Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP07023
DateThu Jan 5 11:00:05 GMT 2012
Unique Job ID5b66f9dce904bb02

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2pv7B_
Top template information
PDB header:isomerase, oxidoreductase
Chain: B: PDB Molecule:t-protein [includes: chorismate mutase (ec 5.4.99.5) (cm)
PDBTitle: crystal structure of chorismate mutase / prephenate dehydrogenase2 (tyra) (1574749) from haemophilus influenzae rd at 2.00 a resolution
Confidence and coverage
Confidence:100.0% Coverage: 75%
279 residues ( 75% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
361 residues ( 97%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MVAELTALRDQIDEVDKALLNLLAKRLELVAEVGEVKSRFGLPIYVPEREASMLASRRAE
Secondary structure 







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Disorder  ???







































???













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   .........70.........80.........90.........100.........110.........120
Sequence  AEALGVPPDLIEDVLRRVMRESYSSENDKGFKTLCPSLRPVVIVGGGGQMGRLFEKMLTL
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Disorder 
??????


















?????????????




















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   .........130.........140.........150.........160.........170.........180
Sequence  SGYQVRILEQHDWDRAADIVADAGMVIVSVPIHVTEQVIGKLPPLPKDCILVDLASVKNG
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   .........190.........200.........210.........220.........230.........240
Sequence  PLQAMLVAHDGPVLGLHPMFGPDSGSLAKQVVVWCDGRKPEAYQWFLEQIQVWGARLHRI
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?



































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   .........250.........260.........270.........280.........290.........300
Sequence  SAVEHDQNMAFIQALRHFATFAYGLHLAEENVQLEQLLALSSPIYRLELAMVGRLFAQDP
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?
???


























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   .........310.........320.........330.........340.........350.........360
Sequence  QLYADIIMSSERNLALIKRYYKRFGEAIELLEQGDKQAFIDSFRKVEHWFGDYAQRFQSE
Secondary structure 



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?
?
























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   .........370...
Sequence  SRVLLRQANDNRQ
Secondary structure 

SS confidence 












Disorder 






??????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2pv7 chain B

3D model

Region: 90 - 368
Aligned: 279
Modelled: 278
Confidence: 100.0%
Identity: 56%
PDB header:isomerase, oxidoreductase
Chain: B: PDB Molecule:t-protein [includes: chorismate mutase (ec 5.4.99.5) (cm)
PDBTitle: crystal structure of chorismate mutase / prephenate dehydrogenase2 (tyra) (1574749) from haemophilus influenzae rd at 2.00 a resolution

Phyre2

PDB 3ktd chain C

3D model

Region: 99 - 356
Aligned: 249
Modelled: 258
Confidence: 100.0%
Identity: 21%
PDB header:oxidoreductase
Chain: C: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of a putative prephenate dehydrogenase (cgl0226)2 from corynebacterium glutamicum atcc 13032 at 2.60 a resolution

Phyre2

PDB 2g5c chain D

3D model

Region: 98 - 350
Aligned: 248
Modelled: 252
Confidence: 100.0%
Identity: 22%
PDB header:oxidoreductase
Chain: D: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from aquifex aeolicus

Phyre2

PDB 3ggp chain A

3D model

Region: 99 - 352
Aligned: 249
Modelled: 254
Confidence: 100.0%
Identity: 22%
PDB header:oxidoreductase
Chain: A: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from a. aeolicus in2 complex with hydroxyphenyl propionate and nad+

Phyre2

PDB 2f1k chain D

3D model

Region: 100 - 355
Aligned: 250
Modelled: 256
Confidence: 100.0%
Identity: 20%
PDB header:oxidoreductase
Chain: D: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of synechocystis arogenate dehydrogenase

Phyre2

PDB 3b1f chain A

3D model

Region: 97 - 352
Aligned: 251
Modelled: 256
Confidence: 100.0%
Identity: 21%
PDB header:oxidoreductase
Chain: A: PDB Molecule:putative prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from streptococcus2 mutans

Phyre2

PDB 3dzb chain A

3D model

Region: 99 - 356
Aligned: 253
Modelled: 258
Confidence: 100.0%
Identity: 19%
PDB header:biosynthetic protein
Chain: A: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from streptococcus2 thermophilus

Phyre2

PDB 2pv7 chain A domain 2

3D model

Region: 91 - 240
Aligned: 150
Modelled: 150
Confidence: 100.0%
Identity: 53%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain

Phyre2

PDB 2pv7 chain A domain 1

3D model

Region: 241 - 368
Aligned: 124
Modelled: 128
Confidence: 100.0%
Identity: 59%
Fold: 6-phosphogluconate dehydrogenase C-terminal domain-like
Superfamily: 6-phosphogluconate dehydrogenase C-terminal domain-like
Family: TyrA dimerization domain-like

Phyre2

PDB 2f1k chain A domain 1

3D model

Region: 241 - 355
Aligned: 111
Modelled: 115
Confidence: 99.9%
Identity: 20%
Fold: 6-phosphogluconate dehydrogenase C-terminal domain-like
Superfamily: 6-phosphogluconate dehydrogenase C-terminal domain-like
Family: TyrA dimerization domain-like

Phyre2

PDB 2g5c chain A domain 1

3D model

Region: 241 - 352
Aligned: 105
Modelled: 110
Confidence: 99.9%
Identity: 18%
Fold: 6-phosphogluconate dehydrogenase C-terminal domain-like
Superfamily: 6-phosphogluconate dehydrogenase C-terminal domain-like
Family: TyrA dimerization domain-like

Phyre2

PDB 3tri chain B

3D model

Region: 97 - 348
Aligned: 242
Modelled: 252
Confidence: 99.9%
Identity: 16%
PDB header:oxidoreductase
Chain: B: PDB Molecule:pyrroline-5-carboxylate reductase;
PDBTitle: structure of a pyrroline-5-carboxylate reductase (proc) from coxiella2 burnetii

Phyre2

PDB 3rmi chain A

3D model

Region: 2 - 88
Aligned: 87
Modelled: 87
Confidence: 99.8%
Identity: 30%
PDB header:isomerase
Chain: A: PDB Molecule:chorismate mutase protein;
PDBTitle: crystal structure of chorismate mutase from bartonella henselae str.2 houston-1 in complex with malate

Phyre2

PDB 3d1l chain B

3D model

Region: 99 - 326
Aligned: 226
Modelled: 228
Confidence: 99.8%
Identity: 13%
PDB header:oxidoreductase
Chain: B: PDB Molecule:putative nadp oxidoreductase bf3122;
PDBTitle: crystal structure of putative nadp oxidoreductase bf3122 from2 bacteroides fragilis

Phyre2

PDB 2ahr chain B

3D model

Region: 99 - 348
Aligned: 237
Modelled: 247
Confidence: 99.8%
Identity: 16%
PDB header:oxidoreductase
Chain: B: PDB Molecule:putative pyrroline carboxylate reductase;
PDBTitle: crystal structures of 1-pyrroline-5-carboxylate reductase from human2 pathogen streptococcus pyogenes

Phyre2

PDB 2gtv chain X domain 1

3D model

Region: 1 - 84
Aligned: 84
Modelled: 84
Confidence: 99.8%
Identity: 30%
Fold: Chorismate mutase II
Superfamily: Chorismate mutase II
Family: monomeric chorismate mutase

Phyre2

PDB 2ag8 chain A

3D model

Region: 99 - 353
Aligned: 238
Modelled: 254
Confidence: 99.8%
Identity: 13%
PDB header:oxidoreductase
Chain: A: PDB Molecule:pyrroline-5-carboxylate reductase;
PDBTitle: nadp complex of pyrroline-5-carboxylate reductase from neisseria2 meningitidis

Phyre2

PDB 2g5c chain A domain 2

3D model

Region: 98 - 239
Aligned: 141
Modelled: 141
Confidence: 99.8%
Identity: 25%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain

Phyre2

PDB 2gra chain A

3D model

Region: 100 - 357
Aligned: 241
Modelled: 258
Confidence: 99.8%
Identity: 14%
PDB header:oxidoreductase
Chain: A: PDB Molecule:pyrroline-5-carboxylate reductase 1;
PDBTitle: crystal structure of human pyrroline-5-carboxylate reductase complexed2 with nadp

Phyre2

PDB 1ecm chain A

3D model

Region: 3 - 92
Aligned: 90
Modelled: 90
Confidence: 99.8%
Identity: 28%
Fold: Chorismate mutase II
Superfamily: Chorismate mutase II
Family: Dimeric chorismate mutase

Phyre2

PDB 2d8d chain A domain 1

3D model

Region: 3 - 82
Aligned: 79
Modelled: 79
Confidence: 99.7%
Identity: 35%
Fold: Chorismate mutase II
Superfamily: Chorismate mutase II
Family: Dimeric chorismate mutase

Phyre2
1

c2pv7B_
2

c3ktdC_
3

c2g5cD_
4

c3ggpA_
5

c2f1kD_
6

c3b1fA_
7

c3dzbA_
8

d2pv7a2
9

d2pv7a1
10

d2f1ka1
11

d2g5ca1
12

c3triB_
13

c3rmiA_
14

c3d1lB_
15

c2ahrB_
16

d2gtvx1
17

c2ag8A_
18

d2g5ca2
19

c2graA_
20

d1ecma_
21



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d2d8da1
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2pv7B_



100.0 56 PDB header:isomerase, oxidoreductase
Chain: B: PDB Molecule:t-protein [includes: chorismate mutase (ec 5.4.99.5) (cm)
PDBTitle: crystal structure of chorismate mutase / prephenate dehydrogenase2 (tyra) (1574749) from haemophilus influenzae rd at 2.00 a resolution
2c3ktdC_



100.0 21 PDB header:oxidoreductase
Chain: C: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of a putative prephenate dehydrogenase (cgl0226)2 from corynebacterium glutamicum atcc 13032 at 2.60 a resolution
3c2g5cD_



100.0 22 PDB header:oxidoreductase
Chain: D: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from aquifex aeolicus
4c3ggpA_



100.0 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from a. aeolicus in2 complex with hydroxyphenyl propionate and nad+
5c2f1kD_



100.0 20 PDB header:oxidoreductase
Chain: D: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of synechocystis arogenate dehydrogenase
6c3b1fA_



100.0 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from streptococcus2 mutans
7c3dzbA_



100.0 19 PDB header:biosynthetic protein
Chain: A: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from streptococcus2 thermophilus
8d2pv7a2



100.0 53 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
9d2pv7a1



100.0 59 Fold:6-phosphogluconate dehydrogenase C-terminal domain-like
Superfamily:6-phosphogluconate dehydrogenase C-terminal domain-like
Family:TyrA dimerization domain-like
10d2f1ka1



99.9 20 Fold:6-phosphogluconate dehydrogenase C-terminal domain-like
Superfamily:6-phosphogluconate dehydrogenase C-terminal domain-like
Family:TyrA dimerization domain-like
11d2g5ca1



99.9 18 Fold:6-phosphogluconate dehydrogenase C-terminal domain-like
Superfamily:6-phosphogluconate dehydrogenase C-terminal domain-like
Family:TyrA dimerization domain-like
12c3triB_



99.9 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:pyrroline-5-carboxylate reductase;
PDBTitle: structure of a pyrroline-5-carboxylate reductase (proc) from coxiella2 burnetii
13c3rmiA_



99.8 30 PDB header:isomerase
Chain: A: PDB Molecule:chorismate mutase protein;
PDBTitle: crystal structure of chorismate mutase from bartonella henselae str.2 houston-1 in complex with malate
14c3d1lB_



99.8 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative nadp oxidoreductase bf3122;
PDBTitle: crystal structure of putative nadp oxidoreductase bf3122 from2 bacteroides fragilis
15c2ahrB_



99.8 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative pyrroline carboxylate reductase;
PDBTitle: crystal structures of 1-pyrroline-5-carboxylate reductase from human2 pathogen streptococcus pyogenes
16d2gtvx1



99.8 30 Fold:Chorismate mutase II
Superfamily:Chorismate mutase II
Family:monomeric chorismate mutase
17c2ag8A_



99.8 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:pyrroline-5-carboxylate reductase;
PDBTitle: nadp complex of pyrroline-5-carboxylate reductase from neisseria2 meningitidis
18d2g5ca2



99.8 25 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
19c2graA_



99.8 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:pyrroline-5-carboxylate reductase 1;
PDBTitle: crystal structure of human pyrroline-5-carboxylate reductase complexed2 with nadp
20d1ecma_



99.8 28 Fold:Chorismate mutase II
Superfamily:Chorismate mutase II
Family:Dimeric chorismate mutase
21c2izzE_



not modelled 99.8 15 PDB header:oxidoreductase
Chain: E: PDB Molecule:pyrroline-5-carboxylate reductase 1;
PDBTitle: crystal structure of human pyrroline-5-carboxylate2 reductase
22c3c24A_



not modelled 99.8 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of a putative oxidoreductase (yp_511008.1) from2 jannaschia sp. ccs1 at 1.62 a resolution
23c2rcyB_



not modelled 99.7 12 PDB header:oxidoreductase
Chain: B: PDB Molecule:pyrroline carboxylate reductase;
PDBTitle: crystal structure of plasmodium falciparum pyrroline carboxylate2 reductase (mal13p1.284) with nadp bound
24d2f1ka2



not modelled 99.7 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
25d2d8da1



99.7 35 Fold:Chorismate mutase II
Superfamily:Chorismate mutase II
Family:Dimeric chorismate mutase
26c2ep9A_



not modelled 99.7 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:l-gulonate 3-dehydrogenase;
PDBTitle: crystal structure of the rabbit l-gulonate 3-dehydrogenase2 (nadh form)
27c1i36A_



not modelled 99.6 14 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:conserved hypothetical protein mth1747;
PDBTitle: structure of conserved protein mth1747 of unknown function2 reveals structural similarity with 3-hydroxyacid3 dehydrogenases
28c3gt0A_



not modelled 99.6 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:pyrroline-5-carboxylate reductase;
PDBTitle: crystal structure of pyrroline 5-carboxylate reductase from bacillus2 cereus. northeast structural genomics consortium target bcr38b
29d2h9da1



not modelled 99.6 23 Fold:Chorismate mutase II
Superfamily:Chorismate mutase II
Family:Dimeric chorismate mutase
30c3cumA_



not modelled 99.6 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable 3-hydroxyisobutyrate dehydrogenase;
PDBTitle: crystal structure of a possible 3-hydroxyisobutyrate dehydrogenase2 from pseudomonas aeruginosa pao1
31c2uyyD_



not modelled 99.6 17 PDB header:cytokine
Chain: D: PDB Molecule:n-pac protein;
PDBTitle: structure of the cytokine-like nuclear factor n-pac
32c3l6dB_



not modelled 99.6 12 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of putative oxidoreductase from pseudomonas putida2 kt2440
33c3ckyA_



not modelled 99.6 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-hydroxymethyl glutarate dehydrogenase;
PDBTitle: structural and kinetic properties of a beta-hydroxyacid dehydrogenase2 involved in nicotinate fermentation
34d1ybza1



not modelled 99.6 31 Fold:Chorismate mutase II
Superfamily:Chorismate mutase II
Family:Dimeric chorismate mutase
35c1np3B_



not modelled 99.6 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:ketol-acid reductoisomerase;
PDBTitle: crystal structure of class i acetohydroxy acid isomeroreductase from2 pseudomonas aeruginosa
36c3nvtA_



not modelled 99.6 27 PDB header:transferase/isomerase
Chain: A: PDB Molecule:3-deoxy-d-arabino-heptulosonate 7-phosphate synthase;
PDBTitle: 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7-2 phosphoheptulonate synthase/chorismate mutase (aroa) from listeria3 monocytogenes egd-e
37c1yb4A_



not modelled 99.6 11 PDB header:oxidoreductase
Chain: A: PDB Molecule:tartronic semialdehyde reductase;
PDBTitle: crystal structure of the tartronic semialdehyde reductase from2 salmonella typhimurium lt2
38c3pduF_



not modelled 99.6 12 PDB header:oxidoreductase
Chain: F: PDB Molecule:3-hydroxyisobutyrate dehydrogenase family protein;
PDBTitle: crystal structure of gamma-hydroxybutyrate dehydrogenase from2 geobacter sulfurreducens in complex with nadp+
39d3cuma2



not modelled 99.6 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
40c1vpdA_



not modelled 99.6 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:tartronate semialdehyde reductase;
PDBTitle: x-ray crystal structure of tartronate semialdehyde reductase2 [salmonella typhimurium lt2]
41c3g0oA_



not modelled 99.5 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-hydroxyisobutyrate dehydrogenase;
PDBTitle: crystal structure of 3-hydroxyisobutyrate dehydrogenase2 (ygbj) from salmonella typhimurium
42d2fp1a1



not modelled 99.5 28 Fold:Chorismate mutase II
Superfamily:Chorismate mutase II
Family:Secreted chorismate mutase-like
43c3fwnB_



not modelled 99.5 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:6-phosphogluconate dehydrogenase, decarboxylating;
PDBTitle: dimeric 6-phosphogluconate dehydrogenase complexed with 6-2 phosphogluconate and 2'-monophosphoadenosine-5'-diphosphate
44d2b0ja2



not modelled 99.5 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
45d2pgda2



not modelled 99.5 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
46c3qsgA_



not modelled 99.5 15 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:nad-binding phosphogluconate dehydrogenase-like protein;
PDBTitle: crystal structure of nad-binding phosphogluconate dehydrogenase-like2 protein from alicyclobacillus acidocaldarius
47c3pefA_



not modelled 99.5 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase, nad-binding;
PDBTitle: crystal structure of gamma-hydroxybutyrate dehydrogenase from2 geobacter metallireducens in complex with nadp+
48c2iz1C_



not modelled 99.5 21 PDB header:oxidoreductase
Chain: C: PDB Molecule:6-phosphogluconate dehydrogenase, decarboxylating;
PDBTitle: 6pdh complexed with pex inhibitor synchrotron data
49d1vpda2



not modelled 99.5 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
50c2p4qA_



not modelled 99.5 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase, decarboxylating 1;
PDBTitle: crystal structure analysis of gnd1 in saccharomyces cerevisiae
51d1f0ya2



not modelled 99.5 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
52c2y0dB_



not modelled 99.5 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:udp-glucose dehydrogenase;
PDBTitle: bcec mutation y10k
53c2gbbA_



not modelled 99.5 23 PDB header:isomerase
Chain: A: PDB Molecule:putative chorismate mutase;
PDBTitle: crystal structure of secreted chorismate mutase from2 yersinia pestis
54d1wdka3



not modelled 99.5 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
55c3hn2A_



not modelled 99.5 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-dehydropantoate 2-reductase;
PDBTitle: crystal structure of 2-dehydropantoate 2-reductase from geobacter2 metallireducens gs-15
56c2rafC_



not modelled 99.4 15 PDB header:oxidoreductase
Chain: C: PDB Molecule:putative dinucleotide-binding oxidoreductase;
PDBTitle: crystal structure of putative dinucleotide-binding2 oxidoreductase (np_786167.1) from lactobacillus plantarum3 at 1.60 a resolution
57c3dojA_



not modelled 99.4 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:dehydrogenase-like protein;
PDBTitle: structure of glyoxylate reductase 1 from arabidopsis2 (atglyr1)
58c2qbvA_



not modelled 99.4 23 PDB header:isomerase
Chain: A: PDB Molecule:chorismate mutase;
PDBTitle: crystal structure of intracellular chorismate mutase from2 mycobacterium tuberculosis
59c3qhaB_



not modelled 99.4 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of a putative oxidoreductase from mycobacterium2 avium 104
60c2i76B_



not modelled 99.4 17 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:hypothetical protein;
PDBTitle: crystal structure of protein tm1727 from thermotoga maritima
61c1pgjA_



not modelled 99.4 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase;
PDBTitle: x-ray structure of 6-phosphogluconate dehydrogenase from the protozoan2 parasite t. brucei
62d2cvza2



not modelled 99.4 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
63d1i36a2



not modelled 99.4 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
64c2vq3B_



not modelled 99.4 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:metalloreductase steap3;
PDBTitle: crystal structure of the membrane proximal oxidoreductase2 domain of human steap3, the dominant ferric reductase of3 the erythroid transferrin cycle
65d1jaya_



not modelled 99.3 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
66c3k96B_



not modelled 99.3 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:glycerol-3-phosphate dehydrogenase [nad(p)+];
PDBTitle: 2.1 angstrom resolution crystal structure of glycerol-3-phosphate2 dehydrogenase (gpsa) from coxiella burnetii
67c1mv8A_



not modelled 99.3 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:gdp-mannose 6-dehydrogenase;
PDBTitle: 1.55 a crystal structure of a ternary complex of gdp-mannose2 dehydrogenase from psuedomonas aeruginosa
68c3ojlA_



not modelled 99.3 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:cap5o;
PDBTitle: native structure of the udp-n-acetyl-mannosamine dehydrogenase cap5o2 from staphylococcus aureus
69c2cvzD_



not modelled 99.3 21 PDB header:oxidoreductase
Chain: D: PDB Molecule:3-hydroxyisobutyrate dehydrogenase;
PDBTitle: structure of hydroxyisobutyrate dehydrogenase from thermus2 thermophilus hb8
70c1m75B_



not modelled 99.3 19 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-hydroxyacyl-coa dehydrogenase;
PDBTitle: crystal structure of the n208s mutant of l-3-hydroxyacyl-2 coa dehydrogenase in complex with nad and acetoacetyl-coa
71c1pgqA_



not modelled 99.3 19 PDB header:oxidoreductase (choh(d)-nadp+(a))
Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase;
PDBTitle: crystallographic study of coenzyme, coenzyme analogue and substrate2 binding in 6-phosphogluconate dehydrogenase: implications for nadp3 specificity and the enzyme mechanism
72c3gg2B_



not modelled 99.3 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:sugar dehydrogenase, udp-glucose/gdp-mannose
PDBTitle: crystal structure of udp-glucose 6-dehydrogenase from2 porphyromonas gingivalis bound to product udp-glucuronate
73c3mogA_



not modelled 99.3 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable 3-hydroxybutyryl-coa dehydrogenase;
PDBTitle: crystal structure of 3-hydroxybutyryl-coa dehydrogenase from2 escherichia coli k12 substr. mg1655
74c3dttA_



not modelled 99.3 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadp oxidoreductase;
PDBTitle: crystal structure of a putative f420 dependent nadp-reductase2 (arth_0613) from arthrobacter sp. fb24 at 1.70 a resolution
75d1pgja2



not modelled 99.3 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
76c2ofpB_



not modelled 99.3 11 PDB header:oxidoreductase
Chain: B: PDB Molecule:ketopantoate reductase;
PDBTitle: crystal structure of escherichia coli ketopantoate2 reductase in a ternary complex with nadp+ and pantoate
77d2ahra2



not modelled 99.3 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
78c3k6jA_



not modelled 99.3 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:protein f01g10.3, confirmed by transcript evidence;
PDBTitle: crystal structure of the dehydrogenase part of multifuctional enzyme 12 from c.elegans
79d1txga2



not modelled 99.3 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
80c3plnA_



not modelled 99.2 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: crystal structure of klebsiella pneumoniae udp-glucose 6-dehydrogenase2 complexed with udp-glucose
81c2x58B_



not modelled 99.2 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:peroxisomal bifunctional enzyme;
PDBTitle: the crystal structure of mfe1 liganded with coa
82c2wtbA_



not modelled 99.2 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:fatty acid multifunctional protein (atmfp2);
PDBTitle: arabidopsis thaliana multifuctional protein, mfp2
83c2gf2B_



not modelled 99.2 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-hydroxyisobutyrate dehydrogenase;
PDBTitle: crystal structure of human hydroxyisobutyrate dehydrogenase
84c3g79A_



not modelled 99.2 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:ndp-n-acetyl-d-galactosaminuronic acid dehydrogenase;
PDBTitle: crystal structure of ndp-n-acetyl-d-galactosaminuronic acid2 dehydrogenase from methanosarcina mazei go1
85c1zcjA_



not modelled 99.2 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:peroxisomal bifunctional enzyme;
PDBTitle: crystal structure of 3-hydroxyacyl-coa dehydrogenase
86d1yqga2



not modelled 99.2 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
87c1ks9A_



not modelled 99.2 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-dehydropantoate 2-reductase;
PDBTitle: ketopantoate reductase from escherichia coli
88c2d3tB_



not modelled 99.1 14 PDB header:lyase, oxidoreductase/transferase
Chain: B: PDB Molecule:fatty oxidation complex alpha subunit;
PDBTitle: fatty acid beta-oxidation multienzyme complex from2 pseudomonas fragi, form v
89d1np3a2



not modelled 99.1 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
90c1dliA_



not modelled 99.1 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:udp-glucose dehydrogenase;
PDBTitle: the first structure of udp-glucose dehydrogenase (udpgdh) reveals the2 catalytic residues necessary for the two-fold oxidation
91c1txgA_



not modelled 99.1 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:glycerol-3-phosphate dehydrogenase [nad(p)+];
PDBTitle: structure of glycerol-3-phosphate dehydrogenase from archaeoglobus2 fulgidus
92c1wpqB_



not modelled 99.1 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:glycerol-3-phosphate dehydrogenase [nad+],
PDBTitle: ternary complex of glycerol 3-phosphate dehydrogenase 12 with nad and dihydroxyactone
93c1yj8C_



not modelled 99.1 15 PDB header:oxidoreductase
Chain: C: PDB Molecule:glycerol-3-phosphate dehydrogenase;
PDBTitle: initial structural analysis of plasmodium falciparum glycerol-3-2 phosphate dehydrogenase
94d1n1ea2



not modelled 99.1 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
95c2q3eH_



not modelled 99.1 16 PDB header:oxidoreductase
Chain: H: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: structure of human udp-glucose dehydrogenase complexed with nadh and2 udp-glucose
96d1mv8a2



not modelled 99.1 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
97c3hwrA_



not modelled 99.1 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-dehydropantoate 2-reductase;
PDBTitle: crystal structure of pane/apba family ketopantoate reductase2 (yp_299159.1) from ralstonia eutropha jmp134 at 2.15 a resolution
98c1zejA_



not modelled 99.1 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-hydroxyacyl-coa dehydrogenase;
PDBTitle: crystal structure of the 3-hydroxyacyl-coa dehydrogenase (hbd-9,2 af2017) from archaeoglobus fulgidus dsm 4304 at 2.00 a resolution
99d1bg6a2



not modelled 99.1 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
100d2i76a2



not modelled 99.0 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
101c3prjB_



not modelled 99.0 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: role of packing defects in the evolution of allostery and induced fit2 in human udp-glucose dehydrogenase.
102c2ew2B_



not modelled 99.0 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:2-dehydropantoate 2-reductase, putative;
PDBTitle: crystal structure of the putative 2-dehydropantoate 2-reductase from2 enterococcus faecalis
103c1m67A_



not modelled 99.0 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:glycerol-3-phosphate dehydrogenase;
PDBTitle: crystal structure of leishmania mexicana gpdh complexed with inhibitor2 2-bromo-6-hydroxy-purine
104c3dfuB_



not modelled 99.0 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:uncharacterized protein from 6-phosphogluconate
PDBTitle: crystal structure of a putative rossmann-like dehydrogenase (cgl2689)2 from corynebacterium glutamicum at 2.07 a resolution
105c1bg6A_



not modelled 99.0 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:n-(1-d-carboxylethyl)-l-norvaline dehydrogenase;
PDBTitle: crystal structure of the n-(1-d-carboxylethyl)-l-norvaline2 dehydrogenase from arthrobacter sp. strain 1c
106c2o3jC_



not modelled 99.0 18 PDB header:oxidoreductase
Chain: C: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: structure of caenorhabditis elegans udp-glucose dehydrogenase
107d1dlja2



not modelled 98.9 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
108c3hg7A_



not modelled 98.9 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-isomer specific 2-hydroxyacid dehydrogenase family
PDBTitle: crystal structure of d-isomer specific 2-hydroxyacid dehydrogenase2 family protein from aeromonas salmonicida subsp. salmonicida a449
109c3ghyA_



not modelled 98.9 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:ketopantoate reductase protein;
PDBTitle: crystal structure of a putative ketopantoate reductase from ralstonia2 solanacearum molk2
110c2rirA_



not modelled 98.9 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:dipicolinate synthase, a chain;
PDBTitle: crystal structure of dipicolinate synthase, a chain, from bacillus2 subtilis
111d1ygya1



not modelled 98.9 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
112c1z82A_



not modelled 98.8 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:glycerol-3-phosphate dehydrogenase;
PDBTitle: crystal structure of glycerol-3-phosphate dehydrogenase (tm0378) from2 thermotoga maritima at 2.00 a resolution
113c3bazA_



not modelled 98.8 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:hydroxyphenylpyruvate reductase;
PDBTitle: structure of hydroxyphenylpyruvate reductase from coleus blumei in2 complex with nadp+
114c3g17H_



not modelled 98.8 16 PDB header:structural genomics, unknown function
Chain: H: PDB Molecule:similar to 2-dehydropantoate 2-reductase;
PDBTitle: structure of putative 2-dehydropantoate 2-reductase from2 staphylococcus aureus
115c2omeA_



not modelled 98.8 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:c-terminal-binding protein 2;
PDBTitle: crystal structure of human ctbp2 dehydrogenase complexed with nad(h)
116c3c7cB_



not modelled 98.8 28 PDB header:oxidoreductase
Chain: B: PDB Molecule:octopine dehydrogenase;
PDBTitle: a structural basis for substrate and stereo selectivity in2 octopine dehydrogenase (odh-nadh-l-arginine)
117c2g76A_



not modelled 98.8 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-3-phosphoglycerate dehydrogenase;
PDBTitle: crystal structure of human 3-phosphoglycerate dehydrogenase
118c2dbqA_



not modelled 98.8 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:glyoxylate reductase;
PDBTitle: crystal structure of glyoxylate reductase (ph0597) from pyrococcus2 horikoshii ot3, complexed with nadp (i41)
119d1gdha1



not modelled 98.8 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
120c2cukC_



not modelled 98.8 19 PDB header:oxidoreductase
Chain: C: PDB Molecule:glycerate dehydrogenase/glyoxylate reductase;
PDBTitle: crystal structure of tt0316 protein from thermus thermophilus hb8

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0