Secondary structure and disorder prediction

1

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10

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20

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30

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40

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50

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60

Sequence

M

A

R

I

N

R

I

S

I

T

L

C

A

L

L

F

T

T

L

P

L

T

P

M

A

H

A

S

K

Q

A

R

E

S

S

A

T

T

H

I

T

K

K

A

D

K

K

K

S

T

A

T

T

K

K

T

Q

K

T

A

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

Disorder confidence

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70

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80

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90

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100

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110

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.

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120

Sequence

K

K

A

A

S

K

S

T

T

K

S

K

T

A

S

S

V

K

K

S

S

I

T

A

S

K

N

A

K

T

R

S

K

H

A

V

N

K

T

A

S

A

S

F

T

E

K

C

T

K

R

K

G

Y

K

S

H

C

V

K

Secondary structure

SS confidence

Disorder

?

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?

Disorder confidence

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130

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140

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150

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160

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170

.

.

.

.

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.

.

.

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180

Sequence

V

K

N

A

A

S

G

T

L

A

D

A

H

K

A

K

V

Q

K

A

T

K

V

A

M

N

K

L

M

Q

Q

I

G

K

P

Y

R

W

G

G

S

S

P

R

T

G

F

D

C

S

G

L

V

Y

Y

A

Y

K

D

L

Secondary structure

SS confidence

Disorder

?

?

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?

?

?

?

?

?

?

Disorder confidence

.

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190

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200

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210

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220

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230

.

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.

.

.

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.

.

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240

Sequence

V

K

I

R

I

P

R

T

A

N

E

M

Y

H

L

R

D

A

A

P

I

E

R

S

E

L

K

N

G

D

L

V

F

F

R

T

Q

G

R

G

T

A

D

H

V

G

V

Y

V

G

N

G

K

F

I

Q

S

P

R

T

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

?

?

Disorder confidence

.

.

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250

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.

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260

.

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.

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.

.

270

.

Sequence

G

Q

E

I

Q

I

T

S

L

S

E

D

Y

W

Q

R

H

Y

V

G

A

R

R

V

M

T

P

K

T

L

R

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2fg0 chain B Region: 121 - 265 Aligned: 139 Modelled: 145 Confidence: 100.0% Identity: 34% PDB header:hydrolase Chain: B: PDB Molecule:cog0791: cell wall-associated hydrolases (invasion- PDBTitle: crystal structure of a putative gamma-d-glutamyl-l-diamino acid2 endopeptidase (npun_r0659) from nostoc punctiforme pcc 73102 at 1.793 a resolution Phyre2 PDB 2xiv chain A Region: 95 - 265 Aligned: 162 Modelled: 171 Confidence: 100.0% Identity: 27% PDB header:structural protein Chain: A: PDB Molecule:hypothetical invasion protein; PDBTitle: structure of rv1477, hypothetical invasion protein of2 mycobacterium tuberculosis Phyre2 PDB 2evr chain A domain 2 Region: 138 - 269 Aligned: 126 Modelled: 132 Confidence: 100.0% Identity: 37% Fold: Cysteine proteinases Superfamily: Cysteine proteinases Family: NlpC/P60 Phyre2 PDB 3h41 chain A Region: 131 - 265 Aligned: 130 Modelled: 135 Confidence: 100.0% Identity: 34% PDB header:hydrolase Chain: A: PDB Molecule:nlp/p60 family protein; PDBTitle: crystal structure of a nlpc/p60 family protein (bce_2878) from2 bacillus cereus atcc 10987 at 1.79 a resolution Phyre2 PDB 3npf chain B Region: 136 - 268 Aligned: 125 Modelled: 133 Confidence: 100.0% Identity: 30% PDB header:hydrolase Chain: B: PDB Molecule:putative dipeptidyl-peptidase vi; PDBTitle: crystal structure of a putative dipeptidyl-peptidase vi (bacova_00612)2 from bacteroides ovatus at 1.72 a resolution Phyre2 PDB 3pbi chain A Region: 119 - 265 Aligned: 138 Modelled: 145 Confidence: 100.0% Identity: 30% PDB header:hydrolase Chain: A: PDB Molecule:invasion protein; PDBTitle: structure of the peptidoglycan hydrolase ripb (rv1478) from2 mycobacterium tuberculosis at 1.6 resolution Phyre2 PDB 2k1g chain A Region: 137 - 268 Aligned: 126 Modelled: 132 Confidence: 100.0% Identity: 35% PDB header:lipoprotein Chain: A: PDB Molecule:lipoprotein spr; PDBTitle: solution nmr structure of lipoprotein spr from escherichia coli k12.2 northeast structural genomics target er541-37-162 Phyre2 PDB 3gt2 chain A Region: 138 - 265 Aligned: 116 Modelled: 128 Confidence: 100.0% Identity: 34% PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of the p60 domain from m. avium2 paratuberculosis antigen map1272c Phyre2 PDB 3i86 chain A Region: 138 - 265 Aligned: 119 Modelled: 126 Confidence: 100.0% Identity: 32% PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of the p60 domain from m. avium subspecies2 paratuberculosis antigen map1204 Phyre2 PDB 3m1u chain B Region: 141 - 267 Aligned: 109 Modelled: 127 Confidence: 99.8% Identity: 21% PDB header:hydrolase Chain: B: PDB Molecule:putative gamma-d-glutamyl-l-diamino acid endopeptidase; PDBTitle: crystal structure of a putative gamma-d-glutamyl-l-diamino acid2 endopeptidase (dvu_0896) from desulfovibrio vulgaris hildenborough at3 1.75 a resolution Phyre2 PDB 2p1g chain A Region: 144 - 265 Aligned: 121 Modelled: 122 Confidence: 99.6% Identity: 22% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative xylanase; PDBTitle: crystal structure of a putative xylanase from bacteroides fragilis Phyre2 PDB 2kyt chain A Region: 200 - 258 Aligned: 56 Modelled: 59 Confidence: 98.1% Identity: 23% PDB header:hydrolase Chain: A: PDB Molecule:group xvi phospholipase a2; PDBTitle: solution struture of the h-rev107 n-terminal domain Phyre2 PDB 3kw0 chain D Region: 203 - 249 Aligned: 46 Modelled: 47 Confidence: 98.0% Identity: 24% PDB header:hydrolase Chain: D: PDB Molecule:cysteine peptidase; PDBTitle: crystal structure of cysteine peptidase (np_982244.1) from bacillus2 cereus atcc 10987 at 2.50 a resolution Phyre2 PDB 2if6 chain A domain 1 Region: 134 - 188 Aligned: 55 Modelled: 55 Confidence: 97.3% Identity: 18% Fold: Cysteine proteinases Superfamily: Cysteine proteinases Family: YiiX-like Phyre2 PDB 2k3a chain A Region: 169 - 271 Aligned: 86 Modelled: 103 Confidence: 93.3% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:chap domain protein; PDBTitle: nmr solution structure of staphylococcus saprophyticus chap2 (cysteine, histidine-dependent amidohydrolases/peptidases)3 domain protein. northeast structural genomics consortium4 target syr11 Phyre2 PDB 2im9 chain A Region: 203 - 249 Aligned: 47 Modelled: 47 Confidence: 91.8% Identity: 23% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein; PDBTitle: crystal structure of protein lpg0564 from legionella pneumophila str.2 philadelphia 1, pfam duf1460 Phyre2 PDB 2im9 chain A domain 1 Region: 203 - 249 Aligned: 47 Modelled: 47 Confidence: 91.8% Identity: 23% Fold: Cysteine proteinases Superfamily: Cysteine proteinases Family: Lpg0564-like Phyre2 PDB 2io8 chain A domain 2 Region: 207 - 230 Aligned: 24 Modelled: 24 Confidence: 87.8% Identity: 21% Fold: Cysteine proteinases Superfamily: Cysteine proteinases Family: CHAP domain Phyre2 PDB 2ar1 chain A domain 1 Region: 203 - 227 Aligned: 25 Modelled: 25 Confidence: 85.2% Identity: 20% Fold: PUA domain-like Superfamily: PUA domain-like Family: Atu2648/PH1033-like Phyre2 PDB 2g2x chain A domain 1 Region: 205 - 227 Aligned: 23 Modelled: 23 Confidence: 83.8% Identity: 22% Fold: PUA domain-like Superfamily: PUA domain-like Family: Atu2648/PH1033-like Phyre2 1 c2fg0B_ 2 c2xivA_ 3 d2evra2 4 c3h41A_ 5 c3npfB_ 6 c3pbiA_ 7 c2k1gA_ 8 c3gt2A_ 9 c3i86A_ 10 c3m1uB_ 11 c2p1gA_ 12 c2kytA_ 13 c3kw0D_ 14 d2if6a1 15 c2k3aA_ 16 c2im9A_ 17 d2im9a1 18 d2io8a2 19 d2ar1a1 20 d2g2xa1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2fg0B_ 100.0 34 PDB header:hydrolase Chain: B: PDB Molecule:cog0791: cell wall-associated hydrolases (invasion- PDBTitle: crystal structure of a putative gamma-d-glutamyl-l-diamino acid2 endopeptidase (npun_r0659) from nostoc punctiforme pcc 73102 at 1.793 a resolution 2 c2xivA_ 100.0 27 PDB header:structural protein Chain: A: PDB Molecule:hypothetical invasion protein; PDBTitle: structure of rv1477, hypothetical invasion protein of2 mycobacterium tuberculosis 3 d2evra2 100.0 37 Fold:Cysteine proteinases Superfamily:Cysteine proteinases Family:NlpC/P60 4 c3h41A_ 100.0 34 PDB header:hydrolase Chain: A: PDB Molecule:nlp/p60 family protein; PDBTitle: crystal structure of a nlpc/p60 family protein (bce_2878) from2 bacillus cereus atcc 10987 at 1.79 a resolution 5 c3npfB_ 100.0 30 PDB header:hydrolase Chain: B: PDB Molecule:putative dipeptidyl-peptidase vi; PDBTitle: crystal structure of a putative dipeptidyl-peptidase vi (bacova_00612)2 from bacteroides ovatus at 1.72 a resolution 6 c3pbiA_ 100.0 30 PDB header:hydrolase Chain: A: PDB Molecule:invasion protein; PDBTitle: structure of the peptidoglycan hydrolase ripb (rv1478) from2 mycobacterium tuberculosis at 1.6 resolution 7 c2k1gA_ 100.0 35 PDB header:lipoprotein Chain: A: PDB Molecule:lipoprotein spr; PDBTitle: solution nmr structure of lipoprotein spr from escherichia coli k12.2 northeast structural genomics target er541-37-162 8 c3gt2A_ 100.0 34 PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of the p60 domain from m. avium2 paratuberculosis antigen map1272c 9 c3i86A_ 100.0 32 PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of the p60 domain from m. avium subspecies2 paratuberculosis antigen map1204 10 c3m1uB_ 99.8 21 PDB header:hydrolase Chain: B: PDB Molecule:putative gamma-d-glutamyl-l-diamino acid endopeptidase; PDBTitle: crystal structure of a putative gamma-d-glutamyl-l-diamino acid2 endopeptidase (dvu_0896) from desulfovibrio vulgaris hildenborough at3 1.75 a resolution 11 c2p1gA_ 99.6 22 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative xylanase; PDBTitle: crystal structure of a putative xylanase from bacteroides fragilis 12 c2kytA_ 98.1 23 PDB header:hydrolase Chain: A: PDB Molecule:group xvi phospholipase a2; PDBTitle: solution struture of the h-rev107 n-terminal domain 13 c3kw0D_ 98.0 24 PDB header:hydrolase Chain: D: PDB Molecule:cysteine peptidase; PDBTitle: crystal structure of cysteine peptidase (np_982244.1) from bacillus2 cereus atcc 10987 at 2.50 a resolution 14 d2if6a1 97.3 18 Fold:Cysteine proteinases Superfamily:Cysteine proteinases Family:YiiX-like 15 c2k3aA_ 93.3 15 PDB header:hydrolase Chain: A: PDB Molecule:chap domain protein; PDBTitle: nmr solution structure of staphylococcus saprophyticus chap2 (cysteine, histidine-dependent amidohydrolases/peptidases)3 domain protein. northeast structural genomics consortium4 target syr11 16 c2im9A_ 91.8 23 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein; PDBTitle: crystal structure of protein lpg0564 from legionella pneumophila str.2 philadelphia 1, pfam duf1460 17 d2im9a1 91.8 23 Fold:Cysteine proteinases Superfamily:Cysteine proteinases Family:Lpg0564-like 18 d2io8a2 87.8 21 Fold:Cysteine proteinases Superfamily:Cysteine proteinases Family:CHAP domain 19 d2ar1a1 85.2 20 Fold:PUA domain-like Superfamily:PUA domain-like Family:Atu2648/PH1033-like 20 d2g2xa1 83.8 22 Fold:PUA domain-like Superfamily:PUA domain-like Family:Atu2648/PH1033-like 21 d2gbsa1 not modelled 83.7 21 Fold:PUA domain-like Superfamily:PUA domain-like Family:Atu2648/PH1033-like 22 d1zcea1 not modelled 83.1 38 Fold:PUA domain-like Superfamily:PUA domain-like Family:Atu2648/PH1033-like 23 c3eopB_ not modelled 82.7 22 PDB header:unknown function Chain: B: PDB Molecule:thymocyte nuclear protein 1; PDBTitle: crystal structure of the duf55 domain of human thymocyte nuclear2 protein 1 24 d2evea1 not modelled 82.3 20 Fold:PUA domain-like Superfamily:PUA domain-like Family:Atu2648/PH1033-like 25 c2vpmB_ not modelled 75.4 17 PDB header:ligase Chain: B: PDB Molecule:trypanothione synthetase; PDBTitle: trypanothione synthetase 26 c3kopB_ not modelled 74.3 23 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of protein with a cyclophilin-like fold2 (yp_831253.1) from arthrobacter sp. fb24 at 1.90 a resolution 27 c3nnlB_ not modelled 66.3 27 PDB header:biosynthetic protein Chain: B: PDB Molecule:cura; PDBTitle: halogenase domain from cura module (crystal form iii) 28 c2ioaA_ not modelled 65.3 21 PDB header:ligase, hydrolase Chain: A: PDB Molecule:bifunctional glutathionylspermidine PDBTitle: e. coli bifunctional glutathionylspermidine2 synthetase/amidase incomplex with mg2+ and adp and3 phosphinate inhibitor 29 d2eyqa1 not modelled 65.2 35 Fold:SH3-like barrel Superfamily:CarD-like Family:CarD-like 30 c2wbqA_ not modelled 64.3 36 PDB header:oxidoreductase Chain: A: PDB Molecule:l-arginine beta-hydroxylase; PDBTitle: crystal structure of vioc in complex with (2s,3s)-2 hydroxyarginine 31 c1i7oC_ not modelled 62.7 27 PDB header:isomerase, lyase Chain: C: PDB Molecule:4-hydroxyphenylacetate degradation bifunctional PDBTitle: crystal structure of hpce 32 d1jr7a_ not modelled 62.4 8 Fold:Double-stranded beta-helix Superfamily:Clavaminate synthase-like Family:Gab protein (hypothetical protein YgaT) 33 d1wpga1 not modelled 59.7 21 Fold:Double-stranded beta-helix Superfamily:Calcium ATPase, transduction domain A Family:Calcium ATPase, transduction domain A 34 d1ds1a_ not modelled 57.5 36 Fold:Double-stranded beta-helix Superfamily:Clavaminate synthase-like Family:Clavaminate synthase 35 c2og5A_ not modelled 57.3 27 PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxygenase; PDBTitle: crystal structure of asparagine oxygenase (asno) 36 d2ba0a2 not modelled 55.1 28 Fold:Barrel-sandwich hybrid Superfamily:Ribosomal L27 protein-like Family:ECR1 N-terminal domain-like 37 d1otja_ not modelled 54.4 12 Fold:Double-stranded beta-helix Superfamily:Clavaminate synthase-like Family:TauD/TfdA-like 38 d2fcta1 not modelled 53.6 15 Fold:Double-stranded beta-helix Superfamily:Clavaminate synthase-like Family:PhyH-like 39 c3r1jB_ not modelled 50.5 18 PDB header:oxidoreductase Chain: B: PDB Molecule:alpha-ketoglutarate-dependent taurine dioxygenase; PDBTitle: crystal structure of alpha-ketoglutarate-dependent taurine dioxygenase2 from mycobacterium avium, native form 40 d1nx4a_ not modelled 49.8 27 Fold:Double-stranded beta-helix Superfamily:Clavaminate synthase-like Family:gamma-Butyrobetaine hydroxylase 41 c3eatX_ not modelled 49.6 25 PDB header:oxidoreductase Chain: X: PDB Molecule:pyoverdine biosynthesis protein pvcb; PDBTitle: crystal structure of the pvcb (pa2255) protein from2 pseudomonas aeruginosa 42 c3pvjB_ not modelled 48.6 18 PDB header:oxidoreductase Chain: B: PDB Molecule:alpha-ketoglutarate-dependent taurine dioxygenase; PDBTitle: crystal structure of the fe(ii)/alpha-ketoglutarate dependent taurine2 dioxygenase from pseudomonas putida kt2440 43 d1oiha_ not modelled 48.2 18 Fold:Double-stranded beta-helix Superfamily:Clavaminate synthase-like Family:TauD/TfdA-like 44 d1o6aa_ not modelled 47.5 15 Fold:Surface presentation of antigens (SPOA) Superfamily:Surface presentation of antigens (SPOA) Family:Surface presentation of antigens (SPOA) 45 c2q1dX_ not modelled 46.8 21 PDB header:lyase Chain: X: PDB Molecule:2-keto-3-deoxy-d-arabinonate dehydratase; PDBTitle: 2-keto-3-deoxy-d-arabinonate dehydratase complexed with magnesium and2 2,5-dioxopentanoate 46 d1zx8a1 not modelled 44.7 25 Fold:Cyclophilin-like Superfamily:Cyclophilin-like Family:TM1367-like 47 c2nnzA_ not modelled 44.3 20 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein; PDBTitle: solution structure of the hypothetical protein af2241 from2 archaeoglobus fulgidus 48 c3b8eC_ not modelled 44.0 27 PDB header:hydrolase/transport protein Chain: C: PDB Molecule:sodium/potassium-transporting atpase subunit PDBTitle: crystal structure of the sodium-potassium pump 49 d1o9ya_ not modelled 43.8 18 Fold:Surface presentation of antigens (SPOA) Superfamily:Surface presentation of antigens (SPOA) Family:Surface presentation of antigens (SPOA) 50 d1y0za_ not modelled 42.0 18 Fold:Double-stranded beta-helix Superfamily:Clavaminate synthase-like Family:gamma-Butyrobetaine hydroxylase 51 c2eyqA_ not modelled 41.9 35 PDB header:hydrolase Chain: A: PDB Molecule:transcription-repair coupling factor; PDBTitle: crystal structure of escherichia coli transcription-repair2 coupling factor 52 c3ms5A_ not modelled 41.9 27 PDB header:oxidoreductase Chain: A: PDB Molecule:gamma-butyrobetaine dioxygenase; PDBTitle: crystal structure of human gamma-butyrobetaine,2-oxoglutarate2 dioxygenase 1 (bbox1) 53 d1c0aa2 not modelled 41.3 40 Fold:DCoH-like Superfamily:GAD domain-like Family:GAD domain 54 c2hc8A_ not modelled 41.2 22 PDB header:transport protein Chain: A: PDB Molecule:cation-transporting atpase, p-type; PDBTitle: structure of the a. fulgidus copa a-domain 55 c2kijA_ not modelled 41.1 19 PDB header:hydrolase Chain: A: PDB Molecule:copper-transporting atpase 1; PDBTitle: solution structure of the actuator domain of the copper-2 transporting atpase atp7a 56 d1nkqa_ not modelled 40.4 24 Fold:FAH Superfamily:FAH Family:FAH 57 d2z1ea2 not modelled 40.1 31 Fold:PurM C-terminal domain-like Superfamily:PurM C-terminal domain-like Family:PurM C-terminal domain-like 58 d1l0wa2 not modelled 39.8 40 Fold:DCoH-like Superfamily:GAD domain-like Family:GAD domain 59 c2dbiA_ not modelled 38.8 25 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein ybiu; PDBTitle: crystal structure of a hypothetical protein jw0805 from2 escherichia coli 60 c3qdfA_ not modelled 38.7 29 PDB header:isomerase Chain: A: PDB Molecule:2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; PDBTitle: crystal structure of 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase2 from mycobacterium marinum 61 d2csga1 not modelled 38.3 25 Fold:Double-stranded beta-helix Superfamily:Clavaminate synthase-like Family:YbiU-like 62 c3b9bA_ not modelled 37.5 20 PDB header:hydrolase Chain: A: PDB Molecule:sarcoplasmic/endoplasmic reticulum calcium PDBTitle: structure of the e2 beryllium fluoride complex of the serca2 ca2+-atpase 63 d2jfga2 not modelled 37.2 17 Fold:MurD-like peptide ligases, peptide-binding domain Superfamily:MurD-like peptide ligases, peptide-binding domain Family:MurCDEF C-terminal domain 64 c2x35A_ not modelled 37.0 50 PDB header:transcription Chain: A: PDB Molecule:peregrin; PDBTitle: molecular basis of histone h3k36me3 recognition by the pwwp2 domain of brpf1. 65 d1hyoa2 not modelled 36.8 41 Fold:FAH Superfamily:FAH Family:FAH 66 c2opwA_ not modelled 36.8 27 PDB header:oxidoreductase Chain: A: PDB Molecule:phyhd1 protein; PDBTitle: crystal structure of human phytanoyl-coa dioxygenase phyhd1 (apo) 67 c3d79A_ not modelled 36.0 21 PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein ph0734; PDBTitle: crystal structure of hypothetical protein ph0734.1 from2 hyperthermophilic archaea pyrococcus horikoshii ot3 68 c2zxeA_ not modelled 33.5 23 PDB header:hydrolase/transport protein Chain: A: PDB Molecule:na, k-atpase alpha subunit; PDBTitle: crystal structure of the sodium - potassium pump in the e2.2k+.pi2 state 69 d1wida_ not modelled 33.5 26 Fold:DNA-binding pseudobarrel domain Superfamily:DNA-binding pseudobarrel domain Family:B3 DNA binding domain 70 d1we3o_ not modelled 32.8 31 Fold:GroES-like Superfamily:GroES-like Family:GroES 71 c3lzkC_ not modelled 32.4 23 PDB header:hydrolase Chain: C: PDB Molecule:fumarylacetoacetate hydrolase family protein; PDBTitle: the crystal structure of a probably aromatic amino acid2 degradation protein from sinorhizobium meliloti 1021 72 c1yy3A_ not modelled 31.9 15 PDB header:isomerase Chain: A: PDB Molecule:s-adenosylmethionine:trna ribosyltransferase- PDBTitle: structure of s-adenosylmethionine:trna ribosyltransferase-2 isomerase (quea) 73 c3emrA_ not modelled 31.9 30 PDB header:oxidoreductase Chain: A: PDB Molecule:ectd; PDBTitle: crystal structure analysis of the ectoine hydroxylase ectd from2 salibacillus salexigens 74 d1p3ha_ not modelled 31.8 24 Fold:GroES-like Superfamily:GroES-like Family:GroES 75 c1mhsA_ not modelled 31.8 22 PDB header:membrane protein, proton transport Chain: A: PDB Molecule:plasma membrane atpase; PDBTitle: model of neurospora crassa proton atpase 76 d2zoda2 not modelled 31.4 31 Fold:PurM C-terminal domain-like Superfamily:PurM C-terminal domain-like Family:PurM C-terminal domain-like 77 c3r6oA_ not modelled 31.3 20 PDB header:isomerase Chain: A: PDB Molecule:2-hydroxyhepta-2,4-diene-1, 7-dioateisomerase; PDBTitle: crystal structure of a probable 2-hydroxyhepta-2,4-diene-1, 7-2 dioateisomerase from mycobacterium abscessus 78 d1knwa1 not modelled 30.8 26 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like Superfamily:Alanine racemase C-terminal domain-like Family:Eukaryotic ODC-like 79 c2rdsA_ not modelled 30.7 30 PDB header:oxidoreductase Chain: A: PDB Molecule:1-deoxypentalenic acid 11-beta hydroxylase; fe(ii)/alpha- PDBTitle: crystal structure of ptlh with fe/oxalylglycine and ent-1-2 deoxypentalenic acid bound 80 c3ixzA_ not modelled 29.4 30 PDB header:hydrolase Chain: A: PDB Molecule:potassium-transporting atpase alpha; PDBTitle: pig gastric h+/k+-atpase complexed with aluminium fluoride 81 c2de0X_ not modelled 28.5 21 PDB header:transferase Chain: X: PDB Molecule:alpha-(1,6)-fucosyltransferase; PDBTitle: crystal structure of human alpha 1,6-fucosyltransferase, fut8 82 d2a1xa1 not modelled 28.5 45 Fold:Double-stranded beta-helix Superfamily:Clavaminate synthase-like Family:PhyH-like 83 c3gjbA_ not modelled 28.4 50 PDB header:biosynthetic protein Chain: A: PDB Molecule:cytc3; PDBTitle: cytc3 with fe(ii) and alpha-ketoglutarate 84 c1wzoC_ not modelled 28.2 21 PDB header:isomerase Chain: C: PDB Molecule:hpce; PDBTitle: crystal structure of the hpce from thermus thermophilus hb8 85 d1njjb1 not modelled 27.6 29 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like Superfamily:Alanine racemase C-terminal domain-like Family:Eukaryotic ODC-like 86 d1vkya_ not modelled 27.6 33 Fold:QueA-like Superfamily:QueA-like Family:QueA-like 87 c3j09A_ not modelled 27.3 21 PDB header:hydrolase, metal transport Chain: A: PDB Molecule:copper-exporting p-type atpase a; PDBTitle: high resolution helical reconstruction of the bacterial p-type atpase2 copper transporter copa 88 d1aono_ not modelled 26.8 26 Fold:GroES-like Superfamily:GroES-like Family:GroES 89 c2l8kA_ not modelled 26.6 22 PDB header:viral protein Chain: A: PDB Molecule:non-structural protein 7; PDBTitle: nmr structure of the arterivirus nonstructural protein 7 alpha (nsp72 alpha) 90 c3ibmB_ not modelled 25.6 22 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:cupin 2, conserved barrel domain protein; PDBTitle: crystal structure of cupin 2 domain-containing protein hhal_0468 from2 halorhodospira halophila 91 d2ja9a1 not modelled 25.3 41 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 92 c2qf4A_ not modelled 25.0 33 PDB header:structural protein Chain: A: PDB Molecule:cell shape determining protein mrec; PDBTitle: high resolution structure of the major periplasmic domain from the2 cell shape-determining filament mrec (orthorhombic form) 93 d1hkva1 not modelled 24.9 36 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like Superfamily:Alanine racemase C-terminal domain-like Family:Eukaryotic ODC-like 94 c3es4B_ not modelled 24.6 24 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein duf861 with a rmlc-like cupin fold; PDBTitle: crystal structure of protein of unknown function (duf861) with a rmlc-2 like cupin fold (17741406) from agrobacterium tumefaciens str. c583 (dupont) at 1.64 a resolution 95 d1y71a1 not modelled 24.4 39 Fold:SH3-like barrel Superfamily:Kinase-associated protein B-like Family:Kinase-associated protein B-like 96 c3j08A_ not modelled 24.4 21 PDB header:hydrolase, metal transport Chain: A: PDB Molecule:copper-exporting p-type atpase a; PDBTitle: high resolution helical reconstruction of the bacterial p-type atpase2 copper transporter copa 97 d1wdia_ not modelled 24.3 29 Fold:QueA-like Superfamily:QueA-like Family:QueA-like 98 d1twia1 not modelled 23.9 21 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like Superfamily:Alanine racemase C-terminal domain-like Family:Eukaryotic ODC-like 99 c2xxzA_ not modelled 23.7 31 PDB header:oxidoreductase Chain: A: PDB Molecule:lysine-specific demethylase 6b; PDBTitle: crystal structure of the human jmjd3 jumonji domain 100 d3c9ua2 not modelled 23.2 33 Fold:PurM C-terminal domain-like Superfamily:PurM C-terminal domain-like Family:PurM C-terminal domain-like 101 d2caya1 not modelled 23.2 35 Fold:PH domain-like barrel Superfamily:PH domain-like Family:VPS36 N-terminal domain-like 102 c3anuA_ not modelled 23.2 15 PDB header:lyase Chain: A: PDB Molecule:d-serine dehydratase; PDBTitle: crystal structure of d-serine dehydratase from chicken kidney 103 d1s04a_ not modelled 23.0 36 Fold:PUA domain-like Superfamily:PUA domain-like Family:ProFAR isomerase associated domain 104 c3lyiA_ not modelled 22.9 14 PDB header:transcription Chain: A: PDB Molecule:bromodomain-containing protein 1; PDBTitle: pwwp domain of human bromodomain-containing protein 1 105 d1xnea_ not modelled 22.9 29 Fold:PUA domain-like Superfamily:PUA domain-like Family:ProFAR isomerase associated domain 106 d1a3xa1 not modelled 22.5 7 Fold:PK beta-barrel domain-like Superfamily:PK beta-barrel domain-like Family:Pyruvate kinase beta-barrel domain 107 c2nn6H_ not modelled 22.3 33 PDB header:hydrolase/transferase Chain: H: PDB Molecule:exosome complex exonuclease rrp4; PDBTitle: structure of the human rna exosome composed of rrp41, rrp45,2 rrp46, rrp43, mtr3, rrp42, csl4, rrp4, and rrp40 108 c3tu8A_ not modelled 21.9 41 PDB header:unknown function Chain: A: PDB Molecule:burkholderia lethal factor 1 (blf1); PDBTitle: crystal structure of the burkholderia lethal factor 1 (blf1) 109 d1f3ta1 not modelled 21.8 29 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like Superfamily:Alanine racemase C-terminal domain-like Family:Eukaryotic ODC-like 110 d2toda1 not modelled 21.7 31 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like Superfamily:Alanine racemase C-terminal domain-like Family:Eukaryotic ODC-like 111 d7odca1 not modelled 21.2 36 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like Superfamily:Alanine racemase C-terminal domain-like Family:Eukaryotic ODC-like 112 d1clia2 not modelled 21.2 27 Fold:PurM C-terminal domain-like Superfamily:PurM C-terminal domain-like Family:PurM C-terminal domain-like 113 c2dfuB_ not modelled 20.8 29 PDB header:isomerase Chain: B: PDB Molecule:probable 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; PDBTitle: crystal structure of the 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase2 from thermus thermophilus hb8 114 c2p5dA_ not modelled 20.7 22 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0310 protein mjecl36; PDBTitle: crystal structure of mjecl36 from methanocaldococcus2 jannaschii dsm 2661 115 c3rfuC_ not modelled 20.5 18 PDB header:hydrolase, membrane protein Chain: C: PDB Molecule:copper efflux atpase; PDBTitle: crystal structure of a copper-transporting pib-type atpase 116 d2grea1 not modelled 20.5 31 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like Superfamily:Aminopeptidase/glucanase lid domain Family:Aminopeptidase/glucanase lid domain 117 c3l53F_ not modelled 20.3 35 PDB header:structural genomics, unknown function Chain: F: PDB Molecule:putative fumarylacetoacetate isomerase/hydrolase; PDBTitle: crystal structure of a putative fumarylacetoacetate2 isomerase/hydrolase from oleispira antarctica

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0