Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP75864
DateThu Jan 5 12:15:14 GMT 2012
Unique Job ID12142e5c99d436e6

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3lduA_
Top template information
PDB header:transferase
Chain: A: PDB Molecule:putative methylase;
PDBTitle: the crystal structure of a possible methylase from2 clostridium difficile 630.
Confidence and coverage
Confidence:100.0% Coverage: 53%
374 residues ( 53% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
681 residues ( 97%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MNSLFASTARGLEELLKTELENLGAVECQVVQGGVHFKGDTRLVYQSLMWSRLASRIMLP
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Disorder  ???
























??





























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   .........70.........80.........90.........100.........110.........120
Sequence  LGECKVYSDLDLYLGVQAINWTEMFNPGATFAVHFSGLNDTIRNSQYGAMKVKDAIVDAF
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   .........130.........140.........150.........160.........170.........180
Sequence  TRKNLPRPNVDRDAPDIRVNVWLHKETASIALDLSGDGLHLRGYRDRAGIAPIKETLAAA
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Disorder 




?



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?
???????








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   .........190.........200.........210.........220.........230.........240
Sequence  IVMRSGWQPGTPLLDPMCGSGTLLIEAAMLATDRAPGLHRGRWGFSGWAQHDEAIWQEVK
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   .........250.........260.........270.........280.........290.........300
Sequence  AEAQTRARKGLAEYSSHFYGSDSDARVIQRARTNARLAGIGELITFEVKDVAQLTNPLPK
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Disorder 







??




























?



















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   .........310.........320.........330.........340.........350.........360
Sequence  GPYGTVLSNPPYGERLDSEPALIALHSLLGRIMKNQFGGWNLSLFSASPDLLSCLQLRAD
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   .........370.........380.........390.........400.........410.........420
Sequence  KQYKAKNGPLDCVQKNYHVAESTPDSKPAMVAEDYTNRLRKNLKKFEKWARQEGIECYRL
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Disorder 


















??????????????


























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   .........430.........440.........450.........460.........470.........480
Sequence  YDADLPEYNVAVDRYADWVVVQEYAPPKTIDAHKARQRLFDIIAATISVLGIAPNKLVLK
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?
?



















?







??
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   .........490.........500.........510.........520.........530.........540
Sequence  TRERQKGKNQYQKLGEKGEFLEVTEYNAHLWVNLTDYLDTGLFLDHRIARRMLGQMSKGK
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Disorder  ???????????
















































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   .........550.........560.........570.........580.........590.........600
Sequence  DFLNLFSYTGSATVHAGLGGARSTTTVDMSRTYLEWAERNLRLNGLTGRAHRLIQADCLA
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   .........610.........620.........630.........640.........650.........660
Sequence  WLREANEQFDLIFIDPPTFSNSKRMEDAFDVQRDHLALMKDLKRLLRAGGTIMFSNNKRG
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   .........670.........680.........690.........700..
Sequence  FRMDLDGLAKLGLKAQEITQKTLSQDFARNRQIHNCWLITAA
Secondary structure 




















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Disorder 

















???

?????











??
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3ldu chain A

3D model

Region: 2 - 385
Aligned: 374
Modelled: 381
Confidence: 100.0%
Identity: 33%
PDB header:transferase
Chain: A: PDB Molecule:putative methylase;
PDBTitle: the crystal structure of a possible methylase from2 clostridium difficile 630.

Phyre2

PDB 3k0b chain A

3D model

Region: 3 - 377
Aligned: 362
Modelled: 375
Confidence: 100.0%
Identity: 33%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:predicted n6-adenine-specific dna methylase;
PDBTitle: crystal structure of a predicted n6-adenine-specific dna methylase2 from listeria monocytogenes str. 4b f2365

Phyre2

PDB 3ldg chain A

3D model

Region: 2 - 377
Aligned: 364
Modelled: 376
Confidence: 100.0%
Identity: 33%
PDB header:transferase
Chain: A: PDB Molecule:putative uncharacterized protein smu.472;
PDBTitle: crystal structure of smu.472, a putative methyltransferase complexed2 with sah

Phyre2

PDB 2b78 chain A

3D model

Region: 387 - 700
Aligned: 292
Modelled: 314
Confidence: 100.0%
Identity: 29%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein smu.776;
PDBTitle: a putative sam-dependent methyltransferase from2 streptococcus mutans

Phyre2

PDB 2b78 chain A domain 2

3D model

Region: 390 - 700
Aligned: 289
Modelled: 311
Confidence: 100.0%
Identity: 30%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: hypothetical RNA methyltransferase

Phyre2

PDB 3c0k chain B

3D model

Region: 385 - 692
Aligned: 295
Modelled: 308
Confidence: 100.0%
Identity: 26%
PDB header:transferase
Chain: B: PDB Molecule:upf0064 protein yccw;
PDBTitle: crystal structure of a ribosomal rna methyltranferase

Phyre2

PDB 1wxx chain A domain 2

3D model

Region: 395 - 694
Aligned: 285
Modelled: 300
Confidence: 100.0%
Identity: 31%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: hypothetical RNA methyltransferase

Phyre2

PDB 2as0 chain A

3D model

Region: 383 - 691
Aligned: 293
Modelled: 308
Confidence: 100.0%
Identity: 24%
PDB header:transferase
Chain: A: PDB Molecule:hypothetical protein ph1915;
PDBTitle: crystal structure of ph1915 (apc 5817): a hypothetical rna2 methyltransferase

Phyre2

PDB 2as0 chain A domain 2

3D model

Region: 390 - 692
Aligned: 287
Modelled: 301
Confidence: 100.0%
Identity: 25%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: hypothetical RNA methyltransferase

Phyre2

PDB 1wxw chain A

3D model

Region: 386 - 691
Aligned: 286
Modelled: 306
Confidence: 100.0%
Identity: 30%
PDB header:transferase
Chain: A: PDB Molecule:hypothetical protein ttha1280;
PDBTitle: crystal structure of tt1595, a putative sam-dependent2 methyltransferase from thermus thermophillus hb8

Phyre2

PDB 2igt chain A domain 1

3D model

Region: 413 - 659
Aligned: 226
Modelled: 231
Confidence: 100.0%
Identity: 22%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: hypothetical RNA methyltransferase

Phyre2

PDB 1o9g chain A

3D model

Region: 153 - 377
Aligned: 210
Modelled: 224
Confidence: 100.0%
Identity: 20%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: rRNA methyltransferase AviRa

Phyre2

PDB 2yx1 chain A

3D model

Region: 433 - 700
Aligned: 227
Modelled: 249
Confidence: 100.0%
Identity: 17%
PDB header:transferase
Chain: A: PDB Molecule:hypothetical protein mj0883;
PDBTitle: crystal structure of m.jannaschii trna m1g37 methyltransferase

Phyre2

PDB 2frn chain A domain 1

3D model

Region: 433 - 700
Aligned: 224
Modelled: 253
Confidence: 99.9%
Identity: 13%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: Met-10+ protein-like

Phyre2

PDB 3a26 chain A

3D model

Region: 433 - 702
Aligned: 231
Modelled: 252
Confidence: 99.9%
Identity: 13%
PDB header:transferase
Chain: A: PDB Molecule:uncharacterized protein ph0793;
PDBTitle: crystal structure of p. horikoshii tyw2 in complex with2 mesado

Phyre2

PDB 1nv8 chain A

3D model

Region: 459 - 698
Aligned: 229
Modelled: 240
Confidence: 99.8%
Identity: 16%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: N5-glutamine methyltransferase, HemK

Phyre2

PDB 3axt chain A

3D model

Region: 502 - 656
Aligned: 140
Modelled: 140
Confidence: 99.8%
Identity: 18%
PDB header:transferase
Chain: A: PDB Molecule:probable n(2),n(2)-dimethylguanosine trna methyltransferase
PDBTitle: complex structure of trna methyltransferase trm1 from aquifex aeolicus2 with s-adenosyl-l-methionine

Phyre2

PDB 3a27 chain A

3D model

Region: 489 - 670
Aligned: 160
Modelled: 167
Confidence: 99.8%
Identity: 14%
PDB header:transferase
Chain: A: PDB Molecule:uncharacterized protein mj1557;
PDBTitle: crystal structure of m. jannaschii tyw2 in complex with2 adomet

Phyre2

PDB 1uwv chain A domain 2

3D model

Region: 498 - 701
Aligned: 183
Modelled: 190
Confidence: 99.8%
Identity: 21%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: (Uracil-5-)-methyltransferase

Phyre2

PDB 2dul chain A domain 1

3D model

Region: 500 - 656
Aligned: 136
Modelled: 148
Confidence: 99.8%
Identity: 21%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: TRM1-like

Phyre2
1

c3lduA_
2

c3k0bA_
3

c3ldgA_
4

c2b78A_
5

d2b78a2
6

c3c0kB_
7

d1wxxa2
8

c2as0A_
9

d2as0a2
10

c1wxwA_
11

d2igta1
12

d1o9ga_
13

c2yx1A_
14

d2frna1
15

c3a26A_
16

d1nv8a_
17

c3axtA_
18

c3a27A_
19

d1uwva2
20

d2dula1
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3lduA_



100.0 33 PDB header:transferase
Chain: A: PDB Molecule:putative methylase;
PDBTitle: the crystal structure of a possible methylase from2 clostridium difficile 630.
2c3k0bA_



100.0 33 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:predicted n6-adenine-specific dna methylase;
PDBTitle: crystal structure of a predicted n6-adenine-specific dna methylase2 from listeria monocytogenes str. 4b f2365
3c3ldgA_



100.0 33 PDB header:transferase
Chain: A: PDB Molecule:putative uncharacterized protein smu.472;
PDBTitle: crystal structure of smu.472, a putative methyltransferase complexed2 with sah
4c2b78A_



100.0 29 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein smu.776;
PDBTitle: a putative sam-dependent methyltransferase from2 streptococcus mutans
5d2b78a2



100.0 30 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:hypothetical RNA methyltransferase
6c3c0kB_



100.0 26 PDB header:transferase
Chain: B: PDB Molecule:upf0064 protein yccw;
PDBTitle: crystal structure of a ribosomal rna methyltranferase
7d1wxxa2



100.0 31 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:hypothetical RNA methyltransferase
8c2as0A_



100.0 24 PDB header:transferase
Chain: A: PDB Molecule:hypothetical protein ph1915;
PDBTitle: crystal structure of ph1915 (apc 5817): a hypothetical rna2 methyltransferase
9d2as0a2



100.0 25 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:hypothetical RNA methyltransferase
10c1wxwA_



100.0 30 PDB header:transferase
Chain: A: PDB Molecule:hypothetical protein ttha1280;
PDBTitle: crystal structure of tt1595, a putative sam-dependent2 methyltransferase from thermus thermophillus hb8
11d2igta1



100.0 22 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:hypothetical RNA methyltransferase
12d1o9ga_



100.0 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:rRNA methyltransferase AviRa
13c2yx1A_



100.0 17 PDB header:transferase
Chain: A: PDB Molecule:hypothetical protein mj0883;
PDBTitle: crystal structure of m.jannaschii trna m1g37 methyltransferase
14d2frna1



99.9 13 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Met-10+ protein-like
15c3a26A_



99.9 13 PDB header:transferase
Chain: A: PDB Molecule:uncharacterized protein ph0793;
PDBTitle: crystal structure of p. horikoshii tyw2 in complex with2 mesado
16d1nv8a_



99.8 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:N5-glutamine methyltransferase, HemK
17c3axtA_



99.8 18 PDB header:transferase
Chain: A: PDB Molecule:probable n(2),n(2)-dimethylguanosine trna methyltransferase
PDBTitle: complex structure of trna methyltransferase trm1 from aquifex aeolicus2 with s-adenosyl-l-methionine
18c3a27A_



99.8 14 PDB header:transferase
Chain: A: PDB Molecule:uncharacterized protein mj1557;
PDBTitle: crystal structure of m. jannaschii tyw2 in complex with2 adomet
19d1uwva2



99.8 21 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:(Uracil-5-)-methyltransferase
20d2dula1



99.8 21 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:TRM1-like
21c3bt7A_



not modelled 99.8 15 PDB header:transferase/rna
Chain: A: PDB Molecule:trna (uracil-5-)-methyltransferase;
PDBTitle: structure of e. coli 5-methyluridine methyltransferase trma2 in complex with 19 nucleotide t-arm analogue
22c1uwvA_



not modelled 99.8 22 PDB header:transferase
Chain: A: PDB Molecule:23s rrna (uracil-5-)-methyltransferase ruma;
PDBTitle: crystal structure of ruma, the iron-sulfur cluster2 containing e. coli 23s ribosomal rna 5-methyluridine3 methyltransferase
23d2ifta1



not modelled 99.8 21 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:YhhF-like
24d2fhpa1



not modelled 99.8 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:YhhF-like
25d2fpoa1



not modelled 99.8 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:YhhF-like
26c2vs1A_



not modelled 99.8 23 PDB header:transferase
Chain: A: PDB Molecule:uncharacterized rna methyltransferase pyrab10780;
PDBTitle: the crystal structure of pyrococcus abyssi trna (uracil-54,2 c5)-methyltransferase in complex with s-adenosyl-l-3 homocysteine
27c3a4tA_



not modelled 99.7 18 PDB header:transferase
Chain: A: PDB Molecule:putative methyltransferase mj0026;
PDBTitle: crystal structure of atrm4 from m.jannaschii with sinefungin
28c3p9nA_



not modelled 99.7 21 PDB header:transferase
Chain: A: PDB Molecule:possible methyltransferase (methylase);
PDBTitle: rv2966c of m. tuberculosis is a rsmd-like methyltransferase
29d2b3ta1



not modelled 99.7 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:N5-glutamine methyltransferase, HemK
30d2esra1



not modelled 99.7 21 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:YhhF-like
31c2esrB_



not modelled 99.7 22 PDB header:transferase
Chain: B: PDB Molecule:methyltransferase;
PDBTitle: conserved hypothetical protein- streptococcus pyogenes
32d1wy7a1



not modelled 99.7 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Ta1320-like
33c3dmgA_



not modelled 99.7 18 PDB header:transferase
Chain: A: PDB Molecule:probable ribosomal rna small subunit methyltransferase;
PDBTitle: t. thermophilus 16s rrna n2 g1207 methyltransferase (rsmc) in complex2 with adohcy
34d1sqga2



not modelled 99.7 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:NOL1/NOP2/sun
35c3c6kC_



not modelled 99.6 18 PDB header:transferase
Chain: C: PDB Molecule:spermine synthase;
PDBTitle: crystal structure of human spermine synthase in complex2 with spermidine and 5-methylthioadenosine
36d1ws6a1



not modelled 99.6 25 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:YhhF-like
37c3evzA_



not modelled 99.6 16 PDB header:transferase
Chain: A: PDB Molecule:methyltransferase;
PDBTitle: crystal strucure of methyltransferase from pyrococcus furiosus
38c3egiA_



not modelled 99.6 19 PDB header:transferase
Chain: A: PDB Molecule:trimethylguanosine synthase homolog;
PDBTitle: methyltransferase domain of human trimethylguanosine2 synthase tgs1 bound to m7gpppa (inactive form)
39c3lpmA_



not modelled 99.6 16 PDB header:transferase
Chain: A: PDB Molecule:putative methyltransferase;
PDBTitle: crystal structure of putative methyltransferase small domain protein2 from listeria monocytogenes
40d2nxca1



not modelled 99.6 22 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Ribosomal protein L11 methyltransferase PrmA
41c3grzA_



not modelled 99.6 23 PDB header:transferase
Chain: A: PDB Molecule:ribosomal protein l11 methyltransferase;
PDBTitle: crystal structure of ribosomal protein l11 methylase from2 lactobacillus delbrueckii subsp. bulgaricus
42d1dusa_



not modelled 99.5 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Hypothetical protein MJ0882
43c3gdhC_



not modelled 99.5 21 PDB header:transferase
Chain: C: PDB Molecule:trimethylguanosine synthase homolog;
PDBTitle: methyltransferase domain of human trimethylguanosine2 synthase 1 (tgs1) bound to m7gtp and adenosyl-homocysteine3 (active form)
44c2r6zA_



not modelled 99.5 12 PDB header:transferase
Chain: A: PDB Molecule:upf0341 protein in rsp 3' region;
PDBTitle: crystal structure of the sam-dependent methyltransferase2 ngo1261 from neisseria gonorrhoeae, northeast structural3 genomics consortium target ngr48
45c2yxlA_



not modelled 99.5 13 PDB header:transferase
Chain: A: PDB Molecule:450aa long hypothetical fmu protein;
PDBTitle: crystal structure of ph0851
46c3khkA_



not modelled 99.5 16 PDB header:dna binding protein
Chain: A: PDB Molecule:type i restriction-modification system
PDBTitle: crystal structure of type-i restriction-modification system2 methylation subunit (mm_0429) from methanosarchina mazei.
47d2ar0a1



not modelled 99.5 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:N-6 DNA Methylase-like
48d1ixka_



not modelled 99.5 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:NOL1/NOP2/sun
49d2okca1



not modelled 99.5 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:N-6 DNA Methylase-like
50c3lkdB_



not modelled 99.5 20 PDB header:transferase
Chain: B: PDB Molecule:type i restriction-modification system
PDBTitle: crystal structure of the type i restriction-modification2 system methyltransferase subunit from streptococcus3 thermophilus, northeast structural genomics consortium4 target sur80
51c2ozvA_



not modelled 99.5 17 PDB header:transferase
Chain: A: PDB Molecule:hypothetical protein atu0636;
PDBTitle: crystal structure of a predicted o-methyltransferase, protein atu6362 from agrobacterium tumefaciens.
52c2pjdA_



not modelled 99.5 20 PDB header:transferase
Chain: A: PDB Molecule:ribosomal rna small subunit methyltransferase c;
PDBTitle: crystal structure of 16s rrna methyltransferase rsmc
53d1l3ia_



not modelled 99.4 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Precorrin-6Y methyltransferase (CbiT)
54c3q87B_



not modelled 99.4 17 PDB header:transferase activator/transferase
Chain: B: PDB Molecule:n6 adenine specific dna methylase;
PDBTitle: structure of eukaryotic translation termination complex2 methyltransferase mtq2-trm112
55c1sqgA_



not modelled 99.4 18 PDB header:transferase
Chain: A: PDB Molecule:sun protein;
PDBTitle: the crystal structure of the e. coli fmu apoenzyme at 1.652 a resolution
56c3e05B_



not modelled 99.4 14 PDB header:transferase
Chain: B: PDB Molecule:precorrin-6y c5,15-methyltransferase (decarboxylating);
PDBTitle: crystal structure of precorrin-6y c5,15-methyltransferase from2 geobacter metallireducens gs-15
57c1aqjB_



not modelled 99.4 26 PDB header:methyltransferase
Chain: B: PDB Molecule:adenine-n6-dna-methyltransferase taqi;
PDBTitle: structure of adenine-n6-dna-methyltransferase taqi
58c3eeyJ_



not modelled 99.4 11 PDB header:transferase
Chain: J: PDB Molecule:putative rrna methylase;
PDBTitle: crystal structure of putative rrna-methylase from clostridium2 thermocellum
59c3m6wA_



not modelled 99.4 15 PDB header:transferase
Chain: A: PDB Molecule:rrna methylase;
PDBTitle: multi-site-specific 16s rrna methyltransferase rsmf from thermus2 thermophilus in space group p21212 in complex with s-adenosyl-l-3 methionine
60d2f8la1



not modelled 99.4 23 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:N-6 DNA Methylase-like
61c3mtiA_



not modelled 99.4 13 PDB header:transferase
Chain: A: PDB Molecule:rrna methylase;
PDBTitle: the crystal structure of a rrna methylase from streptococcus2 thermophilus to 1.95a
62c1g38A_



not modelled 99.4 27 PDB header:transferase/dna
Chain: A: PDB Molecule:modification methylase taqi;
PDBTitle: adenine-specific methyltransferase m. taq i/dna complex
63c3bzbA_



not modelled 99.4 19 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of uncharacterized protein cmq451c from the2 primitive red alga cyanidioschyzon merolae
64c2gpyB_



not modelled 99.4 19 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:o-methyltransferase;
PDBTitle: crystal structure of putative o-methyltransferase from bacillus2 halodurans
65c3ku1E_



not modelled 99.4 18 PDB header:transferase
Chain: E: PDB Molecule:sam-dependent methyltransferase;
PDBTitle: crystal structure of streptococcus pneumoniae sp1610, a2 putative trna (m1a22) methyltransferase, in complex with s-3 adenosyl-l-methionine
66d1o54a_



not modelled 99.3 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:tRNA(1-methyladenosine) methyltransferase-like
67c3hm2G_



not modelled 99.3 12 PDB header:transferase
Chain: G: PDB Molecule:precorrin-6y c5,15-methyltransferase;
PDBTitle: crystal structure of putative precorrin-6y c5,15-2 methyltransferase targeted domain from corynebacterium3 diphtheriae
68c3cbgA_



not modelled 99.3 24 PDB header:transferase
Chain: A: PDB Molecule:o-methyltransferase;
PDBTitle: functional and structural characterization of a2 cationdependent o-methyltransferase from the3 cyanobacterium synechocystis sp. strain pcc 6803
69d2b9ea1



not modelled 99.3 15 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:NOL1/NOP2/sun
70d1susa1



not modelled 99.3 23 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:COMT-like
71c2yxdA_



not modelled 99.3 14 PDB header:transferase
Chain: A: PDB Molecule:probable cobalt-precorrin-6y c(15)-methyltransferase
PDBTitle: crystal structure of cobalamin biosynthesis precorrin 8w decarboxylase2 (cbit)
72d2fcaa1



not modelled 99.3 13 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:TrmB-like
73d1oria_



not modelled 99.3 21 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Arginine methyltransferase
74c3c3yB_



not modelled 99.3 21 PDB header:transferase
Chain: B: PDB Molecule:o-methyltransferase;
PDBTitle: crystal structure of pfomt, phenylpropanoid and flavonoid o-2 methyltransferase from m. crystallinum
75d1yzha1



not modelled 99.3 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:TrmB-like
76c3duwB_



not modelled 99.3 27 PDB header:transferase
Chain: B: PDB Molecule:o-methyltransferase, putative;
PDBTitle: crystal structural analysis of the o-methyltransferase from2 bacillus cereus in complex sah
77c2frxD_



not modelled 99.3 15 PDB header:transferase
Chain: D: PDB Molecule:hypothetical protein yebu;
PDBTitle: crystal structure of yebu, a m5c rna methyltransferase from e.coli
78c3njrB_



not modelled 99.3 21 PDB header:transferase
Chain: B: PDB Molecule:precorrin-6y methylase;
PDBTitle: crystal structure of c-terminal domain of precorrin-6y c5,15-2 methyltransferase from rhodobacter capsulatus
79c2hnkC_



not modelled 99.3 22 PDB header:transferase
Chain: C: PDB Molecule:sam-dependent o-methyltransferase;
PDBTitle: crystal structure of sam-dependent o-methyltransferase from2 pathogenic bacterium leptospira interrogans
80c3m4xA_



not modelled 99.3 14 PDB header:transferase
Chain: A: PDB Molecule:nol1/nop2/sun family protein;
PDBTitle: structure of a ribosomal methyltransferase
81d1zx0a1



not modelled 99.3 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Guanidinoacetate methyltransferase
82c3gnlB_



not modelled 99.3 14 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein, duf633, lmof2365_1472;
PDBTitle: structure of uncharacterized protein (lmof2365_1472) from2 listeria monocytogenes serotype 4b
83c3lecA_



not modelled 99.2 19 PDB header:structure genomics, unknown function
Chain: A: PDB Molecule:nadb-rossmann superfamily protein;
PDBTitle: the crystal structure of a protein in the nadb-rossmann2 superfamily from streptococcus agalactiae to 1.8a
84c3tfwB_



not modelled 99.2 24 PDB header:transferase
Chain: B: PDB Molecule:putative o-methyltransferase;
PDBTitle: crystal structure of a putative o-methyltransferase from klebsiella2 pneumoniae
85d2avda1



not modelled 99.2 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:COMT-like
86c3tr6A_



not modelled 99.2 26 PDB header:transferase
Chain: A: PDB Molecule:o-methyltransferase;
PDBTitle: structure of a o-methyltransferase from coxiella burnetii
87d1g6q1_



not modelled 99.2 22 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Arginine methyltransferase
88d2h00a1



not modelled 99.2 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Methyltransferase 10 domain
89c1orhA_



not modelled 99.2 20 PDB header:transferase
Chain: A: PDB Molecule:protein arginine n-methyltransferase 1;
PDBTitle: structure of the predominant protein arginine methyltransferase prmt1
90d1iy9a_



not modelled 99.2 15 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Spermidine synthase
91c2yvlB_



not modelled 99.2 16 PDB header:transferase
Chain: B: PDB Molecule:hypothetical protein;
PDBTitle: crystal structure of trna (m1a58) methyltransferase trmi from aquifex2 aeolicus
92d2fyta1



not modelled 99.2 22 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Arginine methyltransferase
93d2ex4a1



not modelled 99.2 22 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:AD-003 protein-like
94d1ri5a_



not modelled 99.2 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:mRNA cap (Guanine N-7) methyltransferase
95c2hteB_



not modelled 99.2 14 PDB header:transferase
Chain: B: PDB Molecule:spermidine synthase;
PDBTitle: the crystal structure of spermidine synthase from p. falciparum in2 complex with 5'-methylthioadenosine
96d1p1ca_



not modelled 99.2 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Guanidinoacetate methyltransferase
97d1kpia_



not modelled 99.2 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Mycolic acid cyclopropane synthase
98c1z3cA_



not modelled 99.2 16 PDB header:transferase
Chain: A: PDB Molecule:mrna capping enzyme;
PDBTitle: encephalitozooan cuniculi mrna cap (guanine-n7)2 methyltransferasein complexed with azoadomet
99c3dxyA_



not modelled 99.2 14 PDB header:transferase
Chain: A: PDB Molecule:trna (guanine-n(7)-)-methyltransferase;
PDBTitle: crystal structure of ectrmb in complex with sam
100c3mb5A_



not modelled 99.2 20 PDB header:transferase
Chain: A: PDB Molecule:sam-dependent methyltransferase;
PDBTitle: crystal structure of p. abyssi trna m1a58 methyltransferase in complex2 with s-adenosyl-l-methionine
101d1ne2a_



not modelled 99.2 23 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Ta1320-like
102c3opnA_



not modelled 99.1 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative hemolysin;
PDBTitle: the crystal structure of a putative hemolysin from lactococcus lactis
103d1inla_



not modelled 99.1 15 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Spermidine synthase
104c3ll7A_



not modelled 99.1 17 PDB header:transferase
Chain: A: PDB Molecule:putative methyltransferase;
PDBTitle: crystal structure of putative methyltransferase pg_1098 from2 porphyromonas gingivalis w83
105d1zq9a1



not modelled 99.1 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:rRNA adenine dimethylase-like
106c3m70A_



not modelled 99.1 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:tellurite resistance protein tehb homolog;
PDBTitle: crystal structure of tehb from haemophilus influenzae
107c1yb2A_



not modelled 99.1 19 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein ta0852;
PDBTitle: structure of a putative methyltransferase from thermoplasma2 acidophilum.
108d1yb2a1



not modelled 99.1 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:tRNA(1-methyladenosine) methyltransferase-like
109d1xvaa_



not modelled 99.1 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Glycine N-methyltransferase
110c3bgdB_



not modelled 99.1 13 PDB header:transferase
Chain: B: PDB Molecule:thiopurine s-methyltransferase;
PDBTitle: thiopurine s-methyltransferase
111d1l1ea_



not modelled 99.1 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Mycolic acid cyclopropane synthase
112c3dr5A_



not modelled 99.1 21 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative o-methyltransferase;
PDBTitle: crystal structure of the q8nrd3_corgl protein from2 corynebacterium glutamicum. northeast structural genomics3 consortium target cgr117.
113c3s1sA_



not modelled 99.1 24 PDB header:hydrolase, transferase
Chain: A: PDB Molecule:restriction endonuclease bpusi;
PDBTitle: characterization and crystal structure of the type iig restriction2 endonuclease bpusi
114d1tpya_



not modelled 99.1 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Mycolic acid cyclopropane synthase
115c3ntvB_



not modelled 99.1 21 PDB header:transferase
Chain: B: PDB Molecule:mw1564 protein;
PDBTitle: crystal structure of a putative caffeoyl-coa o-methyltransferase from2 staphylococcus aureus
116c3lccA_



not modelled 99.1 18 PDB header:transferase
Chain: A: PDB Molecule:putative methyl chloride transferase;
PDBTitle: structure of a sam-dependent halide methyltransferase from arabidopsis2 thaliana
117c3r3hA_



not modelled 99.1 26 PDB header:transferase
Chain: A: PDB Molecule:o-methyltransferase, sam-dependent;
PDBTitle: crystal structure of o-methyltransferase from legionella pneumophila
118d2b2ca1



not modelled 99.1 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Spermidine synthase
119c3b3jA_



not modelled 99.1 24 PDB header:transferase
Chain: A: PDB Molecule:histone-arginine methyltransferase carm1;
PDBTitle: the 2.55 a crystal structure of the apo catalytic domain of2 coactivator-associated arginine methyl transferase i(carm1:28-507,3 residues 28-146 and 479-507 not ordered)
120d1r74a_



not modelled 99.1 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Glycine N-methyltransferase

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0