Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	R	I	L	V	L	G	V	G	N	I	L	L	T	D	E	A	I	G	V	R	I	V	E	A	L	E	Q	R	Y	I	L	P	D	Y	V	E	I	L	D	G	G	T	A	G	M	E	L	L	G	D	M	A	N	R	D	H	L	I	I
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	D	A	I	V	S	K	K	N	A	P	G	T	M	M	I	L	R	D	E	E	V	P	A	L	F	T	N	K	I	S	P	H	Q	L	G	L	A	D	V	L	S	A	L	R	F	T	G	E	F	P	K	K	L	T	L	V	G	V	I
Secondary structure
SS confidence
Disorder																							?		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.
Sequence		P	E	S	L	E	P	H	I	G	L	T	P	T	V	E	A	M	I	E	P	A	L	E	Q	V	L	A	A	L	R	E	S	G	V	E	A	I	P	R	E	A	I	H	D
Secondary structure
SS confidence
Disorder																																							?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1cfz chain A Region: 1 - 160 Aligned: 160 Modelled: 160 Confidence: 100.0% Identity: 99% Fold: Phosphorylase/hydrolase-like Superfamily: HybD-like Family: Hydrogenase maturating endopeptidase HybD Phyre2 PDB 2e85 chain B Region: 1 - 160 Aligned: 152 Modelled: 160 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: B: PDB Molecule:hydrogenase 3 maturation protease; PDBTitle: crystal structure of the hydrogenase 3 maturation protease Phyre2 PDB 3pu6 chain A Region: 1 - 152 Aligned: 132 Modelled: 147 Confidence: 100.0% Identity: 18% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: the crystal structure of an uncharacterized protein from wolinella2 succinogenes Phyre2 PDB 1c8b chain A Region: 2 - 70 Aligned: 69 Modelled: 69 Confidence: 96.2% Identity: 28% Fold: Phosphorylase/hydrolase-like Superfamily: HybD-like Family: Germination protease Phyre2 PDB 2pth chain A Region: 1 - 152 Aligned: 138 Modelled: 145 Confidence: 94.8% Identity: 21% Fold: Phosphorylase/hydrolase-like Superfamily: Peptidyl-tRNA hydrolase-like Family: Peptidyl-tRNA hydrolase-like Phyre2 PDB 1t0i chain A Region: 1 - 149 Aligned: 144 Modelled: 149 Confidence: 88.3% Identity: 9% Fold: Flavodoxin-like Superfamily: Flavoproteins Family: NADPH-dependent FMN reductase Phyre2 PDB 1ks9 chain A Region: 1 - 60 Aligned: 50 Modelled: 60 Confidence: 86.3% Identity: 32% PDB header:oxidoreductase Chain: A: PDB Molecule:2-dehydropantoate 2-reductase; PDBTitle: ketopantoate reductase from escherichia coli Phyre2 PDB 2ofp chain B Region: 1 - 60 Aligned: 50 Modelled: 57 Confidence: 85.5% Identity: 32% PDB header:oxidoreductase Chain: B: PDB Molecule:ketopantoate reductase; PDBTitle: crystal structure of escherichia coli ketopantoate2 reductase in a ternary complex with nadp+ and pantoate Phyre2 PDB 3cky chain A Region: 1 - 61 Aligned: 51 Modelled: 61 Confidence: 85.4% Identity: 24% PDB header:oxidoreductase Chain: A: PDB Molecule:2-hydroxymethyl glutarate dehydrogenase; PDBTitle: structural and kinetic properties of a beta-hydroxyacid dehydrogenase2 involved in nicotinate fermentation Phyre2 PDB 1n1e chain A domain 2 Region: 1 - 60 Aligned: 50 Modelled: 60 Confidence: 84.6% Identity: 18% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain Phyre2 PDB 3v2i chain A Region: 1 - 33 Aligned: 33 Modelled: 33 Confidence: 84.5% Identity: 27% PDB header:hydrolase Chain: A: PDB Molecule:peptidyl-trna hydrolase; PDBTitle: structure of a peptidyl-trna hydrolase (pth) from burkholderia2 thailandensis Phyre2 PDB 1txg chain A domain 2 Region: 1 - 60 Aligned: 50 Modelled: 53 Confidence: 83.3% Identity: 22% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain Phyre2 PDB 3lcm chain B Region: 1 - 72 Aligned: 68 Modelled: 72 Confidence: 82.9% Identity: 19% PDB header:oxidoreductase Chain: B: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of smu.1420 from streptococcus mutans ua159 Phyre2 PDB 2c42 chain A domain 3 Region: 3 - 133 Aligned: 124 Modelled: 131 Confidence: 82.8% Identity: 9% Fold: TK C-terminal domain-like Superfamily: TK C-terminal domain-like Family: Pyruvate-ferredoxin oxidoreductase, PFOR, domain II Phyre2 PDB 1mv8 chain A domain 2 Region: 1 - 49 Aligned: 39 Modelled: 46 Confidence: 82.6% Identity: 28% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain Phyre2 PDB 2zkl chain A Region: 1 - 73 Aligned: 65 Modelled: 73 Confidence: 82.4% Identity: 17% PDB header:isomerase Chain: A: PDB Molecule:capsular polysaccharide synthesis enzyme cap5f; PDBTitle: crystal structure of capsular polysaccharide assembling protein capf2 from staphylococcus aureus Phyre2 PDB 1txg chain A Region: 1 - 60 Aligned: 50 Modelled: 60 Confidence: 82.4% Identity: 26% PDB header:oxidoreductase Chain: A: PDB Molecule:glycerol-3-phosphate dehydrogenase [nad(p)+]; PDBTitle: structure of glycerol-3-phosphate dehydrogenase from archaeoglobus2 fulgidus Phyre2 PDB 3nea chain A Region: 1 - 33 Aligned: 32 Modelled: 32 Confidence: 82.2% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:peptidyl-trna hydrolase; PDBTitle: crystal structure of peptidyl-trna hydrolase from francisella2 tularensis Phyre2 PDB 3ic5 chain A Region: 1 - 62 Aligned: 51 Modelled: 62 Confidence: 82.0% Identity: 20% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative saccharopine dehydrogenase; PDBTitle: n-terminal domain of putative saccharopine dehydrogenase from ruegeria2 pomeroyi. Phyre2 PDB 3g17 chain H Region: 1 - 40 Aligned: 30 Modelled: 40 Confidence: 81.4% Identity: 23% PDB header:structural genomics, unknown function Chain: H: PDB Molecule:similar to 2-dehydropantoate 2-reductase; PDBTitle: structure of putative 2-dehydropantoate 2-reductase from2 staphylococcus aureus Phyre2 1 d1cfza_ 2 c2e85B_ 3 c3pu6A_ 4 d1c8ba_ 5 d2ptha_ 6 d1t0ia_ 7 c1ks9A_ 8 c2ofpB_ 9 c3ckyA_ 10 d1n1ea2 11 c3v2iA_ 12 d1txga2 13 c3lcmB_ 14 d2c42a3 15 d1mv8a2 16 c2zklA_ 17 c1txgA_ 18 c3neaA_ 19 c3ic5A_ 20 c3g17H_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1cfza_ 100.0 99 Fold:Phosphorylase/hydrolase-like Superfamily:HybD-like Family:Hydrogenase maturating endopeptidase HybD 2 c2e85B_ 100.0 19 PDB header:hydrolase Chain: B: PDB Molecule:hydrogenase 3 maturation protease; PDBTitle: crystal structure of the hydrogenase 3 maturation protease 3 c3pu6A_ 100.0 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: the crystal structure of an uncharacterized protein from wolinella2 succinogenes 4 d1c8ba_ 96.2 28 Fold:Phosphorylase/hydrolase-like Superfamily:HybD-like Family:Germination protease 5 d2ptha_ 94.8 21 Fold:Phosphorylase/hydrolase-like Superfamily:Peptidyl-tRNA hydrolase-like Family:Peptidyl-tRNA hydrolase-like 6 d1t0ia_ 88.3 9 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:NADPH-dependent FMN reductase 7 c1ks9A_ 86.3 32 PDB header:oxidoreductase Chain: A: PDB Molecule:2-dehydropantoate 2-reductase; PDBTitle: ketopantoate reductase from escherichia coli 8 c2ofpB_ 85.5 32 PDB header:oxidoreductase Chain: B: PDB Molecule:ketopantoate reductase; PDBTitle: crystal structure of escherichia coli ketopantoate2 reductase in a ternary complex with nadp+ and pantoate 9 c3ckyA_ 85.4 24 PDB header:oxidoreductase Chain: A: PDB Molecule:2-hydroxymethyl glutarate dehydrogenase; PDBTitle: structural and kinetic properties of a beta-hydroxyacid dehydrogenase2 involved in nicotinate fermentation 10 d1n1ea2 84.6 18 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 11 c3v2iA_ 84.5 27 PDB header:hydrolase Chain: A: PDB Molecule:peptidyl-trna hydrolase; PDBTitle: structure of a peptidyl-trna hydrolase (pth) from burkholderia2 thailandensis 12 d1txga2 83.3 22 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 13 c3lcmB_ 82.9 19 PDB header:oxidoreductase Chain: B: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of smu.1420 from streptococcus mutans ua159 14 d2c42a3 82.8 9 Fold:TK C-terminal domain-like Superfamily:TK C-terminal domain-like Family:Pyruvate-ferredoxin oxidoreductase, PFOR, domain II 15 d1mv8a2 82.6 28 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 16 c2zklA_ 82.4 17 PDB header:isomerase Chain: A: PDB Molecule:capsular polysaccharide synthesis enzyme cap5f; PDBTitle: crystal structure of capsular polysaccharide assembling protein capf2 from staphylococcus aureus 17 c1txgA_ 82.4 26 PDB header:oxidoreductase Chain: A: PDB Molecule:glycerol-3-phosphate dehydrogenase [nad(p)+]; PDBTitle: structure of glycerol-3-phosphate dehydrogenase from archaeoglobus2 fulgidus 18 c3neaA_ 82.2 22 PDB header:hydrolase Chain: A: PDB Molecule:peptidyl-trna hydrolase; PDBTitle: crystal structure of peptidyl-trna hydrolase from francisella2 tularensis 19 c3ic5A_ 82.0 20 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative saccharopine dehydrogenase; PDBTitle: n-terminal domain of putative saccharopine dehydrogenase from ruegeria2 pomeroyi. 20 c3g17H_ 81.4 23 PDB header:structural genomics, unknown function Chain: H: PDB Molecule:similar to 2-dehydropantoate 2-reductase; PDBTitle: structure of putative 2-dehydropantoate 2-reductase from2 staphylococcus aureus 21 c2f1kD_ not modelled 79.8 37 PDB header:oxidoreductase Chain: D: PDB Molecule:prephenate dehydrogenase; PDBTitle: crystal structure of synechocystis arogenate dehydrogenase 22 c1ojuA_ not modelled 79.8 12 PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: 2.8 a resolution structure of malate dehydrogenase from2 archaeoglobus fulgidus in complex with etheno-nad. 23 c3l4bG_ not modelled 78.0 20 PDB header:transport protein Chain: G: PDB Molecule:trka k+ channel protien tm1088b; PDBTitle: crystal structure of an octomeric two-subunit trka k+ channel ring2 gating assembly, tm1088a:tm1088b, from thermotoga maritima 24 c3jviA_ not modelled 77.9 22 PDB header:hydrolase Chain: A: PDB Molecule:protein tyrosine phosphatase; PDBTitle: product state mimic crystal structure of protein tyrosine phosphatase2 from entamoeba histolytica 25 d2vapa1 not modelled 77.6 23 Fold:Tubulin nucleotide-binding domain-like Superfamily:Tubulin nucleotide-binding domain-like Family:Tubulin, GTPase domain 26 c3vh1A_ not modelled 77.4 30 PDB header:metal binding protein Chain: A: PDB Molecule:ubiquitin-like modifier-activating enzyme atg7; PDBTitle: crystal structure of saccharomyces cerevisiae atg7 (1-595) 27 d2f1ka2 not modelled 77.2 27 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 28 d1w5fa1 not modelled 76.5 28 Fold:Tubulin nucleotide-binding domain-like Superfamily:Tubulin nucleotide-binding domain-like Family:Tubulin, GTPase domain 29 c3rh0A_ not modelled 76.2 39 PDB header:oxidoreductase Chain: A: PDB Molecule:arsenate reductase; PDBTitle: corynebacterium glutamicum mycothiol/mycoredoxin1-dependent arsenate2 reductase cg_arsc2 30 d1lssa_ not modelled 76.1 23 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Potassium channel NAD-binding domain 31 c3l6dB_ not modelled 76.0 18 PDB header:oxidoreductase Chain: B: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of putative oxidoreductase from pseudomonas putida2 kt2440 32 d1ks9a2 not modelled 75.9 36 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 33 c3vh3A_ not modelled 75.6 29 PDB header:metal binding protein/protein transport Chain: A: PDB Molecule:ubiquitin-like modifier-activating enzyme atg7; PDBTitle: crystal structure of atg7ctd-atg8 complex 34 d1a5za1 not modelled 75.4 25 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:LDH N-terminal domain-like 35 c1w5fA_ not modelled 75.2 28 PDB header:cell division Chain: A: PDB Molecule:cell division protein ftsz; PDBTitle: ftsz, t7 mutated, domain swapped (t. maritima) 36 c2y0dB_ not modelled 74.5 30 PDB header:oxidoreductase Chain: B: PDB Molecule:udp-glucose dehydrogenase; PDBTitle: bcec mutation y10k 37 c1u2pA_ not modelled 72.8 18 PDB header:hydrolase Chain: A: PDB Molecule:low molecular weight protein-tyrosine- PDBTitle: crystal structure of mycobacterium tuberculosis low2 molecular protein tyrosine phosphatase (mptpa) at 1.9a3 resolution 38 c1a5zA_ not modelled 72.7 25 PDB header:oxidoreductase Chain: A: PDB Molecule:l-lactate dehydrogenase; PDBTitle: lactate dehydrogenase from thermotoga maritima (tmldh) 39 c2gf2B_ not modelled 72.6 27 PDB header:oxidoreductase Chain: B: PDB Molecule:3-hydroxyisobutyrate dehydrogenase; PDBTitle: crystal structure of human hydroxyisobutyrate dehydrogenase 40 d1guza1 not modelled 72.4 34 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:LDH N-terminal domain-like 41 c2cwdA_ not modelled 71.6 28 PDB header:hydrolase Chain: A: PDB Molecule:low molecular weight phosphotyrosine protein phosphatase; PDBTitle: crystal structure of tt1001 protein from thermus thermophilus hb8 42 c3gucB_ not modelled 71.4 20 PDB header:transferase Chain: B: PDB Molecule:ubiquitin-like modifier-activating enzyme 5; PDBTitle: human ubiquitin-activating enzyme 5 in complex with amppnp 43 c3qhaB_ not modelled 71.3 23 PDB header:oxidoreductase Chain: B: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of a putative oxidoreductase from mycobacterium2 avium 104 44 c3eywA_ not modelled 70.6 27 PDB header:transport protein Chain: A: PDB Molecule:c-terminal domain of glutathione-regulated potassium-efflux PDBTitle: crystal structure of the c-terminal domain of e. coli kefc in complex2 with keff 45 d1rtta_ not modelled 70.4 10 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:NADPH-dependent FMN reductase 46 d1ojua1 not modelled 70.1 19 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:LDH N-terminal domain-like 47 c4a26B_ not modelled 70.1 29 PDB header:oxidoreductase Chain: B: PDB Molecule:putative c-1-tetrahydrofolate synthase, cytoplasmic; PDBTitle: the crystal structure of leishmania major n5,n10-2 methylenetetrahydrofolate dehydrogenase/cyclohydrolase 48 c3gg2B_ not modelled 69.8 26 PDB header:oxidoreductase Chain: B: PDB Molecule:sugar dehydrogenase, udp-glucose/gdp-mannose PDBTitle: crystal structure of udp-glucose 6-dehydrogenase from2 porphyromonas gingivalis bound to product udp-glucuronate 49 d1jf8a_ not modelled 69.6 19 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 50 d2nqra3 not modelled 69.4 18 Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MoeA central domain-like 51 c2z2vA_ not modelled 68.9 43 PDB header:oxidoreductase Chain: A: PDB Molecule:hypothetical protein ph1688; PDBTitle: crystal structure of l-lysine dehydrogenase from2 hyperthermophilic archaeon pyrococcus horikoshii 52 c2z2jA_ not modelled 68.0 28 PDB header:hydrolase Chain: A: PDB Molecule:peptidyl-trna hydrolase; PDBTitle: crystal structure of peptidyl-trna hydrolase from mycobacterium2 tuberculosis 53 c1y8qD_ not modelled 67.9 29 PDB header:ligase Chain: D: PDB Molecule:ubiquitin-like 2 activating enzyme e1b; PDBTitle: sumo e1 activating enzyme sae1-sae2-mg-atp complex 54 d2b0ja2 not modelled 67.8 23 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 55 c2uyyD_ not modelled 67.2 37 PDB header:cytokine Chain: D: PDB Molecule:n-pac protein; PDBTitle: structure of the cytokine-like nuclear factor n-pac 56 c3nepX_ not modelled 66.8 28 PDB header:oxidoreductase Chain: X: PDB Molecule:malate dehydrogenase; PDBTitle: 1.55a resolution structure of malate dehydrogenase from salinibacter2 ruber 57 c1mv8A_ not modelled 66.6 34 PDB header:oxidoreductase Chain: A: PDB Molecule:gdp-mannose 6-dehydrogenase; PDBTitle: 1.55 a crystal structure of a ternary complex of gdp-mannose2 dehydrogenase from psuedomonas aeruginosa 58 c1w59B_ not modelled 66.1 23 PDB header:cell division Chain: B: PDB Molecule:cell division protein ftsz homolog 1; PDBTitle: ftsz dimer, empty (m. jannaschii) 59 d1gv0a1 not modelled 66.0 34 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:LDH N-terminal domain-like 60 c1zfnA_ not modelled 65.7 16 PDB header:transferase Chain: A: PDB Molecule:adenylyltransferase thif; PDBTitle: structural analysis of escherichia coli thif 61 c3ghyA_ not modelled 65.7 23 PDB header:oxidoreductase Chain: A: PDB Molecule:ketopantoate reductase protein; PDBTitle: crystal structure of a putative ketopantoate reductase from ralstonia2 solanacearum molk2 62 d2cmda1 not modelled 65.4 20 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:LDH N-terminal domain-like 63 c1vkzA_ not modelled 65.3 26 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylamine--glycine ligase; PDBTitle: crystal structure of phosphoribosylamine--glycine ligase (tm1250) from2 thermotoga maritima at 2.30 a resolution 64 c3dojA_ not modelled 65.3 23 PDB header:oxidoreductase Chain: A: PDB Molecule:dehydrogenase-like protein; PDBTitle: structure of glyoxylate reductase 1 from arabidopsis2 (atglyr1) 65 d1pgja2 not modelled 64.7 20 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 66 d9ldta1 not modelled 64.1 31 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:LDH N-terminal domain-like 67 c2h1fB_ not modelled 63.2 14 PDB header:transferase Chain: B: PDB Molecule:lipopolysaccharide heptosyltransferase-1; PDBTitle: e. coli heptosyltransferase waac with adp 68 c3gznB_ not modelled 61.6 24 PDB header:protein binding/ligase Chain: B: PDB Molecule:nedd8-activating enzyme e1 catalytic subunit; PDBTitle: structure of nedd8-activating enzyme in complex with nedd82 and mln4924 69 c2gi4A_ not modelled 61.5 30 PDB header:hydrolase Chain: A: PDB Molecule:possible phosphotyrosine protein phosphatase; PDBTitle: solution structure of the low molecular weight protein2 tyrosine phosphatase from campylobacter jejuni. 70 d2g2ca1 not modelled 61.4 5 Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MogA-like 71 c3kydB_ not modelled 61.2 29 PDB header:ligase Chain: B: PDB Molecule:sumo-activating enzyme subunit 2; PDBTitle: human sumo e1~sumo1-amp tetrahedral intermediate mimic 72 d1ryba_ not modelled 60.7 23 Fold:Phosphorylase/hydrolase-like Superfamily:Peptidyl-tRNA hydrolase-like Family:Peptidyl-tRNA hydrolase-like 73 c2l18A_ not modelled 60.0 11 PDB header:oxidoreductase Chain: A: PDB Molecule:arsenate reductase; PDBTitle: an arsenate reductase in the phosphate binding state 74 c8ldhA_ not modelled 59.0 34 PDB header:oxidoreductase(choh(d)-nad(a)) Chain: A: PDB Molecule:m4 apo-lactate dehydrogenase; PDBTitle: refined crystal structure of dogfish m4 apo-lactate2 dehydrogenase 75 c2q1yB_ not modelled 58.9 30 PDB header:cell cycle, signaling protein Chain: B: PDB Molecule:cell division protein ftsz; PDBTitle: crystal structure of cell division protein ftsz from mycobacterium2 tuberculosis in complex with gtp-gamma-s 76 c2v6bB_ not modelled 58.7 28 PDB header:oxidoreductase Chain: B: PDB Molecule:l-lactate dehydrogenase; PDBTitle: crystal structure of lactate dehydrogenase from deinococcus2 radiodurans (apo form) 77 d1j5pa4 not modelled 58.6 50 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 78 c3g0oA_ not modelled 58.3 17 PDB header:oxidoreductase Chain: A: PDB Molecule:3-hydroxyisobutyrate dehydrogenase; PDBTitle: crystal structure of 3-hydroxyisobutyrate dehydrogenase2 (ygbj) from salmonella typhimurium 79 c3egoB_ not modelled 58.2 21 PDB header:oxidoreductase Chain: B: PDB Molecule:probable 2-dehydropantoate 2-reductase; PDBTitle: crystal structure of probable 2-dehydropantoate 2-reductase2 pane from bacillus subtilis 80 c1nhqA_ not modelled 54.9 26 PDB header:oxidoreductase (h2o2(a)) Chain: A: PDB Molecule:nadh peroxidase; PDBTitle: crystallographic analyses of nadh peroxidase cys42ala and cys42ser2 mutants: active site structure, mechanistic implications, and an3 unusual environment of arg303 81 d1yovb1 not modelled 54.9 24 Fold:Activating enzymes of the ubiquitin-like proteins Superfamily:Activating enzymes of the ubiquitin-like proteins Family:Ubiquitin activating enzymes (UBA) 82 d5pnta_ not modelled 54.1 20 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 83 c3prjB_ not modelled 54.0 21 PDB header:oxidoreductase Chain: B: PDB Molecule:udp-glucose 6-dehydrogenase; PDBTitle: role of packing defects in the evolution of allostery and induced fit2 in human udp-glucose dehydrogenase. 84 c2pjkA_ not modelled 53.9 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:178aa long hypothetical molybdenum cofactor PDBTitle: structure of hypothetical molybdenum cofactor biosynthesis2 protein b from sulfolobus tokodaii 85 c3h9gA_ not modelled 53.6 24 PDB header:transferase/antibiotic Chain: A: PDB Molecule:mccb protein; PDBTitle: crystal structure of e. coli mccb + mcca-n7isoasn 86 d1dg9a_ not modelled 52.3 23 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 87 d1ydga_ not modelled 51.9 16 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:WrbA-like 88 c3rofA_ not modelled 51.8 21 PDB header:hydrolase Chain: A: PDB Molecule:low molecular weight protein-tyrosine-phosphatase ptpa; PDBTitle: crystal structure of the s. aureus protein tyrosine phosphatase ptpa 89 d1nhpa1 not modelled 51.7 34 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 90 d1jaya_ not modelled 51.5 33 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 91 d1t2da1 not modelled 50.6 21 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:LDH N-terminal domain-like 92 d1sc6a2 not modelled 50.6 16 Fold:Flavodoxin-like Superfamily:Formate/glycerate dehydrogenase catalytic domain-like Family:Formate/glycerate dehydrogenases, substrate-binding domain 93 c1zggA_ not modelled 48.5 22 PDB header:hydrolase Chain: A: PDB Molecule:putative low molecular weight protein-tyrosine- PDBTitle: solution structure of a low molecular weight protein2 tyrosine phosphatase from bacillus subtilis 94 c3m2pD_ not modelled 47.9 17 PDB header:isomerase Chain: D: PDB Molecule:udp-n-acetylglucosamine 4-epimerase; PDBTitle: the crystal structure of udp-n-acetylglucosamine 4-epimerase2 from bacillus cereus 95 c2hunB_ not modelled 47.8 27 PDB header:lyase Chain: B: PDB Molecule:336aa long hypothetical dtdp-glucose 4,6-dehydratase; PDBTitle: crystal structure of hypothetical protein ph0414 from pyrococcus2 horikoshii ot3 96 d1i36a2 not modelled 47.5 20 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 97 d1vl0a_ not modelled 47.3 18 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 98 c3plnA_ not modelled 47.3 35 PDB header:oxidoreductase Chain: A: PDB Molecule:udp-glucose 6-dehydrogenase; PDBTitle: crystal structure of klebsiella pneumoniae udp-glucose 6-dehydrogenase2 complexed with udp-glucose 99 c1i36A_ not modelled 47.2 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein mth1747; PDBTitle: structure of conserved protein mth1747 of unknown function2 reveals structural similarity with 3-hydroxyacid3 dehydrogenases 100 d1a9xa3 not modelled 46.3 22 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 101 d1pjca1 not modelled 46.3 29 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Formate/glycerate dehydrogenases, NAD-domain 102 c2dc1A_ not modelled 46.2 41 PDB header:oxidoreductase Chain: A: PDB Molecule:l-aspartate dehydrogenase; PDBTitle: crystal structure of l-aspartate dehydrogenase from2 hyperthermophilic archaeon archaeoglobus fulgidus 103 c1d4fD_ not modelled 45.3 20 PDB header:hydrolase Chain: D: PDB Molecule:s-adenosylhomocysteine hydrolase; PDBTitle: crystal structure of recombinant rat-liver d244e mutant s-2 adenosylhomocysteine hydrolase 104 c2cukC_ not modelled 45.2 16 PDB header:oxidoreductase Chain: C: PDB Molecule:glycerate dehydrogenase/glyoxylate reductase; PDBTitle: crystal structure of tt0316 protein from thermus thermophilus hb8 105 c3bioB_ not modelled 45.2 39 PDB header:oxidoreductase Chain: B: PDB Molecule:oxidoreductase, gfo/idh/moca family; PDBTitle: crystal structure of oxidoreductase (gfo/idh/moca family member) from2 porphyromonas gingivalis w83 106 d1leha1 not modelled 44.7 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Aminoacid dehydrogenase-like, C-terminal domain 107 c2p5uC_ not modelled 44.4 55 PDB header:isomerase Chain: C: PDB Molecule:udp-glucose 4-epimerase; PDBTitle: crystal structure of thermus thermophilus hb8 udp-glucose 4-2 epimerase complex with nad 108 c1gv1D_ not modelled 44.1 31 PDB header:oxidoreductase Chain: D: PDB Molecule:malate dehydrogenase; PDBTitle: structural basis for thermophilic protein stability:2 structures of thermophilic and mesophilic malate3 dehydrogenases 109 d1d1qa_ not modelled 43.6 16 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 110 c3ju3A_ not modelled 42.5 13 PDB header:oxidoreductase Chain: A: PDB Molecule:probable 2-oxoacid ferredoxin oxidoreductase, alpha chain; PDBTitle: crystal structure of alpha chain of probable 2-oxoacid ferredoxin2 oxidoreductase from thermoplasma acidophilum 111 c3hn2A_ not modelled 42.4 27 PDB header:oxidoreductase Chain: A: PDB Molecule:2-dehydropantoate 2-reductase; PDBTitle: crystal structure of 2-dehydropantoate 2-reductase from geobacter2 metallireducens gs-15 112 d1y1la_ not modelled 41.9 18 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 113 c3f46A_ not modelled 41.7 23 PDB header:oxidoreductase Chain: A: PDB Molecule:5,10-methenyltetrahydromethanopterin hydrogenase; PDBTitle: the crystal structure of c176a mutated [fe]-hydrogenase (hmd)2 holoenzyme from methanocaldococcus jannaschii 114 c2o3jC_ not modelled 41.7 25 PDB header:oxidoreductase Chain: C: PDB Molecule:udp-glucose 6-dehydrogenase; PDBTitle: structure of caenorhabditis elegans udp-glucose dehydrogenase 115 c2qytA_ not modelled 41.6 32 PDB header:oxidoreductase Chain: A: PDB Molecule:2-dehydropantoate 2-reductase; PDBTitle: crystal structure of 2-dehydropantoate 2-reductase from porphyromonas2 gingivalis w83 116 d1iira_ not modelled 41.3 21 Fold:UDP-Glycosyltransferase/glycogen phosphorylase Superfamily:UDP-Glycosyltransferase/glycogen phosphorylase Family:Gtf glycosyltransferase 117 c2vhyB_ not modelled 41.1 27 PDB header:oxidoreductase Chain: B: PDB Molecule:alanine dehydrogenase; PDBTitle: crystal structure of apo l-alanine dehydrogenase from2 mycobacterium tuberculosis 118 c2ew2B_ not modelled 41.0 31 PDB header:oxidoreductase Chain: B: PDB Molecule:2-dehydropantoate 2-reductase, putative; PDBTitle: crystal structure of the putative 2-dehydropantoate 2-reductase from2 enterococcus faecalis 119 c2q3eH_ not modelled 40.7 21 PDB header:oxidoreductase Chain: H: PDB Molecule:udp-glucose 6-dehydrogenase; PDBTitle: structure of human udp-glucose dehydrogenase complexed with nadh and2 udp-glucose 120 d1jl3a_ not modelled 40.4 24 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0