Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	I	I	Y	L	H	G	F	D	S	N	S	P	G	N	H	E	K	V	L	Q	L	Q	F	I	D	P	D	V	R	L	I	S	Y	S	T	R	H	P	K	H	D	M	Q	H	L	L	K	E	V	D	K	M	L	Q	L	N	V	D	E
Secondary structure
SS confidence
Disorder		?					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	P	L	I	C	G	V	G	L	G	G	Y	W	A	E	R	I	G	F	L	C	D	I	R	Q	V	I	F	N	P	N	L	F	P	Y	E	N	M	E	G	K	I	D	R	P	E	E	Y	A	D	I	A	T	K	C	V	T	N	F	R
Secondary structure
SS confidence
Disorder																																		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		E	K	N	R	D	R	C	L	V	I	L	S	R	N	D	E	A	L	N	S	Q	R	T	S	E	E	L	H	H	Y	Y	E	I	V	W	D	E	E	Q	T	H	K	F	K	N	I	S	P	H	L	Q	R	I	K	A	F	K	T	L	G
Secondary structure
SS confidence
Disorder																																																											?	?	?
Disorder confidence
Sequence
Secondary structure
SS confidence
Disorder
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1uxo chain A Region: 2 - 178 Aligned: 176 Modelled: 177 Confidence: 99.9% Identity: 10% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: YdeN-like Phyre2 PDB 2qs9 chain A Region: 2 - 177 Aligned: 170 Modelled: 176 Confidence: 99.9% Identity: 12% PDB header:structural protein Chain: A: PDB Molecule:retinoblastoma-binding protein 9; PDBTitle: crystal structure of the human retinoblastoma-binding2 protein 9 (rbbp-9). nesg target hr2978 Phyre2 PDB 2hu7 chain A Region: 1 - 177 Aligned: 177 Modelled: 177 Confidence: 99.9% Identity: 11% PDB header:hydrolase Chain: A: PDB Molecule:acylamino-acid-releasing enzyme; PDBTitle: binding of inhibitors by acylaminoacyl peptidase Phyre2 PDB 2qjw chain A Region: 2 - 177 Aligned: 157 Modelled: 157 Confidence: 99.9% Identity: 12% PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized protein xcc1541; PDBTitle: crystal structure of a putative hydrolase of the alpha/beta2 superfamily (xcc1541) from xanthomonas campestris pv. campestris at3 1.35 a resolution Phyre2 PDB 3llc chain A Region: 2 - 177 Aligned: 176 Modelled: 174 Confidence: 99.9% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of putative hydrolase (yp_002548124.1) from2 agrobacterium vitis s4 at 1.80 a resolution Phyre2 PDB 3azq chain A Region: 1 - 176 Aligned: 176 Modelled: 176 Confidence: 99.9% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:aminopeptidase; PDBTitle: crystal structure of puromycin hydrolase s511a mutant complexed with2 pgg Phyre2 PDB 1cr6 chain A Region: 2 - 177 Aligned: 174 Modelled: 175 Confidence: 99.9% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:epoxide hydrolase; PDBTitle: crystal structure of murine soluble epoxide hydrolase2 complexed with cpu inhibitor Phyre2 PDB 2ecf chain A Region: 1 - 177 Aligned: 177 Modelled: 177 Confidence: 99.9% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:dipeptidyl peptidase iv; PDBTitle: crystal structure of dipeptidyl aminopeptidase iv from2 stenotrophomonas maltophilia Phyre2 PDB 2y6v chain B Region: 2 - 178 Aligned: 175 Modelled: 177 Confidence: 99.9% Identity: 13% PDB header:hydrolase Chain: B: PDB Molecule:peroxisomal membrane protein lpx1; PDBTitle: peroxisomal alpha-beta-hydrolase lpx1 (yor084w) from2 saccharomyces cerevisiae (crystal form i) Phyre2 PDB 2g5t chain A Region: 1 - 177 Aligned: 177 Modelled: 177 Confidence: 99.8% Identity: 12% PDB header:hydrolase Chain: A: PDB Molecule:dipeptidyl peptidase 4; PDBTitle: crystal structure of human dipeptidyl peptidase iv (dppiv)2 complexed with cyanopyrrolidine (c5-pro-pro) inhibitor 21ag Phyre2 PDB 1z68 chain A Region: 1 - 177 Aligned: 177 Modelled: 177 Confidence: 99.8% Identity: 15% PDB header:lyase Chain: A: PDB Molecule:fibroblast activation protein, alpha subunit; PDBTitle: crystal structure of human fibroblast activation protein alpha Phyre2 PDB 1k8q chain A Region: 2 - 177 Aligned: 176 Modelled: 176 Confidence: 99.8% Identity: 16% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Gastric lipase Phyre2 PDB 3h04 chain A Region: 2 - 177 Aligned: 174 Modelled: 176 Confidence: 99.8% Identity: 16% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: the crystal structure of the protein with unknown function from2 staphylococcus aureus subsp. aureus mu50 Phyre2 PDB 2fuk chain A domain 1 Region: 1 - 178 Aligned: 158 Modelled: 158 Confidence: 99.8% Identity: 14% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Atu1826-like Phyre2 PDB 3bdv chain B Region: 2 - 177 Aligned: 159 Modelled: 162 Confidence: 99.8% Identity: 15% PDB header:hydrolase Chain: B: PDB Molecule:uncharacterized protein duf1234; PDBTitle: crystal structure of a putative yden-like hydrolase (eca3091) from2 pectobacterium atrosepticum scri1043 at 1.66 a resolution Phyre2 PDB 2vav chain L Region: 2 - 177 Aligned: 176 Modelled: 176 Confidence: 99.8% Identity: 13% PDB header:transferase Chain: L: PDB Molecule:acetyl-coa--deacetylcephalosporin c PDBTitle: crystal structure of deacetylcephalosporin c2 acetyltransferase (dac-soak) Phyre2 PDB 1hlg chain A Region: 2 - 177 Aligned: 176 Modelled: 176 Confidence: 99.8% Identity: 16% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Gastric lipase Phyre2 PDB 2wtm chain C Region: 2 - 178 Aligned: 177 Modelled: 177 Confidence: 99.8% Identity: 21% PDB header:hydrolase Chain: C: PDB Molecule:est1e; PDBTitle: est1e from butyrivibrio proteoclasticus Phyre2 PDB 2eep chain A Region: 1 - 176 Aligned: 176 Modelled: 176 Confidence: 99.8% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:dipeptidyl aminopeptidase iv, putative; PDBTitle: prolyl tripeptidyl aminopeptidase complexed with an inhibitor Phyre2 PDB 2b61 chain A domain 1 Region: 2 - 177 Aligned: 176 Modelled: 176 Confidence: 99.8% Identity: 13% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: O-acetyltransferase Phyre2 1 d1uxoa_ 2 c2qs9A_ 3 c2hu7A_ 4 c2qjwA_ 5 c3llcA_ 6 c3azqA_ 7 c1cr6A_ 8 c2ecfA_ 9 c2y6vB_ 10 c2g5tA_ 11 c1z68A_ 12 d1k8qa_ 13 c3h04A_ 14 d2fuka1 15 c3bdvB_ 16 c2vavL_ 17 d1hlga_ 18 c2wtmC_ 19 c2eepA_ 20 d2b61a1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1uxoa_ 99.9 10 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:YdeN-like 2 c2qs9A_ 99.9 12 PDB header:structural protein Chain: A: PDB Molecule:retinoblastoma-binding protein 9; PDBTitle: crystal structure of the human retinoblastoma-binding2 protein 9 (rbbp-9). nesg target hr2978 3 c2hu7A_ 99.9 11 PDB header:hydrolase Chain: A: PDB Molecule:acylamino-acid-releasing enzyme; PDBTitle: binding of inhibitors by acylaminoacyl peptidase 4 c2qjwA_ 99.9 12 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized protein xcc1541; PDBTitle: crystal structure of a putative hydrolase of the alpha/beta2 superfamily (xcc1541) from xanthomonas campestris pv. campestris at3 1.35 a resolution 5 c3llcA_ 99.9 18 PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of putative hydrolase (yp_002548124.1) from2 agrobacterium vitis s4 at 1.80 a resolution 6 c3azqA_ 99.9 16 PDB header:hydrolase Chain: A: PDB Molecule:aminopeptidase; PDBTitle: crystal structure of puromycin hydrolase s511a mutant complexed with2 pgg 7 c1cr6A_ 99.9 15 PDB header:hydrolase Chain: A: PDB Molecule:epoxide hydrolase; PDBTitle: crystal structure of murine soluble epoxide hydrolase2 complexed with cpu inhibitor 8 c2ecfA_ 99.9 16 PDB header:hydrolase Chain: A: PDB Molecule:dipeptidyl peptidase iv; PDBTitle: crystal structure of dipeptidyl aminopeptidase iv from2 stenotrophomonas maltophilia 9 c2y6vB_ 99.9 13 PDB header:hydrolase Chain: B: PDB Molecule:peroxisomal membrane protein lpx1; PDBTitle: peroxisomal alpha-beta-hydrolase lpx1 (yor084w) from2 saccharomyces cerevisiae (crystal form i) 10 c2g5tA_ 99.8 12 PDB header:hydrolase Chain: A: PDB Molecule:dipeptidyl peptidase 4; PDBTitle: crystal structure of human dipeptidyl peptidase iv (dppiv)2 complexed with cyanopyrrolidine (c5-pro-pro) inhibitor 21ag 11 c1z68A_ 99.8 15 PDB header:lyase Chain: A: PDB Molecule:fibroblast activation protein, alpha subunit; PDBTitle: crystal structure of human fibroblast activation protein alpha 12 d1k8qa_ 99.8 16 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Gastric lipase 13 c3h04A_ 99.8 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: the crystal structure of the protein with unknown function from2 staphylococcus aureus subsp. aureus mu50 14 d2fuka1 99.8 14 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Atu1826-like 15 c3bdvB_ 99.8 15 PDB header:hydrolase Chain: B: PDB Molecule:uncharacterized protein duf1234; PDBTitle: crystal structure of a putative yden-like hydrolase (eca3091) from2 pectobacterium atrosepticum scri1043 at 1.66 a resolution 16 c2vavL_ 99.8 13 PDB header:transferase Chain: L: PDB Molecule:acetyl-coa--deacetylcephalosporin c PDBTitle: crystal structure of deacetylcephalosporin c2 acetyltransferase (dac-soak) 17 d1hlga_ 99.8 16 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Gastric lipase 18 c2wtmC_ 99.8 21 PDB header:hydrolase Chain: C: PDB Molecule:est1e; PDBTitle: est1e from butyrivibrio proteoclasticus 19 c2eepA_ 99.8 13 PDB header:hydrolase Chain: A: PDB Molecule:dipeptidyl aminopeptidase iv, putative; PDBTitle: prolyl tripeptidyl aminopeptidase complexed with an inhibitor 20 d2b61a1 99.8 13 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:O-acetyltransferase 21 c2qtbB_ not modelled 99.8 12 PDB header:hydrolase Chain: B: PDB Molecule:dipeptidyl peptidase 4; PDBTitle: human dipeptidyl peptidase iv/cd26 in complex with a 4-aryl2 cyclohexylalanine inhibitor 22 c3v48B_ not modelled 99.8 13 PDB header:hydrolase Chain: B: PDB Molecule:putative aminoacrylate hydrolase rutd; PDBTitle: crystal structure of the putative alpha/beta hydrolase rutd from2 e.coli 23 d2vata1 not modelled 99.8 14 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:O-acetyltransferase 24 c3ksrA_ not modelled 99.8 10 PDB header:hydrolase Chain: A: PDB Molecule:putative serine hydrolase; PDBTitle: crystal structure of a putative serine hydrolase (xcc3885) from2 xanthomonas campestris pv. campestris at 2.69 a resolution 25 c2q0xA_ not modelled 99.8 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: alpha/beta hydrolase fold protein of unknown function 26 c3i1iA_ not modelled 99.8 18 PDB header:transferase Chain: A: PDB Molecule:homoserine o-acetyltransferase; PDBTitle: x-ray crystal structure of homoserine o-acetyltransferase from2 bacillus anthracis 27 c2r11D_ not modelled 99.8 14 PDB header:hydrolase Chain: D: PDB Molecule:carboxylesterase np; PDBTitle: crystal structure of putative hydrolase (2632844) from2 bacillus subtilis at 1.96 a resolution 28 d1ufoa_ not modelled 99.8 14 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Hypothetical protein TT1662 29 c3dyvA_ not modelled 99.8 11 PDB header:hydrolase Chain: A: PDB Molecule:esterase d; PDBTitle: snapshots of esterase d from lactobacillus rhamnosus:2 insights into a rotation driven catalytic mechanism 30 c3qvmA_ not modelled 99.8 13 PDB header:hydrolase Chain: A: PDB Molecule:olei00960; PDBTitle: the structure of olei00960, a hydrolase from oleispira antarctica 31 c1xfdD_ not modelled 99.8 15 PDB header:membrane protein Chain: D: PDB Molecule:dipeptidyl aminopeptidase-like protein 6; PDBTitle: structure of a human a-type potassium channel accelerating factor2 dppx, a member of the dipeptidyl aminopeptidase family 32 c3fnbB_ not modelled 99.8 12 PDB header:hydrolase Chain: B: PDB Molecule:acylaminoacyl peptidase smu_737; PDBTitle: crystal structure of acylaminoacyl peptidase smu_737 from2 streptococcus mutans ua159 33 c2qmqA_ not modelled 99.8 11 PDB header:signaling protein Chain: A: PDB Molecule:protein ndrg2; PDBTitle: crystal structure of a n-myc downstream regulated 2 protein (ndrg2,2 syld, ndr2, ai182517, au040374) from mus musculus at 1.70 a3 resolution 34 c3fleB_ not modelled 99.8 11 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:se_1780 protein; PDBTitle: se_1780 protein of unknown function from staphylococcus epidermidis. 35 c2qruA_ not modelled 99.8 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an alpha/beta hydrolase superfamily protein from2 enterococcus faecalis 36 c3trdA_ not modelled 99.8 12 PDB header:hydrolase Chain: A: PDB Molecule:alpha/beta hydrolase; PDBTitle: structure of an alpha-beta serine hydrolase homologue from coxiella2 burnetii 37 c3oosA_ not modelled 99.8 12 PDB header:hydrolase Chain: A: PDB Molecule:alpha/beta hydrolase family protein; PDBTitle: the structure of an alpha/beta fold family hydrolase from bacillus2 anthracis str. sterne 38 d2jbwa1 not modelled 99.8 12 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:2,6-dihydropseudooxynicotine hydrolase-like 39 d2pl5a1 not modelled 99.8 15 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:O-acetyltransferase 40 c2o2gA_ not modelled 99.8 11 PDB header:hydrolase Chain: A: PDB Molecule:dienelactone hydrolase; PDBTitle: crystal structure of dienelactone hydrolase (yp_324580.1) from2 anabaena variabilis atcc 29413 at 1.92 a resolution 41 c2jbwB_ not modelled 99.8 12 PDB header:hydrolase Chain: B: PDB Molecule:2,6-dihydroxy-pseudo-oxynicotine hydrolase; PDBTitle: crystal structure of the 2,6-dihydroxy-pseudo-oxynicotine2 hydrolase. 42 c3e0xB_ not modelled 99.8 11 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:lipase-esterase related protein; PDBTitle: the crystal structure of a lipase-esterase related protein2 from clostridium acetobutylicum atcc 824 43 c3om8A_ not modelled 99.8 15 PDB header:hydrolase Chain: A: PDB Molecule:probable hydrolase; PDBTitle: the crystal structure of a hydrolase from pseudomonas aeruginosa pa01 44 c3fsgC_ not modelled 99.8 17 PDB header:hydrolase Chain: C: PDB Molecule:alpha/beta superfamily hydrolase; PDBTitle: crystal structure of alpha/beta superfamily hydrolase from oenococcus2 oeni psu-1 45 c3hlkB_ not modelled 99.7 13 PDB header:hydrolase Chain: B: PDB Molecule:acyl-coenzyme a thioesterase 2, mitochondrial; PDBTitle: crystal structure of human mitochondrial acyl-coa2 thioesterase (acot2) 46 c3qm1A_ not modelled 99.7 11 PDB header:hydrolase Chain: A: PDB Molecule:cinnamoyl esterase; PDBTitle: crystal structure of the lactobacillus johnsonii cinnamoyl esterase2 lj0536 s106a mutant in complex with ethylferulate, form ii 47 c3flaB_ not modelled 99.7 10 PDB header:hydrolase Chain: B: PDB Molecule:rifr; PDBTitle: rifr - type ii thioesterase from rifamycin nrps/pks biosynthetic2 pathway - form 1 48 c3lp5A_ not modelled 99.7 9 PDB header:hydrolase Chain: A: PDB Molecule:putative cell surface hydrolase; PDBTitle: the crystal structure of the putative cell surface hydrolase from2 lactobacillus plantarum wcfs1 49 c2i3dA_ not modelled 99.7 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein atu1826; PDBTitle: crystal structure of protein of unknown function atu1826, a putative2 alpha/beta hydrolase from agrobacterium tumefaciens 50 d2i3da1 not modelled 99.7 13 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Atu1826-like 51 c2yysA_ not modelled 99.7 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:proline iminopeptidase-related protein; PDBTitle: crystal structure of the proline iminopeptidase-related protein2 ttha1809 from thermus thermophilus hb8 52 c3mveB_ not modelled 99.7 16 PDB header:lyase Chain: B: PDB Molecule:upf0255 protein vv1_0328; PDBTitle: crystal structure of a novel pyruvate decarboxylase 53 c1ycdA_ not modelled 99.7 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical 27.3 kda protein in aap1-smf2 PDBTitle: crystal structure of yeast fsh1/yhr049w, a member of the2 serine hydrolase family 54 c3k2iA_ not modelled 99.7 14 PDB header:hydrolase Chain: A: PDB Molecule:acyl-coenzyme a thioesterase 4; PDBTitle: human acyl-coenzyme a thioesterase 4 55 d1b6ga_ not modelled 99.7 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloalkane dehalogenase 56 c3l80A_ not modelled 99.7 13 PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein smu.1393c; PDBTitle: crystal structure of smu.1393c from streptococcus mutans ua159 57 c3jw8A_ not modelled 99.7 16 PDB header:hydrolase Chain: A: PDB Molecule:mgll protein; PDBTitle: crystal structure of human mono-glyceride lipase 58 c2cjpA_ not modelled 99.7 16 PDB header:hydrolase Chain: A: PDB Molecule:epoxide hydrolase; PDBTitle: structure of potato (solanum tuberosum) epoxide hydrolase i2 (steh1) 59 c2bklB_ not modelled 99.7 14 PDB header:hydrolase Chain: B: PDB Molecule:prolyl endopeptidase; PDBTitle: structural and mechanistic analysis of two prolyl2 endopeptidases: role of inter-domain dynamics in3 catalysis and specificity 60 d2r8ba1 not modelled 99.7 14 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase/thioesterase 1 61 d1imja_ not modelled 99.7 10 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Ccg1/TafII250-interacting factor B (Cib) 62 c2xuaH_ not modelled 99.7 16 PDB header:hydrolase Chain: H: PDB Molecule:3-oxoadipate enol-lactonase; PDBTitle: crystal structure of the enol-lactonase from burkholderia2 xenovorans lb400 63 d1pjaa_ not modelled 99.7 11 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Thioesterases 64 c1pjaA_ not modelled 99.7 11 PDB header:hydrolase Chain: A: PDB Molecule:palmitoyl-protein thioesterase 2 precursor; PDBTitle: the crystal structure of palmitoyl protein thioesterase-2 reveals the2 basis for divergent substrate specificities of the two lysosomal3 thioesterases (ppt1 and ppt2) 65 d1vkha_ not modelled 99.7 14 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Putative serine hydrolase Ydr428c 66 c3bxpA_ not modelled 99.7 9 PDB header:hydrolase Chain: A: PDB Molecule:putative lipase/esterase; PDBTitle: crystal structure of a putative carboxylesterase (lp_2923) from2 lactobacillus plantarum wcfs1 at 1.70 a resolution 67 c3i6yA_ not modelled 99.7 15 PDB header:hydrolase Chain: A: PDB Molecule:esterase apc40077; PDBTitle: structure of an esterase from the oil-degrading bacterium oleispira2 antarctica 68 c2e3jA_ not modelled 99.7 17 PDB header:hydrolase Chain: A: PDB Molecule:epoxide hydrolase ephb; PDBTitle: the crystal structure of epoxide hydrolase b (rv1938) from2 mycobacterium tuberculosis at 2.1 angstrom 69 d1wm1a_ not modelled 99.7 16 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Proline iminopeptidase-like 70 c3bjrA_ not modelled 99.7 10 PDB header:hydrolase Chain: A: PDB Molecule:putative carboxylesterase; PDBTitle: crystal structure of a putative carboxylesterase (lp_1002) from2 lactobacillus plantarum wcfs1 at 2.09 a resolution 71 c3ds8A_ not modelled 99.7 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:lin2722 protein; PDBTitle: the crysatl structure of the gene lin2722 products from listeria2 innocua 72 c3fcxA_ not modelled 99.7 15 PDB header:hydrolase Chain: A: PDB Molecule:s-formylglutathione hydrolase; PDBTitle: crystal structure of human esterase d 73 c2r8bA_ not modelled 99.7 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein atu2452; PDBTitle: the crystal structure of the protein atu2452 of unknown function from2 agrobacterium tumefaciens str. c58 74 d1ispa_ not modelled 99.7 13 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Bacterial lipase 75 d1azwa_ not modelled 99.7 14 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Proline iminopeptidase-like 76 c3hjuB_ not modelled 99.7 17 PDB header:hydrolase Chain: B: PDB Molecule:monoglyceride lipase; PDBTitle: crystal structure of human monoglyceride lipase 77 c2xt0A_ not modelled 99.7 21 PDB header:hydrolase Chain: A: PDB Molecule:haloalkane dehalogenase; PDBTitle: dehalogenase dppa from plesiocystis pacifica sir-i 78 c3e3aA_ not modelled 99.7 14 PDB header:oxidoreductase Chain: A: PDB Molecule:possible peroxidase bpoc; PDBTitle: the structure of rv0554 from mycobacterium tuberculosis 79 c3qmwD_ not modelled 99.7 13 PDB header:hydrolase Chain: D: PDB Molecule:thioesterase; PDBTitle: redj with peg molecule bound in the active site 80 d1tqha_ not modelled 99.7 18 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase/lipase 81 c1qfmA_ not modelled 99.7 14 PDB header:hydrolase Chain: A: PDB Molecule:protein (prolyl oligopeptidase); PDBTitle: prolyl oligopeptidase from porcine muscle 82 d1l7aa_ not modelled 99.7 19 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Acetyl xylan esterase-like 83 c2zshA_ not modelled 99.7 16 PDB header:hormone receptor Chain: A: PDB Molecule:probable gibberellin receptor gid1l1; PDBTitle: structural basis of gibberellin(ga3)-induced della2 recognition by the gibberellin receptor 84 d1mtza_ not modelled 99.7 11 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Proline iminopeptidase-like 85 d1ex9a_ not modelled 99.7 12 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Bacterial lipase 86 c3d7rB_ not modelled 99.7 15 PDB header:hydrolase Chain: B: PDB Molecule:esterase; PDBTitle: crystal structure of a putative esterase from staphylococcus aureus 87 d1c4xa_ not modelled 99.7 14 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carbon-carbon bond hydrolase 88 d1m33a_ not modelled 99.7 12 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Biotin biosynthesis protein BioH 89 c3iumA_ not modelled 99.7 10 PDB header:hydrolase Chain: A: PDB Molecule:prolyl endopeptidase; PDBTitle: appep_wtx opened state 90 c3e4dD_ not modelled 99.7 15 PDB header:hydrolase Chain: D: PDB Molecule:esterase d; PDBTitle: structural and kinetic study of an s-formylglutathione2 hydrolase from agrobacterium tumefaciens 91 c3ls2D_ not modelled 99.7 16 PDB header:hydrolase Chain: D: PDB Molecule:s-formylglutathione hydrolase; PDBTitle: crystal structure of an s-formylglutathione hydrolase from2 pseudoalteromonas haloplanktis tac125 92 d2hu7a2 not modelled 99.7 10 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Acylamino-acid-releasing enzyme, C-terminal donain 93 c3bdiA_ not modelled 99.7 16 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized protein ta0194; PDBTitle: crystal structure of predicted cib-like hydrolase (np_393672.1) from2 thermoplasma acidophilum at 1.45 a resolution 94 d1fj2a_ not modelled 99.6 14 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase/thioesterase 1 95 d1ehya_ not modelled 99.6 16 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Epoxide hydrolase 96 c2xe4A_ not modelled 99.6 14 PDB header:hydrolase/inhibitor Chain: A: PDB Molecule:oligopeptidase b; PDBTitle: structure of oligopeptidase b from leishmania major 97 d1zd3a2 not modelled 99.6 15 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Epoxide hydrolase 98 c2o7vA_ not modelled 99.6 17 PDB header:hydrolase Chain: A: PDB Molecule:cxe carboxylesterase; PDBTitle: carboxylesterase aecxe1 from actinidia eriantha covalently inhibited2 by paraoxon 99 d3c70a1 not modelled 99.6 10 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Hydroxynitrile lyase-like 100 d1hkha_ not modelled 99.6 15 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloperoxidase 101 c3bwxA_ not modelled 99.6 18 PDB header:hydrolase Chain: A: PDB Molecule:alpha/beta hydrolase; PDBTitle: crystal structure of an alpha/beta hydrolase (yp_496220.1) from2 novosphingobium aromaticivorans dsm 12444 at 1.50 a resolution 102 c1y37A_ not modelled 99.6 13 PDB header:hydrolase Chain: A: PDB Molecule:fluoroacetate dehalogenase; PDBTitle: structure of fluoroacetate dehalogenase from burkholderia sp. fa1 103 c3og9A_ not modelled 99.6 13 PDB header:hydrolase Chain: A: PDB Molecule:protein yahd a copper inducible hydrolase; PDBTitle: structure of yahd with malic acid 104 d1e89a_ not modelled 99.6 11 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Hydroxynitrile lyase-like 105 d1cr6a2 not modelled 99.6 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Epoxide hydrolase 106 c1zoiC_ not modelled 99.6 16 PDB header:hydrolase Chain: C: PDB Molecule:esterase; PDBTitle: crystal structure of a stereoselective esterase from2 pseudomonas putida ifo12996 107 d2h1ia1 not modelled 99.6 15 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase/thioesterase 1 108 c3kxpD_ not modelled 99.6 14 PDB header:hydrolase Chain: D: PDB Molecule:alpha-(n-acetylaminomethylene)succinic acid PDBTitle: crystal structure of e-2-(acetamidomethylene)succinate2 hydrolase 109 c2hdwB_ not modelled 99.6 12 PDB header:hydrolase Chain: B: PDB Molecule:hypothetical protein pa2218; PDBTitle: crystal structure of hypothetical protein pa2218 from pseudomonas2 aeruginosa 110 c3p2mA_ not modelled 99.6 13 PDB header:hydrolase Chain: A: PDB Molecule:possible hydrolase; PDBTitle: crystal structure of a novel esterase rv0045c from mycobacterium2 tuberculosis 111 c3doiA_ not modelled 99.6 14 PDB header:hydrolase Chain: A: PDB Molecule:esterase; PDBTitle: crystal structure of a thermostable esterase complex with2 paraoxon 112 c3u0vA_ not modelled 99.6 17 PDB header:hydrolase Chain: A: PDB Molecule:lysophospholipase-like protein 1; PDBTitle: crystal structure analysis of human lyplal1 113 d1pv1a_ not modelled 99.6 19 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Hypothetical esterase YJL068C 114 c2h1iA_ not modelled 99.6 11 PDB header:hydrolase Chain: A: PDB Molecule:carboxylesterase; PDBTitle: crystal structure of the bacillus cereus carboxylesterase 115 d1jfra_ not modelled 99.6 12 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Lipase 116 c3r0vA_ not modelled 99.6 18 PDB header:hydrolase Chain: A: PDB Molecule:alpha/beta hydrolase fold protein; PDBTitle: the crystal structure of an alpha/beta hydrolase from sphaerobacter2 thermophilus dsm 20745. 117 d1qfma2 not modelled 99.6 11 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Prolyl oligopeptidase, C-terminal domain 118 c3dqzB_ not modelled 99.6 13 PDB header:lyase Chain: B: PDB Molecule:alpha-hydroxynitrile lyase-like protein; PDBTitle: structure of the hydroxynitrile lyase from arabidopsis2 thaliana 119 c1u2eA_ not modelled 99.6 16 PDB header:hydrolase Chain: A: PDB Molecule:2-hydroxy-6-ketonona-2,4-dienedioic acid PDBTitle: crystal structure of the c-c bond hydrolase mhpc 120 c1yr2A_ not modelled 99.6 11 PDB header:hydrolase Chain: A: PDB Molecule:prolyl oligopeptidase; PDBTitle: structural and mechanistic analysis of two prolyl endopeptidases: role2 of inter-domain dynamics in catalysis and specificity

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0