Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	I	I	R	D	E	N	Y	F	T	D	K	Y	E	L	T	R	T	H	S	E	V	L	E	A	V	K	V	V	K	P	G	K	T	L	D	L	G	C	G	N	G	R	N	S	L	Y	L	A	A	N	G	Y	D	V	D	A	W	D	K
Secondary structure
SS confidence
Disorder		?	?	?	?	?		?				?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		N	A	M	S	I	A	N	V	E	R	I	K	S	I	E	N	L	D	N	L	H	T	R	V	V	D	L	N	N	L	T	F	D	R	Q	Y	D	F	I	L	S	T	V	V	L	M	F	L	E	A	K	T	I	P	G	L	I	A	N	M
Secondary structure
SS confidence
Disorder															?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		Q	R	C	T	K	P	G	G	Y	N	L	I	V	A	A	M	D	T	A	D	Y	P	C	T	V	G	F	P	F	A	F	K	E	G	E	L	R	R	Y	Y	E	G	W	E	R	V	K	Y	N	E	D	V	G	E	L	H	R	T	D	A
Secondary structure
SS confidence
Disorder																			?	?	?	?	?	?	?																																			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.
Sequence		N	G	N	R	I	K	L	R	F	A	T	M	L	A	R	K	K
Secondary structure
SS confidence
Disorder		?	?														?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3m70 chain A Region: 3 - 197 Aligned: 194 Modelled: 194 Confidence: 100.0% Identity: 53% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:tellurite resistance protein tehb homolog; PDBTitle: crystal structure of tehb from haemophilus influenzae Phyre2 PDB 2i6g chain A domain 1 Region: 1 - 196 Aligned: 167 Modelled: 181 Confidence: 100.0% Identity: 69% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: TehB-like Phyre2 PDB 3lcc chain A Region: 5 - 188 Aligned: 181 Modelled: 184 Confidence: 99.9% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:putative methyl chloride transferase; PDBTitle: structure of a sam-dependent halide methyltransferase from arabidopsis2 thaliana Phyre2 PDB 2bzg chain A domain 1 Region: 5 - 197 Aligned: 191 Modelled: 193 Confidence: 99.9% Identity: 14% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: Thiopurine S-methyltransferase Phyre2 PDB 3bgd chain B Region: 5 - 197 Aligned: 191 Modelled: 193 Confidence: 99.9% Identity: 15% PDB header:transferase Chain: B: PDB Molecule:thiopurine s-methyltransferase; PDBTitle: thiopurine s-methyltransferase Phyre2 PDB 3e23 chain A Region: 7 - 196 Aligned: 177 Modelled: 188 Confidence: 99.9% Identity: 22% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein rpa2492; PDBTitle: crystal structure of the rpa2492 protein in complex with2 sam from rhodopseudomonas palustris, northeast structural3 genomics consortium target rpr299 Phyre2 PDB 3mer chain A Region: 18 - 196 Aligned: 166 Modelled: 179 Confidence: 99.9% Identity: 19% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:slr1183 protein; PDBTitle: crystal structure of the methyltransferase slr1183 from2 synechocystis sp. pcc 6803, northeast structural genomics3 consortium target sgr145 Phyre2 PDB 1pjz chain A Region: 21 - 170 Aligned: 148 Modelled: 150 Confidence: 99.9% Identity: 14% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: Thiopurine S-methyltransferase Phyre2 PDB 3h2b chain B Region: 6 - 196 Aligned: 174 Modelled: 177 Confidence: 99.9% Identity: 16% PDB header:transferase Chain: B: PDB Molecule:sam-dependent methyltransferase; PDBTitle: crystal structure of the sam-dependent methyltransferase2 cg3271 from corynebacterium glutamicum in complex with s-3 adenosyl-l-homocysteine and pyrophosphate. northeast4 structural genomics consortium target cgr113a Phyre2 PDB 2ex4 chain A domain 1 Region: 22 - 170 Aligned: 149 Modelled: 149 Confidence: 99.9% Identity: 18% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: AD-003 protein-like Phyre2 PDB 3ofk chain A Region: 6 - 134 Aligned: 127 Modelled: 129 Confidence: 99.9% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:nodulation protein s; PDBTitle: crystal structure of n-methyltransferase nods from bradyrhizobium2 japonicum wm9 in complex with s-adenosyl-l-homocysteine (sah) Phyre2 PDB 1ve3 chain A domain 1 Region: 20 - 135 Aligned: 116 Modelled: 116 Confidence: 99.9% Identity: 20% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: CAC2371-like Phyre2 PDB 2a14 chain A domain 1 Region: 27 - 197 Aligned: 167 Modelled: 171 Confidence: 99.9% Identity: 17% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: Arylamine N-methyltransferase Phyre2 PDB 1xtp chain A Region: 20 - 169 Aligned: 149 Modelled: 150 Confidence: 99.9% Identity: 14% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: AD-003 protein-like Phyre2 PDB 3ujc chain A Region: 4 - 144 Aligned: 140 Modelled: 141 Confidence: 99.9% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:phosphoethanolamine n-methyltransferase; PDBTitle: phosphoethanolamine methyltransferase mutant (h132a) from plasmodium2 falciparum in complex with phosphocholine Phyre2 PDB 3g5l chain A Region: 17 - 197 Aligned: 177 Modelled: 181 Confidence: 99.9% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:putative s-adenosylmethionine dependent PDBTitle: crystal structure of putative s-adenosylmethionine2 dependent methyltransferase from listeria monocytogenes Phyre2 PDB 3e8s chain A Region: 4 - 197 Aligned: 182 Modelled: 194 Confidence: 99.9% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:putative sam dependent methyltransferase; PDBTitle: crystal structure of putative sam dependent methyltransferase in2 complex with sah (np_744700.1) from pseudomonas putida kt2440 at 2.103 a resolution Phyre2 PDB 1vl5 chain B Region: 16 - 140 Aligned: 123 Modelled: 125 Confidence: 99.9% Identity: 14% PDB header:transferase Chain: B: PDB Molecule:unknown conserved protein bh2331; PDBTitle: crystal structure of a putative methyltransferase (bh2331) from2 bacillus halodurans c-125 at 1.95 a resolution Phyre2 PDB 1vl5 chain A Region: 16 - 140 Aligned: 123 Modelled: 125 Confidence: 99.9% Identity: 14% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: UbiE/COQ5-like Phyre2 PDB 2yr0 chain A Region: 20 - 135 Aligned: 114 Modelled: 113 Confidence: 99.9% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:hypothetical protein ttha0223; PDBTitle: crystal structure of hypothetical methyltransferase ttha0223 from2 thermus thermophilus hb8 Phyre2 1 c3m70A_ 2 d2i6ga1 3 c3lccA_ 4 d2bzga1 5 c3bgdB_ 6 c3e23A_ 7 c3merA_ 8 d1pjza_ 9 c3h2bB_ 10 d2ex4a1 11 c3ofkA_ 12 d1ve3a1 13 d2a14a1 14 d1xtpa_ 15 c3ujcA_ 16 c3g5lA_ 17 c3e8sA_ 18 c1vl5B_ 19 d1vl5a_ 20 c2yr0A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499