Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	N	I	A	I	V	T	I	N	Q	E	N	A	A	I	A	S	W	L	A	A	Q	D	F	S	G	C	T	L	A	H	W	Q	I	E	P	Q	P	V	V	A	E	Q	V	L	D	A	L	V	E	Q	W	Q	R	T	P	A	D	V	V
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	F	P	P	G	T	F	G	D	E	L	S	T	R	L	A	W	R	L	H	G	A	S	I	C	Q	V	T	S	L	D	I	P	T	V	S	V	R	K	S	H	W	G	N	A	L	T	A	T	L	Q	T	E	K	R	P	L	C	L	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	A	R	Q	A	G	A	A	K	N	A	T	L	P	S	G	M	Q	Q	L	N	I	V	P	G	A	L	P	D	W	L	V	S	T	E	D	L	K	N	V	T	R	D	P	L	A	E	A	R	R	V	L	V	V	G	Q	G	G	E	A
Secondary structure
SS confidence
Disorder			?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?							?	?	?	?	?	?								?	?	?	?	?	?	?	?												?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		D	N	Q	E	I	A	M	L	A	E	K	L	G	A	E	V	G	Y	S	R	A	R	V	M	N	G	G	V	D	A	E	K	V	I	G	I	S	G	H	L	L	A	P	E	V	C	I	V	V	G	A	S	G	A	A	A	L	M	A	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.
Sequence		V	R	N	S	K	F	V	V	A	I	N	H	D	A	S	A	A	V	F	S	Q	A	D	V	G	V	V	D	D	W	K	V	V	L	E	A	L	V	T	N	I	H	A	D	C	Q
Secondary structure
SS confidence
Disorder																																													?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1efp chain C Region: 24 - 281 Aligned: 247 Modelled: 258 Confidence: 100.0% Identity: 27% PDB header:electron transport Chain: C: PDB Molecule:protein (electron transfer flavoprotein); PDBTitle: electron transfer flavoprotein (etf) from paracoccus2 denitrificans Phyre2 PDB 1efv chain A domain 2 Region: 161 - 282 Aligned: 122 Modelled: 122 Confidence: 100.0% Identity: 38% Fold: DHS-like NAD/FAD-binding domain Superfamily: DHS-like NAD/FAD-binding domain Family: C-terminal domain of the electron transfer flavoprotein alpha subunit Phyre2 PDB 3cls chain D domain 2 Region: 162 - 281 Aligned: 120 Modelled: 120 Confidence: 100.0% Identity: 25% Fold: DHS-like NAD/FAD-binding domain Superfamily: DHS-like NAD/FAD-binding domain Family: C-terminal domain of the electron transfer flavoprotein alpha subunit Phyre2 PDB 1efp chain A domain 2 Region: 160 - 281 Aligned: 122 Modelled: 122 Confidence: 100.0% Identity: 42% Fold: DHS-like NAD/FAD-binding domain Superfamily: DHS-like NAD/FAD-binding domain Family: C-terminal domain of the electron transfer flavoprotein alpha subunit Phyre2 PDB 1efp chain A domain 1 Region: 20 - 158 Aligned: 136 Modelled: 139 Confidence: 99.8% Identity: 13% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: ETFP subunits Phyre2 PDB 1efv chain A domain 1 Region: 24 - 160 Aligned: 136 Modelled: 137 Confidence: 99.8% Identity: 15% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: ETFP subunits Phyre2 PDB 1t9g chain R Region: 24 - 150 Aligned: 126 Modelled: 127 Confidence: 99.8% Identity: 16% PDB header:oxidoreductase, electron transport Chain: R: PDB Molecule:electron transfer flavoprotein alpha-subunit, PDBTitle: structure of the human mcad:etf complex Phyre2 PDB 3ih5 chain A Region: 24 - 143 Aligned: 113 Modelled: 120 Confidence: 99.8% Identity: 18% PDB header:electron transport Chain: A: PDB Molecule:electron transfer flavoprotein alpha-subunit; PDBTitle: crystal structure of electron transfer flavoprotein alpha-2 subunit from bacteroides thetaiotaomicron Phyre2 PDB 3cls chain D domain 1 Region: 26 - 156 Aligned: 131 Modelled: 131 Confidence: 99.8% Identity: 9% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: ETFP subunits Phyre2 PDB 1o94 chain D Region: 25 - 152 Aligned: 128 Modelled: 128 Confidence: 99.8% Identity: 9% PDB header:electron transport Chain: D: PDB Molecule:electron transfer flavoprotein alpha-subunit; PDBTitle: ternary complex between trimethylamine dehydrogenase and2 electron transferring flavoprotein Phyre2 PDB 3fet chain A Region: 26 - 145 Aligned: 113 Modelled: 120 Confidence: 99.8% Identity: 15% PDB header:electron transport Chain: A: PDB Molecule:electron transfer flavoprotein subunit alpha related PDBTitle: crystal structure of the electron transfer flavoprotein subunit alpha2 related protein ta0212 from thermoplasma acidophilum Phyre2 PDB 1efp chain B Region: 26 - 132 Aligned: 104 Modelled: 107 Confidence: 98.9% Identity: 14% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: ETFP subunits Phyre2 PDB 1efv chain B Region: 26 - 132 Aligned: 104 Modelled: 107 Confidence: 98.9% Identity: 18% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: ETFP subunits Phyre2 PDB 3cls chain C domain 1 Region: 26 - 135 Aligned: 108 Modelled: 110 Confidence: 98.9% Identity: 17% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: ETFP subunits Phyre2 PDB 1o94 chain C Region: 26 - 132 Aligned: 105 Modelled: 107 Confidence: 98.8% Identity: 17% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: ETFP subunits Phyre2 PDB 1t9b chain A domain 1 Region: 165 - 286 Aligned: 122 Modelled: 122 Confidence: 98.6% Identity: 15% Fold: DHS-like NAD/FAD-binding domain Superfamily: DHS-like NAD/FAD-binding domain Family: Pyruvate oxidase and decarboxylase, middle domain Phyre2 PDB 1ozh chain A domain 1 Region: 165 - 282 Aligned: 118 Modelled: 118 Confidence: 98.5% Identity: 18% Fold: DHS-like NAD/FAD-binding domain Superfamily: DHS-like NAD/FAD-binding domain Family: Pyruvate oxidase and decarboxylase, middle domain Phyre2 PDB 2ez9 chain A domain 1 Region: 165 - 282 Aligned: 118 Modelled: 118 Confidence: 98.5% Identity: 19% Fold: DHS-like NAD/FAD-binding domain Superfamily: DHS-like NAD/FAD-binding domain Family: Pyruvate oxidase and decarboxylase, middle domain Phyre2 PDB 2ji7 chain A domain 1 Region: 165 - 283 Aligned: 119 Modelled: 119 Confidence: 98.2% Identity: 18% Fold: DHS-like NAD/FAD-binding domain Superfamily: DHS-like NAD/FAD-binding domain Family: Pyruvate oxidase and decarboxylase, middle domain Phyre2 PDB 2iht chain A domain 1 Region: 165 - 283 Aligned: 119 Modelled: 119 Confidence: 98.0% Identity: 29% Fold: DHS-like NAD/FAD-binding domain Superfamily: DHS-like NAD/FAD-binding domain Family: Pyruvate oxidase and decarboxylase, middle domain Phyre2 PDB 1y5e chain A domain 1 Region: 1 - 79 Aligned: 77 Modelled: 77 Confidence: 74.5% Identity: 19% Fold: Molybdenum cofactor biosynthesis proteins Superfamily: Molybdenum cofactor biosynthesis proteins Family: MogA-like Phyre2 1 c1efpC_ 2 d1efva2 3 d3clsd2 4 d1efpa2 5 d1efpa1 6 d1efva1 7 c1t9gR_ 8 c3ih5A_ 9 d3clsd1 10 c1o94D_ 11 c3fetA_ 12 d1efpb_ 13 d1efvb_ 14 d3clsc1 15 d1o94c_ 16 d1t9ba1 17 d1ozha1 18 d2ez9a1 19 d2ji7a1 20 d2ihta1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 d1y5ea1 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1efpC_ 100.0 27 PDB header:electron transport Chain: C: PDB Molecule:protein (electron transfer flavoprotein); PDBTitle: electron transfer flavoprotein (etf) from paracoccus2 denitrificans 2 d1efva2 100.0 38 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:C-terminal domain of the electron transfer flavoprotein alpha subunit 3 d3clsd2 100.0 25 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:C-terminal domain of the electron transfer flavoprotein alpha subunit 4 d1efpa2 100.0 42 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:C-terminal domain of the electron transfer flavoprotein alpha subunit 5 d1efpa1 99.8 13 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ETFP subunits 6 d1efva1 99.8 15 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ETFP subunits 7 c1t9gR_ 99.8 16 PDB header:oxidoreductase, electron transport Chain: R: PDB Molecule:electron transfer flavoprotein alpha-subunit, PDBTitle: structure of the human mcad:etf complex 8 c3ih5A_ 99.8 18 PDB header:electron transport Chain: A: PDB Molecule:electron transfer flavoprotein alpha-subunit; PDBTitle: crystal structure of electron transfer flavoprotein alpha-2 subunit from bacteroides thetaiotaomicron 9 d3clsd1 99.8 9 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ETFP subunits 10 c1o94D_ 99.8 9 PDB header:electron transport Chain: D: PDB Molecule:electron transfer flavoprotein alpha-subunit; PDBTitle: ternary complex between trimethylamine dehydrogenase and2 electron transferring flavoprotein 11 c3fetA_ 99.8 15 PDB header:electron transport Chain: A: PDB Molecule:electron transfer flavoprotein subunit alpha related PDBTitle: crystal structure of the electron transfer flavoprotein subunit alpha2 related protein ta0212 from thermoplasma acidophilum 12 d1efpb_ 98.9 14 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ETFP subunits 13 d1efvb_ 98.9 18 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ETFP subunits 14 d3clsc1 98.9 17 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ETFP subunits 15 d1o94c_ 98.8 17 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ETFP subunits 16 d1t9ba1 98.6 15 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 17 d1ozha1 98.5 18 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 18 d2ez9a1 98.5 19 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 19 d2ji7a1 98.2 18 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 20 d2ihta1 98.0 29 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 21 d1ybha1 not modelled 97.7 20 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 22 d2djia1 not modelled 97.7 20 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 23 d1q6za1 not modelled 97.5 18 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 24 c1powA_ not modelled 97.5 20 PDB header:oxidoreductase(oxygen as acceptor) Chain: A: PDB Molecule:pyruvate oxidase; PDBTitle: the refined structures of a stabilized mutant and of wild-type2 pyruvate oxidase from lactobacillus plantarum 25 c1ozhD_ not modelled 97.4 20 PDB header:lyase Chain: D: PDB Molecule:acetolactate synthase, catabolic; PDBTitle: the crystal structure of klebsiella pneumoniae acetolactate2 synthase with enzyme-bound cofactor and with an unusual3 intermediate. 26 c2djiA_ not modelled 97.3 21 PDB header:oxidoreductase Chain: A: PDB Molecule:pyruvate oxidase; PDBTitle: crystal structure of pyruvate oxidase from aerococcus2 viridans containing fad 27 c2q27B_ not modelled 97.2 15 PDB header:lyase Chain: B: PDB Molecule:oxalyl-coa decarboxylase; PDBTitle: crystal structure of oxalyl-coa decarboxylase from escherichia coli 28 c2pgnA_ not modelled 97.0 21 PDB header:hydrolase Chain: A: PDB Molecule:cyclohexane-1,2-dione hydrolase (cdh); PDBTitle: the crystal structure of fad and thdp-dependent cyclohexane-1,2-dione2 hydrolase in complex with cyclohexane-1,2-dione 29 c1yi1A_ not modelled 96.9 22 PDB header:transferase Chain: A: PDB Molecule:acetolactate synthase; PDBTitle: crystal structure of arabidopsis thaliana acetohydroxyacid synthase in2 complex with a sulfonylurea herbicide, tribenuron methyl 30 c2x7jA_ not modelled 96.9 21 PDB header:transferase Chain: A: PDB Molecule:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene PDBTitle: structure of the menaquinone biosynthesis protein mend from2 bacillus subtilis 31 c3eyaE_ not modelled 96.8 18 PDB header:oxidoreductase Chain: E: PDB Molecule:pyruvate dehydrogenase [cytochrome]; PDBTitle: structural basis for membrane binding and catalytic2 activation of the peripheral membrane enzyme pyruvate3 oxidase from escherichia coli 32 c1t9dB_ not modelled 96.8 20 PDB header:transferase Chain: B: PDB Molecule:acetolactate synthase, mitochondrial; PDBTitle: crystal structure of yeast acetohydroxyacid synthase in2 complex with a sulfonylurea herbicide, metsulfuron methyl 33 c2ji6B_ not modelled 96.7 22 PDB header:lyase Chain: B: PDB Molecule:oxalyl-coa decarboxylase; PDBTitle: x-ray structure of oxalyl-coa decarboxylase in complex with2 3-deaza-thdp and oxalyl-coa 34 c3lq1A_ not modelled 96.6 20 PDB header:transferase Chain: A: PDB Molecule:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- PDBTitle: crystal structure of 2-succinyl-6-hydroxy-2,4-cyclohexadiene2 1-carboxylic acid synthase/2-oxoglutarate decarboxylase3 from listeria monocytogenes str. 4b f2365 35 c2ag1A_ not modelled 96.2 23 PDB header:lyase Chain: A: PDB Molecule:benzaldehyde lyase; PDBTitle: crystal structure of benzaldehyde lyase (bal)- semet 36 c2panF_ not modelled 95.9 24 PDB header:lyase Chain: F: PDB Molecule:glyoxylate carboligase; PDBTitle: crystal structure of e. coli glyoxylate carboligase 37 d1pvda1 not modelled 95.8 18 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 38 c1upaC_ not modelled 95.7 28 PDB header:synthase Chain: C: PDB Molecule:carboxyethylarginine synthase; PDBTitle: carboxyethylarginine synthase from streptomyces2 clavuligerus (semet structure) 39 d1yc5a1 not modelled 95.6 19 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 40 d1m2ka_ not modelled 95.6 28 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 41 d2b4ya1 not modelled 95.4 21 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 42 c2v3wC_ not modelled 95.0 22 PDB header:lyase Chain: C: PDB Molecule:benzoylformate decarboxylase; PDBTitle: crystal structure of the benzoylformate decarboxylase2 variant l461a from pseudomonas putida 43 d1zpda1 not modelled 95.0 18 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 44 c1jscA_ not modelled 94.8 23 PDB header:lyase Chain: A: PDB Molecule:acetohydroxy-acid synthase; PDBTitle: crystal structure of the catalytic subunit of yeast2 acetohydroxyacid synthase: a target for herbicidal3 inhibitors 45 c3glsC_ not modelled 94.1 27 PDB header:hydrolase Chain: C: PDB Molecule:nad-dependent deacetylase sirtuin-3, PDBTitle: crystal structure of human sirt3 46 c3k35D_ not modelled 94.0 17 PDB header:hydrolase Chain: D: PDB Molecule:nad-dependent deacetylase sirtuin-6; PDBTitle: crystal structure of human sirt6 47 d1ma3a_ not modelled 94.0 18 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 48 c2jlaD_ not modelled 93.2 13 PDB header:transferase Chain: D: PDB Molecule:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene PDBTitle: crystal structure of e.coli mend, 2-succinyl-5-enolpyruvyl-2 6-hydroxy-3-cyclohexadiene-1-carboxylate synthase - semet3 protein 49 c3pkiF_ not modelled 93.0 17 PDB header:hydrolase Chain: F: PDB Molecule:nad-dependent deacetylase sirtuin-6; PDBTitle: human sirt6 crystal structure in complex with adp ribose 50 d1q1aa_ not modelled 92.9 25 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 51 d1s5pa_ not modelled 92.1 20 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 52 c2vbiF_ not modelled 91.5 18 PDB header:lyase Chain: F: PDB Molecule:pyruvate decarboxylase; PDBTitle: holostructure of pyruvate decarboxylase from acetobacter2 pasteurianus 53 c3jwpA_ not modelled 91.4 19 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulatory protein sir2 homologue; PDBTitle: crystal structure of plasmodium falciparum sir2a (pf13_0152) in2 complex with amp 54 c1q14A_ not modelled 90.3 25 PDB header:hydrolase Chain: A: PDB Molecule:hst2 protein; PDBTitle: structure and autoregulation of the yeast hst2 homolog of sir2 55 c1zpdA_ not modelled 90.1 16 PDB header:alcohol fermentation Chain: A: PDB Molecule:pyruvate decarboxylase; PDBTitle: pyruvate decarboxylase from zymomonas mobilis 56 d1j8fa_ not modelled 86.6 18 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 57 c2hjhB_ not modelled 86.6 17 PDB header:hydrolase Chain: B: PDB Molecule:nad-dependent histone deacetylase sir2; PDBTitle: crystal structure of the sir2 deacetylase 58 c2w93A_ not modelled 85.8 15 PDB header:lyase Chain: A: PDB Molecule:pyruvate decarboxylase isozyme 1; PDBTitle: crystal structure of the saccharomyces cerevisiae pyruvate2 decarboxylase variant e477q in complex with the surrogate3 pyruvamide 59 d1l1qa_ not modelled 84.7 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 60 c2dy0A_ not modelled 82.4 19 PDB header:transferase Chain: A: PDB Molecule:adenine phosphoribosyltransferase; PDBTitle: crystal structure of project jw0458 from escherichia coli 61 c2vbgB_ not modelled 78.6 12 PDB header:lyase Chain: B: PDB Molecule:branched-chain alpha-ketoacid decarboxylase; PDBTitle: the complex structure of the branched-chain keto acid2 decarboxylase (kdca) from lactococcus lactis with 2r-1-3 hydroxyethyl-deazathdp 62 c3cf4G_ not modelled 77.0 12 PDB header:oxidoreductase Chain: G: PDB Molecule:acetyl-coa decarboxylase/synthase epsilon subunit; PDBTitle: structure of the codh component of the m. barkeri acds complex 63 c2x3yA_ not modelled 76.8 17 PDB header:isomerase Chain: A: PDB Molecule:phosphoheptose isomerase; PDBTitle: crystal structure of gmha from burkholderia pseudomallei 64 d1y5ea1 74.5 19 Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MogA-like 65 d1x94a_ not modelled 73.9 17 Fold:SIS domain Superfamily:SIS domain Family:mono-SIS domain 66 d1zn7a1 not modelled 71.8 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 67 d1y0ba1 not modelled 68.1 9 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 68 d1mkza_ not modelled 67.0 16 Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MogA-like 69 d1o57a2 not modelled 66.9 23 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 70 c1o57A_ not modelled 66.4 23 PDB header:dna binding protein Chain: A: PDB Molecule:pur operon repressor; PDBTitle: crystal structure of the purine operon repressor of2 bacillus subtilis 71 d1mzva_ not modelled 65.8 18 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 72 c2nxwB_ not modelled 60.4 23 PDB header:lyase Chain: B: PDB Molecule:phenyl-3-pyruvate decarboxylase; PDBTitle: crystal structure of phenylpyruvate decarboxylase of azospirillum2 brasilense 73 d1tk9a_ not modelled 60.0 17 Fold:SIS domain Superfamily:SIS domain Family:mono-SIS domain 74 d1qb7a_ not modelled 59.4 18 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 75 c2x5eA_ not modelled 58.4 14 PDB header:unknown function Chain: A: PDB Molecule:upf0271 protein pa4511; PDBTitle: crystal structure of the hypothetical protein pa4511 from2 pseudomonas aeruginosa 76 c3dezA_ not modelled 55.9 17 PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: crystal structure of orotate phosphoribosyltransferase from2 streptococcus mutans 77 d1moqa_ not modelled 51.0 11 Fold:SIS domain Superfamily:SIS domain Family:double-SIS domain 78 c1ovmC_ not modelled 50.2 17 PDB header:lyase Chain: C: PDB Molecule:indole-3-pyruvate decarboxylase; PDBTitle: crystal structure of indolepyruvate decarboxylase from2 enterobacter cloacae 79 d1kjqa2 not modelled 48.5 18 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 80 d1xw8a_ not modelled 45.5 18 Fold:7-stranded beta/alpha barrel Superfamily:Glycoside hydrolase/deacetylase Family:LamB/YcsF-like 81 d1v6ta_ not modelled 45.3 19 Fold:7-stranded beta/alpha barrel Superfamily:Glycoside hydrolase/deacetylase Family:LamB/YcsF-like 82 c2wnsB_ not modelled 42.0 17 PDB header:transferase Chain: B: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: human orotate phosphoribosyltransferase (oprtase) domain of2 uridine 5'-monophosphate synthase (umps) in complex with3 its substrate orotidine 5'-monophosphate (omp) 83 c2xhzC_ not modelled 41.4 19 PDB header:isomerase Chain: C: PDB Molecule:arabinose 5-phosphate isomerase; PDBTitle: probing the active site of the sugar isomerase domain from e. coli2 arabinose-5-phosphate isomerase via x-ray crystallography 84 c2is8A_ not modelled 41.0 20 PDB header:structural protein Chain: A: PDB Molecule:molybdopterin biosynthesis enzyme, moab; PDBTitle: crystal structure of the molybdopterin biosynthesis enzyme moab2 (ttha0341) from thermus theromophilus hb8 85 c3d3qB_ not modelled 38.4 33 PDB header:transferase Chain: B: PDB Molecule:trna delta(2)-isopentenylpyrophosphate PDBTitle: crystal structure of trna delta(2)-isopentenylpyrophosphate2 transferase (se0981) from staphylococcus epidermidis.3 northeast structural genomics consortium target ser100 86 d2dfaa1 not modelled 38.3 15 Fold:7-stranded beta/alpha barrel Superfamily:Glycoside hydrolase/deacetylase Family:LamB/YcsF-like 87 c2p3wB_ not modelled 37.9 24 PDB header:protein binding Chain: B: PDB Molecule:probable serine protease htra3; PDBTitle: crystal structure of the htra3 pdz domain bound to a phage-derived2 ligand (fgrwv) 88 d1jlja_ not modelled 36.8 15 Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MogA-like 89 d3bzka5 not modelled 36.4 18 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Tex RuvX-like domain-like 90 c1nriA_ not modelled 35.4 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein hi0754; PDBTitle: crystal structure of putative phosphosugar isomerase hi0754 from2 haemophilus influenzae 91 d1nria_ not modelled 35.4 18 Fold:SIS domain Superfamily:SIS domain Family:mono-SIS domain 92 c3tbfA_ not modelled 35.0 12 PDB header:transferase Chain: A: PDB Molecule:glucosamine--fructose-6-phosphate aminotransferase PDBTitle: c-terminal domain of glucosamine-fructose-6-phosphate aminotransferase2 from francisella tularensis. 93 c2pn1A_ not modelled 34.2 17 PDB header:ligase Chain: A: PDB Molecule:carbamoylphosphate synthase large subunit; PDBTitle: crystal structure of carbamoylphosphate synthase large subunit (split2 gene in mj) (zp_00538348.1) from exiguobacterium sp. 255-15 at 2.00 a3 resolution 94 c3eplA_ not modelled 33.1 27 PDB header:transferase/rna Chain: A: PDB Molecule:trna isopentenyltransferase; PDBTitle: crystallographic snapshots of eukaryotic2 dimethylallyltransferase acting on trna: insight into trna3 recognition and reaction mechanism 95 d1a2za_ not modelled 31.4 11 Fold:Phosphorylase/hydrolase-like Superfamily:Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) Family:Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) 96 d1nt2a_ not modelled 30.6 9 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Fibrillarin homologue 97 c2amlB_ not modelled 30.3 22 PDB header:transferase Chain: B: PDB Molecule:sis domain protein; PDBTitle: crystal structure of lmo0035 protein (46906266) from listeria2 monocytogenes 4b f2365 at 1.50 a resolution 98 c2ze5A_ not modelled 30.2 11 PDB header:transferase Chain: A: PDB Molecule:isopentenyl transferase; PDBTitle: crystal structure of adenosine phosphate-isopentenyltransferase 99 c3psiA_ not modelled 30.1 19 PDB header:transcription Chain: A: PDB Molecule:transcription elongation factor spt6; PDBTitle: crystal structure of the spt6 core domain from saccharomyces2 cerevisiae, form spt6(239-1451) 100 c3fozB_ not modelled 30.1 27 PDB header:transferase/rna Chain: B: PDB Molecule:trna delta(2)-isopentenylpyrophosphate transferase; PDBTitle: structure of e. coli isopentenyl-trna transferase in complex with e.2 coli trna(phe) 101 d1pama3 not modelled 29.9 38 Fold:Glycosyl hydrolase domain Superfamily:Glycosyl hydrolase domain Family:alpha-Amylases, C-terminal beta-sheet domain 102 c1kjjA_ not modelled 29.8 18 PDB header:transferase Chain: A: PDB Molecule:phosphoribosylglycinamide formyltransferase 2; PDBTitle: crystal structure of glycniamide ribonucleotide2 transformylase in complex with mg-atp-gamma-s 103 c3uvzB_ not modelled 28.1 15 PDB header:lyase Chain: B: PDB Molecule:phosphoribosylaminoimidazole carboxylase, atpase subunit; PDBTitle: crystal structure of phosphoribosylaminoimidazole carboxylase, atpase2 subunit from burkholderia ambifaria 104 d1g8sa_ not modelled 28.0 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Fibrillarin homologue 105 d1g2qa_ not modelled 26.9 12 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 106 c2p1zA_ not modelled 26.3 11 PDB header:transferase Chain: A: PDB Molecule:phosphoribosyltransferase; PDBTitle: crystal structure of phosphoribosyltransferase from corynebacterium2 diphtheriae 107 d1auga_ not modelled 26.3 27 Fold:Phosphorylase/hydrolase-like Superfamily:Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) Family:Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) 108 d1di6a_ not modelled 26.0 20 Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MogA-like 109 c3lacA_ not modelled 25.5 18 PDB header:hydrolase Chain: A: PDB Molecule:pyrrolidone-carboxylate peptidase; PDBTitle: crystal structure of bacillus anthracis pyrrolidone-carboxylate2 peptidase, pcp 110 d1qh8b_ not modelled 25.2 11 Fold:Chelatase-like Superfamily:"Helical backbone" metal receptor Family:Nitrogenase iron-molybdenum protein 111 d2iyva1 not modelled 24.8 24 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Shikimate kinase (AroK) 112 d2aeea1 not modelled 24.7 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 113 d1iofa_ not modelled 24.5 20 Fold:Phosphorylase/hydrolase-like Superfamily:Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) Family:Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) 114 d1cxla3 not modelled 24.2 31 Fold:Glycosyl hydrolase domain Superfamily:Glycosyl hydrolase domain Family:alpha-Amylases, C-terminal beta-sheet domain 115 d1w44a_ not modelled 23.1 31 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RecA protein-like (ATPase-domain) 116 d1vcha1 not modelled 22.3 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 117 c3imkA_ not modelled 21.5 29 PDB header:metal binding protein Chain: A: PDB Molecule:putative molybdenum carrier protein; PDBTitle: crystal structure of putative molybdenum carrier protein (yp_461806.1)2 from syntrophus aciditrophicus sb at 1.45 a resolution 118 d1qhoa3 not modelled 20.9 31 Fold:Glycosyl hydrolase domain Superfamily:Glycosyl hydrolase domain Family:alpha-Amylases, C-terminal beta-sheet domain 119 c2jtvA_ not modelled 20.3 27 PDB header:structural genomics Chain: A: PDB Molecule:protein of unknown function; PDBTitle: solution structure of protein rpa3401, northeast structural genomics2 consortium target rpt7, ontario center for structural proteomics3 target rp3384 120 d1cgta3 not modelled 20.3 38 Fold:Glycosyl hydrolase domain Superfamily:Glycosyl hydrolase domain Family:alpha-Amylases, C-terminal beta-sheet domain

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0