Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	G	Q	V	L	P	L	V	T	R	Q	G	D	R	I	A	I	V	S	G	L	R	T	P	F	A	R	Q	A	T	A	F	H	G	I	P	A	V	D	L	G	K	M	V	V	G	E	L	L	A	R	S	E	I	P	A	E	V	I	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Q	L	V	F	G	Q	V	V	Q	M	P	E	A	P	N	I	A	R	E	I	V	L	G	T	G	M	N	V	H	T	D	A	Y	S	V	S	R	A	C	A	T	S	F	Q	A	V	A	N	V	A	E	S	L	M	A	G	T	I	R	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	I	A	G	G	A	D	S	S	S	V	L	P	I	G	V	S	K	K	L	A	R	V	L	V	D	V	N	K	A	R	T	M	S	Q	R	L	K	L	F	S	R	L	R	L	R	D	L	M	P	V	P	P	A	V	A	E	Y	S	T
Secondary structure
SS confidence
Disorder																?	?		?	?	?	?	?	?	?		?													?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		G	L	R	M	G	D	T	A	E	Q	M	A	K	T	Y	G	I	T	R	E	Q	Q	D	A	L	A	H	R	S	H	Q	R	A	A	Q	A	W	S	D	G	K	L	K	E	E	V	M	T	A	F	I	P	P	Y	K	Q	P	L	V	E
Secondary structure
SS confidence
Disorder																																								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		D	N	N	I	R	G	N	S	S	L	A	D	Y	A	K	L	R	P	A	F	D	R	K	H	G	T	V	T	A	A	N	S	T	P	L	T	D	G	A	A	A	V	I	L	M	T	E	S	R	A	K	E	L	G	L	V	P	L	G	Y
Secondary structure
SS confidence
Disorder															?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		L	R	S	Y	A	F	T	A	I	D	V	W	Q	D	M	L	L	G	P	A	W	S	T	P	L	A	L	E	R	A	G	L	T	M	S	D	L	T	L	I	D	M	H	E	A	F	A	A	Q	T	L	A	N	I	Q	L	L	G	S	E
Secondary structure
SS confidence
Disorder													?			?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		R	F	A	R	E	A	L	G	R	A	H	A	T	G	E	V	D	D	S	K	F	N	V	L	G	G	S	I	A	Y	G	H	P	F	A	A	T	G	A	R	M	I	T	Q	T	L	H	E	L	R	R	R	G	G	G	F	G	L	V	T
Secondary structure
SS confidence
Disorder														?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.
Sequence		A	C	A	A	G	G	L	G	A	A	M	V	L	E	A	E
Secondary structure
SS confidence
Disorder																?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1ulq chain D Region: 14 - 435 Aligned: 394 Modelled: 407 Confidence: 100.0% Identity: 39% PDB header:transferase Chain: D: PDB Molecule:putative acetyl-coa acetyltransferase; PDBTitle: crystal structure of tt0182 from thermus thermophilus hb8 Phyre2 PDB 3ss6 chain B Region: 11 - 435 Aligned: 388 Modelled: 391 Confidence: 100.0% Identity: 31% PDB header:transferase Chain: B: PDB Molecule:acetyl-coa acetyltransferase; PDBTitle: crystal structure of the bacillus anthracis acetyl-coa2 acetyltransferase Phyre2 PDB 1afw chain B Region: 5 - 436 Aligned: 387 Modelled: 389 Confidence: 100.0% Identity: 30% PDB header:thiolase Chain: B: PDB Molecule:3-ketoacetyl-coa thiolase; PDBTitle: the 1.8 angstrom crystal structure of the dimeric2 peroxisomal thiolase of saccharomyces cerevisiae Phyre2 PDB 2vu2 chain D Region: 15 - 435 Aligned: 385 Modelled: 387 Confidence: 100.0% Identity: 38% PDB header:transferase Chain: D: PDB Molecule:acetyl-coa acetyltransferase; PDBTitle: biosynthetic thiolase from z. ramigera. complex with s-2 pantetheine-11-pivalate. Phyre2 PDB 2d3t chain C Region: 11 - 435 Aligned: 381 Modelled: 382 Confidence: 100.0% Identity: 37% PDB header:lyase, oxidoreductase/transferase Chain: C: PDB Molecule:3-ketoacyl-coa thiolase; PDBTitle: fatty acid beta-oxidation multienzyme complex from2 pseudomonas fragi, form v Phyre2 PDB 2iby chain D Region: 9 - 435 Aligned: 388 Modelled: 388 Confidence: 100.0% Identity: 31% PDB header:transferase Chain: D: PDB Molecule:acetyl-coa acetyltransferase; PDBTitle: crystallographic and kinetic studies of human mitochondrial2 acetoacetyl-coa thiolase (t2): the importance of potassium and3 chloride for its structure and function Phyre2 PDB 1wl5 chain A Region: 12 - 436 Aligned: 389 Modelled: 391 Confidence: 100.0% Identity: 32% PDB header:transferase Chain: A: PDB Molecule:acetyl-coenzyme a acetyltransferase 2; PDBTitle: human cytosolic acetoacetyl-coa thiolase Phyre2 PDB 2wua chain A Region: 12 - 435 Aligned: 378 Modelled: 380 Confidence: 100.0% Identity: 35% PDB header:transferase Chain: A: PDB Molecule:acetoacetyl coa thiolase; PDBTitle: structure of the peroxisomal 3-ketoacyl-coa thiolase from2 sunflower Phyre2 PDB 2iik chain A Region: 10 - 435 Aligned: 376 Modelled: 378 Confidence: 100.0% Identity: 36% PDB header:transferase Chain: A: PDB Molecule:3-ketoacyl-coa thiolase, peroxisomal; PDBTitle: crystal structure of human peroxisomal acetyl-coa acyl transferase 12 (acaa1) Phyre2 PDB 2c7y chain B Region: 11 - 435 Aligned: 372 Modelled: 372 Confidence: 100.0% Identity: 38% PDB header:transferase Chain: B: PDB Molecule:3-ketoacyl-coa thiolase 2; PDBTitle: plant enzyme Phyre2 PDB 3goa chain A Region: 13 - 435 Aligned: 372 Modelled: 371 Confidence: 100.0% Identity: 37% PDB header:transferase Chain: A: PDB Molecule:3-ketoacyl-coa thiolase; PDBTitle: crystal structure of the salmonella typhimurium fada 3-2 ketoacyl-coa thiolase Phyre2 PDB 3svk chain B Region: 13 - 435 Aligned: 349 Modelled: 349 Confidence: 100.0% Identity: 34% PDB header:transferase Chain: B: PDB Molecule:acetyl-coa acetyltransferase; PDBTitle: crystal structure of acetyl-coa acetyltransferase from mycobacterium2 avium Phyre2 PDB 1afw chain A domain 1 Region: 7 - 292 Aligned: 258 Modelled: 262 Confidence: 100.0% Identity: 26% Fold: Thiolase-like Superfamily: Thiolase-like Family: Thiolase-related Phyre2 PDB 1m3k chain A domain 1 Region: 11 - 294 Aligned: 266 Modelled: 267 Confidence: 100.0% Identity: 33% Fold: Thiolase-like Superfamily: Thiolase-like Family: Thiolase-related Phyre2 PDB 1ulq chain A domain 1 Region: 14 - 295 Aligned: 270 Modelled: 282 Confidence: 100.0% Identity: 36% Fold: Thiolase-like Superfamily: Thiolase-like Family: Thiolase-related Phyre2 PDB 1wdk chain C domain 1 Region: 11 - 293 Aligned: 254 Modelled: 254 Confidence: 100.0% Identity: 33% Fold: Thiolase-like Superfamily: Thiolase-like Family: Thiolase-related Phyre2 PDB 1ulq chain A domain 2 Region: 296 - 435 Aligned: 124 Modelled: 125 Confidence: 100.0% Identity: 46% Fold: Thiolase-like Superfamily: Thiolase-like Family: Thiolase-related Phyre2 PDB 1wdk chain C domain 2 Region: 294 - 435 Aligned: 127 Modelled: 128 Confidence: 100.0% Identity: 45% Fold: Thiolase-like Superfamily: Thiolase-like Family: Thiolase-related Phyre2 PDB 1m3k chain A domain 2 Region: 295 - 435 Aligned: 123 Modelled: 124 Confidence: 100.0% Identity: 46% Fold: Thiolase-like Superfamily: Thiolase-like Family: Thiolase-related Phyre2 PDB 1afw chain A domain 2 Region: 293 - 436 Aligned: 124 Modelled: 125 Confidence: 100.0% Identity: 40% Fold: Thiolase-like Superfamily: Thiolase-like Family: Thiolase-related Phyre2 1 c1ulqD_ 2 c3ss6B_ 3 c1afwB_ 4 c2vu2D_ 5 c2d3tC_ 6 c2ibyD_ 7 c1wl5A_ 8 c2wuaA_ 9 c2iikA_ 10 c2c7yB_ 11 c3goaA_ 12 c3svkB_ 13 d1afwa1 14 d1m3ka1 15 d1ulqa1 16 d1wdkc1 17 d1ulqa2 18 d1wdkc2 19 d1m3ka2 20 d1afwa2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1ulqD_ 100.0 39 PDB header:transferase Chain: D: PDB Molecule:putative acetyl-coa acetyltransferase; PDBTitle: crystal structure of tt0182 from thermus thermophilus hb8 2 c3ss6B_ 100.0 31 PDB header:transferase Chain: B: PDB Molecule:acetyl-coa acetyltransferase; PDBTitle: crystal structure of the bacillus anthracis acetyl-coa2 acetyltransferase 3 c1afwB_ 100.0 30 PDB header:thiolase Chain: B: PDB Molecule:3-ketoacetyl-coa thiolase; PDBTitle: the 1.8 angstrom crystal structure of the dimeric2 peroxisomal thiolase of saccharomyces cerevisiae 4 c2vu2D_ 100.0 38 PDB header:transferase Chain: D: PDB Molecule:acetyl-coa acetyltransferase; PDBTitle: biosynthetic thiolase from z. ramigera. complex with s-2 pantetheine-11-pivalate. 5 c2d3tC_ 100.0 37 PDB header:lyase, oxidoreductase/transferase Chain: C: PDB Molecule:3-ketoacyl-coa thiolase; PDBTitle: fatty acid beta-oxidation multienzyme complex from2 pseudomonas fragi, form v 6 c2ibyD_ 100.0 31 PDB header:transferase Chain: D: PDB Molecule:acetyl-coa acetyltransferase; PDBTitle: crystallographic and kinetic studies of human mitochondrial2 acetoacetyl-coa thiolase (t2): the importance of potassium and3 chloride for its structure and function 7 c1wl5A_ 100.0 32 PDB header:transferase Chain: A: PDB Molecule:acetyl-coenzyme a acetyltransferase 2; PDBTitle: human cytosolic acetoacetyl-coa thiolase 8 c2wuaA_ 100.0 35 PDB header:transferase Chain: A: PDB Molecule:acetoacetyl coa thiolase; PDBTitle: structure of the peroxisomal 3-ketoacyl-coa thiolase from2 sunflower 9 c2iikA_ 100.0 36 PDB header:transferase Chain: A: PDB Molecule:3-ketoacyl-coa thiolase, peroxisomal; PDBTitle: crystal structure of human peroxisomal acetyl-coa acyl transferase 12 (acaa1) 10 c2c7yB_ 100.0 38 PDB header:transferase Chain: B: PDB Molecule:3-ketoacyl-coa thiolase 2; PDBTitle: plant enzyme 11 c3goaA_ 100.0 37 PDB header:transferase Chain: A: PDB Molecule:3-ketoacyl-coa thiolase; PDBTitle: crystal structure of the salmonella typhimurium fada 3-2 ketoacyl-coa thiolase 12 c3svkB_ 100.0 34 PDB header:transferase Chain: B: PDB Molecule:acetyl-coa acetyltransferase; PDBTitle: crystal structure of acetyl-coa acetyltransferase from mycobacterium2 avium 13 d1afwa1 100.0 26 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 14 d1m3ka1 100.0 33 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 15 d1ulqa1 100.0 36 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 16 d1wdkc1 100.0 33 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 17 d1ulqa2 100.0 46 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 18 d1wdkc2 100.0 45 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 19 d1m3ka2 100.0 46 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 20 d1afwa2 100.0 40 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 21 c1e5mA_ not modelled 100.0 23 PDB header:condensing enzyme Chain: A: PDB Molecule:beta ketoacyl acyl carrier protein synthase ii; PDBTitle: beta ketoacyl acyl carrier protein synthase ii (kasii) from2 synechocystis sp. 22 c2gfvA_ not modelled 100.0 23 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 2; PDBTitle: structure of e. coli fabf (kasii) c163q mutant 23 c1tqyC_ not modelled 100.0 24 PDB header:transferase Chain: C: PDB Molecule:beta-ketoacyl synthase/acyl transferase; PDBTitle: the actinorhodin ketosynthase/chain length factor 24 c1oxhD_ not modelled 100.0 20 PDB header:transferase Chain: D: PDB Molecule:beta ketoacyl-acyl carrier protein synthase; PDBTitle: the crystal structure of beta-ketoacyl-[acyl carrier2 protein] synthase ii from streptococcus pneumoniae,3 triclinic form 25 c2ix4B_ not modelled 100.0 23 PDB header:transferase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase; PDBTitle: arabidopsis thaliana mitochondrial beta-ketoacyl acp2 synthase hexanoic acid complex 26 c2gqdB_ not modelled 100.0 20 PDB header:transferase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 2; PDBTitle: the crystal structure of b-ketoacyl-acp synthase ii (fabf)2 from staphylococcus aureus 27 c2vz8B_ not modelled 100.0 19 PDB header:transferase Chain: B: PDB Molecule:fatty acid synthase; PDBTitle: crystal structure of mammalian fatty acid synthase 28 c2iwyB_ not modelled 100.0 25 PDB header:transferase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase; PDBTitle: human mitochondrial beta-ketoacyl acp synthase 29 c3e60A_ not modelled 100.0 26 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein ] synthase ii; PDBTitle: crystal structure of 3-oxoacyl-(acyl carrier protein)2 synthase ii from bartonella henselae 30 c2qo3A_ not modelled 100.0 23 PDB header:transferase Chain: A: PDB Molecule:eryaii erythromycin polyketide synthase modules 3 and 4; PDBTitle: crystal structure of [ks3][at3] didomain from module 3 of 6-2 deoxyerthronolide b synthase 31 c3hhdC_ not modelled 100.0 20 PDB header:transferase, hydrolase Chain: C: PDB Molecule:fatty acid synthase; PDBTitle: structure of the human fatty acid synthase ks-mat didomain2 as a framework for inhibitor design. 32 c3o04A_ not modelled 100.0 21 PDB header:transferase Chain: A: PDB Molecule:beta-keto-acyl carrier protein synthase ii; PDBTitle: crystal structure of the beta-keto-acyl carrier protein synthase ii2 (lmo2201) from listeria monocytogenes 33 c2gp6B_ not modelled 100.0 23 PDB header:transferase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 2; PDBTitle: x-ray crystal structure of mycobacterium tuberculosis beta-2 ketoacyl acyl carrier protein synthase ii (mtkasb) 34 c1j3nB_ not modelled 100.0 24 PDB header:transferase Chain: B: PDB Molecule:3-oxoacyl-(acyl-carrier protein) synthase ii; PDBTitle: crystal structure of 3-oxoacyl-(acyl-carrier protein)2 synthase ii from thermus thermophilus hb8 35 c2buiC_ not modelled 100.0 21 PDB header:synthase Chain: C: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase i; PDBTitle: e.coli beta-ketoacyl (acyl carrier protein) synthase i in2 complex with octanoic acid, 120k 36 c2hg4A_ not modelled 100.0 22 PDB header:transferase Chain: A: PDB Molecule:6-deoxyerythronolide b synthase; PDBTitle: structure of the ketosynthase-acyltransferase didomain of module 52 from debs. 37 c3lrfA_ not modelled 100.0 22 PDB header:transferase Chain: A: PDB Molecule:beta-ketoacyl synthase; PDBTitle: crystal structure of beta-ketoacyl synthase from brucella2 melitensis 38 c1tqyD_ not modelled 100.0 22 PDB header:transferase Chain: D: PDB Molecule:actinorhodin polyketide putative beta-ketoacyl synthase 2; PDBTitle: the actinorhodin ketosynthase/chain length factor 39 c2ebdB_ not modelled 99.9 22 PDB header:transferase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 3; PDBTitle: crystal structure of 3-oxoacyl-[acyl-carrier-protein] synthase iii2 from aquifex aeolicus vf5 40 c2wggA_ not modelled 99.9 23 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 1; PDBTitle: crystal structure of mycobacterium tuberculosis c171q kasa2 variant with bound tlm 41 c2qnxA_ not modelled 99.9 21 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 3; PDBTitle: crystal structure of the complex between the mycobacterium beta-2 ketoacyl-acyl carrier protein synthase iii (fabh) and 11-3 [(decyloxycarbonyl)dithio]-undecanoic acid 42 c3gwaA_ not modelled 99.9 21 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-(acyl-carrier-protein) synthase iii; PDBTitle: 1.6 angstrom crystal structure of 3-oxoacyl-(acyl-carrier-protein)2 synthase iii 43 c2uv8C_ not modelled 99.9 24 PDB header:transferase Chain: C: PDB Molecule:fatty acid synthase subunit alpha (fas2); PDBTitle: crystal structure of yeast fatty acid synthase with stalled2 acyl carrier protein at 3.1 angstrom resolution 44 c1mzjB_ not modelled 99.9 26 PDB header:transferase Chain: B: PDB Molecule:beta-ketoacylsynthase iii; PDBTitle: crystal structure of the priming beta-ketosynthase from the2 r1128 polyketide biosynthetic pathway 45 c2vkzC_ not modelled 99.9 25 PDB header:transferase Chain: C: PDB Molecule:fatty acid synthase subunit alpha; PDBTitle: structure of the cerulenin-inhibited fungal fatty acid2 synthase type i multienzyme complex 46 c3fk5A_ not modelled 99.9 23 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-synthase iii; PDBTitle: crystal structure of 3-oxoacyl-(acyl carrier protein)2 synthase iii, fabh (xoo4209) from xanthomonas oryzae pv.3 oryzae kacc10331 47 c1ee0A_ not modelled 99.9 18 PDB header:transferase Chain: A: PDB Molecule:2-pyrone synthase; PDBTitle: 2-pyrone synthase complexed with acetoacetyl-coa 48 c3il3A_ not modelled 99.9 19 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 3; PDBTitle: structure of haemophilus influenzae fabh 49 c3ledA_ not modelled 99.9 19 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-acyl carrier protein synthase iii; PDBTitle: crystal structure of 3-oxoacyl-(acyl carrier protein) synthase iii2 from rhodopseudomonas palustris cga009 50 c1zowB_ not modelled 99.9 27 PDB header:transferase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase iii; PDBTitle: crystal structure of s. aureus fabh, beta-ketoacyl carrier protein2 synthase iii 51 c2gyoB_ not modelled 99.9 22 PDB header:transferase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 3; PDBTitle: methanethiol-cys 112 inhibition complex of e. coli ketoacyl synthase2 iii (fabh) and coenzyme a 52 c2uv9B_ not modelled 99.9 27 PDB header:transferase Chain: B: PDB Molecule:fatty acid synthase alpha subunits; PDBTitle: crystal structure of fatty acid synthase from thermomyces2 lanuginosus at 3.1 angstrom resolution. this file contains3 the alpha subunits of the fatty acid synthase. the entire4 crystal structure consists of one heterododecameric fatty5 acid synthase and is described in remark 400 53 c2p0uB_ not modelled 99.9 22 PDB header:transferase Chain: B: PDB Molecule:stilbenecarboxylate synthase 2; PDBTitle: crystal structure of marchantia polymorpha stilbenecarboxylate2 synthase 2 (stcs2) 54 c3h76A_ not modelled 99.9 20 PDB header:transferase Chain: A: PDB Molecule:pqs biosynthetic enzyme; PDBTitle: crystal structure of pqsd, a key enzyme in pseudomonas2 aeruginosa quinolone signal biosynthesis pathway 55 c3ov3A_ not modelled 99.9 19 PDB header:transferase Chain: A: PDB Molecule:curcumin synthase; PDBTitle: g211f mutant of curcumin synthase 1 from curcuma longa 56 c1u0mA_ not modelled 99.9 23 PDB header:biosynthetic protein Chain: A: PDB Molecule:putative polyketide synthase; PDBTitle: crystal structure of 1,3,6,8-tetrahydroxynaphthalene synthase (thns)2 from streptomyces coelicolor a3(2): a bacterial type iii polyketide3 synthase (pks) provides insights into enzymatic control of reactive4 polyketide intermediates 57 c3a5qA_ not modelled 99.9 19 PDB header:transferase Chain: A: PDB Molecule:benzalacetone synthase; PDBTitle: benzalacetone synthase from rheum palmatum 58 c1xetD_ not modelled 99.9 16 PDB header:transferase Chain: D: PDB Molecule:dihydropinosylvin synthase; PDBTitle: crystal structure of stilbene synthase from pinus2 sylvestris, complexed with methylmalonyl coa 59 c2d3mA_ not modelled 99.9 19 PDB header:transferase Chain: A: PDB Molecule:pentaketide chromone synthase; PDBTitle: pentaketide chromone synthase complexed with coenzyme a 60 c1ub7A_ not modelled 99.9 28 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier protein] synthase; PDBTitle: the crystal analysis of beta-keroacyl-[acyl carrier protein] synthase2 iii (fabh)from thermus thermophilus. 61 c1cmlA_ not modelled 99.9 18 PDB header:transferase Chain: A: PDB Molecule:protein (chalcone synthase); PDBTitle: chalcone synthase from alfalfa complexed with malonyl-coa 62 d1teda_ not modelled 99.9 22 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 63 c3oitB_ not modelled 99.9 19 PDB header:transferase Chain: B: PDB Molecule:os07g0271500 protein; PDBTitle: crystal structure of curcuminoid synthase cus from oryza sativa 64 c3il5D_ not modelled 99.9 24 PDB header:transferase Chain: D: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 3; PDBTitle: structure of e. faecalis fabh in complex with 2-({4-bromo-3-2 [(diethylamino)sulfonyl]benzoyl}amino)benzoic acid 65 c3s3lB_ not modelled 99.9 21 PDB header:transferase Chain: B: PDB Molecule:cerj; PDBTitle: crystal structure of cerj from streptomyces tendae 66 c2x3eA_ not modelled 99.9 26 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 3; PDBTitle: crystal structure of 3-oxoacyl-(acyl carrier protein)2 synthase iii, fabh from pseudomonas aeruginosa pao1 67 c3aleB_ not modelled 99.8 19 PDB header:transferase Chain: B: PDB Molecule:os07g0271500 protein; PDBTitle: a type iii polyketide synthase that produces diarylheptanoid 68 c2h84A_ not modelled 99.8 23 PDB header:biosynthetic protein, transferase Chain: A: PDB Molecule:steely1; PDBTitle: crystal structure of the c-terminal type iii polyketide synthase (pks2 iii) domain of 'steely1' (a type i/iii pks hybrid from dictyostelium) 69 c3tsyA_ not modelled 99.8 21 PDB header:ligase, transferase Chain: A: PDB Molecule:fusion protein 4-coumarate--coa ligase 1, resveratrol PDBTitle: 4-coumaroyl-coa ligase::stilbene synthase fusion protein 70 c3euoB_ not modelled 99.8 15 PDB header:transferase Chain: B: PDB Molecule:type iii pentaketide synthase; PDBTitle: crystal structure of a fungal type iii polyketide synthase,2 oras 71 c3e1hA_ not modelled 99.8 16 PDB header:transferase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of a type iii polyketide synthase2 pksiiinc from neurospora crassa 72 d2ix4a1 not modelled 99.7 27 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 73 c2f9aA_ not modelled 99.7 18 PDB header:transferase Chain: A: PDB Molecule:3-hydroxy-3-methylglutaryl coenzyme a synthase 1; PDBTitle: hmg-coa synthase from brassica juncea in complex with f-244 74 d2vbaa1 not modelled 99.7 22 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 75 d1ox0a1 not modelled 99.7 20 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 76 c1x9eB_ not modelled 99.7 17 PDB header:lyase Chain: B: PDB Molecule:hmg-coa synthase; PDBTitle: crystal structure of hmg-coa synthase from enterococcus2 faecalis 77 c2p8uB_ not modelled 99.7 15 PDB header:transferase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa synthase, cytoplasmic; PDBTitle: crystal structure of human 3-hydroxy-3-methylglutaryl coa synthase i 78 d1j3na1 not modelled 99.7 24 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 79 c2v4wB_ not modelled 99.7 20 PDB header:transferase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa synthase, PDBTitle: crystal structure of human mitochondrial 3-hydroxy-3-2 methylglutaryl-coenzyme a synthase 2 (hmgcs2) 80 d1mzja1 not modelled 99.7 16 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 81 c3lehA_ not modelled 99.6 19 PDB header:transferase Chain: A: PDB Molecule:putative hydroxymethylglutaryl-coa synthase; PDBTitle: the crystal structure of smu.943c from streptococcus mutans ua159 82 c1txtB_ not modelled 99.6 16 PDB header:lyase Chain: B: PDB Molecule:3-hydroxy-3-methylglutaryl-coa synthase; PDBTitle: staphylococcus aureus 3-hydroxy-3-methylglutaryl-coa2 synthase 83 d1hnja1 not modelled 99.6 17 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 84 d2gfva1 not modelled 99.6 25 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 85 d1tqyb2 not modelled 99.6 23 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 86 d1tqya2 not modelled 99.6 25 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 87 d1u6ea1 not modelled 99.6 15 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 88 d1ub7a1 not modelled 99.5 21 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 89 d1bi5a1 not modelled 99.5 10 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 90 d1e5ma1 not modelled 99.5 24 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 91 d1ee0a1 not modelled 99.5 13 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 92 d1u0ua1 not modelled 99.5 12 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 93 d1u0ma1 not modelled 99.4 15 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 94 d1u0va1 not modelled 99.4 12 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 95 d1xpma1 not modelled 99.3 12 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 96 d1tqya1 not modelled 99.3 18 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 97 d1tqyb1 not modelled 99.2 16 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 98 c3lmaC_ not modelled 99.1 21 PDB header:membrane protein Chain: C: PDB Molecule:stage v sporulation protein ad (spovad); PDBTitle: crystal structure of the stage v sporulation protein ad2 (spovad) from bacillus licheniformis. northeast structural3 genomics consortium target bir6. 99 d1ox0a2 not modelled 98.9 18 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 100 d1e5ma2 not modelled 98.9 20 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 101 d2gfva2 not modelled 98.8 18 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 102 d1j3na2 not modelled 98.7 20 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 103 d2ix4a2 not modelled 98.7 16 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 104 d2vbaa2 not modelled 98.1 19 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 105 d1mzja2 not modelled 98.0 28 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 106 d1u0ma2 not modelled 98.0 19 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 107 d1hnja2 not modelled 97.8 22 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 108 d1u6ea2 not modelled 97.7 18 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 109 d1ub7a2 not modelled 97.5 29 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 110 d1u0ua2 not modelled 96.1 15 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 111 d1bi5a2 not modelled 95.3 17 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 112 d1ee0a2 not modelled 94.9 17 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 113 c1okjB_ not modelled 91.9 16 PDB header:hydrolase Chain: B: PDB Molecule:hypothetical protease yeaz; PDBTitle: crystal structure of the essential e. coli yeaz2 protein by mad method using the gadolinium complex3 "dotma" 114 d2a6aa1 not modelled 90.7 12 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:YeaZ-like 115 c2a6aB_ not modelled 90.7 12 PDB header:hydrolase Chain: B: PDB Molecule:hypothetical protein tm0874; PDBTitle: crystal structure of glycoprotein endopeptidase (tm0874) from2 thermotoga maritima at 2.50 a resolution 116 d1okja1 not modelled 88.2 19 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:YeaZ-like 117 c2ivoC_ not modelled 87.5 11 PDB header:hydrolase Chain: C: PDB Molecule:up1; PDBTitle: structure of up1 protein 118 c3r6mD_ not modelled 87.2 17 PDB header:hydrolase Chain: D: PDB Molecule:yeaz, resuscitation promoting factor; PDBTitle: crystal structure of vibrio parahaemolyticus yeaz 119 c3enoB_ not modelled 84.4 8 PDB header:hydrolase/unknown function Chain: B: PDB Molecule:putative o-sialoglycoprotein endopeptidase; PDBTitle: crystal structure of pyrococcus furiosus pcc1 in complex2 with thermoplasma acidophilum kae1 120 d1saza1 not modelled 74.2 20 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Acetokinase-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0