PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3f46A_

Fold library id	PDB Header	Molecule	Title
c3f46A_	PDB header: oxidoreductase	Chain: A: PDB Molecule: 5,10-methenyltetrahydromethanopterin hydrogenase;	PDBTitle: the crystal structure of c176a mutated [fe]-hydrogenase2 (hmd) holoenzyme from methanocaldococcus jannaschii

Links to external resources
Added to library: Tue Mar 16 12:12:21 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence M K I A I L G A G C Y R T H A A A G I T N F M R A C E V A K E V G K P E I A L T H S S I T Y G A E L L H L V P D V K E V I V S D P C F A E E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T
G G G G G
T T
G G G G S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence P G L V V I D E F D P K E V M E A H L S G N P E S I M P K I R E V V K A K A K E L P K P P K A C I H L V H P E D V G L K V T S D D R E A V E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S
T T
G G G T T T S
T T T S S
G G G G T
S
T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence G A D I V I T W L P K G N K Q P D I I K K F A D A I P E G A I V T H A A T I P T T K F A K I F K D L G R E D L N I T S Y H P G C V P E M K G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S
S S S
T T G G G S
T T
T T S
T T
T T S
B
S S
T T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence Q V Y I A E G Y A S E E A V N K L Y E I G K I A R G K A F K M P A N L I G P V C D M C S A V T A T V Y A G L L A Y R D A V T K I L G A P A D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S
S
S T T T S

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . .

Sequence F A Q M M A D E A L T Q I H N L M K E K G I A N M E E A L D P A A L L G T A D S M C F G P L A E I L P T A L K V L E K H K V V E E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G G G G T S
G G G G T T T G G G G
S G G G T T T

Download: PDB structure FASTA sequence
Hidden Markov model

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	M	K	I	A	I	L	G	A	G	C	Y	R	T	H	A	A	A	G	I	T	N	F	M	R	A	C	E	V	A	K	E	V	G	K	P	E	I	A	L	T	H	S	S	I	T	Y	G	A	E	L	L	H	L	V	P	D	V	K	E	V	I	V	S	D	P	C	F	A	E	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											S																						T		G	G	G	G	G																T	T									G	G	G	G	S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	P	G	L	V	V	I	D	E	F	D	P	K	E	V	M	E	A	H	L	S	G	N	P	E	S	I	M	P	K	I	R	E	V	V	K	A	K	A	K	E	L	P	K	P	P	K	A	C	I	H	L	V	H	P	E	D	V	G	L	K	V	T	S	D	D	R	E	A	V	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S								S											T	T		G	G	G	T													T	T	S			T	T	T					S	S		G	G	G	G	T					S							T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	G	A	D	I	V	I	T	W	L	P	K	G	N	K	Q	P	D	I	I	K	K	F	A	D	A	I	P	E	G	A	I	V	T	H	A	A	T	I	P	T	T	K	F	A	K	I	F	K	D	L	G	R	E	D	L	N	I	T	S	Y	H	P	G	C	V	P	E	M	K	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T		S								S	S	S								T	T	G	G	G	S		T	T							T	T	S												T	T		T	T	S						B		S	S		T	T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	Q	V	Y	I	A	E	G	Y	A	S	E	E	A	V	N	K	L	Y	E	I	G	K	I	A	R	G	K	A	F	K	M	P	A	N	L	I	G	P	V	C	D	M	C	S	A	V	T	A	T	V	Y	A	G	L	L	A	Y	R	D	A	V	T	K	I	L	G	A	P	A	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							S	S	S																	S															S	T	T																					T	S
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.
Sequence	F	A	Q	M	M	A	D	E	A	L	T	Q	I	H	N	L	M	K	E	K	G	I	A	N	M	E	E	A	L	D	P	A	A	L	L	G	T	A	D	S	M	C	F	G	P	L	A	E	I	L	P	T	A	L	K	V	L	E	K	H	K	V	V	E	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																						G	G	G	G	G	G	T	S		G	G	G	G	T	T	T	G	G	G	G		S	G	G	G	T	T												T