Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	Q	G	T	K	I	R	L	L	A	G	G	L	L	M	M	A	T	A	G	Y	V	Q	A	D	A	L	Q	P	D	P	A	W	Q	Q	G	T	L	S	N	G	L	Q	W	Q	V	L	T	T	P	Q	R	P	S	D	R	V	E	I	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?													?	?	?	?	?	?	?	?	?	?	?	?	?																					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	L	V	N	T	G	S	L	A	E	S	T	Q	Q	S	G	Y	S	H	A	I	P	R	I	A	L	T	Q	S	G	G	L	D	A	A	Q	A	R	S	L	W	Q	Q	G	I	D	P	K	R	P	M	P	P	V	I	V	S	Y	D	T
Secondary structure
SS confidence
Disorder													?																				?	?														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		T	L	F	N	L	S	L	P	N	N	R	N	D	L	L	K	E	A	L	S	Y	L	A	N	A	T	G	K	L	T	I	T	P	E	T	I	N	H	A	L	Q	S	Q	D	M	V	A	T	W	P	A	D	T	K	E	G	W	W	R	Y
Secondary structure
SS confidence
Disorder																														?																			?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		R	L	K	G	S	T	L	L	G	H	D	P	A	D	P	L	K	Q	P	V	E	A	E	K	I	K	D	F	Y	Q	K	W	Y	T	P	D	A	M	T	L	L	V	V	G	N	V	D	A	R	S	V	V	D	Q	I	N	K	T	F	G
Secondary structure
SS confidence
Disorder					?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		E	L	K	G	K	R	E	T	P	A	P	V	P	T	L	S	P	L	R	A	E	A	V	S	I	M	T	D	A	V	R	Q	D	R	L	S	I	M	W	D	T	P	W	Q	P	I	R	E	S	A	A	L	L	R	Y	W	R	A	D	L
Secondary structure
SS confidence
Disorder				?	?	?	?	?	?	?	?	?	?		?	?	?	?	?																										?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		A	R	E	A	L	F	W	H	V	Q	Q	A	L	S	A	S	N	S	K	D	I	G	L	G	F	D	C	R	V	L	Y	L	R	A	Q	C	A	I	N	I	E	S	P	N	D	K	L	N	S	N	L	N	L	V	A	R	E	L	A	K
Secondary structure
SS confidence
Disorder																?	?	?	?									?	?		?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		V	R	D	K	G	L	P	E	E	E	F	N	A	L	V	A	Q	K	K	L	E	L	Q	K	L	F	A	A	Y	A	R	A	D	T	D	I	L	M	G	Q	R	M	R	S	L	Q	N	Q	V	V	D	I	A	P	E	Q	Y	Q	K	L
Secondary structure
SS confidence
Disorder																														?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		R	Q	D	F	L	N	S	L	T	V	E	M	L	N	Q	D	L	R	Q	Q	L	S	N	D	M	A	L	I	L	L	Q	P	K	G	E	P	E	F	N	M	K	A	L	Q	A	V	W	D	Q	I	M	A	P	S	T	A	A	A	T	T
Secondary structure
SS confidence
Disorder																																		?	?	?	?	?	?	?												?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.
Sequence		S	V	A	T	D	D	V	H	P	E	V	T	D	I	P	P	A	Q
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3go9 chain A Region: 18 - 472 Aligned: 455 Modelled: 455 Confidence: 100.0% Identity: 60% PDB header:hydrolase Chain: A: PDB Molecule:insulinase family protease; PDBTitle: predicted insulinase family protease from yersinia pestis Phyre2 PDB 1sqp chain A Region: 20 - 465 Aligned: 424 Modelled: 440 Confidence: 100.0% Identity: 13% PDB header:oxidoreductase Chain: A: PDB Molecule:ubiquinol-cytochrome-c reductase complex core protein i, PDBTitle: crystal structure analysis of bovine bc1 with myxothiazol Phyre2 PDB 1hr9 chain D Region: 31 - 469 Aligned: 419 Modelled: 432 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: D: PDB Molecule:mitochondrial processing peptidase beta subunit; PDBTitle: yeast mitochondrial processing peptidase beta-e73q mutant2 complexed with malate dehydrogenase signal peptide Phyre2 PDB 1nu1 chain A Region: 20 - 465 Aligned: 424 Modelled: 442 Confidence: 100.0% Identity: 13% PDB header:oxidoreductase Chain: A: PDB Molecule:ubiquinol-cytochrome c reductase complex core protein i, PDBTitle: crystal structure of mitochondrial cytochrome bc1 complexed with 2-2 nonyl-4-hydroxyquinoline n-oxide (nqno) Phyre2 PDB 1q2l chain A Region: 26 - 455 Aligned: 412 Modelled: 418 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:protease iii; PDBTitle: crystal structure of pitrilysin Phyre2 PDB 2wk3 chain A Region: 26 - 459 Aligned: 415 Modelled: 427 Confidence: 100.0% Identity: 12% PDB header:hydrolase Chain: A: PDB Molecule:insulin degrading enzyme; PDBTitle: crystal structure of human insulin-degrading enzyme in2 complex with amyloid-beta (1-42) Phyre2 PDB 2jbu chain B Region: 26 - 459 Aligned: 415 Modelled: 430 Confidence: 100.0% Identity: 12% PDB header:hydrolase Chain: B: PDB Molecule:insulin-degrading enzyme; PDBTitle: crystal structure of human insulin degrading enzyme2 complexed with co-purified peptides. Phyre2 PDB 1hr6 chain C Region: 32 - 467 Aligned: 416 Modelled: 431 Confidence: 100.0% Identity: 13% PDB header:hydrolase Chain: C: PDB Molecule:mitochondrial processing peptidase alpha subunit; PDBTitle: yeast mitochondrial processing peptidase Phyre2 PDB 3hdi chain A Region: 33 - 458 Aligned: 402 Modelled: 416 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:processing protease; PDBTitle: crystal structure of bacillus halodurans metallo peptidase Phyre2 PDB 3ami chain B Region: 29 - 453 Aligned: 407 Modelled: 421 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: B: PDB Molecule:zinc peptidase; PDBTitle: the crystal structure of the m16b metallopeptidase subunit from2 sphingomonas sp. a1 Phyre2 PDB 3eoq chain B Region: 33 - 454 Aligned: 398 Modelled: 419 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: B: PDB Molecule:putative zinc protease; PDBTitle: the crystal structure of putative zinc protease beta-2 subunit from thermus thermophilus hb8 Phyre2 PDB 3gwb chain A Region: 32 - 459 Aligned: 405 Modelled: 423 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:peptidase m16 inactive domain family protein; PDBTitle: crystal structure of peptidase m16 inactive domain from pseudomonas2 fluorescens. northeast structural genomics target plr293l Phyre2 PDB 2fge chain A Region: 33 - 472 Aligned: 428 Modelled: 432 Confidence: 100.0% Identity: 11% PDB header:hydrolase, plant protein Chain: A: PDB Molecule:zinc metalloprotease (insulinase family); PDBTitle: crystal structure of presequence protease prep from2 arabidopsis thaliana Phyre2 PDB 3amj chain B Region: 32 - 454 Aligned: 408 Modelled: 423 Confidence: 100.0% Identity: 12% PDB header:hydrolase Chain: B: PDB Molecule:zinc peptidase inactive subunit; PDBTitle: the crystal structure of the heterodimer of m16b peptidase from2 sphingomonas sp. a1 Phyre2 PDB 1l0l chain B Region: 28 - 452 Aligned: 397 Modelled: 422 Confidence: 100.0% Identity: 11% PDB header:oxidoreductase Chain: B: PDB Molecule:ubiquinol-cytochrome c reductase complex core protein 2; PDBTitle: structure of bovine mitochondrial cytochrome bc1 complex with a bound2 fungicide famoxadone Phyre2 PDB 3cx5 chain L Region: 36 - 465 Aligned: 402 Modelled: 408 Confidence: 100.0% Identity: 12% PDB header:oxidoreductase Chain: L: PDB Molecule:cytochrome b-c1 complex subunit 1, mitochondrial; PDBTitle: structure of complex iii with bound cytochrome c in reduced2 state and definition of a minimal core interface for3 electron transfer. Phyre2 PDB 3d3y chain A Region: 32 - 455 Aligned: 404 Modelled: 418 Confidence: 100.0% Identity: 13% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a conserved protein from enterococcus faecalis2 v583 Phyre2 PDB 3cxh chain M Region: 42 - 382 Aligned: 304 Modelled: 341 Confidence: 100.0% Identity: 13% PDB header:oxidoreductase Chain: M: PDB Molecule:cytochrome b-c1 complex subunit 2, mitochondrial; PDBTitle: structure of yeast complex iii with isoform-2 cytochrome c2 bound and definition of a minimal core interface for3 electron transfer. Phyre2 PDB 1ppj chain A domain 1 Region: 21 - 257 Aligned: 226 Modelled: 233 Confidence: 100.0% Identity: 19% Fold: LuxS/MPP-like metallohydrolase Superfamily: LuxS/MPP-like metallohydrolase Family: MPP-like Phyre2 PDB 1hr6 chain B domain 1 Region: 31 - 254 Aligned: 215 Modelled: 221 Confidence: 100.0% Identity: 19% Fold: LuxS/MPP-like metallohydrolase Superfamily: LuxS/MPP-like metallohydrolase Family: MPP-like Phyre2 1 c3go9A_ 2 c1sqpA_ 3 c1hr9D_ 4 c1nu1A_ 5 c1q2lA_ 6 c2wk3A_ 7 c2jbuB_ 8 c1hr6C_ 9 c3hdiA_ 10 c3amiB_ 11 c3eoqB_ 12 c3gwbA_ 13 c2fgeA_ 14 c3amjB_ 15 c1l0lB_ 16 c3cx5L_ 17 c3d3yA_ 18 c3cxhM_ 19 d1ppja1 20 d1hr6b1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3go9A_ 100.0 60 PDB header:hydrolase Chain: A: PDB Molecule:insulinase family protease; PDBTitle: predicted insulinase family protease from yersinia pestis 2 c1sqpA_ 100.0 13 PDB header:oxidoreductase Chain: A: PDB Molecule:ubiquinol-cytochrome-c reductase complex core protein i, PDBTitle: crystal structure analysis of bovine bc1 with myxothiazol 3 c1hr9D_ 100.0 16 PDB header:hydrolase Chain: D: PDB Molecule:mitochondrial processing peptidase beta subunit; PDBTitle: yeast mitochondrial processing peptidase beta-e73q mutant2 complexed with malate dehydrogenase signal peptide 4 c1nu1A_ 100.0 13 PDB header:oxidoreductase Chain: A: PDB Molecule:ubiquinol-cytochrome c reductase complex core protein i, PDBTitle: crystal structure of mitochondrial cytochrome bc1 complexed with 2-2 nonyl-4-hydroxyquinoline n-oxide (nqno) 5 c1q2lA_ 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:protease iii; PDBTitle: crystal structure of pitrilysin 6 c2wk3A_ 100.0 12 PDB header:hydrolase Chain: A: PDB Molecule:insulin degrading enzyme; PDBTitle: crystal structure of human insulin-degrading enzyme in2 complex with amyloid-beta (1-42) 7 c2jbuB_ 100.0 12 PDB header:hydrolase Chain: B: PDB Molecule:insulin-degrading enzyme; PDBTitle: crystal structure of human insulin degrading enzyme2 complexed with co-purified peptides. 8 c1hr6C_ 100.0 13 PDB header:hydrolase Chain: C: PDB Molecule:mitochondrial processing peptidase alpha subunit; PDBTitle: yeast mitochondrial processing peptidase 9 c3hdiA_ 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:processing protease; PDBTitle: crystal structure of bacillus halodurans metallo peptidase 10 c3amiB_ 100.0 16 PDB header:hydrolase Chain: B: PDB Molecule:zinc peptidase; PDBTitle: the crystal structure of the m16b metallopeptidase subunit from2 sphingomonas sp. a1 11 c3eoqB_ 100.0 16 PDB header:hydrolase Chain: B: PDB Molecule:putative zinc protease; PDBTitle: the crystal structure of putative zinc protease beta-2 subunit from thermus thermophilus hb8 12 c3gwbA_ 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:peptidase m16 inactive domain family protein; PDBTitle: crystal structure of peptidase m16 inactive domain from pseudomonas2 fluorescens. northeast structural genomics target plr293l 13 c2fgeA_ 100.0 11 PDB header:hydrolase, plant protein Chain: A: PDB Molecule:zinc metalloprotease (insulinase family); PDBTitle: crystal structure of presequence protease prep from2 arabidopsis thaliana 14 c3amjB_ 100.0 12 PDB header:hydrolase Chain: B: PDB Molecule:zinc peptidase inactive subunit; PDBTitle: the crystal structure of the heterodimer of m16b peptidase from2 sphingomonas sp. a1 15 c1l0lB_ 100.0 11 PDB header:oxidoreductase Chain: B: PDB Molecule:ubiquinol-cytochrome c reductase complex core protein 2; PDBTitle: structure of bovine mitochondrial cytochrome bc1 complex with a bound2 fungicide famoxadone 16 c3cx5L_ 100.0 12 PDB header:oxidoreductase Chain: L: PDB Molecule:cytochrome b-c1 complex subunit 1, mitochondrial; PDBTitle: structure of complex iii with bound cytochrome c in reduced2 state and definition of a minimal core interface for3 electron transfer. 17 c3d3yA_ 100.0 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a conserved protein from enterococcus faecalis2 v583 18 c3cxhM_ 100.0 13 PDB header:oxidoreductase Chain: M: PDB Molecule:cytochrome b-c1 complex subunit 2, mitochondrial; PDBTitle: structure of yeast complex iii with isoform-2 cytochrome c2 bound and definition of a minimal core interface for3 electron transfer. 19 d1ppja1 100.0 19 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:MPP-like 20 d1hr6b1 100.0 19 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:MPP-like 21 d1bcca1 not modelled 100.0 18 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:MPP-like 22 d2fgea4 not modelled 100.0 9 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:MPP-like 23 d1hr6a1 not modelled 100.0 17 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:MPP-like 24 d1q2la4 not modelled 100.0 19 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:MPP-like 25 d1ppjb1 not modelled 100.0 15 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:MPP-like 26 d1bccb1 not modelled 100.0 15 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:MPP-like 27 d3cx5b1 not modelled 100.0 15 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:MPP-like 28 d3cx5a1 not modelled 100.0 14 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:MPP-like 29 d1hr6b2 not modelled 99.9 12 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:MPP-like 30 c3ivlA_ not modelled 99.9 10 PDB header:hydrolase Chain: A: PDB Molecule:putative zinc protease; PDBTitle: the crystal structure of the inactive peptidase domain of a putative2 zinc protease from bordetella parapertussis to 2.2a 31 d1bcca2 not modelled 99.8 8 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:MPP-like 32 d1ppjb2 not modelled 99.8 6 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:MPP-like 33 d1q2la1 not modelled 99.8 9 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:MPP-like 34 d1ppja2 not modelled 99.8 8 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:MPP-like 35 d1hr6a2 not modelled 99.8 9 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:MPP-like 36 d3cx5a2 not modelled 99.8 9 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:MPP-like 37 d1bccb2 not modelled 99.8 6 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:MPP-like 38 d2fgea3 not modelled 99.7 11 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:MPP-like 39 d2fgea2 not modelled 99.6 6 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:MPP-like 40 d1q2la2 not modelled 98.8 7 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:MPP-like 41 d2fgea1 not modelled 98.5 10 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:MPP-like 42 d1q2la3 not modelled 98.4 11 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:MPP-like 43 c1g6uB_ not modelled 60.1 28 PDB header:de novo protein Chain: B: PDB Molecule:domain swapped dimer; PDBTitle: crystal structure of a domain swapped dimer 44 c3fhkF_ not modelled 56.1 18 PDB header:structural genomics, unknown function Chain: F: PDB Molecule:upf0403 protein yphp; PDBTitle: crystal structure of apc1446, b.subtilis yphp disulfide2 isomerase 45 d1g5ta_ not modelled 21.7 17 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RecA protein-like (ATPase-domain) 46 c3l7vA_ not modelled 20.1 10 PDB header:transcription Chain: A: PDB Molecule:putative uncharacterized protein smu.1377c; PDBTitle: crystal structure of a hypothetical protein smu.1377c from2 streptococcus mutans ua159 47 d2rdea1 not modelled 16.0 4 Fold:Split barrel-like Superfamily:PilZ domain-like Family:PilZ domain 48 d1q5ma_ not modelled 15.5 40 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 49 c2qruA_ not modelled 13.9 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an alpha/beta hydrolase superfamily protein from2 enterococcus faecalis 50 d1tuza_ not modelled 13.9 5 Fold:EF Hand-like Superfamily:EF-hand Family:EF-hand modules in multidomain proteins 51 d1g64b_ not modelled 13.8 17 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RecA protein-like (ATPase-domain) 52 c2bh7A_ not modelled 13.5 14 PDB header:hydrolase Chain: A: PDB Molecule:n-acetylmuramoyl-l-alanine amidase; PDBTitle: crystal structure of a semet derivative of amid at 2.22 angstroms 53 d1fe0a_ not modelled 13.1 4 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 54 c3gnnA_ not modelled 12.0 21 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of nicotinate-nucleotide2 pyrophosphorylase from burkholderi pseudomallei 55 c2yw3E_ not modelled 11.9 15 PDB header:lyase Chain: E: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase/2-deydro-3- PDBTitle: crystal structure analysis of the 4-hydroxy-2-oxoglutarate aldolase/2-2 deydro-3-deoxyphosphogluconate aldolase from tthb1 56 d1yira1 not modelled 11.9 24 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:Monomeric nicotinate phosphoribosyltransferase C-terminal domain 57 c2x3dC_ not modelled 11.4 5 PDB header:unknown function Chain: C: PDB Molecule:sso6206; PDBTitle: crystal structure of sso6206 from sulfolobus solfataricus p2 58 c1d2fB_ not modelled 11.4 21 PDB header:transferase Chain: B: PDB Molecule:maly protein; PDBTitle: x-ray structure of maly from escherichia coli: a pyridoxal-5'-2 phosphate-dependent enzyme acting as a modulator in mal gene3 expression 59 d1d2fa_ not modelled 11.3 21 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:Cystathionine synthase-like 60 c2pbrB_ not modelled 11.1 10 PDB header:transferase Chain: B: PDB Molecule:thymidylate kinase; PDBTitle: crystal structure of thymidylate kinase (aq_969) from aquifex aeolicus2 vf5 61 c3lv8A_ not modelled 10.7 12 PDB header:transferase Chain: A: PDB Molecule:thymidylate kinase; PDBTitle: 1.8 angstrom resolution crystal structure of a thymidylate kinase2 (tmk) from vibrio cholerae o1 biovar eltor str. n16961 in complex3 with tmp, thymidine-5'-diphosphate and adp 62 c3pajA_ not modelled 10.1 11 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase, carboxylating; PDBTitle: 2.00 angstrom resolution crystal structure of a quinolinate2 phosphoribosyltransferase from vibrio cholerae o1 biovar eltor str.3 n16961 63 c1x1oC_ not modelled 9.8 11 PDB header:transferase Chain: C: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of project id tt0268 from thermus thermophilus hb8 64 c1qapA_ not modelled 9.7 16 PDB header:glycosyltransferase Chain: A: PDB Molecule:quinolinic acid phosphoribosyltransferase; PDBTitle: quinolinic acid phosphoribosyltransferase with bound2 quinolinic acid 65 d1pn0a3 not modelled 9.7 11 Fold:FAD-linked reductases, C-terminal domain Superfamily:FAD-linked reductases, C-terminal domain Family:PHBH-like 66 c1i5kD_ not modelled 9.5 23 PDB header:blood clotting Chain: D: PDB Molecule:m protein; PDBTitle: structure and binding determinants of the recombinant kringle-2 domain2 of human plasminogen to an internal peptide from a group a3 streptococcal surface protein 67 c1i5kC_ not modelled 9.5 23 PDB header:blood clotting Chain: C: PDB Molecule:m protein; PDBTitle: structure and binding determinants of the recombinant kringle-2 domain2 of human plasminogen to an internal peptide from a group a3 streptococcal surface protein 68 c3ostA_ not modelled 8.5 10 PDB header:lipid binding protein Chain: A: PDB Molecule:serine/threonine-protein kinase kcc4; PDBTitle: structure of the kinase associated-1 (ka1) from kcc4p 69 c2kj4B_ not modelled 8.4 23 PDB header:blood clotting Chain: B: PDB Molecule:vek-30; PDBTitle: solution structure of the complex of vek-30 and plasminogen2 kringle 2 70 d2raqa1 not modelled 8.3 18 Fold:Ferredoxin-like Superfamily:MTH889-like Family:MTH889-like 71 c3qspB_ not modelled 8.1 19 PDB header:hydrolase Chain: B: PDB Molecule:putative uncharacterized protein; PDBTitle: analysis of a new family of widely distributed metal-independent alpha2 mannosidases provides unique insight into the processing of n-linked3 glycans, streptococcus pneumoniae sp_2144 non-productive substrate4 complex with alpha-1,6-mannobiose 72 c2h18A_ not modelled 8.1 23 PDB header:transport protein Chain: A: PDB Molecule:adp-ribosylation factor-like protein 8a; PDBTitle: structure of human adp-ribosylation factor-like 10b (arl10b) 73 d1geha2 not modelled 8.1 13 Fold:Ferredoxin-like Superfamily:RuBisCO, large subunit, small (N-terminal) domain Family:Ribulose 1,5-bisphosphate carboxylase-oxygenase 74 c2doiB_ not modelled 8.0 23 PDB header:hydrolase Chain: B: PDB Molecule:plasminogen-binding group a streptococcal m-like protein PDBTitle: the x-ray crystallographic structure of the angiogenesis inhibitor,2 angiostatin, bound to a peptide from the group a streptococcus3 protein pam 75 c2do6A_ not modelled 7.9 19 PDB header:ligase Chain: A: PDB Molecule:e3 ubiquitin-protein ligase cbl-b; PDBTitle: solution structure of rsgi ruh-065, a uba domain from human2 cdna 76 c3iwdC_ not modelled 7.7 23 PDB header:lyase Chain: C: PDB Molecule:s-adenosylmethionine decarboxylase; PDBTitle: t. maritima adometdc complex with 5'-deoxy-5'-dimethyl2 thioadenosine 77 c2adbA_ not modelled 7.7 14 PDB header:rna binding protein/rna Chain: A: PDB Molecule:polypyrimidine tract-binding protein 1; PDBTitle: solution structure of polypyrimidine tract binding protein2 rbd2 complexed with cucucu rna 78 c3ihjA_ not modelled 7.7 15 PDB header:transferase Chain: A: PDB Molecule:alanine aminotransferase 2; PDBTitle: human alanine aminotransferase 2 in complex with plp 79 d1wxia1 not modelled 7.6 15 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 80 c3tl4X_ not modelled 7.6 12 PDB header:ligase Chain: X: PDB Molecule:glutaminyl-trna synthetase; PDBTitle: crystal structure of the trna binding domain of glutaminyl-trna2 synthetase from saccharomyces cerevisiae 81 c2d9sA_ not modelled 7.5 6 PDB header:ligase Chain: A: PDB Molecule:cbl e3 ubiquitin protein ligase; PDBTitle: solution structure of rsgi ruh-049, a uba domain from mouse2 cdna 82 c1z65A_ not modelled 7.5 16 PDB header:unknown function Chain: A: PDB Molecule:prion-like protein doppel; PDBTitle: mouse doppel 1-30 peptide 83 d1k8kd1 not modelled 7.5 24 Fold:Secretion chaperone-like Superfamily:Arp2/3 complex subunits Family:Arp2/3 complex subunits 84 c1yueA_ not modelled 7.4 33 PDB header:viral protein Chain: A: PDB Molecule:head vertex protein gp24; PDBTitle: bacteriophage t4 capsid vertex protein gp24 85 d1bxna2 not modelled 7.4 10 Fold:Ferredoxin-like Superfamily:RuBisCO, large subunit, small (N-terminal) domain Family:Ribulose 1,5-bisphosphate carboxylase-oxygenase 86 c2i38A_ not modelled 7.4 22 PDB header:rna binding protein/chimera Chain: A: PDB Molecule:fusion protein consists of immunoglobin g- PDBTitle: solution structure of the rrm of srp20 87 c2hvzA_ not modelled 7.3 18 PDB header:rna binding protein Chain: A: PDB Molecule:splicing factor, arginine/serine-rich 7; PDBTitle: solution structure of the rrm domain of sr rich factor 9g8 88 d1c7na_ not modelled 7.3 11 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:Cystathionine synthase-like 89 d2cq2a1 not modelled 7.2 7 Fold:Ferredoxin-like Superfamily:RNA-binding domain, RBD Family:Canonical RBD 90 c3l0gD_ not modelled 7.1 22 PDB header:transferase Chain: D: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of nicotinate-nucleotide pyrophosphorylase from2 ehrlichia chaffeensis at 2.05a resolution 91 c2r47C_ not modelled 7.1 17 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:uncharacterized protein mth_862; PDBTitle: crystal structure of mth_862 protein of unknown function from2 methanothermobacter thermautotrophicus 92 c3llkA_ not modelled 7.1 20 PDB header:oxidoreductase Chain: A: PDB Molecule:sulfhydryl oxidase 1; PDBTitle: sulfhydryl oxidase fragment of human qsox1 93 c2e5iA_ not modelled 6.9 17 PDB header:gene regulation Chain: A: PDB Molecule:heterogeneous nuclear ribonucleoprotein l-like; PDBTitle: solution structure of rna binding domain 2 in heterogeneous2 nuclear ribonucleoprotein l-like 94 d1h0ca_ not modelled 6.6 7 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:Cystathionine synthase-like 95 d1t3ta3 not modelled 6.6 14 Fold:PurS-like Superfamily:PurS-like Family:FGAM synthase PurL, PurS-like domain 96 c1w89E_ not modelled 6.5 17 PDB header:electron transport Chain: E: PDB Molecule:thioredoxin; PDBTitle: structure of the reduced form of human thioredoxin 2 97 d8ruca2 not modelled 6.5 8 Fold:Ferredoxin-like Superfamily:RuBisCO, large subunit, small (N-terminal) domain Family:Ribulose 1,5-bisphosphate carboxylase-oxygenase 98 d1nh2b_ not modelled 6.4 15 Fold:Transcription factor IIA (TFIIA), alpha-helical domain Superfamily:Transcription factor IIA (TFIIA), alpha-helical domain Family:Transcription factor IIA (TFIIA), alpha-helical domain 99 d1nvpb_ not modelled 6.3 19 Fold:Transcription factor IIA (TFIIA), alpha-helical domain Superfamily:Transcription factor IIA (TFIIA), alpha-helical domain Family:Transcription factor IIA (TFIIA), alpha-helical domain

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0