Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	P	K	Y	R	S	A	T	T	T	H	G	R	N	M	A	G	A	R	A	L	W	R	A	T	G	M	T	D	A	D	F	G	K	P	I	I	A	V	V	N	S	F	T	Q	F	V	P	G	H	V	H	L	R	D	L	G	K	L	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?			?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	E	Q	I	E	A	A	G	G	V	A	K	E	F	N	T	I	A	V	D	D	G	I	A	M	G	H	G	G	M	L	Y	S	L	P	S	R	E	L	I	A	D	S	V	E	Y	M	V	N	A	H	C	A	D	A	M	V	C	I	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		N	C	D	K	I	T	P	G	M	L	M	A	S	L	R	L	N	I	P	V	I	F	V	S	G	G	P	M	E	A	G	K	T	K	L	S	D	Q	I	I	K	L	D	L	V	D	A	M	I	Q	G	A	D	P	K	V	S	D	S	Q
Secondary structure
SS confidence
Disorder																																	?	?	?	?	?	?				?											?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		S	D	Q	V	E	R	S	A	C	P	T	C	G	S	C	S	G	M	F	T	A	N	S	M	N	C	L	T	E	A	L	G	L	S	Q	P	G	N	G	S	L	L	A	T	H	A	D	R	K	Q	L	F	L	N	A	G	K	R	I	V
Secondary structure
SS confidence
Disorder																																										?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		E	L	T	K	R	Y	Y	E	Q	N	D	E	S	A	L	P	R	N	I	A	S	K	A	A	F	E	N	A	M	T	L	D	I	A	M	G	G	S	T	N	T	V	L	H	L	L	A	A	A	Q	E	A	E	I	D	F	T	M	S	D
Secondary structure
SS confidence
Disorder						?	?			?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		I	D	K	L	S	R	K	V	P	Q	L	C	K	V	A	P	S	T	Q	K	Y	H	M	E	D	V	H	R	A	G	G	V	I	G	I	L	G	E	L	D	R	A	G	L	L	N	R	D	V	K	N	V	L	G	L	T	L	P	Q	T
Secondary structure
SS confidence
Disorder																																												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		L	E	Q	Y	D	V	M	L	T	Q	D	D	A	V	K	N	M	F	R	A	G	P	A	G	I	R	T	T	Q	A	F	S	Q	D	C	R	W	D	T	L	D	D	D	R	A	N	G	C	I	R	S	L	E	H	A	Y	S	K	D	G
Secondary structure
SS confidence
Disorder								?	?	?	?	?	?	?	?	?	?	?		?	?	?	?	?	?	?	?	?	?			?	?					?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		G	L	A	V	L	Y	G	N	F	A	E	N	G	C	I	V	K	T	A	G	V	D	D	S	I	L	K	F	T	G	P	A	K	V	Y	E	S	Q	D	D	A	V	E	A	I	L	G	G	K	V	V	A	G	D	V	V	V	I	R	Y
Secondary structure
SS confidence
Disorder																								?	?																									?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		E	G	P	K	G	G	P	G	M	Q	E	M	L	Y	P	T	S	F	L	K	S	M	G	L	G	K	A	C	A	L	I	T	D	G	R	F	S	G	G	T	S	G	L	S	I	G	H	V	S	P	E	A	A	S	G	G	S	I	G	L
Secondary structure
SS confidence
Disorder																						?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence		I	E	D	G	D	L	I	A	I	D	I	P	N	R	G	I	Q	L	Q	V	S	D	A	E	L	A	A	R	R	E	A	Q	D	A	R	G	D	K	A	W	T	P	K	N	R	E	R	Q	V	S	F	A	L	R	A	Y	A	S	L	A
Secondary structure
SS confidence
Disorder																				?		?											?	?	?	?	?	?	?	?	?	?	?	?	?	?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.
Sequence		T	S	A	D	K	G	A	V	R	D	K	S	K	L	G	G
Secondary structure
SS confidence
Disorder											?				?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2gp4 chain A Region: 65 - 610 Aligned: 472 Modelled: 497 Confidence: 100.0% Identity: 31% PDB header:lyase Chain: A: PDB Molecule:6-phosphogluconate dehydratase; PDBTitle: structure of [fes]cluster-free apo form of 6-phosphogluconate2 dehydratase from shewanella oneidensis Phyre2 PDB 2gp4 chain A domain 2 Region: 50 - 420 Aligned: 307 Modelled: 322 Confidence: 100.0% Identity: 29% Fold: IlvD/EDD N-terminal domain-like Superfamily: IlvD/EDD N-terminal domain-like Family: lvD/EDD N-terminal domain-like Phyre2 PDB 2gp4 chain A domain 1 Region: 421 - 610 Aligned: 180 Modelled: 190 Confidence: 100.0% Identity: 31% Fold: The "swivelling" beta/beta/alpha domain Superfamily: LeuD/IlvD-like Family: IlvD/EDD C-terminal domain-like Phyre2 PDB 1zym chain A domain 2 Region: 439 - 577 Aligned: 115 Modelled: 139 Confidence: 92.0% Identity: 22% Fold: The "swivelling" beta/beta/alpha domain Superfamily: Phosphohistidine domain Family: N-terminal domain of enzyme I of the PEP:sugar phosphotransferase system Phyre2 PDB 3fij chain D Region: 34 - 212 Aligned: 105 Modelled: 123 Confidence: 86.0% Identity: 21% PDB header:structural genomics, unknown function Chain: D: PDB Molecule:lin1909 protein; PDBTitle: crystal structure of a uncharacterized protein lin1909 Phyre2 PDB 1vbg chain A domain 2 Region: 447 - 556 Aligned: 83 Modelled: 94 Confidence: 81.1% Identity: 14% Fold: The "swivelling" beta/beta/alpha domain Superfamily: Phosphohistidine domain Family: Pyruvate phosphate dikinase, central domain Phyre2 PDB 3nxk chain E Region: 34 - 157 Aligned: 113 Modelled: 124 Confidence: 75.7% Identity: 14% PDB header:hydrolase Chain: E: PDB Molecule:cytoplasmic l-asparaginase; PDBTitle: crystal structure of probable cytoplasmic l-asparaginase from2 campylobacter jejuni Phyre2 PDB 1h6z chain A domain 2 Region: 447 - 556 Aligned: 83 Modelled: 94 Confidence: 67.3% Identity: 19% Fold: The "swivelling" beta/beta/alpha domain Superfamily: Phosphohistidine domain Family: Pyruvate phosphate dikinase, central domain Phyre2 PDB 1od5 chain A domain 1 Region: 409 - 487 Aligned: 73 Modelled: 79 Confidence: 65.9% Identity: 23% Fold: Double-stranded beta-helix Superfamily: RmlC-like cupins Family: Germin/Seed storage 7S protein Phyre2 PDB 2et1 chain A domain 1 Region: 415 - 487 Aligned: 69 Modelled: 73 Confidence: 57.9% Identity: 20% Fold: Double-stranded beta-helix Superfamily: RmlC-like cupins Family: Germin/Seed storage 7S protein Phyre2 PDB 2jv2 chain A Region: 541 - 560 Aligned: 20 Modelled: 20 Confidence: 56.8% Identity: 30% PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein ph1500; PDBTitle: solution structure of the n-terminal domain of ph1500 Phyre2 PDB 2pcn chain A Region: 451 - 515 Aligned: 58 Modelled: 65 Confidence: 56.7% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:s-adenosylmethionine:2-demethylmenaquinone PDBTitle: crystal structure of s-adenosylmethionine: 2-dimethylmenaquinone2 methyltransferase (gk_1813) from geobacillus kaustophilus hta426 Phyre2 PDB 2zki chain H Region: 34 - 249 Aligned: 171 Modelled: 190 Confidence: 53.1% Identity: 20% PDB header:transcription Chain: H: PDB Molecule:199aa long hypothetical trp repressor binding PDBTitle: crystal structure of hypothetical trp repressor binding2 protein from sul folobus tokodaii (st0872) Phyre2 PDB 1fui chain A domain 2 Region: 32 - 144 Aligned: 106 Modelled: 113 Confidence: 52.4% Identity: 8% Fold: FucI/AraA N-terminal and middle domains Superfamily: FucI/AraA N-terminal and middle domains Family: L-fucose isomerase, N-terminal and second domains Phyre2 PDB 1pl8 chain A domain 1 Region: 461 - 485 Aligned: 24 Modelled: 25 Confidence: 50.4% Identity: 25% Fold: GroES-like Superfamily: GroES-like Family: Alcohol dehydrogenase-like, N-terminal domain Phyre2 PDB 2q8k chain A Region: 487 - 551 Aligned: 61 Modelled: 65 Confidence: 48.7% Identity: 21% PDB header:transcription Chain: A: PDB Molecule:proliferation-associated protein 2g4; PDBTitle: the crystal structure of ebp1 Phyre2 PDB 2hwg chain A Region: 520 - 573 Aligned: 48 Modelled: 49 Confidence: 48.4% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:phosphoenolpyruvate-protein phosphotransferase; PDBTitle: structure of phosphorylated enzyme i of the2 phosphoenolpyruvate:sugar phosphotransferase system Phyre2 PDB 3ehk chain C Region: 408 - 487 Aligned: 75 Modelled: 80 Confidence: 46.7% Identity: 20% PDB header:plant protein Chain: C: PDB Molecule:prunin; PDBTitle: crystal structure of pru du amandin, an allergenic protein2 from prunus dulcis Phyre2 PDB 1wsa chain A Region: 34 - 157 Aligned: 117 Modelled: 124 Confidence: 46.6% Identity: 15% Fold: Glutaminase/Asparaginase Superfamily: Glutaminase/Asparaginase Family: Glutaminase/Asparaginase Phyre2 PDB 2hi6 chain A domain 1 Region: 541 - 559 Aligned: 19 Modelled: 19 Confidence: 44.3% Identity: 16% Fold: The "swivelling" beta/beta/alpha domain Superfamily: LeuD/IlvD-like Family: AF0055-like Phyre2 1 c2gp4A_ 2 d2gp4a2 3 d2gp4a1 4 d1zyma2 5 c3fijD_ 6 d1vbga2 7 c3nxkE_ 8 d1h6za2 9 d1od5a1 10 d2et1a1 11 c2jv2A_ 12 c2pcnA_ 13 c2zkiH_ 14 d1fuia2 15 d1pl8a1 16 c2q8kA_ 17 c2hwgA_ 18 c3ehkC_ 19 d1wsaa_ 20 d2hi6a1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106