Email l.a.kelley@imperial.ac.uk Description P33013 Date Thu Jan 5 11:50:49 GMT 2012 Unique Job ID 012be852a77f38a3

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1z6fA_ 100.0 49 PDB header:hydrolase Chain: A: PDB Molecule:penicillin-binding protein 5; PDBTitle: crystal structure of penicillin-binding protein 5 from e. coli in2 complex with a boronic acid inhibitor 2 c3it9B_ 100.0 50 PDB header:hydrolase Chain: B: PDB Molecule:d-alanyl-d-alanine carboxypeptidase dacc; PDBTitle: crystal structure of penicillin-binding protein 6 (pbp6)2 from e. coli in apo state 3 c3a3jA_ 100.0 50 PDB header:hydrolase Chain: A: PDB Molecule:pbp5; PDBTitle: crystal structures of penicillin binding protein 5 from2 haemophilus influenzae 4 c1xp4C_ 100.0 24 PDB header:hydrolase Chain: C: PDB Molecule:d-alanyl-d-alanine carboxypeptidase; PDBTitle: crystal structure of a peptidoglycan synthesis regulatory2 factor (pbp3) from streptococcus pneumoniae 5 c3mfdB_ 100.0 30 PDB header:hydrolase Chain: B: PDB Molecule:d-alanyl-d-alanine carboxypeptidase dacb; PDBTitle: the structure of the beta-lactamase superfamily domain of d-alanyl-d-2 alanine carboxypeptidase from bacillus subtilis 6 c1tvfA_ 100.0 25 PDB header:penicillin binding Chain: A: PDB Molecule:penicillin binding protein 4; PDBTitle: crystal structure of penicillin-binding protein 4 (pbp4)2 from staphylococcus aureus 7 c3humB_ 100.0 24 PDB header:hydrolase/antibiotics Chain: B: PDB Molecule:penicillin-binding protein 4; PDBTitle: crystal structure of penicillin binding protein 4 from2 staphylococcus aureus col in complex with cefotaxime 8 d1tvfa2 100.0 28 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 9 d3beca2 100.0 55 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 10 d1xp4a2 100.0 29 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 11 c2bcfA_ 100.0 29 PDB header:hydrolase Chain: A: PDB Molecule:probable d-alanyl-d-alanine carboxypeptidase PDBTitle: crystal structure of a evolved putative penicillin-binding2 protein homolog, rv2911, from mycobacterium tuberculosis. 12 d1es5a_ 100.0 32 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 13 c2v20A_ 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase tem; PDBTitle: structure of a tem-1 beta-lactamase insertant2 allosterically regulated by kanamycin and anions. complex3 with sulfate. 14 d1n9ba_ 100.0 15 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 15 d1m40a_ 100.0 15 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 16 c2j7vA_ 100.0 19 PDB header:hydrolase Chain: A: PDB Molecule:tll2115 protein; PDBTitle: structure of pbp-a 17 c3qhyA_ 100.0 17 PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:beta-lactamase; PDBTitle: structural, thermodynamic and kinetic analysis of the picomolar2 binding affinity interaction of the beta-lactamase inhibitor protein-3 ii (blip-ii) with class a beta-lactamases 18 d1o7ea_ 100.0 19 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 19 c3cg5A_ 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of the covalent adduct formed between tb2 b-lactamase and clavulanate 20 d1dy6a_ 100.0 15 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 21 c3dw0B_ not modelled 100.0 16 PDB header:hydrolase Chain: B: PDB Molecule:class a carbapenemase kpc-2; PDBTitle: crystal structure of the class a carbapenemase kpc-2 at 1.62 angstrom resolution 22 d1hzoa_ not modelled 100.0 20 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 23 c3p09B_ not modelled 100.0 13 PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of beta-lactamase from francisella tularensis 24 d1i2sa_ not modelled 100.0 17 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 25 c1i2sA_ not modelled 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: beta-lactamase from bacillus licheniformis bs3 26 c3cjmA_ not modelled 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:putative beta-lactamase; PDBTitle: crystal structure of putative beta-lactamase (np_815223.1) from2 enterococcus faecalis v583 at 1.50 a resolution 27 d2cc1a1 not modelled 100.0 21 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 28 d1iysa_ not modelled 100.0 16 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 29 c2ov5A_ not modelled 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:carbapenemase; PDBTitle: crystal structure of the kpc-2 carbapenemase 30 d1bsga_ not modelled 100.0 13 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 31 d1buea_ not modelled 100.0 17 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 32 c2wuqA_ not modelled 100.0 16 PDB header:transcription Chain: A: PDB Molecule:beta-lactamase regulatory protein blab; PDBTitle: crystal structure of blab protein from streptomyces cacaoi 33 c2qpnA_ not modelled 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase ges-1; PDBTitle: ges-1 beta-lactamase 34 d1g6aa_ not modelled 100.0 12 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 35 c3lezA_ not modelled 100.0 14 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of a halotolerant bacterial beta-lactamase 36 c3p09A_ not modelled 100.0 12 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of beta-lactamase from francisella tularensis 37 c1w7fB_ not modelled 100.0 16 PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of the class a beta-lactamase bs32 inhibited with isocitrate 38 d1alqa_ not modelled 100.0 15 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 39 d1djaa_ not modelled 100.0 14 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 40 d1e25a_ not modelled 100.0 17 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 41 c2wuqB_ not modelled 100.0 17 PDB header:transcription Chain: B: PDB Molecule:beta-lactamase regulatory protein blab; PDBTitle: crystal structure of blab protein from streptomyces cacaoi 42 c2xftA_ not modelled 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:orf12; PDBTitle: structural and mechanistic studies on a cephalosporin esterase from2 the clavulanic acid biosynthesis pathway 43 c3a3eB_ not modelled 99.9 21 PDB header:hydrolase Chain: B: PDB Molecule:penicillin-binding protein 4; PDBTitle: crystal structure of penicillin binding protein 4 (dacb)2 from haemophilus influenzae, complexed with novel beta-3 lactam (cmv) 44 d1w79a1 not modelled 99.9 23 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:Dac-like 45 d1w5da1 not modelled 99.9 21 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:Dac-like 46 d2ex2a1 not modelled 99.8 22 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:Dac-like 47 d3beca1 not modelled 99.8 34 Fold:Penicillin-binding protein associated domain Superfamily:Penicillin-binding protein associated domain Family:PBP5 C-terminal domain-like 48 d1nrfa_ not modelled 99.6 17 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 49 d1xa1a_ not modelled 99.6 15 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 50 c2iwdA_ not modelled 99.5 12 PDB header:antibiotic resistance Chain: A: PDB Molecule:methicillin resistance mecr1 protein; PDBTitle: oxacilloyl-acylated mecr1 extracellular antibiotic-sensor2 domain. 51 c3i7jB_ not modelled 99.5 16 PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase mb2281c; PDBTitle: crystal structure of a beta-lactamase (mb2281c) from2 mycobacterium bovis, northeast structural genomics3 consortium target mbr246 52 c2jc7A_ not modelled 99.5 18 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase oxa-24; PDBTitle: the crystal structure of the carbapenemase oxa-24 reveals2 new insights into the mechanism of carbapenem-hydrolysis 53 c3hbrD_ not modelled 99.3 16 PDB header:hydrolase Chain: D: PDB Molecule:oxa-48; PDBTitle: crystal structure of oxa-48 beta-lactamase 54 d1k38a_ not modelled 99.3 14 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 55 d1k55a_ not modelled 99.2 13 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 56 c3if6C_ not modelled 99.2 19 PDB header:hydrolase Chain: C: PDB Molecule:oxa-46 oxacillinase; PDBTitle: crystal structure of oxa-46 beta-lactamase from p.2 aeruginosa 57 d1vqqa3 not modelled 99.2 17 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 58 d1xp4a1 not modelled 99.2 19 Fold:Penicillin-binding protein associated domain Superfamily:Penicillin-binding protein associated domain Family:PBP5 C-terminal domain-like 59 c3pbqA_ not modelled 99.1 23 PDB header:hydrolase/antibiotic Chain: A: PDB Molecule:penicillin-binding protein 3; PDBTitle: crystal structure of pbp3 complexed with imipenem 60 c2wadB_ not modelled 99.1 20 PDB header:peptide binding protein Chain: B: PDB Molecule:penicillin-binding protein 2b; PDBTitle: penicillin-binding protein 2b (pbp-2b) from streptococcus2 pneumoniae (strain 5204) 61 d1yqsa1 not modelled 99.1 18 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 62 c3oc2A_ not modelled 99.1 29 PDB header:penicillin-binding protein Chain: A: PDB Molecule:penicillin-binding protein 3; PDBTitle: crystal structure of penicillin-binding protein 3 from pseudomonas2 aeruginosa 63 d1ci9a_ not modelled 99.0 28 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 64 c3hleA_ not modelled 99.0 18 PDB header:transferase Chain: A: PDB Molecule:transesterase; PDBTitle: simvastatin synthase (lovd), from aspergillus terreus, s5 mutant, s76a2 mutant, complex with monacolin j acid 65 c3lo7A_ not modelled 99.0 22 PDB header:transferase Chain: A: PDB Molecule:penicillin-binding protein a; PDBTitle: crystal structure of pbpa from mycobacterium tuberculosis 66 c2qmiH_ not modelled 99.0 18 PDB header:hydrolase Chain: H: PDB Molecule:pbp related beta-lactamase; PDBTitle: structure of the octameric penicillin-binding protein2 homologue from pyrococcus abyssi 67 c2qz6A_ not modelled 99.0 20 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: first crystal structure of a psychrophile class c beta-2 lactamase 68 d1m6ka_ not modelled 99.0 15 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 69 c3equB_ not modelled 98.9 21 PDB header:biosynthetic protein Chain: B: PDB Molecule:penicillin-binding protein 2; PDBTitle: crystal structure of penicillin-binding protein 2 from neisseria2 gonorrhoeae 70 d2dcfa1 not modelled 98.9 27 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 71 d1rp5a4 not modelled 98.9 18 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 72 d1rgya_ not modelled 98.9 23 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 73 c3tg9A_ not modelled 98.9 15 PDB header:penicillin binding protein Chain: A: PDB Molecule:penicillin-binding protein; PDBTitle: the crystal structure of penicillin binding protein from bacillus2 halodurans 74 c3o3vB_ not modelled 98.9 19 PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of clbp peptidase domain 75 c2wzzA_ not modelled 98.8 20 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: amp-c beta-lactamase (pseudomonas aeruginosa)in complex2 with compound m-03 76 c3fwlA_ not modelled 98.8 17 PDB header:transferase, hydrolase Chain: A: PDB Molecule:penicillin-binding protein 1b; PDBTitle: crystal structure of the full-length transglycosylase pbp1b2 from escherichia coli 77 c1mwuA_ not modelled 98.8 16 PDB header:biosynthetic protein Chain: A: PDB Molecule:penicillin-binding protein 2a; PDBTitle: structure of methicillin acyl-penicillin binding protein 2a2 from methicillin resistant staphylococcus aureus strain3 27r at 2.60 a resolution. 78 d1ei5a3 not modelled 98.8 14 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 79 d2hdsa1 not modelled 98.8 19 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 80 d2drwa1 not modelled 98.8 16 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 81 c3ozhA_ not modelled 98.7 12 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase/d-alanine carboxypeptidase; PDBTitle: crystal structure of beta-lactamase/d-alanine carboxypeptidase from2 yersinia pestis 82 c1zkjA_ not modelled 98.7 18 PDB header:hydrolase Chain: A: PDB Molecule:extended-spectrum beta-lactamase; PDBTitle: structural basis for the extended substrate spectrum of cmy-2 10, a plasmid-encoded class c beta-lactamase 83 d1pyya4 not modelled 98.7 17 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 84 c1qmfA_ not modelled 98.7 21 PDB header:peptidoglycan synthesis Chain: A: PDB Molecule:penicillin-binding protein 2x; PDBTitle: penicillin-binding protein 2x (pbp-2x) acyl-enzyme complex 85 d1onha_ not modelled 98.7 18 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 86 c3udiA_ not modelled 98.6 17 PDB header:penicillin-binding protein/antibiotic Chain: A: PDB Molecule:penicillin-binding protein 1a; PDBTitle: crystal structure of acinetobacter baumannii pbp1a in complex with2 penicillin g 87 c1ei5A_ not modelled 98.6 13 PDB header:hydrolase Chain: A: PDB Molecule:d-aminopeptidase; PDBTitle: crystal structure of a d-aminopeptidase from ochrobactrum2 anthropi 88 c3ue3A_ not modelled 98.6 21 PDB header:transferase Chain: A: PDB Molecule:septum formation, penicillin binding protein 3, PDBTitle: crystal structure of acinetobacter baumanni pbp3 89 d2c5wb1 not modelled 98.5 14 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 90 c1pmdA_ not modelled 98.2 16 PDB header:peptidoglycan synthesis Chain: A: PDB Molecule:peptidoglycan synthesis multifunctional enzyme; PDBTitle: penicillin-binding protein 2x (pbp-2x) 91 c2olvA_ not modelled 98.1 21 PDB header:transferase Chain: A: PDB Molecule:penicillin-binding protein 2; PDBTitle: structural insight into the transglycosylation step of bacterial cell2 wall biosynthesis : donor ligand complex 92 c2bg1A_ not modelled 98.1 22 PDB header:peptidoglycan Chain: A: PDB Molecule:penicillin-binding protein 1b; PDBTitle: active site restructuring regulates ligand recognition in2 classa penicillin-binding proteins (pbps) 93 d2bg1a1 not modelled 98.1 20 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 94 c3dwkC_ not modelled 98.0 19 PDB header:transferase Chain: C: PDB Molecule:penicillin-binding protein 2; PDBTitle: identification of dynamic structural motifs involved in2 peptidoglycan glycosyltransfer 95 d2olua2 not modelled 98.0 18 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 96 c2jciA_ not modelled 97.9 23 PDB header:drug-binding protein Chain: A: PDB Molecule:penicillin-binding protein 1b; PDBTitle: structural insights into the catalytic mechanism and the2 role of streptococcus pneumoniae pbp1b 97 d1k25a4 not modelled 97.7 22 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 98 c2pbyB_ not modelled 70.5 13 PDB header:hydrolase Chain: B: PDB Molecule:glutaminase; PDBTitle: probable glutaminase from geobacillus kaustophilus hta426 99 d1u60a_ not modelled 68.1 18 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:Glutaminase 100 c3czdA_ not modelled 64.7 15 PDB header:hydrolase Chain: A: PDB Molecule:glutaminase kidney isoform; PDBTitle: crystal structure of human glutaminase in complex with l-glutamate 101 c2dfwA_ not modelled 59.9 18 PDB header:hydrolase Chain: A: PDB Molecule:salt-tolerant glutaminase; PDBTitle: crystal structure of a major fragment of the salt-tolerant2 glutaminase from micrococcus luteus k-3 102 c3ih9A_ not modelled 58.1 18 PDB header:hydrolase Chain: A: PDB Molecule:salt-tolerant glutaminase; PDBTitle: crystal structure analysis of mglu in its tris form 103 c3uo9B_ not modelled 54.6 15 PDB header:hydrolase/hydrolase inhibitor Chain: B: PDB Molecule:glutaminase kidney isoform, mitochondrial; PDBTitle: crystal structure of human gac in complex with glutamate and bptes 104 d1uwfa1 not modelled 51.1 14 Fold:Common fold of diphtheria toxin/transcription factors/cytochrome f Superfamily:Bacterial adhesins Family:Pilus subunits 105 c3l9vE_ not modelled 29.5 12 PDB header:oxidoreductase Chain: E: PDB Molecule:putative thiol-disulfide isomerase or thioredoxin; PDBTitle: crystal structure of salmonella enterica serovar typhimurium srga 106 c3nqyA_ not modelled 26.0 21 PDB header:hydrolase Chain: A: PDB Molecule:secreted metalloprotease mcp02; PDBTitle: crystal structure of the autoprocessed complex of vibriolysin mcp-022 with a single point mutation e346a