Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0ABB8
DateThu Jan 5 11:15:07 GMT 2012
Unique Job IDed422ca4087dac14

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2zxeA_
Top template information
PDB header:hydrolase/transport protein
Chain: A: PDB Molecule:na, k-atpase alpha subunit;
PDBTitle: crystal structure of the sodium - potassium pump in the e2.2k+.pi2 state
Confidence and coverage
Confidence:100.0% Coverage: 94%
846 residues ( 94% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MFKEIFTRLIRHLPSRLVHRDPLPGAQQTVNTVVPPSLSAHCLKMAVMPEEELWKTFDTH
Secondary structure 








































SS confidence 



























































Disorder  ??




?

????
??
??????????????????????

















??
Disorder confidence 



























































 
   .........70.........80.........90.........100.........110.........120
Sequence  PEGLNQAEVESAREQHGENKLPAQQPSPWWVHLWVCYRNPFNILLTILGAISYATEDLFA
Secondary structure 






















SS confidence 



























































Disorder  ?????










????



??

































Disorder confidence 



























































 
   .........130.........140.........150.........160.........170.........180
Sequence  AGVIALMVAISTLLNFIQEARSTKAADALKAMVSNTATVLRVINDKGENGWLEIPIDQLV
Secondary structure 












SS confidence 



























































Disorder 






























????
?






????











Disorder confidence 



























































 
   .........190.........200.........210.........220.........230.........240
Sequence  PGDIIKLAAGDMIPADLRILQARDLFVAQASLTGESLPVEKAATTRQPEHSNPLECDTLC
Secondary structure 







































SS confidence 



























































Disorder 








































??
??????









Disorder confidence 



























































 
   .........250.........260.........270.........280.........290.........300
Sequence  FMGTTVVSGTAQAMVIATGANTWFGQLAGRVSEQESEPNAFQQGISRVSMLLIRFMLVMA
Secondary structure 












SS confidence 



























































Disorder 































????????



















Disorder confidence 



























































 
   .........310.........320.........330.........340.........350.........360
Sequence  PVVLLINGYTKGDWWEAALFALSVAVGLTPEMLPMIVTSTLARGAVKLSKQKVIVKHLDA
Secondary structure 






SS confidence 



























































Disorder 



























































Disorder confidence 



























































 
   .........370.........380.........390.........400.........410.........420
Sequence  IQNFGAMDILCTDKTGTLTQDKIVLENHTDISGKTSERVLHSAWLNSHYQTGLKNLLDTA
Secondary structure 




























SS confidence 



























































Disorder 



























































Disorder confidence 



























































 
   .........430.........440.........450.........460.........470.........480
Sequence  VLEGTDEESARSLASRWQKIDEIPFDFERRRMSVVVAENTEHHQLVCKGALQEILNVCSQ
Secondary structure 



















SS confidence 



























































Disorder 


























































?
Disorder confidence 



























































 
   .........490.........500.........510.........520.........530.........540
Sequence  VRHNGEIVPLDDIMLRKIKRVTDTLNRQGLRVVAVATKYLPAREGDYQRADESDLILEGY
Secondary structure 

























SS confidence 



























































Disorder  ?






?































????????










Disorder confidence 



























































 
   .........550.........560.........570.........580.........590.........600
Sequence  IAFLDPPKETTAPALKALKASGITVKILTGDSELVAAKVCHEVGLDAGEVVIGSDIETLS
Secondary structure 






















SS confidence 



























































Disorder 














































?









?
Disorder confidence 



























































 
   .........610.........620.........630.........640.........650.........660
Sequence  DDELANLAQRTTLFARLTPMHKERIVTLLKREGHVVGFMGDGINDAPALRAADIGISVDG
Secondary structure 
















SS confidence 



























































Disorder 



























































Disorder confidence 



























































 
   .........670.........680.........690.........700.........710.........720
Sequence  AVDIAREAADIILLEKSLMVLEEGVIEGRRTFANMLKYIKMTASSNFGNVFSVLVASAFL
Secondary structure 







SS confidence 



























































Disorder 


























































?
Disorder confidence 



























































 
   .........730.........740.........750.........760.........770.........780
Sequence  PFLPMLPLHLLIQNLLYDVSQVAIPFDNVDDEQIQKPQRWNPADLGRFMIFFGPISSIFD
Secondary structure 



















SS confidence 



























































Disorder  ?


















??






??

????

???

















Disorder confidence 



























































 
   .........790.........800.........810.........820.........830.........840
Sequence  ILTFCLMWWVFHANTPETQTLFQSGWFVVGLLSQTLIVHMIRTRRVPFIQSCASWPLMIM
Secondary structure 
















SS confidence 



























































Disorder 











?

???
























???????


?





Disorder confidence 



























































 
   .........850.........860.........870.........880.........890........
Sequence  TVIVMIVGIALPFSPLASYLQLQALPLSYFPWLVAILAGYMTLTQLVKGFYSRRYGWQ
Secondary structure 








SS confidence 

























































Disorder 




















































?????
Disorder confidence 

























































 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2zxe chain A

3D model

Region: 43 - 897
Aligned: 846
Modelled: 849
Confidence: 100.0%
Identity: 28%
PDB header:hydrolase/transport protein
Chain: A: PDB Molecule:na, k-atpase alpha subunit;
PDBTitle: crystal structure of the sodium - potassium pump in the e2.2k+.pi2 state

Phyre2

PDB 3b9b chain A

3D model

Region: 43 - 896
Aligned: 848
Modelled: 853
Confidence: 100.0%
Identity: 25%
PDB header:hydrolase
Chain: A: PDB Molecule:sarcoplasmic/endoplasmic reticulum calcium
PDBTitle: structure of the e2 beryllium fluoride complex of the serca2 ca2+-atpase

Phyre2

PDB 3ixz chain A

3D model

Region: 29 - 898
Aligned: 860
Modelled: 870
Confidence: 100.0%
Identity: 27%
PDB header:hydrolase
Chain: A: PDB Molecule:potassium-transporting atpase alpha;
PDBTitle: pig gastric h+/k+-atpase complexed with aluminium fluoride

Phyre2

PDB 3b8e chain C

3D model

Region: 28 - 897
Aligned: 861
Modelled: 870
Confidence: 100.0%
Identity: 27%
PDB header:hydrolase/transport protein
Chain: C: PDB Molecule:sodium/potassium-transporting atpase subunit
PDBTitle: crystal structure of the sodium-potassium pump

Phyre2

PDB 1mhs chain A

3D model

Region: 55 - 886
Aligned: 792
Modelled: 792
Confidence: 100.0%
Identity: 25%
PDB header:membrane protein, proton transport
Chain: A: PDB Molecule:plasma membrane atpase;
PDBTitle: model of neurospora crassa proton atpase

Phyre2

PDB 3b8c chain B

3D model

Region: 43 - 893
Aligned: 809
Modelled: 838
Confidence: 100.0%
Identity: 26%
PDB header:hydrolase
Chain: B: PDB Molecule:atpase 2, plasma membrane-type;
PDBTitle: crystal structure of a plasma membrane proton pump

Phyre2

PDB 3rfu chain C

3D model

Region: 88 - 743
Aligned: 567
Modelled: 588
Confidence: 100.0%
Identity: 24%
PDB header:hydrolase, membrane protein
Chain: C: PDB Molecule:copper efflux atpase;
PDBTitle: crystal structure of a copper-transporting pib-type atpase

Phyre2

PDB 3j09 chain A

3D model

Region: 117 - 743
Aligned: 533
Modelled: 567
Confidence: 100.0%
Identity: 25%
PDB header:hydrolase, metal transport
Chain: A: PDB Molecule:copper-exporting p-type atpase a;
PDBTitle: high resolution helical reconstruction of the bacterial p-type atpase2 copper transporter copa

Phyre2

PDB 3j08 chain A

3D model

Region: 117 - 746
Aligned: 536
Modelled: 563
Confidence: 100.0%
Identity: 25%
PDB header:hydrolase, metal transport
Chain: A: PDB Molecule:copper-exporting p-type atpase a;
PDBTitle: high resolution helical reconstruction of the bacterial p-type atpase2 copper transporter copa

Phyre2

PDB 1wpg chain A domain 4

3D model

Region: 43 - 895
Aligned: 413
Modelled: 413
Confidence: 100.0%
Identity: 28%
Fold: Calcium ATPase, transmembrane domain M
Superfamily: Calcium ATPase, transmembrane domain M
Family: Calcium ATPase, transmembrane domain M

Phyre2

PDB 2b8e chain B

3D model

Region: 364 - 686
Aligned: 239
Modelled: 270
Confidence: 100.0%
Identity: 33%
PDB header:membrane protein
Chain: B: PDB Molecule:cation-transporting atpase;
PDBTitle: copa atp binding domain

Phyre2

PDB 2iye chain C

3D model

Region: 345 - 687
Aligned: 244
Modelled: 253
Confidence: 100.0%
Identity: 28%
PDB header:hydrolase
Chain: C: PDB Molecule:copper-transporting atpase;
PDBTitle: structure of catalytic cpx-atpase domain copb-b

Phyre2

PDB 1wpg chain A domain 2

3D model

Region: 533 - 688
Aligned: 156
Modelled: 156
Confidence: 100.0%
Identity: 31%
Fold: HAD-like
Superfamily: HAD-like
Family: Meta-cation ATPase, catalytic domain P

Phyre2

PDB 2b8e chain A domain 1

3D model

Region: 534 - 686
Aligned: 119
Modelled: 128
Confidence: 100.0%
Identity: 41%
Fold: HAD-like
Superfamily: HAD-like
Family: Meta-cation ATPase, catalytic domain P

Phyre2

PDB 1y8a chain A domain 1

3D model

Region: 544 - 717
Aligned: 173
Modelled: 174
Confidence: 100.0%
Identity: 17%
Fold: HAD-like
Superfamily: HAD-like
Family: AF1437-like

Phyre2

PDB 3p96 chain A

3D model

Region: 321 - 698
Aligned: 312
Modelled: 335
Confidence: 99.9%
Identity: 18%
PDB header:hydrolase
Chain: A: PDB Molecule:phosphoserine phosphatase serb;
PDBTitle: crystal structure of phosphoserine phosphatase serb from mycobacterium2 avium, native form

Phyre2

PDB 3gwi chain A

3D model

Region: 383 - 545
Aligned: 163
Modelled: 163
Confidence: 99.9%
Identity: 100%
PDB header:hydrolase
Chain: A: PDB Molecule:magnesium-transporting atpase, p-type 1;
PDBTitle: crystal structure of mg-atpase nucleotide binding domain

Phyre2

PDB 1mo7 chain A

3D model

Region: 380 - 547
Aligned: 168
Modelled: 168
Confidence: 99.9%
Identity: 25%
Fold: Metal cation-transporting ATPase, ATP-binding domain N
Superfamily: Metal cation-transporting ATPase, ATP-binding domain N
Family: Metal cation-transporting ATPase, ATP-binding domain N

Phyre2

PDB 3n28 chain A

3D model

Region: 321 - 694
Aligned: 289
Modelled: 303
Confidence: 99.9%
Identity: 15%
PDB header:hydrolase
Chain: A: PDB Molecule:phosphoserine phosphatase;
PDBTitle: crystal structure of probable phosphoserine phosphatase from vibrio2 cholerae, unliganded form

Phyre2

PDB 1wpg chain A domain 1

3D model

Region: 155 - 271
Aligned: 111
Modelled: 117
Confidence: 99.9%
Identity: 33%
Fold: Double-stranded beta-helix
Superfamily: Calcium ATPase, transduction domain A
Family: Calcium ATPase, transduction domain A

Phyre2
1

c2zxeA_
2

c3b9bA_
3

c3ixzA_
4

c3b8eC_
5

c1mhsA_
6

c3b8cB_
7

c3rfuC_
8

c3j09A_
9

c3j08A_
10

d1wpga4
11

c2b8eB_
12

c2iyeC_
13

d1wpga2
14

d2b8ea1
15

d1y8aa1
16

c3p96A_
17

c3gwiA_
18

d1mo7a_
19

c3n28A_
20

d1wpga1
21



22



23



24



25



26



27



28



29



30



31



32



33



34



35



36



37



38



39



40



41



42



43



44



45



46



47



48



49



50



51



52



53



54



55



56



57



58



59



60



61



62



63



64



65



66



67



68



69



70



71



72



73



74



75



76



77



78



79



80



81



82



83



84



85



86



87



88



89



90



91



92



93



94



95



96



97



98



99



100



101



102



103



104



105



106



107



108



109



110



111



112



113



114



115



116



117



118



119



120



121



122



123



124



125



126



127



128



129



130



131



132



133



134



135



136



137



138



139



140



141



142



143



144



145



146



147



148



149



150



151



152



153



154



155



156



157



158



159



160



161



162



163



164



165



166



167



168



169



170



171



172



173



174



175



176



177



178



179



180



181



182



183



184



185



186



187



188



189



190



191



192



193



194



195



196



197



198



199



200



201



202



203



204



205



206



207



208



209



210



211



212



213



214



215



216



217



218



219



220



221



222



223



224



225



226



227



228



229



230



231



232



233



234



235



236



237



238



239



240



241



242



243



244



245



246



247



248



249



250



251



252



253



254



255



256



257



258



259



260



261



262



263



264



265



266



267



268



269



270



271



272



273



274



275



276



277



278



279



280



281



282



283



284



285



286



287



288



289



290



291



292



293



294



295



296



297



298



299



300



301



302



303



304



305



306



307



308



309



310



311



312



313



314



315



316



317



318



319



320



321



322



323



324



325



326



327



328



329



330



331



332



333



334



335



336



337



338



339



340



341



342



343



344



345



346



347



348



349



350



351



352



353



354



355



356



357



358



359



360



361



362



363



364



365



366



367



368



369



370



371



372



373



374



375



376



377



378



379



380



381



382






Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2zxeA_



100.0 28 PDB header:hydrolase/transport protein
Chain: A: PDB Molecule:na, k-atpase alpha subunit;
PDBTitle: crystal structure of the sodium - potassium pump in the e2.2k+.pi2 state
2c3b9bA_



100.0 25 PDB header:hydrolase
Chain: A: PDB Molecule:sarcoplasmic/endoplasmic reticulum calcium
PDBTitle: structure of the e2 beryllium fluoride complex of the serca2 ca2+-atpase
3c3ixzA_



100.0 27 PDB header:hydrolase
Chain: A: PDB Molecule:potassium-transporting atpase alpha;
PDBTitle: pig gastric h+/k+-atpase complexed with aluminium fluoride
4c3b8eC_



100.0 27 PDB header:hydrolase/transport protein
Chain: C: PDB Molecule:sodium/potassium-transporting atpase subunit
PDBTitle: crystal structure of the sodium-potassium pump
5c1mhsA_



100.0 25 PDB header:membrane protein, proton transport
Chain: A: PDB Molecule:plasma membrane atpase;
PDBTitle: model of neurospora crassa proton atpase
6c3b8cB_



100.0 26 PDB header:hydrolase
Chain: B: PDB Molecule:atpase 2, plasma membrane-type;
PDBTitle: crystal structure of a plasma membrane proton pump
7c3rfuC_



100.0 24 PDB header:hydrolase, membrane protein
Chain: C: PDB Molecule:copper efflux atpase;
PDBTitle: crystal structure of a copper-transporting pib-type atpase
8c3j09A_



100.0 25 PDB header:hydrolase, metal transport
Chain: A: PDB Molecule:copper-exporting p-type atpase a;
PDBTitle: high resolution helical reconstruction of the bacterial p-type atpase2 copper transporter copa
9c3j08A_



100.0 25 PDB header:hydrolase, metal transport
Chain: A: PDB Molecule:copper-exporting p-type atpase a;
PDBTitle: high resolution helical reconstruction of the bacterial p-type atpase2 copper transporter copa
10d1wpga4



100.0 28 Fold:Calcium ATPase, transmembrane domain M
Superfamily:Calcium ATPase, transmembrane domain M
Family:Calcium ATPase, transmembrane domain M
11c2b8eB_



100.0 33 PDB header:membrane protein
Chain: B: PDB Molecule:cation-transporting atpase;
PDBTitle: copa atp binding domain
12c2iyeC_



100.0 28 PDB header:hydrolase
Chain: C: PDB Molecule:copper-transporting atpase;
PDBTitle: structure of catalytic cpx-atpase domain copb-b
13d1wpga2



100.0 31 Fold:HAD-like
Superfamily:HAD-like
Family:Meta-cation ATPase, catalytic domain P
14d2b8ea1



100.0 41 Fold:HAD-like
Superfamily:HAD-like
Family:Meta-cation ATPase, catalytic domain P
15d1y8aa1



100.0 17 Fold:HAD-like
Superfamily:HAD-like
Family:AF1437-like
16c3p96A_



99.9 18 PDB header:hydrolase
Chain: A: PDB Molecule:phosphoserine phosphatase serb;
PDBTitle: crystal structure of phosphoserine phosphatase serb from mycobacterium2 avium, native form
17c3gwiA_



99.9 100 PDB header:hydrolase
Chain: A: PDB Molecule:magnesium-transporting atpase, p-type 1;
PDBTitle: crystal structure of mg-atpase nucleotide binding domain
18d1mo7a_



99.9 25 Fold:Metal cation-transporting ATPase, ATP-binding domain N
Superfamily:Metal cation-transporting ATPase, ATP-binding domain N
Family:Metal cation-transporting ATPase, ATP-binding domain N
19c3n28A_



99.9 15 PDB header:hydrolase
Chain: A: PDB Molecule:phosphoserine phosphatase;
PDBTitle: crystal structure of probable phosphoserine phosphatase from vibrio2 cholerae, unliganded form
20d1wpga1



99.9 33 Fold:Double-stranded beta-helix
Superfamily:Calcium ATPase, transduction domain A
Family:Calcium ATPase, transduction domain A
21d1wpga3



not modelled 99.9 22 Fold:Metal cation-transporting ATPase, ATP-binding domain N
Superfamily:Metal cation-transporting ATPase, ATP-binding domain N
Family:Metal cation-transporting ATPase, ATP-binding domain N
22d1q3ia_



not modelled 99.9 24 Fold:Metal cation-transporting ATPase, ATP-binding domain N
Superfamily:Metal cation-transporting ATPase, ATP-binding domain N
Family:Metal cation-transporting ATPase, ATP-binding domain N
23c2hc8A_



not modelled 99.9 26 PDB header:transport protein
Chain: A: PDB Molecule:cation-transporting atpase, p-type;
PDBTitle: structure of the a. fulgidus copa a-domain
24c2kijA_



not modelled 99.8 25 PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting atpase 1;
PDBTitle: solution structure of the actuator domain of the copper-2 transporting atpase atp7a
25c3n07B_



not modelled 99.5 19 PDB header:hydrolase
Chain: B: PDB Molecule:3-deoxy-d-manno-octulosonate 8-phosphate phosphatase;
PDBTitle: structure of putative 3-deoxy-d-manno-octulosonate 8-phosphate2 phosphatase from vibrio cholerae
26c2r8zC_



not modelled 99.5 18 PDB header:hydrolase
Chain: C: PDB Molecule:3-deoxy-d-manno-octulosonate 8-phosphate phosphatase;
PDBTitle: crystal structure of yrbi phosphatase from escherichia coli in complex2 with a phosphate and a calcium ion
27c2p9jH_



not modelled 99.5 22 PDB header:structural genomics, unknown function
Chain: H: PDB Molecule:hypothetical protein aq2171;
PDBTitle: crystal structure of aq2171 from aquifex aeolicus
28c3mmzA_



not modelled 99.5 18 PDB header:hydrolase
Chain: A: PDB Molecule:putative had family hydrolase;
PDBTitle: crystal structure of putative had family hydrolase from streptomyces2 avermitilis ma-4680
29c3mn1B_



not modelled 99.5 24 PDB header:hydrolase
Chain: B: PDB Molecule:probable yrbi family phosphatase;
PDBTitle: crystal structure of probable yrbi family phosphatase from pseudomonas2 syringae pv.phaseolica 1448a
30d1k1ea_



not modelled 99.4 21 Fold:HAD-like
Superfamily:HAD-like
Family:Probable phosphatase YrbI
31c3l7yA_



not modelled 99.4 18 PDB header:hydrolase
Chain: A: PDB Molecule:putative uncharacterized protein smu.1108c;
PDBTitle: the crystal structure of smu.1108c from streptococcus mutans ua159
32c3ewiB_



not modelled 99.4 16 PDB header:transferase
Chain: B: PDB Molecule:n-acylneuraminate cytidylyltransferase;
PDBTitle: structural analysis of the c-terminal domain of murine cmp-2 sialic acid synthetase
33d1l6ra_



not modelled 99.4 18 Fold:HAD-like
Superfamily:HAD-like
Family:Predicted hydrolases Cof
34d1wr8a_



not modelled 99.3 23 Fold:HAD-like
Superfamily:HAD-like
Family:Predicted hydrolases Cof
35c3n1uA_



not modelled 99.3 21 PDB header:hydrolase
Chain: A: PDB Molecule:hydrolase, had superfamily, subfamily iii a;
PDBTitle: structure of putative had superfamily (subfamily iii a) hydrolase from2 legionella pneumophila
36d1rkqa_



not modelled 99.3 19 Fold:HAD-like
Superfamily:HAD-like
Family:Predicted hydrolases Cof
37c3e8mD_



not modelled 99.3 23 PDB header:transferase
Chain: D: PDB Molecule:acylneuraminate cytidylyltransferase;
PDBTitle: structure-function analysis of 2-keto-3-deoxy-d-glycero-d-galacto-2 nononate-9-phosphate (kdn) phosphatase defines a new clad within the3 type c0 had subfamily
38c3m1yA_



not modelled 99.2 26 PDB header:hydrolase
Chain: A: PDB Molecule:phosphoserine phosphatase (serb);
PDBTitle: crystal structure of a phosphoserine phosphatase (serb) from2 helicobacter pylori
39c3daoB_



not modelled 99.2 20 PDB header:hydrolase
Chain: B: PDB Molecule:putative phosphatse;
PDBTitle: crystal structure of a putative phosphatse (eubrec_1417) from2 eubacterium rectale at 1.80 a resolution
40d1j97a_



not modelled 99.2 30 Fold:HAD-like
Superfamily:HAD-like
Family:Phosphoserine phosphatase
41d1rlma_



not modelled 99.2 21 Fold:HAD-like
Superfamily:HAD-like
Family:Predicted hydrolases Cof
42d1nrwa_



not modelled 99.2 25 Fold:HAD-like
Superfamily:HAD-like
Family:Predicted hydrolases Cof
43c2qyhD_



not modelled 99.2 24 PDB header:structural genomics, unknown function
Chain: D: PDB Molecule:hypothetical conserved protein, gk1056;
PDBTitle: crystal structure of the hypothetical protein (gk1056) from2 geobacillus kaustophilus hta426
44d2b30a1



not modelled 99.1 25 Fold:HAD-like
Superfamily:HAD-like
Family:Predicted hydrolases Cof
45c3dnpA_



not modelled 99.1 27 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:stress response protein yhax;
PDBTitle: crystal structure of stress response protein yhax from bacillus2 subtilis
46c3r4cA_



not modelled 99.1 24 PDB header:hydrolase
Chain: A: PDB Molecule:hydrolase, haloacid dehalogenase-like hydrolase;
PDBTitle: divergence of structure and function among phosphatases of the2 haloalkanoate (had) enzyme superfamily: analysis of bt1666 from3 bacteroides thetaiotaomicron
47c3pgvB_



not modelled 99.1 19 PDB header:hydrolase
Chain: B: PDB Molecule:haloacid dehalogenase-like hydrolase;
PDBTitle: crystal structure of a haloacid dehalogenase-like hydrolase2 (kpn_04322) from klebsiella pneumoniae subsp. pneumoniae mgh 78578 at3 2.39 a resolution
48c3fzqA_



not modelled 99.1 18 PDB header:hydrolase
Chain: A: PDB Molecule:putative hydrolase;
PDBTitle: crystal structure of putative haloacid dehalogenase-like hydrolase2 (yp_001086940.1) from clostridium difficile 630 at 2.10 a resolution
49d2rbka1



not modelled 99.0 23 Fold:HAD-like
Superfamily:HAD-like
Family:Predicted hydrolases Cof
50c3niwA_



not modelled 99.0 25 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:haloacid dehalogenase-like hydrolase;
PDBTitle: crystal structure of a haloacid dehalogenase-like hydrolase from2 bacteroides thetaiotaomicron
51d1rkua_



not modelled 99.0 18 Fold:HAD-like
Superfamily:HAD-like
Family:Homoserine kinase ThrH
52d1nnla_



not modelled 98.9 16 Fold:HAD-like
Superfamily:HAD-like
Family:Phosphoserine phosphatase
53d1nf2a_



not modelled 98.9 22 Fold:HAD-like
Superfamily:HAD-like
Family:Predicted hydrolases Cof
54c2kmvA_



not modelled 98.8 15 PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting atpase 1;
PDBTitle: solution structure of the nucleotide binding domain of the2 human menkes protein in the atp-free form
55d2feaa1



not modelled 98.8 10 Fold:HAD-like
Superfamily:HAD-like
Family:MtnX-like
56c3gygA_



not modelled 98.6 18 PDB header:hydrolase
Chain: A: PDB Molecule:ntd biosynthesis operon putative hydrolase ntdb;
PDBTitle: crystal structure of yhjk (haloacid dehalogenase-like hydrolase2 protein) from bacillus subtilis
57d1s2oa1



not modelled 98.6 19 Fold:HAD-like
Superfamily:HAD-like
Family:Predicted hydrolases Cof
58c3fvvA_



not modelled 98.6 25 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: the crystal structure of the protein with unknown function from2 bordetella pertussis tohama i
59c2koyA_



not modelled 98.6 15 PDB header:metal transport
Chain: A: PDB Molecule:copper-transporting atpase 2;
PDBTitle: structure of the e1064a mutant of the n-domain of wilson disease2 associated protein
60d2a29a1



not modelled 98.5 16 Fold:Metal cation-transporting ATPase, ATP-binding domain N
Superfamily:Metal cation-transporting ATPase, ATP-binding domain N
Family:Metal cation-transporting ATPase, ATP-binding domain N
61d1xvia_



not modelled 98.4 28 Fold:HAD-like
Superfamily:HAD-like
Family:Predicted hydrolases Cof
62c1xviA_



not modelled 98.4 28 PDB header:hydrolase
Chain: A: PDB Molecule:putative mannosyl-3-phosphoglycerate phosphatase;
PDBTitle: crystal structure of yedp, phosphatase-like domain protein2 from escherichia coli k12
63d1wzca1



not modelled 98.4 23 Fold:HAD-like
Superfamily:HAD-like
Family:Predicted hydrolases Cof
64c3kd3A_



not modelled 98.4 9 PDB header:unknown function
Chain: A: PDB Molecule:phosphoserine phosphohydrolase-like protein;
PDBTitle: crystal structure of a phosphoserine phosphohydrolase-like protein2 from francisella tularensis subsp. tularensis schu s4
65c2i55C_



not modelled 98.3 24 PDB header:isomerase
Chain: C: PDB Molecule:phosphomannomutase;
PDBTitle: complex of glucose-1,6-bisphosphate with phosphomannomutase from2 leishmania mexicana
66d2vkqa1



not modelled 98.1 18 Fold:HAD-like
Superfamily:HAD-like
Family:Pyrimidine 5'-nucleotidase (UMPH-1)
67c1y8aA_



not modelled 98.0 19 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein af1437;
PDBTitle: structure of gene product af1437 from archaeoglobus fulgidus
68c2voyH_



not modelled 98.0 32 PDB header:hydrolase
Chain: H: PDB Molecule:sarcoplasmic/endoplasmic reticulum calcium
PDBTitle: cryoem model of copa, the copper transporting atpase from2 archaeoglobus fulgidus
69c2voyB_



not modelled 98.0 21 PDB header:hydrolase
Chain: B: PDB Molecule:sarcoplasmic/endoplasmic reticulum calcium
PDBTitle: cryoem model of copa, the copper transporting atpase from2 archaeoglobus fulgidus
70c3iruA_



not modelled 97.8 21 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:phoshonoacetaldehyde hydrolase like protein;
PDBTitle: crystal structure of phoshonoacetaldehyde hydrolase like protein from2 oleispira antarctica
71d1u02a_



not modelled 97.8 14 Fold:HAD-like
Superfamily:HAD-like
Family:Trehalose-phosphatase
72d2fuea1



not modelled 97.8 23 Fold:HAD-like
Superfamily:HAD-like
Family:Predicted hydrolases Cof
73d1qyia_



not modelled 97.7 21 Fold:HAD-like
Superfamily:HAD-like
Family:Hypothetical protein MW1667 (SA1546)
74d1zs9a1



not modelled 97.7 20 Fold:HAD-like
Superfamily:HAD-like
Family:Enolase-phosphatase E1
75d1swva_



not modelled 97.7 21 Fold:HAD-like
Superfamily:HAD-like
Family:Phosphonoacetaldehyde hydrolase-like
76d2amya1



not modelled 97.6 20 Fold:HAD-like
Superfamily:HAD-like
Family:Predicted hydrolases Cof
77c3mpoD_



not modelled 97.6 27 PDB header:hydrolase
Chain: D: PDB Molecule:predicted hydrolase of the had superfamily;
PDBTitle: the crystal structure of a hydrolase from lactobacillus brevis
78d2bdua1



not modelled 97.6 18 Fold:HAD-like
Superfamily:HAD-like
Family:Pyrimidine 5'-nucleotidase (UMPH-1)
79c3s6jC_



not modelled 97.4 17 PDB header:hydrolase
Chain: C: PDB Molecule:hydrolase, haloacid dehalogenase-like family;
PDBTitle: the crystal structure of a hydrolase from pseudomonas syringae
80c2odaB_



not modelled 97.4 16 PDB header:protein binding
Chain: B: PDB Molecule:hypothetical protein pspto_2114;
PDBTitle: crystal structure of pspto_2114
81c2arfA_



not modelled 97.3 13 PDB header:hydrolase
Chain: A: PDB Molecule:wilson disease atpase;
PDBTitle: solution structure of the wilson atpase n-domain in the2 presence of atp
82c3mc1A_



not modelled 97.2 17 PDB header:hydrolase
Chain: A: PDB Molecule:predicted phosphatase, had family;
PDBTitle: crystal structure of a predicted phosphatase from2 clostridium acetobutylicum
83c3m9lA_



not modelled 97.1 17 PDB header:hydrolase
Chain: A: PDB Molecule:hydrolase, haloacid dehalogenase-like family;
PDBTitle: crystal structure of probable had family hydrolase from2 pseudomonas fluorescens pf-5
84c2voyK_



not modelled 97.1 35 PDB header:hydrolase
Chain: K: PDB Molecule:sarcoplasmic/endoplasmic reticulum calcium
PDBTitle: cryoem model of copa, the copper transporting atpase from2 archaeoglobus fulgidus
85c3dv9A_



not modelled 97.0 17 PDB header:isomerase
Chain: A: PDB Molecule:beta-phosphoglucomutase;
PDBTitle: putative beta-phosphoglucomutase from bacteroides vulgatus.
86c2pibA_



not modelled 96.9 17 PDB header:hydrolase
Chain: A: PDB Molecule:phosphorylated carbohydrates phosphatase tm_1254;
PDBTitle: crystal structure of putative beta-phosphoglucomutase from2 thermotoga maritima
87c3pdwA_



not modelled 96.9 21 PDB header:hydrolase
Chain: A: PDB Molecule:uncharacterized hydrolase yutf;
PDBTitle: crystal structure of putative p-nitrophenyl phosphatase from bacillus2 subtilis
88c3d6jA_



not modelled 96.7 26 PDB header:hydrolase
Chain: A: PDB Molecule:putative haloacid dehalogenase-like hydrolase;
PDBTitle: crystal structure of putative haloacid dehalogenase-like hydrolase2 from bacteroides fragilis
89c2yy6B_



not modelled 96.7 19 PDB header:hydrolase
Chain: B: PDB Molecule:phosphoglycolate phosphatase;
PDBTitle: crystal structure of the phosphoglycolate phosphatase from aquifex2 aeolicus vf5
90c3ib6B_



not modelled 96.6 18 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of an uncharacterized protein from listeria2 monocytogenes serotype 4b
91d1u7pa_



not modelled 96.6 14 Fold:HAD-like
Superfamily:HAD-like
Family:Magnesium-dependent phosphatase-1, Mdp1
92c2hx1D_



not modelled 96.5 16 PDB header:hydrolase
Chain: D: PDB Molecule:predicted sugar phosphatases of the had
PDBTitle: crystal structure of possible sugar phosphatase, had2 superfamily (zp_00311070.1) from cytophaga hutchinsonii3 atcc 33406 at 2.10 a resolution
93c2hi0B_



not modelled 96.4 16 PDB header:hydrolase
Chain: B: PDB Molecule:putative phosphoglycolate phosphatase;
PDBTitle: crystal structure of putative phosphoglycolate phosphatase2 (yp_619066.1) from lactobacillus delbrueckii subsp. bulgaricus atcc3 baa-365 at 1.51 a resolution
94d2hsza1



not modelled 96.4 18 Fold:HAD-like
Superfamily:HAD-like
Family:beta-Phosphoglucomutase-like
95d2go7a1



not modelled 96.2 13 Fold:HAD-like
Superfamily:HAD-like
Family:beta-Phosphoglucomutase-like
96d2gmwa1



not modelled 96.2 20 Fold:HAD-like
Superfamily:HAD-like
Family:Histidinol phosphatase-like
97c3esqA_



not modelled 96.2 20 PDB header:hydrolase
Chain: A: PDB Molecule:d,d-heptose 1,7-bisphosphate phosphatase;
PDBTitle: crystal structure of calcium-bound d,d-heptose 1.7-2 bisphosphate phosphatase from e. coli
98d2ah5a1



not modelled 96.2 13 Fold:HAD-like
Superfamily:HAD-like
Family:beta-Phosphoglucomutase-like
99c2qltA_



not modelled 96.2 20 PDB header:hydrolase
Chain: A: PDB Molecule:(dl)-glycerol-3-phosphatase 1;
PDBTitle: crystal structure of an isoform of dl-glycerol-3-phosphatase, rhr2p,2 from saccharomyces cerevisiae
100d1z5ga1



not modelled 96.1 27 Fold:HAD-like
Superfamily:HAD-like
Family:Class B acid phosphatase, AphA
101c2no5B_



not modelled 95.9 17 PDB header:hydrolase
Chain: B: PDB Molecule:(s)-2-haloacid dehalogenase iva;
PDBTitle: crystal structure analysis of a dehalogenase with intermediate complex
102d1te2a_



not modelled 95.8 21 Fold:HAD-like
Superfamily:HAD-like
Family:beta-Phosphoglucomutase-like
103c2cftA_



not modelled 95.8 22 PDB header:phosphatase
Chain: A: PDB Molecule:pyridoxal phosphate phosphatase;
PDBTitle: crystal structure of human pyridoxal 5'-phosphate2 phosphatase with its substrate
104c3et4A_



not modelled 95.8 16 PDB header:hydrolase
Chain: A: PDB Molecule:outer membrane protein p4, nadp phosphatase;
PDBTitle: structure of recombinant haemophilus influenzae e(p4) acid phosphatase
105c3pctA_



not modelled 95.6 19 PDB header:hydrolase
Chain: A: PDB Molecule:class c acid phosphatase;
PDBTitle: structure of the class c acid phosphatase from pasteurella multocida
106c2pr7A_



not modelled 95.6 17 PDB header:hydrolase
Chain: A: PDB Molecule:haloacid dehalogenase/epoxide hydrolase family;
PDBTitle: crystal structure of uncharacterized protein (np_599989.1) from2 corynebacterium glutamicum atcc 13032 kitasato at 1.44 a resolution
107d1zrna_



not modelled 95.5 19 Fold:HAD-like
Superfamily:HAD-like
Family:HAD-related
108d1wvia_



not modelled 95.4 18 Fold:HAD-like
Superfamily:HAD-like
Family:NagD-like
109d2fdra1



not modelled 95.4 16 Fold:HAD-like
Superfamily:HAD-like
Family:beta-Phosphoglucomutase-like
110d1zd3a1



not modelled 95.4 19 Fold:HAD-like
Superfamily:HAD-like
Family:YihX-like
111c2hoqA_



not modelled 95.4 14 PDB header:hydrolase
Chain: A: PDB Molecule:putative had-hydrolase ph1655;
PDBTitle: crystal structure of the probable haloacid dehalogenase (ph1655) from2 pyrococcus horikoshii ot3
112d2hcfa1



not modelled 95.2 17 Fold:HAD-like
Superfamily:HAD-like
Family:beta-Phosphoglucomutase-like
113d2fi1a1



not modelled 95.1 16 Fold:HAD-like
Superfamily:HAD-like
Family:Phosphonoacetaldehyde hydrolase-like
114d1vjra_



not modelled 95.0 24 Fold:HAD-like
Superfamily:HAD-like
Family:NagD-like
115d1ydfa1



not modelled 95.0 17 Fold:HAD-like
Superfamily:HAD-like
Family:NagD-like
116d1cr6a1



not modelled 95.0 20 Fold:HAD-like
Superfamily:HAD-like
Family:YihX-like
117d2b82a1



not modelled 94.9 21 Fold:HAD-like
Superfamily:HAD-like
Family:Class B acid phosphatase, AphA
118d1x42a1



not modelled 94.8 19 Fold:HAD-like
Superfamily:HAD-like
Family:HAD-related
119c1zjjA_



not modelled 94.3 21 PDB header:hydrolase
Chain: A: PDB Molecule:hypothetical protein ph1952;
PDBTitle: crystal structure of hypothetical protein ph1952 from pyrococcus2 horikoshii ot3
120c3l5kA_



not modelled 94.2 13 PDB header:hydrolase
Chain: A: PDB Molecule:haloacid dehalogenase-like hydrolase domain-
PDBTitle: the crystal structure of human haloacid dehalogenase-like2 hydrolase domain containing 1a (hdhd1a)

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0