Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	F	D	S	T	L	N	P	L	W	Q	R	Y	I	L	A	V	Q	E	E	V	K	P	A	L	G	C	T	E	P	I	S	L	A	L	A	A	A	V	A	A	A	E	L	E	G	P	V	E	R	V	E	A	W	V	S	P	N	L	M
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		K	N	G	L	G	V	T	V	P	G	T	G	M	V	G	L	P	I	A	A	A	L	G	A	L	G	G	N	A	N	A	G	L	E	V	L	K	D	A	T	A	Q	A	I	A	D	A	K	A	L	L	A	A	G	K	V	S	V	K	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		Q	E	P	C	D	E	I	L	F	S	R	A	K	V	W	N	G	E	K	W	A	C	V	T	I	V	G	G	H	T	N	I	V	H	I	E	T	H	D	G	V	V	F	T	Q	Q	A	C	V	A	E	G	E	Q	E	S	P	L	T	V
Secondary structure
SS confidence
Disorder																																														?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	S	R	T	T	L	A	E	I	L	K	F	V	N	E	V	P	F	A	A	I	R	F	I	L	D	S	A	K	L	N	C	A	L	S	Q	E	G	L	S	G	K	W	G	L	H	I	G	A	T	L	E	K	Q	C	E	R	G	L	L
Secondary structure
SS confidence
Disorder																																						?		?	?	?	?	?	?	?								?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	K	D	L	S	S	S	I	V	I	R	T	S	A	A	S	D	A	R	M	G	G	A	T	L	P	A	M	S	N	S	G	S	G	N	Q	G	I	T	A	T	M	P	V	V	V	V	A	E	H	F	G	A	D	D	E	R	L	A	R
Secondary structure
SS confidence
Disorder																															?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		A	L	M	L	S	H	L	S	A	I	Y	I	H	N	Q	L	P	R	L	S	A	L	C	A	A	T	T	A	A	M	G	A	A	A	G	M	A	W	L	V	D	G	R	Y	E	T	I	S	M	A	I	S	S	M	I	G	D	V	S	G
Secondary structure
SS confidence
Disorder															?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		M	I	C	D	G	A	S	N	S	C	A	M	K	V	S	T	S	A	S	A	A	W	K	A	V	L	M	A	L	D	D	T	A	V	T	G	N	E	G	I	V	A	H	D	V	E	Q	S	I	A	N	L	C	A	L	A	S	H	S	M
Secondary structure
SS confidence
Disorder																															?			?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.
Sequence		Q	Q	T	D	R	Q	I	I	E	I	M	A	S	K	A	R
Secondary structure
SS confidence
Disorder													?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2hp0 chain A Region: 194 - 397 Aligned: 198 Modelled: 204 Confidence: 98.5% Identity: 14% PDB header:isomerase Chain: A: PDB Molecule:ids-epimerase; PDBTitle: crystal structure of iminodisuccinate epimerase Phyre2 PDB 1szq chain A Region: 186 - 392 Aligned: 207 Modelled: 207 Confidence: 98.0% Identity: 14% Fold: 2-methylcitrate dehydratase PrpD Superfamily: 2-methylcitrate dehydratase PrpD Family: 2-methylcitrate dehydratase PrpD Phyre2 PDB 3u4g chain A Region: 329 - 361 Aligned: 33 Modelled: 30 Confidence: 56.6% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:namn:dmb phosphoribosyltransferase; PDBTitle: the structure of cobt from pyrococcus horikoshii Phyre2 PDB 3nep chain X Region: 7 - 115 Aligned: 108 Modelled: 109 Confidence: 53.0% Identity: 18% PDB header:oxidoreductase Chain: X: PDB Molecule:malate dehydrogenase; PDBTitle: 1.55a resolution structure of malate dehydrogenase from salinibacter2 ruber Phyre2 PDB 1v59 chain A domain 2 Region: 45 - 163 Aligned: 114 Modelled: 119 Confidence: 47.3% Identity: 12% Fold: FAD/NAD(P)-binding domain Superfamily: FAD/NAD(P)-binding domain Family: FAD/NAD-linked reductases, N-terminal and central domains Phyre2 PDB 2o2j chain A Region: 245 - 293 Aligned: 44 Modelled: 49 Confidence: 38.7% Identity: 27% PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase beta chain; PDBTitle: mycobacterium tuberculosis tryptophan synthase beta chain2 dimer (apoform) Phyre2 PDB 2klz chain A Region: 294 - 307 Aligned: 14 Modelled: 14 Confidence: 28.3% Identity: 57% PDB header:hydrolase Chain: A: PDB Molecule:ataxin-3; PDBTitle: solution structure of the tandem uim domain of ataxin-3 complexed with2 ubiquitin Phyre2 PDB 1x1q chain A Region: 247 - 282 Aligned: 35 Modelled: 36 Confidence: 23.0% Identity: 23% PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase beta chain; PDBTitle: crystal structure of tryptophan synthase beta chain from thermus2 thermophilus hb8 Phyre2 PDB 1o58 chain A Region: 247 - 294 Aligned: 44 Modelled: 48 Confidence: 20.3% Identity: 23% Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes Phyre2 PDB 3l0z chain C Region: 329 - 353 Aligned: 25 Modelled: 25 Confidence: 19.5% Identity: 20% PDB header:transferase Chain: C: PDB Molecule:putative nicotinate-nucleotide-dimethylbenzimidazole PDBTitle: crystal structure of a putative nicotinate-nucleotide-2 dimethylbenzimidazole phosphoribosyltransferase from3 methanocaldococcus jannaschii dsm 2661 Phyre2 PDB 2hsg chain A domain 1 Region: 258 - 302 Aligned: 45 Modelled: 45 Confidence: 18.8% Identity: 24% Fold: lambda repressor-like DNA-binding domains Superfamily: lambda repressor-like DNA-binding domains Family: GalR/LacI-like bacterial regulator Phyre2 PDB 1m75 chain B Region: 62 - 113 Aligned: 46 Modelled: 52 Confidence: 18.5% Identity: 39% PDB header:oxidoreductase Chain: B: PDB Molecule:3-hydroxyacyl-coa dehydrogenase; PDBTitle: crystal structure of the n208s mutant of l-3-hydroxyacyl-2 coa dehydrogenase in complex with nad and acetoacetyl-coa Phyre2 PDB 1efa chain A domain 1 Region: 258 - 302 Aligned: 45 Modelled: 45 Confidence: 16.7% Identity: 18% Fold: lambda repressor-like DNA-binding domains Superfamily: lambda repressor-like DNA-binding domains Family: GalR/LacI-like bacterial regulator Phyre2 PDB 1e3j chain A domain 2 Region: 27 - 89 Aligned: 46 Modelled: 46 Confidence: 15.6% Identity: 35% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Alcohol dehydrogenase-like, C-terminal domain Phyre2 PDB 3e49 chain A Region: 1 - 113 Aligned: 113 Modelled: 113 Confidence: 15.0% Identity: 19% PDB header:metal binding protein Chain: A: PDB Molecule:uncharacterized protein duf849 with a tim barrel fold; PDBTitle: crystal structure of a prokaryotic domain of unknown function (duf849)2 with a tim barrel fold (bxe_c0966) from burkholderia xenovorans lb4003 at 1.75 a resolution Phyre2 PDB 1v71 chain A domain 1 Region: 247 - 294 Aligned: 43 Modelled: 48 Confidence: 14.8% Identity: 19% Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes Phyre2 PDB 2hld chain H Region: 53 - 76 Aligned: 24 Modelled: 24 Confidence: 14.3% Identity: 25% PDB header:hydrolase Chain: H: PDB Molecule:atp synthase delta chain, mitochondrial; PDBTitle: crystal structure of yeast mitochondrial f1-atpase Phyre2 PDB 1wfz chain A Region: 324 - 386 Aligned: 61 Modelled: 63 Confidence: 13.7% Identity: 13% Fold: SufE/NifU Superfamily: SufE/NifU Family: NifU/IscU domain Phyre2 PDB 1r4q chain A Region: 10 - 30 Aligned: 21 Modelled: 21 Confidence: 12.2% Identity: 5% Fold: Ribosome inactivating proteins (RIP) Superfamily: Ribosome inactivating proteins (RIP) Family: Shiga toxin, A-chain Phyre2 PDB 1fcj chain A Region: 247 - 294 Aligned: 44 Modelled: 48 Confidence: 12.2% Identity: 27% Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes Phyre2 1 c2hp0A_ 2 d1szqa_ 3 c3u4gA_ 4 c3nepX_ 5 d1v59a2 6 c2o2jA_ 7 c2klzA_ 8 c1x1qA_ 9 d1o58a_ 10 c3l0zC_ 11 d2hsga1 12 c1m75B_ 13 d1efaa1 14 d1e3ja2 15 c3e49A_ 16 d1v71a1 17 c2hldH_ 18 d1wfza_ 19 d1r4qa_ 20 d1fcja_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2hp0A_ 98.5 14 PDB header:isomerase Chain: A: PDB Molecule:ids-epimerase; PDBTitle: crystal structure of iminodisuccinate epimerase 2 d1szqa_ 98.0 14 Fold:2-methylcitrate dehydratase PrpD Superfamily:2-methylcitrate dehydratase PrpD Family:2-methylcitrate dehydratase PrpD 3 c3u4gA_ 56.6 18 PDB header:transferase Chain: A: PDB Molecule:namn:dmb phosphoribosyltransferase; PDBTitle: the structure of cobt from pyrococcus horikoshii 4 c3nepX_ 53.0 18 PDB header:oxidoreductase Chain: X: PDB Molecule:malate dehydrogenase; PDBTitle: 1.55a resolution structure of malate dehydrogenase from salinibacter2 ruber 5 d1v59a2 47.3 12 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 6 c2o2jA_ 38.7 27 PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase beta chain; PDBTitle: mycobacterium tuberculosis tryptophan synthase beta chain2 dimer (apoform) 7 c2klzA_ 28.3 57 PDB header:hydrolase Chain: A: PDB Molecule:ataxin-3; PDBTitle: solution structure of the tandem uim domain of ataxin-3 complexed with2 ubiquitin 8 c1x1qA_ 23.0 23 PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase beta chain; PDBTitle: crystal structure of tryptophan synthase beta chain from thermus2 thermophilus hb8 9 d1o58a_ 20.3 23 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 10 c3l0zC_ 19.5 20 PDB header:transferase Chain: C: PDB Molecule:putative nicotinate-nucleotide-dimethylbenzimidazole PDBTitle: crystal structure of a putative nicotinate-nucleotide-2 dimethylbenzimidazole phosphoribosyltransferase from3 methanocaldococcus jannaschii dsm 2661 11 d2hsga1 18.8 24 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:GalR/LacI-like bacterial regulator 12 c1m75B_ 18.5 39 PDB header:oxidoreductase Chain: B: PDB Molecule:3-hydroxyacyl-coa dehydrogenase; PDBTitle: crystal structure of the n208s mutant of l-3-hydroxyacyl-2 coa dehydrogenase in complex with nad and acetoacetyl-coa 13 d1efaa1 16.7 18 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:GalR/LacI-like bacterial regulator 14 d1e3ja2 15.6 35 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 15 c3e49A_ 15.0 19 PDB header:metal binding protein Chain: A: PDB Molecule:uncharacterized protein duf849 with a tim barrel fold; PDBTitle: crystal structure of a prokaryotic domain of unknown function (duf849)2 with a tim barrel fold (bxe_c0966) from burkholderia xenovorans lb4003 at 1.75 a resolution 16 d1v71a1 14.8 19 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 17 c2hldH_ 14.3 25 PDB header:hydrolase Chain: H: PDB Molecule:atp synthase delta chain, mitochondrial; PDBTitle: crystal structure of yeast mitochondrial f1-atpase 18 d1wfza_ 13.7 13 Fold:SufE/NifU Superfamily:SufE/NifU Family:NifU/IscU domain 19 d1r4qa_ 12.2 5 Fold:Ribosome inactivating proteins (RIP) Superfamily:Ribosome inactivating proteins (RIP) Family:Shiga toxin, A-chain 20 d1fcja_ 12.2 27 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 21 d1nvmb1 not modelled 12.1 24 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 22 c3doaA_ not modelled 11.6 17 PDB header:protein binding Chain: A: PDB Molecule:fibrinogen binding protein; PDBTitle: the crystal structure of the fibrinogen binding protein from2 staphylococcus aureus 23 c3rfuC_ not modelled 11.2 13 PDB header:hydrolase, membrane protein Chain: C: PDB Molecule:copper efflux atpase; PDBTitle: crystal structure of a copper-transporting pib-type atpase 24 c3co7C_ not modelled 10.9 29 PDB header:transcription/dna Chain: C: PDB Molecule:forkhead box protein o1; PDBTitle: crystal structure of foxo1 dbd bound to dbe2 dna 25 d1j0aa_ not modelled 10.7 18 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 26 c3a58A_ not modelled 10.6 20 PDB header:protein transport/exocytosis Chain: A: PDB Molecule:exocyst complex component sec3; PDBTitle: crystal structure of sec3p - rho1p complex from2 saccharomyces cerevisiae 27 d3bpya1 not modelled 10.6 36 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Forkhead DNA-binding domain 28 c3g73A_ not modelled 10.6 29 PDB header:transcription/dna Chain: A: PDB Molecule:forkhead box protein m1; PDBTitle: structure of the foxm1 dna binding 29 d1kq8a_ not modelled 10.5 43 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Forkhead DNA-binding domain 30 c1kq8A_ not modelled 10.5 43 PDB header:transcription Chain: A: PDB Molecule:hepatocyte nuclear factor 3 forkhead homolog 1; PDBTitle: solution structure of winged helix protein hfh-1 31 d2dx7a1 not modelled 10.5 23 Fold:ATC-like Superfamily:Aspartate/glutamate racemase Family:Aspartate/glutamate racemase 32 d1tyza_ not modelled 10.5 11 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 33 c3c1zA_ not modelled 10.4 17 PDB header:dna binding protein Chain: A: PDB Molecule:dna integrity scanning protein disa; PDBTitle: structure of the ligand-free form of a bacterial dna damage2 sensor protein 34 d1ve1a1 not modelled 10.2 26 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 35 d2ldxa1 not modelled 10.2 27 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:LDH N-terminal domain-like 36 d2bjca1 not modelled 10.2 18 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:GalR/LacI-like bacterial regulator 37 d1j6ua3 not modelled 10.0 20 Fold:Ribokinase-like Superfamily:MurD-like peptide ligases, catalytic domain Family:MurCDEF 38 d2a07f1 not modelled 10.0 29 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Forkhead DNA-binding domain 39 d2hfha_ not modelled 9.8 29 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Forkhead DNA-binding domain 40 c1e17A_ not modelled 9.7 36 PDB header:dna binding domain Chain: A: PDB Molecule:afx; PDBTitle: solution structure of the dna binding domain of the human2 forkhead transcription factor afx (foxo4) 41 d1ijwc_ not modelled 9.5 18 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:Recombinase DNA-binding domain 42 d1kn1b_ not modelled 9.4 23 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins 43 d1pgja2 not modelled 9.2 24 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 44 c3imoC_ not modelled 9.1 33 PDB header:unknown function Chain: C: PDB Molecule:integron cassette protein; PDBTitle: structure from the mobile metagenome of vibrio cholerae.2 integron cassette protein vch_cass14 45 d2vnud2 not modelled 8.9 44 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 46 d1wkva1 not modelled 8.8 11 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 47 c2okvC_ not modelled 8.7 9 PDB header:hydrolase Chain: C: PDB Molecule:probable d-tyrosyl-trna(tyr) deacylase 1; PDBTitle: c-myc dna unwinding element binding protein 48 d1dxla2 not modelled 8.7 15 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 49 d1k1xa3 not modelled 8.7 15 Fold:7-stranded beta/alpha barrel Superfamily:Glycoside hydrolase/deacetylase Family:4-alpha-glucanotransferase, N-terminal domain 50 c3mogA_ not modelled 8.6 39 PDB header:oxidoreductase Chain: A: PDB Molecule:probable 3-hydroxybutyryl-coa dehydrogenase; PDBTitle: crystal structure of 3-hydroxybutyryl-coa dehydrogenase from2 escherichia coli k12 substr. mg1655 51 c3sqgF_ not modelled 8.6 26 PDB header:transferase Chain: F: PDB Molecule:methyl-coenzyme m reductase, gamma subunit; PDBTitle: crystal structure of a methyl-coenzyme m reductase purified from black2 sea mats 52 d2bhsa1 not modelled 8.4 28 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 53 d1hcra_ not modelled 8.3 18 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:Recombinase DNA-binding domain 54 d1b74a2 not modelled 8.3 19 Fold:ATC-like Superfamily:Aspartate/glutamate racemase Family:Aspartate/glutamate racemase 55 d2f1ka2 not modelled 8.2 23 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 56 c3dt5A_ not modelled 8.1 25 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein af_0924; PDBTitle: c_terminal domain of protein of unknown function af_0924 from2 archaeoglobus fulgidus. 57 d1j7ga_ not modelled 8.1 19 Fold:DTD-like Superfamily:DTD-like Family:DTD-like 58 d1f2da_ not modelled 7.9 14 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 59 d2gv8a2 not modelled 7.9 21 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 60 d1qpza1 not modelled 7.7 14 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:GalR/LacI-like bacterial regulator 61 c2yqfA_ not modelled 7.7 35 PDB header:protein binding Chain: A: PDB Molecule:ankyrin-1; PDBTitle: solution structure of the death domain of ankyrin-1 62 c3kg4A_ not modelled 7.7 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an uncharacterized protein from mannheimia2 succiniciproducens 63 d1gv4a2 not modelled 7.5 19 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 64 c2pqmA_ not modelled 7.4 27 PDB header:lyase Chain: A: PDB Molecule:cysteine synthase; PDBTitle: crystal structure of cysteine synthase (oass) from entamoeba2 histolytica at 1.86 a resolution 65 c1nvmB_ not modelled 7.4 24 PDB header:lyase/oxidoreductase Chain: B: PDB Molecule:acetaldehyde dehydrogenase (acylating); PDBTitle: crystal structure of a bifunctional aldolase-dehydrogenase :2 sequestering a reactive and volatile intermediate 66 d1iioa_ not modelled 7.3 28 Fold:EF Hand-like Superfamily:Hypothetical protein MTH865 Family:Hypothetical protein MTH865 67 d2c6ya1 not modelled 7.2 21 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Forkhead DNA-binding domain 68 c2zskA_ not modelled 7.1 100 PDB header:unknown function Chain: A: PDB Molecule:226aa long hypothetical aspartate racemase; PDBTitle: crystal structure of ph1733, an aspartate racemase2 homologue, from pyrococcus horikoshii ot3 69 c1i7mD_ not modelled 7.1 15 PDB header:lyase Chain: D: PDB Molecule:s-adenosylmethionine decarboxylase beta chain; PDBTitle: human s-adenosylmethionine decarboxylase with covalently bound2 pyruvoyl group and complexed with 4-amidinoindan-1-one-2'-3 amidinohydrazone 70 c3j08A_ not modelled 7.0 13 PDB header:hydrolase, metal transport Chain: A: PDB Molecule:copper-exporting p-type atpase a; PDBTitle: high resolution helical reconstruction of the bacterial p-type atpase2 copper transporter copa 71 c2vmlA_ not modelled 7.0 20 PDB header:photosynthesis Chain: A: PDB Molecule:phycocyanin alpha chain; PDBTitle: the monoclinic structure of phycocyanin from gloeobacter2 violaceus 72 d1dlja2 not modelled 6.9 25 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 73 d1jsca3 not modelled 6.9 17 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 74 c1dliA_ not modelled 6.9 25 PDB header:oxidoreductase Chain: A: PDB Molecule:udp-glucose dehydrogenase; PDBTitle: the first structure of udp-glucose dehydrogenase (udpgdh) reveals the2 catalytic residues necessary for the two-fold oxidation 75 d1d5va_ not modelled 6.9 29 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Forkhead DNA-binding domain 76 c2jfzB_ not modelled 6.8 80 PDB header:isomerase Chain: B: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of helicobacter pylori glutamate racemase2 in complex with d-glutamate and an inhibitor 77 c1p8cD_ not modelled 6.7 28 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:conserved hypothetical protein; PDBTitle: crystal structure of tm1620 (apc4843) from thermotoga2 maritima 78 c3d3kD_ not modelled 6.6 14 PDB header:protein binding Chain: D: PDB Molecule:enhancer of mrna-decapping protein 3; PDBTitle: crystal structure of human edc3p 79 d7mdha1 not modelled 6.4 26 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:LDH N-terminal domain-like 80 c2pwzG_ not modelled 6.4 22 PDB header:oxidoreductase Chain: G: PDB Molecule:malate dehydrogenase; PDBTitle: crystal structure of the apo form of e.coli malate dehydrogenase 81 c2q2kA_ not modelled 6.4 24 PDB header:dna binding protein/dna Chain: A: PDB Molecule:hypothetical protein; PDBTitle: structure of nucleic-acid binding protein 82 d1dd3a1 not modelled 6.3 12 Fold:Ribosomal protein L7/12, oligomerisation (N-terminal) domain Superfamily:Ribosomal protein L7/12, oligomerisation (N-terminal) domain Family:Ribosomal protein L7/12, oligomerisation (N-terminal) domain 83 c2kdtA_ not modelled 6.2 21 PDB header:protein transport Chain: A: PDB Molecule:neuroendocrine convertase 1; PDBTitle: pc1/3 dcsg sorting domain structure in dpc 84 d1allb_ not modelled 6.2 19 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins 85 c1o7dA_ not modelled 6.1 12 PDB header:hydrolase Chain: A: PDB Molecule:lysosomal alpha-mannosidase; PDBTitle: the structure of the bovine lysosomal a-mannosidase2 suggests a novel mechanism for low ph activation 86 c3m9hB_ not modelled 6.1 44 PDB header:chaperone Chain: B: PDB Molecule:proteasome-associated atpase; PDBTitle: crystal structure of the amino terminal coiled coil domain of the2 mycobacterium tuberculosis proteasomal atpase mpa 87 d1poia_ not modelled 6.0 22 Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:CoA transferase alpha subunit-like 88 d2nmla1 not modelled 6.0 8 Fold:ERH-like Superfamily:ERH-like Family:ERH-like 89 d3bvua3 not modelled 6.0 12 Fold:7-stranded beta/alpha barrel Superfamily:Glycoside hydrolase/deacetylase Family:alpha-mannosidase 90 d1v8za1 not modelled 6.0 21 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 91 d1neka1 not modelled 6.0 9 Fold:Spectrin repeat-like Superfamily:Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain Family:Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 92 c3jvfC_ not modelled 6.0 44 PDB header:signaling protein / cytokine Chain: C: PDB Molecule:interleukin-17 receptor a; PDBTitle: crystal structure of an interleukin-17 receptor complex 93 c2jnhA_ not modelled 5.9 33 PDB header:ligase Chain: A: PDB Molecule:e3 ubiquitin-protein ligase cbl-b; PDBTitle: solution structure of the uba domain from cbl-b 94 c1p5jA_ not modelled 5.9 21 PDB header:lyase Chain: A: PDB Molecule:l-serine dehydratase; PDBTitle: crystal structure analysis of human serine dehydratase 95 d1p5ja_ not modelled 5.9 21 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 96 d1ez4a1 not modelled 5.9 25 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:LDH N-terminal domain-like 97 c2jfnA_ not modelled 5.9 80 PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of escherichia coli glutamate racemase2 in complex with l-glutamate and activator udp-murnac-ala 98 c1b74A_ not modelled 5.8 80 PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: glutamate racemase from aquifex pyrophilus 99 c3a3jA_ not modelled 5.8 16 PDB header:hydrolase Chain: A: PDB Molecule:pbp5; PDBTitle: crystal structures of penicillin binding protein 5 from2 haemophilus influenzae

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0