Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	D	N	A	V	D	R	H	V	F	Y	I	S	D	G	T	A	I	T	A	E	V	L	G	H	A	V	M	S	Q	F	P	V	T	I	S	S	I	T	L	P	F	V	E	N	E	S	R	A	R	A	V	K	D	Q	I	D	A	I	Y
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		H	Q	T	G	V	R	P	L	V	F	Y	S	I	V	L	P	E	I	R	A	I	I	L	Q	S	E	G	F	C	Q	D	I	V	Q	A	L	V	A	P	L	Q	Q	E	M	K	L	D	P	T	P	I	A	H	R	T	H	G	L	N	P
Secondary structure
SS confidence
Disorder			?																																										?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		N	N	L	N	K	Y	D	A	R	I	A	A	I	D	Y	T	L	A	H	D	D	G	I	S	L	R	N	L	D	Q	A	Q	V	I	L	L	G	V	S	R	C	G	K	T	P	T	S	L	Y	L	A	M	Q	F	G	I	R	A	A	N
Secondary structure
SS confidence
Disorder		?	?	?																						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Y	P	F	I	A	D	D	M	D	N	L	V	L	P	A	S	L	K	P	L	Q	H	K	L	F	G	L	T	I	D	P	E	R	L	A	A	I	R	E	E	R	R	E	N	S	R	Y	A	S	L	R	Q	C	R	M	E	V	A	E	V
Secondary structure
SS confidence
Disorder							?	?	?	?	?	?	?							?																							?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.
Sequence		E	A	L	Y	R	K	N	Q	I	P	W	I	N	S	T	N	Y	S	V	E	E	I	A	T	K	I	L	D	I	M	G	L	S	R	R	M	Y
Secondary structure
SS confidence
Disorder																																?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2iyv chain A domain 1 Region: 153 - 270 Aligned: 118 Modelled: 118 Confidence: 97.9% Identity: 15% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Shikimate kinase (AroK) Phyre2 PDB 3akc chain A Region: 153 - 272 Aligned: 117 Modelled: 119 Confidence: 97.8% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:cytidylate kinase; PDBTitle: crystal structure of cmp kinase in complex with cdp and adp from2 thermus thermophilus hb8 Phyre2 PDB 3trf chain B Region: 153 - 271 Aligned: 119 Modelled: 119 Confidence: 97.7% Identity: 16% PDB header:transferase Chain: B: PDB Molecule:shikimate kinase; PDBTitle: structure of a shikimate kinase (arok) from coxiella burnetii Phyre2 PDB 1via chain A Region: 153 - 271 Aligned: 119 Modelled: 119 Confidence: 97.7% Identity: 15% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Shikimate kinase (AroK) Phyre2 PDB 1zui chain A Region: 153 - 270 Aligned: 117 Modelled: 118 Confidence: 97.7% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:shikimate kinase; PDBTitle: structural basis for shikimate-binding specificity of helicobacter2 pylori shikimate kinase Phyre2 PDB 1e6c chain A Region: 153 - 272 Aligned: 119 Modelled: 120 Confidence: 97.7% Identity: 19% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Shikimate kinase (AroK) Phyre2 PDB 1cke chain A Region: 153 - 273 Aligned: 114 Modelled: 121 Confidence: 97.6% Identity: 27% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nucleotide and nucleoside kinases Phyre2 PDB 1q3t chain A Region: 153 - 276 Aligned: 122 Modelled: 124 Confidence: 97.6% Identity: 22% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nucleotide and nucleoside kinases Phyre2 PDB 2cdn chain A domain 1 Region: 153 - 272 Aligned: 119 Modelled: 120 Confidence: 97.4% Identity: 25% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nucleotide and nucleoside kinases Phyre2 PDB 2vli chain B Region: 153 - 273 Aligned: 116 Modelled: 121 Confidence: 97.3% Identity: 17% PDB header:transferase Chain: B: PDB Molecule:antibiotic resistance protein; PDBTitle: structure of deinococcus radiodurans tunicamycin resistance2 protein Phyre2 PDB 2bwj chain C Region: 153 - 271 Aligned: 118 Modelled: 118 Confidence: 97.3% Identity: 13% PDB header:transferase Chain: C: PDB Molecule:adenylate kinase 5; PDBTitle: structure of adenylate kinase 5 Phyre2 PDB 2h92 chain C Region: 153 - 272 Aligned: 117 Modelled: 120 Confidence: 97.2% Identity: 22% PDB header:transferase Chain: C: PDB Molecule:cytidylate kinase; PDBTitle: crystal structure of staphylococcus aureus cytidine2 monophosphate kinase in complex with cytidine-5'-3 monophosphate Phyre2 PDB 1kht chain A Region: 153 - 271 Aligned: 119 Modelled: 119 Confidence: 97.1% Identity: 13% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nucleotide and nucleoside kinases Phyre2 PDB 1ak2 chain A domain 1 Region: 145 - 272 Aligned: 125 Modelled: 128 Confidence: 97.1% Identity: 18% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nucleotide and nucleoside kinases Phyre2 PDB 3t61 chain A Region: 153 - 270 Aligned: 112 Modelled: 116 Confidence: 97.0% Identity: 19% PDB header:transferase Chain: A: PDB Molecule:gluconokinase; PDBTitle: crystal structure of a gluconokinase from sinorhizobium meliloti 1021 Phyre2 PDB 2pt5 chain D Region: 153 - 274 Aligned: 111 Modelled: 122 Confidence: 96.9% Identity: 20% PDB header:transferase Chain: D: PDB Molecule:shikimate kinase; PDBTitle: crystal structure of shikimate kinase (aq_2177) from aquifex aeolicus2 vf5 Phyre2 PDB 1tev chain A Region: 153 - 273 Aligned: 120 Modelled: 121 Confidence: 96.9% Identity: 17% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nucleotide and nucleoside kinases Phyre2 PDB 2ccj chain A Region: 153 - 272 Aligned: 117 Modelled: 120 Confidence: 96.8% Identity: 9% PDB header:transferase Chain: A: PDB Molecule:thymidylate kinase; PDBTitle: crystal structure of s. aureus thymidylate kinase complexed2 with thymidine monophosphate Phyre2 PDB 1zp6 chain A domain 1 Region: 153 - 274 Aligned: 120 Modelled: 122 Confidence: 96.8% Identity: 15% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Atu3015-like Phyre2 PDB 1ukz chain A Region: 153 - 273 Aligned: 117 Modelled: 121 Confidence: 96.8% Identity: 17% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nucleotide and nucleoside kinases Phyre2 PDB 2ak2 chain A Region: 145 - 180 Aligned: 33 Modelled: 33 Confidence: 89.4% Identity: 24% PDB header:phosphotransferase Chain: A: PDB Molecule:adenylate kinase isoenzyme-2; PDBTitle: adenylate kinase isoenzyme-2 Phyre2 PDB 3eih chain B Region: 107 - 181 Aligned: 70 Modelled: 70 Confidence: 84.1% Identity: 14% PDB header:protein transport Chain: B: PDB Molecule:vacuolar protein sorting-associated protein 4; PDBTitle: crystal structure of s.cerevisiae vps4 in the presence of atpgammas Phyre2 PDB 3ngl chain A Region: 4 - 178 Aligned: 150 Modelled: 150 Confidence: 73.5% Identity: 10% PDB header:oxidoreductase, hydrolase Chain: A: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of bifunctional 5,10-methylenetetrahydrofolate2 dehydrogenase / cyclohydrolase from thermoplasma acidophilum Phyre2 PDB 1b0a chain A Region: 9 - 178 Aligned: 148 Modelled: 148 Confidence: 70.4% Identity: 14% PDB header:oxidoreductase,hydrolase Chain: A: PDB Molecule:protein (fold bifunctional protein); PDBTitle: 5,10, methylene-tetrahydropholate2 dehydrogenase/cyclohydrolase from e coli. Phyre2 1 d2iyva1 2 c3akcA_ 3 c3trfB_ 4 d1viaa_ 5 c1zuiA_ 6 d1e6ca_ 7 d1ckea_ 8 d1q3ta_ 9 d2cdna1 10 c2vliB_ 11 c2bwjC_ 12 c2h92C_ 13 d1khta_ 14 d1ak2a1 15 c3t61A_ 16 c2pt5D_ 17 d1teva_ 18 c2ccjA_ 19 d1zp6a1 20 d1ukza_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 c2ak2A_ 72 73 74 75 76 77 78 79 80 c3eihB_ 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 c3nglA_ 98 99 100 c1b0aA_ 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d2iyva1 97.9 15 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Shikimate kinase (AroK) 2 c3akcA_ 97.8 21 PDB header:transferase Chain: A: PDB Molecule:cytidylate kinase; PDBTitle: crystal structure of cmp kinase in complex with cdp and adp from2 thermus thermophilus hb8 3 c3trfB_ 97.7 16 PDB header:transferase Chain: B: PDB Molecule:shikimate kinase; PDBTitle: structure of a shikimate kinase (arok) from coxiella burnetii 4 d1viaa_ 97.7 15 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Shikimate kinase (AroK) 5 c1zuiA_ 97.7 22 PDB header:transferase Chain: A: PDB Molecule:shikimate kinase; PDBTitle: structural basis for shikimate-binding specificity of helicobacter2 pylori shikimate kinase 6 d1e6ca_ 97.7 19 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Shikimate kinase (AroK) 7 d1ckea_ 97.6 27 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 8 d1q3ta_ 97.6 22 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 9 d2cdna1 97.4 25 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 10 c2vliB_ 97.3 17 PDB header:transferase Chain: B: PDB Molecule:antibiotic resistance protein; PDBTitle: structure of deinococcus radiodurans tunicamycin resistance2 protein 11 c2bwjC_ 97.3 13 PDB header:transferase Chain: C: PDB Molecule:adenylate kinase 5; PDBTitle: structure of adenylate kinase 5 12 c2h92C_ 97.2 22 PDB header:transferase Chain: C: PDB Molecule:cytidylate kinase; PDBTitle: crystal structure of staphylococcus aureus cytidine2 monophosphate kinase in complex with cytidine-5'-3 monophosphate 13 d1khta_ 97.1 13 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 14 d1ak2a1 97.1 18 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 15 c3t61A_ 97.0 19 PDB header:transferase Chain: A: PDB Molecule:gluconokinase; PDBTitle: crystal structure of a gluconokinase from sinorhizobium meliloti 1021 16 c2pt5D_ 96.9 20 PDB header:transferase Chain: D: PDB Molecule:shikimate kinase; PDBTitle: crystal structure of shikimate kinase (aq_2177) from aquifex aeolicus2 vf5 17 d1teva_ 96.9 17 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 18 c2ccjA_ 96.8 9 PDB header:transferase Chain: A: PDB Molecule:thymidylate kinase; PDBTitle: crystal structure of s. aureus thymidylate kinase complexed2 with thymidine monophosphate 19 d1zp6a1 96.8 15 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Atu3015-like 20 d1ukza_ 96.8 17 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 21 d1ki9a_ not modelled 96.8 15 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 22 c3cm0A_ not modelled 96.7 19 PDB header:transferase Chain: A: PDB Molecule:adenylate kinase; PDBTitle: crystal structure of adenylate kinase from thermus2 thermophilus hb8 23 c3fdiA_ not modelled 96.7 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterized protein from eubacterium2 ventriosum atcc 27560. 24 c2plrB_ not modelled 96.6 15 PDB header:transferase Chain: B: PDB Molecule:probable thymidylate kinase; PDBTitle: crystal structure of dtmp kinase (st1543) from sulfolobus tokodaii2 strain7 25 d1qf9a_ not modelled 96.6 20 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 26 d3adka_ not modelled 96.5 22 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 27 c3akyA_ not modelled 96.5 20 PDB header:adenylate kinase Chain: A: PDB Molecule:adenylate kinase; PDBTitle: stability, activity and structure of adenylate kinase2 mutants 28 d1p3ja1 not modelled 96.5 15 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 29 d1s3ga1 not modelled 96.5 13 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 30 d1e4va1 not modelled 96.4 15 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 31 d1rkba_ not modelled 96.3 25 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 32 c3hdtB_ not modelled 96.3 18 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative kinase; PDBTitle: crystal structure of putative kinase from clostridium symbiosum atcc2 14940 33 c3be4A_ not modelled 96.3 19 PDB header:transferase Chain: A: PDB Molecule:adenylate kinase; PDBTitle: crystal structure of cryptosporidium parvum adenylate kinase cgd5_3360 34 d4tmka_ not modelled 96.3 23 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 35 d1knqa_ not modelled 96.2 17 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Gluconate kinase 36 c3h0kA_ not modelled 96.2 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0200 protein sso1041; PDBTitle: crystal structure of an adenylated kinase related protein from2 sulfolobus solfataricus to 3.25a 37 d1nksa_ not modelled 96.2 22 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 38 c1s3gA_ not modelled 96.1 12 PDB header:transferase Chain: A: PDB Molecule:adenylate kinase; PDBTitle: crystal structure of adenylate kinase from bacillus2 globisporus 39 d1y63a_ not modelled 96.0 13 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 40 d1akya1 not modelled 95.9 16 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 41 d2bdta1 not modelled 95.9 18 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Atu3015-like 42 d1tmka_ not modelled 95.8 20 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 43 d1zina1 not modelled 95.7 18 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 44 d1gsia_ not modelled 95.7 22 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 45 c2yvuA_ not modelled 95.6 12 PDB header:transferase Chain: A: PDB Molecule:probable adenylyl-sulfate kinase; PDBTitle: crystal structure of ape1195 46 d2ak3a1 not modelled 95.6 14 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 47 c2if2C_ not modelled 95.5 15 PDB header:transferase Chain: C: PDB Molecule:dephospho-coa kinase; PDBTitle: crystal structure of the putative dephospho-coa kinase from aquifex2 aeolicus, northeast structural genomics target qr72. 48 c2jatA_ not modelled 95.3 15 PDB header:transferase Chain: A: PDB Molecule:deoxyguanosine kinase; PDBTitle: structure of deoxyadenosine kinase from m.mycoides with2 products dcmp and a flexible dcdp bound 49 c2rh5B_ not modelled 95.3 21 PDB header:transferase Chain: B: PDB Molecule:adenylate kinase; PDBTitle: structure of apo adenylate kinase from aquifex aeolicus 50 c2ql6H_ not modelled 95.1 14 PDB header:signaling protein,transferase Chain: H: PDB Molecule:nicotinamide riboside kinase 1; PDBTitle: human nicotinamide riboside kinase (nrk1) 51 c3crqA_ not modelled 95.0 22 PDB header:transferase Chain: A: PDB Molecule:trna delta(2)-isopentenylpyrophosphate PDBTitle: structure of trna dimethylallyltransferase: rna2 modification through a channel 52 d1zaka1 not modelled 95.0 14 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 53 d1uf9a_ not modelled 94.9 14 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 54 d1lw7a2 not modelled 94.8 17 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 55 d1qhxa_ not modelled 94.7 16 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Chloramphenicol phosphotransferase 56 c3r8cB_ not modelled 94.7 34 PDB header:transferase Chain: B: PDB Molecule:cytidylate kinase; PDBTitle: crystal structure of cytidylate kinase (cmk) from mycobacterium2 abscessus 57 c3lv8A_ not modelled 94.2 22 PDB header:transferase Chain: A: PDB Molecule:thymidylate kinase; PDBTitle: 1.8 angstrom resolution crystal structure of a thymidylate kinase2 (tmk) from vibrio cholerae o1 biovar eltor str. n16961 in complex3 with tmp, thymidine-5'-diphosphate and adp 58 d1x6va3 not modelled 94.1 12 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Adenosine-5'phosphosulfate kinase (APS kinase) 59 c3nwjB_ not modelled 93.9 17 PDB header:transferase Chain: B: PDB Molecule:atsk2; PDBTitle: crystal structure of shikimate kinase from arabidopsis thaliana2 (atsk2) 60 c2eu8B_ not modelled 93.7 13 PDB header:transferase Chain: B: PDB Molecule:adenylate kinase; PDBTitle: crystal structure of a thermostable mutant of bacillus2 subtilis adenylate kinase (q199r) 61 c3tlxA_ not modelled 93.6 24 PDB header:transferase Chain: A: PDB Molecule:adenylate kinase 2; PDBTitle: crystal structure of pf10_0086, adenylate kinase from plasmodium2 falciparum 62 d1kaga_ not modelled 93.3 15 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Shikimate kinase (AroK) 63 d1gkya_ not modelled 93.0 20 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 64 c2ak3B_ not modelled 92.8 15 PDB header:transferase (phosphotransferase) Chain: B: PDB Molecule:adenylate kinase isoenzyme-3; PDBTitle: the three-dimensional structure of the complex between2 mitochondrial matrix adenylate kinase and its substrate3 amp at 1.85 angstroms resolution 65 c3exaD_ not modelled 92.6 14 PDB header:transferase Chain: D: PDB Molecule:trna delta(2)-isopentenylpyrophosphate PDBTitle: crystal structure of the full-length trna2 isopentenylpyrophosphate transferase (bh2366) from3 bacillus halodurans, northeast structural genomics4 consortium target bhr41. 66 d1nn5a_ not modelled 92.2 24 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 67 c2wwiC_ not modelled 91.8 21 PDB header:transferase Chain: C: PDB Molecule:thymidilate kinase, putative; PDBTitle: plasmodium falciparum thymidylate kinase in complex with2 aztmp and adp 68 c3fozB_ not modelled 91.4 22 PDB header:transferase/rna Chain: B: PDB Molecule:trna delta(2)-isopentenylpyrophosphate transferase; PDBTitle: structure of e. coli isopentenyl-trna transferase in complex with e.2 coli trna(phe) 69 c3a8tA_ not modelled 91.1 20 PDB header:transferase Chain: A: PDB Molecule:adenylate isopentenyltransferase; PDBTitle: plant adenylate isopentenyltransferase in complex with atp 70 c2pbrB_ not modelled 90.4 16 PDB header:transferase Chain: B: PDB Molecule:thymidylate kinase; PDBTitle: crystal structure of thymidylate kinase (aq_969) from aquifex aeolicus2 vf5 71 c2ak2A_ 89.4 24 PDB header:phosphotransferase Chain: A: PDB Molecule:adenylate kinase isoenzyme-2; PDBTitle: adenylate kinase isoenzyme-2 72 d1svma_ not modelled 89.3 26 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 73 d1lvga_ not modelled 88.9 17 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 74 c1lw7A_ not modelled 88.9 19 PDB header:transferase Chain: A: PDB Molecule:transcriptional regulator nadr; PDBTitle: nadr protein from haemophilus influenzae 75 c2grjH_ not modelled 88.7 19 PDB header:transferase Chain: H: PDB Molecule:dephospho-coa kinase; PDBTitle: crystal structure of dephospho-coa kinase (ec 2.7.1.24)2 (dephosphocoenzyme a kinase) (tm1387) from thermotoga maritima at3 2.60 a resolution 76 c3d3qB_ not modelled 88.7 16 PDB header:transferase Chain: B: PDB Molecule:trna delta(2)-isopentenylpyrophosphate PDBTitle: crystal structure of trna delta(2)-isopentenylpyrophosphate2 transferase (se0981) from staphylococcus epidermidis.3 northeast structural genomics consortium target ser100 77 c3eplA_ not modelled 87.6 24 PDB header:transferase/rna Chain: A: PDB Molecule:trna isopentenyltransferase; PDBTitle: crystallographic snapshots of eukaryotic2 dimethylallyltransferase acting on trna: insight into trna3 recognition and reaction mechanism 78 c1znyA_ not modelled 87.0 13 PDB header:transferase Chain: A: PDB Molecule:guanylate kinase; PDBTitle: crystal structure of mycobacterium tuberculosis guanylate kinase in2 complex with gdp 79 c3tr0A_ not modelled 84.6 19 PDB header:transferase Chain: A: PDB Molecule:guanylate kinase; PDBTitle: structure of guanylate kinase (gmk) from coxiella burnetii 80 c3eihB_ 84.1 14 PDB header:protein transport Chain: B: PDB Molecule:vacuolar protein sorting-associated protein 4; PDBTitle: crystal structure of s.cerevisiae vps4 in the presence of atpgammas 81 d1jjva_ not modelled 83.3 26 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 82 c2rhmD_ not modelled 83.0 29 PDB header:unknown function Chain: D: PDB Molecule:putative kinase; PDBTitle: crystal structure of a putative kinase (caur_3907) from chloroflexus2 aurantiacus j-10-fl at 1.70 a resolution 83 c2ar7A_ not modelled 82.6 25 PDB header:transferase Chain: A: PDB Molecule:adenylate kinase 4; PDBTitle: crystal structure of human adenylate kinase 4, ak4 84 c3asyB_ not modelled 82.2 19 PDB header:transferase Chain: B: PDB Molecule:uridine kinase; PDBTitle: ligand-free structure of uridine kinase from thermus thermophilus hb8 85 c1zakB_ not modelled 82.2 14 PDB header:transferase Chain: B: PDB Molecule:adenylate kinase; PDBTitle: adenylate kinase from maize in complex with the inhibitor2 p1,p5-bis(adenosine-5'-)pentaphosphate (ap5a) 86 c2f6rA_ not modelled 81.4 16 PDB header:transferase Chain: A: PDB Molecule:bifunctional coenzyme a synthase; PDBTitle: crystal structure of bifunctional coenzyme a synthase (coa synthase):2 (18044849) from mus musculus at 1.70 a resolution 87 c2ze5A_ not modelled 81.2 21 PDB header:transferase Chain: A: PDB Molecule:isopentenyl transferase; PDBTitle: crystal structure of adenosine phosphate-isopentenyltransferase 88 d1vhta_ not modelled 80.8 30 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 89 c1ankA_ not modelled 79.4 29 PDB header:transferase(phosphotransferase) Chain: A: PDB Molecule:adenylate kinase; PDBTitle: the closed conformation of a highly flexible protein: the2 structure of e. coli adenylate kinase with bound amp and3 amppnp 90 c2xb4A_ not modelled 78.1 12 PDB header:transferase Chain: A: PDB Molecule:adenylate kinase; PDBTitle: crystal structures of zinc containing adenylate kinase from2 desulfovibrio gigas 91 c3gmtB_ not modelled 76.1 38 PDB header:transferase Chain: B: PDB Molecule:adenylate kinase; PDBTitle: crystal structure of adenylate kinase from burkholderia pseudomallei 92 c3ch4B_ not modelled 75.7 17 PDB header:transferase Chain: B: PDB Molecule:phosphomevalonate kinase; PDBTitle: the crystal structure of human phosphomavelonate kinase at2 1.8 a resolution 93 d1m7gb_ not modelled 75.5 29 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Adenosine-5'phosphosulfate kinase (APS kinase) 94 d1fnna2 not modelled 74.5 21 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 95 c1lnzA_ not modelled 74.4 27 PDB header:cell cycle Chain: A: PDB Molecule:spo0b-associated gtp-binding protein; PDBTitle: structure of the obg gtp-binding protein 96 c1udxA_ not modelled 73.9 22 PDB header:protein binding Chain: A: PDB Molecule:the gtp-binding protein obg; PDBTitle: crystal structure of the conserved protein tt1381 from thermus2 thermophilus hb8 97 c3nglA_ 73.5 10 PDB header:oxidoreductase, hydrolase Chain: A: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of bifunctional 5,10-methylenetetrahydrofolate2 dehydrogenase / cyclohydrolase from thermoplasma acidophilum 98 c3d8bB_ not modelled 72.2 18 PDB header:hydrolase Chain: B: PDB Molecule:fidgetin-like protein 1; PDBTitle: crystal structure of human fidgetin-like protein 1 in complex with adp 99 c2qorA_ not modelled 71.4 16 PDB header:transferase Chain: A: PDB Molecule:guanylate kinase; PDBTitle: crystal structure of plasmodium vivax guanylate kinase 100 c1b0aA_ 70.4 14 PDB header:oxidoreductase,hydrolase Chain: A: PDB Molecule:protein (fold bifunctional protein); PDBTitle: 5,10, methylene-tetrahydropholate2 dehydrogenase/cyclohydrolase from e coli. 101 d1yj5a2 not modelled 69.4 21 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 102 c2gksB_ not modelled 68.5 30 PDB header:transferase Chain: B: PDB Molecule:bifunctional sat/aps kinase; PDBTitle: crystal structure of the bi-functional atp sulfurylase-aps kinase from2 aquifex aeolicus, a chemolithotrophic thermophile 103 d1m8pa3 not modelled 68.4 21 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:ATP sulfurylase C-terminal domain 104 c2w58B_ not modelled 66.3 22 PDB header:hydrolase Chain: B: PDB Molecule:primosome component (helicase loader); PDBTitle: crystal structure of the dnai 105 c4a26B_ not modelled 65.1 10 PDB header:oxidoreductase Chain: B: PDB Molecule:putative c-1-tetrahydrofolate synthase, cytoplasmic; PDBTitle: the crystal structure of leishmania major n5,n10-2 methylenetetrahydrofolate dehydrogenase/cyclohydrolase 106 d1kgda_ not modelled 64.9 26 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 107 c4a5oB_ not modelled 64.1 14 PDB header:oxidoreductase Chain: B: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of pseudomonas aeruginosa n5, n10-2 methylenetetrahydrofolate dehydrogenase-cyclohydrolase (fold) 108 c2qgzA_ not modelled 64.0 19 PDB header:hydrolase Chain: A: PDB Molecule:putative primosome component; PDBTitle: crystal structure of a putative primosome component from2 streptococcus pyogenes serotype m3. northeast structural3 genomics target dr58 109 c3b9qA_ not modelled 63.2 21 PDB header:protein transport Chain: A: PDB Molecule:chloroplast srp receptor homolog, alpha subunit PDBTitle: the crystal structure of cpftsy from arabidopsis thaliana 110 d1lv7a_ not modelled 61.7 14 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 111 c1z6gA_ not modelled 61.6 12 PDB header:transferase Chain: A: PDB Molecule:guanylate kinase; PDBTitle: crystal structure of guanylate kinase from plasmodium falciparum 112 c3neyC_ not modelled 61.5 24 PDB header:membrane protein Chain: C: PDB Molecule:55 kda erythrocyte membrane protein; PDBTitle: crystal structure of the kinase domain of mpp1/p55 113 c2c2xB_ not modelled 60.3 17 PDB header:oxidoreductase Chain: B: PDB Molecule:methylenetetrahydrofolate dehydrogenase- PDBTitle: three dimensional structure of bifunctional2 methylenetetrahydrofolate dehydrogenase-cyclohydrolase3 from mycobacterium tuberculosis 114 d1m7ga_ not modelled 60.3 14 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Adenosine-5'phosphosulfate kinase (APS kinase) 115 c3h4mC_ not modelled 60.2 21 PDB header:hydrolase Chain: C: PDB Molecule:proteasome-activating nucleotidase; PDBTitle: aaa atpase domain of the proteasome- activating nucleotidase 116 d1kkma_ not modelled 59.7 42 Fold:PEP carboxykinase-like Superfamily:PEP carboxykinase-like Family:HPr kinase HprK C-terminal domain 117 c2j7pA_ not modelled 59.5 26 PDB header:signal recognition Chain: A: PDB Molecule:signal recognition particle protein; PDBTitle: gmppnp-stabilized ng domain complex of the srp gtpases ffh2 and ftsy 118 d1rz3a_ not modelled 59.1 29 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Phosphoribulokinase/pantothenate kinase 119 c3b9pA_ not modelled 58.6 12 PDB header:hydrolase Chain: A: PDB Molecule:cg5977-pa, isoform a; PDBTitle: spastin 120 d1s96a_ not modelled 57.5 16 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0