Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	V	F	N	K	F	A	R	T	F	K	S	H	W	L	L	Y	L	C	V	I	V	F	G	I	T	N	L	V	A	S	S	G	A	H	M	V	Q	R	L	L	F	F	V	L	T	I	L	V	V	K	R	I	S	S	L	P	L	R
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	L	V	A	A	P	F	V	L	L	T	A	A	D	M	S	I	S	L	Y	S	W	C	T	F	G	T	T	F	N	D	G	F	A	I	S	V	L	Q	S	D	P	D	E	V	V	K	M	L	G	M	Y	I	P	Y	L	C	A	F	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		F	L	S	L	L	F	L	A	V	I	I	K	Y	D	V	S	L	P	T	K	K	V	T	G	I	L	L	L	I	V	I	S	G	S	L	F	S	A	C	Q	F	A	Y	K	D	A	K	N	K	K	A	F	S	P	Y	I	L	A	S	R
Secondary structure
SS confidence
Disorder														?	?	?	?	?	?	?	?	?																					?	?	?	?	?	?	?	?	?		?	?	?	?	?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		F	A	T	Y	T	P	F	F	N	L	N	Y	F	A	L	A	A	K	E	H	Q	R	L	L	S	I	A	N	T	V	P	Y	F	Q	L	S	V	R	D	T	G	I	D	T	Y	V	L	I	V	G	E	S	V	R	V	D	N	M	S	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?			?						?	?	?							?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		Y	G	Y	T	R	S	T	T	P	Q	V	E	A	Q	R	K	Q	I	K	L	F	N	Q	A	I	S	G	A	P	Y	T	A	L	S	V	P	L	S	L	T	A	D	S	V	L	S	H	D	I	H	N	Y	P	D	N	I	I	N	M	A
Secondary structure
SS confidence
Disorder																	?																							?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		N	Q	A	G	F	Q	T	F	W	L	S	S	Q	S	A	F	R	Q	N	G	T	A	V	T	S	I	A	M	R	A	M	E	T	V	Y	V	R	G	F	D	E	L	L	L	P	H	L	S	Q	A	L	Q	Q	N	T	Q	Q	K	K	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		I	V	L	H	L	N	G	S	H	E	P	A	C	S	A	Y	P	Q	S	S	A	V	F	Q	P	Q	D	D	Q	D	A	C	Y	D	N	S	I	H	Y	T	D	S	L	L	G	Q	V	F	E	L	L	K	D	R	R	A	S	V	M	Y
Secondary structure
SS confidence
Disorder																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		F	A	D	H	G	L	E	R	D	P	T	K	K	N	V	Y	F	H	G	G	R	E	A	S	Q	Q	A	Y	H	V	P	M	F	I	W	Y	S	P	V	L	G	D	G	V	D	R	T	T	E	N	N	I	F	S	T	A	Y	N	N	Y
Secondary structure
SS confidence
Disorder									?	?	?	?	?	?							?		?																?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		L	I	N	A	W	M	G	V	T	K	P	E	Q	P	Q	T	L	E	E	V	I	A	H	Y	K	G	D	S	R	V	V	D	A	N	H	D	V	F	D	Y	V	M	L	R	K	E	F	T	E	D	K	Q	G	N	P	T	P	E	G	Q
Secondary structure
SS confidence
Disorder														?	?	?																																			?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.
Sequence		G
Secondary structure
SS confidence
Disorder		?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2w8d chain B Region: 194 - 540 Aligned: 341 Modelled: 346 Confidence: 100.0% Identity: 13% PDB header:transferase Chain: B: PDB Molecule:processed glycerol phosphate lipoteichoic acid synthase 2; PDBTitle: distinct and essential morphogenic functions for wall- and2 lipo-teichoic acids in bacillus subtilis Phyre2 PDB 3ed4 chain A Region: 222 - 537 Aligned: 312 Modelled: 315 Confidence: 100.0% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:arylsulfatase; PDBTitle: crystal structure of putative arylsulfatase from escherichia coli Phyre2 PDB 1fsu chain A Region: 220 - 537 Aligned: 312 Modelled: 318 Confidence: 100.0% Identity: 12% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 2qzu chain A Region: 217 - 500 Aligned: 277 Modelled: 284 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of the putative sulfatase yidj from bacteroides2 fragilis. northeast structural genomics consortium target bfr123 Phyre2 PDB 2w5t chain A Region: 200 - 540 Aligned: 335 Modelled: 341 Confidence: 100.0% Identity: 11% PDB header:transferase Chain: A: PDB Molecule:processed glycerol phosphate lipoteichoic acid PDBTitle: structure-based mechanism of lipoteichoic acid synthesis by2 staphylococcus aureus ltas. Phyre2 PDB 3b5q chain B Region: 221 - 538 Aligned: 314 Modelled: 316 Confidence: 100.0% Identity: 14% PDB header:hydrolase Chain: B: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of a putative sulfatase (np_810509.1)2 from bacteroides thetaiotaomicron vpi-5482 at 2.40 a3 resolution Phyre2 PDB 3lxq chain B Region: 177 - 520 Aligned: 325 Modelled: 344 Confidence: 100.0% Identity: 14% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein vp1736; PDBTitle: the crystal structure of a protein in the alkaline2 phosphatase superfamily from vibrio parahaemolyticus to3 1.95a Phyre2 PDB 1auk chain A Region: 221 - 500 Aligned: 269 Modelled: 280 Confidence: 100.0% Identity: 14% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 1hdh chain A Region: 221 - 493 Aligned: 265 Modelled: 273 Confidence: 100.0% Identity: 17% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 1p49 chain A Region: 219 - 501 Aligned: 273 Modelled: 277 Confidence: 100.0% Identity: 16% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 2vqr chain A Region: 222 - 500 Aligned: 273 Modelled: 277 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase; PDBTitle: crystal structure of a phosphonate monoester hydrolase2 from rhizobium leguminosarum: a new member of the3 alkaline phosphatase superfamily Phyre2 PDB 1o98 chain A domain 2 Region: 222 - 500 Aligned: 252 Modelled: 266 Confidence: 100.0% Identity: 13% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, catalytic domain Phyre2 PDB 2zkt chain B Region: 222 - 490 Aligned: 257 Modelled: 268 Confidence: 100.0% Identity: 13% PDB header:isomerase Chain: B: PDB Molecule:2,3-bisphosphoglycerate-independent phosphoglycerate PDBTitle: structure of ph0037 protein from pyrococcus horikoshii Phyre2 PDB 3m8y chain C Region: 221 - 500 Aligned: 245 Modelled: 263 Confidence: 100.0% Identity: 16% PDB header:isomerase Chain: C: PDB Molecule:phosphopentomutase; PDBTitle: phosphopentomutase from bacillus cereus after glucose-1,6-bisphosphate2 activation Phyre2 PDB 2i09 chain A domain 1 Region: 220 - 500 Aligned: 236 Modelled: 259 Confidence: 100.0% Identity: 12% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: DeoB catalytic domain-like Phyre2 PDB 2gso chain B Region: 222 - 502 Aligned: 255 Modelled: 265 Confidence: 99.9% Identity: 17% PDB header:hydrolase Chain: B: PDB Molecule:phosphodiesterase-nucleotide pyrophosphatase; PDBTitle: structure of xac nucleotide2 pyrophosphatase/phosphodiesterase in complex with vanadate Phyre2 PDB 3q3q chain A Region: 213 - 499 Aligned: 269 Modelled: 287 Confidence: 99.9% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:alkaline phosphatase; PDBTitle: crystal structure of spap: an novel alkaline phosphatase from2 bacterium sphingomonas sp. strain bsar-1 Phyre2 PDB 2i09 chain A Region: 220 - 500 Aligned: 243 Modelled: 267 Confidence: 99.9% Identity: 14% PDB header:isomerase Chain: A: PDB Molecule:phosphopentomutase; PDBTitle: crystal structure of putative phosphopentomutase from streptococcus2 mutans Phyre2 PDB 3szz chain A Region: 214 - 483 Aligned: 251 Modelled: 251 Confidence: 99.9% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:phosphonoacetate hydrolase; PDBTitle: crystal structure of phosphonoacetate hydrolase from sinorhizobium2 meliloti 1021 in complex with acetate Phyre2 PDB 1ei6 chain A Region: 221 - 483 Aligned: 242 Modelled: 250 Confidence: 99.9% Identity: 12% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Phosphonoacetate hydrolase Phyre2 1 c2w8dB_ 2 c3ed4A_ 3 d1fsua_ 4 c2qzuA_ 5 c2w5tA_ 6 c3b5qB_ 7 c3lxqB_ 8 d1auka_ 9 d1hdha_ 10 d1p49a_ 11 c2vqrA_ 12 d1o98a2 13 c2zktB_ 14 c3m8yC_ 15 d2i09a1 16 c2gsoB_ 17 c3q3qA_ 18 c2i09A_ 19 c3szzA_ 20 d1ei6a_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2w8dB_ 100.0 13 PDB header:transferase Chain: B: PDB Molecule:processed glycerol phosphate lipoteichoic acid synthase 2; PDBTitle: distinct and essential morphogenic functions for wall- and2 lipo-teichoic acids in bacillus subtilis 2 c3ed4A_ 100.0 16 PDB header:transferase Chain: A: PDB Molecule:arylsulfatase; PDBTitle: crystal structure of putative arylsulfatase from escherichia coli 3 d1fsua_ 100.0 12 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 4 c2qzuA_ 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of the putative sulfatase yidj from bacteroides2 fragilis. northeast structural genomics consortium target bfr123 5 c2w5tA_ 100.0 11 PDB header:transferase Chain: A: PDB Molecule:processed glycerol phosphate lipoteichoic acid PDBTitle: structure-based mechanism of lipoteichoic acid synthesis by2 staphylococcus aureus ltas. 6 c3b5qB_ 100.0 14 PDB header:hydrolase Chain: B: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of a putative sulfatase (np_810509.1)2 from bacteroides thetaiotaomicron vpi-5482 at 2.40 a3 resolution 7 c3lxqB_ 100.0 14 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein vp1736; PDBTitle: the crystal structure of a protein in the alkaline2 phosphatase superfamily from vibrio parahaemolyticus to3 1.95a 8 d1auka_ 100.0 14 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 9 d1hdha_ 100.0 17 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 10 d1p49a_ 100.0 16 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 11 c2vqrA_ 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase; PDBTitle: crystal structure of a phosphonate monoester hydrolase2 from rhizobium leguminosarum: a new member of the3 alkaline phosphatase superfamily 12 d1o98a2 100.0 13 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, catalytic domain 13 c2zktB_ 100.0 13 PDB header:isomerase Chain: B: PDB Molecule:2,3-bisphosphoglycerate-independent phosphoglycerate PDBTitle: structure of ph0037 protein from pyrococcus horikoshii 14 c3m8yC_ 100.0 16 PDB header:isomerase Chain: C: PDB Molecule:phosphopentomutase; PDBTitle: phosphopentomutase from bacillus cereus after glucose-1,6-bisphosphate2 activation 15 d2i09a1 100.0 12 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:DeoB catalytic domain-like 16 c2gsoB_ 99.9 17 PDB header:hydrolase Chain: B: PDB Molecule:phosphodiesterase-nucleotide pyrophosphatase; PDBTitle: structure of xac nucleotide2 pyrophosphatase/phosphodiesterase in complex with vanadate 17 c3q3qA_ 99.9 22 PDB header:hydrolase Chain: A: PDB Molecule:alkaline phosphatase; PDBTitle: crystal structure of spap: an novel alkaline phosphatase from2 bacterium sphingomonas sp. strain bsar-1 18 c2i09A_ 99.9 14 PDB header:isomerase Chain: A: PDB Molecule:phosphopentomutase; PDBTitle: crystal structure of putative phosphopentomutase from streptococcus2 mutans 19 c3szzA_ 99.9 14 PDB header:hydrolase Chain: A: PDB Molecule:phosphonoacetate hydrolase; PDBTitle: crystal structure of phosphonoacetate hydrolase from sinorhizobium2 meliloti 1021 in complex with acetate 20 d1ei6a_ 99.9 12 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Phosphonoacetate hydrolase 21 c2xrgA_ not modelled 99.9 16 PDB header:hydrolase Chain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) in complex with the2 ha155 boronic acid inhibitor 22 c2xr9A_ not modelled 99.9 15 PDB header:hydrolase Chain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) 23 c1o98A_ not modelled 99.6 13 PDB header:isomerase Chain: A: PDB Molecule:2,3-bisphosphoglycerate-independent PDBTitle: 1.4a crystal structure of phosphoglycerate mutase from2 bacillus stearothermophilus complexed with3 2-phosphoglycerate 24 c3igzB_ not modelled 99.6 15 PDB header:isomerase Chain: B: PDB Molecule:cofactor-independent phosphoglycerate mutase; PDBTitle: crystal structures of leishmania mexicana phosphoglycerate2 mutase at low cobalt concentration 25 c2d1gB_ not modelled 99.4 18 PDB header:hydrolase Chain: B: PDB Molecule:acid phosphatase; PDBTitle: structure of francisella tularensis acid phosphatase a (acpa) bound to2 orthovanadate 26 c2iucB_ not modelled 98.9 16 PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: structure of alkaline phosphatase from the antarctic2 bacterium tab5 27 d1y6va1 not modelled 98.5 18 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Alkaline phosphatase 28 c1ew2A_ not modelled 98.4 14 PDB header:hydrolase Chain: A: PDB Molecule:phosphatase; PDBTitle: crystal structure of a human phosphatase 29 c2w0yB_ not modelled 98.4 10 PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: h.salinarum alkaline phosphatase 30 d1zeda1 not modelled 98.4 14 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Alkaline phosphatase 31 d1k7ha_ not modelled 98.4 13 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Alkaline phosphatase 32 c2x98A_ not modelled 98.3 13 PDB header:hydrolase Chain: A: PDB Molecule:alkaline phosphatase; PDBTitle: h.salinarum alkaline phosphatase 33 c3a52A_ not modelled 98.1 14 PDB header:hydrolase Chain: A: PDB Molecule:cold-active alkaline phosphatase; PDBTitle: crystal structure of cold-active alkailne phosphatase from2 psychrophile shewanella sp. 34 c3e2dB_ not modelled 98.0 19 PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: the 1.4 a crystal structure of the large and cold-active2 vibrio sp. alkaline phosphatase 35 c3iddA_ not modelled 87.8 20 PDB header:isomerase Chain: A: PDB Molecule:2,3-bisphosphoglycerate-independent PDBTitle: cofactor-independent phosphoglycerate mutase from2 thermoplasma acidophilum dsm 1728 36 c3bijC_ not modelled 63.4 15 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:uncharacterized protein gsu0716; PDBTitle: crystal structure of protein gsu0716 from geobacter2 sulfurreducens. northeast structural genomics target gsr13 37 c3uoaB_ not modelled 58.2 21 PDB header:hydrolase/hydrolase inhibitor Chain: B: PDB Molecule:mucosa-associated lymphoid tissue lymphoma translocation PDBTitle: crystal structure of the malt1 paracaspase (p21 form) 38 d1b4ub_ not modelled 56.5 9 Fold:Phosphorylase/hydrolase-like Superfamily:LigB-like Family:LigB-like 39 d2nxfa1 not modelled 43.8 12 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:ADPRibase-Mn-like 40 d1s1qa_ not modelled 32.7 14 Fold:UBC-like Superfamily:UBC-like Family:UEV domain 41 d1qnra_ not modelled 31.1 8 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-glycanases 42 d1j33a_ not modelled 29.1 54 Fold:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) Superfamily:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) Family:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) 43 d1l5oa_ not modelled 28.3 38 Fold:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) Superfamily:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) Family:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) 44 d1cmwa2 not modelled 20.0 8 Fold:PIN domain-like Superfamily:PIN domain-like Family:5' to 3' exonuclease catalytic domain 45 c2jcmA_ not modelled 15.5 24 PDB header:hydrolase Chain: A: PDB Molecule:cytosolic purine 5'-nucleotidase; PDBTitle: crystal structure of human cytosolic 5'-nucleotidase ii in2 complex with beryllium trifluoride 46 d1ma3a_ not modelled 12.6 13 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 47 d2bdea1 not modelled 11.3 24 Fold:HAD-like Superfamily:HAD-like Family:5' nucleotidase-like 48 d1txla_ not modelled 10.2 15 Fold:Lipocalins Superfamily:Lipocalins Family:Hypothetical protein YodA 49 c1txlA_ not modelled 10.2 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:metal-binding protein yoda; PDBTitle: crystal structure of metal-binding protein yoda from e.2 coli, pfam duf149 50 d2hy1a1 not modelled 10.1 27 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:GpdQ-like 51 c2hy1A_ not modelled 10.1 27 PDB header:hydrolase Chain: A: PDB Molecule:rv0805; PDBTitle: crystal structure of rv0805 52 d1yj5a1 not modelled 10.0 11 Fold:HAD-like Superfamily:HAD-like Family:phosphatase domain of polynucleotide kinase 53 c3t1iC_ not modelled 10.0 10 PDB header:hydrolase Chain: C: PDB Molecule:double-strand break repair protein mre11a; PDBTitle: crystal structure of human mre11: understanding tumorigenic mutations 54 d2r7ka1 not modelled 10.0 18 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:PurP N-terminal domain-like 55 c3ib7A_ not modelled 9.9 26 PDB header:hydrolase Chain: A: PDB Molecule:icc protein; PDBTitle: crystal structure of full length rv0805 56 c2xokG_ not modelled 9.4 19 PDB header:hydrolase Chain: G: PDB Molecule:atp synthase subunit gamma, mitochondrial; PDBTitle: refined structure of yeast f1c10 atpase complex to 3 a2 resolution 57 c2funB_ not modelled 9.4 12 PDB header:apoptosis/hydrolase Chain: B: PDB Molecule:caspase-8; PDBTitle: alternative p35-caspase-8 complex 58 c3oaaO_ not modelled 9.3 20 PDB header:hydrolase/transport protein Chain: O: PDB Molecule:atp synthase gamma chain; PDBTitle: structure of the e.coli f1-atp synthase inhibited by subunit epsilon 59 d1fs0g_ not modelled 9.2 21 Fold:Pyruvate kinase C-terminal domain-like Superfamily:ATP synthase (F1-ATPase), gamma subunit Family:ATP synthase (F1-ATPase), gamma subunit 60 c3e4cB_ not modelled 9.1 18 PDB header:hydrolase Chain: B: PDB Molecule:caspase-1; PDBTitle: procaspase-1 zymogen domain crystal strucutre 61 d1j08a1 not modelled 8.9 8 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:PDI-like 62 c3g7kD_ not modelled 8.9 13 PDB header:isomerase Chain: D: PDB Molecule:3-methylitaconate isomerase; PDBTitle: crystal structure of methylitaconate-delta-isomerase 63 d1umdb1 not modelled 8.8 15 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Branched-chain alpha-keto acid dehydrogenase Pyr module 64 d1v8za1 not modelled 8.5 4 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 65 d2jdig1 not modelled 8.5 30 Fold:Pyruvate kinase C-terminal domain-like Superfamily:ATP synthase (F1-ATPase), gamma subunit Family:ATP synthase (F1-ATPase), gamma subunit 66 c2w6jG_ not modelled 8.4 20 PDB header:hydrolase Chain: G: PDB Molecule:atp synthase subunit gamma, mitochondrial; PDBTitle: low resolution structures of bovine mitochondrial f1-atpase2 during controlled dehydration: hydration state 5. 67 c2qe7G_ not modelled 8.3 30 PDB header:hydrolase Chain: G: PDB Molecule:atp synthase subunit gamma; PDBTitle: crystal structure of the f1-atpase from the thermoalkaliphilic2 bacterium bacillus sp. ta2.a1 68 c3k35D_ not modelled 8.1 8 PDB header:hydrolase Chain: D: PDB Molecule:nad-dependent deacetylase sirtuin-6; PDBTitle: crystal structure of human sirt6 69 d1szpb1 not modelled 8.1 14 Fold:SAM domain-like Superfamily:Rad51 N-terminal domain-like Family:DNA repair protein Rad51, N-terminal domain 70 d1nw9b_ not modelled 7.9 12 Fold:Caspase-like Superfamily:Caspase-like Family:Caspase catalytic domain 71 d1xo1a2 not modelled 7.7 13 Fold:PIN domain-like Superfamily:PIN domain-like Family:5' to 3' exonuclease catalytic domain 72 c3eypB_ not modelled 7.3 16 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative alpha-l-fucosidase; PDBTitle: crystal structure of putative alpha-l-fucosidase from bacteroides2 thetaiotaomicron 73 d1uzxa_ not modelled 7.2 9 Fold:UBC-like Superfamily:UBC-like Family:UEV domain 74 c3qfnA_ not modelled 7.2 14 PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of streptococcal asymmetric ap4a hydrolase and2 phosphodiesterase spr1479/saph in complex with inorganic phosphate 75 d1yc5a1 not modelled 7.2 21 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 76 d2z1aa2 not modelled 7.1 17 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain 77 c1cp3B_ not modelled 7.0 21 PDB header:hydrolase/hydrolase inhibitor Chain: B: PDB Molecule:apopain; PDBTitle: crystal structure of the complex of apopain with the tetrapeptide2 inhibitor ace-dvad-fmc 78 d1n57a_ not modelled 6.9 8 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:DJ-1/PfpI 79 d1tfra2 not modelled 6.8 8 Fold:PIN domain-like Superfamily:PIN domain-like Family:5' to 3' exonuclease catalytic domain 80 d1uf3a_ not modelled 6.7 14 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:TT1561-like 81 d2pw6a1 not modelled 6.7 14 Fold:Phosphorylase/hydrolase-like Superfamily:LigB-like Family:LigB-like 82 d1a8la1 not modelled 6.6 6 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:PDI-like 83 c2o2jA_ not modelled 6.6 12 PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase beta chain; PDBTitle: mycobacterium tuberculosis tryptophan synthase beta chain2 dimer (apoform) 84 c3auzA_ not modelled 6.5 9 PDB header:recombination Chain: A: PDB Molecule:dna double-strand break repair protein mre11; PDBTitle: crystal structure of mre11 with manganese 85 c2xmoB_ not modelled 6.4 10 PDB header:hydrolase Chain: B: PDB Molecule:lmo2642 protein; PDBTitle: the crystal structure of lmo2642 86 c3pkiF_ not modelled 6.4 8 PDB header:hydrolase Chain: F: PDB Molecule:nad-dependent deacetylase sirtuin-6; PDBTitle: human sirt6 crystal structure in complex with adp ribose 87 d1usha2 not modelled 6.3 14 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain 88 c2x7lP_ not modelled 6.3 45 PDB header:immune system Chain: P: PDB Molecule:hiv rev; PDBTitle: implications of the hiv-1 rev dimer structure at 3.2a2 resolution for multimeric binding to the rev response3 element 89 d1ex9a_ not modelled 6.2 20 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Bacterial lipase 90 c1kmcB_ not modelled 6.2 19 PDB header:apoptosis/hydrolase Chain: B: PDB Molecule:caspase-7; PDBTitle: crystal structure of the caspase-7 / xiap-bir2 complex 91 d1m7ta_ not modelled 6.2 13 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 92 d2ozlb1 not modelled 6.1 12 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Branched-chain alpha-keto acid dehydrogenase Pyr module 93 c3siqF_ not modelled 6.1 14 PDB header:ligase Chain: F: PDB Molecule:apoptosis 1 inhibitor; PDBTitle: crystal structure of autoinhibited diap1-bir1 domain 94 d1hlga_ not modelled 6.0 9 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Gastric lipase 95 c2kncA_ not modelled 6.0 15 PDB header:cell adhesion Chain: A: PDB Molecule:integrin alpha-iib; PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex 96 d1w85b1 not modelled 6.0 12 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Branched-chain alpha-keto acid dehydrogenase Pyr module 97 d1uzdc1 not modelled 6.0 17 Fold:RuBisCO, small subunit Superfamily:RuBisCO, small subunit Family:RuBisCO, small subunit 98 c1w8xP_ not modelled 5.9 10 PDB header:virus Chain: P: PDB Molecule:protein p16; PDBTitle: structural analysis of prd1 99 d1ej7s_ not modelled 5.9 15 Fold:RuBisCO, small subunit Superfamily:RuBisCO, small subunit Family:RuBisCO, small subunit

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0