Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	E	T	A	K	K	V	I	V	G	M	S	G	G	V	D	S	S	V	S	A	W	L	L	Q	Q	Q	G	Y	Q	V	E	G	L	F	M	K	N	W	E	E	D	D	G	E	E	Y	C	T	A	A	A	D	L	A	D	A	Q	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																																				?		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	C	D	K	L	G	I	E	L	H	T	V	N	F	A	A	E	Y	W	D	N	V	F	E	L	F	L	A	E	Y	K	A	G	R	T	P	N	P	D	I	L	C	N	K	E	I	K	F	K	A	F	L	E	F	A	A	E	D	L	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	D	Y	I	A	T	G	H	Y	V	R	R	A	D	V	D	G	K	S	R	L	L	R	G	L	D	S	N	K	D	Q	S	Y	F	L	Y	T	L	S	H	E	Q	I	A	Q	S	L	F	P	V	G	E	L	E	K	P	Q	V	R	K
Secondary structure
SS confidence
Disorder											?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		I	A	E	D	L	G	L	V	T	A	K	K	K	D	S	T	G	I	C	F	I	G	E	R	K	F	R	E	F	L	G	R	Y	L	P	A	Q	P	G	K	I	I	T	V	D	G	D	E	I	G	E	H	Q	G	L	M	Y	H	T	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		G	Q	R	K	G	L	G	I	G	G	T	K	E	G	T	E	E	P	W	Y	V	V	D	K	D	V	E	N	N	I	L	V	V	A	Q	G	H	E	H	P	R	L	M	S	V	G	L	I	A	Q	Q	L	H	W	V	D	R	E	P	F
Secondary structure
SS confidence
Disorder										?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		T	G	T	M	R	C	T	V	K	T	R	Y	R	Q	T	D	I	P	C	T	V	K	A	L	D	D	D	R	I	E	V	I	F	D	E	P	V	A	A	V	T	P	G	Q	S	A	V	F	Y	N	G	E	V	C	L	G	G	G	I	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.
Sequence		E	Q	R	L	P	L	P	V
Secondary structure
SS confidence
Disorder				?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2hma chain A Region: 2 - 363 Aligned: 352 Modelled: 353 Confidence: 100.0% Identity: 60% PDB header:transferase Chain: A: PDB Molecule:probable trna (5-methylaminomethyl-2-thiouridylate)- PDBTitle: the crystal structure of trna (5-methylaminomethyl-2-thiouridylate)-2 methyltransferase trmu from streptococcus pneumoniae Phyre2 PDB 2der chain A Region: 5 - 368 Aligned: 348 Modelled: 348 Confidence: 100.0% Identity: 100% PDB header:transferase/rna Chain: A: PDB Molecule:trna-specific 2-thiouridylase mnma; PDBTitle: cocrystal structure of an rna sulfuration enzyme mnma and2 trna-glu in the initial trna binding state Phyre2 PDB 2vxo chain B Region: 4 - 193 Aligned: 180 Modelled: 182 Confidence: 100.0% Identity: 21% PDB header:ligase Chain: B: PDB Molecule:gmp synthase [glutamine-hydrolyzing]; PDBTitle: human gmp synthetase in complex with xmp Phyre2 PDB 3q4g chain A Region: 4 - 200 Aligned: 167 Modelled: 168 Confidence: 99.9% Identity: 25% PDB header:ligase Chain: A: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: structure of nad synthetase from vibrio cholerae Phyre2 PDB 2e21 chain A Region: 1 - 214 Aligned: 184 Modelled: 203 Confidence: 99.9% Identity: 17% PDB header:ligase Chain: A: PDB Molecule:trna(ile)-lysidine synthase; PDBTitle: crystal structure of tils in a complex with amppnp from aquifex2 aeolicus. Phyre2 PDB 2nz2 chain A Region: 5 - 195 Aligned: 170 Modelled: 191 Confidence: 99.9% Identity: 18% PDB header:ligase Chain: A: PDB Molecule:argininosuccinate synthase; PDBTitle: crystal structure of human argininosuccinate synthase in complex with2 aspartate and citrulline Phyre2 PDB 1wy5 chain A domain 1 Region: 1 - 214 Aligned: 184 Modelled: 207 Confidence: 99.9% Identity: 17% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: PP-loop ATPase Phyre2 PDB 3a2k chain B Region: 1 - 214 Aligned: 186 Modelled: 203 Confidence: 99.9% Identity: 17% PDB header:ligase/rna Chain: B: PDB Molecule:trna(ile)-lysidine synthase; PDBTitle: crystal structure of tils complexed with trna Phyre2 PDB 3k32 chain D Region: 8 - 235 Aligned: 188 Modelled: 202 Confidence: 99.9% Identity: 18% PDB header:transferase Chain: D: PDB Molecule:uncharacterized protein mj0690; PDBTitle: the crystal structure of predicted subunit of trna2 methyltransferase from methanocaldococcus jannaschii dsm Phyre2 PDB 3fiu chain D Region: 5 - 199 Aligned: 161 Modelled: 167 Confidence: 99.9% Identity: 24% PDB header:ligase Chain: D: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: structure of nmn synthetase from francisella tularensis Phyre2 PDB 2ywc chain C Region: 4 - 200 Aligned: 153 Modelled: 161 Confidence: 99.9% Identity: 26% PDB header:ligase Chain: C: PDB Molecule:gmp synthase [glutamine-hydrolyzing]; PDBTitle: crystal structure of gmp synthetase from thermus thermophilus in2 complex with xmp Phyre2 PDB 2c5s chain A Region: 4 - 187 Aligned: 153 Modelled: 170 Confidence: 99.9% Identity: 25% PDB header:rna-binding protein Chain: A: PDB Molecule:probable thiamine biosynthesis protein thii; PDBTitle: crystal structure of bacillus anthracis thii, a trna-2 modifying enzyme containing the predicted rna-binding3 thump domain Phyre2 PDB 1gpm chain A domain 1 Region: 4 - 193 Aligned: 151 Modelled: 166 Confidence: 99.9% Identity: 26% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: N-type ATP pyrophosphatases Phyre2 PDB 1vl2 chain C Region: 5 - 195 Aligned: 171 Modelled: 191 Confidence: 99.9% Identity: 20% PDB header:ligase Chain: C: PDB Molecule:argininosuccinate synthase; PDBTitle: crystal structure of argininosuccinate synthase (tm1780) from2 thermotoga maritima at 1.65 a resolution Phyre2 PDB 2c5s chain A domain 1 Region: 4 - 222 Aligned: 193 Modelled: 205 Confidence: 99.9% Identity: 20% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: ThiI-like Phyre2 PDB 1kqp chain A Region: 5 - 220 Aligned: 183 Modelled: 196 Confidence: 99.9% Identity: 19% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: N-type ATP pyrophosphatases Phyre2 PDB 1gpm chain D Region: 5 - 193 Aligned: 148 Modelled: 163 Confidence: 99.9% Identity: 28% PDB header:transferase (glutamine amidotransferase) Chain: D: PDB Molecule:gmp synthetase; PDBTitle: escherichia coli gmp synthetase complexed with amp and pyrophosphate Phyre2 PDB 3tqi chain B Region: 4 - 203 Aligned: 156 Modelled: 164 Confidence: 99.9% Identity: 28% PDB header:ligase Chain: B: PDB Molecule:gmp synthase [glutamine-hydrolyzing]; PDBTitle: structure of the gmp synthase (guaa) from coxiella burnetii Phyre2 PDB 2dpl chain A Region: 4 - 201 Aligned: 151 Modelled: 168 Confidence: 99.9% Identity: 28% PDB header:ligase Chain: A: PDB Molecule:gmp synthase [glutamine-hydrolyzing] subunit b; PDBTitle: crystal structure of the gmp synthase from pyrococcus horikoshii ot3 Phyre2 PDB 1wxi chain A domain 1 Region: 2 - 200 Aligned: 164 Modelled: 169 Confidence: 99.9% Identity: 21% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: N-type ATP pyrophosphatases Phyre2 1 c2hmaA_ 2 c2derA_ 3 c2vxoB_ 4 c3q4gA_ 5 c2e21A_ 6 c2nz2A_ 7 d1wy5a1 8 c3a2kB_ 9 c3k32D_ 10 c3fiuD_ 11 c2ywcC_ 12 c2c5sA_ 13 d1gpma1 14 c1vl2C_ 15 d2c5sa1 16 d1kqpa_ 17 c1gpmD_ 18 c3tqiB_ 19 c2dplA_ 20 d1wxia1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2hmaA_ 100.0 60 PDB header:transferase Chain: A: PDB Molecule:probable trna (5-methylaminomethyl-2-thiouridylate)- PDBTitle: the crystal structure of trna (5-methylaminomethyl-2-thiouridylate)-2 methyltransferase trmu from streptococcus pneumoniae 2 c2derA_ 100.0 100 PDB header:transferase/rna Chain: A: PDB Molecule:trna-specific 2-thiouridylase mnma; PDBTitle: cocrystal structure of an rna sulfuration enzyme mnma and2 trna-glu in the initial trna binding state 3 c2vxoB_ 100.0 21 PDB header:ligase Chain: B: PDB Molecule:gmp synthase [glutamine-hydrolyzing]; PDBTitle: human gmp synthetase in complex with xmp 4 c3q4gA_ 99.9 25 PDB header:ligase Chain: A: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: structure of nad synthetase from vibrio cholerae 5 c2e21A_ 99.9 17 PDB header:ligase Chain: A: PDB Molecule:trna(ile)-lysidine synthase; PDBTitle: crystal structure of tils in a complex with amppnp from aquifex2 aeolicus. 6 c2nz2A_ 99.9 18 PDB header:ligase Chain: A: PDB Molecule:argininosuccinate synthase; PDBTitle: crystal structure of human argininosuccinate synthase in complex with2 aspartate and citrulline 7 d1wy5a1 99.9 17 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:PP-loop ATPase 8 c3a2kB_ 99.9 17 PDB header:ligase/rna Chain: B: PDB Molecule:trna(ile)-lysidine synthase; PDBTitle: crystal structure of tils complexed with trna 9 c3k32D_ 99.9 18 PDB header:transferase Chain: D: PDB Molecule:uncharacterized protein mj0690; PDBTitle: the crystal structure of predicted subunit of trna2 methyltransferase from methanocaldococcus jannaschii dsm 10 c3fiuD_ 99.9 24 PDB header:ligase Chain: D: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: structure of nmn synthetase from francisella tularensis 11 c2ywcC_ 99.9 26 PDB header:ligase Chain: C: PDB Molecule:gmp synthase [glutamine-hydrolyzing]; PDBTitle: crystal structure of gmp synthetase from thermus thermophilus in2 complex with xmp 12 c2c5sA_ 99.9 25 PDB header:rna-binding protein Chain: A: PDB Molecule:probable thiamine biosynthesis protein thii; PDBTitle: crystal structure of bacillus anthracis thii, a trna-2 modifying enzyme containing the predicted rna-binding3 thump domain 13 d1gpma1 99.9 26 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 14 c1vl2C_ 99.9 20 PDB header:ligase Chain: C: PDB Molecule:argininosuccinate synthase; PDBTitle: crystal structure of argininosuccinate synthase (tm1780) from2 thermotoga maritima at 1.65 a resolution 15 d2c5sa1 99.9 20 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ThiI-like 16 d1kqpa_ 99.9 19 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 17 c1gpmD_ 99.9 28 PDB header:transferase (glutamine amidotransferase) Chain: D: PDB Molecule:gmp synthetase; PDBTitle: escherichia coli gmp synthetase complexed with amp and pyrophosphate 18 c3tqiB_ 99.9 28 PDB header:ligase Chain: B: PDB Molecule:gmp synthase [glutamine-hydrolyzing]; PDBTitle: structure of the gmp synthase (guaa) from coxiella burnetii 19 c2dplA_ 99.9 28 PDB header:ligase Chain: A: PDB Molecule:gmp synthase [glutamine-hydrolyzing] subunit b; PDBTitle: crystal structure of the gmp synthase from pyrococcus horikoshii ot3 20 d1wxia1 99.9 21 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 21 c1kh2D_ not modelled 99.9 15 PDB header:ligase Chain: D: PDB Molecule:argininosuccinate synthetase; PDBTitle: crystal structure of thermus thermophilus hb82 argininosuccinate synthetase in complex with atp 22 c3dpiA_ not modelled 99.9 24 PDB header:ligase Chain: A: PDB Molecule:nad+ synthetase; PDBTitle: crystal structure of nad+ synthetase from burkholderia pseudomallei 23 c1ni5A_ not modelled 99.9 17 PDB header:cell cycle Chain: A: PDB Molecule:putative cell cycle protein mesj; PDBTitle: structure of the mesj pp-atpase from escherichia coli 24 c2e18B_ not modelled 99.9 29 PDB header:ligase Chain: B: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: crystal structure of project ph0182 from pyrococcus horikoshii ot3 25 d1ni5a1 not modelled 99.9 17 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:PP-loop ATPase 26 c3p52B_ not modelled 99.9 22 PDB header:ligase Chain: B: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: nh3-dependent nad synthetase from campylobacter jejuni subsp. jejuni2 nctc 11168 in complex with the nitrate ion 27 d1vl2a1 not modelled 99.9 20 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 28 d1j20a1 not modelled 99.9 18 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 29 d1k92a1 not modelled 99.9 11 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 30 c3bl5E_ not modelled 99.8 23 PDB header:hydrolase Chain: E: PDB Molecule:queuosine biosynthesis protein quec; PDBTitle: crystal structure of quec from bacillus subtilis: an enzyme2 involved in preq1 biosynthesis 31 c3uowB_ not modelled 99.8 21 PDB header:ligase Chain: B: PDB Molecule:gmp synthetase; PDBTitle: crystal structure of pf10_0123, a gmp synthetase from plasmodium2 falciparum 32 d1xnga1 not modelled 99.8 26 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 33 c1k97A_ not modelled 99.8 14 PDB header:ligase Chain: A: PDB Molecule:argininosuccinate synthase; PDBTitle: crystal structure of e. coli argininosuccinate synthetase in complex2 with aspartate and citrulline 34 d2pg3a1 not modelled 99.8 19 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 35 d1vbka1 not modelled 99.8 16 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ThiI-like 36 c3n05B_ not modelled 99.7 23 PDB header:ligase Chain: B: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: crystal structure of nh3-dependent nad+ synthetase from streptomyces2 avermitilis 37 d1sura_ not modelled 99.6 13 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:PAPS reductase-like 38 d1ru8a_ not modelled 99.5 20 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 39 c2o8vA_ not modelled 99.4 13 PDB header:oxidoreductase Chain: A: PDB Molecule:phosphoadenosine phosphosulfate reductase; PDBTitle: paps reductase in a covalent complex with thioredoxin c35a 40 c1vbkA_ not modelled 99.4 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein ph1313; PDBTitle: crystal structure of ph1313 from pyrococcus horikoshii ot3 41 c3ilvA_ not modelled 99.4 15 PDB header:ligase Chain: A: PDB Molecule:glutamine-dependent nad(+) synthetase; PDBTitle: crystal structure of a glutamine-dependent nad(+) synthetase2 from cytophaga hutchinsonii 42 c3dlaD_ not modelled 99.3 16 PDB header:ligase Chain: D: PDB Molecule:glutamine-dependent nad(+) synthetase; PDBTitle: x-ray crystal structure of glutamine-dependent nad+ synthetase from2 mycobacterium tuberculosis bound to naad+ and don 43 c2goyC_ not modelled 99.3 13 PDB header:oxidoreductase Chain: C: PDB Molecule:adenosine phosphosulfate reductase; PDBTitle: crystal structure of assimilatory adenosine 5'-2 phosphosulfate reductase with bound aps 44 c1zunA_ not modelled 99.3 13 PDB header:transferase Chain: A: PDB Molecule:sulfate adenylyltransferase subunit 2; PDBTitle: crystal structure of a gtp-regulated atp sulfurylase2 heterodimer from pseudomonas syringae 45 d1zuna1 not modelled 99.3 13 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:PAPS reductase-like 46 c2oq2B_ not modelled 99.0 14 PDB header:oxidoreductase Chain: B: PDB Molecule:phosphoadenosine phosphosulfate reductase; PDBTitle: crystal structure of yeast paps reductase with pap, a product complex 47 c1ct9D_ not modelled 98.9 18 PDB header:ligase Chain: D: PDB Molecule:asparagine synthetase b; PDBTitle: crystal structure of asparagine synthetase b from2 escherichia coli 48 d1ct9a1 not modelled 98.9 17 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 49 d1q15a1 not modelled 98.8 18 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 50 d1jgta1 not modelled 98.7 20 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 51 c1q15A_ not modelled 98.6 18 PDB header:biosynthetic protein Chain: A: PDB Molecule:cara; PDBTitle: carbapenam synthetase 52 d2d13a1 not modelled 98.5 26 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 53 c3g59A_ not modelled 98.5 13 PDB header:transferase Chain: A: PDB Molecule:fmn adenylyltransferase; PDBTitle: crystal structure of candida glabrata fmn2 adenylyltransferase in complex with atp 54 c1m1zB_ not modelled 98.5 20 PDB header:hydrolase Chain: B: PDB Molecule:beta-lactam synthetase; PDBTitle: beta-lactam synthetase apo enzyme 55 c2wsiA_ not modelled 98.2 14 PDB header:transferase Chain: A: PDB Molecule:fad synthetase; PDBTitle: crystal structure of yeast fad synthetase (fad1) in complex2 with fad 56 c3o1lB_ not modelled 96.2 14 PDB header:hydrolase Chain: B: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (pspto_4314)2 from pseudomonas syringae pv. tomato str. dc3000 at 2.20 a resolution 57 c3n0vD_ not modelled 96.0 18 PDB header:hydrolase Chain: D: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (pp_0327)2 from pseudomonas putida kt2440 at 2.25 a resolution 58 c3louB_ not modelled 94.3 16 PDB header:hydrolase Chain: B: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of formyltetrahydrofolate deformylase (yp_105254.1)2 from burkholderia mallei atcc 23344 at 1.90 a resolution 59 c1m6vE_ not modelled 93.1 15 PDB header:ligase Chain: E: PDB Molecule:carbamoyl phosphate synthetase large chain; PDBTitle: crystal structure of the g359f (small subunit) point mutant of2 carbamoyl phosphate synthetase 60 c2ys6A_ not modelled 93.0 17 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylglycinamide synthetase; PDBTitle: crystal structure of gar synthetase from geobacillus kaustophilus 61 c1kk3A_ not modelled 92.4 22 PDB header:translation Chain: A: PDB Molecule:eif2gamma; PDBTitle: structure of the wild-type large gamma subunit of2 initiation factor eif2 from pyrococcus abyssi complexed3 with gdp-mg2+ 62 c1skqB_ not modelled 92.3 19 PDB header:translation Chain: B: PDB Molecule:elongation factor 1-alpha; PDBTitle: the crystal structure of sulfolobus solfataricus elongation2 factor 1-alpha in complex with magnesium and gdp 63 c3obiC_ not modelled 91.6 16 PDB header:hydrolase Chain: C: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (np_949368)2 from rhodopseudomonas palustris cga009 at 1.95 a resolution 64 c3e1yG_ not modelled 90.4 9 PDB header:translation Chain: G: PDB Molecule:eukaryotic peptide chain release factor gtp-binding subunit PDBTitle: crystal structure of human erf1/erf3 complex 65 d1d2ea2 not modelled 89.8 16 Fold:Elongation factor/aminomethyltransferase common domain Superfamily:EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain Family:EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 66 c2yyaB_ not modelled 86.4 16 PDB header:ligase Chain: B: PDB Molecule:phosphoribosylamine--glycine ligase; PDBTitle: crystal structure of gar synthetase from aquifex aeolicus 67 c2bvnB_ not modelled 86.3 21 PDB header:elongation factor Chain: B: PDB Molecule:elongation factor tu; PDBTitle: e. coli ef-tu:gdpnp in complex with the antibiotic2 enacyloxin iia 68 c3zquA_ not modelled 84.9 21 PDB header:lyase Chain: A: PDB Molecule:probable aromatic acid decarboxylase; PDBTitle: structure of a probable aromatic acid decarboxylase 69 c3nrbD_ not modelled 84.6 18 PDB header:hydrolase Chain: D: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (puru,2 pp_1943) from pseudomonas putida kt2440 at 2.05 a resolution 70 c3k5iB_ not modelled 84.0 17 PDB header:lyase Chain: B: PDB Molecule:phosphoribosyl-aminoimidazole carboxylase; PDBTitle: crystal structure of n5-carboxyaminoimidazole synthase from2 aspergillus clavatus in complex with adp and 5-3 aminoimadazole ribonucleotide 71 c3mcuF_ not modelled 82.7 21 PDB header:oxidoreductase Chain: F: PDB Molecule:dipicolinate synthase, b chain; PDBTitle: crystal structure of the dipicolinate synthase chain b from2 bacillus cereus. northeast structural genomics consortium3 target bcr215. 72 c2gn9B_ not modelled 81.8 8 PDB header:lyase Chain: B: PDB Molecule:udp-glcnac c6 dehydratase; PDBTitle: crystal structure of udp-glcnac inverting 4,6-dehydratase in complex2 with nadp and udp-glc 73 c3mmpC_ not modelled 81.7 17 PDB header:transferase Chain: C: PDB Molecule:elongation factor tu 2, elongation factor ts; PDBTitle: structure of the qb replicase, an rna-dependent rna polymerase2 consisting of viral and host proteins 74 c2xd4A_ not modelled 80.1 13 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylamine--glycine ligase; PDBTitle: nucleotide-bound structures of bacillus subtilis glycinamide2 ribonucleotide synthetase 75 c3lqkA_ not modelled 77.8 22 PDB header:oxidoreductase Chain: A: PDB Molecule:dipicolinate synthase subunit b; PDBTitle: crystal structure of dipicolinate synthase subunit b from bacillus2 halodurans c 76 c3fojA_ not modelled 77.6 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of ssp1007 from staphylococcus2 saprophyticus subsp. saprophyticus. northeast structural3 genomics target syr101a. 77 c3p9xB_ not modelled 77.2 15 PDB header:transferase Chain: B: PDB Molecule:phosphoribosylglycinamide formyltransferase; PDBTitle: crystal structure of phosphoribosylglycinamide formyltransferase from2 bacillus halodurans 78 c1wv9B_ not modelled 76.3 25 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:rhodanese homolog tt1651; PDBTitle: crystal structure of rhodanese homolog tt1651 from an2 extremely thermophilic bacterium thermus thermophilus hb8 79 c3agqA_ not modelled 75.0 15 PDB header:translation,transferase Chain: A: PDB Molecule:elongation factor ts, elongation factor tu 1, linker, q PDBTitle: structure of viral polymerase form ii 80 d1efca2 not modelled 73.7 21 Fold:Elongation factor/aminomethyltransferase common domain Superfamily:EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain Family:EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 81 c3enkB_ not modelled 73.3 18 PDB header:isomerase Chain: B: PDB Molecule:udp-glucose 4-epimerase; PDBTitle: 1.9a crystal structure of udp-glucose 4-epimerase from2 burkholderia pseudomallei 82 c2ejbA_ not modelled 73.3 19 PDB header:lyase Chain: A: PDB Molecule:probable aromatic acid decarboxylase; PDBTitle: crystal structure of phenylacrylic acid decarboxylase from2 aquifex aeolicus 83 c1s0uA_ not modelled 72.7 18 PDB header:translation Chain: A: PDB Molecule:translation initiation factor 2 gamma subunit; PDBTitle: eif2gamma apo 84 d1qzua_ not modelled 71.9 26 Fold:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Superfamily:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Family:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD 85 d1meoa_ not modelled 70.1 22 Fold:Formyltransferase Superfamily:Formyltransferase Family:Formyltransferase 86 d1qtwa_ not modelled 69.3 18 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Endonuclease IV 87 c2x7vA_ not modelled 68.4 18 PDB header:hydrolase Chain: A: PDB Molecule:probable endonuclease 4; PDBTitle: crystal structure of thermotoga maritima endonuclease iv in2 the presence of zinc 88 c3g5jA_ not modelled 67.8 24 PDB header:nucleotide binding protein Chain: A: PDB Molecule:putative atp/gtp binding protein; PDBTitle: crystal structure of n-terminal domain of putative atp/gtp binding2 protein from clostridium difficile 630 89 d1kk1a2 not modelled 65.5 36 Fold:Elongation factor/aminomethyltransferase common domain Superfamily:EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain Family:EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 90 d2c78a2 not modelled 65.4 25 Fold:Elongation factor/aminomethyltransferase common domain Superfamily:EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain Family:EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 91 c1mvlA_ not modelled 65.2 19 PDB header:lyase Chain: A: PDB Molecule:ppc decarboxylase athal3a; PDBTitle: ppc decarboxylase mutant c175s 92 d1mvla_ not modelled 65.2 19 Fold:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Superfamily:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Family:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD 93 d1p3y1_ not modelled 65.2 18 Fold:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Superfamily:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Family:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD 94 c2dzdB_ not modelled 64.9 17 PDB header:ligase Chain: B: PDB Molecule:pyruvate carboxylase; PDBTitle: crystal structure of the biotin carboxylase domain of2 pyruvate carboxylase 95 c3mcaA_ not modelled 63.9 12 PDB header:translation regulation/hydrolase Chain: A: PDB Molecule:elongation factor 1 alpha-like protein; PDBTitle: structure of the dom34-hbs1 complex and implications for its role in2 no-go decay 96 c2hdnJ_ not modelled 62.9 21 PDB header:translation Chain: J: PDB Molecule:elongation factor ef-tu; PDBTitle: trypsin-modified elongation factor tu in complex with2 tetracycline at 2.8 angstrom resolution 97 d1nbwa1 not modelled 61.7 28 Fold:The "swivelling" beta/beta/alpha domain Superfamily:Swiveling domain of dehydratase reactivase alpha subunit Family:Swiveling domain of dehydratase reactivase alpha subunit 98 c3e20A_ not modelled 60.6 16 PDB header:translation Chain: A: PDB Molecule:eukaryotic peptide chain release factor gtp-binding PDBTitle: crystal structure of s.pombe erf1/erf3 complex 99 c3ilmD_ not modelled 60.4 26 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:alr3790 protein; PDBTitle: crystal structure of the alr3790 protein from anabaena sp. northeast2 structural genomics consortium target nsr437h 100 d1yt8a4 not modelled 59.8 31 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 101 d1xgka_ not modelled 58.8 15 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 102 d1g5qa_ not modelled 58.1 19 Fold:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Superfamily:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Family:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD 103 d1qyca_ not modelled 57.8 14 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 104 d1sb8a_ not modelled 56.9 26 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 105 d1j8yf2 not modelled 56.4 16 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nitrogenase iron protein-like 106 c1qzuB_ not modelled 56.1 25 PDB header:lyase Chain: B: PDB Molecule:hypothetical protein mds018; PDBTitle: crystal structure of human phosphopantothenoylcysteine decarboxylase 107 c3qjgD_ not modelled 55.5 20 PDB header:oxidoreductase Chain: D: PDB Molecule:epidermin biosynthesis protein epid; PDBTitle: epidermin biosynthesis protein epid from staphylococcus aureus 108 d1jnya2 not modelled 54.8 15 Fold:Elongation factor/aminomethyltransferase common domain Superfamily:EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain Family:EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 109 c2jtqA_ not modelled 54.7 23 PDB header:transferase Chain: A: PDB Molecule:phage shock protein e; PDBTitle: rhodanese from e.coli 110 c3nbmA_ not modelled 51.7 16 PDB header:transferase Chain: A: PDB Molecule:pts system, lactose-specific iibc components; PDBTitle: the lactose-specific iib component domain structure of the2 phosphoenolpyruvate:carbohydrate phosphotransferase system (pts) from3 streptococcus pneumoniae. 111 d1gy8a_ not modelled 50.4 22 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 112 c2k0zA_ not modelled 50.0 24 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein hp1203; PDBTitle: solution nmr structure of protein hp1203 from helicobacter pylori2 26695. northeast structural genomics consortium (nesg) target3 pt1/ontario center for structural proteomics target hp1203 113 c2rh8A_ not modelled 49.1 20 PDB header:oxidoreductase Chain: A: PDB Molecule:anthocyanidin reductase; PDBTitle: structure of apo anthocyanidin reductase from vitis vinifera 114 c2kerA_ not modelled 48.7 23 PDB header:hydrolase inhibitor Chain: A: PDB Molecule:alpha-amylase inhibitor z-2685; PDBTitle: alpha-amylase inhibitor parvulustat (z-2685) from2 streptomyces parvulus 115 c1t2aC_ not modelled 48.3 29 PDB header:structural genomics,lyase Chain: C: PDB Molecule:gdp-mannose 4,6 dehydratase; PDBTitle: crystal structure of human gdp-d-mannose 4,6-dehydratase 116 d1t2aa_ not modelled 48.3 29 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 117 c3lp8A_ not modelled 48.2 14 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylamine-glycine ligase; PDBTitle: crystal structure of phosphoribosylamine-glycine ligase from2 ehrlichia chaffeensis 118 d1pjqa3 not modelled 48.2 47 Fold:Siroheme synthase middle domains-like Superfamily:Siroheme synthase middle domains-like Family:Siroheme synthase middle domains-like 119 d1rz3a_ not modelled 48.1 28 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Phosphoribulokinase/pantothenate kinase 120 c3opyE_ not modelled 47.3 25 PDB header:transferase Chain: E: PDB Molecule:6-phosphofructo-1-kinase alpha-subunit; PDBTitle: crystal structure of pichia pastoris phosphofructokinase in the t-2 state

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0