Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionQ46820
DateThu Jan 5 12:34:45 GMT 2012
Unique Job ID35aaf9cd758c17d6

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1gthD_
Top template information
PDB header:oxidoreductase
Chain: D: PDB Molecule:dihydropyrimidine dehydrogenase;
PDBTitle: dihydropyrimidine dehydrogenase (dpd) from pig, ternary2 complex with nadph and 5-iodouracil
Confidence and coverage
Confidence:100.0% Coverage: 69%
438 residues ( 69% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
608 residues ( 95%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MNKFIAAEAAECIGCHACEIACAVAHNQENWPLSHSDFRPRIHVVGKGQAANPVACHHCN
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   .........70.........80.........90.........100.........110.........120
Sequence  NAPCVTACPVNALTFQSDSVQLDEQKCIGCKRCAIACPFGVVEMVDTIAQKCDLCNQRSS
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   .........130.........140.........150.........160.........170.........180
Sequence  GTQACIEVCPTQALRLMDDKGLQQIKVARQRKTAAGKASSDAQPSRSAALLPVNSRKGAD
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?
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??????
?
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   .........190.........200.........210.........220.........230.........240
Sequence  KISASERKTHFGEIYCGLDPQQATYESDRCVYCAEKANCNWHCPLHNAIPDYIRLVQEGK
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Disorder  ??????
?

?


?
?
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   .........250.........260.........270.........280.........290.........300
Sequence  IIEAAELCHQTSSLPEICGRVCPQDRLCEGACTLKDHSGAVSIGNLERYITDTALAMGWR
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?
?????????














?
??
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   .........310.........320.........330.........340.........350.........360
Sequence  PDVSKVVPRSEKVAVIGAGPAGLGCADILARAGVQVDVFDRHPEIGGMLTFGIPPFKLDK
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   .........370.........380.........390.........400.........410.........420
Sequence  TVLSQRREIFTAMGIDFHLNCEIGRDITFSDLTSEYDAVFIGVGTYGMMRADLPHEDAPG
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   .........430.........440.........450.........460.........470.........480
Sequence  VIQALPFLTAHTRQLMGLPESEEYPLTDVEGKRVVVLGGGDTTMDCLRTSIRLNAASVTC
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   .........490.........500.........510.........520.........530.........540
Sequence  AYRRDEVSMPGSRKEVVNAREEGVEFQFNVQPQYIACDEDGRLTAVGLIRTAMGEPGPDG
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??
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   .........550.........560.........570.........580.........590.........600
Sequence  RRRPRPVAGSEFELPADVLIMAFGFQAHAMPWLQGSGIKLDKWGLIQTGDVGYLPTQTHL
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?????
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?
?

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   .........610.........620.........630.........
Sequence  KKVFAGGDAVHGADLVVTAMAAGRQAARDMLTLFDTKAS
Secondary structure 








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?????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1gth chain D

3D model

Region: 189 - 637
Aligned: 438
Modelled: 449
Confidence: 100.0%
Identity: 31%
PDB header:oxidoreductase
Chain: D: PDB Molecule:dihydropyrimidine dehydrogenase;
PDBTitle: dihydropyrimidine dehydrogenase (dpd) from pig, ternary2 complex with nadph and 5-iodouracil

Phyre2

PDB 2vdc chain I

3D model

Region: 189 - 638
Aligned: 444
Modelled: 450
Confidence: 100.0%
Identity: 41%
PDB header:oxidoreductase
Chain: I: PDB Molecule:glutamate synthase [nadph] small chain;
PDBTitle: the 9.5 a resolution structure of glutamate synthase from2 cryo-electron microscopy and its oligomerization behavior3 in solution: functional implications.

Phyre2

PDB 2v6o chain A

3D model

Region: 218 - 639
Aligned: 381
Modelled: 404
Confidence: 100.0%
Identity: 21%
PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin glutathione reductase;
PDBTitle: structure of schistosoma mansoni thioredoxin-glutathione2 reductase (smtgr)

Phyre2

PDB 1cjc chain A

3D model

Region: 311 - 636
Aligned: 312
Modelled: 323
Confidence: 100.0%
Identity: 25%
PDB header:oxidoreductase
Chain: A: PDB Molecule:protein (adrenodoxin reductase);
PDBTitle: structure of adrenodoxin reductase of mitochondrial p4502 systems

Phyre2

PDB 1lqt chain B

3D model

Region: 309 - 636
Aligned: 311
Modelled: 325
Confidence: 100.0%
Identity: 24%
PDB header:oxidoreductase
Chain: B: PDB Molecule:fpra;
PDBTitle: a covalent modification of nadp+ revealed by the atomic resolution2 structure of fpra, a mycobacterium tuberculosis oxidoreductase

Phyre2

PDB 1hyu chain A

3D model

Region: 308 - 634
Aligned: 298
Modelled: 312
Confidence: 100.0%
Identity: 16%
PDB header:oxidoreductase
Chain: A: PDB Molecule:alkyl hydroperoxide reductase subunit f;
PDBTitle: crystal structure of intact ahpf

Phyre2

PDB 1ti2 chain F

3D model

Region: 1 - 160
Aligned: 160
Modelled: 160
Confidence: 100.0%
Identity: 23%
PDB header:oxidoreductase
Chain: F: PDB Molecule:pyrogallol hydroxytransferase small subunit;
PDBTitle: crystal structure of pyrogallol-phloroglucinol2 transhydroxylase from pelobacter acidigallici

Phyre2

PDB 1kqf chain B

3D model

Region: 4 - 149
Aligned: 146
Modelled: 146
Confidence: 100.0%
Identity: 27%
PDB header:oxidoreductase
Chain: B: PDB Molecule:formate dehydrogenase, nitrate-inducible, iron-sulfur
PDBTitle: formate dehydrogenase n from e. coli

Phyre2

PDB 3nta chain A

3D model

Region: 310 - 631
Aligned: 303
Modelled: 315
Confidence: 100.0%
Identity: 19%
PDB header:oxidoreductase
Chain: A: PDB Molecule:fad-dependent pyridine nucleotide-disulphide
PDBTitle: structure of the shewanella loihica pv-4 nadh-dependent persulfide2 reductase

Phyre2

PDB 2ivf chain B

3D model

Region: 2 - 141
Aligned: 140
Modelled: 140
Confidence: 100.0%
Identity: 24%
PDB header:oxidoreductase
Chain: B: PDB Molecule:ethylbenzene dehydrogenase beta-subunit;
PDBTitle: ethylbenzene dehydrogenase from aromatoleum aromaticum

Phyre2

PDB 1kqf chain B domain 1

3D model

Region: 1 - 149
Aligned: 149
Modelled: 149
Confidence: 100.0%
Identity: 28%
Fold: Ferredoxin-like
Superfamily: 4Fe-4S ferredoxins
Family: Ferredoxin domains from multidomain proteins

Phyre2

PDB 1djn chain B

3D model

Region: 293 - 638
Aligned: 321
Modelled: 346
Confidence: 100.0%
Identity: 19%
PDB header:oxidoreductase
Chain: B: PDB Molecule:trimethylamine dehydrogenase;
PDBTitle: structural and biochemical characterization of recombinant wild type2 trimethylamine dehydrogenase from methylophilus methylotrophus (sp.3 w3a1)

Phyre2

PDB 2c3d chain B

3D model

Region: 273 - 631
Aligned: 321
Modelled: 327
Confidence: 100.0%
Identity: 21%
PDB header:oxidoreductase
Chain: B: PDB Molecule:2-oxopropyl-com reductase;
PDBTitle: 2.15 angstrom crystal structure of 2-ketopropyl coenzyme m2 oxidoreductase carboxylase with a coenzyme m disulfide3 bound at the active site

Phyre2

PDB 3k30 chain B

3D model

Region: 230 - 639
Aligned: 339
Modelled: 358
Confidence: 100.0%
Identity: 19%
PDB header:oxidoreductase
Chain: B: PDB Molecule:histamine dehydrogenase;
PDBTitle: histamine dehydrogenase from nocardiodes simplex

Phyre2

PDB 3icr chain A

3D model

Region: 310 - 631
Aligned: 283
Modelled: 298
Confidence: 100.0%
Identity: 22%
PDB header:oxidoreductase
Chain: A: PDB Molecule:coenzyme a-disulfide reductase;
PDBTitle: crystal structure of oxidized bacillus anthracis coadr-rhd

Phyre2

PDB 1h0h chain B

3D model

Region: 2 - 149
Aligned: 148
Modelled: 148
Confidence: 100.0%
Identity: 24%
Fold: Ferredoxin-like
Superfamily: 4Fe-4S ferredoxins
Family: Ferredoxin domains from multidomain proteins

Phyre2

PDB 2vpy chain B

3D model

Region: 1 - 149
Aligned: 149
Modelled: 149
Confidence: 100.0%
Identity: 28%
PDB header:oxidoreductase
Chain: B: PDB Molecule:nrfc protein;
PDBTitle: polysulfide reductase with bound quinone inhibitor,2 pentachlorophenol (pcp)

Phyre2

PDB 1ps9 chain A

3D model

Region: 230 - 630
Aligned: 310
Modelled: 323
Confidence: 100.0%
Identity: 25%
PDB header:oxidoreductase
Chain: A: PDB Molecule:2,4-dienoyl-coa reductase;
PDBTitle: the crystal structure and reaction mechanism of e. coli 2,4-2 dienoyl coa reductase

Phyre2

PDB 1gte chain A domain 1

3D model

Region: 188 - 313
Aligned: 125
Modelled: 126
Confidence: 100.0%
Identity: 30%
Fold: Globin-like
Superfamily: alpha-helical ferredoxin
Family: Dihydropyrimidine dehydrogenase, N-terminal domain

Phyre2

PDB 3oc4 chain A

3D model

Region: 312 - 631
Aligned: 262
Modelled: 282
Confidence: 100.0%
Identity: 23%
PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase, pyridine nucleotide-disulfide family;
PDBTitle: crystal structure of a pyridine nucleotide-disulfide family2 oxidoreductase from the enterococcus faecalis v583

Phyre2
1

c1gthD_
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c2vdcI_
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c2v6oA_
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c1cjcA_
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c1lqtB_
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c1hyuA_
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c1ti2F_
8

c1kqfB_
9

c3ntaA_
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c2ivfB_
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d1kqfb1
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c1djnB_
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c2c3dB_
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c3k30B_
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c3icrA_
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d1h0hb_
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c2vpyB_
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c1ps9A_
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d1gtea1
20

c3oc4A_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1gthD_



100.0 31 PDB header:oxidoreductase
Chain: D: PDB Molecule:dihydropyrimidine dehydrogenase;
PDBTitle: dihydropyrimidine dehydrogenase (dpd) from pig, ternary2 complex with nadph and 5-iodouracil
2c2vdcI_



100.0 41 PDB header:oxidoreductase
Chain: I: PDB Molecule:glutamate synthase [nadph] small chain;
PDBTitle: the 9.5 a resolution structure of glutamate synthase from2 cryo-electron microscopy and its oligomerization behavior3 in solution: functional implications.
3c2v6oA_



100.0 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin glutathione reductase;
PDBTitle: structure of schistosoma mansoni thioredoxin-glutathione2 reductase (smtgr)
4c1cjcA_



100.0 25 PDB header:oxidoreductase
Chain: A: PDB Molecule:protein (adrenodoxin reductase);
PDBTitle: structure of adrenodoxin reductase of mitochondrial p4502 systems
5c1lqtB_



100.0 24 PDB header:oxidoreductase
Chain: B: PDB Molecule:fpra;
PDBTitle: a covalent modification of nadp+ revealed by the atomic resolution2 structure of fpra, a mycobacterium tuberculosis oxidoreductase
6c1hyuA_



100.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:alkyl hydroperoxide reductase subunit f;
PDBTitle: crystal structure of intact ahpf
7c1ti2F_



100.0 23 PDB header:oxidoreductase
Chain: F: PDB Molecule:pyrogallol hydroxytransferase small subunit;
PDBTitle: crystal structure of pyrogallol-phloroglucinol2 transhydroxylase from pelobacter acidigallici
8c1kqfB_



100.0 27 PDB header:oxidoreductase
Chain: B: PDB Molecule:formate dehydrogenase, nitrate-inducible, iron-sulfur
PDBTitle: formate dehydrogenase n from e. coli
9c3ntaA_



100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:fad-dependent pyridine nucleotide-disulphide
PDBTitle: structure of the shewanella loihica pv-4 nadh-dependent persulfide2 reductase
10c2ivfB_



100.0 24 PDB header:oxidoreductase
Chain: B: PDB Molecule:ethylbenzene dehydrogenase beta-subunit;
PDBTitle: ethylbenzene dehydrogenase from aromatoleum aromaticum
11d1kqfb1



100.0 28 Fold:Ferredoxin-like
Superfamily:4Fe-4S ferredoxins
Family:Ferredoxin domains from multidomain proteins
12c1djnB_



100.0 19 PDB header:oxidoreductase
Chain: B: PDB Molecule:trimethylamine dehydrogenase;
PDBTitle: structural and biochemical characterization of recombinant wild type2 trimethylamine dehydrogenase from methylophilus methylotrophus (sp.3 w3a1)
13c2c3dB_



100.0 21 PDB header:oxidoreductase
Chain: B: PDB Molecule:2-oxopropyl-com reductase;
PDBTitle: 2.15 angstrom crystal structure of 2-ketopropyl coenzyme m2 oxidoreductase carboxylase with a coenzyme m disulfide3 bound at the active site
14c3k30B_



100.0 19 PDB header:oxidoreductase
Chain: B: PDB Molecule:histamine dehydrogenase;
PDBTitle: histamine dehydrogenase from nocardiodes simplex
15c3icrA_



100.0 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:coenzyme a-disulfide reductase;
PDBTitle: crystal structure of oxidized bacillus anthracis coadr-rhd
16d1h0hb_



100.0 24 Fold:Ferredoxin-like
Superfamily:4Fe-4S ferredoxins
Family:Ferredoxin domains from multidomain proteins
17c2vpyB_



100.0 28 PDB header:oxidoreductase
Chain: B: PDB Molecule:nrfc protein;
PDBTitle: polysulfide reductase with bound quinone inhibitor,2 pentachlorophenol (pcp)
18c1ps9A_



100.0 25 PDB header:oxidoreductase
Chain: A: PDB Molecule:2,4-dienoyl-coa reductase;
PDBTitle: the crystal structure and reaction mechanism of e. coli 2,4-2 dienoyl coa reductase
19d1gtea1



100.0 30 Fold:Globin-like
Superfamily:alpha-helical ferredoxin
Family:Dihydropyrimidine dehydrogenase, N-terminal domain
20c3oc4A_



100.0 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase, pyridine nucleotide-disulfide family;
PDBTitle: crystal structure of a pyridine nucleotide-disulfide family2 oxidoreductase from the enterococcus faecalis v583
21c3iwaA_



not modelled 100.0 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:fad-dependent pyridine nucleotide-disulphide
PDBTitle: crystal structure of a fad-dependent pyridine nucleotide-disulphide2 oxidoreductase from desulfovibrio vulgaris
22c2bcpA_



not modelled 100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadh oxidase;
PDBTitle: structural analysis of streptococcus pyogenes nadh oxidase:2 c44s nox with azide
23c3kd9B_



not modelled 100.0 25 PDB header:oxidoreductase
Chain: B: PDB Molecule:coenzyme a disulfide reductase;
PDBTitle: crystal structure of pyridine nucleotide disulfide oxidoreductase from2 pyrococcus horikoshii
24c2v3aA_



not modelled 100.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:rubredoxin reductase;
PDBTitle: crystal structure of rubredoxin reductase from pseudomonas2 aeruginosa.
25c2gr2A_



not modelled 100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:ferredoxin reductase;
PDBTitle: crystal structure of ferredoxin reductase, bpha4 (oxidized form)
26c3ic9D_



not modelled 100.0 18 PDB header:oxidoreductase
Chain: D: PDB Molecule:dihydrolipoamide dehydrogenase;
PDBTitle: the structure of dihydrolipoamide dehydrogenase from colwellia2 psychrerythraea 34h.
27c2eq8E_



not modelled 100.0 23 PDB header:oxidoreductase
Chain: E: PDB Molecule:pyruvate dehydrogenase complex, dihydrolipoamide
PDBTitle: crystal structure of lipoamide dehydrogenase from thermus thermophilus2 hb8 with psbdp
28c2zbwA_



not modelled 100.0 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin reductase;
PDBTitle: crystal structure of thioredoxin reductase-like protein from thermus2 thermophilus hb8
29c1q1wA_



not modelled 100.0 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:putidaredoxin reductase;
PDBTitle: crystal structure of putidaredoxin reductase from2 pseudomonas putida
30c1yqzA_



not modelled 100.0 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:coenzyme a disulfide reductase;
PDBTitle: structure of coenzyme a-disulfide reductase from2 staphylococcus aureus refined at 1.54 angstrom resolution
31c3r9uA_



not modelled 100.0 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin reductase;
PDBTitle: thioredoxin-disulfide reductase from campylobacter jejuni.
32c3urhB_



not modelled 100.0 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:dihydrolipoyl dehydrogenase;
PDBTitle: crystal structure of a dihydrolipoamide dehydrogenase from2 sinorhizobium meliloti 1021
33c1ojtA_



not modelled 100.0 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:surface protein;
PDBTitle: structure of dihydrolipoamide dehydrogenase
34d1vlfn2



not modelled 100.0 24 Fold:Ferredoxin-like
Superfamily:4Fe-4S ferredoxins
Family:Ferredoxin domains from multidomain proteins
35c1gv4A_



not modelled 100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:programed cell death protein 8;
PDBTitle: murine apoptosis-inducing factor (aif)
36c1x31A_



not modelled 100.0 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:sarcosine oxidase alpha subunit;
PDBTitle: crystal structure of heterotetrameric sarcosine oxidase from2 corynebacterium sp. u-96
37c1xdiA_



not modelled 100.0 21 PDB header:unknown function
Chain: A: PDB Molecule:rv3303c-lpda;
PDBTitle: crystal structure of lpda (rv3303c) from mycobacterium tuberculosis
38c1zmcG_



not modelled 100.0 22 PDB header:oxidoreductase
Chain: G: PDB Molecule:dihydrolipoyl dehydrogenase;
PDBTitle: crystal structure of human dihydrolipoamide dehydrogenase2 complexed to nad+
39c3d8xB_



not modelled 100.0 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:thioredoxin reductase 1;
PDBTitle: crystal structure of saccharomyces cerevisiae nadph dependent2 thioredoxin reductase 1
40c1zx9A_



not modelled 100.0 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:mercuric reductase;
PDBTitle: crystal structure of tn501 mera
41d1y5ib1



not modelled 100.0 24 Fold:Ferredoxin-like
Superfamily:4Fe-4S ferredoxins
Family:Ferredoxin domains from multidomain proteins
42c2cduB_



not modelled 100.0 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:nadph oxidase;
PDBTitle: the crystal structure of water-forming nad(p)h oxidase from2 lactobacillus sanfranciscensis
43c3ef6A_



not modelled 100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:toluene 1,2-dioxygenase system ferredoxin--nad(+)
PDBTitle: crystal structure of toluene 2,3-dioxygenase reductase
44c2hqmB_



not modelled 100.0 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:glutathione reductase;
PDBTitle: crystal structure of glutathione reductase glr1 from the yeast2 saccharomyces cerevisiae
45c1ebdB_



not modelled 100.0 21 PDB header:complex (oxidoreductase/transferase)
Chain: B: PDB Molecule:dihydrolipoamide dehydrogenase;
PDBTitle: dihydrolipoamide dehydrogenase complexed with the binding2 domain of the dihydrolipoamide acetylase
46c1vdcA_



not modelled 100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadph dependent thioredoxin reductase;
PDBTitle: structure of nadph dependent thioredoxin reductase
47c3lxdA_



not modelled 100.0 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:fad-dependent pyridine nucleotide-disulphide
PDBTitle: crystal structure of ferredoxin reductase arr from novosphingobium2 aromaticivorans
48c1v59B_



not modelled 100.0 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:dihydrolipoamide dehydrogenase;
PDBTitle: crystal structure of yeast lipoamide dehydrogenase2 complexed with nad+
49c2qaeA_



not modelled 100.0 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydrolipoyl dehydrogenase;
PDBTitle: crystal structure analysis of trypanosoma cruzi lipoamide2 dehydrogenase
50c2a8xA_



not modelled 100.0 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydrolipoyl dehydrogenase;
PDBTitle: crystal structure of lipoamide dehydrogenase from2 mycobacterium tuberculosis
51c2eq7B_



not modelled 100.0 22 PDB header:oxidoreductase
Chain: B: PDB Molecule:2-oxoglutarate dehydrogenase e3 component;
PDBTitle: crystal structure of lipoamide dehydrogenase from thermus thermophilus2 hb8 with psbdo
52c1dxlC_



not modelled 100.0 20 PDB header:oxidoreductase
Chain: C: PDB Molecule:dihydrolipoamide dehydrogenase;
PDBTitle: dihydrolipoamide dehydrogenase of glycine decarboxylase2 from pisum sativum
53c1bwcA_



not modelled 100.0 25 PDB header:oxidoreductase
Chain: A: PDB Molecule:protein (glutathione reductase);
PDBTitle: structure of human glutathione reductase complexed with ajoene2 inhibitor and subversive substrate
54c1lpfB_



not modelled 100.0 23 PDB header:oxidoreductase
Chain: B: PDB Molecule:dihydrolipoamide dehydrogenase;
PDBTitle: three-dimensional structure of lipoamide dehydrogenase from2 pseudomonas fluorescens at 2.8 angstroms resolution.3 analysis of redox and thermostability properties
55c1tytA_



not modelled 100.0 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:trypanothione reductase, oxidized form;
PDBTitle: crystal and molecular structure of crithidia fasciculata2 trypanothione reductase at 2.6 angstroms resolution
56c1nhqA_



not modelled 100.0 21 PDB header:oxidoreductase (h2o2(a))
Chain: A: PDB Molecule:nadh peroxidase;
PDBTitle: crystallographic analyses of nadh peroxidase cys42ala and cys42ser2 mutants: active site structure, mechanistic implications, and an3 unusual environment of arg303
57c3fg2P_



not modelled 100.0 19 PDB header:oxidoreductase
Chain: P: PDB Molecule:putative rubredoxin reductase;
PDBTitle: crystal structure of ferredoxin reductase for the cyp199a2 system from2 rhodopseudomonas palustris
58c3o0hA_



not modelled 100.0 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:glutathione reductase;
PDBTitle: crystal structure of glutathione reductase from bartonella henselae
59c3lzxB_



not modelled 100.0 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:ferredoxin--nadp reductase 2;
PDBTitle: crystal structure of ferredoxin-nadp+ oxidoreductase from bacillus2 subtilis (form ii)
60c1geuA_



not modelled 100.0 19 PDB header:oxidoreductase(flavoenzyme)
Chain: A: PDB Molecule:glutathione reductase;
PDBTitle: anatomy of an engineered nad-binding site
61c3l8kB_



not modelled 100.0 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:dihydrolipoyl dehydrogenase;
PDBTitle: crystal structure of a dihydrolipoyl dehydrogenase from2 sulfolobus solfataricus
62c1f6mF_



not modelled 100.0 20 PDB header:oxidoreductase
Chain: F: PDB Molecule:thioredoxin reductase;
PDBTitle: crystal structure of a complex between thioredoxin2 reductase, thioredoxin, and the nadp+ analog, aadp+
63c2r9zB_



not modelled 100.0 24 PDB header:oxidoreductase
Chain: B: PDB Molecule:glutathione amide reductase;
PDBTitle: glutathione amide reductase from chromatium gracile
64c3ab1B_



not modelled 100.0 21 PDB header:oxidoreductase
Chain: B: PDB Molecule:ferredoxin--nadp reductase;
PDBTitle: crystal structure of ferredoxin nadp+ oxidoreductase
65c3dgzA_



not modelled 100.0 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin reductase 2;
PDBTitle: crystal structure of mouse mitochondrial thioredoxin reductase, c-2 terminal 3-residue truncation
66c1zkqA_



not modelled 100.0 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin reductase 2, mitochondrial;
PDBTitle: crystal structure of mouse thioredoxin reductase type 2
67c1m6iA_



not modelled 100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:programmed cell death protein 8;
PDBTitle: crystal structure of apoptosis inducing factor (aif)
68c2a87A_



not modelled 100.0 27 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin reductase;
PDBTitle: crystal structure of m. tuberculosis thioredoxin reductase
69c3ctyA_



not modelled 100.0 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin reductase;
PDBTitle: crystal structure of t. acidophilum thioredoxin reductase
70c2w0hA_



not modelled 100.0 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:trypanothione reductase;
PDBTitle: x ray structure of leishmania infantum trypanothione2 reductase in complex with antimony and nadph
71c3d1cA_



not modelled 100.0 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:flavin-containing putative monooxygenase;
PDBTitle: crystal structure of flavin-containing putative monooxygenase2 (np_373108.1) from staphylococcus aureus mu50 at 2.40 a resolution
72c3hyxC_



not modelled 100.0 18 PDB header:oxidoreductase
Chain: C: PDB Molecule:sulfide-quinone reductase;
PDBTitle: 3-d x-ray structure of the sulfide:quinone oxidoreductase from aquifex2 aeolicus in complex with aurachin c
73c3kpgA_



not modelled 100.0 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:sulfide-quinone reductase, putative;
PDBTitle: crystal structure of sulfide:quinone oxidoreductase from2 acidithiobacillus ferrooxidans in complex with decylubiquinone
74c1lvlA_



not modelled 100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydrolipoamide dehydrogenase;
PDBTitle: the refined structure of pseudomonas putida lipoamide dehydrogenase2 complexed with nad+ at 2.45 angstroms resolution
75c2nvkX_



not modelled 100.0 20 PDB header:oxidoreductase
Chain: X: PDB Molecule:thioredoxin reductase;
PDBTitle: crystal structure of thioredoxin reductase from drosophila2 melanogaster
76c1fcdB_



not modelled 100.0 16 PDB header:electron transport(flavocytochrome)
Chain: B: PDB Molecule:flavocytochrome c sulfide dehydrogenase (flavin-
PDBTitle: the structure of flavocytochrome c sulfide dehydrogenase2 from a purple phototrophic bacterium chromatium vinosum at3 2.5 angstroms resolution
77c3cgdB_



not modelled 100.0 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:pyridine nucleotide-disulfide oxidoreductase, class i;
PDBTitle: pyridine nucleotide complexes with bacillus anthracis coenzyme a-2 disulfide reductase: a structural analysis of dual nad(p)h3 specificity
78c2q0lA_



not modelled 100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin reductase;
PDBTitle: helicobacter pylori thioredoxin reductase reduced by sodium dithionite2 in complex with nadp+
79c1fl2A_



not modelled 100.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:alkyl hydroperoxide reductase subunit f;
PDBTitle: catalytic core component of the alkylhydroperoxide reductase ahpf from2 e.coli
80c1ndaD_



not modelled 100.0 20 PDB header:oxidoreductase
Chain: D: PDB Molecule:trypanothione oxidoreductase;
PDBTitle: the structure of trypanosoma cruzi trypanothione reductase2 in the oxidized and nadph reduced state
81c2q7vA_



not modelled 99.9 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin reductase;
PDBTitle: crystal structure of deinococcus radiodurans thioredoxin2 reductase
82c3f8rD_



not modelled 99.9 18 PDB header:oxidoreductase
Chain: D: PDB Molecule:thioredoxin reductase (trxb-3);
PDBTitle: crystal structure of sulfolobus solfataricus thioredoxin2 reductase b3 in complex with two nadp molecules
83c3s5wB_



not modelled 99.9 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:l-ornithine 5-monooxygenase;
PDBTitle: ornithine hydroxylase (pvda) from pseudomonas aeruginosa
84c1onfA_



not modelled 99.9 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:glutathione reductase;
PDBTitle: crystal structure of plasmodium falciparum glutathione reductase
85c1y56A_



not modelled 99.9 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:hypothetical protein ph1363;
PDBTitle: crystal structure of l-proline dehydrogenase from p.horikoshii
86c1xhcA_



not modelled 99.9 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadh oxidase /nitrite reductase;
PDBTitle: nadh oxidase /nitrite reductase from pyrococcus furiosus pfu-1140779-2 001
87c2cfyB_



not modelled 99.9 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:thioredoxin reductase 1;
PDBTitle: crystal structure of human thioredoxin reductase 1
88c3fbsB_



not modelled 99.9 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:oxidoreductase;
PDBTitle: the crystal structure of the oxidoreductase from agrobacterium2 tumefaciens
89c3kljA_



not modelled 99.9 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:nad(fad)-dependent dehydrogenase, nirb-family (n-terminal
PDBTitle: crystal structure of nadh:rubredoxin oxidoreductase from clostridium2 acetobutylicum
90c3h8lA_



not modelled 99.9 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadh oxidase;
PDBTitle: the first x-ray structure of a sulfide:quinone2 oxidoreductase: insights into sulfide oxidation mechanism
91c2vq7B_



not modelled 99.9 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:flavin-containing monooxygenase;
PDBTitle: bacterial flavin-containing monooxygenase in complex with2 nadp: native data
92c1vqwB_



not modelled 99.9 22 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:protein with similarity to flavin-containing
PDBTitle: crystal structure of a protein with similarity to flavin-2 containing monooxygenases and to mammalian dimethylalanine3 monooxygenases
93c1w4xA_



not modelled 99.9 18 PDB header:oxygenase
Chain: A: PDB Molecule:phenylacetone monooxygenase;
PDBTitle: phenylacetone monooxygenase, a baeyer-villiger2 monooxygenase
94c3gwdA_



not modelled 99.9 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:cyclohexanone monooxygenase;
PDBTitle: closed crystal structure of cyclohexanone monooxygenase
95d1djqa3



not modelled 99.9 19 Fold:Nucleotide-binding domain
Superfamily:Nucleotide-binding domain
Family:N-terminal domain of adrenodoxin reductase-like
96d1cjca1



not modelled 99.9 29 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:C-terminal domain of adrenodoxin reductase-like
97d1ojta1



not modelled 99.9 23 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
98d1lqta1



not modelled 99.9 29 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:C-terminal domain of adrenodoxin reductase-like
99d1qo8a2



not modelled 99.8 19 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
100d1y0pa2



not modelled 99.8 24 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
101d3lada1



not modelled 99.8 28 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
102d1dxla1



not modelled 99.8 18 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
103d1gtea3



not modelled 99.8 28 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:C-terminal domain of adrenodoxin reductase-like
104d3grsa1



not modelled 99.8 24 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
105c2bryA_



not modelled 99.8 16 PDB header:transport
Chain: A: PDB Molecule:nedd9 interacting protein with calponin homology
PDBTitle: crystal structure of the native monooxygenase domain of2 mical at 1.45 a resolution
106d1mo9a1



not modelled 99.8 28 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
107d1d4ca2



not modelled 99.8 29 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
108d1lpfa1



not modelled 99.8 25 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
109d1seza1



not modelled 99.8 17 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD-linked reductases, N-terminal domain
110d1ps9a3



not modelled 99.8 30 Fold:Nucleotide-binding domain
Superfamily:Nucleotide-binding domain
Family:N-terminal domain of adrenodoxin reductase-like
111d1ebda1



not modelled 99.8 20 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
112d1reoa1



not modelled 99.8 16 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD-linked reductases, N-terminal domain
113d1feca1



not modelled 99.8 18 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
114d1h6va1



not modelled 99.8 20 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
115d2bs2a2



not modelled 99.8 18 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
116d1v59a1



not modelled 99.8 20 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
117d1kf6a2



not modelled 99.8 20 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
118d1lvla1



not modelled 99.8 21 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
119d1lqta2



not modelled 99.8 18 Fold:Nucleotide-binding domain
Superfamily:Nucleotide-binding domain
Family:N-terminal domain of adrenodoxin reductase-like
120d2iida1



not modelled 99.7 16 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD-linked reductases, N-terminal domain

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0