Phyre 2 Results for P76347

Email	l.a.kelley@imperial.ac.uk
Description	P76347
Date	Wed Jan 25 15:21:07 GMT 2012
Unique Job ID	7a32c338076c9d60

Summary

Top model

Image coloured by rainbow N → C terminus

Model (left) based on template c1cwvA_

Top template information

PDB header:structural protein
Chain: A: PDB Molecule:invasin;
PDBTitle: crystal structure of invasin: a bacterial integrin-binding protein

Confidence and coverage

Confidence:

100.0%

Coverage:

20%

460 residues ( 20% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.

Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.

1132 residues ( 48%) could be modelled at >90% confidence using multiple-templates.

You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M A T K K R S G E E I N D R Q I L C G M G I K L R R L T A G I C L I T Q L A F P M A A A A Q G V V N A A T Q Q P V P A Q

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence I A I A N A N T V P Y T L G A L E S A Q S V A E R F G I S V A E L R K L N Q F R T F A R G F D N V R Q G D E L D V P A Q

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ?
? ? ? ? ?
?
? ? ? ? ? ? ? ? ? ? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence V S E K K L T P P P G N S S D N L E Q Q I A S T S Q Q I G S L L A E D M N S E Q A A N M A R G W A S S Q A S G A M T D W

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210 . . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240

Sequence L S R F G T A R I T L G V D E D F S L K N S Q F D F L H P W Y E T P D N L F F S Q H T L H R T D E R T Q I N N G L G W R

Secondary structure

SS confidence

Disorder
? ? ?
? ? ?
?
?

Disorder confidence

. . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280 . . . . . . . . . 290 . . . . . . . . . 300

Sequence H F T P T W M S G I N F F F D H D L S R Y H S R A G I G A E Y W R D Y L K L S S N G Y L R L T N W R S A P E L D N D Y E

Secondary structure

SS confidence

Disorder
?
?
? ? ? ? ?

Disorder confidence

. . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350 . . . . . . . . . 360

Sequence A R P A N G W D V R A E S W L P A W P H L G G K L V Y E Q Y Y G D E V A L F D K D D R Q S N P H A I T A G L N Y T P F P

Secondary structure

SS confidence

Disorder
?
? ?
? ?
?

Disorder confidence

. . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence L M T F S A E Q R Q G K Q G E N D T R F A V D F T W Q P G S A M Q K Q L D P N E V A A R R S L A G S R Y D L V D R N N N

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480

Sequence I V L E Y R K K E L V R L T L T D P V T G K S G E V K S L V S S L Q T K Y A L K G Y N V E A T A L E A A G G K V V T T G

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ?
? ?
? ? ? ? ? ? ? ?
? ?

Disorder confidence

. . . . . . . . . 490 . . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540

Sequence K D I L V T L P A Y R F T S T P E T D N T W P I E V T A E D V K G N L S N R E Q S M V V V Q A P T L S Q K D S S V S L S

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 550 . . . . . . . . . 560 . . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600

Sequence T Q T L N A D S H S T A T L T F I A H D A A G N P V V G L V L S T R H E G V Q D I T L S D W K D N G D G S Y T Q I L T T

Secondary structure

SS confidence

Disorder
? ? ? ?
?

Disorder confidence

. . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630 . . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660

Sequence G A M S G T L T L M P Q L N G V D A A K A P A V V N I I S V S S S R T H S S I K I D K D R Y L S G N P I E V T V E L R D

Secondary structure

SS confidence

Disorder
?
? ? ? ? ? ? ?
? ?
?
? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700 . . . . . . . . . 710 . . . . . . . . . 720

Sequence E N D K P V K E Q K Q Q L N N A V S I D N V K P G V T T D W K E T A D G V Y K A T Y T A Y T K G S G L T A K L L M Q N W

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ?
? ? ? ? ? ?
? ? ?

Disorder confidence

. . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770 . . . . . . . . . 780

Sequence N E D L H T A G F I I D A N P Q S A K I A T L S A S N N G V L A N E N A A N T V S V N V A D E G S N P I N D H T V T F A

Secondary structure

SS confidence

Disorder ? ? ? ? ?
? ?
?
?
?

Disorder confidence

. . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence V L S G S A T S F N N Q N T A K T D V N G L A T F D L K S S K Q E D N T V E V T L E N G V K Q T L I V S F V G D S S T A

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ?
?
?
?
? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900

Sequence Q V D L Q K S K N E V V A D G N D S V T M T A T V R D A K G N L L N D V M V T F N V N S A E A K L S Q T E V N S H D G I

Secondary structure

SS confidence

Disorder ?
? ?
? ? ? ? ?
?
? ?
? ? ? ? ? ?
?
?

Disorder confidence

. . . . . . . . . 910 . . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960

Sequence A T A T L T S L K N G D Y R V T A S V S S G S Q A N Q Q V N F I G D Q S T A A L T L S V P S G D I T V T N T A P Q Y M T

Secondary structure

SS confidence

Disorder
? ? ?
?
? ? ?
? ? ? ?
?

Disorder confidence

. . . . . . . . . 970 . . . . . . . . . 980 . . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020

Sequence A T L Q D K N G N P L K D K E I T F S V P N D V A S K F S I S N G G K G M T D S N G V A I A S L T G T L A G T H M I M A

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ? ? ? ? ?
?
?

Disorder confidence

. . . . . . . . . 1030 . . . . . . . . . 1040 . . . . . . . . . 1050 . . . . . . . . . 1060 . . . . . . . . . 1070 . . . . . . . . . 1080

Sequence R L A N S N V S D A Q P M T F V A D K D R A V V V L Q T S K A E I I G N G V D E T T L T A T V K D P S N H P V A G I T V

Secondary structure

SS confidence

Disorder
? ? ? ? ?
?
? ? ? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 1090 . . . . . . . . . 1100 . . . . . . . . . 1110 . . . . . . . . . 1120 . . . . . . . . . 1130 . . . . . . . . . 1140

Sequence N F T M P Q D V A A N F T L E N N G I A I T Q A N G E A H V T L K G K K A G T H T V T A T L G N N N T S D S Q P V T F V

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ?

Disorder confidence

. . . . . . . . . 1150 . . . . . . . . . 1160 . . . . . . . . . 1170 . . . . . . . . . 1180 . . . . . . . . . 1190 . . . . . . . . . 1200

Sequence A D K A S A Q V V L Q I S K D E I T G N G V D S A T L T A T V K D Q F D N E V N N L P V T F S S A S S G L T L T P G V S

Secondary structure

SS confidence

Disorder
? ? ? ?
? ?
? ? ?
?

Disorder confidence

. . . . . . . . . 1210 . . . . . . . . . 1220 . . . . . . . . . 1230 . . . . . . . . . 1240 . . . . . . . . . 1250 . . . . . . . . . 1260

Sequence N T N E S G I A Q A T L A G V A F G E K T V T A S L A N N G A S D N K T V H F I G D T A A A K I I E L A P V P D S I I A

Secondary structure

SS confidence

Disorder ? ?
?
?
? ?
?
? ?
? ?

Disorder confidence

. . . . . . . . . 1270 . . . . . . . . . 1280 . . . . . . . . . 1290 . . . . . . . . . 1300 . . . . . . . . . 1310 . . . . . . . . . 1320

Sequence G T P Q N S S G S V I T A T V V D N N G F P V K G V T V N F T S N A A T A E M T N G G Q A V T N E Q G K A T V T Y T N T

Secondary structure

SS confidence

Disorder
?
? ? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 1330 . . . . . . . . . 1340 . . . . . . . . . 1350 . . . . . . . . . 1360 . . . . . . . . . 1370 . . . . . . . . . 1380

Sequence R S S I E S G A R P D T V E A S L E N G S S T L S T S I N V N A D A S T A H L T L L Q A L F D T V S A G E T T S L Y I E

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ?
?
? ?
? ?
? ?
? ? ? ? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 1390 . . . . . . . . . 1400 . . . . . . . . . 1410 . . . . . . . . . 1420 . . . . . . . . . 1430 . . . . . . . . . 1440

Sequence V K D N Y G N G V P Q Q E V T L S V S P S E G V T P S N N A I Y T T N H D G N F Y A S F T A T K A G V Y Q L T A T L E N

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 1450 . . . . . . . . . 1460 . . . . . . . . . 1470 . . . . . . . . . 1480 . . . . . . . . . 1490 . . . . . . . . . 1500

Sequence G D S M Q Q T V T Y V P N V A N A E I T L A A S K D P V I A D N N D L T T L T A T V A D T E G N A I A N T E V T F T L P

Secondary structure

SS confidence

Disorder ? ? ? ? ?
?
?
?
? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 1510 . . . . . . . . . 1520 . . . . . . . . . 1530 . . . . . . . . . 1540 . . . . . . . . . 1550 . . . . . . . . . 1560

Sequence E D V K A N F T L S D G G K V I T D A E G K A K V T L K G T K A G A H T V T A S M T G G K S E Q L V V N F I A D T L T A

Secondary structure

SS confidence

Disorder
? ? ? ?
? ? ? ? ?
? ? ? ?
? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 1570 . . . . . . . . . 1580 . . . . . . . . . 1590 . . . . . . . . . 1600 . . . . . . . . . 1610 . . . . . . . . . 1620

Sequence Q V N L N V T E D N F I A N N V G M T R L Q A T V T D G N G N P L A N E A V T F T L P A D V S A S F T L G Q G G S A I T

Secondary structure

SS confidence

Disorder ? ?
? ? ? ? ? ? ? ? ? ?
? ?
?
? ?

Disorder confidence

. . . . . . . . . 1630 . . . . . . . . . 1640 . . . . . . . . . 1650 . . . . . . . . . 1660 . . . . . . . . . 1670 . . . . . . . . . 1680

Sequence D I N G K A E V T L S G T K S G T Y P V T V S V N N Y G V S D T K Q V T L I A D A G T A K L A S L T S V Y S F V V S T T

Secondary structure

SS confidence

Disorder
?
? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 1690 . . . . . . . . . 1700 . . . . . . . . . 1710 . . . . . . . . . 1720 . . . . . . . . . 1730 . . . . . . . . . 1740

Sequence E G A T M T A S V T D A N G N P V E G I K V N F R G T S V T L S S T S V E T D D R G F A E I L V T S T E V G L K T V S A

Secondary structure

SS confidence

Disorder
? ? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 1750 . . . . . . . . . 1760 . . . . . . . . . 1770 . . . . . . . . . 1780 . . . . . . . . . 1790 . . . . . . . . . 1800

Sequence S L A D K P T E V I S R L L N A S A D V N S A T I T S L E I P E G Q V M V A Q D V A V K A H V N D Q F G N P V A H Q P V

Secondary structure

SS confidence

Disorder
? ?
?
? ?
? ? ?
? ? ? ? ? ? ? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 1810 . . . . . . . . . 1820 . . . . . . . . . 1830 . . . . . . . . . 1840 . . . . . . . . . 1850 . . . . . . . . . 1860

Sequence T F S A E P S S Q M I I S Q N T V S T N T Q G V A E V T M T P E R N G S Y M V K A S L P N G A S L E K Q L E A I D E K L

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ?
?
? ? ? ?

Disorder confidence

. . . . . . . . . 1870 . . . . . . . . . 1880 . . . . . . . . . 1890 . . . . . . . . . 1900 . . . . . . . . . 1910 . . . . . . . . . 1920

Sequence T L T A S S P L I G V Y A P T G A T L T A T L T S A N G T P V E G Q V I N F S V T P E G A T L S G G K V R T N S S G Q A

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ?
?
? ? ? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 1930 . . . . . . . . . 1940 . . . . . . . . . 1950 . . . . . . . . . 1960 . . . . . . . . . 1970 . . . . . . . . . 1980

Sequence P V V L T S N K V G T Y T V T A S F H N G V T I Q T Q T T V K V T G N S S T A H V A S F I A D P S T I A A T N T D L S T

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ?
? ? ?
? ?
?
? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 1990 . . . . . . . . . 2000 . . . . . . . . . 2010 . . . . . . . . . 2020 . . . . . . . . . 2030 . . . . . . . . . 2040

Sequence L K A T V E D G S G N L I E G L T V Y F A L K S G S A T L T S L T A V T D Q N G I A T T S V K G A M T G S V T V S A V T

Secondary structure

SS confidence

Disorder
?
?
? ? ? ? ? ?
?
?
?
? ? ? ? ?

Disorder confidence

. . . . . . . . . 2050 . . . . . . . . . 2060 . . . . . . . . . 2070 . . . . . . . . . 2080 . . . . . . . . . 2090 . . . . . . . . . 2100

Sequence T A G G M Q T V D I T L V A G P A D T S Q S V L K S N R S S L K G D Y T D S A E L R L V L H D I S G N P I K V S E G M E

Secondary structure

SS confidence

Disorder ? ? ?
?
? ? ? ? ? ? ? ? ? ? ?
? ?

Disorder confidence

. . . . . . . . . 2110 . . . . . . . . . 2120 . . . . . . . . . 2130 . . . . . . . . . 2140 . . . . . . . . . 2150 . . . . . . . . . 2160

Sequence F V Q S G T N V P Y I K I S A I D Y S L N I N G D Y K A T V T G G G E G I A T L I P V L N G V H Q A G L S T T I Q F T R

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ?
? ? ? ? ? ?
? ?
? ? ? ?
?

Disorder confidence

. . . . . . . . . 2170 . . . . . . . . . 2180 . . . . . . . . . 2190 . . . . . . . . . 2200 . . . . . . . . . 2210 . . . . . . . . . 2220

Sequence A E D K I M S G T V S V N G T D L P T T T F P S Q G F T G A Y Y Q L N N D N F A P G K T A A D Y E F S S S A S W V D V D

Secondary structure

SS confidence

Disorder ? ? ? ? ?
? ? ?
? ? ?

Disorder confidence

. . . . . . . . . 2230 . . . . . . . . . 2240 . . . . . . . . . 2250 . . . . . . . . . 2260 . . . . . . . . . 2270 . . . . . . . . . 2280

Sequence A T G K V T F K N V G S N S E R I T A T P K S G G P S Y V Y E I R V K S W W V N A G E A F M I Y S L A E N F C S S N G Y

Secondary structure

SS confidence

Disorder
?
?
?
? ? ? ? ?
? ?
?
?

Disorder confidence

. . . . . . . . . 2290 . . . . . . . . . 2300 . . . . . . . . . 2310 . . . . . . . . . 2320 . . . . . . . . . 2330 . . . . . . . . . 2340

Sequence T L P R A N Y L N H C S S R G I G S L Y S E W G D M G H Y T T D A G F Q S N M Y W S S S P A N S S E Q Y V V S L A T G D

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ?
?
?
? ? ?
? ?

Disorder confidence

. . . . . . . . . 2350 . . . . . . . .

Sequence Q S V F E K L G F A Y A T C Y K N L

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ?
? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered

Alpha helix

Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 1cwv chain A

Region: 1859 - 2340
Aligned: 460
Modelled: 460
Confidence: 100.0%
Identity: 23%
PDB header:structural protein
Chain: A: PDB Molecule:invasin;
PDBTitle: crystal structure of invasin: a bacterial integrin-binding protein

Phyre2

PDB 1e5u chain I

Region: 2164 - 2356
Aligned: 178
Modelled: 178
Confidence: 99.9%
Identity: 23%
PDB header:intimin
Chain: I: PDB Molecule:intimin;
PDBTitle: nmr representative structure of intimin-190 (int190) from2 enteropathogenic e. coli

Phyre2

PDB 1f00 chain I

Region: 2059 - 2356
Aligned: 275
Modelled: 275
Confidence: 99.6%
Identity: 18%
PDB header:cell adhesion
Chain: I: PDB Molecule:intimin;
PDBTitle: crystal structure of c-terminal 282-residue fragment of2 enteropathogenic e. coli intimin

Phyre2

PDB 1cwv chain A domain 4

Region: 2170 - 2253
Aligned: 82
Modelled: 82
Confidence: 98.8%
Identity: 34%
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Invasin/intimin cell-adhesion fragments
Family: Invasin/intimin cell-adhesion fragments

Phyre2

PDB 2l9y chain A

Region: 43 - 134
Aligned: 88
Modelled: 88
Confidence: 98.0%
Identity: 14%
PDB header:sugar binding protein
Chain: A: PDB Molecule:cvnh-lysm lectin;
PDBTitle: solution structure of the mocvnh-lysm module from the rice blast2 fungus magnaporthe oryzae protein (mgg_03307)

Phyre2

PDB 2djp chain A

Region: 58 - 134
Aligned: 73
Modelled: 73
Confidence: 98.0%
Identity: 12%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein sb145;
PDBTitle: the solution structure of the lysm domain of human2 hypothetical protein sb145

Phyre2

PDB 1e0g chain A

Region: 67 - 120
Aligned: 48
Modelled: 48
Confidence: 97.8%
Identity: 25%
Fold: LysM domain
Superfamily: LysM domain
Family: LysM domain

Phyre2

PDB 1cwv chain A domain 3

Region: 527 - 628
Aligned: 100
Modelled: 100
Confidence: 97.7%
Identity: 22%
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Invasin/intimin cell-adhesion fragments
Family: Invasin/intimin cell-adhesion fragments

Phyre2

PDB 1cwv chain A domain 2

Region: 529 - 628
Aligned: 96
Modelled: 96
Confidence: 97.5%
Identity: 23%
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Invasin/intimin cell-adhesion fragments
Family: Invasin/intimin cell-adhesion fragments

Phyre2

PDB 2zfg chain A domain 1

Region: 228 - 388
Aligned: 157
Modelled: 157
Confidence: 97.5%
Identity: 12%
Fold: Transmembrane beta-barrels
Superfamily: Porins
Family: Porin

Phyre2

PDB 1y7m chain A domain 2

Region: 69 - 118
Aligned: 45
Modelled: 45
Confidence: 97.5%
Identity: 24%
Fold: LysM domain
Superfamily: LysM domain
Family: LysM domain

Phyre2

PDB 1pho chain A

Region: 201 - 388
Aligned: 178
Modelled: 178
Confidence: 97.3%
Identity: 13%
Fold: Transmembrane beta-barrels
Superfamily: Porins
Family: Porin

Phyre2

PDB 1cwv chain A domain 5

Region: 2258 - 2340
Aligned: 79
Modelled: 79
Confidence: 97.2%
Identity: 23%
Fold: C-type lectin-like
Superfamily: C-type lectin-like
Family: Invasin/intimin cell-adhesion fragment, C-terminal domain

Phyre2

PDB 2gu1 chain A

Region: 69 - 124
Aligned: 56
Modelled: 56
Confidence: 97.0%
Identity: 14%
PDB header:hydrolase
Chain: A: PDB Molecule:zinc peptidase;
PDBTitle: crystal structure of a zinc containing peptidase from2 vibrio cholerae

Phyre2

PDB 3nb3 chain C

Region: 227 - 389
Aligned: 132
Modelled: 132
Confidence: 96.8%
Identity: 19%
PDB header:virus
Chain: C: PDB Molecule:outer membrane protein a;
PDBTitle: the host outer membrane proteins ompa and ompc are packed at specific2 sites in the shigella phage sf6 virion as structural components

Phyre2

PDB 2qom chain B

Region: 184 - 389
Aligned: 202
Modelled: 202
Confidence: 96.8%
Identity: 11%
PDB header:hydrolase
Chain: B: PDB Molecule:serine protease espp;
PDBTitle: the crystal structure of the e.coli espp autotransporter beta-domain.

Phyre2

PDB 2k0l chain A

Region: 233 - 391
Aligned: 149
Modelled: 149
Confidence: 96.6%
Identity: 19%
PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane protein a;
PDBTitle: nmr structure of the transmembrane domain of the outer2 membrane protein a from klebsiella pneumoniae in dhpc3 micelles.

Phyre2

PDB 1cwv chain A domain 1

Region: 841 - 933
Aligned: 92
Modelled: 92
Confidence: 96.5%
Identity: 25%
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Invasin/intimin cell-adhesion fragments
Family: Invasin/intimin cell-adhesion fragments

Phyre2

PDB 3aeh chain B

Region: 184 - 390
Aligned: 182
Modelled: 182
Confidence: 96.5%
Identity: 9%
PDB header:hydrolase
Chain: B: PDB Molecule:hemoglobin-binding protease hbp autotransporter;
PDBTitle: integral membrane domain of autotransporter hbp

Phyre2

PDB 1osm chain A

Region: 243 - 388
Aligned: 137
Modelled: 137
Confidence: 96.4%
Identity: 18%
Fold: Transmembrane beta-barrels
Superfamily: Porins
Family: Porin

Phyre2

PDB 1f00 chain I domain 1

Region: 738 - 835
Aligned: 93
Modelled: 93
Confidence: 96.1%
Identity: 27%
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Invasin/intimin cell-adhesion fragments
Family: Invasin/intimin cell-adhesion fragments

Phyre2

PDB 3pdg chain A

Region: 430 - 526
Aligned: 86
Modelled: 86
Confidence: 95.9%
Identity: 13%
PDB header:unknown function
Chain: A: PDB Molecule:fibronectin(iii)-like module;
PDBTitle: structures of clostridium thermocellum cbha fibronectin(iii)-like2 modules

Phyre2

PDB 3pe9 chain C

Region: 430 - 529
Aligned: 88
Modelled: 88
Confidence: 95.0%
Identity: 15%
PDB header:unknown function
Chain: C: PDB Molecule:fibronectin(iii)-like module;
PDBTitle: structures of clostridium thermocellum cbha fibronectin(iii)-like2 modules

Phyre2

PDB 3pe9 chain A

Region: 430 - 529
Aligned: 88
Modelled: 88
Confidence: 95.0%
Identity: 15%
PDB header:unknown function
Chain: A: PDB Molecule:fibronectin(iii)-like module;
PDBTitle: structures of clostridium thermocellum cbha fibronectin(iii)-like2 modules

Phyre2

PDB 2bpd chain B

Region: 2255 - 2358
Aligned: 100
Modelled: 100
Confidence: 70.7%
Identity: 17%
PDB header:receptor
Chain: B: PDB Molecule:dectin-1;
PDBTitle: structure of murine dectin-1

Phyre2

PDB 2c5u chain A

Region: 413 - 442
Aligned: 30
Modelled: 29
Confidence: 51.7%
Identity: 30%
PDB header:ligase
Chain: A: PDB Molecule:rna ligase;
PDBTitle: t4 rna ligase (rnl1) crystal structure

Phyre2

100

101

102

103

104

105

106

107

108

c2c5uA_

109

110

111

112

113

114

115

116

117

118

119

120

121

122

123

124

125

126

127

128

129

130

131

132

133

134

135

136

137

138

139

140

141

142

143

144

145

146

147

148

149

150

151

152

153

154

155

156

157

158

159

160

161

162

163

164

165

166

167

168

169

170

171

172

173

174

175

176

177

178

179

180

181

182

183

184

185

186

187

188

189

190

191

192

193

194

195

196

197

198

199

200

201

202

203

204

205

206

207

208

209

210

211

212

213

214

215

216

217

218

219

220

221

222

223

224

225

226

227

228

229

230

Detailed template information

#	Template	Alignment Coverage	3D Model	Confidence	% i.d.	Template Information

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server

Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]

If you use the binding site predictions from 3DLigandSite, please also cite:

3DLigandSite: predicting ligand-binding sites using similar structures.

Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]

Imperial College London

Lawrence Kelley, Benjamin Jefferys

Disclaimer

Terms and Conditions

Component software

Template detection: HHpred 1.51

Secondary structure prediction: Psi-pred 2.5

Disorder prediction: Disopred 2.4

Transmembrane prediction: Memsat_SVM

Multi-template modelling and ab initio: Poing 1.0

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence	M	A	T	K	K	R	S	G	E	E	I	N	D	R	Q	I	L	C	G	M	G	I	K	L	R	R	L	T	A	G	I	C	L	I	T	Q	L	A	F	P	M	A	A	A	A	Q	G	V	V	N	A	A	T	Q	Q	P	V	P	A	Q
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?																										?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence	I	A	I	A	N	A	N	T	V	P	Y	T	L	G	A	L	E	S	A	Q	S	V	A	E	R	F	G	I	S	V	A	E	L	R	K	L	N	Q	F	R	T	F	A	R	G	F	D	N	V	R	Q	G	D	E	L	D	V	P	A	Q
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?	?	?	?					?	?	?	?	?								?												?	?	?	?	?	?	?	?	?	?	?	?	?	?									?
Disorder confidence

	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence	V	S	E	K	K	L	T	P	P	P	G	N	S	S	D	N	L	E	Q	Q	I	A	S	T	S	Q	Q	I	G	S	L	L	A	E	D	M	N	S	E	Q	A	A	N	M	A	R	G	W	A	S	S	Q	A	S	G	A	M	T	D	W
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence	L	S	R	F	G	T	A	R	I	T	L	G	V	D	E	D	F	S	L	K	N	S	Q	F	D	F	L	H	P	W	Y	E	T	P	D	N	L	F	F	S	Q	H	T	L	H	R	T	D	E	R	T	Q	I	N	N	G	L	G	W	R
Secondary structure
SS confidence
Disorder													?	?	?			?	?	?		?																									?
Disorder confidence

	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence	H	F	T	P	T	W	M	S	G	I	N	F	F	F	D	H	D	L	S	R	Y	H	S	R	A	G	I	G	A	E	Y	W	R	D	Y	L	K	L	S	S	N	G	Y	L	R	L	T	N	W	R	S	A	P	E	L	D	N	D	Y	E
Secondary structure
SS confidence
Disorder																							?																													?		?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence	A	R	P	A	N	G	W	D	V	R	A	E	S	W	L	P	A	W	P	H	L	G	G	K	L	V	Y	E	Q	Y	Y	G	D	E	V	A	L	F	D	K	D	D	R	Q	S	N	P	H	A	I	T	A	G	L	N	Y	T	P	F	P
Secondary structure
SS confidence
Disorder			?																																				?	?		?	?		?
Disorder confidence

	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	L	M	T	F	S	A	E	Q	R	Q	G	K	Q	G	E	N	D	T	R	F	A	V	D	F	T	W	Q	P	G	S	A	M	Q	K	Q	L	D	P	N	E	V	A	A	R	R	S	L	A	G	S	R	Y	D	L	V	D	R	N	N	N
Secondary structure
SS confidence
Disorder						?	?	?	?	?	?	?	?	?	?	?	?	?																						?	?	?	?	?	?	?	?	?	?	?	?			?
Disorder confidence

	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence	I	V	L	E	Y	R	K	K	E	L	V	R	L	T	L	T	D	P	V	T	G	K	S	G	E	V	K	S	L	V	S	S	L	Q	T	K	Y	A	L	K	G	Y	N	V	E	A	T	A	L	E	A	A	G	G	K	V	V	T	T	G
Secondary structure
SS confidence
Disorder																	?	?	?	?	?	?	?	?	?									?	?												?	?	?	?	?	?	?	?			?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence	K	D	I	L	V	T	L	P	A	Y	R	F	T	S	T	P	E	T	D	N	T	W	P	I	E	V	T	A	E	D	V	K	G	N	L	S	N	R	E	Q	S	M	V	V	V	Q	A	P	T	L	S	Q	K	D	S	S	V	S	L	S
Secondary structure
SS confidence
Disorder											?	?	?	?	?	?	?	?	?	?																											?	?	?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence	T	Q	T	L	N	A	D	S	H	S	T	A	T	L	T	F	I	A	H	D	A	A	G	N	P	V	V	G	L	V	L	S	T	R	H	E	G	V	Q	D	I	T	L	S	D	W	K	D	N	G	D	G	S	Y	T	Q	I	L	T	T
Secondary structure
SS confidence
Disorder																																				?	?	?	?		?
Disorder confidence

	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660
Sequence	G	A	M	S	G	T	L	T	L	M	P	Q	L	N	G	V	D	A	A	K	A	P	A	V	V	N	I	I	S	V	S	S	S	R	T	H	S	S	I	K	I	D	K	D	R	Y	L	S	G	N	P	I	E	V	T	V	E	L	R	D
Secondary structure
SS confidence
Disorder				?									?	?	?	?	?	?	?												?	?		?									?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720
Sequence	E	N	D	K	P	V	K	E	Q	K	Q	Q	L	N	N	A	V	S	I	D	N	V	K	P	G	V	T	T	D	W	K	E	T	A	D	G	V	Y	K	A	T	Y	T	A	Y	T	K	G	S	G	L	T	A	K	L	L	M	Q	N	W
Secondary structure
SS confidence
Disorder																		?	?	?	?	?	?	?	?																					?	?	?	?	?	?							?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780
Sequence	N	E	D	L	H	T	A	G	F	I	I	D	A	N	P	Q	S	A	K	I	A	T	L	S	A	S	N	N	G	V	L	A	N	E	N	A	A	N	T	V	S	V	N	V	A	D	E	G	S	N	P	I	N	D	H	T	V	T	F	A
Secondary structure
SS confidence
Disorder	?	?	?	?	?																						?	?		?																	?			?
Disorder confidence

	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	V	L	S	G	S	A	T	S	F	N	N	Q	N	T	A	K	T	D	V	N	G	L	A	T	F	D	L	K	S	S	K	Q	E	D	N	T	V	E	V	T	L	E	N	G	V	K	Q	T	L	I	V	S	F	V	G	D	S	S	T	A
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?	?	?	?																?		?														?										?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900
Sequence	Q	V	D	L	Q	K	S	K	N	E	V	V	A	D	G	N	D	S	V	T	M	T	A	T	V	R	D	A	K	G	N	L	L	N	D	V	M	V	T	F	N	V	N	S	A	E	A	K	L	S	Q	T	E	V	N	S	H	D	G	I
Secondary structure
SS confidence
Disorder	?			?	?		?	?	?	?	?		?																	?	?													?	?	?	?	?	?				?		?
Disorder confidence

	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960
Sequence	A	T	A	T	L	T	S	L	K	N	G	D	Y	R	V	T	A	S	V	S	S	G	S	Q	A	N	Q	Q	V	N	F	I	G	D	Q	S	T	A	A	L	T	L	S	V	P	S	G	D	I	T	V	T	N	T	A	P	Q	Y	M	T
Secondary structure
SS confidence
Disorder																							?	?	?									?		?	?	?							?	?	?	?					?
Disorder confidence

	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020
Sequence	A	T	L	Q	D	K	N	G	N	P	L	K	D	K	E	I	T	F	S	V	P	N	D	V	A	S	K	F	S	I	S	N	G	G	K	G	M	T	D	S	N	G	V	A	I	A	S	L	T	G	T	L	A	G	T	H	M	I	M	A
Secondary structure
SS confidence
Disorder																							?	?	?	?	?	?	?	?	?	?	?	?	?	?		?																?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080
Sequence	R	L	A	N	S	N	V	S	D	A	Q	P	M	T	F	V	A	D	K	D	R	A	V	V	V	L	Q	T	S	K	A	E	I	I	G	N	G	V	D	E	T	T	L	T	A	T	V	K	D	P	S	N	H	P	V	A	G	I	T	V
Secondary structure
SS confidence
Disorder					?	?	?	?	?												?								?	?	?	?	?	?	?																		?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140
Sequence	N	F	T	M	P	Q	D	V	A	A	N	F	T	L	E	N	N	G	I	A	I	T	Q	A	N	G	E	A	H	V	T	L	K	G	K	K	A	G	T	H	T	V	T	A	T	L	G	N	N	N	T	S	D	S	Q	P	V	T	F	V
Secondary structure
SS confidence
Disorder							?	?	?	?	?	?	?	?	?	?	?	?	?																														?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.	.	.	.	.	1180	.	.	.	.	.	.	.	.	.	1190	.	.	.	.	.	.	.	.	.	1200
Sequence	A	D	K	A	S	A	Q	V	V	L	Q	I	S	K	D	E	I	T	G	N	G	V	D	S	A	T	L	T	A	T	V	K	D	Q	F	D	N	E	V	N	N	L	P	V	T	F	S	S	A	S	S	G	L	T	L	T	P	G	V	S
Secondary structure
SS confidence
Disorder														?	?	?	?		?	?																															?	?	?							?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1210	.	.	.	.	.	.	.	.	.	1220	.	.	.	.	.	.	.	.	.	1230	.	.	.	.	.	.	.	.	.	1240	.	.	.	.	.	.	.	.	.	1250	.	.	.	.	.	.	.	.	.	1260
Sequence	N	T	N	E	S	G	I	A	Q	A	T	L	A	G	V	A	F	G	E	K	T	V	T	A	S	L	A	N	N	G	A	S	D	N	K	T	V	H	F	I	G	D	T	A	A	A	K	I	I	E	L	A	P	V	P	D	S	I	I	A
Secondary structure
SS confidence
Disorder	?	?														?		?												?	?															?				?	?			?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1270	.	.	.	.	.	.	.	.	.	1280	.	.	.	.	.	.	.	.	.	1290	.	.	.	.	.	.	.	.	.	1300	.	.	.	.	.	.	.	.	.	1310	.	.	.	.	.	.	.	.	.	1320
Sequence	G	T	P	Q	N	S	S	G	S	V	I	T	A	T	V	V	D	N	N	G	F	P	V	K	G	V	T	V	N	F	T	S	N	A	A	T	A	E	M	T	N	G	G	Q	A	V	T	N	E	Q	G	K	A	T	V	T	Y	T	N	T
Secondary structure
SS confidence
Disorder					?																													?	?	?	?	?	?		?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1330	.	.	.	.	.	.	.	.	.	1340	.	.	.	.	.	.	.	.	.	1350	.	.	.	.	.	.	.	.	.	1360	.	.	.	.	.	.	.	.	.	1370	.	.	.	.	.	.	.	.	.	1380
Sequence	R	S	S	I	E	S	G	A	R	P	D	T	V	E	A	S	L	E	N	G	S	S	T	L	S	T	S	I	N	V	N	A	D	A	S	T	A	H	L	T	L	L	Q	A	L	F	D	T	V	S	A	G	E	T	T	S	L	Y	I	E
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?	?																?							?	?		?	?		?	?					?	?	?	?	?	?	?	?		?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1390	.	.	.	.	.	.	.	.	.	1400	.	.	.	.	.	.	.	.	.	1410	.	.	.	.	.	.	.	.	.	1420	.	.	.	.	.	.	.	.	.	1430	.	.	.	.	.	.	.	.	.	1440
Sequence	V	K	D	N	Y	G	N	G	V	P	Q	Q	E	V	T	L	S	V	S	P	S	E	G	V	T	P	S	N	N	A	I	Y	T	T	N	H	D	G	N	F	Y	A	S	F	T	A	T	K	A	G	V	Y	Q	L	T	A	T	L	E	N
Secondary structure
SS confidence
Disorder																				?	?	?	?	?	?	?	?	?	?																			?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1450	.	.	.	.	.	.	.	.	.	1460	.	.	.	.	.	.	.	.	.	1470	.	.	.	.	.	.	.	.	.	1480	.	.	.	.	.	.	.	.	.	1490	.	.	.	.	.	.	.	.	.	1500
Sequence	G	D	S	M	Q	Q	T	V	T	Y	V	P	N	V	A	N	A	E	I	T	L	A	A	S	K	D	P	V	I	A	D	N	N	D	L	T	T	L	T	A	T	V	A	D	T	E	G	N	A	I	A	N	T	E	V	T	F	T	L	P
Secondary structure
SS confidence
Disorder	?	?	?	?	?					?				?			?							?	?	?	?	?		?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1510	.	.	.	.	.	.	.	.	.	1520	.	.	.	.	.	.	.	.	.	1530	.	.	.	.	.	.	.	.	.	1540	.	.	.	.	.	.	.	.	.	1550	.	.	.	.	.	.	.	.	.	1560
Sequence	E	D	V	K	A	N	F	T	L	S	D	G	G	K	V	I	T	D	A	E	G	K	A	K	V	T	L	K	G	T	K	A	G	A	H	T	V	T	A	S	M	T	G	G	K	S	E	Q	L	V	V	N	F	I	A	D	T	L	T	A
Secondary structure
SS confidence
Disorder		?	?	?	?				?	?	?	?	?																															?	?	?	?								?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1570	.	.	.	.	.	.	.	.	.	1580	.	.	.	.	.	.	.	.	.	1590	.	.	.	.	.	.	.	.	.	1600	.	.	.	.	.	.	.	.	.	1610	.	.	.	.	.	.	.	.	.	1620
Sequence	Q	V	N	L	N	V	T	E	D	N	F	I	A	N	N	V	G	M	T	R	L	Q	A	T	V	T	D	G	N	G	N	P	L	A	N	E	A	V	T	F	T	L	P	A	D	V	S	A	S	F	T	L	G	Q	G	G	S	A	I	T
Secondary structure
SS confidence
Disorder	?	?			?	?	?	?	?	?	?	?	?	?																																		?	?		?		?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1630	.	.	.	.	.	.	.	.	.	1640	.	.	.	.	.	.	.	.	.	1650	.	.	.	.	.	.	.	.	.	1660	.	.	.	.	.	.	.	.	.	1670	.	.	.	.	.	.	.	.	.	1680
Sequence	D	I	N	G	K	A	E	V	T	L	S	G	T	K	S	G	T	Y	P	V	T	V	S	V	N	N	Y	G	V	S	D	T	K	Q	V	T	L	I	A	D	A	G	T	A	K	L	A	S	L	T	S	V	Y	S	F	V	V	S	T	T
Secondary structure
SS confidence
Disorder																												?													?	?	?	?	?	?		?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1690	.	.	.	.	.	.	.	.	.	1700	.	.	.	.	.	.	.	.	.	1710	.	.	.	.	.	.	.	.	.	1720	.	.	.	.	.	.	.	.	.	1730	.	.	.	.	.	.	.	.	.	1740
Sequence	E	G	A	T	M	T	A	S	V	T	D	A	N	G	N	P	V	E	G	I	K	V	N	F	R	G	T	S	V	T	L	S	S	T	S	V	E	T	D	D	R	G	F	A	E	I	L	V	T	S	T	E	V	G	L	K	T	V	S	A
Secondary structure
SS confidence
Disorder																													?	?	?	?	?	?				?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1750	.	.	.	.	.	.	.	.	.	1760	.	.	.	.	.	.	.	.	.	1770	.	.	.	.	.	.	.	.	.	1780	.	.	.	.	.	.	.	.	.	1790	.	.	.	.	.	.	.	.	.	1800
Sequence	S	L	A	D	K	P	T	E	V	I	S	R	L	L	N	A	S	A	D	V	N	S	A	T	I	T	S	L	E	I	P	E	G	Q	V	M	V	A	Q	D	V	A	V	K	A	H	V	N	D	Q	F	G	N	P	V	A	H	Q	P	V
Secondary structure
SS confidence
Disorder					?	?		?								?	?		?	?	?						?	?	?	?	?	?	?	?	?	?	?																?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1810	.	.	.	.	.	.	.	.	.	1820	.	.	.	.	.	.	.	.	.	1830	.	.	.	.	.	.	.	.	.	1840	.	.	.	.	.	.	.	.	.	1850	.	.	.	.	.	.	.	.	.	1860
Sequence	T	F	S	A	E	P	S	S	Q	M	I	I	S	Q	N	T	V	S	T	N	T	Q	G	V	A	E	V	T	M	T	P	E	R	N	G	S	Y	M	V	K	A	S	L	P	N	G	A	S	L	E	K	Q	L	E	A	I	D	E	K	L
Secondary structure
SS confidence
Disorder							?	?	?	?	?	?	?	?	?	?	?	?																												?	?	?	?	?				?		?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1870	.	.	.	.	.	.	.	.	.	1880	.	.	.	.	.	.	.	.	.	1890	.	.	.	.	.	.	.	.	.	1900	.	.	.	.	.	.	.	.	.	1910	.	.	.	.	.	.	.	.	.	1920
Sequence	T	L	T	A	S	S	P	L	I	G	V	Y	A	P	T	G	A	T	L	T	A	T	L	T	S	A	N	G	T	P	V	E	G	Q	V	I	N	F	S	V	T	P	E	G	A	T	L	S	G	G	K	V	R	T	N	S	S	G	Q	A
Secondary structure
SS confidence
Disorder						?	?	?	?	?	?	?																															?		?	?	?	?	?	?	?			?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1930	.	.	.	.	.	.	.	.	.	1940	.	.	.	.	.	.	.	.	.	1950	.	.	.	.	.	.	.	.	.	1960	.	.	.	.	.	.	.	.	.	1970	.	.	.	.	.	.	.	.	.	1980
Sequence	P	V	V	L	T	S	N	K	V	G	T	Y	T	V	T	A	S	F	H	N	G	V	T	I	Q	T	Q	T	T	V	K	V	T	G	N	S	S	T	A	H	V	A	S	F	I	A	D	P	S	T	I	A	A	T	N	T	D	L	S	T
Secondary structure
SS confidence
Disorder																				?	?	?	?	?	?	?	?							?	?	?		?	?		?					?	?	?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1990	.	.	.	.	.	.	.	.	.	2000	.	.	.	.	.	.	.	.	.	2010	.	.	.	.	.	.	.	.	.	2020	.	.	.	.	.	.	.	.	.	2030	.	.	.	.	.	.	.	.	.	2040
Sequence	L	K	A	T	V	E	D	G	S	G	N	L	I	E	G	L	T	V	Y	F	A	L	K	S	G	S	A	T	L	T	S	L	T	A	V	T	D	Q	N	G	I	A	T	T	S	V	K	G	A	M	T	G	S	V	T	V	S	A	V	T
Secondary structure
SS confidence
Disorder								?		?														?	?	?	?	?	?			?		?		?												?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	2050	.	.	.	.	.	.	.	.	.	2060	.	.	.	.	.	.	.	.	.	2070	.	.	.	.	.	.	.	.	.	2080	.	.	.	.	.	.	.	.	.	2090	.	.	.	.	.	.	.	.	.	2100
Sequence	T	A	G	G	M	Q	T	V	D	I	T	L	V	A	G	P	A	D	T	S	Q	S	V	L	K	S	N	R	S	S	L	K	G	D	Y	T	D	S	A	E	L	R	L	V	L	H	D	I	S	G	N	P	I	K	V	S	E	G	M	E
Secondary structure
SS confidence
Disorder	?	?	?																?						?	?	?	?	?	?	?	?	?	?	?																			?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	2110	.	.	.	.	.	.	.	.	.	2120	.	.	.	.	.	.	.	.	.	2130	.	.	.	.	.	.	.	.	.	2140	.	.	.	.	.	.	.	.	.	2150	.	.	.	.	.	.	.	.	.	2160
Sequence	F	V	Q	S	G	T	N	V	P	Y	I	K	I	S	A	I	D	Y	S	L	N	I	N	G	D	Y	K	A	T	V	T	G	G	G	E	G	I	A	T	L	I	P	V	L	N	G	V	H	Q	A	G	L	S	T	T	I	Q	F	T	R
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?	?	?		?	?	?	?	?	?																	?	?										?	?	?	?								?
Disorder confidence

	.	.	.	.	.	.	.	.	.	2170	.	.	.	.	.	.	.	.	.	2180	.	.	.	.	.	.	.	.	.	2190	.	.	.	.	.	.	.	.	.	2200	.	.	.	.	.	.	.	.	.	2210	.	.	.	.	.	.	.	.	.	2220
Sequence	A	E	D	K	I	M	S	G	T	V	S	V	N	G	T	D	L	P	T	T	T	F	P	S	Q	G	F	T	G	A	Y	Y	Q	L	N	N	D	N	F	A	P	G	K	T	A	A	D	Y	E	F	S	S	S	A	S	W	V	D	V	D
Secondary structure
SS confidence
Disorder	?	?	?	?	?												?	?	?																			?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	2230	.	.	.	.	.	.	.	.	.	2240	.	.	.	.	.	.	.	.	.	2250	.	.	.	.	.	.	.	.	.	2260	.	.	.	.	.	.	.	.	.	2270	.	.	.	.	.	.	.	.	.	2280
Sequence	A	T	G	K	V	T	F	K	N	V	G	S	N	S	E	R	I	T	A	T	P	K	S	G	G	P	S	Y	V	Y	E	I	R	V	K	S	W	W	V	N	A	G	E	A	F	M	I	Y	S	L	A	E	N	F	C	S	S	N	G	Y
Secondary structure
SS confidence
Disorder									?		?																														?		?	?	?	?	?				?	?		?		?
Disorder confidence

	.	.	.	.	.	.	.	.	.	2290	.	.	.	.	.	.	.	.	.	2300	.	.	.	.	.	.	.	.	.	2310	.	.	.	.	.	.	.	.	.	2320	.	.	.	.	.	.	.	.	.	2330	.	.	.	.	.	.	.	.	.	2340
Sequence	T	L	P	R	A	N	Y	L	N	H	C	S	S	R	G	I	G	S	L	Y	S	E	W	G	D	M	G	H	Y	T	T	D	A	G	F	Q	S	N	M	Y	W	S	S	S	P	A	N	S	S	E	Q	Y	V	V	S	L	A	T	G	D
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?	?	?																										?							?			?	?	?									?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	2350	.	.	.	.	.	.	.	.
Sequence	Q	S	V	F	E	K	L	G	F	A	Y	A	T	C	Y	K	N	L
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?	?									?	?	?
Disorder confidence