 23 d1k6ma2 not modelled 65.4 14 Fold:Phosphoglycerate mutase-like Superfamily:Phosphoglycerate mutase-like Family:6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain 24 c2yv2A_ not modelled 63.3 12 PDB header:ligase Chain: A: PDB Molecule:succinyl-coa synthetase alpha chain; PDBTitle: crystal structure of succinyl-coa synthetase alpha chain from2 aeropyrum pernix k1 25 c3navB_ not modelled 62.0 15 PDB header:lyase Chain: B: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961 26 c2nu8D_ not modelled 61.8 14 PDB header:ligase Chain: D: PDB Molecule:succinyl-coa ligase [adp-forming] subunit alpha; PDBTitle: c123at mutant of e. coli succinyl-coa synthetase 27 c2ov3A_ not modelled 61.8 13 PDB header:transport protein Chain: A: PDB Molecule:periplasmic binding protein component of an abc PDBTitle: crystal structure of 138-173 znua deletion mutant plus zinc2 bound 28 c3lupA_ not modelled 61.6 20 PDB header:structure genomics, unknown function Chain: A: PDB Molecule:degv family protein; PDBTitle: crystal structure of fatty acid binding degv family protein sag13422 from streptococcus agalactiae 29 c3ha2B_ not modelled 59.8 10 PDB header:oxidoreductase Chain: B: PDB Molecule:nadph-quinone reductase; PDBTitle: crystal structure of protein (nadph-quinone reductase) from2 p.pentosaceus, northeast structural genomics consortium target ptr24a 30 c2p10D_ not modelled 59.0 15 PDB header:hydrolase Chain: D: PDB Molecule:mll9387 protein; PDBTitle: crystal structure of a putative phosphonopyruvate hydrolase (mll9387)2 from mesorhizobium loti maff303099 at 2.15 a resolution 31 c1k6mA_ not modelled 58.9 17 PDB header:transferase, hydrolase Chain: A: PDB Molecule:6-phosphofructo-2-kinase/fructose-2,6- PDBTitle: crystal structure of human liver 6-phosphofructo-2-2 kinase/fructose-2,6-bisphosphatase 32 c2fpgA_ not modelled 58.0 4 PDB header:ligase Chain: A: PDB Molecule:succinyl-coa ligase [gdp-forming] alpha-chain, PDBTitle: crystal structure of pig gtp-specific succinyl-coa2 synthetase in complex with gdp 33 d1bifa2 not modelled 57.8 13 Fold:Phosphoglycerate mutase-like Superfamily:Phosphoglycerate mutase-like Family:6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain 34 d1g01a_ not modelled 56.4 22 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-glycanases 35 c3d4iD_ not modelled 56.0 16 PDB header:hydrolase Chain: D: PDB Molecule:sts-2 protein; PDBTitle: crystal structure of the 2h-phosphatase domain of sts-2 36 d2p10a1 not modelled 54.7 15 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Mll9387-like 37 c3ff4A_ not modelled 53.7 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterized protein chu_1412 38 c2ekcA_ not modelled 53.2 16 PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5 39 d1y81a1 not modelled 53.0 27 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 40 d1qzua_ not modelled 51.0 25 Fold:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Superfamily:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Family:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD 41 c3dnfB_ not modelled 50.8 18 PDB header:oxidoreductase Chain: B: PDB Molecule:4-hydroxy-3-methylbut-2-enyl diphosphate reductase; PDBTitle: structure of (e)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase,2 the terminal enzyme of the non-mevalonate pathway 42 d1h2ea_ not modelled 50.4 14 Fold:Phosphoglycerate mutase-like Superfamily:Phosphoglycerate mutase-like Family:Cofactor-dependent phosphoglycerate mutase 43 c3zvmA_ not modelled 46.7 12 PDB header:hydrolase/transferase/dna Chain: A: PDB Molecule:bifunctional polynucleotide phosphatase/kinase; PDBTitle: the structural basis for substrate recognition by mammalian2 polynucleotide kinase 3' phosphatase 44 c3nyiA_ not modelled 46.4 12 PDB header:lipid binding protein Chain: A: PDB Molecule:fat acid-binding protein; PDBTitle: the crystal structure of a fat acid (stearic acid)-binding protein2 from eubacterium ventriosum atcc 27560. 45 c3c7tB_ not modelled 45.6 16 PDB header:hydrolase Chain: B: PDB Molecule:ecdysteroid-phosphate phosphatase; PDBTitle: crystal structure of the ecdysone phosphate phosphatase, eppase, from2 bombix mori in complex with tungstate 46 d1nh8a2 not modelled 45.5 13 Fold:Ferredoxin-like Superfamily:GlnB-like Family:ATP phosphoribosyltransferase (ATP-PRTase, HisG), regulatory C-terminal domain 47 d1fzta_ not modelled 45.4 10 Fold:Phosphoglycerate mutase-like Superfamily:Phosphoglycerate mutase-like Family:Cofactor-dependent phosphoglycerate mutase 48 d1qopa_ not modelled 45.1 16 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 49 c1qzuB_ not modelled 44.7 25 PDB header:lyase Chain: B: PDB Molecule:hypothetical protein mds018; PDBTitle: crystal structure of human phosphopantothenoylcysteine decarboxylase 50 d1ujpa_ not modelled 42.9 13 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 51 c3mwdB_ not modelled 42.9 12 PDB header:transferase Chain: B: PDB Molecule:atp-citrate synthase; PDBTitle: truncated human atp-citrate lyase with citrate bound 52 c1oi7A_ not modelled 42.7 12 PDB header:synthetase Chain: A: PDB Molecule:succinyl-coa synthetase alpha chain; PDBTitle: the crystal structure of succinyl-coa synthetase alpha2 subunit from thermus thermophilus 53 d1psza_ not modelled 41.9 12 Fold:Chelatase-like Superfamily:"Helical backbone" metal receptor Family:TroA-like 54 d1v9ca_ not modelled 39.9 14 Fold:Flavodoxin-like Superfamily:Precorrin-8X methylmutase CbiC/CobH Family:Precorrin-8X methylmutase CbiC/CobH 55 c3jr7A_ not modelled 39.9 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized egv family protein cog1307; PDBTitle: the crystal structure of the protein of degv family cog1307 with2 unknown function from ruminococcus gnavus atcc 29149 56 c3fdjA_ not modelled 38.8 10 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:degv family protein; PDBTitle: the structure of a degv family protein from eubacterium eligens. 57 c2duwA_ not modelled 38.7 16 PDB header:ligand binding protein Chain: A: PDB Molecule:putative coa-binding protein; PDBTitle: solution structure of putative coa-binding protein of2 klebsiella pneumoniae 58 d1yqha1 not modelled 37.2 15 Fold:Ferredoxin-like Superfamily:MTH1187/YkoF-like Family:MTH1187-like 59 c3pl5A_ not modelled 37.1 9 PDB header:lipid binding protein Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: fatty acid binding protein 60 c3ipwA_ not modelled 36.4 10 PDB header:hydrolase Chain: A: PDB Molecule:hydrolase tatd family protein; PDBTitle: crystal structure of hydrolase tatd family protein from entamoeba2 histolytica 61 c2yv1A_ not modelled 36.3 12 PDB header:ligase Chain: A: PDB Molecule:succinyl-coa ligase [adp-forming] subunit alpha; PDBTitle: crystal structure of succinyl-coa synthetase alpha chain from2 methanocaldococcus jannaschii dsm 2661 62 d1iuka_ not modelled 36.0 16 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 63 d1h3da2 not modelled 35.2 25 Fold:Ferredoxin-like Superfamily:GlnB-like Family:ATP phosphoribosyltransferase (ATP-PRTase, HisG), regulatory C-terminal domain 64 c1yj5B_ not modelled 34.2 12 PDB header:transferase Chain: B: PDB Molecule:5' polynucleotide kinase-3' phosphatase catalytic domain; PDBTitle: molecular architecture of mammalian polynucleotide kinase, a dna2 repair enzyme 65 d1vk8a_ not modelled 33.6 13 Fold:Ferredoxin-like Superfamily:MTH1187/YkoF-like Family:MTH1187-like 66 d2hhja1 not modelled 33.2 16 Fold:Phosphoglycerate mutase-like Superfamily:Phosphoglycerate mutase-like Family:Cofactor-dependent phosphoglycerate mutase 67 c3rfaA_ not modelled 32.7 14 PDB header:oxidoreductase Chain: A: PDB Molecule:ribosomal rna large subunit methyltransferase n; PDBTitle: x-ray structure of rlmn from escherichia coli in complex with s-2 adenosylmethionine 68 d1vh3a_ not modelled 32.7 9 Fold:Nucleotide-diphospho-sugar transferases Superfamily:Nucleotide-diphospho-sugar transferases Family:Cytidylytransferase 69 c2hk1D_ not modelled 32.2 7 PDB header:isomerase Chain: D: PDB Molecule:d-psicose 3-epimerase; PDBTitle: crystal structure of d-psicose 3-epimerase (dpease) in the presence of2 d-fructose 70 c2ou4C_ not modelled 32.1 12 PDB header:isomerase Chain: C: PDB Molecule:d-tagatose 3-epimerase; PDBTitle: crystal structure of d-tagatose 3-epimerase from2 pseudomonas cichorii 71 d3er7a1 not modelled 30.2 16 Fold:Cystatin-like Superfamily:NTF2-like Family:Exig0174-like 72 c2a6pA_ not modelled 30.1 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:possible phosphoglycerate mutase gpm2; PDBTitle: structure solution to 2.2 angstrom and functional characterisation of2 the open reading frame rv3214 from mycobacterium tuberculosis 73 c3e2vA_ not modelled 29.3 11 PDB header:hydrolase Chain: A: PDB Molecule:3'-5'-exonuclease; PDBTitle: crystal structure of an uncharacterized amidohydrolase from2 saccharomyces cerevisiae 74 d2ae8a1 not modelled 29.3 14 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:Imidazole glycerol phosphate dehydratase 75 c1o57A_ not modelled 28.8 19 PDB header:dna binding protein Chain: A: PDB Molecule:pur operon repressor; PDBTitle: crystal structure of the purine operon repressor of2 bacillus subtilis 76 d7reqb2 not modelled 28.6 13 Fold:Flavodoxin-like Superfamily:Cobalamin (vitamin B12)-binding domain Family:Cobalamin (vitamin B12)-binding domain 77 d2dlda2 not modelled 28.4 24 Fold:Flavodoxin-like Superfamily:Formate/glycerate dehydrogenase catalytic domain-like Family:Formate/glycerate dehydrogenases, substrate-binding domain 78 d1mgpa_ not modelled 28.1 19 Fold:DAK1/DegV-like Superfamily:DAK1/DegV-like Family:DegV-like 79 c1mgpA_ not modelled 28.1 19 PDB header:lipid binding protein Chain: A: PDB Molecule:hypothetical protein tm841; PDBTitle: hypothetical protein tm841 from thermotoga maritima reveals2 fatty acid binding function 80 d2b8ea1 not modelled 27.6 9 Fold:HAD-like Superfamily:HAD-like Family:Meta-cation ATPase, catalytic domain P 81 d1ycga1 not modelled 27.2 14 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 82 c2i6oA_ not modelled 27.1 15 PDB header:hydrolase Chain: A: PDB Molecule:sulfolobus solfataricus protein tyrosine PDBTitle: crystal structure of the complex of the archaeal sulfolobus2 ptp-fold phosphatase with phosphopeptides n-g-(p)y-k-n 83 d1v37a_ not modelled 26.8 19 Fold:Phosphoglycerate mutase-like Superfamily:Phosphoglycerate mutase-like Family:Cofactor-dependent phosphoglycerate mutase 84 c2ae8C_ not modelled 26.3 14 PDB header:lyase Chain: C: PDB Molecule:imidazoleglycerol-phosphate dehydratase; PDBTitle: crystal structure of imidazoleglycerol-phosphate dehydratase from2 staphylococcus aureus subsp. aureus n315 85 d1e5da1 not modelled 26.3 12 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 86 c3e9eB_ not modelled 25.6 15 PDB header:hydrolase Chain: B: PDB Molecule:zgc:56074; PDBTitle: structure of full-length h11a mutant form of tigar from danio rerio 87 c3dmyA_ not modelled 25.2 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:protein fdra; PDBTitle: crystal structure of a predicated acyl-coa synthetase from e.coli 88 c3bdkB_ not modelled 24.2 20 PDB header:lyase Chain: B: PDB Molecule:d-mannonate dehydratase; PDBTitle: crystal structure of streptococcus suis mannonate2 dehydratase complexed with substrate analogue 89 c2hmcA_ not modelled 23.8 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: the crystal structure of dihydrodipicolinate synthase dapa from2 agrobacterium tumefaciens 90 c3rpeA_ not modelled 23.7 14 PDB header:oxidoreductase Chain: A: PDB Molecule:modulator of drug activity b; PDBTitle: 1.1 angstrom crystal structure of putative modulator of drug activity2 (mdab) from yersinia pestis co92. 91 c3dcyA_ not modelled 23.5 13 PDB header:apoptosis regulator Chain: A: PDB Molecule:regulator protein; PDBTitle: crystal structure a tp53-induced glycolysis and apoptosis2 regulator protein from homo sapiens. 92 d1lxna_ not modelled 23.0 16 Fold:Ferredoxin-like Superfamily:MTH1187/YkoF-like Family:MTH1187-like 93 d1efvb_ not modelled 22.6 15 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ETFP subunits 94 c3eywA_ not modelled 21.7 13 PDB header:transport protein Chain: A: PDB Molecule:c-terminal domain of glutathione-regulated potassium-efflux PDBTitle: crystal structure of the c-terminal domain of e. coli kefc in complex2 with keff 95 d1pq4a_ not modelled 21.7 12 Fold:Chelatase-like Superfamily:"Helical backbone" metal receptor Family:TroA-like 96 d1fpza_ not modelled 21.5 12 Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Dual specificity phosphatase-like 97 d1bqca_ not modelled 21.4 15 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-glycanases 98 c3pnnA_ not modelled 21.2 13 PDB header:transferase Chain: A: PDB Molecule:conserved domain protein; PDBTitle: the crystal structure of a glycosyltransferase from porphyromonas2 gingivalis w83 99 c3guwB_ not modelled 21.0 15 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein af_1765; PDBTitle: crystal structure of the tatd-like protein (af1765) from2 archaeoglobus fulgidus, northeast structural genomics3 consortium target gr121 100 c2c4kD_ not modelled 20.8 13 PDB header:regulatory protein Chain: D: PDB Molecule:phosphoribosyl pyrophosphate synthetase- PDBTitle: crystal structure of human phosphoribosylpyrophosphate2 synthetase-associated protein 39 (pap39) 101 d1vica_ not modelled 20.6 8 Fold:Nucleotide-diphospho-sugar transferases Superfamily:Nucleotide-diphospho-sugar transferases Family:Cytidylytransferase

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0