Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	D	A	L	Q	T	Q	T	V	N	S	T	T	A	P	Q	P	N	Y	I	P	G	L	I	A	V	V	G	C	D	G	T	G	K	S	T	L	T	T	D	L	V	K	S	L	Q	Q	H	W	Q	T	E	R	R	Y	L	G	L	L	S
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																																							?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	E	D	G	D	K	I	K	R	L	P	L	V	G	V	W	L	E	R	R	L	A	A	K	S	S	K	T	Q	S	M	K	T	K	S	P	A	L	W	A	A	V	I	M	Y	C	F	S	L	R	R	M	A	N	L	R	K	V	Q	R
Secondary structure
SS confidence
Disorder		?	?	?	?						?		?	?		?	?	?				?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	A	Q	S	G	V	L	V	V	S	D	R	F	P	Q	A	E	I	S	G	F	Y	Y	D	G	P	G	I	G	V	E	R	A	T	G	K	I	S	M	F	L	A	Q	R	E	R	R	L	Y	Q	Q	M	A	Q	Y	R	P	E	L	I
Secondary structure
SS confidence
Disorder																					?					?	?	?	?	?	?	?	?	?																		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		I	R	L	G	I	D	I	E	T	A	I	S	R	K	P	D	H	D	Y	A	E	L	Q	D	K	I	G	V	M	S	K	I	G	Y	N	G	T	K	I	L	E	I	D	S	R	A	P	Y	S	E	V	L	E	Q	A	Q	K	A	V	S
Secondary structure
SS confidence
Disorder													?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.
Sequence		L	V	A	I	V	S	D	R	R	S	L	T
Secondary structure
SS confidence
Disorder										?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3ld9 chain D Region: 21 - 242 Aligned: 178 Modelled: 193 Confidence: 100.0% Identity: 17% PDB header:transferase Chain: D: PDB Molecule:thymidylate kinase; PDBTitle: crystal structure of thymidylate kinase from ehrlichia chaffeensis at2 2.15a resolution Phyre2 PDB 1gsi chain A Region: 22 - 235 Aligned: 190 Modelled: 197 Confidence: 100.0% Identity: 22% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nucleotide and nucleoside kinases Phyre2 PDB 1tmk chain A Region: 21 - 242 Aligned: 187 Modelled: 202 Confidence: 99.9% Identity: 22% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nucleotide and nucleoside kinases Phyre2 PDB 4tmk chain A Region: 21 - 240 Aligned: 193 Modelled: 205 Confidence: 99.9% Identity: 19% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nucleotide and nucleoside kinases Phyre2 PDB 2w0s chain B Region: 21 - 242 Aligned: 184 Modelled: 191 Confidence: 99.9% Identity: 18% PDB header:transferase Chain: B: PDB Molecule:thymidylate kinase; PDBTitle: crystal structure of vaccinia virus thymidylate kinase2 bound to brivudin-5'-monophosphate Phyre2 PDB 1nn5 chain A Region: 19 - 242 Aligned: 189 Modelled: 204 Confidence: 99.9% Identity: 19% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nucleotide and nucleoside kinases Phyre2 PDB 2ccj chain A Region: 21 - 242 Aligned: 187 Modelled: 190 Confidence: 99.9% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:thymidylate kinase; PDBTitle: crystal structure of s. aureus thymidylate kinase complexed2 with thymidine monophosphate Phyre2 PDB 3lv8 chain A Region: 20 - 239 Aligned: 191 Modelled: 203 Confidence: 99.9% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:thymidylate kinase; PDBTitle: 1.8 angstrom resolution crystal structure of a thymidylate kinase2 (tmk) from vibrio cholerae o1 biovar eltor str. n16961 in complex3 with tmp, thymidine-5'-diphosphate and adp Phyre2 PDB 2ocp chain A domain 1 Region: 20 - 242 Aligned: 199 Modelled: 202 Confidence: 99.9% Identity: 14% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nucleotide and nucleoside kinases Phyre2 PDB 2plr chain B Region: 21 - 242 Aligned: 181 Modelled: 181 Confidence: 99.9% Identity: 19% PDB header:transferase Chain: B: PDB Molecule:probable thymidylate kinase; PDBTitle: crystal structure of dtmp kinase (st1543) from sulfolobus tokodaii2 strain7 Phyre2 PDB 2pbr chain B Region: 22 - 242 Aligned: 188 Modelled: 200 Confidence: 99.9% Identity: 20% PDB header:transferase Chain: B: PDB Molecule:thymidylate kinase; PDBTitle: crystal structure of thymidylate kinase (aq_969) from aquifex aeolicus2 vf5 Phyre2 PDB 2wwi chain C Region: 18 - 239 Aligned: 187 Modelled: 202 Confidence: 99.9% Identity: 21% PDB header:transferase Chain: C: PDB Molecule:thymidilate kinase, putative; PDBTitle: plasmodium falciparum thymidylate kinase in complex with2 aztmp and adp Phyre2 PDB 2z0h chain A Region: 22 - 239 Aligned: 179 Modelled: 180 Confidence: 99.9% Identity: 20% PDB header:transferase Chain: A: PDB Molecule:thymidylate kinase; PDBTitle: crystal structure of thymidylate kinase in complex with dtdp2 and adp from thermotoga maritima Phyre2 PDB 1p5z chain B Region: 22 - 242 Aligned: 196 Modelled: 207 Confidence: 99.8% Identity: 16% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nucleotide and nucleoside kinases Phyre2 PDB 2qro chain B Region: 22 - 242 Aligned: 195 Modelled: 206 Confidence: 99.8% Identity: 16% PDB header:transferase Chain: B: PDB Molecule:deoxycytidine kinase; PDBTitle: human deoxycytidine kinase damp, udp, mg ion product complex Phyre2 PDB 2ql6 chain H Region: 20 - 239 Aligned: 161 Modelled: 164 Confidence: 99.8% Identity: 12% PDB header:signaling protein,transferase Chain: H: PDB Molecule:nicotinamide riboside kinase 1; PDBTitle: human nicotinamide riboside kinase (nrk1) Phyre2 PDB 1p6x chain A Region: 23 - 215 Aligned: 169 Modelled: 193 Confidence: 99.7% Identity: 17% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nucleotide and nucleoside kinases Phyre2 PDB 1e2k chain A Region: 24 - 215 Aligned: 163 Modelled: 180 Confidence: 99.7% Identity: 14% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nucleotide and nucleoside kinases Phyre2 PDB 1knq chain A Region: 18 - 239 Aligned: 162 Modelled: 165 Confidence: 99.7% Identity: 14% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Gluconate kinase Phyre2 PDB 2vp4 chain A domain 1 Region: 18 - 225 Aligned: 177 Modelled: 186 Confidence: 99.7% Identity: 14% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nucleotide and nucleoside kinases Phyre2 PDB 2j7p chain A Region: 7 - 70 Aligned: 64 Modelled: 64 Confidence: 97.6% Identity: 14% PDB header:signal recognition Chain: A: PDB Molecule:signal recognition particle protein; PDBTitle: gmppnp-stabilized ng domain complex of the srp gtpases ffh2 and ftsy Phyre2 PDB 2iy3 chain A Region: 2 - 54 Aligned: 52 Modelled: 52 Confidence: 97.6% Identity: 21% PDB header:rna-binding Chain: A: PDB Molecule:signal recognition particle protein ffh; PDBTitle: structure of the e. coli signal recognition particle2 bound to a translating ribosome Phyre2 1 c3ld9D_ 2 d1gsia_ 3 d1tmka_ 4 d4tmka_ 5 c2w0sB_ 6 d1nn5a_ 7 c2ccjA_ 8 c3lv8A_ 9 d2ocpa1 10 c2plrB_ 11 c2pbrB_ 12 c2wwiC_ 13 c2z0hA_ 14 d1p5zb_ 15 c2qroB_ 16 c2ql6H_ 17 d1p6xa_ 18 d1e2ka_ 19 d1knqa_ 20 d2vp4a1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 c2j7pA_ 134 135 c2iy3A_ 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499