Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	I	L	I	D	K	N	T	K	V	I	C	Q	G	F	T	G	S	Q	G	T	F	H	S	E	Q	A	I	A	Y	G	T	K	M	V	G	G	V	T	P	G	K	G	G	T	T	H	L	G	L	P	V	F	N	T	V	R	E	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	A	A	T	G	A	T	A	S	V	I	Y	V	P	A	P	F	C	K	D	S	I	L	E	A	I	D	A	G	I	K	L	I	I	T	I	T	E	G	I	P	T	L	D	M	L	T	V	K	V	K	L	D	E	A	G	V	R	M	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	P	N	C	P	G	V	I	T	P	G	E	C	K	I	G	I	Q	P	G	H	I	H	K	P	G	K	V	G	I	V	S	R	S	G	T	L	T	Y	E	A	V	K	Q	T	T	D	Y	G	F	G	Q	S	T	C	V	G	I	G	G
Secondary structure
SS confidence
Disorder																				?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		D	P	I	P	G	S	N	F	I	D	I	L	E	M	F	E	K	D	P	Q	T	E	A	I	V	M	I	G	E	I	G	G	S	A	E	E	E	A	A	A	Y	I	K	E	H	V	T	K	P	V	V	G	Y	I	A	G	V	T	A	P
Secondary structure
SS confidence
Disorder																																																													?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.
Sequence		K	G	K	R	M	G	H	A	G	A	I	I	A	G	G	K	G	T	A	D	E	K	F	A	A	L	E	A	A	G	V	K	T	V	R	S	L	A	D	I	G	E	A	L	K	T	V	L	K
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?																																		?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2nu8 chain D Region: 2 - 288 Aligned: 287 Modelled: 287 Confidence: 100.0% Identity: 100% PDB header:ligase Chain: D: PDB Molecule:succinyl-coa ligase [adp-forming] subunit alpha; PDBTitle: c123at mutant of e. coli succinyl-coa synthetase Phyre2 PDB 2fpg chain A Region: 2 - 289 Aligned: 288 Modelled: 288 Confidence: 100.0% Identity: 64% PDB header:ligase Chain: A: PDB Molecule:succinyl-coa ligase [gdp-forming] alpha-chain, PDBTitle: crystal structure of pig gtp-specific succinyl-coa2 synthetase in complex with gdp Phyre2 PDB 2yv2 chain A Region: 4 - 288 Aligned: 267 Modelled: 267 Confidence: 100.0% Identity: 51% PDB header:ligase Chain: A: PDB Molecule:succinyl-coa synthetase alpha chain; PDBTitle: crystal structure of succinyl-coa synthetase alpha chain from2 aeropyrum pernix k1 Phyre2 PDB 1oi7 chain A Region: 3 - 288 Aligned: 268 Modelled: 268 Confidence: 100.0% Identity: 54% PDB header:synthetase Chain: A: PDB Molecule:succinyl-coa synthetase alpha chain; PDBTitle: the crystal structure of succinyl-coa synthetase alpha2 subunit from thermus thermophilus Phyre2 PDB 3mwd chain B Region: 2 - 282 Aligned: 277 Modelled: 281 Confidence: 100.0% Identity: 29% PDB header:transferase Chain: B: PDB Molecule:atp-citrate synthase; PDBTitle: truncated human atp-citrate lyase with citrate bound Phyre2 PDB 2yv1 chain A Region: 3 - 272 Aligned: 265 Modelled: 263 Confidence: 100.0% Identity: 54% PDB header:ligase Chain: A: PDB Molecule:succinyl-coa ligase [adp-forming] subunit alpha; PDBTitle: crystal structure of succinyl-coa synthetase alpha chain from2 methanocaldococcus jannaschii dsm 2661 Phyre2 PDB 2csu chain B Region: 1 - 287 Aligned: 257 Modelled: 260 Confidence: 100.0% Identity: 21% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:457aa long hypothetical protein; PDBTitle: crystal structure of ph0766 from pyrococcus horikoshii ot3 Phyre2 PDB 3dmy chain A Region: 48 - 275 Aligned: 218 Modelled: 216 Confidence: 100.0% Identity: 17% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:protein fdra; PDBTitle: crystal structure of a predicated acyl-coa synthetase from e.coli Phyre2 PDB 1euc chain A domain 2 Region: 123 - 289 Aligned: 167 Modelled: 167 Confidence: 100.0% Identity: 63% Fold: Flavodoxin-like Superfamily: Succinyl-CoA synthetase domains Family: Succinyl-CoA synthetase domains Phyre2 PDB 2nu7 chain A domain 2 Region: 123 - 288 Aligned: 166 Modelled: 166 Confidence: 100.0% Identity: 99% Fold: Flavodoxin-like Superfamily: Succinyl-CoA synthetase domains Family: Succinyl-CoA synthetase domains Phyre2 PDB 1oi7 chain A domain 2 Region: 123 - 288 Aligned: 148 Modelled: 148 Confidence: 100.0% Identity: 55% Fold: Flavodoxin-like Superfamily: Succinyl-CoA synthetase domains Family: Succinyl-CoA synthetase domains Phyre2 PDB 2csu chain A domain 2 Region: 125 - 287 Aligned: 139 Modelled: 142 Confidence: 100.0% Identity: 21% Fold: Flavodoxin-like Superfamily: Succinyl-CoA synthetase domains Family: Succinyl-CoA synthetase domains Phyre2 PDB 2csu chain A domain 1 Region: 1 - 124 Aligned: 119 Modelled: 124 Confidence: 100.0% Identity: 21% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: CoA-binding domain Phyre2 PDB 2duw chain A Region: 1 - 134 Aligned: 127 Modelled: 134 Confidence: 99.9% Identity: 18% PDB header:ligand binding protein Chain: A: PDB Molecule:putative coa-binding protein; PDBTitle: solution structure of putative coa-binding protein of2 klebsiella pneumoniae Phyre2 PDB 1euc chain A domain 1 Region: 2 - 122 Aligned: 121 Modelled: 121 Confidence: 99.9% Identity: 65% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: CoA-binding domain Phyre2 PDB 1iuk chain A Region: 2 - 130 Aligned: 121 Modelled: 129 Confidence: 99.9% Identity: 16% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: CoA-binding domain Phyre2 PDB 2nu7 chain A domain 1 Region: 3 - 121 Aligned: 119 Modelled: 119 Confidence: 99.9% Identity: 100% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: CoA-binding domain Phyre2 PDB 2d59 chain A domain 1 Region: 3 - 127 Aligned: 115 Modelled: 125 Confidence: 99.9% Identity: 18% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: CoA-binding domain Phyre2 PDB 1y81 chain A domain 1 Region: 10 - 127 Aligned: 109 Modelled: 116 Confidence: 99.9% Identity: 23% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: CoA-binding domain Phyre2 PDB 1oi7 chain A domain 1 Region: 3 - 121 Aligned: 119 Modelled: 119 Confidence: 99.9% Identity: 55% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: CoA-binding domain Phyre2 1 c2nu8D_ 2 c2fpgA_ 3 c2yv2A_ 4 c1oi7A_ 5 c3mwdB_ 6 c2yv1A_ 7 c2csuB_ 8 c3dmyA_ 9 d1euca2 10 d2nu7a2 11 d1oi7a2 12 d2csua2 13 d2csua1 14 c2duwA_ 15 d1euca1 16 d1iuka_ 17 d2nu7a1 18 d2d59a1 19 d1y81a1 20 d1oi7a1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499