Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	L	N	T	P	Q	I	T	P	T	K	K	I	T	V	R	A	I	G	E	E	L	P	R	G	D	Y	Q	R	C	P	Q	C	D	M	L	F	S	L	P	E	I	N	S	H	Q	S	A	Y	C	P	R	C	Q	A	K	I	R	D
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?			?																		?	?	?	?														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	R	D	W	S	L	T	R	L	A	A	M	A	F	T	M	L	L	L	M	P	F	A	W	G	E	P	L	L	H	I	W	L	L	G	I	R	I	D	A	N	V	M	Q	G	I	W	Q	M	T	K	Q	G	D	A	I	T	G	S	M
Secondary structure
SS confidence
Disorder		?																														?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	F	F	C	V	I	G	A	P	L	I	L	V	T	S	I	A	Y	L	W	F	G	N	R	L	G	M	N	L	R	P	V	L	L	M	L	E	R	L	K	E	W	V	M	L	D	I	Y	L	V	G	I	G	V	A	S	I	K	V	Q
Secondary structure
SS confidence
Disorder																								?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		D	Y	A	H	I	Q	A	G	V	G	L	F	S	F	V	A	L	V	I	L	T	T	V	T	L	S	H	L	N	V	E	E	L	W	E	R	F	Y	P	Q	R	P	A	T	R	R	D	E	K	L	R	V	C	L	G	C	H	F	T	G
Secondary structure
SS confidence
Disorder			?	?	?																																				?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		Y	P	D	Q	R	G	R	C	P	R	C	H	I	P	L	R	L	R	R	R	H	S	L	Q	K	C	W	A	A	L	L	A	S	I	V	L	L	L	P	A	N	L	L	P	I	S	I	I	Y	L	N	G	G	R	Q	E	D	T	I	L
Secondary structure
SS confidence
Disorder																			?																																	?	?	?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		S	G	I	M	S	L	A	S	S	N	I	A	V	A	G	I	V	F	I	A	S	I	L	V	P	F	T	K	V	I	V	M	F	T	L	L	L	S	I	H	F	K	C	Q	Q	G	L	R	T	R	I	L	L	L	R	M	V	T	W	I
Secondary structure
SS confidence
Disorder																																										?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		G	R	W	S	M	L	D	L	F	V	I	S	L	T	M	S	L	I	N	R	D	Q	I	L	A	F	T	M	G	P	A	A	F	Y	F	G	A	A	V	I	L	T	I	L	A	V	E	W	L	D	S	R	L	L	W	D	A	H	E	S
Secondary structure
SS confidence
Disorder																										?																																			?
Disorder confidence
		.	.	.	.	.	.	.
Sequence		G	N	A	R	F	D	D
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2ppt chain A Region: 20 - 67 Aligned: 48 Modelled: 48 Confidence: 94.6% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin-2; PDBTitle: crystal structure of thioredoxin-2 Phyre2 PDB 2lcq chain A Region: 29 - 64 Aligned: 32 Modelled: 36 Confidence: 92.8% Identity: 25% PDB header:metal binding protein Chain: A: PDB Molecule:putative toxin vapc6; PDBTitle: solution structure of the endonuclease nob1 from p.horikoshii Phyre2 PDB 2hr5 chain B Region: 20 - 57 Aligned: 33 Modelled: 38 Confidence: 92.0% Identity: 30% PDB header:metal binding protein Chain: B: PDB Molecule:rubrerythrin; PDBTitle: pf1283- rubrerythrin from pyrococcus furiosus iron bound form Phyre2 PDB 1dl6 chain A Region: 22 - 61 Aligned: 39 Modelled: 40 Confidence: 91.1% Identity: 18% Fold: Rubredoxin-like Superfamily: Zinc beta-ribbon Family: Transcriptional factor domain Phyre2 PDB 2f9i chain D Region: 28 - 70 Aligned: 42 Modelled: 43 Confidence: 90.8% Identity: 17% PDB header:transferase Chain: D: PDB Molecule:acetyl-coenzyme a carboxylase carboxyl PDBTitle: crystal structure of the carboxyltransferase subunit of acc2 from staphylococcus aureus Phyre2 PDB 1aky chain A domain 2 Region: 28 - 64 Aligned: 37 Modelled: 37 Confidence: 90.5% Identity: 5% Fold: Rubredoxin-like Superfamily: Microbial and mitochondrial ADK, insert "zinc finger" domain Family: Microbial and mitochondrial ADK, insert "zinc finger" domain Phyre2 PDB 2ak3 chain A domain 2 Region: 28 - 63 Aligned: 36 Modelled: 36 Confidence: 89.8% Identity: 6% Fold: Rubredoxin-like Superfamily: Microbial and mitochondrial ADK, insert "zinc finger" domain Family: Microbial and mitochondrial ADK, insert "zinc finger" domain Phyre2 PDB 1p3j chain A domain 2 Region: 28 - 61 Aligned: 34 Modelled: 34 Confidence: 89.4% Identity: 12% Fold: Rubredoxin-like Superfamily: Microbial and mitochondrial ADK, insert "zinc finger" domain Family: Microbial and mitochondrial ADK, insert "zinc finger" domain Phyre2 PDB 2f9y chain B domain 1 Region: 28 - 72 Aligned: 41 Modelled: 45 Confidence: 89.1% Identity: 22% Fold: ClpP/crotonase Superfamily: ClpP/crotonase Family: Biotin dependent carboxylase carboxyltransferase domain Phyre2 PDB 2f9y chain B Region: 28 - 72 Aligned: 41 Modelled: 45 Confidence: 89.1% Identity: 22% PDB header:ligase Chain: B: PDB Molecule:acetyl-coenzyme a carboxylase carboxyl transferase subunit PDBTitle: the crystal structure of the carboxyltransferase subunit of acc from2 escherichia coli Phyre2 PDB 1zin chain A domain 2 Region: 28 - 61 Aligned: 34 Modelled: 34 Confidence: 88.9% Identity: 15% Fold: Rubredoxin-like Superfamily: Microbial and mitochondrial ADK, insert "zinc finger" domain Family: Microbial and mitochondrial ADK, insert "zinc finger" domain Phyre2 PDB 1s3g chain A domain 2 Region: 28 - 61 Aligned: 34 Modelled: 34 Confidence: 88.8% Identity: 12% Fold: Rubredoxin-like Superfamily: Microbial and mitochondrial ADK, insert "zinc finger" domain Family: Microbial and mitochondrial ADK, insert "zinc finger" domain Phyre2 PDB 1dvb chain A Region: 26 - 57 Aligned: 27 Modelled: 32 Confidence: 87.6% Identity: 22% PDB header:electron transport Chain: A: PDB Molecule:rubrerythrin; PDBTitle: rubrerythrin Phyre2 PDB 1k3x chain A domain 3 Region: 31 - 56 Aligned: 26 Modelled: 26 Confidence: 87.4% Identity: 27% Fold: Glucocorticoid receptor-like (DNA-binding domain) Superfamily: Glucocorticoid receptor-like (DNA-binding domain) Family: C-terminal, Zn-finger domain of MutM-like DNA repair proteins Phyre2 PDB 1yc5 chain A domain 1 Region: 27 - 59 Aligned: 33 Modelled: 33 Confidence: 87.3% Identity: 24% Fold: DHS-like NAD/FAD-binding domain Superfamily: DHS-like NAD/FAD-binding domain Family: Sir2 family of transcriptional regulators Phyre2 PDB 1e4v chain A domain 2 Region: 28 - 61 Aligned: 34 Modelled: 34 Confidence: 86.7% Identity: 0% Fold: Rubredoxin-like Superfamily: Microbial and mitochondrial ADK, insert "zinc finger" domain Family: Microbial and mitochondrial ADK, insert "zinc finger" domain Phyre2 PDB 1hk8 chain A Region: 27 - 57 Aligned: 29 Modelled: 31 Confidence: 86.4% Identity: 14% PDB header:oxidoreductase Chain: A: PDB Molecule:anaerobic ribonucleotide-triphosphate reductase; PDBTitle: structural basis for allosteric substrate specificity2 regulation in class iii ribonucleotide reductases:3 nrdd in complex with dgtp Phyre2 PDB 1hk8 chain A Region: 27 - 57 Aligned: 29 Modelled: 31 Confidence: 86.4% Identity: 14% Fold: PFL-like glycyl radical enzymes Superfamily: PFL-like glycyl radical enzymes Family: Class III anaerobic ribonucleotide reductase NRDD subunit Phyre2 PDB 2gb5 chain B Region: 31 - 61 Aligned: 29 Modelled: 31 Confidence: 86.0% Identity: 14% PDB header:hydrolase Chain: B: PDB Molecule:nadh pyrophosphatase; PDBTitle: crystal structure of nadh pyrophosphatase (ec 3.6.1.22) (1790429) from2 escherichia coli k12 at 2.30 a resolution Phyre2 PDB 2gnr chain A domain 1 Region: 28 - 57 Aligned: 24 Modelled: 30 Confidence: 86.0% Identity: 29% Fold: OB-fold Superfamily: Nucleic acid-binding proteins Family: SSO2064-like Phyre2 PDB 2con chain A domain 1 Region: 230 - 254 Aligned: 25 Modelled: 25 Confidence: 68.0% Identity: 28% Fold: Rubredoxin-like Superfamily: NOB1 zinc finger-like Family: NOB1 zinc finger-like Phyre2 PDB 2odx chain A Region: 218 - 253 Aligned: 36 Modelled: 36 Confidence: 67.8% Identity: 19% PDB header:oxidoreductase Chain: A: PDB Molecule:cytochrome c oxidase polypeptide iv; PDBTitle: solution structure of zn(ii)cox4 Phyre2 PDB 1yuz chain B Region: 233 - 254 Aligned: 22 Modelled: 22 Confidence: 66.8% Identity: 27% PDB header:oxidoreductase Chain: B: PDB Molecule:nigerythrin; PDBTitle: partially reduced state of nigerythrin Phyre2 PDB 3zyq chain A Region: 6 - 58 Aligned: 46 Modelled: 46 Confidence: 65.6% Identity: 22% PDB header:signaling Chain: A: PDB Molecule:hepatocyte growth factor-regulated tyrosine kinase PDBTitle: crystal structure of the tandem vhs and fyve domains of hepatocyte2 growth factor-regulated tyrosine kinase substrate (hgs-hrs) at 1.483 a resolution Phyre2 PDB 1ryq chain A Region: 226 - 253 Aligned: 25 Modelled: 25 Confidence: 64.6% Identity: 36% Fold: Rubredoxin-like Superfamily: RNA polymerase subunits Family: RpoE2-like Phyre2 PDB 3ky9 chain B Region: 232 - 252 Aligned: 21 Modelled: 21 Confidence: 63.8% Identity: 29% PDB header:apoptosis Chain: B: PDB Molecule:proto-oncogene vav; PDBTitle: autoinhibited vav1 Phyre2 1 c2pptA_ 2 c2lcqA_ 3 c2hr5B_ 4 d1dl6a_ 5 c2f9iD_ 6 d1akya2 7 d2ak3a2 8 d1p3ja2 9 d2f9yb1 10 c2f9yB_ 11 d1zina2 12 d1s3ga2 13 c1dvbA_ 14 d1k3xa3 15 d1yc5a1 16 d1e4va2 17 c1hk8A_ 18 d1hk8a_ 19 c2gb5B_ 20 d2gnra1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 d2cona1 64 65 66 67 c2odxA_ 68 69 70 71 c1yuzB_ 72 73 74 75 76 77 c3zyqA_ 78 79 80 d1ryqa_ 81 82 83 c3ky9B_ 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2pptA_ 94.6 17 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin-2; PDBTitle: crystal structure of thioredoxin-2 2 c2lcqA_ 92.8 25 PDB header:metal binding protein Chain: A: PDB Molecule:putative toxin vapc6; PDBTitle: solution structure of the endonuclease nob1 from p.horikoshii 3 c2hr5B_ 92.0 30 PDB header:metal binding protein Chain: B: PDB Molecule:rubrerythrin; PDBTitle: pf1283- rubrerythrin from pyrococcus furiosus iron bound form 4 d1dl6a_ 91.1 18 Fold:Rubredoxin-like Superfamily:Zinc beta-ribbon Family:Transcriptional factor domain 5 c2f9iD_ 90.8 17 PDB header:transferase Chain: D: PDB Molecule:acetyl-coenzyme a carboxylase carboxyl PDBTitle: crystal structure of the carboxyltransferase subunit of acc2 from staphylococcus aureus 6 d1akya2 90.5 5 Fold:Rubredoxin-like Superfamily:Microbial and mitochondrial ADK, insert "zinc finger" domain Family:Microbial and mitochondrial ADK, insert "zinc finger" domain 7 d2ak3a2 89.8 6 Fold:Rubredoxin-like Superfamily:Microbial and mitochondrial ADK, insert "zinc finger" domain Family:Microbial and mitochondrial ADK, insert "zinc finger" domain 8 d1p3ja2 89.4 12 Fold:Rubredoxin-like Superfamily:Microbial and mitochondrial ADK, insert "zinc finger" domain Family:Microbial and mitochondrial ADK, insert "zinc finger" domain 9 d2f9yb1 89.1 22 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Biotin dependent carboxylase carboxyltransferase domain 10 c2f9yB_ 89.1 22 PDB header:ligase Chain: B: PDB Molecule:acetyl-coenzyme a carboxylase carboxyl transferase subunit PDBTitle: the crystal structure of the carboxyltransferase subunit of acc from2 escherichia coli 11 d1zina2 88.9 15 Fold:Rubredoxin-like Superfamily:Microbial and mitochondrial ADK, insert "zinc finger" domain Family:Microbial and mitochondrial ADK, insert "zinc finger" domain 12 d1s3ga2 88.8 12 Fold:Rubredoxin-like Superfamily:Microbial and mitochondrial ADK, insert "zinc finger" domain Family:Microbial and mitochondrial ADK, insert "zinc finger" domain 13 c1dvbA_ 87.6 22 PDB header:electron transport Chain: A: PDB Molecule:rubrerythrin; PDBTitle: rubrerythrin 14 d1k3xa3 87.4 27 Fold:Glucocorticoid receptor-like (DNA-binding domain) Superfamily:Glucocorticoid receptor-like (DNA-binding domain) Family:C-terminal, Zn-finger domain of MutM-like DNA repair proteins 15 d1yc5a1 87.3 24 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 16 d1e4va2 86.7 0 Fold:Rubredoxin-like Superfamily:Microbial and mitochondrial ADK, insert "zinc finger" domain Family:Microbial and mitochondrial ADK, insert "zinc finger" domain 17 c1hk8A_ 86.4 14 PDB header:oxidoreductase Chain: A: PDB Molecule:anaerobic ribonucleotide-triphosphate reductase; PDBTitle: structural basis for allosteric substrate specificity2 regulation in class iii ribonucleotide reductases:3 nrdd in complex with dgtp 18 d1hk8a_ 86.4 14 Fold:PFL-like glycyl radical enzymes Superfamily:PFL-like glycyl radical enzymes Family:Class III anaerobic ribonucleotide reductase NRDD subunit 19 c2gb5B_ 86.0 14 PDB header:hydrolase Chain: B: PDB Molecule:nadh pyrophosphatase; PDBTitle: crystal structure of nadh pyrophosphatase (ec 3.6.1.22) (1790429) from2 escherichia coli k12 at 2.30 a resolution 20 d2gnra1 86.0 29 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:SSO2064-like 21 d1ee8a3 not modelled 85.5 26 Fold:Glucocorticoid receptor-like (DNA-binding domain) Superfamily:Glucocorticoid receptor-like (DNA-binding domain) Family:C-terminal, Zn-finger domain of MutM-like DNA repair proteins 22 c3na7A_ not modelled 85.4 18 PDB header:gene regulation, chaperone Chain: A: PDB Molecule:hp0958; PDBTitle: 2.2 angstrom structure of the hp0958 protein from helicobacter pylori2 ccug 17874 23 d1pfta_ not modelled 84.9 17 Fold:Rubredoxin-like Superfamily:Zinc beta-ribbon Family:Transcriptional factor domain 24 d1m2ka_ not modelled 84.4 21 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 25 d2gmga1 not modelled 84.0 24 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:PF0610-like 26 c3glsC_ not modelled 83.7 21 PDB header:hydrolase Chain: C: PDB Molecule:nad-dependent deacetylase sirtuin-3, PDBTitle: crystal structure of human sirt3 27 c2kdxA_ not modelled 83.5 29 PDB header:metal-binding protein Chain: A: PDB Molecule:hydrogenase/urease nickel incorporation protein PDBTitle: solution structure of hypa protein 28 c3a44D_ not modelled 83.4 30 PDB header:metal binding protein Chain: D: PDB Molecule:hydrogenase nickel incorporation protein hypa; PDBTitle: crystal structure of hypa in the dimeric form 29 d1tdza3 not modelled 83.2 26 Fold:Glucocorticoid receptor-like (DNA-binding domain) Superfamily:Glucocorticoid receptor-like (DNA-binding domain) Family:C-terminal, Zn-finger domain of MutM-like DNA repair proteins 30 c3lpeF_ not modelled 82.1 24 PDB header:transferase Chain: F: PDB Molecule:dna-directed rna polymerase subunit e''; PDBTitle: crystal structure of spt4/5ngn heterodimer complex from methanococcus2 jannaschii 31 c3k7aM_ not modelled 81.9 24 PDB header:transcription Chain: M: PDB Molecule:transcription initiation factor iib; PDBTitle: crystal structure of an rna polymerase ii-tfiib complex 32 d1lkoa2 not modelled 81.5 25 Fold:Rubredoxin-like Superfamily:Rubredoxin-like Family:Rubredoxin 33 c3k35D_ not modelled 81.4 19 PDB header:hydrolase Chain: D: PDB Molecule:nad-dependent deacetylase sirtuin-6; PDBTitle: crystal structure of human sirt6 34 c3p2aB_ not modelled 81.3 32 PDB header:oxidoreductase Chain: B: PDB Molecule:putative thioredoxin-like protein; PDBTitle: crystal structure of thioredoxin 2 from yersinia pestis 35 d2ct7a1 not modelled 80.6 28 Fold:RING/U-box Superfamily:RING/U-box Family:IBR domain 36 d1k82a3 not modelled 80.5 24 Fold:Glucocorticoid receptor-like (DNA-binding domain) Superfamily:Glucocorticoid receptor-like (DNA-binding domain) Family:C-terminal, Zn-finger domain of MutM-like DNA repair proteins 37 d1l1ta3 not modelled 80.5 32 Fold:Glucocorticoid receptor-like (DNA-binding domain) Superfamily:Glucocorticoid receptor-like (DNA-binding domain) Family:C-terminal, Zn-finger domain of MutM-like DNA repair proteins 38 d1q1aa_ not modelled 80.4 21 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 39 d1r2za3 not modelled 79.2 32 Fold:Glucocorticoid receptor-like (DNA-binding domain) Superfamily:Glucocorticoid receptor-like (DNA-binding domain) Family:C-terminal, Zn-finger domain of MutM-like DNA repair proteins 40 d1weoa_ not modelled 78.7 22 Fold:RING/U-box Superfamily:RING/U-box Family:RING finger domain, C3HC4 41 c2ja6L_ not modelled 77.6 26 PDB header:transferase Chain: L: PDB Molecule:dna-directed rna polymerases i, ii, and iii 7.7 PDBTitle: cpd lesion containing rna polymerase ii elongation complex2 b 42 c3h0gL_ not modelled 77.5 19 PDB header:transcription Chain: L: PDB Molecule:dna-directed rna polymerases i, ii, and iii PDBTitle: rna polymerase ii from schizosaccharomyces pombe 43 d2akla2 not modelled 76.3 28 Fold:Rubredoxin-like Superfamily:Zinc beta-ribbon Family:PhnA zinc-binding domain 44 c2aklA_ not modelled 76.0 28 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:phna-like protein pa0128; PDBTitle: solution structure for phn-a like protein pa0128 from2 pseudomonas aeruginosa 45 c3pkiF_ not modelled 75.9 16 PDB header:hydrolase Chain: F: PDB Molecule:nad-dependent deacetylase sirtuin-6; PDBTitle: human sirt6 crystal structure in complex with adp ribose 46 c1i3qI_ not modelled 75.2 19 PDB header:transcription Chain: I: PDB Molecule:dna-directed rna polymerase ii 14.2kd PDBTitle: rna polymerase ii crystal form i at 3.1 a resolution 47 c3axtA_ not modelled 75.1 22 PDB header:transferase Chain: A: PDB Molecule:probable n(2),n(2)-dimethylguanosine trna methyltransferase PDBTitle: complex structure of trna methyltransferase trm1 from aquifex aeolicus2 with s-adenosyl-l-methionine 48 d1yuza2 not modelled 74.5 22 Fold:Rubredoxin-like Superfamily:Rubredoxin-like Family:Rubredoxin 49 c3p2aA_ not modelled 73.1 31 PDB header:oxidoreductase Chain: A: PDB Molecule:putative thioredoxin-like protein; PDBTitle: crystal structure of thioredoxin 2 from yersinia pestis 50 d6rxna_ not modelled 72.9 23 Fold:Rubredoxin-like Superfamily:Rubredoxin-like Family:Rubredoxin 51 c2jrpA_ not modelled 72.2 37 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative cytoplasmic protein; PDBTitle: solution nmr structure of yfgj from salmonella typhimurium2 modeled with two zn+2 bound, northeast structural genomics3 consortium target str86 52 d2dsxa1 not modelled 72.2 26 Fold:Rubredoxin-like Superfamily:Rubredoxin-like Family:Rubredoxin 53 c3cngC_ not modelled 72.0 25 PDB header:hydrolase Chain: C: PDB Molecule:nudix hydrolase; PDBTitle: crystal structure of nudix hydrolase from nitrosomonas europaea 54 d1qcva_ not modelled 71.7 11 Fold:Rubredoxin-like Superfamily:Rubredoxin-like Family:Rubredoxin 55 c1q14A_ not modelled 71.7 16 PDB header:hydrolase Chain: A: PDB Molecule:hst2 protein; PDBTitle: structure and autoregulation of the yeast hst2 homolog of sir2 56 d2dkta1 not modelled 71.2 24 Fold:CHY zinc finger-like Superfamily:CHY zinc finger-like Family:CHY zinc finger 57 d4rxna_ not modelled 70.9 22 Fold:Rubredoxin-like Superfamily:Rubredoxin-like Family:Rubredoxin 58 c2x5cB_ not modelled 70.5 60 PDB header:viral protein Chain: B: PDB Molecule:hypothetical protein orf131; PDBTitle: crystal structure of hypothetical protein orf131 from2 pyrobaculum spherical virus 59 d1iroa_ not modelled 70.0 22 Fold:Rubredoxin-like Superfamily:Rubredoxin-like Family:Rubredoxin 60 c3jwpA_ not modelled 68.9 15 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulatory protein sir2 homologue; PDBTitle: crystal structure of plasmodium falciparum sir2a (pf13_0152) in2 complex with amp 61 d2k4xa1 not modelled 68.6 25 Fold:Rubredoxin-like Superfamily:Zn-binding ribosomal proteins Family:Ribosomal protein S27a 62 c2v3bB_ not modelled 68.3 22 PDB header:oxidoreductase Chain: B: PDB Molecule:rubredoxin 2; PDBTitle: crystal structure of the electron transfer complex2 rubredoxin - rubredoxin reductase from pseudomonas3 aeruginosa. 63 d2cona1 68.0 28 Fold:Rubredoxin-like Superfamily:NOB1 zinc finger-like Family:NOB1 zinc finger-like 64 c1s24A_ not modelled 68.0 30 PDB header:electron transport Chain: A: PDB Molecule:rubredoxin 2; PDBTitle: rubredoxin domain ii from pseudomonas oleovorans 65 d1s24a_ not modelled 68.0 30 Fold:Rubredoxin-like Superfamily:Rubredoxin-like Family:Rubredoxin 66 c2js4A_ not modelled 67.8 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0434 protein bb2007; PDBTitle: solution nmr structure of bordetella bronchiseptica protein2 bb2007. northeast structural genomics consortium target3 bor54 67 c2odxA_ 67.8 19 PDB header:oxidoreductase Chain: A: PDB Molecule:cytochrome c oxidase polypeptide iv; PDBTitle: solution structure of zn(ii)cox4 68 d2ey4e1 not modelled 67.1 22 Fold:Rubredoxin-like Superfamily:Nop10-like SnoRNP Family:Nucleolar RNA-binding protein Nop10-like 69 d1p91a_ not modelled 67.0 33 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:rRNA methyltransferase RlmA 70 d1nnqa2 not modelled 66.8 35 Fold:Rubredoxin-like Superfamily:Rubredoxin-like Family:Rubredoxin 71 c1yuzB_ 66.8 27 PDB header:oxidoreductase Chain: B: PDB Molecule:nigerythrin; PDBTitle: partially reduced state of nigerythrin 72 d1qxfa_ not modelled 66.3 14 Fold:Rubredoxin-like Superfamily:Zn-binding ribosomal proteins Family:Ribosomal protein S27e 73 d2apob1 not modelled 66.2 27 Fold:Rubredoxin-like Superfamily:Nop10-like SnoRNP Family:Nucleolar RNA-binding protein Nop10-like 74 d2pk7a1 not modelled 66.0 19 Fold:Trm112p-like Superfamily:Trm112p-like Family:Trm112p-like 75 c2kn9A_ not modelled 66.0 33 PDB header:electron transport Chain: A: PDB Molecule:rubredoxin; PDBTitle: solution structure of zinc-substituted rubredoxin b (rv3250c) from2 mycobacterium tuberculosis. seattle structural genomics center for3 infectious disease target mytud.01635.a 76 c2jr6A_ not modelled 65.9 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0434 protein nma0874; PDBTitle: solution structure of upf0434 protein nma0874. northeast structural2 genomics target mr32 77 c3zyqA_ 65.6 22 PDB header:signaling Chain: A: PDB Molecule:hepatocyte growth factor-regulated tyrosine kinase PDBTitle: crystal structure of the tandem vhs and fyve domains of hepatocyte2 growth factor-regulated tyrosine kinase substrate (hgs-hrs) at 1.483 a resolution 78 c2pziA_ not modelled 65.2 18 PDB header:transferase Chain: A: PDB Molecule:probable serine/threonine-protein kinase pkng; PDBTitle: crystal structure of protein kinase pkng from mycobacterium2 tuberculosis in complex with tetrahydrobenzothiophene ax20017 79 c3floD_ not modelled 64.8 29 PDB header:transferase Chain: D: PDB Molecule:dna polymerase alpha catalytic subunit a; PDBTitle: crystal structure of the carboxyl-terminal domain of yeast2 dna polymerase alpha in complex with its b subunit 80 d1ryqa_ 64.6 36 Fold:Rubredoxin-like Superfamily:RNA polymerase subunits Family:RpoE2-like 81 d2jnya1 not modelled 64.5 19 Fold:Trm112p-like Superfamily:Trm112p-like Family:Trm112p-like 82 d2fiya1 not modelled 64.3 22 Fold:FdhE-like Superfamily:FdhE-like Family:FdhE-like 83 c3ky9B_ 63.8 29 PDB header:apoptosis Chain: B: PDB Molecule:proto-oncogene vav; PDBTitle: autoinhibited vav1 84 d1dx8a_ not modelled 63.3 22 Fold:Rubredoxin-like Superfamily:Rubredoxin-like Family:Rubredoxin 85 d1h7va_ not modelled 62.0 22 Fold:Rubredoxin-like Superfamily:Rubredoxin-like Family:Rubredoxin 86 c3gn5B_ not modelled 61.3 25 PDB header:dna binding protein Chain: B: PDB Molecule:hth-type transcriptional regulator mqsa (ygit/b3021); PDBTitle: structure of the e. coli protein mqsa (ygit/b3021) 87 d1iu5a_ not modelled 61.0 26 Fold:Rubredoxin-like Superfamily:Rubredoxin-like Family:Rubredoxin 88 d2rdva_ not modelled 58.8 26 Fold:Rubredoxin-like Superfamily:Rubredoxin-like Family:Rubredoxin 89 d2j0151 not modelled 57.6 27 Fold:Rubredoxin-like Superfamily:Zn-binding ribosomal proteins Family:Ribosomal protein L32p 90 c3iz6X_ not modelled 57.3 20 PDB header:ribosome Chain: X: PDB Molecule:40s ribosomal protein s27 (s27e); PDBTitle: localization of the small subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome 91 d2hf1a1 not modelled 57.0 19 Fold:Trm112p-like Superfamily:Trm112p-like Family:Trm112p-like 92 c3f2cA_ not modelled 56.6 22 PDB header:transferase/dna Chain: A: PDB Molecule:geobacillus kaustophilus dna polc; PDBTitle: dna polymerase polc from geobacillus kaustophilus complex with dna,2 dgtp and mn 93 d1rb9a_ not modelled 56.3 30 Fold:Rubredoxin-like Superfamily:Rubredoxin-like Family:Rubredoxin 94 c3h0gI_ not modelled 55.0 15 PDB header:transcription Chain: I: PDB Molecule:dna-directed rna polymerase ii subunit rpb9; PDBTitle: rna polymerase ii from schizosaccharomyces pombe 95 d1brfa_ not modelled 54.9 32 Fold:Rubredoxin-like Superfamily:Rubredoxin-like Family:Rubredoxin 96 d2zjrz1 not modelled 54.4 33 Fold:Rubredoxin-like Superfamily:Zn-binding ribosomal proteins Family:Ribosomal protein L32p 97 d1j8fa_ not modelled 53.8 22 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 98 c2opfA_ not modelled 53.7 27 PDB header:hydrolase/dna Chain: A: PDB Molecule:endonuclease viii; PDBTitle: crystal structure of the dna repair enzyme endonuclease-viii (nei)2 from e. coli (r252a) in complex with ap-site containing dna substrate 99 d1ibia1 not modelled 53.6 30 Fold:Glucocorticoid receptor-like (DNA-binding domain) Superfamily:Glucocorticoid receptor-like (DNA-binding domain) Family:LIM domain 100 c1k82D_ not modelled 53.4 20 PDB header:hydrolase/dna Chain: D: PDB Molecule:formamidopyrimidine-dna glycosylase; PDBTitle: crystal structure of e.coli formamidopyrimidine-dna2 glycosylase (fpg) covalently trapped with dna 101 d2ayja1 not modelled 53.3 24 Fold:Rubredoxin-like Superfamily:Zn-binding ribosomal proteins Family:Ribosomal protein L40e 102 d1l1oc_ not modelled 52.0 24 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Single strand DNA-binding domain, SSB 103 c2kpiA_ not modelled 51.6 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein sco3027; PDBTitle: solution nmr structure of streptomyces coelicolor sco30272 modeled with zn+2 bound, northeast structural genomics3 consortium target rr58 104 c1nnjA_ not modelled 51.3 33 PDB header:hydrolase Chain: A: PDB Molecule:formamidopyrimidine-dna glycosylase; PDBTitle: crystal structure complex between the lactococcus lactis fpg and an2 abasic site containing dna 105 d2jnea1 not modelled 50.7 24 Fold:Rubredoxin-like Superfamily:YfgJ-like Family:YfgJ-like 106 c2jneA_ not modelled 50.7 24 PDB header:metal binding protein Chain: A: PDB Molecule:hypothetical protein yfgj; PDBTitle: nmr structure of e.coli yfgj modelled with two zn+2 bound.2 northeast structural genomics consortium target er317. 107 d1x6ma_ not modelled 50.4 15 Fold:Mss4-like Superfamily:Mss4-like Family:Glutathione-dependent formaldehyde-activating enzyme, Gfa 108 c3ir9A_ not modelled 50.0 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:peptide chain release factor subunit 1; PDBTitle: c-terminal domain of peptide chain release factor from2 methanosarcina mazei. 109 c3nw0A_ not modelled 48.7 25 PDB header:metal binding protein Chain: A: PDB Molecule:non-structural maintenance of chromosomes element 1 PDBTitle: crystal structure of mageg1 and nse1 complex 110 d1ma3a_ not modelled 47.4 18 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 111 c3u50C_ not modelled 46.7 28 PDB header:dna binding protein Chain: C: PDB Molecule:telomerase-associated protein 82; PDBTitle: crystal structure of the tetrahymena telomerase processivity factor2 teb1 ob-c 112 d2qam01 not modelled 46.5 11 Fold:Rubredoxin-like Superfamily:Zn-binding ribosomal proteins Family:Ribosomal protein L32p 113 c3h7hA_ not modelled 46.5 25 PDB header:transcription Chain: A: PDB Molecule:transcription elongation factor spt4; PDBTitle: crystal structure of the human transcription elongation factor dsif,2 hspt4/hspt5 (176-273) 114 c2f5qA_ not modelled 46.3 27 PDB header:hydrolase/dna Chain: A: PDB Molecule:formamidopyrimidine-dna glycosidase; PDBTitle: catalytically inactive (e3q) mutm crosslinked to oxog:c2 containing dna cc2 115 d1pfva3 not modelled 45.9 29 Fold:Rubredoxin-like Superfamily:Methionyl-tRNA synthetase (MetRS), Zn-domain Family:Methionyl-tRNA synthetase (MetRS), Zn-domain 116 d1ctla1 not modelled 45.8 36 Fold:Glucocorticoid receptor-like (DNA-binding domain) Superfamily:Glucocorticoid receptor-like (DNA-binding domain) Family:LIM domain 117 c1ee8A_ not modelled 45.8 20 PDB header:dna binding protein Chain: A: PDB Molecule:mutm (fpg) protein; PDBTitle: crystal structure of mutm (fpg) protein from thermus thermophilus hb8 118 d1dgsa1 not modelled 45.4 27 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:NAD+-dependent DNA ligase, domain 3 119 c3izbX_ not modelled 45.2 14 PDB header:ribosome Chain: X: PDB Molecule:40s ribosomal protein rps27 (s27e); PDBTitle: localization of the small subunit ribosomal proteins into a 6.1 a2 cryo-em map of saccharomyces cerevisiae translating 80s ribosome 120 c1ltlE_ not modelled 43.5 14 PDB header:replication Chain: E: PDB Molecule:dna replication initiator (cdc21/cdc54); PDBTitle: the dodecamer structure of mcm from archaeal m.2 thermoautotrophicum

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0