PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2opfA_

Fold library id	PDB Header	Molecule	Title
c2opfA_	PDB header: hydrolase/dna	Chain: A: PDB Molecule: endonuclease viii;	PDBTitle: crystal structure of the dna repair enzyme endonuclease-2 viii (nei) from e. coli (r252a) in complex with ap-site3 containing dna substrate

Links to external resources
Added to library: Tue Mar 16 12:36:50 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence P E G P E I R R A A D N L E A A I K G K P L T D V W F A F P Q L K T Y Q S Q L I G Q H V T H V E T R G K A L L T H F S N D L T L Y S H N Q L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
B T
B S S G G G T T T T
B T T T T S
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence Y G V W R V V D T G E E P Q T T R V L R V K L Q T A D K T I L L Y S A S D I E M L R P E Q L T T H P F L Q R V G P D V L D P N L T P E V V K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T T
S
S S S
T
B T T
T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence E R L L S P R F R N R Q F A G L L L D Q A F L A G L G N Y L R V E I L W Q V G L T G N H K A K D L N A A Q L D A L A H A L L E I P R F S Y A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S T T T T T S B T T
T T T S B T
T T
T T
B G G G S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . .

Sequence T R G Q V D A L F R F K V F H R D G E P C E R C G S I I E K T T L S S A P F Y W C P G C Q H

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T
S S T T
T T S B
T T T
B
T T
T T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	P	E	G	P	E	I	R	R	A	A	D	N	L	E	A	A	I	K	G	K	P	L	T	D	V	W	F	A	F	P	Q	L	K	T	Y	Q	S	Q	L	I	G	Q	H	V	T	H	V	E	T	R	G	K	A	L	L	T	H	F	S	N	D	L	T	L	Y	S	H	N	Q	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																		B	T		B							S	S	G	G	G	T	T						T	T		B								T	T							T	T	S								T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	Y	G	V	W	R	V	V	D	T	G	E	E	P	Q	T	T	R	V	L	R	V	K	L	Q	T	A	D	K	T	I	L	L	Y	S	A	S	D	I	E	M	L	R	P	E	Q	L	T	T	H	P	F	L	Q	R	V	G	P	D	V	L	D	P	N	L	T	P	E	V	V	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T								T	T							S									S	S							S														T										B	T	T		T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	E	R	L	L	S	P	R	F	R	N	R	Q	F	A	G	L	L	L	D	Q	A	F	L	A	G	L	G	N	Y	L	R	V	E	I	L	W	Q	V	G	L	T	G	N	H	K	A	K	D	L	N	A	A	Q	L	D	A	L	A	H	A	L	L	E	I	P	R	F	S	Y	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					S	T	T	T	T	T	S	B					T	T		T	T	T	S	B	T													T	T			T	T		B	G	G	G	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.
Sequence	T	R	G	Q	V	D	A	L	F	R	F	K	V	F	H	R	D	G	E	P	C	E	R	C	G	S	I	I	E	K	T	T	L	S	S	A	P	F	Y	W	C	P	G	C	Q	H
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T	T								S	S	T	T		T	T	S	B		T	T	T			B							T	T							T	T	T