Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	I	F	L	E	N	L	Y	H	S	D	C	Y	F	L	P	I	R	D	N	Q	Q	V	L	V	G	V	E	L	I	T	H	F	S	S	E	D	G	T	V	R	I	P	T	S	R	V	I	A	Q	L	T	E	E	Q	H	W	Q	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																																		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		F	S	E	Q	L	E	L	L	K	S	C	Q	H	F	F	I	Q	H	K	L	F	A	W	L	N	L	T	P	Q	V	A	T	L	L	L	E	R	D	N	Y	A	G	E	L	L	K	Y	P	F	I	E	L	L	I	N	E	N	Y	P	H
Secondary structure
SS confidence
Disorder																																				?	?																								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	N	E	G	K	D	N	R	G	L	L	S	L	S	Q	V	Y	P	L	V	L	G	N	L	G	A	G	N	S	T	M	K	A	V	F	D	G	L	F	T	R	V	M	L	D	K	S	F	I	Q	Q	Q	I	T	H	R	S	F	E	P
Secondary structure
SS confidence
Disorder		?	?	?																																																	?	?	?			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.
Sequence		F	I	R	A	I	Q	A	Q	I	S	P	C	C	N	C	I	I	A	G	G	I	D	T	A	E	I	L	A	Q	I	T	P	F	D	F	H	A	L	Q	G	C	L	W	P	A	V	P	I	N	Q	I	T	T	L	V	Q	R
Secondary structure
SS confidence
Disorder																																																									?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3hvb chain B Region: 1 - 232 Aligned: 230 Modelled: 232 Confidence: 100.0% Identity: 12% PDB header:hydrolase Chain: B: PDB Molecule:protein fimx; PDBTitle: crystal structure of the dual-domain ggdef-eal module of2 fimx from pseudomonas aeruginosa Phyre2 PDB 3s83 chain A Region: 1 - 237 Aligned: 233 Modelled: 237 Confidence: 100.0% Identity: 14% PDB header:signaling protein Chain: A: PDB Molecule:ggdef family protein; PDBTitle: crystal structure of eal domain from caulobacter crescentus cb15 Phyre2 PDB 3hv9 chain A Region: 1 - 231 Aligned: 229 Modelled: 231 Confidence: 100.0% Identity: 12% PDB header:hydrolase Chain: A: PDB Molecule:protein fimx; PDBTitle: crystal structure of fimx eal domain from pseudomonas aeruginosa Phyre2 PDB 3pjw chain A Region: 10 - 228 Aligned: 215 Modelled: 219 Confidence: 100.0% Identity: 17% PDB header:lyase Chain: A: PDB Molecule:cyclic dimeric gmp binding protein; PDBTitle: structure of pseudomonas fluorescence lapd ggdef-eal dual domain, i23 Phyre2 PDB 3gfz chain B Region: 1 - 225 Aligned: 218 Modelled: 225 Confidence: 100.0% Identity: 12% PDB header:hydrolase, signaling protein Chain: B: PDB Molecule:klebsiella pneumoniae blrp1; PDBTitle: klebsiella pneumoniae blrp1 ph 6 manganese/cy-digmp complex Phyre2 PDB 2w27 chain A Region: 1 - 227 Aligned: 220 Modelled: 227 Confidence: 100.0% Identity: 13% PDB header:signaling protein Chain: A: PDB Molecule:ykui protein; PDBTitle: crystal structure of the bacillus subtilis ykui protein,2 with an eal domain, in complex with substrate c-di-gmp and3 calcium Phyre2 PDB 3pfm chain A Region: 1 - 228 Aligned: 223 Modelled: 228 Confidence: 100.0% Identity: 18% PDB header:signaling protein Chain: A: PDB Molecule:ggdef domain protein; PDBTitle: crystal structure of a eal domain of ggdef domain protein from2 pseudomonas fluorescens pf Phyre2 PDB 2r6o chain B Region: 1 - 237 Aligned: 224 Modelled: 225 Confidence: 100.0% Identity: 20% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative diguanylate cyclase/phosphodiesterase (ggdef & eal PDBTitle: crystal structure of putative diguanylate cyclase/phosphodiesterase2 from thiobacillus denitrificans Phyre2 PDB 2bas chain A domain 1 Region: 1 - 236 Aligned: 231 Modelled: 236 Confidence: 100.0% Identity: 12% Fold: TIM beta/alpha-barrel Superfamily: EAL domain-like Family: EAL domain Phyre2 PDB 3kzp chain A Region: 10 - 227 Aligned: 215 Modelled: 218 Confidence: 100.0% Identity: 14% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative diguanylate cyclase/phosphodiesterase; PDBTitle: crystal structure of putative diguanylate cyclase/phosphodiesterase2 from listaria monocytigenes Phyre2 PDB 3b2n chain A Region: 120 - 237 Aligned: 109 Modelled: 118 Confidence: 94.8% Identity: 11% PDB header:transcription Chain: A: PDB Molecule:uncharacterized protein q99uf4; PDBTitle: crystal structure of dna-binding response regulator, luxr family, from2 staphylococcus aureus Phyre2 PDB 3kht chain A Region: 120 - 236 Aligned: 109 Modelled: 117 Confidence: 94.0% Identity: 9% PDB header:signaling protein Chain: A: PDB Molecule:response regulator; PDBTitle: crystal structure of response regulator from hahella chejuensis Phyre2 PDB 1zes chain A domain 1 Region: 120 - 237 Aligned: 108 Modelled: 115 Confidence: 93.5% Identity: 9% Fold: Flavodoxin-like Superfamily: CheY-like Family: CheY-related Phyre2 PDB 1dz3 chain A Region: 120 - 237 Aligned: 110 Modelled: 113 Confidence: 93.5% Identity: 12% Fold: Flavodoxin-like Superfamily: CheY-like Family: CheY-related Phyre2 PDB 2ayx chain A Region: 120 - 237 Aligned: 107 Modelled: 118 Confidence: 92.9% Identity: 12% PDB header:transferase Chain: A: PDB Molecule:sensor kinase protein rcsc; PDBTitle: solution structure of the e.coli rcsc c-terminus (residues2 700-949) containing linker region and phosphoreceiver3 domain Phyre2 PDB 3heb chain B Region: 120 - 237 Aligned: 110 Modelled: 118 Confidence: 92.7% Identity: 9% PDB header:transcription regulator Chain: B: PDB Molecule:response regulator receiver domain protein (chey); PDBTitle: crystal structure of response regulator receiver domain from2 rhodospirillum rubrum Phyre2 PDB 1hey chain A Region: 129 - 237 Aligned: 101 Modelled: 109 Confidence: 92.2% Identity: 9% Fold: Flavodoxin-like Superfamily: CheY-like Family: CheY-related Phyre2 PDB 1p6q chain A Region: 120 - 237 Aligned: 110 Modelled: 115 Confidence: 92.2% Identity: 12% Fold: Flavodoxin-like Superfamily: CheY-like Family: CheY-related Phyre2 PDB 1w25 chain A domain 1 Region: 120 - 237 Aligned: 108 Modelled: 118 Confidence: 91.8% Identity: 11% Fold: Flavodoxin-like Superfamily: CheY-like Family: CheY-related Phyre2 PDB 1mvo chain A Region: 120 - 237 Aligned: 107 Modelled: 118 Confidence: 91.7% Identity: 9% Fold: Flavodoxin-like Superfamily: CheY-like Family: CheY-related Phyre2 1 c3hvbB_ 2 c3s83A_ 3 c3hv9A_ 4 c3pjwA_ 5 c3gfzB_ 6 c2w27A_ 7 c3pfmA_ 8 c2r6oB_ 9 d2basa1 10 c3kzpA_ 11 c3b2nA_ 12 c3khtA_ 13 d1zesa1 14 d1dz3a_ 15 c2ayxA_ 16 c3hebB_ 17 d1heya_ 18 d1p6qa_ 19 d1w25a1 20 d1mvoa_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3hvbB_ 100.0 12 PDB header:hydrolase Chain: B: PDB Molecule:protein fimx; PDBTitle: crystal structure of the dual-domain ggdef-eal module of2 fimx from pseudomonas aeruginosa 2 c3s83A_ 100.0 14 PDB header:signaling protein Chain: A: PDB Molecule:ggdef family protein; PDBTitle: crystal structure of eal domain from caulobacter crescentus cb15 3 c3hv9A_ 100.0 12 PDB header:hydrolase Chain: A: PDB Molecule:protein fimx; PDBTitle: crystal structure of fimx eal domain from pseudomonas aeruginosa 4 c3pjwA_ 100.0 17 PDB header:lyase Chain: A: PDB Molecule:cyclic dimeric gmp binding protein; PDBTitle: structure of pseudomonas fluorescence lapd ggdef-eal dual domain, i23 5 c3gfzB_ 100.0 12 PDB header:hydrolase, signaling protein Chain: B: PDB Molecule:klebsiella pneumoniae blrp1; PDBTitle: klebsiella pneumoniae blrp1 ph 6 manganese/cy-digmp complex 6 c2w27A_ 100.0 13 PDB header:signaling protein Chain: A: PDB Molecule:ykui protein; PDBTitle: crystal structure of the bacillus subtilis ykui protein,2 with an eal domain, in complex with substrate c-di-gmp and3 calcium 7 c3pfmA_ 100.0 18 PDB header:signaling protein Chain: A: PDB Molecule:ggdef domain protein; PDBTitle: crystal structure of a eal domain of ggdef domain protein from2 pseudomonas fluorescens pf 8 c2r6oB_ 100.0 20 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative diguanylate cyclase/phosphodiesterase (ggdef & eal PDBTitle: crystal structure of putative diguanylate cyclase/phosphodiesterase2 from thiobacillus denitrificans 9 d2basa1 100.0 12 Fold:TIM beta/alpha-barrel Superfamily:EAL domain-like Family:EAL domain 10 c3kzpA_ 100.0 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative diguanylate cyclase/phosphodiesterase; PDBTitle: crystal structure of putative diguanylate cyclase/phosphodiesterase2 from listaria monocytigenes 11 c3b2nA_ 94.8 11 PDB header:transcription Chain: A: PDB Molecule:uncharacterized protein q99uf4; PDBTitle: crystal structure of dna-binding response regulator, luxr family, from2 staphylococcus aureus 12 c3khtA_ 94.0 9 PDB header:signaling protein Chain: A: PDB Molecule:response regulator; PDBTitle: crystal structure of response regulator from hahella chejuensis 13 d1zesa1 93.5 9 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 14 d1dz3a_ 93.5 12 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 15 c2ayxA_ 92.9 12 PDB header:transferase Chain: A: PDB Molecule:sensor kinase protein rcsc; PDBTitle: solution structure of the e.coli rcsc c-terminus (residues2 700-949) containing linker region and phosphoreceiver3 domain 16 c3hebB_ 92.7 9 PDB header:transcription regulator Chain: B: PDB Molecule:response regulator receiver domain protein (chey); PDBTitle: crystal structure of response regulator receiver domain from2 rhodospirillum rubrum 17 d1heya_ 92.2 9 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 18 d1p6qa_ 92.2 12 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 19 d1w25a1 91.8 11 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 20 d1mvoa_ 91.7 9 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 21 d1u0sy_ not modelled 91.6 10 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 22 d1qkka_ not modelled 91.5 9 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 23 d1jbea_ not modelled 91.3 9 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 24 c2pz0B_ not modelled 90.8 8 PDB header:hydrolase Chain: B: PDB Molecule:glycerophosphoryl diester phosphodiesterase; PDBTitle: crystal structure of glycerophosphodiester phosphodiesterase (gdpd)2 from t. tengcongensis 25 c3cz5B_ not modelled 90.6 6 PDB header:transcription regulator Chain: B: PDB Molecule:two-component response regulator, luxr family; PDBTitle: crystal structure of two-component response regulator, luxr family,2 from aurantimonas sp. si85-9a1 26 c3gt7A_ not modelled 90.3 7 PDB header:hydrolase Chain: A: PDB Molecule:sensor protein; PDBTitle: crystal structure of signal receiver domain of signal2 transduction histidine kinase from syntrophus3 aciditrophicus 27 c2zayA_ not modelled 90.3 12 PDB header:signaling protein Chain: A: PDB Molecule:response regulator receiver protein; PDBTitle: crystal structure of response regulator from desulfuromonas2 acetoxidans 28 d1krwa_ not modelled 90.1 12 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 29 d2a9pa1 not modelled 90.0 7 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 30 c2qr3A_ not modelled 89.5 9 PDB header:transcription Chain: A: PDB Molecule:two-component system response regulator; PDBTitle: crystal structure of the n-terminal signal receiver domain of two-2 component system response regulator from bacteroides fragilis 31 d2pl1a1 not modelled 89.0 7 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 32 d2r25b1 not modelled 88.5 9 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 33 c3nhzA_ not modelled 88.3 10 PDB header:dna binding protein Chain: A: PDB Molecule:two component system transcriptional regulator mtra; PDBTitle: structure of n-terminal domain of mtra 34 d1a04a2 not modelled 88.2 8 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 35 c3gl9B_ not modelled 87.9 6 PDB header:signaling protein Chain: B: PDB Molecule:response regulator; PDBTitle: the structure of a histidine kinase-response regulator2 complex sheds light into two-component signaling and3 reveals a novel cis autophosphorylation mechanism 36 c2yxbA_ not modelled 87.7 11 PDB header:isomerase Chain: A: PDB Molecule:coenzyme b12-dependent mutase; PDBTitle: crystal structure of the methylmalonyl-coa mutase alpha-subunit from2 aeropyrum pernix 37 c3f6cB_ not modelled 87.6 14 PDB header:dna binding protein Chain: B: PDB Molecule:positive transcription regulator evga; PDBTitle: crystal structure of n-terminal domain of positive transcription2 regulator evga from escherichia coli 38 c2jk1A_ not modelled 87.5 15 PDB header:dna-binding Chain: A: PDB Molecule:hydrogenase transcriptional regulatory protein hupr1; PDBTitle: crystal structure of the wild-type hupr receiver domain 39 d1h5ya_ not modelled 87.5 16 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Histidine biosynthesis enzymes 40 c2qvgA_ not modelled 87.4 12 PDB header:transferase Chain: A: PDB Molecule:two component response regulator; PDBTitle: the crystal structure of a two-component response regulator2 from legionella pneumophila 41 d2ayxa1 not modelled 87.2 12 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 42 c2zwmA_ not modelled 87.0 10 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulatory protein yycf; PDBTitle: crystal structure of yycf receiver domain from bacillus2 subtilis 43 c3luaA_ not modelled 86.7 12 PDB header:transcription regulator Chain: A: PDB Molecule:response regulator receiver protein; PDBTitle: crystal structure of a signal receiver domain of two component signal2 transduction (histidine kinase) from clostridium thermocellum 44 c3rqiA_ not modelled 86.5 12 PDB header:transcription Chain: A: PDB Molecule:response regulator protein; PDBTitle: crystal structure of a response regulator protein from burkholderia2 pseudomallei with a phosphorylated aspartic acid, calcium ion and3 citrate 45 d1peya_ not modelled 86.4 14 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 46 d1ka9f_ not modelled 85.0 16 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Histidine biosynthesis enzymes 47 c3cg0A_ not modelled 84.7 13 PDB header:lyase Chain: A: PDB Molecule:response regulator receiver modulated diguanylate cyclase PDBTitle: crystal structure of signal receiver domain of modulated diguanylate2 cyclase from desulfovibrio desulfuricans g20, an example of alternate3 folding 48 c3m6mF_ not modelled 84.6 8 PDB header:lyase/transferase Chain: F: PDB Molecule:sensory/regulatory protein rpfc; PDBTitle: crystal structure of rpff complexed with rec domain of rpfc 49 c3lteH_ not modelled 84.5 8 PDB header:transcription Chain: H: PDB Molecule:response regulator; PDBTitle: crystal structure of response regulator (signal receiver domain) from2 bermanella marisrubri 50 c3cnbC_ not modelled 84.5 10 PDB header:dna binding protein Chain: C: PDB Molecule:dna-binding response regulator, merr family; PDBTitle: crystal structure of signal receiver domain of dna binding response2 regulator protein (merr) from colwellia psychrerythraea 34h 51 d1k68a_ not modelled 84.3 8 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 52 d1k66a_ not modelled 84.2 10 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 53 c3t6kB_ not modelled 84.0 7 PDB header:signaling protein Chain: B: PDB Molecule:response regulator receiver; PDBTitle: crystal structure of a hypothetical response regulator (caur_3799)2 from chloroflexus aurantiacus j-10-fl at 1.86 a resolution 54 d1yioa2 not modelled 83.6 7 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 55 c3eulB_ not modelled 83.6 14 PDB header:transcription Chain: B: PDB Molecule:possible nitrate/nitrite response transcriptional PDBTitle: structure of the signal receiver domain of the putative2 response regulator narl from mycobacterium tuberculosis 56 d1s8na_ not modelled 83.3 9 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 57 c3i42A_ not modelled 83.1 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:response regulator receiver domain protein (chey- PDBTitle: structure of response regulator receiver domain (chey-like)2 from methylobacillus flagellatus 58 d1i3ca_ not modelled 82.2 10 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 59 c2nt3A_ not modelled 82.2 8 PDB header:signaling protein Chain: A: PDB Molecule:response regulator homolog; PDBTitle: receiver domain from myxococcus xanthus social motility protein frzs2 (y102a mutant) 60 c3cu5B_ not modelled 82.1 11 PDB header:transcription regulator Chain: B: PDB Molecule:two component transcriptional regulator, arac family; PDBTitle: crystal structure of a two component transcriptional regulator arac2 from clostridium phytofermentans isdg 61 c1w25B_ not modelled 82.1 11 PDB header:signaling protein Chain: B: PDB Molecule:stalked-cell differentiation controlling protein; PDBTitle: response regulator pled in complex with c-digmp 62 c3eodA_ not modelled 81.7 13 PDB header:signaling protein Chain: A: PDB Molecule:protein hnr; PDBTitle: crystal structure of n-terminal domain of e. coli rssb 63 d1xhfa1 not modelled 81.4 9 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 64 d1xi3a_ not modelled 81.3 5 Fold:TIM beta/alpha-barrel Superfamily:Thiamin phosphate synthase Family:Thiamin phosphate synthase 65 d1kgsa2 not modelled 81.2 8 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 66 c3hv2B_ not modelled 81.1 11 PDB header:signaling protein Chain: B: PDB Molecule:response regulator/hd domain protein; PDBTitle: crystal structure of signal receiver domain of hd domain-2 containing protein from pseudomonas fluorescens pf-5 67 d1ys7a2 not modelled 80.4 7 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 68 c2qxyB_ not modelled 80.4 6 PDB header:transcription Chain: B: PDB Molecule:response regulator; PDBTitle: crystal structure of a response regulator from thermotoga2 maritima 69 c3c97A_ not modelled 80.0 13 PDB header:signaling protein, transferase Chain: A: PDB Molecule:signal transduction histidine kinase; PDBTitle: crystal structure of the response regulator receiver domain2 of a signal transduction histidine kinase from aspergillus3 oryzae 70 d1y0ea_ not modelled 80.0 8 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:NanE-like 71 d1ny5a1 not modelled 80.0 13 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 72 d1dbwa_ not modelled 79.5 9 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 73 c3ch0A_ not modelled 79.1 8 PDB header:hydrolase Chain: A: PDB Molecule:glycerophosphodiester phosphodiesterase; PDBTitle: crystal structure of glycerophosphoryl diester phosphodiesterase2 (yp_677622.1) from cytophaga hutchinsonii atcc 33406 at 1.50 a3 resolution 74 c2rjnA_ not modelled 78.7 12 PDB header:hydrolase Chain: A: PDB Molecule:response regulator receiver:metal-dependent PDBTitle: crystal structure of an uncharacterized protein q2bku2 from2 neptuniibacter caesariensis 75 c3ktoA_ not modelled 78.3 7 PDB header:transcription regulator Chain: A: PDB Molecule:response regulator receiver protein; PDBTitle: crystal structure of response regulator receiver protein2 from pseudoalteromonas atlantica 76 c3hdgE_ not modelled 77.9 8 PDB header:structural genomics, unknown function Chain: E: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of the n-terminal domain of an2 uncharacterized protein (ws1339) from wolinella3 succinogenes 77 c2y85D_ not modelled 77.7 18 PDB header:isomerase Chain: D: PDB Molecule:phosphoribosyl isomerase a; PDBTitle: crystal structure of mycobacterium tuberculosis phosphoribosyl2 isomerase with bound rcdrp 78 d1vd6a1 not modelled 77.6 8 Fold:TIM beta/alpha-barrel Superfamily:PLC-like phosphodiesterases Family:Glycerophosphoryl diester phosphodiesterase 79 d1mb3a_ not modelled 77.5 9 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 80 d1thfd_ not modelled 77.1 14 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Histidine biosynthesis enzymes 81 c2otdC_ not modelled 76.8 8 PDB header:hydrolase Chain: C: PDB Molecule:glycerophosphodiester phosphodiesterase; PDBTitle: the crystal structure of the glycerophosphodiester phosphodiesterase2 from shigella flexneri 2a 82 c3rlhA_ not modelled 76.7 9 PDB header:hydrolase Chain: A: PDB Molecule:sphingomyelin phosphodiesterase d lisictox-alphaia1a; PDBTitle: crystal structure of a class ii phospholipase d from loxosceles2 intermedia venom 83 c2p76H_ not modelled 76.2 0 PDB header:hydrolase Chain: H: PDB Molecule:glycerophosphoryl diester phosphodiesterase; PDBTitle: crystal structure of a glycerophosphodiester phosphodiesterase from2 staphylococcus aureus 84 c3crnA_ not modelled 76.1 7 PDB header:signaling protein Chain: A: PDB Molecule:response regulator receiver domain protein, chey-like; PDBTitle: crystal structure of response regulator receiver domain protein (chey-2 like) from methanospirillum hungatei jf-1 85 c2qr6A_ not modelled 75.9 15 PDB header:oxidoreductase Chain: A: PDB Molecule:imp dehydrogenase/gmp reductase; PDBTitle: crystal structure of imp dehydrogenase/gmp reductase-like protein2 (np_599840.1) from corynebacterium glutamicum atcc 13032 kitasato at3 1.50 a resolution 86 c1yadD_ not modelled 75.9 11 PDB header:transcription Chain: D: PDB Molecule:regulatory protein teni; PDBTitle: structure of teni from bacillus subtilis 87 d1znna1 not modelled 75.6 15 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:PdxS-like 88 c3q58A_ not modelled 75.5 14 PDB header:isomerase Chain: A: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase; PDBTitle: structure of n-acetylmannosamine-6-phosphate epimerase from salmonella2 enterica 89 c3l12A_ not modelled 75.3 5 PDB header:hydrolase Chain: A: PDB Molecule:putative glycerophosphoryl diester phosphodiesterase; PDBTitle: crystal structure of putative glycerophosphoryl diester2 phosphodiesterase (yp_165505.1) from silicibacter pomeroyi dss-3 at3 1.60 a resolution 90 c2h6rG_ not modelled 74.9 14 PDB header:isomerase Chain: G: PDB Molecule:triosephosphate isomerase; PDBTitle: crystal structure of triosephosphate isomerase (tim) from2 methanocaldococcus jannaschii 91 c3qvqB_ not modelled 74.8 8 PDB header:hydrolase Chain: B: PDB Molecule:phosphodiesterase olei02445; PDBTitle: the structure of an oleispira antarctica phosphodiesterase olei024452 in complex with the product sn-glycerol-3-phosphate 92 d1piia2 not modelled 74.3 8 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 93 d1fmfa_ not modelled 74.3 10 Fold:Flavodoxin-like Superfamily:Cobalamin (vitamin B12)-binding domain Family:Cobalamin (vitamin B12)-binding domain 94 c1znnF_ not modelled 72.9 15 PDB header:biosynthetic protein Chain: F: PDB Molecule:plp synthase; PDBTitle: structure of the synthase subunit of plp synthase 95 c3cfyA_ not modelled 72.7 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative luxo repressor protein; PDBTitle: crystal structure of signal receiver domain of putative luxo2 repressor protein from vibrio parahaemolyticus 96 c3ffsC_ not modelled 72.4 16 PDB header:oxidoreductase Chain: C: PDB Molecule:inosine-5-monophosphate dehydrogenase; PDBTitle: the crystal structure of cryptosporidium parvum inosine-5'-2 monophosphate dehydrogenase 97 d1zgza1 not modelled 72.3 10 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 98 c2jrlA_ not modelled 71.9 13 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator (ntrc family); PDBTitle: solution structure of the beryllofluoride-activated ntrc4 receiver2 domain dimer 99 d1zh2a1 not modelled 71.5 11 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 100 c3mmnA_ not modelled 71.2 15 PDB header:transferase Chain: A: PDB Molecule:histidine kinase homolog; PDBTitle: crystal structure of the receiver domain of the histidine kinase cki12 from arabidopsis thaliana complexed with mg2+ 101 c2qzjC_ not modelled 70.9 7 PDB header:transcription Chain: C: PDB Molecule:two-component response regulator; PDBTitle: crystal structure of a two-component response regulator from2 clostridium difficile 102 c3igsB_ not modelled 70.7 14 PDB header:isomerase Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2; PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase 103 c3uj2C_ not modelled 70.2 7 PDB header:lyase Chain: C: PDB Molecule:enolase 1; PDBTitle: crystal structure of an enolase from anaerostipes caccae (efi target2 efi-502054) with bound mg and sulfate 104 c3ilhA_ not modelled 70.0 9 PDB header:transcription regulator Chain: A: PDB Molecule:two component response regulator; PDBTitle: crystal structure of two component response regulator from cytophaga2 hutchinsonii 105 c3grcD_ not modelled 69.7 12 PDB header:transferase Chain: D: PDB Molecule:sensor protein, kinase; PDBTitle: crystal structure of a sensor protein from polaromonas sp.2 js666 106 c2v82A_ not modelled 69.6 16 PDB header:lyase Chain: A: PDB Molecule:2-dehydro-3-deoxy-6-phosphogalactonate aldolase; PDBTitle: kdpgal complexed to kdpgal 107 d1o1za_ not modelled 69.3 9 Fold:TIM beta/alpha-barrel Superfamily:PLC-like phosphodiesterases Family:Glycerophosphoryl diester phosphodiesterase 108 d1dcfa_ not modelled 69.3 12 Fold:Flavodoxin-like Superfamily:CheY-like Family:Receiver domain of the ethylene receptor 109 d1a53a_ not modelled 68.3 11 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 110 d2al1a1 not modelled 66.6 12 Fold:TIM beta/alpha-barrel Superfamily:Enolase C-terminal domain-like Family:Enolase 111 c1piiA_ not modelled 66.5 8 PDB header:bifunctional(isomerase and synthase) Chain: A: PDB Molecule:n-(5'phosphoribosyl)anthranilate isomerase; PDBTitle: three-dimensional structure of the bifunctional enzyme2 phosphoribosylanthranilate isomerase:3 indoleglycerolphosphate synthase from escherichia coli4 refined at 2.0 angstroms resolution 112 c3t8yA_ not modelled 66.1 8 PDB header:hydrolase Chain: A: PDB Molecule:chemotaxis response regulator protein-glutamate PDBTitle: crystal structure of the response regulator domain of thermotoga2 maritima cheb 113 c3hdvB_ not modelled 66.1 13 PDB header:transcription regulator Chain: B: PDB Molecule:response regulator; PDBTitle: crystal structure of response regulator receiver protein from2 pseudomonas putida 114 d1xm3a_ not modelled 66.1 12 Fold:TIM beta/alpha-barrel Superfamily:ThiG-like Family:ThiG-like 115 c3gr7A_ not modelled 66.0 8 PDB header:oxidoreductase Chain: A: PDB Molecule:nadph dehydrogenase; PDBTitle: structure of oye from geobacillus kaustophilus, hexagonal2 crystal form 116 c3h1gA_ not modelled 65.3 6 PDB header:signaling protein Chain: A: PDB Molecule:chemotaxis protein chey homolog; PDBTitle: crystal structure of chey mutant t84a of helicobacter pylori 117 c3ktsA_ not modelled 65.2 22 PDB header:transcriptional regulator Chain: A: PDB Molecule:glycerol uptake operon antiterminator regulatory protein; PDBTitle: crystal structure of glycerol uptake operon antiterminator regulatory2 protein from listeria monocytogenes str. 4b f2365 118 c2qv0A_ not modelled 65.1 10 PDB header:transcription Chain: A: PDB Molecule:protein mrke; PDBTitle: crystal structure of the response regulatory domain of2 protein mrke from klebsiella pneumoniae 119 c3hzhA_ not modelled 65.0 3 PDB header:signaling protein Chain: A: PDB Molecule:chemotaxis response regulator (chey-3); PDBTitle: crystal structure of the chex-chey-bef3-mg+2 complex from2 borrelia burgdorferi 120 c3kruC_ not modelled 64.3 10 PDB header:oxidoreductase Chain: C: PDB Molecule:nadh:flavin oxidoreductase/nadh oxidase; PDBTitle: crystal structure of the thermostable old yellow enzyme from2 thermoanaerobacter pseudethanolicus e39

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0