Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionQ46803
DateThu Jan 5 12:34:30 GMT 2012
Unique Job ID73202e9a4eaf0a30

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3q98A_
Top template information
PDB header:transferase
Chain: A: PDB Molecule:transcarbamylase;
PDBTitle: structure of ygew encoded protein from e. coli
Confidence and coverage
Confidence:100.0% Coverage: 96%
379 residues ( 96% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MMKTVNELIKDINSLTSHLHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNS
Secondary structure 




















SS confidence 



























































Disorder  ????











??





























?


??





Disorder confidence 



























































 
   .........70.........80.........90.........100.........110.........120
Sequence  GLGISVFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQIAHGETVRETANMISFCADAIG
Secondary structure 






















SS confidence 



























































Disorder 

































????????

















Disorder confidence 



























































 
   .........130.........140.........150.........160.........170.........180
Sequence  IRDDMYLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQCDIDHPTQSMADLAWLREHF
Secondary structure 

























SS confidence 



























































Disorder 







???



















?



























Disorder confidence 



























































 
   .........190.........200.........210.........220.........230.........240
Sequence  GSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVA
Secondary structure 




























SS confidence 



























































Disorder 



























































Disorder confidence 



























































 
   .........250.........260.........270.........280.........290.........300
Sequence  KNNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKVMEERTELLRANDHEGLKALEKQC
Secondary structure 




















SS confidence 



























































Disorder 











































?
??
????

?????
Disorder confidence 



























































 
   .........310.........320.........330.........340.........350.........360
Sequence  LAQNAQHKDWHCTEEMMELTRDGEALYMHCLPADISGVSCKEGEVTEGVFEKYRIATYKE
Secondary structure 

































SS confidence 



























































Disorder  ??

































??





















Disorder confidence 



























































 
   .........370.........380.........390......
Sequence  ASWKPYIIAAMILSRKYAKPGALLEQLLKEAQERVK
Secondary structure 








SS confidence 



































Disorder 


















?????





??????
Disorder confidence 



































 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3q98 chain A

3D model

Region: 3 - 396
Aligned: 379
Modelled: 366
Confidence: 100.0%
Identity: 96%
PDB header:transferase
Chain: A: PDB Molecule:transcarbamylase;
PDBTitle: structure of ygew encoded protein from e. coli

Phyre2

PDB 2otc chain A

3D model

Region: 17 - 378
Aligned: 319
Modelled: 328
Confidence: 100.0%
Identity: 25%
PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: ornithine transcarbamoylase complexed with n-2 (phosphonacetyl)-l-ornithine

Phyre2

PDB 3upd chain A

3D model

Region: 13 - 375
Aligned: 315
Modelled: 330
Confidence: 100.0%
Identity: 25%
PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: 2.9 angstrom crystal structure of ornithine carbamoyltransferase2 (argf) from vibrio vulnificus

Phyre2

PDB 2w37 chain A

3D model

Region: 16 - 378
Aligned: 312
Modelled: 322
Confidence: 100.0%
Identity: 25%
PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase, catabolic;
PDBTitle: crystal structure of the hexameric catabolic ornithine2 transcarbamylase from lactobacillus hilgardii

Phyre2

PDB 1ort chain D

3D model

Region: 18 - 378
Aligned: 317
Modelled: 327
Confidence: 100.0%
Identity: 26%
PDB header:transferase
Chain: D: PDB Molecule:ornithine transcarbamoylase;
PDBTitle: ornithine transcarbamoylase from pseudomonas aeruginosa

Phyre2

PDB 1fvo chain B

3D model

Region: 18 - 381
Aligned: 311
Modelled: 323
Confidence: 100.0%
Identity: 26%
PDB header:transferase
Chain: B: PDB Molecule:ornithine transcarbamylase;
PDBTitle: crystal structure of human ornithine transcarbamylase complexed with2 carbamoyl phosphate

Phyre2

PDB 1a1s chain A

3D model

Region: 18 - 379
Aligned: 310
Modelled: 321
Confidence: 100.0%
Identity: 27%
PDB header:transcarbamylase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: ornithine carbamoyltransferase from pyrococcus furiosus

Phyre2

PDB 1vlv chain A

3D model

Region: 13 - 375
Aligned: 302
Modelled: 310
Confidence: 100.0%
Identity: 30%
PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase (tm1097) from2 thermotoga maritima at 2.25 a resolution

Phyre2

PDB 1ml4 chain A

3D model

Region: 18 - 378
Aligned: 305
Modelled: 327
Confidence: 100.0%
Identity: 21%
PDB header:transferase
Chain: A: PDB Molecule:aspartate transcarbamoylase;
PDBTitle: the pala-liganded aspartate transcarbamoylase catalytic subunit from2 pyrococcus abyssi

Phyre2

PDB 1zq2 chain A

3D model

Region: 22 - 374
Aligned: 316
Modelled: 335
Confidence: 100.0%
Identity: 28%
PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of n-acetyl-l-ornithine transcarbamylase2 complexed with cp

Phyre2

PDB 1tug chain A domain 1

3D model

Region: 17 - 382
Aligned: 305
Modelled: 332
Confidence: 100.0%
Identity: 22%
Fold: ATC-like
Superfamily: Aspartate/ornithine carbamoyltransferase
Family: Aspartate/ornithine carbamoyltransferase

Phyre2

PDB 3sds chain A

3D model

Region: 21 - 380
Aligned: 300
Modelled: 314
Confidence: 100.0%
Identity: 26%
PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase, mitochondrial;
PDBTitle: crystal structure of a mitochondrial ornithine carbamoyltransferase2 from coccidioides immitis

Phyre2

PDB 2p2g chain D

3D model

Region: 22 - 374
Aligned: 288
Modelled: 301
Confidence: 100.0%
Identity: 28%
PDB header:transferase
Chain: D: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase from mycobacterium2 tuberculosis (rv1656): orthorhombic form

Phyre2

PDB 3tpf chain F

3D model

Region: 21 - 379
Aligned: 298
Modelled: 318
Confidence: 100.0%
Identity: 27%
PDB header:transferase
Chain: F: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of anabolic ornithine carbamoyltransferase from2 campylobacter jejuni subsp. jejuni nctc 11168

Phyre2

PDB 1js1 chain Z

3D model

Region: 22 - 380
Aligned: 305
Modelled: 305
Confidence: 100.0%
Identity: 26%
PDB header:transferase
Chain: Z: PDB Molecule:transcarbamylase;
PDBTitle: crystal structure of a new transcarbamylase from the2 anaerobic bacterium bacteroides fragilis at 2.0 a3 resolution

Phyre2

PDB 1pg5 chain A

3D model

Region: 22 - 378
Aligned: 290
Modelled: 323
Confidence: 100.0%
Identity: 18%
PDB header:transferase
Chain: A: PDB Molecule:aspartate carbamoyltransferase;
PDBTitle: crystal structure of the unligated (t-state) aspartate2 transcarbamoylase from the extremely thermophilic archaeon sulfolobus3 acidocaldarius

Phyre2

PDB 2rgw chain D

3D model

Region: 22 - 375
Aligned: 290
Modelled: 319
Confidence: 100.0%
Identity: 24%
PDB header:transferase
Chain: D: PDB Molecule:aspartate carbamoyltransferase;
PDBTitle: catalytic subunit of m. jannaschii aspartate2 transcarbamoylase

Phyre2

PDB 2ef0 chain A

3D model

Region: 21 - 375
Aligned: 283
Modelled: 300
Confidence: 100.0%
Identity: 29%
PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase from thermus2 thermophilus

Phyre2

PDB 3gd5 chain D

3D model

Region: 19 - 377
Aligned: 284
Modelled: 310
Confidence: 100.0%
Identity: 29%
PDB header:transferase
Chain: D: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase from gloeobacter2 violaceus

Phyre2

PDB 3grf chain A

3D model

Region: 20 - 379
Aligned: 293
Modelled: 318
Confidence: 100.0%
Identity: 24%
PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: x-ray structure of ornithine transcarbamoylase from giardia2 lamblia

Phyre2
1

c3q98A_
2

c2otcA_
3

c3updA_
4

c2w37A_
5

c1ortD_
6

c1fvoB_
7

c1a1sA_
8

c1vlvA_
9

c1ml4A_
10

c1zq2A_
11

d1tuga1
12

c3sdsA_
13

c2p2gD_
14

c3tpfF_
15

c1js1Z_
16

c1pg5A_
17

c2rgwD_
18

c2ef0A_
19

c3gd5D_
20

c3grfA_
21



22



23



24



25



26



27



28



29



30



31



32



33



34



35



36



37



38



39



40



41



42



43



44



45



46



47



48



49



50



51



52



53



54



55



56



57



58



59



60



61



62



63



64



65



66



67



68



69



70



71



72



73



74



75



76



77



78



79



80



81



82



83



84



85



86



87



88



89



90



91



92



93



94



95



96



97



98



99



100



101



102



103



104



105



106



107



108



109



110



111



112



113



114



115



116



117



118



119



120



121



122



123



124



125



126



127



128



129



130



131



132



133



134



135



136



137



138



139



140



141



142



143



144



145



146



147



148



149



150



151



152



153



154



155



156



157



158



159



160



161



162



163



164



165



166



167



168



169



170



171



172



173



174



175



176



177



178



179



180



181



182



183



184



185



186



187



188



189



190



191



192



193



194



195



196



197



198



199



200



201



202



203



204



205



206



207



208



209



210



211



212



213



214



215



216



217



218



219



220



221



222



223



224



225



226



227



228



229



230



231



232



233



234



235



236



237



238



239



240



241



242



243



244



245



246



247



248



249



250



251



252



253



254



255



256



257



258



259



260



261



262



263



264



265



266



267



268



269



270



271



272



273



274



275



276



277



278



279



280



281



282



283



284



285



286



287



288



289



290



291



292



293



294



295



296



297



298



299



300



301



302



303



304



305



306



307



308



309



310



311



312



313



314



315



316



317



318



319



320



321



322



323



324



325



326



327



328



329



330



331



332



333



334



335



336



337



338



339



340



341



342



343



344



345



346



347



348



349



350



351



352



353



354



355



356



357



358



359



360



361



362



363



364



365



366



367



368



369



370



371



372



373



374



375



376



377



378



379



380



381



382



383



384



385



386



387



388



389



390



391



392



393



394



395



396



397



398



399



400



401



402



403



404



405



406



407



408



409



410



411



412



413



414



415



416



417



418



419



420



421



422



423



424



425



426



427



428



429



430



431



432



433






Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3q98A_



100.0 96 PDB header:transferase
Chain: A: PDB Molecule:transcarbamylase;
PDBTitle: structure of ygew encoded protein from e. coli
2c2otcA_



100.0 25 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: ornithine transcarbamoylase complexed with n-2 (phosphonacetyl)-l-ornithine
3c3updA_



100.0 25 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: 2.9 angstrom crystal structure of ornithine carbamoyltransferase2 (argf) from vibrio vulnificus
4c2w37A_



100.0 25 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase, catabolic;
PDBTitle: crystal structure of the hexameric catabolic ornithine2 transcarbamylase from lactobacillus hilgardii
5c1ortD_



100.0 26 PDB header:transferase
Chain: D: PDB Molecule:ornithine transcarbamoylase;
PDBTitle: ornithine transcarbamoylase from pseudomonas aeruginosa
6c1fvoB_



100.0 26 PDB header:transferase
Chain: B: PDB Molecule:ornithine transcarbamylase;
PDBTitle: crystal structure of human ornithine transcarbamylase complexed with2 carbamoyl phosphate
7c1a1sA_



100.0 27 PDB header:transcarbamylase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: ornithine carbamoyltransferase from pyrococcus furiosus
8c1vlvA_



100.0 30 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase (tm1097) from2 thermotoga maritima at 2.25 a resolution
9c1ml4A_



100.0 21 PDB header:transferase
Chain: A: PDB Molecule:aspartate transcarbamoylase;
PDBTitle: the pala-liganded aspartate transcarbamoylase catalytic subunit from2 pyrococcus abyssi
10c1zq2A_



100.0 28 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of n-acetyl-l-ornithine transcarbamylase2 complexed with cp
11d1tuga1



100.0 22 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
12c3sdsA_



100.0 26 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase, mitochondrial;
PDBTitle: crystal structure of a mitochondrial ornithine carbamoyltransferase2 from coccidioides immitis
13c2p2gD_



100.0 28 PDB header:transferase
Chain: D: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase from mycobacterium2 tuberculosis (rv1656): orthorhombic form
14c3tpfF_



100.0 27 PDB header:transferase
Chain: F: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of anabolic ornithine carbamoyltransferase from2 campylobacter jejuni subsp. jejuni nctc 11168
15c1js1Z_



100.0 26 PDB header:transferase
Chain: Z: PDB Molecule:transcarbamylase;
PDBTitle: crystal structure of a new transcarbamylase from the2 anaerobic bacterium bacteroides fragilis at 2.0 a3 resolution
16c1pg5A_



100.0 18 PDB header:transferase
Chain: A: PDB Molecule:aspartate carbamoyltransferase;
PDBTitle: crystal structure of the unligated (t-state) aspartate2 transcarbamoylase from the extremely thermophilic archaeon sulfolobus3 acidocaldarius
17c2rgwD_



100.0 24 PDB header:transferase
Chain: D: PDB Molecule:aspartate carbamoyltransferase;
PDBTitle: catalytic subunit of m. jannaschii aspartate2 transcarbamoylase
18c2ef0A_



100.0 29 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase from thermus2 thermophilus
19c3gd5D_



100.0 29 PDB header:transferase
Chain: D: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase from gloeobacter2 violaceus
20c3grfA_



100.0 24 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: x-ray structure of ornithine transcarbamoylase from giardia2 lamblia
21c2at2B_



not modelled 100.0 24 PDB header:
PDB COMPND:
22c3d6nB_



not modelled 100.0 18 PDB header:hydrolase/transferase
Chain: B: PDB Molecule:aspartate carbamoyltransferase;
PDBTitle: crystal structure of aquifex dihydroorotase activated by aspartate2 transcarbamoylase
23c3lxmC_



not modelled 100.0 24 PDB header:transferase
Chain: C: PDB Molecule:aspartate carbamoyltransferase;
PDBTitle: 2.00 angstrom resolution crystal structure of a catalytic2 subunit of an aspartate carbamoyltransferase (pyrb) from3 yersinia pestis co92
24d1ml4a1



not modelled 100.0 25 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
25d1vlva1



not modelled 100.0 26 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
26d1pvva1



not modelled 100.0 28 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
27d1duvg1



not modelled 100.0 30 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
28d1dxha1



not modelled 100.0 27 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
29d1otha1



not modelled 100.0 28 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
30d1ekxa1



not modelled 100.0 31 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
31d1dxha2



not modelled 100.0 24 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
32d2at2a1



not modelled 100.0 27 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
33d1duvg2



not modelled 100.0 21 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
34d1otha2



not modelled 100.0 24 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
35d1pg5a1



not modelled 100.0 22 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
36d1pvva2



not modelled 100.0 28 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
37d1js1x1



not modelled 100.0 23 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
38d1vlva2



not modelled 100.0 34 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
39d1js1x2



not modelled 100.0 30 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
40d1ml4a2



not modelled 100.0 17 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
41d1ekxa2



not modelled 100.0 15 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
42d1pg5a2



not modelled 100.0 14 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
43d2at2a2



not modelled 100.0 21 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
44d2atca2



not modelled 100.0 16 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
45c3gvpB_



not modelled 97.8 21 PDB header:hydrolase
Chain: B: PDB Molecule:adenosylhomocysteinase 3;
PDBTitle: human sahh-like domain of human adenosylhomocysteinase 3
46c3l07B_



not modelled 97.8 16 PDB header:oxidoreductase,hydrolase
Chain: B: PDB Molecule:bifunctional protein fold;
PDBTitle: methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate2 cyclohydrolase, putative bifunctional protein fold from francisella3 tularensis.
47c3d4oA_



not modelled 97.7 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:dipicolinate synthase subunit a;
PDBTitle: crystal structure of dipicolinate synthase subunit a (np_243269.1)2 from bacillus halodurans at 2.10 a resolution
48c4a26B_



not modelled 97.7 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative c-1-tetrahydrofolate synthase, cytoplasmic;
PDBTitle: the crystal structure of leishmania major n5,n10-2 methylenetetrahydrofolate dehydrogenase/cyclohydrolase
49c3d64A_



not modelled 97.7 20 PDB header:hydrolase
Chain: A: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structure of s-adenosyl-l-homocysteine hydrolase from2 burkholderia pseudomallei
50c1b0aA_



not modelled 97.6 18 PDB header:oxidoreductase,hydrolase
Chain: A: PDB Molecule:protein (fold bifunctional protein);
PDBTitle: 5,10, methylene-tetrahydropholate2 dehydrogenase/cyclohydrolase from e coli.
51c1gpjA_



not modelled 97.5 20 PDB header:reductase
Chain: A: PDB Molecule:glutamyl-trna reductase;
PDBTitle: glutamyl-trna reductase from methanopyrus kandleri
52c3oneA_



not modelled 97.5 25 PDB header:hydrolase/hydrolase substrate
Chain: A: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structure of lupinus luteus s-adenosyl-l-homocysteine2 hydrolase in complex with adenine
53c3p2oB_



not modelled 97.5 16 PDB header:oxidoreductase, hydrolase
Chain: B: PDB Molecule:bifunctional protein fold;
PDBTitle: crystal structure of fold bifunctional protein from campylobacter2 jejuni
54c3n58D_



not modelled 97.5 25 PDB header:hydrolase
Chain: D: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structure of s-adenosyl-l-homocysteine hydrolase from brucella2 melitensis in ternary complex with nad and adenosine, orthorhombic3 form
55c1d4fD_



not modelled 97.4 20 PDB header:hydrolase
Chain: D: PDB Molecule:s-adenosylhomocysteine hydrolase;
PDBTitle: crystal structure of recombinant rat-liver d244e mutant s-2 adenosylhomocysteine hydrolase
56c3p2oA_



not modelled 97.3 16 PDB header:oxidoreductase, hydrolase
Chain: A: PDB Molecule:bifunctional protein fold;
PDBTitle: crystal structure of fold bifunctional protein from campylobacter2 jejuni
57c2rirA_



not modelled 97.3 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:dipicolinate synthase, a chain;
PDBTitle: crystal structure of dipicolinate synthase, a chain, from bacillus2 subtilis
58d1a4ia1



not modelled 97.2 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
59c4a5oB_



not modelled 97.0 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:bifunctional protein fold;
PDBTitle: crystal structure of pseudomonas aeruginosa n5, n10-2 methylenetetrahydrofolate dehydrogenase-cyclohydrolase (fold)
60d1gpja2



not modelled 97.0 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
61c3nglA_



not modelled 96.9 12 PDB header:oxidoreductase, hydrolase
Chain: A: PDB Molecule:bifunctional protein fold;
PDBTitle: crystal structure of bifunctional 5,10-methylenetetrahydrofolate2 dehydrogenase / cyclohydrolase from thermoplasma acidophilum
62d1b0aa1



not modelled 96.8 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
63c3n7uD_



not modelled 96.3 17 PDB header:oxidoreductase
Chain: D: PDB Molecule:formate dehydrogenase;
PDBTitle: nad-dependent formate dehydrogenase from higher-plant arabidopsis2 thaliana in complex with nad and azide
64d1pjca1



not modelled 96.3 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
65c2eezG_



not modelled 96.3 20 PDB header:oxidoreductase
Chain: G: PDB Molecule:alanine dehydrogenase;
PDBTitle: crystal structure of alanine dehydrogenase from themus thermophilus
66d2naca1



not modelled 96.3 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
67c1v8bA_



not modelled 96.3 21 PDB header:hydrolase
Chain: A: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structure of a hydrolase
68c1vjtA_



not modelled 96.2 20 PDB header:hydrolase
Chain: A: PDB Molecule:alpha-glucosidase;
PDBTitle: crystal structure of alpha-glucosidase (tm0752) from thermotoga2 maritima at 2.50 a resolution
69d1l7da1



not modelled 96.1 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
70c2nacA_



not modelled 96.1 21 PDB header:oxidoreductase(aldehyde(d),nad+(a))
Chain: A: PDB Molecule:nad-dependent formate dehydrogenase;
PDBTitle: high resolution structures of holo and apo formate dehydrogenase
71c1pjcA_



not modelled 96.1 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:protein (l-alanine dehydrogenase);
PDBTitle: l-alanine dehydrogenase complexed with nad
72c2dbqA_



not modelled 96.1 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:glyoxylate reductase;
PDBTitle: crystal structure of glyoxylate reductase (ph0597) from pyrococcus2 horikoshii ot3, complexed with nadp (i41)
73c2c2xB_



not modelled 96.1 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:methylenetetrahydrofolate dehydrogenase-
PDBTitle: three dimensional structure of bifunctional2 methylenetetrahydrofolate dehydrogenase-cyclohydrolase3 from mycobacterium tuberculosis
74d1mx3a1



not modelled 96.1 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
75c2j6iC_



not modelled 96.0 26 PDB header:oxidoreductase
Chain: C: PDB Molecule:formate dehydrogenase;
PDBTitle: candida boidinii formate dehydrogenase (fdh) c-terminal2 mutant
76c1u8xX_



not modelled 96.0 27 PDB header:hydrolase
Chain: X: PDB Molecule:maltose-6'-phosphate glucosidase;
PDBTitle: crystal structure of glva from bacillus subtilis, a metal-requiring,2 nad-dependent 6-phospho-alpha-glucosidase
77c1l7eC_



not modelled 96.0 16 PDB header:oxidoreductase
Chain: C: PDB Molecule:nicotinamide nucleotide transhydrogenase,
PDBTitle: crystal structure of r. rubrum transhydrogenase domain i2 with bound nadh
78c3p2yA_



not modelled 96.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:alanine dehydrogenase/pyridine nucleotide transhydrogenase;
PDBTitle: crystal structure of alanine dehydrogenase/pyridine nucleotide2 transhydrogenase from mycobacterium smegmatis
79c3dhyC_



not modelled 96.0 29 PDB header:hydrolase
Chain: C: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structures of mycobacterium tuberculosis s-adenosyl-l-2 homocysteine hydrolase in ternary complex with substrate and3 inhibitors
80c1gdhA_



not modelled 95.8 13 PDB header:oxidoreductase(choh (d)-nad(p)+ (a))
Chain: A: PDB Molecule:d-glycerate dehydrogenase;
PDBTitle: crystal structure of a nad-dependent d-glycerate2 dehydrogenase at 2.4 angstroms resolution
81c1a4iB_



not modelled 95.8 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:methylenetetrahydrofolate dehydrogenase /
PDBTitle: human tetrahydrofolate dehydrogenase / cyclohydrolase
82c2omeA_



not modelled 95.8 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:c-terminal-binding protein 2;
PDBTitle: crystal structure of human ctbp2 dehydrogenase complexed with nad(h)
83c3kboB_



not modelled 95.7 10 PDB header:oxidoreductase
Chain: B: PDB Molecule:glyoxylate/hydroxypyruvate reductase a;
PDBTitle: 2.14 angstrom crystal structure of putative oxidoreductase (ycdw) from2 salmonella typhimurium in complex with nadp
84d1li4a1



not modelled 95.6 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
85d1gdha1



not modelled 95.5 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
86c2gcgB_



not modelled 95.5 22 PDB header:oxidoreductase
Chain: B: PDB Molecule:glyoxylate reductase/hydroxypyruvate reductase;
PDBTitle: ternary crystal structure of human glyoxylate2 reductase/hydroxypyruvate reductase
87c1wwkA_



not modelled 95.5 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:phosphoglycerate dehydrogenase;
PDBTitle: crystal structure of phosphoglycerate dehydrogenase from pyrococcus2 horikoshii ot3
88c1obbB_



not modelled 95.4 24 PDB header:hydrolase
Chain: B: PDB Molecule:alpha-glucosidase;
PDBTitle: alpha-glucosidase a, agla, from thermotoga maritima in2 complex with maltose and nad+
89d1pjqa1



not modelled 95.3 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Siroheme synthase N-terminal domain-like
90c2qm3A_



not modelled 95.3 11 PDB header:transferase
Chain: A: PDB Molecule:predicted methyltransferase;
PDBTitle: crystal structure of a predicted methyltransferase from pyrococcus2 furiosus
91c1j4aA_



not modelled 95.3 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-lactate dehydrogenase;
PDBTitle: insights into domain closure, substrate specificity and2 catalysis of d-lactate dehydrogenase from lactobacillus3 bulgaricus
92c3bazA_



not modelled 95.3 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:hydroxyphenylpyruvate reductase;
PDBTitle: structure of hydroxyphenylpyruvate reductase from coleus blumei in2 complex with nadp+
93d1vjta1



not modelled 95.3 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
94c2cukC_



not modelled 95.3 24 PDB header:oxidoreductase
Chain: C: PDB Molecule:glycerate dehydrogenase/glyoxylate reductase;
PDBTitle: crystal structure of tt0316 protein from thermus thermophilus hb8
95c3oj0A_



not modelled 95.3 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:glutamyl-trna reductase;
PDBTitle: crystal structure of glutamyl-trna reductase from thermoplasma2 volcanium (nucleotide binding domain)
96c2eklA_



not modelled 95.2 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-3-phosphoglycerate dehydrogenase;
PDBTitle: structure of st1218 protein from sulfolobus tokodaii
97d1v8ba1



not modelled 95.2 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
98c2g76A_



not modelled 95.1 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-3-phosphoglycerate dehydrogenase;
PDBTitle: crystal structure of human 3-phosphoglycerate dehydrogenase
99d1pzga1



not modelled 95.0 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
100c3gg2B_



not modelled 95.0 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:sugar dehydrogenase, udp-glucose/gdp-mannose
PDBTitle: crystal structure of udp-glucose 6-dehydrogenase from2 porphyromonas gingivalis bound to product udp-glucuronate
101c2bruB_



not modelled 94.9 25 PDB header:oxidoreductase
Chain: B: PDB Molecule:nad(p) transhydrogenase subunit alpha;
PDBTitle: complex of the domain i and domain iii of escherichia coli2 transhydrogenase
102c3evtA_



not modelled 94.9 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:phosphoglycerate dehydrogenase;
PDBTitle: crystal structure of phosphoglycerate dehydrogenase from2 lactobacillus plantarum
103c1ybaC_



not modelled 94.9 21 PDB header:oxidoreductase
Chain: C: PDB Molecule:d-3-phosphoglycerate dehydrogenase;
PDBTitle: the active form of phosphoglycerate dehydrogenase
104d1j4aa1



not modelled 94.8 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
105c1m75B_



not modelled 94.8 21 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-hydroxyacyl-coa dehydrogenase;
PDBTitle: crystal structure of the n208s mutant of l-3-hydroxyacyl-2 coa dehydrogenase in complex with nad and acetoacetyl-coa
106c3oetF_



not modelled 94.8 29 PDB header:oxidoreductase
Chain: F: PDB Molecule:erythronate-4-phosphate dehydrogenase;
PDBTitle: d-erythronate-4-phosphate dehydrogenase complexed with nad
107d2dlda1



not modelled 94.8 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
108c3gg9C_



not modelled 94.7 24 PDB header:oxidoreductase
Chain: C: PDB Molecule:d-3-phosphoglycerate dehydrogenase oxidoreductase protein;
PDBTitle: crystal structure of putative d-3-phosphoglycerate dehydrogenase2 oxidoreductase from ralstonia solanacearum
109c3dfzB_



not modelled 94.7 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:precorrin-2 dehydrogenase;
PDBTitle: sirc, precorrin-2 dehydrogenase
110c3k5pA_



not modelled 94.6 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-3-phosphoglycerate dehydrogenase;
PDBTitle: crystal structure of amino acid-binding act: d-isomer specific 2-2 hydroxyacid dehydrogenase catalytic domain from brucella melitensis
111c1xdwA_



not modelled 94.6 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:nad+-dependent (r)-2-hydroxyglutarate
PDBTitle: nad+-dependent (r)-2-hydroxyglutarate dehydrogenase from2 acidaminococcus fermentans
112c1np3B_



not modelled 94.6 28 PDB header:oxidoreductase
Chain: B: PDB Molecule:ketol-acid reductoisomerase;
PDBTitle: crystal structure of class i acetohydroxy acid isomeroreductase from2 pseudomonas aeruginosa
113d1x7da_



not modelled 94.6 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Ornithine cyclodeaminase-like
114c2pi1C_



not modelled 94.5 22 PDB header:oxidoreductase
Chain: C: PDB Molecule:d-lactate dehydrogenase;
PDBTitle: crystal structure of d-lactate dehydrogenase from aquifex2 aeolicus complexed with nad and lactic acid
115c2hjrK_



not modelled 94.5 16 PDB header:oxidoreductase
Chain: K: PDB Molecule:malate dehydrogenase;
PDBTitle: crystal structure of cryptosporidium parvum malate2 dehydrogenase
116d1np3a2



not modelled 94.4 30 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
117c3c7cB_



not modelled 94.3 24 PDB header:oxidoreductase
Chain: B: PDB Molecule:octopine dehydrogenase;
PDBTitle: a structural basis for substrate and stereo selectivity in2 octopine dehydrogenase (odh-nadh-l-arginine)
118d1qp8a1



not modelled 94.3 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
119d1ygya1



not modelled 94.3 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
120c3k96B_



not modelled 94.1 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:glycerol-3-phosphate dehydrogenase [nad(p)+];
PDBTitle: 2.1 angstrom resolution crystal structure of glycerol-3-phosphate2 dehydrogenase (gpsa) from coxiella burnetii

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0