Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	N	Y	Q	N	D	D	L	R	I	K	E	I	K	E	L	L	P	P	V	A	L	L	E	K	F	P	A	T	E	N	A	A	N	T	V	A	H	A	R	K	A	I	H	K	I	L	K	G	N	D	D	R	L	L	V	V	I	G	P
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?						?	?	?	?	?	?	?																														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		C	S	I	H	D	P	V	A	A	K	E	Y	A	T	R	L	L	A	L	R	E	E	L	K	D	E	L	E	I	V	M	R	V	Y	F	E	K	P	R	T	T	V	G	W	K	G	L	I	N	D	P	H	M	D	N	S	F	Q	I	N
Secondary structure
SS confidence
Disorder																																																						?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		D	G	L	R	I	A	R	K	L	L	L	D	I	N	D	S	G	L	P	A	A	G	E	F	L	D	M	I	T	P	Q	Y	L	A	D	L	M	S	W	G	A	I	G	A	R	T	T	E	S	Q	V	H	R	E	L	A	S	G	L	S
Secondary structure
SS confidence
Disorder																																																										?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		C	P	V	G	F	K	N	G	T	D	G	T	I	K	V	A	I	D	A	I	N	A	A	G	A	P	H	C	F	L	S	V	T	K	W	G	H	S	A	I	V	N	T	S	G	N	G	D	C	H	I	I	L	R	G	G	K	E	P	N
Secondary structure
SS confidence
Disorder																																																												?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		Y	S	A	K	H	V	A	E	V	K	E	G	L	N	K	A	G	L	P	A	Q	V	M	I	D	F	S	H	A	N	S	S	K	Q	F	K	K	Q	M	D	V	C	A	D	V	C	Q	Q	I	A	G	G	E	K	A	I	I	G	V	M
Secondary structure
SS confidence
Disorder		?															?	?	?													?	?	?	?																	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence		V	E	S	H	L	V	E	G	N	Q	S	L	E	S	G	E	P	L	A	Y	G	K	S	I	T	D	A	C	I	G	W	E	D	T	D	A	L	L	R	Q	L	A	N	A	V	K	A	R	R	G
Secondary structure
SS confidence
Disorder										?	?	?	?	?	?	?	?	?	?																													?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1n8f chain A Region: 8 - 350 Aligned: 343 Modelled: 343 Confidence: 100.0% Identity: 100% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I DAHP synthetase Phyre2 PDB 3tqk chain A Region: 9 - 350 Aligned: 340 Modelled: 342 Confidence: 100.0% Identity: 54% PDB header:transferase Chain: A: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: structure of phospho-2-dehydro-3-deoxyheptonate aldolase from2 francisella tularensis schu s4 Phyre2 PDB 1of8 chain A Region: 8 - 349 Aligned: 335 Modelled: 342 Confidence: 100.0% Identity: 58% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I DAHP synthetase Phyre2 PDB 1ofa chain B Region: 8 - 349 Aligned: 333 Modelled: 342 Confidence: 100.0% Identity: 59% PDB header:lyase Chain: B: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: crystal structure of the tyrosine-regulated2 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase3 from saccharomyces cerevisiae in complex with4 phosphoenolpyruvate and cobalt(ii) Phyre2 PDB 1vr6 chain A domain 1 Region: 7 - 348 Aligned: 282 Modelled: 291 Confidence: 100.0% Identity: 23% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I DAHP synthetase Phyre2 PDB 1vs1 chain B Region: 42 - 349 Aligned: 240 Modelled: 262 Confidence: 100.0% Identity: 25% PDB header:transferase Chain: B: PDB Molecule:3-deoxy-7-phosphoheptulonate synthase; PDBTitle: crystal structure of 3-deoxy-d-arabino-heptulosonate-7-2 phosphate synthase (dahp synthase) from aeropyrum pernix3 in complex with mn2+ and pep Phyre2 PDB 1zco chain A Region: 42 - 348 Aligned: 241 Modelled: 265 Confidence: 100.0% Identity: 25% PDB header:lyase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphoheptonate aldolase; PDBTitle: crystal structure of pyrococcus furiosus 3-deoxy-d-arabino-2 heptulosonate 7-phosphate synthase Phyre2 PDB 2a21 chain A domain 1 Region: 52 - 344 Aligned: 239 Modelled: 258 Confidence: 100.0% Identity: 20% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I DAHP synthetase Phyre2 PDB 3nvt chain A Region: 43 - 347 Aligned: 237 Modelled: 259 Confidence: 100.0% Identity: 27% PDB header:transferase/isomerase Chain: A: PDB Molecule:3-deoxy-d-arabino-heptulosonate 7-phosphate synthase; PDBTitle: 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7-2 phosphoheptulonate synthase/chorismate mutase (aroa) from listeria3 monocytogenes egd-e Phyre2 PDB 3stg chain A Region: 42 - 348 Aligned: 250 Modelled: 264 Confidence: 100.0% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase; PDBTitle: crystal structure of a58p, del(n59), and loop 7 truncated mutant of 3-2 deoxy-d-manno-octulosonate 8-phosphate synthase (kdo8ps) from3 neisseria meningitidis Phyre2 PDB 3fs2 chain A Region: 42 - 347 Aligned: 237 Modelled: 267 Confidence: 100.0% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate2 aldolase from bruciella melitensis at 1.85a resolution Phyre2 PDB 1d9e chain A Region: 42 - 349 Aligned: 252 Modelled: 276 Confidence: 100.0% Identity: 17% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I DAHP synthetase Phyre2 PDB 1o60 chain A Region: 42 - 349 Aligned: 254 Modelled: 276 Confidence: 100.0% Identity: 19% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I DAHP synthetase Phyre2 PDB 3t4c chain D Region: 42 - 347 Aligned: 244 Modelled: 268 Confidence: 100.0% Identity: 20% PDB header:transferase Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 1; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia ambifaria Phyre2 PDB 3sz8 chain D Region: 49 - 343 Aligned: 235 Modelled: 276 Confidence: 100.0% Identity: 16% PDB header:transferase Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 2; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia pseudomallei Phyre2 PDB 3pg8 chain B Region: 42 - 348 Aligned: 235 Modelled: 248 Confidence: 100.0% Identity: 26% PDB header:transferase Chain: B: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: truncated form of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase2 from thermotoga maritima Phyre2 PDB 2zdr chain A domain 2 Region: 42 - 347 Aligned: 242 Modelled: 250 Confidence: 99.5% Identity: 17% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: NeuB-like Phyre2 PDB 1vli chain A domain 2 Region: 43 - 347 Aligned: 238 Modelled: 262 Confidence: 99.2% Identity: 17% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: NeuB-like Phyre2 PDB 1xuz chain A Region: 43 - 347 Aligned: 240 Modelled: 254 Confidence: 98.8% Identity: 17% PDB header:biosynthetic protein Chain: A: PDB Molecule:polysialic acid capsule biosynthesis protein siac; PDBTitle: crystal structure analysis of sialic acid synthase (neub)from2 neisseria meningitidis, bound to mn2+, phosphoenolpyruvate, and n-3 acetyl mannosaminitol Phyre2 PDB 1vli chain A Region: 42 - 347 Aligned: 243 Modelled: 251 Confidence: 98.2% Identity: 16% PDB header:biosynthetic protein Chain: A: PDB Molecule:spore coat polysaccharide biosynthesis protein spse; PDBTitle: crystal structure of spore coat polysaccharide biosynthesis protein2 spse (bsu37870) from bacillus subtilis at 2.38 a resolution Phyre2 1 d1n8fa_ 2 c3tqkA_ 3 d1of8a_ 4 c1ofaB_ 5 d1vr6a1 6 c1vs1B_ 7 c1zcoA_ 8 d2a21a1 9 c3nvtA_ 10 c3stgA_ 11 c3fs2A_ 12 d1d9ea_ 13 d1o60a_ 14 c3t4cD_ 15 c3sz8D_ 16 c3pg8B_ 17 d2zdra2 18 d1vlia2 19 c1xuzA_ 20 c1vliA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1n8fa_ 100.0 100 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 2 c3tqkA_ 100.0 54 PDB header:transferase Chain: A: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: structure of phospho-2-dehydro-3-deoxyheptonate aldolase from2 francisella tularensis schu s4 3 d1of8a_ 100.0 58 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 4 c1ofaB_ 100.0 59 PDB header:lyase Chain: B: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: crystal structure of the tyrosine-regulated2 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase3 from saccharomyces cerevisiae in complex with4 phosphoenolpyruvate and cobalt(ii) 5 d1vr6a1 100.0 23 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 6 c1vs1B_ 100.0 25 PDB header:transferase Chain: B: PDB Molecule:3-deoxy-7-phosphoheptulonate synthase; PDBTitle: crystal structure of 3-deoxy-d-arabino-heptulosonate-7-2 phosphate synthase (dahp synthase) from aeropyrum pernix3 in complex with mn2+ and pep 7 c1zcoA_ 100.0 25 PDB header:lyase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphoheptonate aldolase; PDBTitle: crystal structure of pyrococcus furiosus 3-deoxy-d-arabino-2 heptulosonate 7-phosphate synthase 8 d2a21a1 100.0 20 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 9 c3nvtA_ 100.0 27 PDB header:transferase/isomerase Chain: A: PDB Molecule:3-deoxy-d-arabino-heptulosonate 7-phosphate synthase; PDBTitle: 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7-2 phosphoheptulonate synthase/chorismate mutase (aroa) from listeria3 monocytogenes egd-e 10 c3stgA_ 100.0 17 PDB header:transferase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase; PDBTitle: crystal structure of a58p, del(n59), and loop 7 truncated mutant of 3-2 deoxy-d-manno-octulosonate 8-phosphate synthase (kdo8ps) from3 neisseria meningitidis 11 c3fs2A_ 100.0 22 PDB header:transferase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate2 aldolase from bruciella melitensis at 1.85a resolution 12 d1d9ea_ 100.0 17 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 13 d1o60a_ 100.0 19 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 14 c3t4cD_ 100.0 20 PDB header:transferase Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 1; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia ambifaria 15 c3sz8D_ 100.0 16 PDB header:transferase Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 2; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia pseudomallei 16 c3pg8B_ 100.0 26 PDB header:transferase Chain: B: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: truncated form of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase2 from thermotoga maritima 17 d2zdra2 99.5 17 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:NeuB-like 18 d1vlia2 99.2 17 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:NeuB-like 19 c1xuzA_ 98.8 17 PDB header:biosynthetic protein Chain: A: PDB Molecule:polysialic acid capsule biosynthesis protein siac; PDBTitle: crystal structure analysis of sialic acid synthase (neub)from2 neisseria meningitidis, bound to mn2+, phosphoenolpyruvate, and n-3 acetyl mannosaminitol 20 c1vliA_ 98.2 16 PDB header:biosynthetic protein Chain: A: PDB Molecule:spore coat polysaccharide biosynthesis protein spse; PDBTitle: crystal structure of spore coat polysaccharide biosynthesis protein2 spse (bsu37870) from bacillus subtilis at 2.38 a resolution 21 c3g8rA_ not modelled 97.5 12 PDB header:biosynthetic protein Chain: A: PDB Molecule:probable spore coat polysaccharide biosynthesis protein e; PDBTitle: crystal structure of putative spore coat polysaccharide biosynthesis2 protein e from chromobacterium violaceum atcc 12472 22 d2b7oa1 not modelled 97.5 23 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class-II DAHP synthetase 23 d1ajza_ not modelled 94.4 16 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 24 d1ad1a_ not modelled 88.7 11 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 25 c3tr9A_ not modelled 85.1 20 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase; PDBTitle: structure of a dihydropteroate synthase (folp) in complex with pteroic2 acid from coxiella burnetii 26 c3eb2A_ not modelled 84.8 14 PDB header:lyase Chain: A: PDB Molecule:putative dihydrodipicolinate synthetase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 rhodopseudomonas palustris at 2.0a resolution 27 c2y5sA_ not modelled 82.3 22 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase; PDBTitle: crystal structure of burkholderia cenocepacia dihydropteroate2 synthase complexed with 7,8-dihydropteroate. 28 c3e5bB_ not modelled 81.4 25 PDB header:lyase Chain: B: PDB Molecule:isocitrate lyase; PDBTitle: 2.4 a crystal structure of isocitrate lyase from brucella2 melitensis 29 c2bmbA_ not modelled 79.5 15 PDB header:transferase Chain: A: PDB Molecule:folic acid synthesis protein fol1; PDBTitle: x-ray structure of the bifunctional 6-hydroxymethyl-7,8-2 dihydroxypterin pyrophosphokinase dihydropteroate synthase3 from saccharomyces cerevisiae 30 c2dzaA_ not modelled 74.0 16 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase; PDBTitle: crystal structure of dihydropteroate synthase from thermus2 thermophilus hb8 in complex with 4-aminobenzoate 31 d1tx2a_ not modelled 71.3 12 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 32 c1tx2A_ not modelled 71.3 12 PDB header:transferase Chain: A: PDB Molecule:dhps, dihydropteroate synthase; PDBTitle: dihydropteroate synthetase, with bound inhibitor manic, from bacillus2 anthracis 33 d1eyea_ not modelled 67.0 13 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 34 c2p2sA_ not modelled 64.5 20 PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of putative oxidoreductase (yp_050235.1) from2 erwinia carotovora atroseptica scri1043 at 1.25 a resolution 35 c2p90B_ not modelled 52.1 17 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hypothetical protein cgl1923; PDBTitle: the crystal structure of a protein of unknown function from2 corynebacterium glutamicum atcc 13032 36 c2ze5A_ not modelled 50.1 21 PDB header:transferase Chain: A: PDB Molecule:isopentenyl transferase; PDBTitle: crystal structure of adenosine phosphate-isopentenyltransferase 37 d2p62a1 not modelled 48.7 17 Fold:PH0156-like Superfamily:PH0156-like Family:PH0156-like 38 c3btuD_ not modelled 46.6 15 PDB header:transcription Chain: D: PDB Molecule:galactose/lactose metabolism regulatory protein PDBTitle: crystal structure of the super-repressor mutant of gal80p2 from saccharomyces cerevisiae; gal80(s2) [e351k] 39 d1ydwa1 not modelled 46.1 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 40 d2v3za1 not modelled 45.9 18 Fold:Ribonuclease H-like motif Superfamily:Creatinase/prolidase N-terminal domain Family:Creatinase/prolidase N-terminal domain 41 c3fhlC_ not modelled 45.7 24 PDB header:oxidoreductase Chain: C: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of a putative oxidoreductase from bacteroides2 fragilis nctc 9343 42 c3fa4D_ not modelled 45.7 20 PDB header:lyase Chain: D: PDB Molecule:2,3-dimethylmalate lyase; PDBTitle: crystal structure of 2,3-dimethylmalate lyase, a pep mutase/isocitrate2 lyase superfamily member, triclinic crystal form 43 c2e3zB_ not modelled 44.6 20 PDB header:hydrolase Chain: B: PDB Molecule:beta-glucosidase; PDBTitle: crystal structure of intracellular family 1 beta-2 glucosidase bgl1a from the basidiomycete phanerochaete3 chrysosporium in substrate-free form 44 c3d3qB_ not modelled 43.2 23 PDB header:transferase Chain: B: PDB Molecule:trna delta(2)-isopentenylpyrophosphate PDBTitle: crystal structure of trna delta(2)-isopentenylpyrophosphate2 transferase (se0981) from staphylococcus epidermidis.3 northeast structural genomics consortium target ser100 45 c3oqbF_ not modelled 41.4 20 PDB header:oxidoreductase Chain: F: PDB Molecule:oxidoreductase; PDBTitle: crystal structure of putative oxidoreductase from bradyrhizobium2 japonicum usda 110 46 d1o5ka_ not modelled 40.9 17 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 47 d1u1ia1 not modelled 40.3 16 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 48 c1ofgF_ not modelled 38.1 22 PDB header:oxidoreductase Chain: F: PDB Molecule:glucose-fructose oxidoreductase; PDBTitle: glucose-fructose oxidoreductase 49 c1h6dL_ not modelled 38.1 22 PDB header:protein translocation Chain: L: PDB Molecule:precursor form of glucose-fructose PDBTitle: oxidized precursor form of glucose-fructose oxidoreductase2 from zymomonas mobilis complexed with glycerol 50 c1zlpA_ not modelled 37.5 19 PDB header:lyase Chain: A: PDB Molecule:petal death protein; PDBTitle: petal death protein psr132 with cysteine-linked glutaraldehyde forming2 a thiohemiacetal adduct 51 c2ixaA_ not modelled 36.7 17 PDB header:hydrolase Chain: A: PDB Molecule:alpha-n-acetylgalactosaminidase; PDBTitle: a-zyme, n-acetylgalactosaminidase 52 c3si9B_ not modelled 35.4 22 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from bartonella2 henselae 53 c3euwB_ not modelled 35.3 22 PDB header:oxidoreductase Chain: B: PDB Molecule:myo-inositol dehydrogenase; PDBTitle: crystal structure of a myo-inositol dehydrogenase from corynebacterium2 glutamicum atcc 13032 54 c3a8tA_ not modelled 35.3 19 PDB header:transferase Chain: A: PDB Molecule:adenylate isopentenyltransferase; PDBTitle: plant adenylate isopentenyltransferase in complex with atp 55 c3e35A_ not modelled 34.7 18 PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein sco1997; PDBTitle: actinobacteria-specific protein of unknown function, sco1997 56 c3ptkB_ not modelled 34.6 16 PDB header:hydrolase Chain: B: PDB Molecule:beta-glucosidase os4bglu12; PDBTitle: the crystal structure of rice (oryza sativa l.) os4bglu12 57 d1f74a_ not modelled 31.8 11 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 58 c2vqqA_ not modelled 31.8 17 PDB header:hydrolase Chain: A: PDB Molecule:histone deacetylase 4; PDBTitle: structure of hdac4 catalytic domain (a double cysteine-to-2 alanine mutant) bound to a trifluoromethylketone inhbitor 59 d1pffa_ not modelled 30.8 20 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:Cystathionine synthase-like 60 d2v89a1 not modelled 30.4 21 Fold:FYVE/PHD zinc finger Superfamily:FYVE/PHD zinc finger Family:PHD domain 61 c2qw5B_ not modelled 30.3 17 PDB header:isomerase Chain: B: PDB Molecule:xylose isomerase-like tim barrel; PDBTitle: crystal structure of a putative sugar phosphate isomerase/epimerase2 (ava4194) from anabaena variabilis atcc 29413 at 1.78 a resolution 62 c3h5dD_ not modelled 30.1 15 PDB header:lyase Chain: D: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: dihydrodipicolinate synthase from drug-resistant streptococcus2 pneumoniae 63 c3cprB_ not modelled 29.4 17 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthetase; PDBTitle: the crystal structure of corynebacterium glutamicum2 dihydrodipicolinate synthase to 2.2 a resolution 64 d2auwa1 not modelled 29.3 75 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:NE0471 C-terminal domain-like 65 c3dtyA_ not modelled 29.2 19 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase, gfo/idh/moca family; PDBTitle: crystal structure of an oxidoreductase from pseudomonas2 syringae 66 c3oixA_ not modelled 29.1 18 PDB header:oxidoreductase Chain: A: PDB Molecule:putative dihydroorotate dehydrogenase; dihydroorotate PDBTitle: crystal structure of the putative dihydroorotate dehydrogenase from2 streptococcus mutans 67 d1auaa2 not modelled 28.7 13 Fold:SpoIIaa-like Superfamily:CRAL/TRIO domain Family:CRAL/TRIO domain 68 c3na8A_ not modelled 28.3 13 PDB header:lyase Chain: A: PDB Molecule:putative dihydrodipicolinate synthetase; PDBTitle: crystal structure of a putative dihydrodipicolinate synthetase from2 pseudomonas aeruginosa 69 c3q2kB_ not modelled 28.3 16 PDB header:oxidoreductase Chain: B: PDB Molecule:oxidoreductase; PDBTitle: crystal structure of the wlba dehydrogenase from bordetella pertussis2 in complex with nadh and udp-glcnaca 70 d1ryda1 not modelled 28.0 20 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 71 d1sq5a_ not modelled 28.0 17 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Phosphoribulokinase/pantothenate kinase 72 c3kuxA_ not modelled 27.3 29 PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: structure of the ypo2259 putative oxidoreductase from yersinia pestis 73 c2wamB_ not modelled 27.2 17 PDB header:unknown function Chain: B: PDB Molecule:conserved hypothetical alanine and leucine rich PDBTitle: crystal structure of mycobacterium tuberculosis unknown2 function protein rv2714 74 c2hjpA_ not modelled 27.2 17 PDB header:hydrolase Chain: A: PDB Molecule:phosphonopyruvate hydrolase; PDBTitle: crystal structure of phosphonopyruvate hydrolase complex with2 phosphonopyruvate and mg++ 75 c2bdqA_ not modelled 26.6 20 PDB header:metal transport Chain: A: PDB Molecule:copper homeostasis protein cutc; PDBTitle: crystal structure of the putative copper homeostasis2 protein cutc from streptococcus agalactiae, northeast3 strucural genomics target sar15. 76 c3exaD_ not modelled 26.3 24 PDB header:transferase Chain: D: PDB Molecule:trna delta(2)-isopentenylpyrophosphate PDBTitle: crystal structure of the full-length trna2 isopentenylpyrophosphate transferase (bh2366) from3 bacillus halodurans, northeast structural genomics4 consortium target bhr41. 77 c2auwB_ not modelled 26.1 75 PDB header:unknown function Chain: B: PDB Molecule:hypothetical protein ne0471; PDBTitle: crystal structure of putative dna binding protein ne0471 from2 nitrosomonas europaea atcc 19718 78 c3c1aB_ not modelled 25.9 23 PDB header:oxidoreductase Chain: B: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of a putative oxidoreductase (zp_00056571.1) from2 magnetospirillum magnetotacticum ms-1 at 1.85 a resolution 79 d1ulza3 not modelled 25.9 12 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 80 c3moiA_ not modelled 25.2 18 PDB header:oxidoreductase Chain: A: PDB Molecule:probable dehydrogenase; PDBTitle: the crystal structure of the putative dehydrogenase from bordetella2 bronchiseptica rb50 81 c3noeA_ not modelled 24.9 17 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from pseudomonas2 aeruginosa 82 c3f4lF_ not modelled 24.5 29 PDB header:oxidoreductase Chain: F: PDB Molecule:putative oxidoreductase yhhx; PDBTitle: crystal structure of a probable oxidoreductase yhhx in2 triclinic form. northeast structural genomics target er647 83 d1t6ua_ not modelled 24.1 30 Fold:Four-helical up-and-down bundle Superfamily:Nickel-containing superoxide dismutase, NiSOD Family:Nickel-containing superoxide dismutase, NiSOD 84 d1olma3 not modelled 24.0 11 Fold:SpoIIaa-like Superfamily:CRAL/TRIO domain Family:CRAL/TRIO domain 85 c3fd8A_ not modelled 23.7 22 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase, gfo/idh/moca family; PDBTitle: crystal structure of an oxidoreductase from enterococcus2 faecalis 86 c3ahyD_ not modelled 23.5 17 PDB header:hydrolase Chain: D: PDB Molecule:beta-glucosidase; PDBTitle: crystal structure of beta-glucosidase 2 from fungus trichoderma reesei2 in complex with tris 87 c3e18A_ not modelled 22.8 19 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase; PDBTitle: crystal structure of nad-binding protein from listeria innocua 88 d1w79a1 not modelled 22.4 21 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:Dac-like 89 c3db2C_ not modelled 22.2 20 PDB header:oxidoreductase Chain: C: PDB Molecule:putative nadph-dependent oxidoreductase; PDBTitle: crystal structure of a putative nadph-dependent oxidoreductase2 (dhaf_2064) from desulfitobacterium hafniense dcb-2 at 1.70 a3 resolution 90 d1igwa_ not modelled 22.1 24 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 91 c3crqA_ not modelled 22.1 20 PDB header:transferase Chain: A: PDB Molecule:trna delta(2)-isopentenylpyrophosphate PDBTitle: structure of trna dimethylallyltransferase: rna2 modification through a channel 92 d2ex2a1 not modelled 22.1 23 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:Dac-like 93 d1n8pa_ not modelled 21.5 45 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:Cystathionine synthase-like 94 c2nmpC_ not modelled 21.3 45 PDB header:lyase Chain: C: PDB Molecule:cystathionine gamma-lyase; PDBTitle: crystal structure of human cystathionine gamma lyase 95 c1f9cA_ not modelled 21.3 16 PDB header:isomerase Chain: A: PDB Molecule:protein (muconate cycloisomerase i); PDBTitle: crystal structure of mle d178n variant 96 c3m2tA_ not modelled 20.9 21 PDB header:oxidoreductase Chain: A: PDB Molecule:probable dehydrogenase; PDBTitle: the crystal structure of dehydrogenase from chromobacterium2 violaceum 97 c3e82A_ not modelled 20.7 26 PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of a putative oxidoreductase from2 klebsiella pneumoniae 98 c3daqB_ not modelled 20.7 20 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from methicillin-2 resistant staphylococcus aureus 99 d1qgna_ not modelled 20.6 30 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:Cystathionine synthase-like 100 c1zh8B_ not modelled 20.5 20 PDB header:oxidoreductase Chain: B: PDB Molecule:oxidoreductase; PDBTitle: crystal structure of oxidoreductase (tm0312) from thermotoga maritima2 at 2.50 a resolution 101 c3fozB_ not modelled 20.5 26 PDB header:transferase/rna Chain: B: PDB Molecule:trna delta(2)-isopentenylpyrophosphate transferase; PDBTitle: structure of e. coli isopentenyl-trna transferase in complex with e.2 coli trna(phe) 102 c2jf7B_ not modelled 20.4 16 PDB header:hydrolase Chain: B: PDB Molecule:strictosidine-o-beta-d-glucosidase; PDBTitle: structure of strictosidine glucosidase

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0