Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0A9L8
DateThu Jan 5 11:10:40 GMT 2012
Unique Job IDc4bf8aee6e9bf529

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2izzE_
Top template information
PDB header:oxidoreductase
Chain: E: PDB Molecule:pyrroline-5-carboxylate reductase 1;
PDBTitle: crystal structure of human pyrroline-5-carboxylate2 reductase
Confidence and coverage
Confidence:100.0% Coverage: 99%
266 residues ( 99% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MEKKIGFIGCGNMGKAILGGLIASGQVLPGQIWVYTPSPDKVAALHDQFGINAAESAQEV
Secondary structure 

















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Disorder  ???




















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   .........70.........80.........90.........100.........110.........120
Sequence  AQIADIIFAAVKPGIMIKVLSEITSSLNKDSLVVSIAAGVTLDQLARALGHDRKIIRAMP
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   .........130.........140.........150.........160.........170.........180
Sequence  NTPALVNAGMTSVTPNALVTPEDTADVLNIFRCFGEAEVIAEPMIHPVVGVSGSSPAYVF
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Disorder 
?

??





















































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   .........190.........200.........210.........220.........230.........240
Sequence  MFIEAMADAAVLGGMPRAQAYKFAAQAVMGSAKMVLETGEHPGALKDMVCSPGGTTIEAV
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   .........250.........260.........
Sequence  RVLEEKGFRAAVIEAMTKCMEKSEKLSKS
Secondary structure 



SS confidence 




























Disorder 

























???
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2izz chain E

3D model

Region: 1 - 268
Aligned: 266
Modelled: 268
Confidence: 100.0%
Identity: 37%
PDB header:oxidoreductase
Chain: E: PDB Molecule:pyrroline-5-carboxylate reductase 1;
PDBTitle: crystal structure of human pyrroline-5-carboxylate2 reductase

Phyre2

PDB 3tri chain B

3D model

Region: 2 - 269
Aligned: 267
Modelled: 268
Confidence: 100.0%
Identity: 35%
PDB header:oxidoreductase
Chain: B: PDB Molecule:pyrroline-5-carboxylate reductase;
PDBTitle: structure of a pyrroline-5-carboxylate reductase (proc) from coxiella2 burnetii

Phyre2

PDB 2ahr chain B

3D model

Region: 3 - 266
Aligned: 256
Modelled: 263
Confidence: 100.0%
Identity: 34%
PDB header:oxidoreductase
Chain: B: PDB Molecule:putative pyrroline carboxylate reductase;
PDBTitle: crystal structures of 1-pyrroline-5-carboxylate reductase from human2 pathogen streptococcus pyogenes

Phyre2

PDB 2rcy chain B

3D model

Region: 1 - 267
Aligned: 251
Modelled: 265
Confidence: 100.0%
Identity: 34%
PDB header:oxidoreductase
Chain: B: PDB Molecule:pyrroline carboxylate reductase;
PDBTitle: crystal structure of plasmodium falciparum pyrroline carboxylate2 reductase (mal13p1.284) with nadp bound

Phyre2

PDB 2ag8 chain A

3D model

Region: 5 - 268
Aligned: 257
Modelled: 261
Confidence: 100.0%
Identity: 30%
PDB header:oxidoreductase
Chain: A: PDB Molecule:pyrroline-5-carboxylate reductase;
PDBTitle: nadp complex of pyrroline-5-carboxylate reductase from neisseria2 meningitidis

Phyre2

PDB 2gra chain A

3D model

Region: 1 - 268
Aligned: 266
Modelled: 268
Confidence: 100.0%
Identity: 37%
PDB header:oxidoreductase
Chain: A: PDB Molecule:pyrroline-5-carboxylate reductase 1;
PDBTitle: crystal structure of human pyrroline-5-carboxylate reductase complexed2 with nadp

Phyre2

PDB 3gt0 chain A

3D model

Region: 2 - 219
Aligned: 215
Modelled: 218
Confidence: 100.0%
Identity: 47%
PDB header:oxidoreductase
Chain: A: PDB Molecule:pyrroline-5-carboxylate reductase;
PDBTitle: crystal structure of pyrroline 5-carboxylate reductase from bacillus2 cereus. northeast structural genomics consortium target bcr38b

Phyre2

PDB 3d1l chain B

3D model

Region: 2 - 262
Aligned: 253
Modelled: 261
Confidence: 100.0%
Identity: 13%
PDB header:oxidoreductase
Chain: B: PDB Molecule:putative nadp oxidoreductase bf3122;
PDBTitle: crystal structure of putative nadp oxidoreductase bf3122 from2 bacteroides fragilis

Phyre2

PDB 3c24 chain A

3D model

Region: 3 - 252
Aligned: 243
Modelled: 250
Confidence: 100.0%
Identity: 16%
PDB header:oxidoreductase
Chain: A: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of a putative oxidoreductase (yp_511008.1) from2 jannaschia sp. ccs1 at 1.62 a resolution

Phyre2

PDB 3b1f chain A

3D model

Region: 2 - 269
Aligned: 260
Modelled: 268
Confidence: 100.0%
Identity: 16%
PDB header:oxidoreductase
Chain: A: PDB Molecule:putative prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from streptococcus2 mutans

Phyre2

PDB 3ggp chain A

3D model

Region: 1 - 268
Aligned: 260
Modelled: 265
Confidence: 100.0%
Identity: 16%
PDB header:oxidoreductase
Chain: A: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from a. aeolicus in2 complex with hydroxyphenyl propionate and nad+

Phyre2

PDB 3dzb chain A

3D model

Region: 3 - 268
Aligned: 258
Modelled: 266
Confidence: 100.0%
Identity: 17%
PDB header:biosynthetic protein
Chain: A: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from streptococcus2 thermophilus

Phyre2

PDB 3l6d chain B

3D model

Region: 1 - 269
Aligned: 263
Modelled: 269
Confidence: 100.0%
Identity: 13%
PDB header:oxidoreductase
Chain: B: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of putative oxidoreductase from pseudomonas putida2 kt2440

Phyre2

PDB 2g5c chain D

3D model

Region: 2 - 265
Aligned: 256
Modelled: 263
Confidence: 100.0%
Identity: 16%
PDB header:oxidoreductase
Chain: D: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from aquifex aeolicus

Phyre2

PDB 3g0o chain A

3D model

Region: 4 - 268
Aligned: 257
Modelled: 265
Confidence: 100.0%
Identity: 19%
PDB header:oxidoreductase
Chain: A: PDB Molecule:3-hydroxyisobutyrate dehydrogenase;
PDBTitle: crystal structure of 3-hydroxyisobutyrate dehydrogenase2 (ygbj) from salmonella typhimurium

Phyre2

PDB 2pv7 chain B

3D model

Region: 3 - 268
Aligned: 245
Modelled: 249
Confidence: 100.0%
Identity: 16%
PDB header:isomerase, oxidoreductase
Chain: B: PDB Molecule:t-protein [includes: chorismate mutase (ec 5.4.99.5) (cm)
PDBTitle: crystal structure of chorismate mutase / prephenate dehydrogenase2 (tyra) (1574749) from haemophilus influenzae rd at 2.00 a resolution

Phyre2

PDB 3qsg chain A

3D model

Region: 3 - 267
Aligned: 257
Modelled: 264
Confidence: 100.0%
Identity: 15%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:nad-binding phosphogluconate dehydrogenase-like protein;
PDBTitle: crystal structure of nad-binding phosphogluconate dehydrogenase-like2 protein from alicyclobacillus acidocaldarius

Phyre2

PDB 2f1k chain D

3D model

Region: 4 - 266
Aligned: 254
Modelled: 263
Confidence: 99.9%
Identity: 15%
PDB header:oxidoreductase
Chain: D: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of synechocystis arogenate dehydrogenase

Phyre2

PDB 2ahr chain A domain 2

3D model

Region: 3 - 162
Aligned: 152
Modelled: 159
Confidence: 99.9%
Identity: 31%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain

Phyre2

PDB 3ktd chain C

3D model

Region: 1 - 245
Aligned: 231
Modelled: 245
Confidence: 99.9%
Identity: 16%
PDB header:oxidoreductase
Chain: C: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of a putative prephenate dehydrogenase (cgl0226)2 from corynebacterium glutamicum atcc 13032 at 2.60 a resolution

Phyre2
1

c2izzE_
2

c3triB_
3

c2ahrB_
4

c2rcyB_
5

c2ag8A_
6

c2graA_
7

c3gt0A_
8

c3d1lB_
9

c3c24A_
10

c3b1fA_
11

c3ggpA_
12

c3dzbA_
13

c3l6dB_
14

c2g5cD_
15

c3g0oA_
16

c2pv7B_
17

c3qsgA_
18

c2f1kD_
19

d2ahra2
20

c3ktdC_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2izzE_



100.0 37 PDB header:oxidoreductase
Chain: E: PDB Molecule:pyrroline-5-carboxylate reductase 1;
PDBTitle: crystal structure of human pyrroline-5-carboxylate2 reductase
2c3triB_



100.0 35 PDB header:oxidoreductase
Chain: B: PDB Molecule:pyrroline-5-carboxylate reductase;
PDBTitle: structure of a pyrroline-5-carboxylate reductase (proc) from coxiella2 burnetii
3c2ahrB_



100.0 34 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative pyrroline carboxylate reductase;
PDBTitle: crystal structures of 1-pyrroline-5-carboxylate reductase from human2 pathogen streptococcus pyogenes
4c2rcyB_



100.0 34 PDB header:oxidoreductase
Chain: B: PDB Molecule:pyrroline carboxylate reductase;
PDBTitle: crystal structure of plasmodium falciparum pyrroline carboxylate2 reductase (mal13p1.284) with nadp bound
5c2ag8A_



100.0 30 PDB header:oxidoreductase
Chain: A: PDB Molecule:pyrroline-5-carboxylate reductase;
PDBTitle: nadp complex of pyrroline-5-carboxylate reductase from neisseria2 meningitidis
6c2graA_



100.0 37 PDB header:oxidoreductase
Chain: A: PDB Molecule:pyrroline-5-carboxylate reductase 1;
PDBTitle: crystal structure of human pyrroline-5-carboxylate reductase complexed2 with nadp
7c3gt0A_



100.0 47 PDB header:oxidoreductase
Chain: A: PDB Molecule:pyrroline-5-carboxylate reductase;
PDBTitle: crystal structure of pyrroline 5-carboxylate reductase from bacillus2 cereus. northeast structural genomics consortium target bcr38b
8c3d1lB_



100.0 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative nadp oxidoreductase bf3122;
PDBTitle: crystal structure of putative nadp oxidoreductase bf3122 from2 bacteroides fragilis
9c3c24A_



100.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of a putative oxidoreductase (yp_511008.1) from2 jannaschia sp. ccs1 at 1.62 a resolution
10c3b1fA_



100.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from streptococcus2 mutans
11c3ggpA_



100.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from a. aeolicus in2 complex with hydroxyphenyl propionate and nad+
12c3dzbA_



100.0 17 PDB header:biosynthetic protein
Chain: A: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from streptococcus2 thermophilus
13c3l6dB_



100.0 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of putative oxidoreductase from pseudomonas putida2 kt2440
14c2g5cD_



100.0 16 PDB header:oxidoreductase
Chain: D: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from aquifex aeolicus
15c3g0oA_



100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-hydroxyisobutyrate dehydrogenase;
PDBTitle: crystal structure of 3-hydroxyisobutyrate dehydrogenase2 (ygbj) from salmonella typhimurium
16c2pv7B_



100.0 16 PDB header:isomerase, oxidoreductase
Chain: B: PDB Molecule:t-protein [includes: chorismate mutase (ec 5.4.99.5) (cm)
PDBTitle: crystal structure of chorismate mutase / prephenate dehydrogenase2 (tyra) (1574749) from haemophilus influenzae rd at 2.00 a resolution
17c3qsgA_



100.0 15 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:nad-binding phosphogluconate dehydrogenase-like protein;
PDBTitle: crystal structure of nad-binding phosphogluconate dehydrogenase-like2 protein from alicyclobacillus acidocaldarius
18c2f1kD_



99.9 15 PDB header:oxidoreductase
Chain: D: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of synechocystis arogenate dehydrogenase
19d2ahra2



99.9 31 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
20c3ktdC_



99.9 16 PDB header:oxidoreductase
Chain: C: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of a putative prephenate dehydrogenase (cgl0226)2 from corynebacterium glutamicum atcc 13032 at 2.60 a resolution
21c2uyyD_



not modelled 99.9 18 PDB header:cytokine
Chain: D: PDB Molecule:n-pac protein;
PDBTitle: structure of the cytokine-like nuclear factor n-pac
22d1yqga2



not modelled 99.9 29 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
23c3pduF_



not modelled 99.9 14 PDB header:oxidoreductase
Chain: F: PDB Molecule:3-hydroxyisobutyrate dehydrogenase family protein;
PDBTitle: crystal structure of gamma-hydroxybutyrate dehydrogenase from2 geobacter sulfurreducens in complex with nadp+
24c3cumA_



not modelled 99.9 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable 3-hydroxyisobutyrate dehydrogenase;
PDBTitle: crystal structure of a possible 3-hydroxyisobutyrate dehydrogenase2 from pseudomonas aeruginosa pao1
25c1vpdA_



not modelled 99.9 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:tartronate semialdehyde reductase;
PDBTitle: x-ray crystal structure of tartronate semialdehyde reductase2 [salmonella typhimurium lt2]
26c3pefA_



not modelled 99.9 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase, nad-binding;
PDBTitle: crystal structure of gamma-hydroxybutyrate dehydrogenase from2 geobacter metallireducens in complex with nadp+
27c2p4qA_



not modelled 99.9 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase, decarboxylating 1;
PDBTitle: crystal structure analysis of gnd1 in saccharomyces cerevisiae
28c2cvzD_



not modelled 99.9 15 PDB header:oxidoreductase
Chain: D: PDB Molecule:3-hydroxyisobutyrate dehydrogenase;
PDBTitle: structure of hydroxyisobutyrate dehydrogenase from thermus2 thermophilus hb8
29c3ckyA_



not modelled 99.9 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-hydroxymethyl glutarate dehydrogenase;
PDBTitle: structural and kinetic properties of a beta-hydroxyacid dehydrogenase2 involved in nicotinate fermentation
30c3dojA_



not modelled 99.9 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:dehydrogenase-like protein;
PDBTitle: structure of glyoxylate reductase 1 from arabidopsis2 (atglyr1)
31c2iz1C_



not modelled 99.9 13 PDB header:oxidoreductase
Chain: C: PDB Molecule:6-phosphogluconate dehydrogenase, decarboxylating;
PDBTitle: 6pdh complexed with pex inhibitor synchrotron data
32c1pgqA_



not modelled 99.9 14 PDB header:oxidoreductase (choh(d)-nadp+(a))
Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase;
PDBTitle: crystallographic study of coenzyme, coenzyme analogue and substrate2 binding in 6-phosphogluconate dehydrogenase: implications for nadp3 specificity and the enzyme mechanism
33c1i36A_



not modelled 99.9 11 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:conserved hypothetical protein mth1747;
PDBTitle: structure of conserved protein mth1747 of unknown function2 reveals structural similarity with 3-hydroxyacid3 dehydrogenases
34c1pgjA_



not modelled 99.9 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase;
PDBTitle: x-ray structure of 6-phosphogluconate dehydrogenase from the protozoan2 parasite t. brucei
35c3fwnB_



not modelled 99.9 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:6-phosphogluconate dehydrogenase, decarboxylating;
PDBTitle: dimeric 6-phosphogluconate dehydrogenase complexed with 6-2 phosphogluconate and 2'-monophosphoadenosine-5'-diphosphate
36d1yqga1



not modelled 99.9 32 Fold:6-phosphogluconate dehydrogenase C-terminal domain-like
Superfamily:6-phosphogluconate dehydrogenase C-terminal domain-like
Family:ProC C-terminal domain-like
37c1yb4A_



not modelled 99.9 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:tartronic semialdehyde reductase;
PDBTitle: crystal structure of the tartronic semialdehyde reductase from2 salmonella typhimurium lt2
38c3k96B_



not modelled 99.9 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:glycerol-3-phosphate dehydrogenase [nad(p)+];
PDBTitle: 2.1 angstrom resolution crystal structure of glycerol-3-phosphate2 dehydrogenase (gpsa) from coxiella burnetii
39c2ep9A_



not modelled 99.9 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:l-gulonate 3-dehydrogenase;
PDBTitle: crystal structure of the rabbit l-gulonate 3-dehydrogenase2 (nadh form)
40c2gf2B_



not modelled 99.9 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-hydroxyisobutyrate dehydrogenase;
PDBTitle: crystal structure of human hydroxyisobutyrate dehydrogenase
41c3qhaB_



not modelled 99.9 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of a putative oxidoreductase from mycobacterium2 avium 104
42d2ahra1



not modelled 99.9 38 Fold:6-phosphogluconate dehydrogenase C-terminal domain-like
Superfamily:6-phosphogluconate dehydrogenase C-terminal domain-like
Family:ProC C-terminal domain-like
43c2i76B_



not modelled 99.8 13 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:hypothetical protein;
PDBTitle: crystal structure of protein tm1727 from thermotoga maritima
44c1m67A_



not modelled 99.8 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:glycerol-3-phosphate dehydrogenase;
PDBTitle: crystal structure of leishmania mexicana gpdh complexed with inhibitor2 2-bromo-6-hydroxy-purine
45c1np3B_



not modelled 99.8 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:ketol-acid reductoisomerase;
PDBTitle: crystal structure of class i acetohydroxy acid isomeroreductase from2 pseudomonas aeruginosa
46d1f0ya2



not modelled 99.8 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
47c3dttA_



not modelled 99.8 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadp oxidoreductase;
PDBTitle: crystal structure of a putative f420 dependent nadp-reductase2 (arth_0613) from arthrobacter sp. fb24 at 1.70 a resolution
48c1m75B_



not modelled 99.8 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-hydroxyacyl-coa dehydrogenase;
PDBTitle: crystal structure of the n208s mutant of l-3-hydroxyacyl-2 coa dehydrogenase in complex with nad and acetoacetyl-coa
49c3hn2A_



not modelled 99.8 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-dehydropantoate 2-reductase;
PDBTitle: crystal structure of 2-dehydropantoate 2-reductase from geobacter2 metallireducens gs-15
50c2ew2B_



not modelled 99.8 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:2-dehydropantoate 2-reductase, putative;
PDBTitle: crystal structure of the putative 2-dehydropantoate 2-reductase from2 enterococcus faecalis
51d1wdka3



not modelled 99.8 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
52c3k6jA_



not modelled 99.8 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:protein f01g10.3, confirmed by transcript evidence;
PDBTitle: crystal structure of the dehydrogenase part of multifuctional enzyme 12 from c.elegans
53c3mogA_



not modelled 99.7 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable 3-hydroxybutyryl-coa dehydrogenase;
PDBTitle: crystal structure of 3-hydroxybutyryl-coa dehydrogenase from2 escherichia coli k12 substr. mg1655
54c3gg2B_



not modelled 99.7 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:sugar dehydrogenase, udp-glucose/gdp-mannose
PDBTitle: crystal structure of udp-glucose 6-dehydrogenase from2 porphyromonas gingivalis bound to product udp-glucuronate
55d3cuma2



not modelled 99.7 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
56d1n1ea2



not modelled 99.7 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
57d1jaya_



not modelled 99.7 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
58d1vpda2



not modelled 99.7 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
59c1wpqB_



not modelled 99.7 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:glycerol-3-phosphate dehydrogenase [nad+],
PDBTitle: ternary complex of glycerol 3-phosphate dehydrogenase 12 with nad and dihydroxyactone
60d2f1ka2



not modelled 99.7 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
61c1zcjA_



not modelled 99.7 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:peroxisomal bifunctional enzyme;
PDBTitle: crystal structure of 3-hydroxyacyl-coa dehydrogenase
62d2cvza2



not modelled 99.7 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
63d2g5ca2



not modelled 99.7 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
64c1mv8A_



not modelled 99.7 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:gdp-mannose 6-dehydrogenase;
PDBTitle: 1.55 a crystal structure of a ternary complex of gdp-mannose2 dehydrogenase from psuedomonas aeruginosa
65c1bg6A_



not modelled 99.7 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:n-(1-d-carboxylethyl)-l-norvaline dehydrogenase;
PDBTitle: crystal structure of the n-(1-d-carboxylethyl)-l-norvaline2 dehydrogenase from arthrobacter sp. strain 1c
66c2ofpB_



not modelled 99.7 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:ketopantoate reductase;
PDBTitle: crystal structure of escherichia coli ketopantoate2 reductase in a ternary complex with nadp+ and pantoate
67c1yj8C_



not modelled 99.7 14 PDB header:oxidoreductase
Chain: C: PDB Molecule:glycerol-3-phosphate dehydrogenase;
PDBTitle: initial structural analysis of plasmodium falciparum glycerol-3-2 phosphate dehydrogenase
68c3hwrA_



not modelled 99.7 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-dehydropantoate 2-reductase;
PDBTitle: crystal structure of pane/apba family ketopantoate reductase2 (yp_299159.1) from ralstonia eutropha jmp134 at 2.15 a resolution
69c2y0dB_



not modelled 99.7 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:udp-glucose dehydrogenase;
PDBTitle: bcec mutation y10k
70c2x58B_



not modelled 99.7 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:peroxisomal bifunctional enzyme;
PDBTitle: the crystal structure of mfe1 liganded with coa
71d2pgda2



not modelled 99.7 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
72c1txgA_



not modelled 99.7 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:glycerol-3-phosphate dehydrogenase [nad(p)+];
PDBTitle: structure of glycerol-3-phosphate dehydrogenase from archaeoglobus2 fulgidus
73c1ks9A_



not modelled 99.7 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-dehydropantoate 2-reductase;
PDBTitle: ketopantoate reductase from escherichia coli
74c2wtbA_



not modelled 99.7 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:fatty acid multifunctional protein (atmfp2);
PDBTitle: arabidopsis thaliana multifuctional protein, mfp2
75c1z82A_



not modelled 99.7 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:glycerol-3-phosphate dehydrogenase;
PDBTitle: crystal structure of glycerol-3-phosphate dehydrogenase (tm0378) from2 thermotoga maritima at 2.00 a resolution
76d2pv7a2



not modelled 99.7 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
77d2i76a2



not modelled 99.7 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
78d1i36a2



not modelled 99.7 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
79c2d3tB_



not modelled 99.7 16 PDB header:lyase, oxidoreductase/transferase
Chain: B: PDB Molecule:fatty oxidation complex alpha subunit;
PDBTitle: fatty acid beta-oxidation multienzyme complex from2 pseudomonas fragi, form v
80c3ghyA_



not modelled 99.7 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:ketopantoate reductase protein;
PDBTitle: crystal structure of a putative ketopantoate reductase from ralstonia2 solanacearum molk2
81d1np3a2



not modelled 99.7 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
82d1txga2



not modelled 99.6 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
83c2q3eH_



not modelled 99.6 14 PDB header:oxidoreductase
Chain: H: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: structure of human udp-glucose dehydrogenase complexed with nadh and2 udp-glucose
84c2o3jC_



not modelled 99.6 18 PDB header:oxidoreductase
Chain: C: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: structure of caenorhabditis elegans udp-glucose dehydrogenase
85d1pgja2



not modelled 99.6 10 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
86c3ojlA_



not modelled 99.6 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:cap5o;
PDBTitle: native structure of the udp-n-acetyl-mannosamine dehydrogenase cap5o2 from staphylococcus aureus
87c2vq3B_



not modelled 99.6 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:metalloreductase steap3;
PDBTitle: crystal structure of the membrane proximal oxidoreductase2 domain of human steap3, the dominant ferric reductase of3 the erythroid transferrin cycle
88c1zejA_



not modelled 99.6 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-hydroxyacyl-coa dehydrogenase;
PDBTitle: crystal structure of the 3-hydroxyacyl-coa dehydrogenase (hbd-9,2 af2017) from archaeoglobus fulgidus dsm 4304 at 2.00 a resolution
89c3prjB_



not modelled 99.6 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: role of packing defects in the evolution of allostery and induced fit2 in human udp-glucose dehydrogenase.
90c3plnA_



not modelled 99.6 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: crystal structure of klebsiella pneumoniae udp-glucose 6-dehydrogenase2 complexed with udp-glucose
91c3g79A_



not modelled 99.6 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:ndp-n-acetyl-d-galactosaminuronic acid dehydrogenase;
PDBTitle: crystal structure of ndp-n-acetyl-d-galactosaminuronic acid2 dehydrogenase from methanosarcina mazei go1
92c3g17H_



not modelled 99.6 12 PDB header:structural genomics, unknown function
Chain: H: PDB Molecule:similar to 2-dehydropantoate 2-reductase;
PDBTitle: structure of putative 2-dehydropantoate 2-reductase from2 staphylococcus aureus
93c3egoB_



not modelled 99.6 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:probable 2-dehydropantoate 2-reductase;
PDBTitle: crystal structure of probable 2-dehydropantoate 2-reductase2 pane from bacillus subtilis
94c1dliA_



not modelled 99.5 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:udp-glucose dehydrogenase;
PDBTitle: the first structure of udp-glucose dehydrogenase (udpgdh) reveals the2 catalytic residues necessary for the two-fold oxidation
95c3dfuB_



not modelled 99.5 12 PDB header:oxidoreductase
Chain: B: PDB Molecule:uncharacterized protein from 6-phosphogluconate
PDBTitle: crystal structure of a putative rossmann-like dehydrogenase (cgl2689)2 from corynebacterium glutamicum at 2.07 a resolution
96d1bg6a2



not modelled 99.5 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
97c2qytA_



not modelled 99.5 11 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-dehydropantoate 2-reductase;
PDBTitle: crystal structure of 2-dehydropantoate 2-reductase from porphyromonas2 gingivalis w83
98d1mv8a2



not modelled 99.4 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
99d1ks9a2



not modelled 99.4 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
100c3c7cB_



not modelled 99.4 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:octopine dehydrogenase;
PDBTitle: a structural basis for substrate and stereo selectivity in2 octopine dehydrogenase (odh-nadh-l-arginine)
101c2rafC_



not modelled 99.4 17 PDB header:oxidoreductase
Chain: C: PDB Molecule:putative dinucleotide-binding oxidoreductase;
PDBTitle: crystal structure of putative dinucleotide-binding2 oxidoreductase (np_786167.1) from lactobacillus plantarum3 at 1.60 a resolution
102d1dlja2



not modelled 99.4 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
103c1yveK_



not modelled 99.3 17 PDB header:oxidoreductase
Chain: K: PDB Molecule:acetohydroxy acid isomeroreductase;
PDBTitle: acetohydroxy acid isomeroreductase complexed with nadph,2 magnesium and inhibitor ipoha (n-hydroxy-n-3 isopropyloxamate)
104c3i83B_



not modelled 99.1 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:2-dehydropantoate 2-reductase;
PDBTitle: crystal structure of 2-dehydropantoate 2-reductase from methylococcus2 capsulatus
105d1uxja1



not modelled 99.1 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
106d1ez4a1



not modelled 99.0 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
107c1yrlD_



not modelled 99.0 15 PDB header:oxidoreductase
Chain: D: PDB Molecule:ketol-acid reductoisomerase;
PDBTitle: escherichia coli ketol-acid reductoisomerase
108c3euwB_



not modelled 98.9 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:myo-inositol dehydrogenase;
PDBTitle: crystal structure of a myo-inositol dehydrogenase from corynebacterium2 glutamicum atcc 13032
109c1e5lA_



not modelled 98.9 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:saccharopine reductase;
PDBTitle: apo saccharopine reductase from magnaporthe grisea
110c1gpjA_



not modelled 98.9 22 PDB header:reductase
Chain: A: PDB Molecule:glutamyl-trna reductase;
PDBTitle: glutamyl-trna reductase from methanopyrus kandleri
111c2axqA_



not modelled 98.8 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:saccharopine dehydrogenase;
PDBTitle: apo histidine-tagged saccharopine dehydrogenase (l-glu2 forming) from saccharomyces cerevisiae
112d1gdha1



not modelled 98.8 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
113d1e5qa1



not modelled 98.8 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
114d9ldta1



not modelled 98.8 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
115d1gpja2



not modelled 98.8 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
116c3moiA_



not modelled 98.8 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable dehydrogenase;
PDBTitle: the crystal structure of the putative dehydrogenase from bordetella2 bronchiseptica rb50
117c2rirA_



not modelled 98.8 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:dipicolinate synthase, a chain;
PDBTitle: crystal structure of dipicolinate synthase, a chain, from bacillus2 subtilis
118c3db2C_



not modelled 98.8 14 PDB header:oxidoreductase
Chain: C: PDB Molecule:putative nadph-dependent oxidoreductase;
PDBTitle: crystal structure of a putative nadph-dependent oxidoreductase2 (dhaf_2064) from desulfitobacterium hafniense dcb-2 at 1.70 a3 resolution
119d1qmga2



not modelled 98.8 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
120d2naca1



not modelled 98.8 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0