Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP77245
DateThu Jan 5 12:26:46 GMT 2012
Unique Job ID49e70d8001fb5d57

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3shoA_
Top template information
PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional regulator, rpir family;
PDBTitle: crystal structure of rpir transcription factor from sphaerobacter2 thermophilus (sugar isomerase domain)
Confidence and coverage
Confidence: 99.9% Coverage: 64%
182 residues ( 64% of your sequence) have been modelled with 99.9% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
276 residues ( 97%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MLYLTKISNAGSEFTENEQKIADFLQANVSELQSVSSRQMAKQLGISQSSIVKFAQKLGA
Secondary structure 












SS confidence 



























































Disorder  ??







?????



























?















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   .........70.........80.........90.........100.........110.........120
Sequence  QGFTELRMALIGEYSASREKTNATALHLHSSITSDDSLEVIARKLNREKELALEQTCALL
Secondary structure 

















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Disorder 















???????????????????
?






















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   .........130.........140.........150.........160.........170.........180
Sequence  DYARLQKIIEVISKAPFIQITGLGGSALVGRDLSFKLMKIGYRVACEADTHVQATVSQAL
Secondary structure 













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   .........190.........200.........210.........220.........230.........240
Sequence  KKGDVQIAISYSGSKKEIVLCAEAARKQGATVIAITSLTDSPLRRLAHFTLDTVSGETEW
Secondary structure 

























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Disorder 






































?















??
?
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   .........250.........260.........270.........280.....
Sequence  RSSSMSTRTAQNSVTDLLFVGLVQLNDVESLKMIQRSSELTQRLK
Secondary structure 






SS confidence 












































Disorder  ??
?






































??
Disorder confidence 












































 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3sho chain A

3D model

Region: 97 - 283
Aligned: 182
Modelled: 187
Confidence: 99.9%
Identity: 19%
PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional regulator, rpir family;
PDBTitle: crystal structure of rpir transcription factor from sphaerobacter2 thermophilus (sugar isomerase domain)

Phyre2

PDB 3fxa chain A

3D model

Region: 94 - 277
Aligned: 184
Modelled: 184
Confidence: 99.9%
Identity: 17%
PDB header:sugar binding protein
Chain: A: PDB Molecule:sis domain protein;
PDBTitle: crystal structure of a putative sugar-phosphate isomerase2 (lmof2365_0531) from listeria monocytogenes str. 4b f2365 at 1.60 a3 resolution

Phyre2

PDB 2xhz chain C

3D model

Region: 97 - 267
Aligned: 171
Modelled: 171
Confidence: 99.9%
Identity: 19%
PDB header:isomerase
Chain: C: PDB Molecule:arabinose 5-phosphate isomerase;
PDBTitle: probing the active site of the sugar isomerase domain from e. coli2 arabinose-5-phosphate isomerase via x-ray crystallography

Phyre2

PDB 3etn chain D

3D model

Region: 96 - 277
Aligned: 182
Modelled: 182
Confidence: 99.9%
Identity: 19%
PDB header:isomerase
Chain: D: PDB Molecule:putative phosphosugar isomerase involved in capsule
PDBTitle: crystal structure of putative phosphosugar isomerase involved in2 capsule formation (yp_209877.1) from bacteroides fragilis nctc 93433 at 1.70 a resolution

Phyre2

PDB 1vim chain A

3D model

Region: 96 - 277
Aligned: 177
Modelled: 182
Confidence: 99.9%
Identity: 19%
Fold: SIS domain
Superfamily: SIS domain
Family: mono-SIS domain

Phyre2

PDB 1m3s chain A

3D model

Region: 103 - 280
Aligned: 173
Modelled: 178
Confidence: 99.9%
Identity: 18%
Fold: SIS domain
Superfamily: SIS domain
Family: mono-SIS domain

Phyre2

PDB 1jeo chain A

3D model

Region: 104 - 277
Aligned: 166
Modelled: 174
Confidence: 99.9%
Identity: 22%
Fold: SIS domain
Superfamily: SIS domain
Family: mono-SIS domain

Phyre2

PDB 2puw chain A

3D model

Region: 98 - 284
Aligned: 186
Modelled: 187
Confidence: 99.8%
Identity: 13%
PDB header:transferase
Chain: A: PDB Molecule:isomerase domain of glutamine-fructose-6-phosphate
PDBTitle: the crystal structure of isomerase domain of glucosamine-6-phosphate2 synthase from candida albicans

Phyre2

PDB 3trj chain C

3D model

Region: 96 - 265
Aligned: 163
Modelled: 170
Confidence: 99.8%
Identity: 18%
PDB header:isomerase
Chain: C: PDB Molecule:phosphoheptose isomerase;
PDBTitle: structure of a phosphoheptose isomerase from francisella tularensis

Phyre2

PDB 2zj3 chain A

3D model

Region: 98 - 283
Aligned: 185
Modelled: 185
Confidence: 99.8%
Identity: 14%
PDB header:transferase
Chain: A: PDB Molecule:glucosamine--fructose-6-phosphate
PDBTitle: isomerase domain of human glucose:fructose-6-phosphate2 amidotransferase

Phyre2

PDB 1x92 chain A

3D model

Region: 97 - 265
Aligned: 163
Modelled: 169
Confidence: 99.8%
Identity: 20%
Fold: SIS domain
Superfamily: SIS domain
Family: mono-SIS domain

Phyre2

PDB 1j5x chain A

3D model

Region: 108 - 283
Aligned: 174
Modelled: 176
Confidence: 99.8%
Identity: 13%
Fold: SIS domain
Superfamily: SIS domain
Family: double-SIS domain

Phyre2

PDB 1tk9 chain A

3D model

Region: 96 - 262
Aligned: 161
Modelled: 166
Confidence: 99.8%
Identity: 19%
Fold: SIS domain
Superfamily: SIS domain
Family: mono-SIS domain

Phyre2

PDB 2yva chain B

3D model

Region: 98 - 265
Aligned: 160
Modelled: 168
Confidence: 99.8%
Identity: 19%
PDB header:dna binding protein
Chain: B: PDB Molecule:dnaa initiator-associating protein diaa;
PDBTitle: crystal structure of escherichia coli diaa

Phyre2

PDB 1nri chain A

3D model

Region: 77 - 268
Aligned: 187
Modelled: 192
Confidence: 99.8%
Identity: 21%
Fold: SIS domain
Superfamily: SIS domain
Family: mono-SIS domain

Phyre2

PDB 1nri chain A

3D model

Region: 77 - 268
Aligned: 187
Modelled: 192
Confidence: 99.8%
Identity: 21%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein hi0754;
PDBTitle: crystal structure of putative phosphosugar isomerase hi0754 from2 haemophilus influenzae

Phyre2

PDB 2a3n chain A

3D model

Region: 107 - 283
Aligned: 171
Modelled: 177
Confidence: 99.8%
Identity: 19%
PDB header:sugar binding protein
Chain: A: PDB Molecule:putative glucosamine-fructose-6-phosphate aminotransferase;
PDBTitle: crystal structure of a putative glucosamine-fructose-6-phosphate2 aminotransferase (stm4540.s) from salmonella typhimurium lt2 at 1.353 a resolution

Phyre2

PDB 1x94 chain A

3D model

Region: 95 - 265
Aligned: 166
Modelled: 171
Confidence: 99.8%
Identity: 16%
Fold: SIS domain
Superfamily: SIS domain
Family: mono-SIS domain

Phyre2

PDB 3fj1 chain A

3D model

Region: 106 - 283
Aligned: 175
Modelled: 178
Confidence: 99.7%
Identity: 18%
PDB header:isomerase
Chain: A: PDB Molecule:putative phosphosugar isomerase;
PDBTitle: crystal structure of putative phosphosugar isomerase (yp_167080.1)2 from silicibacter pomeroyi dss-3 at 1.75 a resolution

Phyre2

PDB 2x3y chain A

3D model

Region: 93 - 265
Aligned: 167
Modelled: 173
Confidence: 99.7%
Identity: 17%
PDB header:isomerase
Chain: A: PDB Molecule:phosphoheptose isomerase;
PDBTitle: crystal structure of gmha from burkholderia pseudomallei

Phyre2

PDB 3iwf chain A

3D model

Region: 2 - 88
Aligned: 87
Modelled: 86
Confidence: 99.7%
Identity: 30%
PDB header:transcription regulator
Chain: A: PDB Molecule:transcription regulator rpir family;
PDBTitle: the crystal structure of the n-terminal domain of a rpir2 transcriptional regulator from staphylococcus epidermidis to 1.4a

Phyre2
1

c3shoA_
2

c3fxaA_
3

c2xhzC_
4

c3etnD_
5

d1vima_
6

d1m3sa_
7

d1jeoa_
8

c2puwA_
9

c3trjC_
10

c2zj3A_
11

d1x92a_
12

d1j5xa_
13

d1tk9a_
14

c2yvaB_
15

d1nria_
16

c1nriA_
17

c2a3nA_
18

d1x94a_
19

c3fj1A_
20

c2x3yA_
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c3iwfA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3shoA_



99.9 19 PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional regulator, rpir family;
PDBTitle: crystal structure of rpir transcription factor from sphaerobacter2 thermophilus (sugar isomerase domain)
2c3fxaA_



99.9 17 PDB header:sugar binding protein
Chain: A: PDB Molecule:sis domain protein;
PDBTitle: crystal structure of a putative sugar-phosphate isomerase2 (lmof2365_0531) from listeria monocytogenes str. 4b f2365 at 1.60 a3 resolution
3c2xhzC_



99.9 19 PDB header:isomerase
Chain: C: PDB Molecule:arabinose 5-phosphate isomerase;
PDBTitle: probing the active site of the sugar isomerase domain from e. coli2 arabinose-5-phosphate isomerase via x-ray crystallography
4c3etnD_



99.9 19 PDB header:isomerase
Chain: D: PDB Molecule:putative phosphosugar isomerase involved in capsule
PDBTitle: crystal structure of putative phosphosugar isomerase involved in2 capsule formation (yp_209877.1) from bacteroides fragilis nctc 93433 at 1.70 a resolution
5d1vima_



99.9 19 Fold:SIS domain
Superfamily:SIS domain
Family:mono-SIS domain
6d1m3sa_



99.9 18 Fold:SIS domain
Superfamily:SIS domain
Family:mono-SIS domain
7d1jeoa_



99.9 22 Fold:SIS domain
Superfamily:SIS domain
Family:mono-SIS domain
8c2puwA_



99.8 13 PDB header:transferase
Chain: A: PDB Molecule:isomerase domain of glutamine-fructose-6-phosphate
PDBTitle: the crystal structure of isomerase domain of glucosamine-6-phosphate2 synthase from candida albicans
9c3trjC_



99.8 18 PDB header:isomerase
Chain: C: PDB Molecule:phosphoheptose isomerase;
PDBTitle: structure of a phosphoheptose isomerase from francisella tularensis
10c2zj3A_



99.8 14 PDB header:transferase
Chain: A: PDB Molecule:glucosamine--fructose-6-phosphate
PDBTitle: isomerase domain of human glucose:fructose-6-phosphate2 amidotransferase
11d1x92a_



99.8 20 Fold:SIS domain
Superfamily:SIS domain
Family:mono-SIS domain
12d1j5xa_



99.8 13 Fold:SIS domain
Superfamily:SIS domain
Family:double-SIS domain
13d1tk9a_



99.8 19 Fold:SIS domain
Superfamily:SIS domain
Family:mono-SIS domain
14c2yvaB_



99.8 19 PDB header:dna binding protein
Chain: B: PDB Molecule:dnaa initiator-associating protein diaa;
PDBTitle: crystal structure of escherichia coli diaa
15d1nria_



99.8 21 Fold:SIS domain
Superfamily:SIS domain
Family:mono-SIS domain
16c1nriA_



99.8 21 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein hi0754;
PDBTitle: crystal structure of putative phosphosugar isomerase hi0754 from2 haemophilus influenzae
17c2a3nA_



99.8 19 PDB header:sugar binding protein
Chain: A: PDB Molecule:putative glucosamine-fructose-6-phosphate aminotransferase;
PDBTitle: crystal structure of a putative glucosamine-fructose-6-phosphate2 aminotransferase (stm4540.s) from salmonella typhimurium lt2 at 1.353 a resolution
18d1x94a_



99.8 16 Fold:SIS domain
Superfamily:SIS domain
Family:mono-SIS domain
19c3fj1A_



99.7 18 PDB header:isomerase
Chain: A: PDB Molecule:putative phosphosugar isomerase;
PDBTitle: crystal structure of putative phosphosugar isomerase (yp_167080.1)2 from silicibacter pomeroyi dss-3 at 1.75 a resolution
20c2x3yA_



99.7 17 PDB header:isomerase
Chain: A: PDB Molecule:phosphoheptose isomerase;
PDBTitle: crystal structure of gmha from burkholderia pseudomallei
21c3euaD_



not modelled 99.7 17 PDB header:isomerase
Chain: D: PDB Molecule:putative fructose-aminoacid-6-phosphate deglycase;
PDBTitle: crystal structure of a putative phosphosugar isomerase (bsu32610) from2 bacillus subtilis at 1.90 a resolution
22c3hbaA_



not modelled 99.7 17 PDB header:isomerase
Chain: A: PDB Molecule:putative phosphosugar isomerase;
PDBTitle: crystal structure of a putative phosphosugar isomerase (sden_2705)2 from shewanella denitrificans os217 at 2.00 a resolution
23c3cvjB_



not modelled 99.7 19 PDB header:isomerase
Chain: B: PDB Molecule:putative phosphoheptose isomerase;
PDBTitle: crystal structure of a putative phosphoheptose isomerase (bh3325) from2 bacillus halodurans c-125 at 2.00 a resolution
24c3iwfA_



99.7 30 PDB header:transcription regulator
Chain: A: PDB Molecule:transcription regulator rpir family;
PDBTitle: the crystal structure of the n-terminal domain of a rpir2 transcriptional regulator from staphylococcus epidermidis to 1.4a
25c3g68A_



not modelled 99.7 12 PDB header:isomerase
Chain: A: PDB Molecule:putative phosphosugar isomerase;
PDBTitle: crystal structure of a putative phosphosugar isomerase (cd3275) from2 clostridium difficile 630 at 1.80 a resolution
26c3tbfA_



not modelled 99.7 18 PDB header:transferase
Chain: A: PDB Molecule:glucosamine--fructose-6-phosphate aminotransferase
PDBTitle: c-terminal domain of glucosamine-fructose-6-phosphate aminotransferase2 from francisella tularensis.
27d1moqa_



not modelled 99.7 19 Fold:SIS domain
Superfamily:SIS domain
Family:double-SIS domain
28c2amlB_



not modelled 99.7 17 PDB header:transferase
Chain: B: PDB Molecule:sis domain protein;
PDBTitle: crystal structure of lmo0035 protein (46906266) from listeria2 monocytogenes 4b f2365 at 1.50 a resolution
29c3knzA_



not modelled 99.7 18 PDB header:sugar binding protein
Chain: A: PDB Molecule:putative sugar binding protein;
PDBTitle: crystal structure of putative sugar binding protein (np_459565.1) from2 salmonella typhimurium lt2 at 2.50 a resolution
30c3fkjA_



not modelled 99.7 19 PDB header:isomerase
Chain: A: PDB Molecule:putative phosphosugar isomerases;
PDBTitle: crystal structure of a putative phosphosugar isomerase (stm_0572) from2 salmonella typhimurium lt2 at 2.12 a resolution
31c2decA_



not modelled 99.6 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:325aa long hypothetical protein;
PDBTitle: crystal structure of the ph0510 protein from pyrococcus horikoshii ot3
32c1jxaA_



not modelled 99.5 22 PDB header:transferase
Chain: A: PDB Molecule:glucosamine 6-phosphate synthase;
PDBTitle: glucosamine 6-phosphate synthase with glucose 6-phosphate
33c3odpA_



not modelled 99.5 22 PDB header:isomerase
Chain: A: PDB Molecule:putative tagatose-6-phosphate ketose/aldose isomerase;
PDBTitle: crystal structure of a putative tagatose-6-phosphate ketose/aldose2 isomerase (nt01cx_0292) from clostridium novyi nt at 2.35 a3 resolution
34d1x9ia_



not modelled 99.5 23 Fold:SIS domain
Superfamily:SIS domain
Family:double-SIS domain
35c2o3fC_



not modelled 99.4 20 PDB header:transcription
Chain: C: PDB Molecule:putative hth-type transcriptional regulator ybbh;
PDBTitle: structural genomics, the crystal structure of the n-2 terminal domain of the putative transcriptional regulator3 ybbh from bacillus subtilis subsp. subtilis str. 168.
36d2o3fa1



not modelled 99.4 20 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Homeodomain-like
Family:RpiR-like
37c3i0zB_



not modelled 99.4 16 PDB header:isomerase
Chain: B: PDB Molecule:putative tagatose-6-phosphate ketose/aldose isomerase;
PDBTitle: crystal structure of putative putative tagatose-6-phosphate2 ketose/aldose isomerase (np_344614.1) from streptococcus pneumoniae3 tigr4 at 1.70 a resolution
38c3c3jA_



not modelled 99.3 16 PDB header:isomerase
Chain: A: PDB Molecule:putative tagatose-6-phosphate ketose/aldose isomerase;
PDBTitle: crystal structure of tagatose-6-phosphate ketose/aldose isomerase from2 escherichia coli
39c2q8nB_



not modelled 98.2 21 PDB header:isomerase
Chain: B: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: crystal structure of glucose-6-phosphate isomerase (ec2 5.3.1.9) (tm1385) from thermotoga maritima at 1.82 a3 resolution
40c1zzgB_



not modelled 98.2 21 PDB header:isomerase
Chain: B: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: crystal structure of hypothetical protein tt0462 from thermus2 thermophilus hb8
41c3ff1B_



not modelled 97.9 19 PDB header:isomerase
Chain: B: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: structure of glucose 6-phosphate isomerase from staphylococcus aureus
42d1c7qa_



not modelled 97.8 22 Fold:SIS domain
Superfamily:SIS domain
Family:Phosphoglucose isomerase, PGI
43d1gzda_



not modelled 97.2 23 Fold:SIS domain
Superfamily:SIS domain
Family:Phosphoglucose isomerase, PGI
44c3hjbA_



not modelled 97.1 17 PDB header:isomerase
Chain: A: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: 1.5 angstrom crystal structure of glucose-6-phosphate isomerase from2 vibrio cholerae.
45c3jx9B_



not modelled 97.1 10 PDB header:isomerase
Chain: B: PDB Molecule:putative phosphoheptose isomerase;
PDBTitle: crystal structure of putative phosphoheptose isomerase2 (yp_001815198.1) from exiguobacterium sp. 255-15 at 1.95 a resolution
46d1iata_



not modelled 97.1 19 Fold:SIS domain
Superfamily:SIS domain
Family:Phosphoglucose isomerase, PGI
47d1lnwa_



not modelled 97.0 9 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:MarR-like transcriptional regulators
48c3nqoB_



not modelled 97.0 11 PDB header:transcription
Chain: B: PDB Molecule:marr-family transcriptional regulator;
PDBTitle: crystal structure of a marr family transcriptional regulator (cd1569)2 from clostridium difficile 630 at 2.20 a resolution
49c3ljkA_



not modelled 97.0 26 PDB header:isomerase
Chain: A: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: glucose-6-phosphate isomerase from francisella tularensis.
50c2wu8A_



not modelled 97.0 21 PDB header:isomerase
Chain: A: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: structural studies of phosphoglucose isomerase from2 mycobacterium tuberculosis h37rv
51d1hm5a_



not modelled 96.9 20 Fold:SIS domain
Superfamily:SIS domain
Family:Phosphoglucose isomerase, PGI
52c3ujhB_



not modelled 96.9 23 PDB header:isomerase
Chain: B: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: crystal structure of substrate-bound glucose-6-phosphate isomerase2 from toxoplasma gondii
53d1u0fa_



not modelled 96.9 24 Fold:SIS domain
Superfamily:SIS domain
Family:Phosphoglucose isomerase, PGI
54d1q50a_



not modelled 96.8 24 Fold:SIS domain
Superfamily:SIS domain
Family:Phosphoglucose isomerase, PGI
55c3bj6B_



not modelled 96.6 15 PDB header:transcription regulator
Chain: B: PDB Molecule:transcriptional regulator, marr family;
PDBTitle: crystal structure of marr family transcription regulator sp03579
56c3nbuC_



not modelled 96.5 22 PDB header:isomerase
Chain: C: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: crystal structure of pgi glucosephosphate isomerase
57d3broa1



not modelled 96.5 13 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:MarR-like transcriptional regulators
58c2o2cB_



not modelled 96.5 21 PDB header:isomerase
Chain: B: PDB Molecule:glucose-6-phosphate isomerase, glycosomal;
PDBTitle: crystal structure of phosphoglucose isomerase from t. brucei2 containing glucose-6-phosphate in the active site
59c1t10A_



not modelled 96.4 24 PDB header:isomerase
Chain: A: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: phosphoglucose isomerase from leishmania mexicana in complex with2 substrate d-fructose-6-phosphate
60c3pr3B_



not modelled 96.4 28 PDB header:isomerase
Chain: B: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: crystal structure of plasmodium falciparum glucose-6-phosphate2 isomerase (pf14_0341) in complex with fructose-6-phosphate
61c3kp3B_



not modelled 96.3 10 PDB header:transcription regulator/antibiotic
Chain: B: PDB Molecule:transcriptional regulator tcar;
PDBTitle: staphylococcus epidermidis in complex with ampicillin
62c2nnnB_



not modelled 96.2 11 PDB header:transcription
Chain: B: PDB Molecule:probable transcriptional regulator;
PDBTitle: crystal structure of probable transcriptional regulator from2 pseudomonas aeruginosa
63c3g3zA_



not modelled 96.1 13 PDB header:transcription
Chain: A: PDB Molecule:transcriptional regulator, marr family;
PDBTitle: the structure of nmb1585, a marr family regulator from neisseria2 meningitidis
64d2a61a1



not modelled 96.1 17 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:MarR-like transcriptional regulators
65d2etha1



not modelled 96.1 12 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:MarR-like transcriptional regulators
66c2fa5B_



not modelled 96.1 10 PDB header:transcription
Chain: B: PDB Molecule:transcriptional regulator marr/emrr family;
PDBTitle: the crystal structure of an unliganded multiple antibiotic-2 resistance repressor (marr) from xanthomonas campestris
67c2rdpA_



not modelled 96.1 11 PDB header:transcription
Chain: A: PDB Molecule:putative transcriptional regulator marr;
PDBTitle: the structure of a marr family protein from bacillus2 stearothermophilus
68d2fbha1



not modelled 96.0 13 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:MarR-like transcriptional regulators
69c2gxgA_



not modelled 96.0 15 PDB header:transcription
Chain: A: PDB Molecule:146aa long hypothetical transcriptional regulator;
PDBTitle: crystal structure of emrr homolog from hyperthermophilic archaea2 sulfolobus tokodaii strain7
70d1yioa1



not modelled 96.0 21 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:C-terminal effector domain of the bipartite response regulators
Family:GerE-like (LuxR/UhpA family of transcriptional regulators)
71c2zkqb_



not modelled 96.0 9 PDB header:ribosomal protein/rna
Chain: B: PDB Molecule:rna expansion segment es3;
PDBTitle: structure of a mammalian ribosomal 40s subunit within an2 80s complex obtained by docking homology models of the rna3 and proteins into an 8.7 a cryo-em map
72c3frwF_



not modelled 95.9 14 PDB header:structural genomics, unknown function
Chain: F: PDB Molecule:putative trp repressor protein;
PDBTitle: crystal structure of putative trpr protein from ruminococcus obeum
73d1a04a1



not modelled 95.9 19 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:C-terminal effector domain of the bipartite response regulators
Family:GerE-like (LuxR/UhpA family of transcriptional regulators)
74c3k0lA_



not modelled 95.8 19 PDB header:transcription regulator
Chain: A: PDB Molecule:repressor protein;
PDBTitle: crystal structure of putative marr family transcriptional2 regulator from acinetobacter sp. adp
75d1s3ja_



not modelled 95.8 12 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:MarR-like transcriptional regulators
76c3r0aB_



not modelled 95.8 10 PDB header:transcription regulator
Chain: B: PDB Molecule:putative transcriptional regulator;
PDBTitle: possible transcriptional regulator from methanosarcina mazei go1 (gi2 21227196)
77c3bpxB_



not modelled 95.7 10 PDB header:transcription regulator
Chain: B: PDB Molecule:transcriptional regulator;
PDBTitle: crystal structure of marr
78d3deua1



not modelled 95.7 22 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:MarR-like transcriptional regulators
79c3oopA_



not modelled 95.7 15 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:lin2960 protein;
PDBTitle: the structure of a protein with unknown function from listeria innocua2 clip11262
80c3tgnA_



not modelled 95.7 19 PDB header:transcription
Chain: A: PDB Molecule:adc operon repressor adcr;
PDBTitle: crystal structure of the zinc-dependent marr family transcriptional2 regulator adcr in the zn(ii)-bound state
81c1x3uA_



not modelled 95.6 18 PDB header:transcription
Chain: A: PDB Molecule:transcriptional regulatory protein fixj;
PDBTitle: solution structure of the c-terminal transcriptional2 activator domain of fixj from sinorhizobium melilot
82c3gbgA_



not modelled 95.6 21 PDB header:transcription regulator
Chain: A: PDB Molecule:tcp pilus virulence regulatory protein;
PDBTitle: crystal structure of toxt from vibrio cholerae o395
83d1lj9a_



not modelled 95.5 11 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:MarR-like transcriptional regulators
84c3deuB_



not modelled 95.5 21 PDB header:transcription regulator
Chain: B: PDB Molecule:transcriptional regulator slya;
PDBTitle: crystal structure of transcription regulatory protein slya2 from salmonella typhimurium in complex with salicylate3 ligands
85c3cjnA_



not modelled 95.5 13 PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional regulator, marr family;
PDBTitle: crystal structure of transcriptional regulator, marr family, from2 silicibacter pomeroyi
86c3korD_



not modelled 95.4 21 PDB header:transcription
Chain: D: PDB Molecule:possible trp repressor;
PDBTitle: crystal structure of a putative trp repressor from staphylococcus2 aureus
87c3iz6A_



not modelled 95.3 10 PDB header:ribosome
Chain: A: PDB Molecule:40s ribosomal protein sa (s2p);
PDBTitle: localization of the small subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome
88d1fsea_



not modelled 95.3 27 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:C-terminal effector domain of the bipartite response regulators
Family:GerE-like (LuxR/UhpA family of transcriptional regulators)
89c3bjaA_



not modelled 95.3 12 PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional regulator, marr family, putative;
PDBTitle: crystal structure of putative marr-like transcription regulator2 (np_978771.1) from bacillus cereus atcc 10987 at 2.38 a resolution
90c2rnjA_



not modelled 95.2 19 PDB header:transcription
Chain: A: PDB Molecule:response regulator protein vrar;
PDBTitle: nmr structure of the s. aureus vrar dna binding domain
91c3bchA_



not modelled 95.1 9 PDB header:cell adhesion, ribosomal protein
Chain: A: PDB Molecule:40s ribosomal protein sa;
PDBTitle: crystal structure of the human laminin receptor precursor
92c1s1hB_



not modelled 95.1 12 PDB header:ribosome
Chain: B: PDB Molecule:40s ribosomal protein s0-a;
PDBTitle: structure of the ribosomal 80s-eef2-sordarin complex from2 yeast obtained by docking atomic models for rna and protein3 components into a 11.7 a cryo-em map. this file, 1s1h,4 contains 40s subunit. the 60s ribosomal subunit is in file5 1s1i.
93c3oouA_



not modelled 95.0 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:lin2118 protein;
PDBTitle: the structure of a protein with unkown function from listeria innocua
94c3kjxD_



not modelled 95.0 23 PDB header:transcription regulator
Chain: D: PDB Molecule:transcriptional regulator, laci family;
PDBTitle: crystal structure of a transcriptional regulator, lacl2 family protein from silicibacter pomeroyi
95c3mklB_



not modelled 95.0 9 PDB header:transcription regulator
Chain: B: PDB Molecule:hth-type transcriptional regulator gadx;
PDBTitle: crystal structure of dna-binding transcriptional dual regulator from2 escherichia coli k-12
96d1jhfa1



not modelled 95.0 20 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:LexA repressor, N-terminal DNA-binding domain
97c3boqB_



not modelled 95.0 8 PDB header:transcription regulator
Chain: B: PDB Molecule:transcriptional regulator, marr family;
PDBTitle: crystal structure of marr family transcriptional regulator from2 silicibacter pomeroyi
98c2k9sA_



not modelled 94.9 6 PDB header:transcription
Chain: A: PDB Molecule:arabinose operon regulatory protein;
PDBTitle: solution structure of dna binding domain of e. coli arac
99c3nrvC_



not modelled 94.9 13 PDB header:transcription regulator
Chain: C: PDB Molecule:putative transcriptional regulator (marr/emrr family);
PDBTitle: crystal structure of marr/emrr family transcriptional regulator from2 acinetobacter sp. adp1
100c2krfB_



not modelled 94.9 21 PDB header:transcription
Chain: B: PDB Molecule:transcriptional regulatory protein coma;
PDBTitle: nmr solution structure of the dna binding domain of competence protein2 a
101c2l4aA_



not modelled 94.8 19 PDB header:dna binding protein
Chain: A: PDB Molecule:leucine responsive regulatory protein;
PDBTitle: nmr structure of the dna-binding domain of e.coli lrp
102c3e6mD_



not modelled 94.8 17 PDB header:transcription regulator
Chain: D: PDB Molecule:marr family transcriptional regulator;
PDBTitle: the crystal structure of a marr family transcriptional2 regulator from silicibacter pomeroyi dss.
103d2fbia1



not modelled 94.8 16 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:MarR-like transcriptional regulators
104d1p4wa_



not modelled 94.8 23 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:C-terminal effector domain of the bipartite response regulators
Family:GerE-like (LuxR/UhpA family of transcriptional regulators)
105d1l3la1



not modelled 94.8 13 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:C-terminal effector domain of the bipartite response regulators
Family:GerE-like (LuxR/UhpA family of transcriptional regulators)
106d1jhga_



not modelled 94.8 23 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:TrpR-like
Family:Trp repressor, TrpR
107c1zljE_



not modelled 94.8 19 PDB header:transcription
Chain: E: PDB Molecule:dormancy survival regulator;
PDBTitle: crystal structure of the mycobacterium tuberculosis hypoxic2 response regulator dosr c-terminal domain
108c3mn2B_



not modelled 94.8 13 PDB header:transcription regulator
Chain: B: PDB Molecule:probable arac family transcriptional regulator;
PDBTitle: the crystal structure of a probable arac family transcriptional2 regulator from rhodopseudomonas palustris cga009
109d2cg4a1



not modelled 94.7 24 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Lrp/AsnC-like transcriptional regulator N-terminal domain
110c1bdhA_



not modelled 94.6 31 PDB header:transcription/dna
Chain: A: PDB Molecule:protein (purine repressor);
PDBTitle: purine repressor mutant-hypoxanthine-palindromic operator2 complex
111d1jgsa_



not modelled 94.6 12 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:MarR-like transcriptional regulators
112c2qwwB_



not modelled 94.6 17 PDB header:transcription
Chain: B: PDB Molecule:transcriptional regulator, marr family;
PDBTitle: crystal structure of multiple antibiotic-resistance repressor (marr)2 (yp_013417.1) from listeria monocytogenes 4b f2365 at 2.07 a3 resolution
113d2jioa2



not modelled 94.6 14 Fold:Formate dehydrogenase/DMSO reductase, domains 1-3
Superfamily:Formate dehydrogenase/DMSO reductase, domains 1-3
Family:Formate dehydrogenase/DMSO reductase, domains 1-3
114d1stza1



not modelled 94.5 20 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Heat-inducible transcription repressor HrcA, N-terminal domain
115d2cfxa1



not modelled 94.5 17 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Lrp/AsnC-like transcriptional regulator N-terminal domain
116c3lsgD_



not modelled 94.5 10 PDB header:transcription regulator
Chain: D: PDB Molecule:two-component response regulator yesn;
PDBTitle: the crystal structure of the c-terminal domain of the two-2 component response regulator yesn from fusobacterium3 nucleatum subsp. nucleatum atcc 25586
117c3k2zA_



not modelled 94.5 20 PDB header:hydrolase
Chain: A: PDB Molecule:lexa repressor;
PDBTitle: crystal structure of a lexa protein from thermotoga maritima
118c1bl0A_



not modelled 94.5 12 PDB header:transcription/dna
Chain: A: PDB Molecule:protein (multiple antibiotic resistance protein);
PDBTitle: multiple antibiotic resistance protein (mara)/dna complex
119d1trra_



not modelled 94.5 23 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:TrpR-like
Family:Trp repressor, TrpR
120c3ecoB_



not modelled 94.4 12 PDB header:transcription
Chain: B: PDB Molecule:mepr;
PDBTitle: crystal structure of mepr, a transcription regulator of the2 staphylococcus aureus multidrug efflux pump mepa

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0