Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	E	K	L	Q	K	V	L	A	R	A	G	H	G	S	R	R	E	I	E	S	I	I	E	A	G	R	V	S	V	D	G	K	I	A	K	L	G	D	R	V	E	V	T	P	G	L	K	I	R	I	D	G	H	L	I	S	V	R
Secondary structure
SS confidence
Disorder		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		E	S	A	E	Q	I	C	R	V	L	A	Y	Y	K	P	E	G	E	L	C	T	R	N	D	P	E	G	R	P	T	V	F	D	R	L	P	K	L	R	G	A	R	W	I	A	V	G	R	L	D	V	N	T	C	G	L	L	L	F	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		T	D	G	E	L	A	N	R	L	M	H	P	S	R	E	V	E	R	E	Y	A	V	R	V	F	G	Q	V	D	D	A	K	L	R	D	L	S	R	G	V	Q	L	E	D	G	P	A	A	F	K	T	I	K	F	S	G	G	E	G	I
Secondary structure
SS confidence
Disorder													?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		N	Q	W	Y	N	V	T	L	T	E	G	R	N	R	E	V	R	R	L	W	E	A	V	G	V	Q	V	S	R	L	I	R	V	R	Y	G	D	I	P	L	P	K	G	L	P	R	G	G	W	T	E	L	D	L	A	Q	T	N	Y	L
Secondary structure
SS confidence
Disorder																																										?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.
Sequence		R	E	L	V	E	L	P	P	E	T	S	S	K	V	A	V	E	K	D	R	R	R	M	K	A	N	Q	I	R	R	A	V	K	R	H	S	Q	V	S	G	G	R	R	S	G	G	R	N	N	N	G
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3dh3 chain C Region: 3 - 250 Aligned: 236 Modelled: 248 Confidence: 100.0% Identity: 31% PDB header:isomerase/rna Chain: C: PDB Molecule:ribosomal large subunit pseudouridine synthase f; PDBTitle: crystal structure of rluf in complex with a 22 nucleotide2 rna substrate Phyre2 PDB 1vio chain A Region: 2 - 240 Aligned: 227 Modelled: 239 Confidence: 100.0% Identity: 26% PDB header:lyase Chain: A: PDB Molecule:ribosomal small subunit pseudouridine synthase a; PDBTitle: crystal structure of pseudouridylate synthase Phyre2 PDB 1ksk chain A Region: 4 - 240 Aligned: 226 Modelled: 237 Confidence: 100.0% Identity: 30% PDB header:lyase Chain: A: PDB Molecule:ribosomal small subunit pseudouridine synthase a; PDBTitle: structure of rsua Phyre2 PDB 1vio chain A domain 1 Region: 65 - 240 Aligned: 171 Modelled: 176 Confidence: 100.0% Identity: 28% Fold: Pseudouridine synthase Superfamily: Pseudouridine synthase Family: Pseudouridine synthase RsuA/RluD Phyre2 PDB 1ksk chain A domain 4 Region: 67 - 240 Aligned: 171 Modelled: 174 Confidence: 100.0% Identity: 32% Fold: Pseudouridine synthase Superfamily: Pseudouridine synthase Family: Pseudouridine synthase RsuA/RluD Phyre2 PDB 2gml chain A Region: 66 - 245 Aligned: 172 Modelled: 180 Confidence: 100.0% Identity: 30% PDB header:isomerase Chain: A: PDB Molecule:ribosomal large subunit pseudouridine synthase f; PDBTitle: crystal structure of catalytic domain of e.coli rluf Phyre2 PDB 2oml chain A Region: 65 - 234 Aligned: 166 Modelled: 170 Confidence: 100.0% Identity: 37% PDB header:isomerase Chain: A: PDB Molecule:ribosomal large subunit pseudouridine synthase e; PDBTitle: crystal structure of e. coli pseudouridine synthase rlue Phyre2 PDB 2olw chain B Region: 66 - 234 Aligned: 165 Modelled: 169 Confidence: 100.0% Identity: 36% PDB header:isomerase Chain: B: PDB Molecule:ribosomal large subunit pseudouridine synthase e; PDBTitle: crystal structure of e. coli pseudouridine synthase rlue Phyre2 PDB 1v9f chain A Region: 61 - 208 Aligned: 148 Modelled: 148 Confidence: 100.0% Identity: 19% Fold: Pseudouridine synthase Superfamily: Pseudouridine synthase Family: Pseudouridine synthase RsuA/RluD Phyre2 PDB 1v9f chain A Region: 61 - 208 Aligned: 148 Modelled: 148 Confidence: 100.0% Identity: 19% PDB header:lyase Chain: A: PDB Molecule:ribosomal large subunit pseudouridine synthase d; PDBTitle: crystal structure of catalytic domain of pseudouridine2 synthase rlud from escherichia coli Phyre2 PDB 2i82 chain D Region: 52 - 208 Aligned: 157 Modelled: 156 Confidence: 100.0% Identity: 20% PDB header:lyase/rna Chain: D: PDB Molecule:ribosomal large subunit pseudouridine synthase a; PDBTitle: crystal structure of pseudouridine synthase rlua: indirect2 sequence readout through protein-induced rna structure Phyre2 PDB 1v9k chain A Region: 60 - 208 Aligned: 149 Modelled: 149 Confidence: 100.0% Identity: 17% Fold: Pseudouridine synthase Superfamily: Pseudouridine synthase Family: Pseudouridine synthase RsuA/RluD Phyre2 PDB 1qyu chain A Region: 55 - 208 Aligned: 154 Modelled: 153 Confidence: 100.0% Identity: 18% PDB header:lyase Chain: A: PDB Molecule:ribosomal large subunit pseudouridine synthase d; PDBTitle: structure of the catalytic domain of 23s rrna pseudouridine2 synthase rlud Phyre2 PDB 1vio chain A domain 2 Region: 2 - 59 Aligned: 57 Modelled: 58 Confidence: 99.1% Identity: 25% Fold: Alpha-L RNA-binding motif Superfamily: Alpha-L RNA-binding motif Family: Pseudouridine synthase RsuA N-terminal domain Phyre2 PDB 2ey4 chain A domain 2 Region: 69 - 243 Aligned: 154 Modelled: 167 Confidence: 99.0% Identity: 23% Fold: Pseudouridine synthase Superfamily: Pseudouridine synthase Family: Pseudouridine synthase II TruB Phyre2 PDB 2apo chain A domain 2 Region: 69 - 225 Aligned: 145 Modelled: 157 Confidence: 99.0% Identity: 17% Fold: Pseudouridine synthase Superfamily: Pseudouridine synthase Family: Pseudouridine synthase II TruB Phyre2 PDB 2k6p chain A Region: 3 - 76 Aligned: 74 Modelled: 74 Confidence: 99.0% Identity: 15% PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein hp_1423; PDBTitle: solution structure of hypothetical protein, hp1423 Phyre2 PDB 1dm9 chain A Region: 2 - 57 Aligned: 56 Modelled: 56 Confidence: 98.9% Identity: 27% PDB header:structural genomics Chain: A: PDB Molecule:hypothetical 15.5 kd protein in mrca-pcka PDBTitle: heat shock protein 15 kd Phyre2 PDB 1dm9 chain A Region: 2 - 57 Aligned: 56 Modelled: 56 Confidence: 98.9% Identity: 27% Fold: Alpha-L RNA-binding motif Superfamily: Alpha-L RNA-binding motif Family: Heat shock protein 15 kD Phyre2 PDB 1p9k chain A Region: 4 - 57 Aligned: 53 Modelled: 54 Confidence: 98.9% Identity: 26% Fold: Alpha-L RNA-binding motif Superfamily: Alpha-L RNA-binding motif Family: YbcJ-like Phyre2 1 c3dh3C_ 2 c1vioA_ 3 c1kskA_ 4 d1vioa1 5 d1kska4 6 c2gmlA_ 7 c2omlA_ 8 c2olwB_ 9 d1v9fa_ 10 c1v9fA_ 11 c2i82D_ 12 d1v9ka_ 13 c1qyuA_ 14 d1vioa2 15 d2ey4a2 16 d2apoa2 17 c2k6pA_ 18 c1dm9A_ 19 d1dm9a_ 20 d1p9ka_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3dh3C_ 100.0 31 PDB header:isomerase/rna Chain: C: PDB Molecule:ribosomal large subunit pseudouridine synthase f; PDBTitle: crystal structure of rluf in complex with a 22 nucleotide2 rna substrate 2 c1vioA_ 100.0 26 PDB header:lyase Chain: A: PDB Molecule:ribosomal small subunit pseudouridine synthase a; PDBTitle: crystal structure of pseudouridylate synthase 3 c1kskA_ 100.0 30 PDB header:lyase Chain: A: PDB Molecule:ribosomal small subunit pseudouridine synthase a; PDBTitle: structure of rsua 4 d1vioa1 100.0 28 Fold:Pseudouridine synthase Superfamily:Pseudouridine synthase Family:Pseudouridine synthase RsuA/RluD 5 d1kska4 100.0 32 Fold:Pseudouridine synthase Superfamily:Pseudouridine synthase Family:Pseudouridine synthase RsuA/RluD 6 c2gmlA_ 100.0 30 PDB header:isomerase Chain: A: PDB Molecule:ribosomal large subunit pseudouridine synthase f; PDBTitle: crystal structure of catalytic domain of e.coli rluf 7 c2omlA_ 100.0 37 PDB header:isomerase Chain: A: PDB Molecule:ribosomal large subunit pseudouridine synthase e; PDBTitle: crystal structure of e. coli pseudouridine synthase rlue 8 c2olwB_ 100.0 36 PDB header:isomerase Chain: B: PDB Molecule:ribosomal large subunit pseudouridine synthase e; PDBTitle: crystal structure of e. coli pseudouridine synthase rlue 9 d1v9fa_ 100.0 19 Fold:Pseudouridine synthase Superfamily:Pseudouridine synthase Family:Pseudouridine synthase RsuA/RluD 10 c1v9fA_ 100.0 19 PDB header:lyase Chain: A: PDB Molecule:ribosomal large subunit pseudouridine synthase d; PDBTitle: crystal structure of catalytic domain of pseudouridine2 synthase rlud from escherichia coli 11 c2i82D_ 100.0 20 PDB header:lyase/rna Chain: D: PDB Molecule:ribosomal large subunit pseudouridine synthase a; PDBTitle: crystal structure of pseudouridine synthase rlua: indirect2 sequence readout through protein-induced rna structure 12 d1v9ka_ 100.0 17 Fold:Pseudouridine synthase Superfamily:Pseudouridine synthase Family:Pseudouridine synthase RsuA/RluD 13 c1qyuA_ 100.0 18 PDB header:lyase Chain: A: PDB Molecule:ribosomal large subunit pseudouridine synthase d; PDBTitle: structure of the catalytic domain of 23s rrna pseudouridine2 synthase rlud 14 d1vioa2 99.1 25 Fold:Alpha-L RNA-binding motif Superfamily:Alpha-L RNA-binding motif Family:Pseudouridine synthase RsuA N-terminal domain 15 d2ey4a2 99.0 23 Fold:Pseudouridine synthase Superfamily:Pseudouridine synthase Family:Pseudouridine synthase II TruB 16 d2apoa2 99.0 17 Fold:Pseudouridine synthase Superfamily:Pseudouridine synthase Family:Pseudouridine synthase II TruB 17 c2k6pA_ 99.0 15 PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein hp_1423; PDBTitle: solution structure of hypothetical protein, hp1423 18 c1dm9A_ 98.9 27 PDB header:structural genomics Chain: A: PDB Molecule:hypothetical 15.5 kd protein in mrca-pcka PDBTitle: heat shock protein 15 kd 19 d1dm9a_ 98.9 27 Fold:Alpha-L RNA-binding motif Superfamily:Alpha-L RNA-binding motif Family:Heat shock protein 15 kD 20 d1p9ka_ 98.9 26 Fold:Alpha-L RNA-binding motif Superfamily:Alpha-L RNA-binding motif Family:YbcJ-like 21 c3bbnD_ not modelled 98.9 16 PDB header:ribosome Chain: D: PDB Molecule:ribosomal protein s4; PDBTitle: homology model for the spinach chloroplast 30s subunit2 fitted to 9.4a cryo-em map of the 70s chlororibosome. 22 d1r3ea2 not modelled 98.9 23 Fold:Pseudouridine synthase Superfamily:Pseudouridine synthase Family:Pseudouridine synthase II TruB 23 c2cqjA_ not modelled 98.9 20 PDB header:rna binding protein Chain: A: PDB Molecule:u3 small nucleolar ribonucleoprotein protein PDBTitle: solution structure of the s4 domain of u3 small nucleolar2 ribonucleoprotein protein imp3 homolog 24 c2ey4A_ not modelled 98.8 23 PDB header:isomerase/biosynthetic protein Chain: A: PDB Molecule:probable trna pseudouridine synthase b; PDBTitle: crystal structure of a cbf5-nop10-gar1 complex 25 d1k8wa5 not modelled 98.8 23 Fold:Pseudouridine synthase Superfamily:Pseudouridine synthase Family:Pseudouridine synthase II TruB 26 c2apoA_ not modelled 98.8 16 PDB header:isomerase/rna binding protein Chain: A: PDB Molecule:probable trna pseudouridine synthase b; PDBTitle: crystal structure of the methanococcus jannaschii cbf52 nop10 complex 27 d1c06a_ not modelled 98.7 20 Fold:Alpha-L RNA-binding motif Superfamily:Alpha-L RNA-binding motif Family:Ribosomal protein S4 28 c1k8wA_ not modelled 98.5 23 PDB header:lyase/rna Chain: A: PDB Molecule:trna pseudouridine synthase b; PDBTitle: crystal structure of the e. coli pseudouridine synthase2 trub bound to a t stem-loop rna 29 d2uubd1 not modelled 98.5 28 Fold:Alpha-L RNA-binding motif Superfamily:Alpha-L RNA-binding motif Family:Ribosomal protein S4 30 c1sgvA_ not modelled 98.4 19 PDB header:lyase Chain: A: PDB Molecule:trna pseudouridine synthase b; PDBTitle: structure of trna psi55 pseudouridine synthase (trub) 31 d1sgva2 not modelled 98.4 19 Fold:Pseudouridine synthase Superfamily:Pseudouridine synthase Family:Pseudouridine synthase II TruB 32 c3uaiA_ not modelled 98.4 19 PDB header:isomerase/chaperone Chain: A: PDB Molecule:h/aca ribonucleoprotein complex subunit 4; PDBTitle: structure of the shq1-cbf5-nop10-gar1 complex from saccharomyces2 cerevisiae 33 d2gy9d1 not modelled 98.3 22 Fold:Alpha-L RNA-binding motif Superfamily:Alpha-L RNA-binding motif Family:Ribosomal protein S4 34 c3hp7A_ not modelled 97.9 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hemolysin, putative; PDBTitle: putative hemolysin from streptococcus thermophilus. 35 d1kska3 not modelled 97.7 28 Fold:Alpha-L RNA-binding motif Superfamily:Alpha-L RNA-binding motif Family:Pseudouridine synthase RsuA N-terminal domain 36 c1s1hD_ not modelled 97.6 16 PDB header:ribosome Chain: D: PDB Molecule:40s ribosomal protein s9-a; PDBTitle: structure of the ribosomal 80s-eef2-sordarin complex from2 yeast obtained by docking atomic models for rna and protein3 components into a 11.7 a cryo-em map. this file, 1s1h,4 contains 40s subunit. the 60s ribosomal subunit is in file5 1s1i. 37 c2xzmD_ not modelled 97.6 15 PDB header:ribosome Chain: D: PDB Molecule:ribosomal protein s4 containing protein; PDBTitle: crystal structure of the eukaryotic 40s ribosomal2 subunit in complex with initiation factor 1. this file3 contains the 40s subunit and initiation factor for4 molecule 1 38 c1ze2B_ not modelled 96.7 22 PDB header:lyase/rna Chain: B: PDB Molecule:trna pseudouridine synthase b; PDBTitle: conformational change of pseudouridine 55 synthase upon its2 association with rna substrate 39 d1h3fa2 not modelled 96.7 17 Fold:Alpha-L RNA-binding motif Superfamily:Alpha-L RNA-binding motif Family:Tyrosyl-tRNA synthetase (TyrRS), C-terminal domain 40 d1jh3a_ not modelled 96.3 28 Fold:Alpha-L RNA-binding motif Superfamily:Alpha-L RNA-binding motif Family:Tyrosyl-tRNA synthetase (TyrRS), C-terminal domain 41 c1h3eA_ not modelled 96.1 18 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: tyrosyl-trna synthetase from thermus thermophilus complexed2 with wild-type trnatyr(gua) and with atp and tyrosinol 42 c2janD_ not modelled 95.3 22 PDB header:ligase Chain: D: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: tyrosyl-trna synthetase from mycobacterium tuberculosis in2 unliganded state 43 c3kbgA_ not modelled 93.6 35 PDB header:ribosomal protein Chain: A: PDB Molecule:30s ribosomal protein s4e; PDBTitle: crystal structure of the 30s ribosomal protein s4e from2 thermoplasma acidophilum. northeast structural genomics3 consortium target tar28. 44 c3iz6C_ not modelled 92.8 20 PDB header:ribosome Chain: C: PDB Molecule:40s ribosomal protein s9 (s4p); PDBTitle: localization of the small subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome 45 c3izbD_ not modelled 91.0 23 PDB header:ribosome Chain: D: PDB Molecule:40s ribosomal protein rps4 (s4e); PDBTitle: localization of the small subunit ribosomal proteins into a 6.1 a2 cryo-em map of saccharomyces cerevisiae translating 80s ribosome 46 c3iz6D_ not modelled 91.0 26 PDB header:ribosome Chain: D: PDB Molecule:40s ribosomal protein s4 (s4e); PDBTitle: localization of the small subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome 47 c2xzmW_ not modelled 90.9 22 PDB header:ribosome Chain: W: PDB Molecule:40s ribosomal protein s4; PDBTitle: crystal structure of the eukaryotic 40s ribosomal2 subunit in complex with initiation factor 1. this file3 contains the 40s subunit and initiation factor for4 molecule 1 48 d2hzaa1 not modelled 65.9 31 Fold:Ribbon-helix-helix Superfamily:Ribbon-helix-helix Family:CopG-like 49 d2hzab1 not modelled 64.6 31 Fold:Ribbon-helix-helix Superfamily:Ribbon-helix-helix Family:CopG-like 50 c1q5vB_ not modelled 50.3 31 PDB header:transcription Chain: B: PDB Molecule:nickel responsive regulator; PDBTitle: apo-nikr 51 d2bj7a1 not modelled 48.4 29 Fold:Ribbon-helix-helix Superfamily:Ribbon-helix-helix Family:CopG-like 52 c3h7hA_ not modelled 47.7 20 PDB header:transcription Chain: A: PDB Molecule:transcription elongation factor spt4; PDBTitle: crystal structure of the human transcription elongation factor dsif,2 hspt4/hspt5 (176-273) 53 c2bj3D_ not modelled 47.3 29 PDB header:transcription Chain: D: PDB Molecule:nickel responsive regulator; PDBTitle: nikr-apo 54 c2exuA_ not modelled 40.3 20 PDB header:transcription Chain: A: PDB Molecule:transcription initiation protein spt4/spt5; PDBTitle: crystal structure of saccharomyces cerevisiae transcription elongation2 factors spt4-spt5ngn domain 55 d1d4ta_ not modelled 32.1 18 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 56 c2ca9B_ not modelled 30.9 23 PDB header:transcriptional regulation Chain: B: PDB Molecule:putative nickel-responsive regulator; PDBTitle: apo-nikr from helicobacter pylori in closed trans-2 conformation 57 c2ktlA_ not modelled 24.6 32 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: structure of c-terminal domain from mttyrrs of a. nidulans 58 d1f2fa_ not modelled 20.4 11 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 59 d2g1la1 not modelled 18.2 12 Fold:SMAD/FHA domain Superfamily:SMAD/FHA domain Family:FHA domain 60 c3iz5w_ not modelled 17.9 33 PDB header:ribosome Chain: W: PDB Molecule:60s ribosomal protein l22 (l22e); PDBTitle: localization of the large subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome 61 d1rwsa_ not modelled 17.3 23 Fold:beta-Grasp (ubiquitin-like) Superfamily:MoaD/ThiS Family:ThiS 62 c2r9qD_ not modelled 16.6 9 PDB header:hydrolase Chain: D: PDB Molecule:2'-deoxycytidine 5'-triphosphate deaminase; PDBTitle: crystal structure of 2'-deoxycytidine 5'-triphosphate deaminase from2 agrobacterium tumefaciens 63 c2kmmA_ not modelled 16.4 14 PDB header:hydrolase Chain: A: PDB Molecule:guanosine-3',5'-bis(diphosphate) 3'- PDBTitle: solution nmr structure of the tgs domain of pg1808 from2 porphyromonas gingivalis. northeast structural genomics3 consortium target pgr122a (418-481) 64 c3hvzB_ not modelled 15.6 23 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of the tgs domain of the clolep_03100 protein from2 clostridium leptum, northeast structural genomics consortium target3 qlr13a 65 d1o48a_ not modelled 15.5 11 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 66 d1i3za_ not modelled 15.0 22 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 67 d2cu3a1 not modelled 13.9 18 Fold:beta-Grasp (ubiquitin-like) Superfamily:MoaD/ThiS Family:ThiS 68 c1yj5C_ not modelled 12.6 17 PDB header:transferase Chain: C: PDB Molecule:5' polynucleotide kinase-3' phosphatase fha domain; PDBTitle: molecular architecture of mammalian polynucleotide kinase, a dna2 repair enzyme 69 d1tq5a1 not modelled 11.4 24 Fold:Double-stranded beta-helix Superfamily:RmlC-like cupins Family:Pirin-like 70 d1nyra2 not modelled 11.1 18 Fold:beta-Grasp (ubiquitin-like) Superfamily:TGS-like Family:TGS domain 71 c1gxcA_ not modelled 10.9 15 PDB header:phosphoprotein-binding domain Chain: A: PDB Molecule:serine/threonine-protein kinase chk2; PDBTitle: fha domain from human chk2 kinase in complex with a2 synthetic phosphopeptide 72 d1gxca_ not modelled 10.9 15 Fold:SMAD/FHA domain Superfamily:SMAD/FHA domain Family:FHA domain 73 d1tkea1 not modelled 10.8 26 Fold:beta-Grasp (ubiquitin-like) Superfamily:TGS-like Family:TGS domain 74 c3po0A_ not modelled 10.3 25 PDB header:protein binding Chain: A: PDB Molecule:small archaeal modifier protein 1; PDBTitle: crystal structure of samp1 from haloferax volcanii 75 c3izcw_ not modelled 10.2 30 PDB header:ribosome Chain: W: PDB Molecule:60s ribosomal protein rpl22 (l22e); PDBTitle: localization of the large subunit ribosomal proteins into a 6.1 a2 cryo-em map of saccharomyces cerevisiae translating 80s ribosome 76 d1fm0d_ not modelled 10.2 9 Fold:beta-Grasp (ubiquitin-like) Superfamily:MoaD/ThiS Family:MoaD 77 c3mazA_ not modelled 10.0 16 PDB header:signaling protein Chain: A: PDB Molecule:signal-transducing adaptor protein 1; PDBTitle: crystal structure of the human brdg1/stap-1 sh2 domain in complex with2 the ntal ptyr136 peptide 78 c3kt9A_ not modelled 9.4 21 PDB header:hydrolase Chain: A: PDB Molecule:aprataxin; PDBTitle: aprataxin fha domain 79 d1fhsa_ not modelled 9.3 13 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 80 d1g6ga_ not modelled 9.1 13 Fold:SMAD/FHA domain Superfamily:SMAD/FHA domain Family:FHA domain 81 d1rpya_ not modelled 9.1 27 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 82 c1ka6A_ not modelled 9.0 17 PDB header:immune system Chain: A: PDB Molecule:sh2 domain protein 1a; PDBTitle: sap/sh2d1a bound to peptide n-py 83 c1t6sB_ not modelled 9.0 22 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:conserved hypothetical protein; PDBTitle: crystal structure of a conserved hypothetical protein from chlorobium2 tepidum 84 c2eh0A_ not modelled 9.0 12 PDB header:transport protein Chain: A: PDB Molecule:kinesin-like protein kif1b; PDBTitle: solution structure of the fha domain from human kinesin-2 like protein kif1b 85 d1lgpa_ not modelled 9.0 7 Fold:SMAD/FHA domain Superfamily:SMAD/FHA domain Family:FHA domain 86 c1mzwB_ not modelled 8.9 31 PDB header:isomerase Chain: B: PDB Molecule:u4/u6 snrnp 60kda protein; PDBTitle: crystal structure of a u4/u6 snrnp complex between human2 spliceosomal cyclophilin h and a u4/u6-60k peptide 87 c2gsbA_ not modelled 8.5 11 PDB header:signaling protein Chain: A: PDB Molecule:ras gtpase-activating protein 1; PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1 88 d1qcfa2 not modelled 8.3 10 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 89 d1vjka_ not modelled 8.2 8 Fold:beta-Grasp (ubiquitin-like) Superfamily:MoaD/ThiS Family:MoaD 90 d1t6sa2 not modelled 8.1 22 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:ScpB/YpuH-like 91 c2w1oA_ not modelled 8.1 29 PDB header:translation Chain: A: PDB Molecule:60s acidic ribosomal protein p2; PDBTitle: nmr structure of dimerization domain of human ribosomal2 protein p2 92 d1g3ga_ not modelled 8.0 13 Fold:SMAD/FHA domain Superfamily:SMAD/FHA domain Family:FHA domain 93 c3b4sA_ not modelled 7.5 29 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:protein luxt; PDBTitle: crystal structure of a luxt domain from vibrio2 parahaemolyticus rimd 2210633 94 c2qieB_ not modelled 7.5 13 PDB header:transferase Chain: B: PDB Molecule:molybdopterin synthase small subunit; PDBTitle: staphylococcus aureus molybdopterin synthase in complex2 with precursor z 95 c2el8A_ not modelled 7.4 9 PDB header:signaling protein Chain: A: PDB Molecule:signal-transducing adaptor protein 2; PDBTitle: solution structure of the human stap2 sh2 domain 96 c2ysxA_ not modelled 7.1 9 PDB header:signaling protein Chain: A: PDB Molecule:signaling inositol polyphosphate phosphatase PDBTitle: solution structure of the human ship sh2 domain 97 d2exda1 not modelled 7.0 25 Fold:OB-fold Superfamily:NfeD domain-like Family:NfeD domain-like 98 c2k5hA_ not modelled 7.0 33 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved protein; PDBTitle: solution nmr structure of protein encoded by mth693 from2 methanobacterium thermoautotrophicum: northeast structural3 genomics consortium target tt824a 99 d1opka2 not modelled 7.0 14 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0