Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	I	V	I	A	P	D	S	F	K	E	S	L	S	A	E	K	C	C	Q	A	I	K	A	G	F	S	T	L	F	P	D	A	N	Y	I	C	L	P	I	A	D	G	G	E	G	T	V	D	A	M	V	A	A	T	G	G	N	I
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	T	L	E	V	C	G	P	M	G	E	K	V	N	A	F	Y	G	L	T	G	D	G	K	T	A	V	I	E	M	A	A	A	S	G	L	M	L	V	A	P	E	K	R	N	P	L	L	A	S	S	F	G	T	G	E	L	I	R	H
Secondary structure
SS confidence
Disorder																																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	L	D	N	D	I	R	H	I	I	L	G	I	G	G	S	A	T	V	D	G	G	M	G	M	A	Q	A	L	G	V	R	F	L	D	A	D	G	Q	A	L	A	A	N	G	G	N	L	A	R	V	A	S	I	E	M	D	E	C	D
Secondary structure
SS confidence
Disorder																																												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		P	R	L	A	N	C	H	I	E	V	A	C	D	V	D	N	P	L	V	G	A	R	G	A	A	A	V	F	G	P	Q	K	G	A	T	P	E	M	V	E	E	L	E	Q	G	L	Q	N	Y	A	R	V	L	Q	Q	Q	T	E	I	N
Secondary structure
SS confidence
Disorder																												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		V	C	Q	M	A	G	G	G	A	A	G	G	M	G	I	A	A	A	V	F	L	N	A	D	I	K	P	G	I	E	I	V	L	N	A	V	N	L	A	Q	A	V	Q	G	A	A	L	V	I	T	G	E	G	R	I	D	S	Q	T	A
Secondary structure
SS confidence
Disorder				?	?	?	?	?		?																																																?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		G	G	K	A	P	L	G	V	A	S	V	A	K	Q	F	N	V	P	V	I	G	I	A	G	V	L	G	D	G	V	E	V	V	H	Q	Y	G	I	D	A	V	F	S	I	L	P	R	L	A	P	L	A	E	V	L	A	S	G	E	T
Secondary structure
SS confidence
Disorder		?		?																																											?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.
Sequence		N	L	F	N	S	A	R	N	I	A	C	A	I	K	I	G	Q	G	I	K	N
Secondary structure
SS confidence
Disorder																	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3cwc chain B Region: 1 - 379 Aligned: 372 Modelled: 378 Confidence: 100.0% Identity: 56% PDB header:transferase Chain: B: PDB Molecule:putative glycerate kinase 2; PDBTitle: crystal structure of putative glycerate kinase 2 from salmonella2 typhimurium lt2 Phyre2 PDB 1to6 chain A Region: 1 - 377 Aligned: 370 Modelled: 373 Confidence: 100.0% Identity: 39% Fold: Glycerate kinase I Superfamily: Glycerate kinase I Family: Glycerate kinase I Phyre2 PDB 1e0t chain A domain 2 Region: 127 - 321 Aligned: 165 Modelled: 180 Confidence: 95.1% Identity: 13% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: Pyruvate kinase Phyre2 PDB 1liu chain A domain 2 Region: 127 - 321 Aligned: 170 Modelled: 180 Confidence: 94.4% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: Pyruvate kinase Phyre2 PDB 1pkl chain A domain 2 Region: 127 - 321 Aligned: 166 Modelled: 195 Confidence: 93.0% Identity: 19% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: Pyruvate kinase Phyre2 PDB 1a3x chain A domain 2 Region: 127 - 321 Aligned: 165 Modelled: 180 Confidence: 89.8% Identity: 14% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: Pyruvate kinase Phyre2 PDB 1vb5 chain A Region: 281 - 329 Aligned: 49 Modelled: 49 Confidence: 88.7% Identity: 16% Fold: NagB/RpiA/CoA transferase-like Superfamily: NagB/RpiA/CoA transferase-like Family: IF2B-like Phyre2 PDB 1psw chain A Region: 274 - 365 Aligned: 79 Modelled: 79 Confidence: 87.3% Identity: 15% Fold: UDP-Glycosyltransferase/glycogen phosphorylase Superfamily: UDP-Glycosyltransferase/glycogen phosphorylase Family: ADP-heptose LPS heptosyltransferase II Phyre2 PDB 2g50 chain A domain 2 Region: 127 - 321 Aligned: 170 Modelled: 180 Confidence: 87.0% Identity: 17% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: Pyruvate kinase Phyre2 PDB 1w2w chain J Region: 278 - 325 Aligned: 45 Modelled: 48 Confidence: 84.6% Identity: 22% PDB header:isomerase Chain: J: PDB Molecule:5-methylthioribose-1-phosphate isomerase; PDBTitle: crystal structure of yeast ypr118w, a methylthioribose-1-2 phosphate isomerase related to regulatory eif2b subunits Phyre2 PDB 3ecs chain D Region: 281 - 325 Aligned: 45 Modelled: 43 Confidence: 84.2% Identity: 24% PDB header:translation Chain: D: PDB Molecule:translation initiation factor eif-2b subunit PDBTitle: crystal structure of human eif2b alpha Phyre2 PDB 1ydg chain A Region: 1 - 43 Aligned: 39 Modelled: 43 Confidence: 83.9% Identity: 15% Fold: Flavodoxin-like Superfamily: Flavoproteins Family: WrbA-like Phyre2 PDB 1w5f chain A Region: 278 - 380 Aligned: 100 Modelled: 103 Confidence: 83.5% Identity: 20% PDB header:cell division Chain: A: PDB Molecule:cell division protein ftsz; PDBTitle: ftsz, t7 mutated, domain swapped (t. maritima) Phyre2 PDB 1t5o chain A Region: 283 - 331 Aligned: 49 Modelled: 49 Confidence: 82.7% Identity: 29% Fold: NagB/RpiA/CoA transferase-like Superfamily: NagB/RpiA/CoA transferase-like Family: IF2B-like Phyre2 PDB 2vap chain A domain 1 Region: 278 - 374 Aligned: 94 Modelled: 97 Confidence: 82.6% Identity: 22% Fold: Tubulin nucleotide-binding domain-like Superfamily: Tubulin nucleotide-binding domain-like Family: Tubulin, GTPase domain Phyre2 PDB 1rq2 chain A domain 1 Region: 278 - 375 Aligned: 95 Modelled: 97 Confidence: 82.1% Identity: 24% Fold: Tubulin nucleotide-binding domain-like Superfamily: Tubulin nucleotide-binding domain-like Family: Tubulin, GTPase domain Phyre2 PDB 3a11 chain D Region: 282 - 325 Aligned: 44 Modelled: 44 Confidence: 81.6% Identity: 18% PDB header:isomerase Chain: D: PDB Molecule:translation initiation factor eif-2b, delta PDBTitle: crystal structure of ribose-1,5-bisphosphate isomerase from2 thermococcus kodakaraensis kod1 Phyre2 PDB 1a3w chain B Region: 215 - 321 Aligned: 77 Modelled: 77 Confidence: 80.5% Identity: 16% PDB header:transferase Chain: B: PDB Molecule:pyruvate kinase; PDBTitle: pyruvate kinase from saccharomyces cerevisiae complexed with fbp, pg,2 mn2+ and k+ Phyre2 PDB 1w59 chain B Region: 278 - 380 Aligned: 100 Modelled: 103 Confidence: 78.7% Identity: 21% PDB header:cell division Chain: B: PDB Molecule:cell division protein ftsz homolog 1; PDBTitle: ftsz dimer, empty (m. jannaschii) Phyre2 PDB 2yvk chain A Region: 283 - 325 Aligned: 40 Modelled: 43 Confidence: 75.8% Identity: 30% PDB header:isomerase Chain: A: PDB Molecule:methylthioribose-1-phosphate isomerase; PDBTitle: crystal structure of 5-methylthioribose 1-phosphate2 isomerase product complex from bacillus subtilis Phyre2 1 c3cwcB_ 2 d1to6a_ 3 d1e0ta2 4 d1liua2 5 d1pkla2 6 d1a3xa2 7 d1vb5a_ 8 d1pswa_ 9 d2g50a2 10 c1w2wJ_ 11 c3ecsD_ 12 d1ydga_ 13 c1w5fA_ 14 d1t5oa_ 15 d2vapa1 16 d1rq2a1 17 c3a11D_ 18 c1a3wB_ 19 c1w59B_ 20 c2yvkA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3cwcB_ 100.0 56 PDB header:transferase Chain: B: PDB Molecule:putative glycerate kinase 2; PDBTitle: crystal structure of putative glycerate kinase 2 from salmonella2 typhimurium lt2 2 d1to6a_ 100.0 39 Fold:Glycerate kinase I Superfamily:Glycerate kinase I Family:Glycerate kinase I 3 d1e0ta2 95.1 13 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 4 d1liua2 94.4 15 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 5 d1pkla2 93.0 19 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 6 d1a3xa2 89.8 14 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 7 d1vb5a_ 88.7 16 Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:IF2B-like 8 d1pswa_ 87.3 15 Fold:UDP-Glycosyltransferase/glycogen phosphorylase Superfamily:UDP-Glycosyltransferase/glycogen phosphorylase Family:ADP-heptose LPS heptosyltransferase II 9 d2g50a2 87.0 17 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 10 c1w2wJ_ 84.6 22 PDB header:isomerase Chain: J: PDB Molecule:5-methylthioribose-1-phosphate isomerase; PDBTitle: crystal structure of yeast ypr118w, a methylthioribose-1-2 phosphate isomerase related to regulatory eif2b subunits 11 c3ecsD_ 84.2 24 PDB header:translation Chain: D: PDB Molecule:translation initiation factor eif-2b subunit PDBTitle: crystal structure of human eif2b alpha 12 d1ydga_ 83.9 15 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:WrbA-like 13 c1w5fA_ 83.5 20 PDB header:cell division Chain: A: PDB Molecule:cell division protein ftsz; PDBTitle: ftsz, t7 mutated, domain swapped (t. maritima) 14 d1t5oa_ 82.7 29 Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:IF2B-like 15 d2vapa1 82.6 22 Fold:Tubulin nucleotide-binding domain-like Superfamily:Tubulin nucleotide-binding domain-like Family:Tubulin, GTPase domain 16 d1rq2a1 82.1 24 Fold:Tubulin nucleotide-binding domain-like Superfamily:Tubulin nucleotide-binding domain-like Family:Tubulin, GTPase domain 17 c3a11D_ 81.6 18 PDB header:isomerase Chain: D: PDB Molecule:translation initiation factor eif-2b, delta PDBTitle: crystal structure of ribose-1,5-bisphosphate isomerase from2 thermococcus kodakaraensis kod1 18 c1a3wB_ 80.5 16 PDB header:transferase Chain: B: PDB Molecule:pyruvate kinase; PDBTitle: pyruvate kinase from saccharomyces cerevisiae complexed with fbp, pg,2 mn2+ and k+ 19 c1w59B_ 78.7 21 PDB header:cell division Chain: B: PDB Molecule:cell division protein ftsz homolog 1; PDBTitle: ftsz dimer, empty (m. jannaschii) 20 c2yvkA_ 75.8 30 PDB header:isomerase Chain: A: PDB Molecule:methylthioribose-1-phosphate isomerase; PDBTitle: crystal structure of 5-methylthioribose 1-phosphate2 isomerase product complex from bacillus subtilis 21 d1t9ka_ not modelled 75.7 30 Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:IF2B-like 22 c2h1fB_ not modelled 74.2 20 PDB header:transferase Chain: B: PDB Molecule:lipopolysaccharide heptosyltransferase-1; PDBTitle: e. coli heptosyltransferase waac with adp 23 d2a0ua1 not modelled 73.9 21 Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:IF2B-like 24 c1aqfB_ not modelled 73.4 17 PDB header:transferase Chain: B: PDB Molecule:pyruvate kinase; PDBTitle: pyruvate kinase from rabbit muscle with mg, k, and l-2 phospholactate 25 c1t5aB_ not modelled 71.7 17 PDB header:transferase Chain: B: PDB Molecule:pyruvate kinase, m2 isozyme; PDBTitle: human pyruvate kinase m2 26 c2vgbB_ not modelled 71.6 13 PDB header:transferase Chain: B: PDB Molecule:pyruvate kinase isozymes r/l; PDBTitle: human erythrocyte pyruvate kinase 27 d1xi3a_ not modelled 71.1 18 Fold:TIM beta/alpha-barrel Superfamily:Thiamin phosphate synthase Family:Thiamin phosphate synthase 28 d1izca_ not modelled 69.2 20 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:HpcH/HpaI aldolase 29 c1izcA_ not modelled 69.2 20 PDB header:lyase Chain: A: PDB Molecule:macrophomate synthase intermolecular diels-alderase; PDBTitle: crystal structure analysis of macrophomate synthase 30 c3eoeC_ not modelled 69.1 23 PDB header:transferase Chain: C: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure of pyruvate kinase from toxoplasma gondii, 55.m00007 31 c2q1yB_ not modelled 68.5 22 PDB header:cell cycle, signaling protein Chain: B: PDB Molecule:cell division protein ftsz; PDBTitle: crystal structure of cell division protein ftsz from mycobacterium2 tuberculosis in complex with gtp-gamma-s 32 c3e0vB_ not modelled 68.4 17 PDB header:transferase Chain: B: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure of pyruvate kinase from leishmania mexicana in2 complex with sulphate ions 33 c2rhoB_ not modelled 67.1 22 PDB header:cell cycle Chain: B: PDB Molecule:cell division protein ftsz; PDBTitle: synthetic gene encoded bacillus subtilis ftsz ncs dimer with2 bound gdp and gtp-gamma-s 34 c1pklB_ not modelled 65.6 17 PDB header:transferase Chain: B: PDB Molecule:protein (pyruvate kinase); PDBTitle: the structure of leishmania pyruvate kinase 35 c3t07D_ not modelled 65.5 18 PDB header:transferase/transferase inhibitor Chain: D: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure of s. aureus pyruvate kinase in complex with a2 naturally occurring bis-indole alkaloid 36 d1wv2a_ not modelled 65.4 17 Fold:TIM beta/alpha-barrel Superfamily:ThiG-like Family:ThiG-like 37 d1ofua1 not modelled 65.2 24 Fold:Tubulin nucleotide-binding domain-like Superfamily:Tubulin nucleotide-binding domain-like Family:Tubulin, GTPase domain 38 c1e0tD_ not modelled 64.6 13 PDB header:phosphotransferase Chain: D: PDB Molecule:pyruvate kinase; PDBTitle: r292d mutant of e. coli pyruvate kinase 39 c2ppvA_ not modelled 64.4 16 PDB header:transferase Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a protein belonging to the upf0052 (se_0549) from2 staphylococcus epidermidis atcc 12228 at 2.00 a resolution 40 c3tovB_ not modelled 63.4 27 PDB header:transferase Chain: B: PDB Molecule:glycosyl transferase family 9; PDBTitle: the crystal structure of the glycosyl transferase family 9 from2 veillonella parvula dsm 2008 41 c2p0yA_ not modelled 63.0 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein lp_0780; PDBTitle: crystal structure of q88yi3_lacpl from lactobacillus2 plantarum. northeast structural genomics consortium target3 lpr6 42 c2f9iD_ not modelled 62.7 14 PDB header:transferase Chain: D: PDB Molecule:acetyl-coenzyme a carboxylase carboxyl PDBTitle: crystal structure of the carboxyltransferase subunit of acc2 from staphylococcus aureus 43 c1ofuB_ not modelled 62.7 24 PDB header:bacterial cell division inhibitor Chain: B: PDB Molecule:cell division protein ftsz; PDBTitle: crystal structure of sula:ftsz from pseudomonas aeruginosa 44 d2f9yb1 not modelled 61.3 15 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Biotin dependent carboxylase carboxyltransferase domain 45 c2f9yB_ not modelled 61.3 15 PDB header:ligase Chain: B: PDB Molecule:acetyl-coenzyme a carboxylase carboxyl transferase subunit PDBTitle: the crystal structure of the carboxyltransferase subunit of acc from2 escherichia coli 46 d1ecfa1 not modelled 59.7 12 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 47 c2hjgA_ not modelled 59.1 17 PDB header:hydrolase Chain: A: PDB Molecule:gtp-binding protein enga; PDBTitle: the crystal structure of the b. subtilis yphc gtpase in2 complex with gdp 48 c2vxyA_ not modelled 58.4 25 PDB header:cell cycle Chain: A: PDB Molecule:cell division protein ftsz; PDBTitle: the structure of ftsz from bacillus subtilis at 1.7a2 resolution 49 c3hbmA_ not modelled 56.7 18 PDB header:hydrolase Chain: A: PDB Molecule:udp-sugar hydrolase; PDBTitle: crystal structure of pseg from campylobacter jejuni 50 c2e28A_ not modelled 56.2 18 PDB header:transferase Chain: A: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure analysis of pyruvate kinase from bacillus2 stearothermophilus 51 d2hzba1 not modelled 55.4 18 Fold:CofD-like Superfamily:CofD-like Family:CofD-like 52 d1vima_ not modelled 55.3 13 Fold:SIS domain Superfamily:SIS domain Family:mono-SIS domain 53 c3ma8A_ not modelled 55.0 15 PDB header:transferase Chain: A: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure of cgd1_2040, a pyruvate kinase from cryptosporidium2 parvum 54 d2naca2 not modelled 53.1 12 Fold:Flavodoxin-like Superfamily:Formate/glycerate dehydrogenase catalytic domain-like Family:Formate/glycerate dehydrogenases, substrate-binding domain 55 c2ze3A_ not modelled 53.0 14 PDB header:isomerase Chain: A: PDB Molecule:dfa0005; PDBTitle: crystal structure of dfa0005 complexed with alpha-ketoglutarate: a2 novel member of the icl/pepm superfamily from alkali-tolerant3 deinococcus ficus 56 c2v82A_ not modelled 52.9 13 PDB header:lyase Chain: A: PDB Molecule:2-dehydro-3-deoxy-6-phosphogalactonate aldolase; PDBTitle: kdpgal complexed to kdpgal 57 d1pjqa1 not modelled 52.1 15 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Siroheme synthase N-terminal domain-like 58 c2vawA_ not modelled 51.4 23 PDB header:cell cycle Chain: A: PDB Molecule:cell division protein ftsz; PDBTitle: ftsz pseudomonas aeruginosa gdp 59 c1pixB_ not modelled 51.1 22 PDB header:lyase Chain: B: PDB Molecule:glutaconyl-coa decarboxylase a subunit; PDBTitle: crystal structure of the carboxyltransferase subunit of the2 bacterial ion pump glutaconyl-coenzyme a decarboxylase 60 d1f8ya_ not modelled 50.8 5 Fold:Flavodoxin-like Superfamily:N-(deoxy)ribosyltransferase-like Family:N-deoxyribosyltransferase 61 d1q7ra_ not modelled 50.0 15 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT) 62 c2bf9A_ not modelled 49.9 26 PDB header:hormone Chain: A: PDB Molecule:pancreatic hormone; PDBTitle: anisotropic refinement of avian (turkey) pancreatic2 polypeptide at 0.99 angstroms resolution. 63 c3trjC_ not modelled 49.9 13 PDB header:isomerase Chain: C: PDB Molecule:phosphoheptose isomerase; PDBTitle: structure of a phosphoheptose isomerase from francisella tularensis 64 d1diha1 not modelled 49.6 16 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 65 d1vrga1 not modelled 49.6 31 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Biotin dependent carboxylase carboxyltransferase domain 66 d1w5fa1 not modelled 49.6 19 Fold:Tubulin nucleotide-binding domain-like Superfamily:Tubulin nucleotide-binding domain-like Family:Tubulin, GTPase domain 67 d1j0aa_ not modelled 49.2 14 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 68 c4a1dG_ not modelled 49.0 15 PDB header:ribosome Chain: G: PDB Molecule:rpl30; PDBTitle: t.thermophila 60s ribosomal subunit in complex with initiation2 factor 6. this file contains 26s rrna and proteins of3 molecule 4. 69 c3na3A_ not modelled 48.8 25 PDB header:protein binding Chain: A: PDB Molecule:dna mismatch repair protein mlh1; PDBTitle: mutl protein homolog 1 isoform 1 from homo sapiens 70 c3ct7E_ not modelled 48.1 12 PDB header:isomerase Chain: E: PDB Molecule:d-allulose-6-phosphate 3-epimerase; PDBTitle: crystal structure of d-allulose 6-phosphate 3-epimerase2 from escherichia coli k-12 71 d1pixa2 not modelled 47.5 20 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Biotin dependent carboxylase carboxyltransferase domain 72 d1t0kb_ not modelled 47.2 13 Fold:Bacillus chorismate mutase-like Superfamily:L30e-like Family:L30e/L7ae ribosomal proteins 73 c1ronA_ not modelled 47.2 22 PDB header:neuropeptide Chain: A: PDB Molecule:neuropeptide y; PDBTitle: nmr solution structure of human neuropeptide y 74 c1tz5A_ not modelled 46.8 30 PDB header:hormone/growth factor Chain: A: PDB Molecule:chimera of pancreatic hormone and neuropeptide y; PDBTitle: [pnpy19-23]-hpp bound to dpc micelles 75 d1p3da1 not modelled 45.3 15 Fold:MurCD N-terminal domain Superfamily:MurCD N-terminal domain Family:MurCD N-terminal domain 76 d1w41a1 not modelled 44.8 21 Fold:Bacillus chorismate mutase-like Superfamily:L30e-like Family:L30e/L7ae ribosomal proteins 77 c3pqeD_ not modelled 44.4 19 PDB header:oxidoreductase Chain: D: PDB Molecule:l-lactate dehydrogenase; PDBTitle: crystal structure of l-lactate dehydrogenase from bacillus subtilis2 with h171c mutation 78 d1on3a1 not modelled 44.0 24 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Biotin dependent carboxylase carboxyltransferase domain 79 c3khdC_ not modelled 43.9 17 PDB header:transferase Chain: C: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure of pff1300w. 80 c1drwA_ not modelled 43.8 18 PDB header:oxidoreductase Chain: A: PDB Molecule:dihydrodipicolinate reductase; PDBTitle: escherichia coli dhpr/nhdh complex 81 d1j6ua1 not modelled 43.7 9 Fold:MurCD N-terminal domain Superfamily:MurCD N-terminal domain Family:MurCD N-terminal domain 82 d1dxea_ not modelled 42.7 13 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:HpcH/HpaI aldolase 83 c1xnwD_ not modelled 42.3 27 PDB header:ligase Chain: D: PDB Molecule:propionyl-coa carboxylase complex b subunit; PDBTitle: acyl-coa carboxylase beta subunit from s. coelicolor (pccb),2 apo form #2, mutant d422i 84 c3o63B_ not modelled 42.3 22 PDB header:transferase Chain: B: PDB Molecule:probable thiamine-phosphate pyrophosphorylase; PDBTitle: crystal structure of thiamin phosphate synthase from mycobacterium2 tuberculosis 85 c1x0uB_ not modelled 42.2 29 PDB header:lyase Chain: B: PDB Molecule:hypothetical methylmalonyl-coa decarboxylase alpha subunit; PDBTitle: crystal structure of the carboxyl transferase subunit of putative pcc2 of sulfolobus tokodaii 86 c3glmD_ not modelled 41.4 23 PDB header:lyase Chain: D: PDB Molecule:glutaconyl-coa decarboxylase subunit a; PDBTitle: glutaconyl-coa decarboxylase a subunit from clostridium2 symbiosum co-crystallized with crotonyl-coa 87 c2dezA_ not modelled 41.3 26 PDB header:neuropeptide Chain: A: PDB Molecule:peptide yy; PDBTitle: structure of human pyy 88 c3bzrA_ not modelled 41.3 15 PDB header:membrane protein, protein transport Chain: A: PDB Molecule:escu; PDBTitle: crystal structure of escu c-terminal domain with n262d mutation, space2 group p 41 21 2 89 d3bzra1 not modelled 41.3 15 Fold:EscU C-terminal domain-like Superfamily:EscU C-terminal domain-like Family:EscU C-terminal domain-like 90 d1ycga1 not modelled 40.3 32 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 91 d1k9vf_ not modelled 40.2 13 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT) 92 c3qz6A_ not modelled 40.0 18 PDB header:lyase Chain: A: PDB Molecule:hpch/hpai aldolase; PDBTitle: the crystal structure of hpch/hpai aldolase from desulfitobacterium2 hafniense dcb-2 93 d2csua2 not modelled 40.0 24 Fold:Flavodoxin-like Superfamily:Succinyl-CoA synthetase domains Family:Succinyl-CoA synthetase domains 94 c3n6rF_ not modelled 39.9 29 PDB header:ligase Chain: F: PDB Molecule:propionyl-coa carboxylase, beta subunit; PDBTitle: crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc) 95 c1zosE_ not modelled 39.3 19 PDB header:hydrolase Chain: E: PDB Molecule:5'-methylthioadenosine / s-adenosylhomocysteine PDBTitle: structure of 5'-methylthionadenosine/s-adenosylhomocysteine2 nucleosidase from s. pneumoniae with a transition-state3 inhibitor mt-imma 96 c2yybA_ not modelled 38.7 29 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein ttha1606; PDBTitle: crystal structure of ttha1606 from thermus thermophilus hb8 97 c2r6r1_ not modelled 38.5 20 PDB header:cell cycle Chain: 1: PDB Molecule:cell division protein ftsz; PDBTitle: aquifex aeolicus ftsz 98 d2a7sa1 not modelled 38.2 31 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Biotin dependent carboxylase carboxyltransferase domain 99 c1on3E_ not modelled 38.0 24 PDB header:transferase Chain: E: PDB Molecule:methylmalonyl-coa carboxyltransferase 12s PDBTitle: transcarboxylase 12s crystal structure: hexamer assembly2 and substrate binding to a multienzyme core (with3 methylmalonyl-coenzyme a and methylmalonic acid bound) 100 d1xnya1 not modelled 37.7 27 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Biotin dependent carboxylase carboxyltransferase domain 101 d1nmpa_ not modelled 37.6 24 Fold:NIF3 (NGG1p interacting factor 3)-like Superfamily:NIF3 (NGG1p interacting factor 3)-like Family:NIF3 (NGG1p interacting factor 3)-like 102 c1vrgE_ not modelled 37.6 35 PDB header:ligase Chain: E: PDB Molecule:propionyl-coa carboxylase, beta subunit; PDBTitle: crystal structure of propionyl-coa carboxylase, beta subunit (tm0716)2 from thermotoga maritima at 2.30 a resolution 103 c3t7yB_ not modelled 37.5 18 PDB header:protein transport Chain: B: PDB Molecule:yop proteins translocation protein u; PDBTitle: structure of an autocleavage-inactive mutant of the cytoplasmic domain2 of ct091, the yscu homologue of chlamydia trachomatis 104 d2nv0a1 not modelled 37.5 9 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT) 105 d1jvna2 not modelled 37.2 17 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT) 106 c2yxbA_ not modelled 36.9 14 PDB header:isomerase Chain: A: PDB Molecule:coenzyme b12-dependent mutase; PDBTitle: crystal structure of the methylmalonyl-coa mutase alpha-subunit from2 aeropyrum pernix 107 c2zkiH_ not modelled 36.9 16 PDB header:transcription Chain: H: PDB Molecule:199aa long hypothetical trp repressor binding PDBTitle: crystal structure of hypothetical trp repressor binding2 protein from sul folobus tokodaii (st0872) 108 c2q7xA_ not modelled 36.8 7 PDB header:transferase Chain: A: PDB Molecule:upf0052 protein sp_1565; PDBTitle: crystal structure of a putative phospho transferase (sp_1565) from2 streptococcus pneumoniae tigr4 at 2.00 a resolution 109 c3hgmD_ not modelled 36.7 18 PDB header:signaling protein Chain: D: PDB Molecule:universal stress protein tead; PDBTitle: universal stress protein tead from the trap transporter2 teaabc of halomonas elongata 110 c3ceuA_ not modelled 36.3 17 PDB header:transferase Chain: A: PDB Molecule:thiamine phosphate pyrophosphorylase; PDBTitle: crystal structure of thiamine phosphate pyrophosphorylase2 (bt_0647) from bacteroides thetaiotaomicron. northeast3 structural genomics consortium target btr268 111 c3oirA_ not modelled 36.1 10 PDB header:transport protein Chain: A: PDB Molecule:sulfate transporter sulfate transporter family protein; PDBTitle: crystal structure of sulfate transporter family protein from wolinella2 succinogenes 112 d2ffea1 not modelled 35.4 12 Fold:CofD-like Superfamily:CofD-like Family:CofD-like 113 c2zklA_ not modelled 35.3 13 PDB header:isomerase Chain: A: PDB Molecule:capsular polysaccharide synthesis enzyme cap5f; PDBTitle: crystal structure of capsular polysaccharide assembling protein capf2 from staphylococcus aureus 114 c2bg5C_ not modelled 35.1 17 PDB header:transferase Chain: C: PDB Molecule:phosphoenolpyruvate-protein kinase; PDBTitle: crystal structure of the phosphoenolpyruvate-binding enzyme2 i-domain from the thermoanaerobacter tengcongensis pep:3 sugar phosphotransferase system (pts) 115 c3h4lB_ not modelled 35.0 22 PDB header:dna binding protein, protein binding Chain: B: PDB Molecule:dna mismatch repair protein pms1; PDBTitle: crystal structure of n terminal domain of a dna repair protein 116 d2bo1a1 not modelled 34.7 17 Fold:Bacillus chorismate mutase-like Superfamily:L30e-like Family:L30e/L7ae ribosomal proteins 117 d1vhca_ not modelled 34.2 7 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 118 c2hwgA_ not modelled 33.8 17 PDB header:transferase Chain: A: PDB Molecule:phosphoenolpyruvate-protein phosphotransferase; PDBTitle: structure of phosphorylated enzyme i of the2 phosphoenolpyruvate:sugar phosphotransferase system 119 c2v5jB_ not modelled 33.4 7 PDB header:lyase Chain: B: PDB Molecule:2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; PDBTitle: apo class ii aldolase hpch 120 c3f6sI_ not modelled 33.4 21 PDB header:electron transport Chain: I: PDB Molecule:flavodoxin; PDBTitle: desulfovibrio desulfuricans (atcc 29577) oxidized flavodoxin2 alternate conformers

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0