Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP04335
DateThu Jan 5 10:58:13 GMT 2012
Unique Job ID8221a05f06a0b290

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3mveB_
Top template information
PDB header:lyase
Chain: B: PDB Molecule:upf0255 protein vv1_0328;
PDBTitle: crystal structure of a novel pyruvate decarboxylase
Confidence and coverage
Confidence:100.0% Coverage: 95%
392 residues ( 95% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MTQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTIPHWYRMINRLMWIWRG
Secondary structure 
SS confidence 
Disorder  ???????
???????
???????
??
?
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  IDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWATQAMVWQQKACAEDDPQL
Secondary structure 
SS confidence 
Disorder 
???
?
??
????
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  SGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEAAQRLPGTMRQMEFTVPGGAP
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  ITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYFAPRGIAMLTIDMPSVGFSSKWK
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  LTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGANVAVRLAYLESPRLKAVACLGPVV
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  HTLLSDFKCQQQVPEMYLDVLASRLGMHDASDEALRVELNRYSLKVQGLLGRRCPTPMLS
Secondary structure 
SS confidence 
Disorder 
??
?
?
Disorder confidence 
 
   .........370.........380.........390.........400.........410....
Sequence  GYWKNDPFSPEEDSRLITSSSADGKLLEIPFNPVYRNFDKGLQEITDWIEKRLC
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3mve chain B

3D model

Region: 18 - 413
Aligned: 392
Modelled: 394
Confidence: 100.0%
Identity: 42%
PDB header:lyase
Chain: B: PDB Molecule:upf0255 protein vv1_0328;
PDBTitle: crystal structure of a novel pyruvate decarboxylase

Phyre2

PDB 2jbw chain A domain 1

3D model

Region: 55 - 414
Aligned: 327
Modelled: 335
Confidence: 100.0%
Identity: 21%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: 2,6-dihydropseudooxynicotine hydrolase-like

Phyre2

PDB 3fnb chain B

3D model

Region: 48 - 413
Aligned: 340
Modelled: 350
Confidence: 100.0%
Identity: 14%
PDB header:hydrolase
Chain: B: PDB Molecule:acylaminoacyl peptidase smu_737;
PDBTitle: crystal structure of acylaminoacyl peptidase smu_737 from2 streptococcus mutans ua159

Phyre2

PDB 2jbw chain B

3D model

Region: 55 - 414
Aligned: 327
Modelled: 340
Confidence: 100.0%
Identity: 20%
PDB header:hydrolase
Chain: B: PDB Molecule:2,6-dihydroxy-pseudo-oxynicotine hydrolase;
PDBTitle: crystal structure of the 2,6-dihydroxy-pseudo-oxynicotine2 hydrolase.

Phyre2

PDB 2ecf chain A

3D model

Region: 161 - 413
Aligned: 235
Modelled: 253
Confidence: 100.0%
Identity: 19%
PDB header:hydrolase
Chain: A: PDB Molecule:dipeptidyl peptidase iv;
PDBTitle: crystal structure of dipeptidyl aminopeptidase iv from2 stenotrophomonas maltophilia

Phyre2

PDB 1l7a chain A

3D model

Region: 167 - 413
Aligned: 240
Modelled: 247
Confidence: 100.0%
Identity: 18%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: Acetyl xylan esterase-like

Phyre2

PDB 2eep chain A

3D model

Region: 166 - 413
Aligned: 230
Modelled: 237
Confidence: 100.0%
Identity: 18%
PDB header:hydrolase
Chain: A: PDB Molecule:dipeptidyl aminopeptidase iv, putative;
PDBTitle: prolyl tripeptidyl aminopeptidase complexed with an inhibitor

Phyre2

PDB 3azq chain A

3D model

Region: 166 - 413
Aligned: 237
Modelled: 248
Confidence: 100.0%
Identity: 18%
PDB header:hydrolase
Chain: A: PDB Molecule:aminopeptidase;
PDBTitle: crystal structure of puromycin hydrolase s511a mutant complexed with2 pgg

Phyre2

PDB 2hu7 chain A

3D model

Region: 167 - 413
Aligned: 231
Modelled: 247
Confidence: 100.0%
Identity: 12%
PDB header:hydrolase
Chain: A: PDB Molecule:acylamino-acid-releasing enzyme;
PDBTitle: binding of inhibitors by acylaminoacyl peptidase

Phyre2

PDB 2g5t chain A

3D model

Region: 155 - 413
Aligned: 243
Modelled: 259
Confidence: 100.0%
Identity: 13%
PDB header:hydrolase
Chain: A: PDB Molecule:dipeptidyl peptidase 4;
PDBTitle: crystal structure of human dipeptidyl peptidase iv (dppiv)2 complexed with cyanopyrrolidine (c5-pro-pro) inhibitor 21ag

Phyre2

PDB 1z68 chain A

3D model

Region: 155 - 413
Aligned: 243
Modelled: 259
Confidence: 100.0%
Identity: 12%
PDB header:lyase
Chain: A: PDB Molecule:fibroblast activation protein, alpha subunit;
PDBTitle: crystal structure of human fibroblast activation protein alpha

Phyre2

PDB 2qtb chain B

3D model

Region: 155 - 413
Aligned: 243
Modelled: 259
Confidence: 100.0%
Identity: 13%
PDB header:hydrolase
Chain: B: PDB Molecule:dipeptidyl peptidase 4;
PDBTitle: human dipeptidyl peptidase iv/cd26 in complex with a 4-aryl2 cyclohexylalanine inhibitor

Phyre2

PDB 1vlq chain A

3D model

Region: 165 - 413
Aligned: 240
Modelled: 249
Confidence: 100.0%
Identity: 17%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: Acetyl xylan esterase-like

Phyre2

PDB 3hlk chain B

3D model

Region: 163 - 413
Aligned: 243
Modelled: 251
Confidence: 100.0%
Identity: 16%
PDB header:hydrolase
Chain: B: PDB Molecule:acyl-coenzyme a thioesterase 2, mitochondrial;
PDBTitle: crystal structure of human mitochondrial acyl-coa2 thioesterase (acot2)

Phyre2

PDB 3g8y chain A

3D model

Region: 101 - 413
Aligned: 301
Modelled: 313
Confidence: 100.0%
Identity: 15%
PDB header:hydrolase
Chain: A: PDB Molecule:susd/ragb-associated esterase-like protein;
PDBTitle: crystal structure of a putative hydrolase (bvu_4111) from bacteroides2 vulgatus atcc 8482 at 1.90 a resolution

Phyre2

PDB 1l7q chain A

3D model

Region: 165 - 413
Aligned: 248
Modelled: 249
Confidence: 100.0%
Identity: 15%
PDB header:hydrolase
Chain: A: PDB Molecule:cocaine esterase;
PDBTitle: ser117ala mutant of bacterial cocaine esterase coce

Phyre2

PDB 3ib3 chain A

3D model

Region: 169 - 414
Aligned: 245
Modelled: 246
Confidence: 100.0%
Identity: 13%
PDB header:hydrolase
Chain: A: PDB Molecule:coce/nond family hydrolase;
PDBTitle: crystal structure of sacol2612 - coce/nond family hydrolase from2 staphylococcus aureus

Phyre2

PDB 3k2i chain A

3D model

Region: 163 - 413
Aligned: 243
Modelled: 251
Confidence: 100.0%
Identity: 15%
PDB header:hydrolase
Chain: A: PDB Molecule:acyl-coenzyme a thioesterase 4;
PDBTitle: human acyl-coenzyme a thioesterase 4

Phyre2

PDB 2hdw chain B

3D model

Region: 165 - 413
Aligned: 247
Modelled: 249
Confidence: 100.0%
Identity: 18%
PDB header:hydrolase
Chain: B: PDB Molecule:hypothetical protein pa2218;
PDBTitle: crystal structure of hypothetical protein pa2218 from pseudomonas2 aeruginosa

Phyre2

PDB 1ju3 chain A domain 2

3D model

Region: 165 - 413
Aligned: 248
Modelled: 249
Confidence: 100.0%
Identity: 17%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: PepX catalytic domain-like

Phyre2
1
c3mveB_
2
d2jbwa1
3
c3fnbB_
4
c2jbwB_
5
c2ecfA_
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d1l7aa_
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c2eepA_
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c3azqA_
9
c2hu7A_
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c2g5tA_
11
c1z68A_
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c2qtbB_
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d1vlqa_
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c3hlkB_
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c3g8yA_
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c1l7qA_
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c3ib3A_
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c3k2iA_
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c2hdwB_
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d1ju3a2
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3mveB_
100.0 42 PDB header:lyase
Chain: B: PDB Molecule:upf0255 protein vv1_0328;
PDBTitle: crystal structure of a novel pyruvate decarboxylase
2d2jbwa1
100.0 21 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:2,6-dihydropseudooxynicotine hydrolase-like
3c3fnbB_
100.0 14 PDB header:hydrolase
Chain: B: PDB Molecule:acylaminoacyl peptidase smu_737;
PDBTitle: crystal structure of acylaminoacyl peptidase smu_737 from2 streptococcus mutans ua159
4c2jbwB_
100.0 20 PDB header:hydrolase
Chain: B: PDB Molecule:2,6-dihydroxy-pseudo-oxynicotine hydrolase;
PDBTitle: crystal structure of the 2,6-dihydroxy-pseudo-oxynicotine2 hydrolase.
5c2ecfA_
100.0 19 PDB header:hydrolase
Chain: A: PDB Molecule:dipeptidyl peptidase iv;
PDBTitle: crystal structure of dipeptidyl aminopeptidase iv from2 stenotrophomonas maltophilia
6d1l7aa_
100.0 18 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Acetyl xylan esterase-like
7c2eepA_
100.0 18 PDB header:hydrolase
Chain: A: PDB Molecule:dipeptidyl aminopeptidase iv, putative;
PDBTitle: prolyl tripeptidyl aminopeptidase complexed with an inhibitor
8c3azqA_
100.0 18 PDB header:hydrolase
Chain: A: PDB Molecule:aminopeptidase;
PDBTitle: crystal structure of puromycin hydrolase s511a mutant complexed with2 pgg
9c2hu7A_
100.0 12 PDB header:hydrolase
Chain: A: PDB Molecule:acylamino-acid-releasing enzyme;
PDBTitle: binding of inhibitors by acylaminoacyl peptidase
10c2g5tA_
100.0 13 PDB header:hydrolase
Chain: A: PDB Molecule:dipeptidyl peptidase 4;
PDBTitle: crystal structure of human dipeptidyl peptidase iv (dppiv)2 complexed with cyanopyrrolidine (c5-pro-pro) inhibitor 21ag
11c1z68A_
100.0 12 PDB header:lyase
Chain: A: PDB Molecule:fibroblast activation protein, alpha subunit;
PDBTitle: crystal structure of human fibroblast activation protein alpha
12c2qtbB_
100.0 13 PDB header:hydrolase
Chain: B: PDB Molecule:dipeptidyl peptidase 4;
PDBTitle: human dipeptidyl peptidase iv/cd26 in complex with a 4-aryl2 cyclohexylalanine inhibitor
13d1vlqa_
100.0 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Acetyl xylan esterase-like
14c3hlkB_
100.0 16 PDB header:hydrolase
Chain: B: PDB Molecule:acyl-coenzyme a thioesterase 2, mitochondrial;
PDBTitle: crystal structure of human mitochondrial acyl-coa2 thioesterase (acot2)
15c3g8yA_
100.0 15 PDB header:hydrolase
Chain: A: PDB Molecule:susd/ragb-associated esterase-like protein;
PDBTitle: crystal structure of a putative hydrolase (bvu_4111) from bacteroides2 vulgatus atcc 8482 at 1.90 a resolution
16c1l7qA_
100.0 15 PDB header:hydrolase
Chain: A: PDB Molecule:cocaine esterase;
PDBTitle: ser117ala mutant of bacterial cocaine esterase coce
17c3ib3A_
100.0 13 PDB header:hydrolase
Chain: A: PDB Molecule:coce/nond family hydrolase;
PDBTitle: crystal structure of sacol2612 - coce/nond family hydrolase from2 staphylococcus aureus
18c3k2iA_
100.0 15 PDB header:hydrolase
Chain: A: PDB Molecule:acyl-coenzyme a thioesterase 4;
PDBTitle: human acyl-coenzyme a thioesterase 4
19c2hdwB_
100.0 18 PDB header:hydrolase
Chain: B: PDB Molecule:hypothetical protein pa2218;
PDBTitle: crystal structure of hypothetical protein pa2218 from pseudomonas2 aeruginosa
20d1ju3a2
100.0 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:PepX catalytic domain-like
21c3fcyB_
not modelled 100.0 19 PDB header:hydrolase
Chain: B: PDB Molecule:xylan esterase 1;
PDBTitle: crystal structure of acetyl xylan esterase 1 from2 thermoanaerobacterium sp. jw/sl ys485
22c2o2gA_
not modelled 100.0 20 PDB header:hydrolase
Chain: A: PDB Molecule:dienelactone hydrolase;
PDBTitle: crystal structure of dienelactone hydrolase (yp_324580.1) from2 anabaena variabilis atcc 29413 at 1.92 a resolution
23d1hlga_
not modelled 100.0 15 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Gastric lipase
24c2b9vB_
not modelled 100.0 15 PDB header:hydrolase
Chain: B: PDB Molecule:alpha-amino acid ester hydrolase;
PDBTitle: acetobacter turbidans alpha-amino acid ester hydrolase
25c2bklB_
not modelled 100.0 12 PDB header:hydrolase
Chain: B: PDB Molecule:prolyl endopeptidase;
PDBTitle: structural and mechanistic analysis of two prolyl2 endopeptidases: role of inter-domain dynamics in3 catalysis and specificity
26c1xfdD_
not modelled 100.0 15 PDB header:membrane protein
Chain: D: PDB Molecule:dipeptidyl aminopeptidase-like protein 6;
PDBTitle: structure of a human a-type potassium channel accelerating factor2 dppx, a member of the dipeptidyl aminopeptidase family
27d2b9va2
not modelled 100.0 14 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:PepX catalytic domain-like
28c3ksrA_
not modelled 99.9 16 PDB header:hydrolase
Chain: A: PDB Molecule:putative serine hydrolase;
PDBTitle: crystal structure of a putative serine hydrolase (xcc3885) from2 xanthomonas campestris pv. campestris at 2.69 a resolution
29d1k8qa_
not modelled 99.9 14 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Gastric lipase
30c1qfmA_
not modelled 99.9 15 PDB header:hydrolase
Chain: A: PDB Molecule:protein (prolyl oligopeptidase);
PDBTitle: prolyl oligopeptidase from porcine muscle
31d1mpxa2
not modelled 99.9 15 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:PepX catalytic domain-like
32c2xe4A_
not modelled 99.9 14 PDB header:hydrolase/inhibitor
Chain: A: PDB Molecule:oligopeptidase b;
PDBTitle: structure of oligopeptidase b from leishmania major
33c2wtmC_
not modelled 99.9 14 PDB header:hydrolase
Chain: C: PDB Molecule:est1e;
PDBTitle: est1e from butyrivibrio proteoclasticus
34c3iumA_
not modelled 99.9 14 PDB header:hydrolase
Chain: A: PDB Molecule:prolyl endopeptidase;
PDBTitle: appep_wtx opened state
35c1yr2A_
not modelled 99.9 15 PDB header:hydrolase
Chain: A: PDB Molecule:prolyl oligopeptidase;
PDBTitle: structural and mechanistic analysis of two prolyl endopeptidases: role2 of inter-domain dynamics in catalysis and specificity
36c1mpxB_
not modelled 99.9 15 PDB header:hydrolase
Chain: B: PDB Molecule:alpha-amino acid ester hydrolase;
PDBTitle: alpha-amino acid ester hydrolase labeled with selenomethionine
37c2vavL_
not modelled 99.9 15 PDB header:transferase
Chain: L: PDB Molecule:acetyl-coa--deacetylcephalosporin c
PDBTitle: crystal structure of deacetylcephalosporin c2 acetyltransferase (dac-soak)
38c2r11D_
not modelled 99.9 10 PDB header:hydrolase
Chain: D: PDB Molecule:carboxylesterase np;
PDBTitle: crystal structure of putative hydrolase (2632844) from2 bacillus subtilis at 1.96 a resolution
39c1cr6A_
not modelled 99.9 22 PDB header:hydrolase
Chain: A: PDB Molecule:epoxide hydrolase;
PDBTitle: crystal structure of murine soluble epoxide hydrolase2 complexed with cpu inhibitor
40d1qfma2
not modelled 99.9 14 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Prolyl oligopeptidase, C-terminal domain
41d2fuka1
not modelled 99.9 19 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Atu1826-like
42c3jw8A_
not modelled 99.9 14 PDB header:hydrolase
Chain: A: PDB Molecule:mgll protein;
PDBTitle: crystal structure of human mono-glyceride lipase
43c3llcA_
not modelled 99.9 14 PDB header:hydrolase
Chain: A: PDB Molecule:putative hydrolase;
PDBTitle: crystal structure of putative hydrolase (yp_002548124.1) from2 agrobacterium vitis s4 at 1.80 a resolution
44c3qm1A_
not modelled 99.9 15 PDB header:hydrolase
Chain: A: PDB Molecule:cinnamoyl esterase;
PDBTitle: crystal structure of the lactobacillus johnsonii cinnamoyl esterase2 lj0536 s106a mutant in complex with ethylferulate, form ii
45c3hjuB_
not modelled 99.9 13 PDB header:hydrolase
Chain: B: PDB Molecule:monoglyceride lipase;
PDBTitle: crystal structure of human monoglyceride lipase
46d2vata1
not modelled 99.9 14 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:O-acetyltransferase
47c3v48B_
not modelled 99.9 14 PDB header:hydrolase
Chain: B: PDB Molecule:putative aminoacrylate hydrolase rutd;
PDBTitle: crystal structure of the putative alpha/beta hydrolase rutd from2 e.coli
48c2y6vB_
not modelled 99.9 15 PDB header:hydrolase
Chain: B: PDB Molecule:peroxisomal membrane protein lpx1;
PDBTitle: peroxisomal alpha-beta-hydrolase lpx1 (yor084w) from2 saccharomyces cerevisiae (crystal form i)
49c3i1iA_
not modelled 99.9 14 PDB header:transferase
Chain: A: PDB Molecule:homoserine o-acetyltransferase;
PDBTitle: x-ray crystal structure of homoserine o-acetyltransferase from2 bacillus anthracis
50d1jfra_
not modelled 99.9 22 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Lipase
51c3doiA_
not modelled 99.9 19 PDB header:hydrolase
Chain: A: PDB Molecule:esterase;
PDBTitle: crystal structure of a thermostable esterase complex with2 paraoxon
52d1lnsa3
not modelled 99.9 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:PepX catalytic domain-like
53c3trdA_
not modelled 99.9 18 PDB header:hydrolase
Chain: A: PDB Molecule:alpha/beta hydrolase;
PDBTitle: structure of an alpha-beta serine hydrolase homologue from coxiella2 burnetii
54c3om8A_
not modelled 99.9 16 PDB header:hydrolase
Chain: A: PDB Molecule:probable hydrolase;
PDBTitle: the crystal structure of a hydrolase from pseudomonas aeruginosa pa01
55c3h04A_
not modelled 99.9 11 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: the crystal structure of the protein with unknown function from2 staphylococcus aureus subsp. aureus mu50
56c2q0xA_
not modelled 99.9 15 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: alpha/beta hydrolase fold protein of unknown function
57d2i3da1
not modelled 99.9 19 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Atu1826-like
58c2i3dA_
not modelled 99.9 19 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein atu1826;
PDBTitle: crystal structure of protein of unknown function atu1826, a putative2 alpha/beta hydrolase from agrobacterium tumefaciens
59c2xuaH_
not modelled 99.9 15 PDB header:hydrolase
Chain: H: PDB Molecule:3-oxoadipate enol-lactonase;
PDBTitle: crystal structure of the enol-lactonase from burkholderia2 xenovorans lb400
60d1mtza_
not modelled 99.9 20 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Proline iminopeptidase-like
61d2hu7a2
not modelled 99.9 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Acylamino-acid-releasing enzyme, C-terminal donain
62d1orva2
not modelled 99.9 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:DPP6 catalytic domain-like
63c2qruA_
not modelled 99.9 12 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of an alpha/beta hydrolase superfamily protein from2 enterococcus faecalis
64d2bgra2
not modelled 99.9 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:DPP6 catalytic domain-like
65d1ufoa_
not modelled 99.9 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Hypothetical protein TT1662
66c3bxpA_
not modelled 99.9 11 PDB header:hydrolase
Chain: A: PDB Molecule:putative lipase/esterase;
PDBTitle: crystal structure of a putative carboxylesterase (lp_2923) from2 lactobacillus plantarum wcfs1 at 1.70 a resolution
67d2b61a1
not modelled 99.9 14 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:O-acetyltransferase
68c3qvmA_
not modelled 99.9 12 PDB header:hydrolase
Chain: A: PDB Molecule:olei00960;
PDBTitle: the structure of olei00960, a hydrolase from oleispira antarctica
69c3h2iA_
not modelled 99.9 17 PDB header:hydrolase
Chain: A: PDB Molecule:esterase;
PDBTitle: crystal structure of n228w mutant of the rice cell wall2 degrading esterase lipa from xanthomonas oryzae
70c2cjpA_
not modelled 99.9 17 PDB header:hydrolase
Chain: A: PDB Molecule:epoxide hydrolase;
PDBTitle: structure of potato (solanum tuberosum) epoxide hydrolase i2 (steh1)
71c3fcxA_
not modelled 99.9 16 PDB header:hydrolase
Chain: A: PDB Molecule:s-formylglutathione hydrolase;
PDBTitle: crystal structure of human esterase d
72c3nuzF_
not modelled 99.9 17 PDB header:hydrolase
Chain: F: PDB Molecule:putative acetyl xylan esterase;
PDBTitle: crystal structure of a putative acetyl xylan esterase (bf1801) from2 bacteroides fragilis nctc 9343 at 2.30 a resolution
73c3u1tA_
not modelled 99.9 18 PDB header:hydrolase
Chain: A: PDB Molecule:dmma haloalkane dehalogenase;
PDBTitle: haloalkane dehalogenase, dmma, of marine microbial origin
74c2yysA_
not modelled 99.9 13 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:proline iminopeptidase-related protein;
PDBTitle: crystal structure of the proline iminopeptidase-related protein2 ttha1809 from thermus thermophilus hb8
75c2qmqA_
not modelled 99.9 8 PDB header:signaling protein
Chain: A: PDB Molecule:protein ndrg2;
PDBTitle: crystal structure of a n-myc downstream regulated 2 protein (ndrg2,2 syld, ndr2, ai182517, au040374) from mus musculus at 1.70 a3 resolution
76d1cr6a2
not modelled 99.9 18 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Epoxide hydrolase
77d2pl5a1
not modelled 99.9 14 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:O-acetyltransferase
78d1b6ga_
not modelled 99.9 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloalkane dehalogenase
79c2e3jA_
not modelled 99.9 14 PDB header:hydrolase
Chain: A: PDB Molecule:epoxide hydrolase ephb;
PDBTitle: the crystal structure of epoxide hydrolase b (rv1938) from2 mycobacterium tuberculosis at 2.1 angstrom
80c1lnsA_
not modelled 99.9 19 PDB header:hydrolase
Chain: A: PDB Molecule:x-prolyl dipeptidyl aminopetidase;
PDBTitle: crystal structure analysis of the x-prolyl dipeptidyl2 aminopeptidase from lactococcus lactis
81d1wm1a_
not modelled 99.9 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Proline iminopeptidase-like
82c3dyvA_
not modelled 99.9 8 PDB header:hydrolase
Chain: A: PDB Molecule:esterase d;
PDBTitle: snapshots of esterase d from lactobacillus rhamnosus:2 insights into a rotation driven catalytic mechanism
83d1a8qa_
not modelled 99.9 14 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloperoxidase
84d1q0ra_
not modelled 99.9 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Aclacinomycin methylesterase RdmC
85d1zd3a2
not modelled 99.9 18 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Epoxide hydrolase
86c3bwxA_
not modelled 99.9 15 PDB header:hydrolase
Chain: A: PDB Molecule:alpha/beta hydrolase;
PDBTitle: crystal structure of an alpha/beta hydrolase (yp_496220.1) from2 novosphingobium aromaticivorans dsm 12444 at 1.50 a resolution
87c3f67A_
not modelled 99.9 19 PDB header:hydrolase
Chain: A: PDB Molecule:putative dienelactone hydrolase;
PDBTitle: crystal structure of putative dienelactone hydrolase from klebsiella2 pneumoniae subsp. pneumoniae mgh 78578
88c3e3aA_
not modelled 99.9 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:possible peroxidase bpoc;
PDBTitle: the structure of rv0554 from mycobacterium tuberculosis
89d1dina_
not modelled 99.9 19 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Dienelactone hydrolase
90d1xfda2
not modelled 99.9 14 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:DPP6 catalytic domain-like
91c3e0xB_
not modelled 99.9 13 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:lipase-esterase related protein;
PDBTitle: the crystal structure of a lipase-esterase related protein2 from clostridium acetobutylicum atcc 824
92c3oosA_
not modelled 99.9 14 PDB header:hydrolase
Chain: A: PDB Molecule:alpha/beta hydrolase family protein;
PDBTitle: the structure of an alpha/beta fold family hydrolase from bacillus2 anthracis str. sterne
93d1azwa_
not modelled 99.9 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Proline iminopeptidase-like
94c2qjwA_
not modelled 99.9 12 PDB header:hydrolase
Chain: A: PDB Molecule:uncharacterized protein xcc1541;
PDBTitle: crystal structure of a putative hydrolase of the alpha/beta2 superfamily (xcc1541) from xanthomonas campestris pv. campestris at3 1.35 a resolution
95c2ockA_
not modelled 99.9 15 PDB header:hydrolase
Chain: A: PDB Molecule:valacyclovir hydrolase;
PDBTitle: crystal structure of valacyclovir hydrolase d123n mutant
96d1m33a_
not modelled 99.9 12 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Biotin biosynthesis protein BioH
97c3bjrA_
not modelled 99.8 16 PDB header:hydrolase
Chain: A: PDB Molecule:putative carboxylesterase;
PDBTitle: crystal structure of a putative carboxylesterase (lp_1002) from2 lactobacillus plantarum wcfs1 at 2.09 a resolution
98d1hkha_
not modelled 99.8 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloperoxidase
99c2veoA_
not modelled 99.8 14 PDB header:hydrolase
Chain: A: PDB Molecule:lipase a;
PDBTitle: x-ray structure of candida antarctica lipase a in its2 closed state.
100c3d0kA_
not modelled 99.8 17 PDB header:hydrolase
Chain: A: PDB Molecule:putative poly(3-hydroxybutyrate) depolymerase lpqc;
PDBTitle: crystal structure of the lpqc, poly(3-hydroxybutyrate) depolymerase2 from bordetella parapertussis
101c1u2eA_
not modelled 99.8 16 PDB header:hydrolase
Chain: A: PDB Molecule:2-hydroxy-6-ketonona-2,4-dienedioic acid
PDBTitle: crystal structure of the c-c bond hydrolase mhpc
102c2xt0A_
not modelled 99.8 12 PDB header:hydrolase
Chain: A: PDB Molecule:haloalkane dehalogenase;
PDBTitle: dehalogenase dppa from plesiocystis pacifica sir-i
103c2xmzA_
not modelled 99.8 11 PDB header:lyase
Chain: A: PDB Molecule:hydrolase, alpha/beta hydrolase fold family;
PDBTitle: structure of menh from s. aureus
104c3nwoA_
not modelled 99.8 12 PDB header:hydrolase
Chain: A: PDB Molecule:proline iminopeptidase;
PDBTitle: crystal structure of proline iminopeptidase mycobacterium smegmatis
105c2fx5A_
not modelled 99.8 19 PDB header:hydrolase
Chain: A: PDB Molecule:lipase;
PDBTitle: pseudomonas mendocina lipase
106d1uxoa_
not modelled 99.8 14 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:YdeN-like
107c3d59B_
not modelled 99.8 21 PDB header:hydrolase
Chain: B: PDB Molecule:platelet-activating factor acetylhydrolase;
PDBTitle: crystal structure of human plasma platelet activating2 factor acetylhydrolase
108c3ls2D_
not modelled 99.8 15 PDB header:hydrolase
Chain: D: PDB Molecule:s-formylglutathione hydrolase;
PDBTitle: crystal structure of an s-formylglutathione hydrolase from2 pseudoalteromonas haloplanktis tac125
109c1zoiC_
not modelled 99.8 16 PDB header:hydrolase
Chain: C: PDB Molecule:esterase;
PDBTitle: crystal structure of a stereoselective esterase from2 pseudomonas putida ifo12996
110c2rauA_
not modelled 99.8 17 PDB header:hydrolase
Chain: A: PDB Molecule:putative esterase;
PDBTitle: crystal structure of a putative lipase (np_343859.1) from sulfolobus2 solfataricus at 1.85 a resolution
111c3fsgC_
not modelled 99.8 13 PDB header:hydrolase
Chain: C: PDB Molecule:alpha/beta superfamily hydrolase;
PDBTitle: crystal structure of alpha/beta superfamily hydrolase from oenococcus2 oeni psu-1
112c3ed1E_
not modelled 99.8 15 PDB header:hydrolase receptor
Chain: E: PDB Molecule:gibberellin receptor gid1;
PDBTitle: crystal structure of rice gid1 complexed with ga3
113c3kdaB_
not modelled 99.8 13 PDB header:hydrolase
Chain: B: PDB Molecule:cftr inhibitory factor (cif);
PDBTitle: crystal structure of the cftr inhibitory factor cif with the h269a2 mutation
114d1a8sa_
not modelled 99.8 16 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloperoxidase
115c2vf2A_
not modelled 99.8 18 PDB header:hydrolase
Chain: A: PDB Molecule:2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate
PDBTitle: x-ray crystal structure of hsad from mycobacterium2 tuberculosis
116c3a2nF_
not modelled 99.8 14 PDB header:hydrolase
Chain: F: PDB Molecule:haloalkane dehalogenase;
PDBTitle: crystal structure of dbja (wild type type ii p21)
117d1a88a_
not modelled 99.8 15 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloperoxidase
118c3fobA_
not modelled 99.8 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:bromoperoxidase;
PDBTitle: crystal structure of bromoperoxidase from bacillus anthracis
119d2rhwa1
not modelled 99.8 16 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carbon-carbon bond hydrolase
120d1c4xa_
not modelled 99.8 15 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carbon-carbon bond hydrolase

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0