Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP76373
DateThu Jan 5 12:22:27 GMT 2012
Unique Job IDbb815dbe4323e101

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1dliA_
Top template information
PDB header:oxidoreductase
Chain: A: PDB Molecule:udp-glucose dehydrogenase;
PDBTitle: the first structure of udp-glucose dehydrogenase (udpgdh) reveals the2 catalytic residues necessary for the two-fold oxidation
Confidence and coverage
Confidence:100.0% Coverage:100%
388 residues (100% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MKITISGTGYVGLSNGLLIAQNHEVVALDILPSRVAMLNDRISPIVDKEIQQFLQSDKIH
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   .........70.........80.........90.........100.........110.........120
Sequence  FNATLDKNEAYRDADYVIIATPTDYDPKTNYFNTSSVESVIKDVVEINPYAVMVIKSTVP
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?

































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   .........130.........140.........150.........160.........170.........180
Sequence  VGFTAAMHKKYRTENIIFSPEFLREGKALYDNLHPSRIVIGERSERAERFAALLQEGAIK
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   .........190.........200.........210.........220.........230.........240
Sequence  QNIPMLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNSRQIIEGVCLDPRIGN
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   .........250.........260.........270.........280.........290.........300
Sequence  HYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAIVDANRTRKDFIADAILSRKPQVVG
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   .........310.........320.........330.........340.........350.........360
Sequence  IYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVIIYEPVMKEDSFFNSRLERDLATFKQQA
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   .........370.........380........
Sequence  DVIISNRMAEELKDVADKVYTRDLFGSD
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?

???
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1dli chain A

3D model

Region: 1 - 388
Aligned: 388
Modelled: 388
Confidence: 100.0%
Identity: 56%
PDB header:oxidoreductase
Chain: A: PDB Molecule:udp-glucose dehydrogenase;
PDBTitle: the first structure of udp-glucose dehydrogenase (udpgdh) reveals the2 catalytic residues necessary for the two-fold oxidation

Phyre2

PDB 2q3e chain H

3D model

Region: 1 - 386
Aligned: 385
Modelled: 386
Confidence: 100.0%
Identity: 25%
PDB header:oxidoreductase
Chain: H: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: structure of human udp-glucose dehydrogenase complexed with nadh and2 udp-glucose

Phyre2

PDB 3prj chain B

3D model

Region: 1 - 375
Aligned: 374
Modelled: 375
Confidence: 100.0%
Identity: 25%
PDB header:oxidoreductase
Chain: B: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: role of packing defects in the evolution of allostery and induced fit2 in human udp-glucose dehydrogenase.

Phyre2

PDB 2o3j chain C

3D model

Region: 1 - 387
Aligned: 386
Modelled: 387
Confidence: 100.0%
Identity: 25%
PDB header:oxidoreductase
Chain: C: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: structure of caenorhabditis elegans udp-glucose dehydrogenase

Phyre2

PDB 3pln chain A

3D model

Region: 1 - 386
Aligned: 375
Modelled: 375
Confidence: 100.0%
Identity: 82%
PDB header:oxidoreductase
Chain: A: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: crystal structure of klebsiella pneumoniae udp-glucose 6-dehydrogenase2 complexed with udp-glucose

Phyre2

PDB 2y0d chain B

3D model

Region: 1 - 375
Aligned: 369
Modelled: 375
Confidence: 100.0%
Identity: 29%
PDB header:oxidoreductase
Chain: B: PDB Molecule:udp-glucose dehydrogenase;
PDBTitle: bcec mutation y10k

Phyre2

PDB 3gg2 chain B

3D model

Region: 1 - 375
Aligned: 371
Modelled: 375
Confidence: 100.0%
Identity: 26%
PDB header:oxidoreductase
Chain: B: PDB Molecule:sugar dehydrogenase, udp-glucose/gdp-mannose
PDBTitle: crystal structure of udp-glucose 6-dehydrogenase from2 porphyromonas gingivalis bound to product udp-glucuronate

Phyre2

PDB 3g79 chain A

3D model

Region: 1 - 375
Aligned: 370
Modelled: 375
Confidence: 100.0%
Identity: 23%
PDB header:oxidoreductase
Chain: A: PDB Molecule:ndp-n-acetyl-d-galactosaminuronic acid dehydrogenase;
PDBTitle: crystal structure of ndp-n-acetyl-d-galactosaminuronic acid2 dehydrogenase from methanosarcina mazei go1

Phyre2

PDB 1mv8 chain A

3D model

Region: 1 - 387
Aligned: 383
Modelled: 387
Confidence: 100.0%
Identity: 27%
PDB header:oxidoreductase
Chain: A: PDB Molecule:gdp-mannose 6-dehydrogenase;
PDBTitle: 1.55 a crystal structure of a ternary complex of gdp-mannose2 dehydrogenase from psuedomonas aeruginosa

Phyre2

PDB 3ojl chain A

3D model

Region: 2 - 380
Aligned: 364
Modelled: 379
Confidence: 100.0%
Identity: 24%
PDB header:oxidoreductase
Chain: A: PDB Molecule:cap5o;
PDBTitle: native structure of the udp-n-acetyl-mannosamine dehydrogenase cap5o2 from staphylococcus aureus

Phyre2

PDB 1dlj chain A domain 2

3D model

Region: 1 - 189
Aligned: 189
Modelled: 189
Confidence: 100.0%
Identity: 50%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain

Phyre2

PDB 1vpd chain A

3D model

Region: 1 - 285
Aligned: 255
Modelled: 252
Confidence: 100.0%
Identity: 16%
PDB header:oxidoreductase
Chain: A: PDB Molecule:tartronate semialdehyde reductase;
PDBTitle: x-ray crystal structure of tartronate semialdehyde reductase2 [salmonella typhimurium lt2]

Phyre2

PDB 3cum chain A

3D model

Region: 2 - 279
Aligned: 248
Modelled: 244
Confidence: 100.0%
Identity: 19%
PDB header:oxidoreductase
Chain: A: PDB Molecule:probable 3-hydroxyisobutyrate dehydrogenase;
PDBTitle: crystal structure of a possible 3-hydroxyisobutyrate dehydrogenase2 from pseudomonas aeruginosa pao1

Phyre2

PDB 1dlj chain A domain 1

3D model

Region: 190 - 287
Aligned: 98
Modelled: 98
Confidence: 100.0%
Identity: 71%
Fold: 6-phosphogluconate dehydrogenase C-terminal domain-like
Superfamily: 6-phosphogluconate dehydrogenase C-terminal domain-like
Family: UDP-glucose/GDP-mannose dehydrogenase dimerisation domain

Phyre2

PDB 2cvz chain D

3D model

Region: 2 - 331
Aligned: 272
Modelled: 280
Confidence: 100.0%
Identity: 16%
PDB header:oxidoreductase
Chain: D: PDB Molecule:3-hydroxyisobutyrate dehydrogenase;
PDBTitle: structure of hydroxyisobutyrate dehydrogenase from thermus2 thermophilus hb8

Phyre2

PDB 3cky chain A

3D model

Region: 1 - 285
Aligned: 257
Modelled: 267
Confidence: 100.0%
Identity: 19%
PDB header:oxidoreductase
Chain: A: PDB Molecule:2-hydroxymethyl glutarate dehydrogenase;
PDBTitle: structural and kinetic properties of a beta-hydroxyacid dehydrogenase2 involved in nicotinate fermentation

Phyre2

PDB 1yb4 chain A

3D model

Region: 1 - 299
Aligned: 268
Modelled: 273
Confidence: 100.0%
Identity: 15%
PDB header:oxidoreductase
Chain: A: PDB Molecule:tartronic semialdehyde reductase;
PDBTitle: crystal structure of the tartronic semialdehyde reductase from2 salmonella typhimurium lt2

Phyre2

PDB 1mv8 chain A domain 1

3D model

Region: 190 - 283
Aligned: 94
Modelled: 94
Confidence: 100.0%
Identity: 30%
Fold: 6-phosphogluconate dehydrogenase C-terminal domain-like
Superfamily: 6-phosphogluconate dehydrogenase C-terminal domain-like
Family: UDP-glucose/GDP-mannose dehydrogenase dimerisation domain

Phyre2

PDB 3g0o chain A

3D model

Region: 1 - 285
Aligned: 255
Modelled: 263
Confidence: 100.0%
Identity: 16%
PDB header:oxidoreductase
Chain: A: PDB Molecule:3-hydroxyisobutyrate dehydrogenase;
PDBTitle: crystal structure of 3-hydroxyisobutyrate dehydrogenase2 (ygbj) from salmonella typhimurium

Phyre2

PDB 1mv8 chain A domain 2

3D model

Region: 1 - 189
Aligned: 186
Modelled: 189
Confidence: 99.9%
Identity: 25%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain

Phyre2
1

c1dliA_
2

c2q3eH_
3

c3prjB_
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c2o3jC_
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c3plnA_
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c2y0dB_
7

c3gg2B_
8

c3g79A_
9

c1mv8A_
10

c3ojlA_
11

d1dlja2
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c1vpdA_
13

c3cumA_
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d1dlja1
15

c2cvzD_
16

c3ckyA_
17

c1yb4A_
18

d1mv8a1
19

c3g0oA_
20

d1mv8a2
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1dliA_



100.0 56 PDB header:oxidoreductase
Chain: A: PDB Molecule:udp-glucose dehydrogenase;
PDBTitle: the first structure of udp-glucose dehydrogenase (udpgdh) reveals the2 catalytic residues necessary for the two-fold oxidation
2c2q3eH_



100.0 25 PDB header:oxidoreductase
Chain: H: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: structure of human udp-glucose dehydrogenase complexed with nadh and2 udp-glucose
3c3prjB_



100.0 25 PDB header:oxidoreductase
Chain: B: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: role of packing defects in the evolution of allostery and induced fit2 in human udp-glucose dehydrogenase.
4c2o3jC_



100.0 25 PDB header:oxidoreductase
Chain: C: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: structure of caenorhabditis elegans udp-glucose dehydrogenase
5c3plnA_



100.0 82 PDB header:oxidoreductase
Chain: A: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: crystal structure of klebsiella pneumoniae udp-glucose 6-dehydrogenase2 complexed with udp-glucose
6c2y0dB_



100.0 29 PDB header:oxidoreductase
Chain: B: PDB Molecule:udp-glucose dehydrogenase;
PDBTitle: bcec mutation y10k
7c3gg2B_



100.0 26 PDB header:oxidoreductase
Chain: B: PDB Molecule:sugar dehydrogenase, udp-glucose/gdp-mannose
PDBTitle: crystal structure of udp-glucose 6-dehydrogenase from2 porphyromonas gingivalis bound to product udp-glucuronate
8c3g79A_



100.0 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:ndp-n-acetyl-d-galactosaminuronic acid dehydrogenase;
PDBTitle: crystal structure of ndp-n-acetyl-d-galactosaminuronic acid2 dehydrogenase from methanosarcina mazei go1
9c1mv8A_



100.0 27 PDB header:oxidoreductase
Chain: A: PDB Molecule:gdp-mannose 6-dehydrogenase;
PDBTitle: 1.55 a crystal structure of a ternary complex of gdp-mannose2 dehydrogenase from psuedomonas aeruginosa
10c3ojlA_



100.0 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:cap5o;
PDBTitle: native structure of the udp-n-acetyl-mannosamine dehydrogenase cap5o2 from staphylococcus aureus
11d1dlja2



100.0 50 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
12c1vpdA_



100.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:tartronate semialdehyde reductase;
PDBTitle: x-ray crystal structure of tartronate semialdehyde reductase2 [salmonella typhimurium lt2]
13c3cumA_



100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable 3-hydroxyisobutyrate dehydrogenase;
PDBTitle: crystal structure of a possible 3-hydroxyisobutyrate dehydrogenase2 from pseudomonas aeruginosa pao1
14d1dlja1



100.0 71 Fold:6-phosphogluconate dehydrogenase C-terminal domain-like
Superfamily:6-phosphogluconate dehydrogenase C-terminal domain-like
Family:UDP-glucose/GDP-mannose dehydrogenase dimerisation domain
15c2cvzD_



100.0 16 PDB header:oxidoreductase
Chain: D: PDB Molecule:3-hydroxyisobutyrate dehydrogenase;
PDBTitle: structure of hydroxyisobutyrate dehydrogenase from thermus2 thermophilus hb8
16c3ckyA_



100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-hydroxymethyl glutarate dehydrogenase;
PDBTitle: structural and kinetic properties of a beta-hydroxyacid dehydrogenase2 involved in nicotinate fermentation
17c1yb4A_



100.0 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:tartronic semialdehyde reductase;
PDBTitle: crystal structure of the tartronic semialdehyde reductase from2 salmonella typhimurium lt2
18d1mv8a1



100.0 30 Fold:6-phosphogluconate dehydrogenase C-terminal domain-like
Superfamily:6-phosphogluconate dehydrogenase C-terminal domain-like
Family:UDP-glucose/GDP-mannose dehydrogenase dimerisation domain
19c3g0oA_



100.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-hydroxyisobutyrate dehydrogenase;
PDBTitle: crystal structure of 3-hydroxyisobutyrate dehydrogenase2 (ygbj) from salmonella typhimurium
20d1mv8a2



99.9 25 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
21c1pgjA_



not modelled 99.9 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase;
PDBTitle: x-ray structure of 6-phosphogluconate dehydrogenase from the protozoan2 parasite t. brucei
22c3fwnB_



not modelled 99.9 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:6-phosphogluconate dehydrogenase, decarboxylating;
PDBTitle: dimeric 6-phosphogluconate dehydrogenase complexed with 6-2 phosphogluconate and 2'-monophosphoadenosine-5'-diphosphate
23c2p4qA_



not modelled 99.9 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase, decarboxylating 1;
PDBTitle: crystal structure analysis of gnd1 in saccharomyces cerevisiae
24c2iz1C_



not modelled 99.9 14 PDB header:oxidoreductase
Chain: C: PDB Molecule:6-phosphogluconate dehydrogenase, decarboxylating;
PDBTitle: 6pdh complexed with pex inhibitor synchrotron data
25c3qhaB_



not modelled 99.9 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of a putative oxidoreductase from mycobacterium2 avium 104
26c3qsgA_



not modelled 99.9 13 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:nad-binding phosphogluconate dehydrogenase-like protein;
PDBTitle: crystal structure of nad-binding phosphogluconate dehydrogenase-like2 protein from alicyclobacillus acidocaldarius
27c1pgqA_



not modelled 99.9 17 PDB header:oxidoreductase (choh(d)-nadp+(a))
Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase;
PDBTitle: crystallographic study of coenzyme, coenzyme analogue and substrate2 binding in 6-phosphogluconate dehydrogenase: implications for nadp3 specificity and the enzyme mechanism
28c3dojA_



not modelled 99.9 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:dehydrogenase-like protein;
PDBTitle: structure of glyoxylate reductase 1 from arabidopsis2 (atglyr1)
29c2uyyD_



not modelled 99.9 14 PDB header:cytokine
Chain: D: PDB Molecule:n-pac protein;
PDBTitle: structure of the cytokine-like nuclear factor n-pac
30c2gf2B_



not modelled 99.9 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-hydroxyisobutyrate dehydrogenase;
PDBTitle: crystal structure of human hydroxyisobutyrate dehydrogenase
31c3pefA_



not modelled 99.9 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase, nad-binding;
PDBTitle: crystal structure of gamma-hydroxybutyrate dehydrogenase from2 geobacter metallireducens in complex with nadp+
32c3l6dB_



not modelled 99.9 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of putative oxidoreductase from pseudomonas putida2 kt2440
33c3pduF_



not modelled 99.9 14 PDB header:oxidoreductase
Chain: F: PDB Molecule:3-hydroxyisobutyrate dehydrogenase family protein;
PDBTitle: crystal structure of gamma-hydroxybutyrate dehydrogenase from2 geobacter sulfurreducens in complex with nadp+
34c1m67A_



not modelled 99.9 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:glycerol-3-phosphate dehydrogenase;
PDBTitle: crystal structure of leishmania mexicana gpdh complexed with inhibitor2 2-bromo-6-hydroxy-purine
35c1i36A_



not modelled 99.9 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:conserved hypothetical protein mth1747;
PDBTitle: structure of conserved protein mth1747 of unknown function2 reveals structural similarity with 3-hydroxyacid3 dehydrogenases
36d1dlja3



not modelled 99.9 48 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:UDP-glucose/GDP-mannose dehydrogenase C-terminal domain
Family:UDP-glucose/GDP-mannose dehydrogenase C-terminal domain
37d1mv8a3



not modelled 99.9 25 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:UDP-glucose/GDP-mannose dehydrogenase C-terminal domain
Family:UDP-glucose/GDP-mannose dehydrogenase C-terminal domain
38c1bg6A_



not modelled 99.8 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:n-(1-d-carboxylethyl)-l-norvaline dehydrogenase;
PDBTitle: crystal structure of the n-(1-d-carboxylethyl)-l-norvaline2 dehydrogenase from arthrobacter sp. strain 1c
39c1yj8C_



not modelled 99.8 14 PDB header:oxidoreductase
Chain: C: PDB Molecule:glycerol-3-phosphate dehydrogenase;
PDBTitle: initial structural analysis of plasmodium falciparum glycerol-3-2 phosphate dehydrogenase
40c1txgA_



not modelled 99.8 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:glycerol-3-phosphate dehydrogenase [nad(p)+];
PDBTitle: structure of glycerol-3-phosphate dehydrogenase from archaeoglobus2 fulgidus
41c3k96B_



not modelled 99.8 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:glycerol-3-phosphate dehydrogenase [nad(p)+];
PDBTitle: 2.1 angstrom resolution crystal structure of glycerol-3-phosphate2 dehydrogenase (gpsa) from coxiella burnetii
42c1wpqB_



not modelled 99.7 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:glycerol-3-phosphate dehydrogenase [nad+],
PDBTitle: ternary complex of glycerol 3-phosphate dehydrogenase 12 with nad and dihydroxyactone
43d2pgda2



not modelled 99.7 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
44c2ew2B_



not modelled 99.7 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:2-dehydropantoate 2-reductase, putative;
PDBTitle: crystal structure of the putative 2-dehydropantoate 2-reductase from2 enterococcus faecalis
45c2ofpB_



not modelled 99.7 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:ketopantoate reductase;
PDBTitle: crystal structure of escherichia coli ketopantoate2 reductase in a ternary complex with nadp+ and pantoate
46d1vpda2



not modelled 99.7 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
47c3ghyA_



not modelled 99.7 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:ketopantoate reductase protein;
PDBTitle: crystal structure of a putative ketopantoate reductase from ralstonia2 solanacearum molk2
48c2ep9A_



not modelled 99.7 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:l-gulonate 3-dehydrogenase;
PDBTitle: crystal structure of the rabbit l-gulonate 3-dehydrogenase2 (nadh form)
49c2f1kD_



not modelled 99.7 14 PDB header:oxidoreductase
Chain: D: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of synechocystis arogenate dehydrogenase
50d3cuma2



not modelled 99.7 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
51c3d1lB_



not modelled 99.6 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative nadp oxidoreductase bf3122;
PDBTitle: crystal structure of putative nadp oxidoreductase bf3122 from2 bacteroides fragilis
52c1z82A_



not modelled 99.6 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:glycerol-3-phosphate dehydrogenase;
PDBTitle: crystal structure of glycerol-3-phosphate dehydrogenase (tm0378) from2 thermotoga maritima at 2.00 a resolution
53d1pgja2



not modelled 99.6 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
54c1ks9A_



not modelled 99.6 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-dehydropantoate 2-reductase;
PDBTitle: ketopantoate reductase from escherichia coli
55d2cvza2



not modelled 99.6 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
56d1f0ya2



not modelled 99.6 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
57c3hn2A_



not modelled 99.6 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-dehydropantoate 2-reductase;
PDBTitle: crystal structure of 2-dehydropantoate 2-reductase from geobacter2 metallireducens gs-15
58c3hwrA_



not modelled 99.6 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-dehydropantoate 2-reductase;
PDBTitle: crystal structure of pane/apba family ketopantoate reductase2 (yp_299159.1) from ralstonia eutropha jmp134 at 2.15 a resolution
59c3egoB_



not modelled 99.6 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:probable 2-dehydropantoate 2-reductase;
PDBTitle: crystal structure of probable 2-dehydropantoate 2-reductase2 pane from bacillus subtilis
60c3g17H_



not modelled 99.5 16 PDB header:structural genomics, unknown function
Chain: H: PDB Molecule:similar to 2-dehydropantoate 2-reductase;
PDBTitle: structure of putative 2-dehydropantoate 2-reductase from2 staphylococcus aureus
61c2g5cD_



not modelled 99.5 12 PDB header:oxidoreductase
Chain: D: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from aquifex aeolicus
62d1jaya_



not modelled 99.5 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
63d1i36a2



not modelled 99.5 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
64d1n1ea2



not modelled 99.5 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
65c2pv7B_



not modelled 99.5 16 PDB header:isomerase, oxidoreductase
Chain: B: PDB Molecule:t-protein [includes: chorismate mutase (ec 5.4.99.5) (cm)
PDBTitle: crystal structure of chorismate mutase / prephenate dehydrogenase2 (tyra) (1574749) from haemophilus influenzae rd at 2.00 a resolution
66c3triB_



not modelled 99.5 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:pyrroline-5-carboxylate reductase;
PDBTitle: structure of a pyrroline-5-carboxylate reductase (proc) from coxiella2 burnetii
67c2izzE_



not modelled 99.5 12 PDB header:oxidoreductase
Chain: E: PDB Molecule:pyrroline-5-carboxylate reductase 1;
PDBTitle: crystal structure of human pyrroline-5-carboxylate2 reductase
68d2f1ka2



not modelled 99.4 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
69c3dzbA_



not modelled 99.4 16 PDB header:biosynthetic protein
Chain: A: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from streptococcus2 thermophilus
70c3b1fA_



not modelled 99.4 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from streptococcus2 mutans
71c1m75B_



not modelled 99.4 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-hydroxyacyl-coa dehydrogenase;
PDBTitle: crystal structure of the n208s mutant of l-3-hydroxyacyl-2 coa dehydrogenase in complex with nad and acetoacetyl-coa
72c2graA_



not modelled 99.4 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:pyrroline-5-carboxylate reductase 1;
PDBTitle: crystal structure of human pyrroline-5-carboxylate reductase complexed2 with nadp
73c3dttA_



not modelled 99.4 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadp oxidoreductase;
PDBTitle: crystal structure of a putative f420 dependent nadp-reductase2 (arth_0613) from arthrobacter sp. fb24 at 1.70 a resolution
74c3k6jA_



not modelled 99.4 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:protein f01g10.3, confirmed by transcript evidence;
PDBTitle: crystal structure of the dehydrogenase part of multifuctional enzyme 12 from c.elegans
75c3gt0A_



not modelled 99.4 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:pyrroline-5-carboxylate reductase;
PDBTitle: crystal structure of pyrroline 5-carboxylate reductase from bacillus2 cereus. northeast structural genomics consortium target bcr38b
76c2ahrB_



not modelled 99.4 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative pyrroline carboxylate reductase;
PDBTitle: crystal structures of 1-pyrroline-5-carboxylate reductase from human2 pathogen streptococcus pyogenes
77d1bg6a2



not modelled 99.3 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
78d1txga2



not modelled 99.3 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
79d1a5za1



not modelled 99.3 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
80d1wdka3



not modelled 99.3 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
81c3ggpA_



not modelled 99.3 11 PDB header:oxidoreductase
Chain: A: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from a. aeolicus in2 complex with hydroxyphenyl propionate and nad+
82c3mogA_



not modelled 99.3 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable 3-hydroxybutyryl-coa dehydrogenase;
PDBTitle: crystal structure of 3-hydroxybutyryl-coa dehydrogenase from2 escherichia coli k12 substr. mg1655
83c3ktdC_



not modelled 99.3 12 PDB header:oxidoreductase
Chain: C: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of a putative prephenate dehydrogenase (cgl0226)2 from corynebacterium glutamicum atcc 13032 at 2.60 a resolution
84d1ojua1



not modelled 99.3 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
85d1i0za1



not modelled 99.3 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
86c2ag8A_



not modelled 99.3 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:pyrroline-5-carboxylate reductase;
PDBTitle: nadp complex of pyrroline-5-carboxylate reductase from neisseria2 meningitidis
87d1gv0a1



not modelled 99.3 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
88d2g5ca2



not modelled 99.3 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
89d9ldta1



not modelled 99.2 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
90d1hyha1



not modelled 99.2 25 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
91c1np3B_



not modelled 99.2 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:ketol-acid reductoisomerase;
PDBTitle: crystal structure of class i acetohydroxy acid isomeroreductase from2 pseudomonas aeruginosa
92c1zejA_



not modelled 99.2 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-hydroxyacyl-coa dehydrogenase;
PDBTitle: crystal structure of the 3-hydroxyacyl-coa dehydrogenase (hbd-9,2 af2017) from archaeoglobus fulgidus dsm 4304 at 2.00 a resolution
93c3c24A_



not modelled 99.2 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of a putative oxidoreductase (yp_511008.1) from2 jannaschia sp. ccs1 at 1.62 a resolution
94d1guza1



not modelled 99.2 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
95c2vq3B_



not modelled 99.2 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:metalloreductase steap3;
PDBTitle: crystal structure of the membrane proximal oxidoreductase2 domain of human steap3, the dominant ferric reductase of3 the erythroid transferrin cycle
96d1uxja1



not modelled 99.2 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
97c1zcjA_



not modelled 99.2 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:peroxisomal bifunctional enzyme;
PDBTitle: crystal structure of 3-hydroxyacyl-coa dehydrogenase
98d1llda1



not modelled 99.2 25 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
99d5ldha1



not modelled 99.2 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
100d1i10a1



not modelled 99.2 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
101d1t2da1



not modelled 99.2 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
102d2pv7a2



not modelled 99.2 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
103c2i76B_



not modelled 99.2 19 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:hypothetical protein;
PDBTitle: crystal structure of protein tm1727 from thermotoga maritima
104d1ldna1



not modelled 99.1 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
105d2ldxa1



not modelled 99.1 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
106d1ldma1



not modelled 99.1 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
107c2rafC_



not modelled 99.1 11 PDB header:oxidoreductase
Chain: C: PDB Molecule:putative dinucleotide-binding oxidoreductase;
PDBTitle: crystal structure of putative dinucleotide-binding2 oxidoreductase (np_786167.1) from lactobacillus plantarum3 at 1.60 a resolution
108c2rcyB_



not modelled 99.1 12 PDB header:oxidoreductase
Chain: B: PDB Molecule:pyrroline carboxylate reductase;
PDBTitle: crystal structure of plasmodium falciparum pyrroline carboxylate2 reductase (mal13p1.284) with nadp bound
109c2x58B_



not modelled 99.1 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:peroxisomal bifunctional enzyme;
PDBTitle: the crystal structure of mfe1 liganded with coa
110c2d3tB_



not modelled 99.1 17 PDB header:lyase, oxidoreductase/transferase
Chain: B: PDB Molecule:fatty oxidation complex alpha subunit;
PDBTitle: fatty acid beta-oxidation multienzyme complex from2 pseudomonas fragi, form v
111d1ez4a1



not modelled 99.0 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
112d1pzga1



not modelled 99.0 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
113c2wtbA_



not modelled 99.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:fatty acid multifunctional protein (atmfp2);
PDBTitle: arabidopsis thaliana multifuctional protein, mfp2
114c2qytA_



not modelled 99.0 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-dehydropantoate 2-reductase;
PDBTitle: crystal structure of 2-dehydropantoate 2-reductase from porphyromonas2 gingivalis w83
115d2ahra2



not modelled 99.0 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
116c3c7cB_



not modelled 99.0 23 PDB header:oxidoreductase
Chain: B: PDB Molecule:octopine dehydrogenase;
PDBTitle: a structural basis for substrate and stereo selectivity in2 octopine dehydrogenase (odh-nadh-l-arginine)
117d1obba1



not modelled 99.0 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
118c1a5zA_



not modelled 98.9 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:l-lactate dehydrogenase;
PDBTitle: lactate dehydrogenase from thermotoga maritima (tmldh)
119c1hyhA_



not modelled 98.9 26 PDB header:oxidoreductase (choh(d)-nad+(a))
Chain: A: PDB Molecule:l-2-hydroxyisocaproate dehydrogenase;
PDBTitle: crystal structure of l-2-hydroxyisocaproate dehydrogenase from2 lactobacillus confusus at 2.2 angstroms resolution-an example of3 strong asymmetry between subunits
120c8ldhA_



not modelled 98.9 17 PDB header:oxidoreductase(choh(d)-nad(a))
Chain: A: PDB Molecule:m4 apo-lactate dehydrogenase;
PDBTitle: refined crystal structure of dogfish m4 apo-lactate2 dehydrogenase

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0