Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	Q	Y	W	G	K	I	I	G	V	A	V	A	L	L	M	G	G	G	F	W	G	V	V	L	G	L	L	I	G	H	M	F	D	K	A	R	S	R	K	M	A	W	F	A	N	Q	R	E	R	Q	A	L	F	F	A	T	T	F	E
Secondary structure
SS confidence
Disorder		?	?	?	?																																		?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	M	G	H	L	T	K	S	K	G	R	V	T	E	A	D	I	H	I	A	S	Q	L	M	D	R	M	N	L	H	G	A	S	R	T	A	A	Q	N	A	F	R	V	G	K	S	D	N	Y	P	L	R	E	K	M	R	Q	F	R	S
Secondary structure
SS confidence
Disorder																													?	?																?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	C	F	G	R	F	D	L	I	R	M	F	L	E	I	Q	I	Q	A	A	F	A	D	G	S	L	H	P	N	E	R	A	V	L	Y	V	I	A	E	E	L	G	I	S	R	A	Q	F	D	Q	F	L	R	M	M	Q	G	G	A	Q
Secondary structure
SS confidence
Disorder																																																												?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		F	G	G	G	Y	Q	Q	Q	T	G	G	G	N	W	Q	Q	A	Q	R	G	P	T	L	E	D	A	C	N	V	L	G	V	K	P	T	D	D	A	T	T	I	K	R	A	Y	R	K	L	M	S	E	H	H	P	D	K	L	V	A	K
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																																			?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.
Sequence		G	L	P	P	E	M	M	E	M	A	K	Q	K	A	Q	E	I	Q	Q	A	Y	E	L	I	K	Q	Q	K	G	F	K
Secondary structure
SS confidence
Disorder		?	?	?																							?		?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2ou3 chain A domain 1 Region: 55 - 196 Aligned: 133 Modelled: 142 Confidence: 99.7% Identity: 17% Fold: TerB-like Superfamily: TerB-like Family: COG3793-like Phyre2 PDB 2jxu chain A Region: 50 - 169 Aligned: 120 Modelled: 120 Confidence: 99.7% Identity: 15% PDB header:unknown function Chain: A: PDB Molecule:terb; PDBTitle: nmr solution structure of kp-terb, a tellurite resistance2 protein from klebsiella pneumoniae Phyre2 PDB 3bvo chain A Region: 195 - 266 Aligned: 70 Modelled: 72 Confidence: 99.5% Identity: 14% PDB header:chaperone Chain: A: PDB Molecule:co-chaperone protein hscb, mitochondrial precursor; PDBTitle: crystal structure of human co-chaperone protein hscb Phyre2 PDB 1fpo chain A Region: 205 - 266 Aligned: 60 Modelled: 62 Confidence: 99.5% Identity: 22% PDB header:chaperone Chain: A: PDB Molecule:chaperone protein hscb; PDBTitle: hsc20 (hscb), a j-type co-chaperone from e. coli Phyre2 PDB 3hho chain A Region: 205 - 266 Aligned: 60 Modelled: 62 Confidence: 99.5% Identity: 23% PDB header:chaperone Chain: A: PDB Molecule:co-chaperone protein hscb homolog; PDBTitle: chaperone hscb from vibrio cholerae Phyre2 PDB 3apq chain B Region: 203 - 267 Aligned: 58 Modelled: 65 Confidence: 99.5% Identity: 31% PDB header:oxidoreductase Chain: B: PDB Molecule:dnaj homolog subfamily c member 10; PDBTitle: crystal structure of j-trx1 fragment of erdj5 Phyre2 PDB 2l6l chain A Region: 201 - 267 Aligned: 66 Modelled: 67 Confidence: 99.5% Identity: 30% PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily c member 24; PDBTitle: solution structure of human j-protein co-chaperone, dph4 Phyre2 PDB 1iur chain A Region: 191 - 267 Aligned: 71 Modelled: 77 Confidence: 99.5% Identity: 20% Fold: Long alpha-hairpin Superfamily: Chaperone J-domain Family: Chaperone J-domain Phyre2 PDB 1wjz chain A Region: 189 - 264 Aligned: 75 Modelled: 76 Confidence: 99.4% Identity: 32% Fold: Long alpha-hairpin Superfamily: Chaperone J-domain Family: Chaperone J-domain Phyre2 PDB 2ys8 chain A Region: 202 - 267 Aligned: 58 Modelled: 66 Confidence: 99.4% Identity: 33% PDB header:protein binding Chain: A: PDB Molecule:rab-related gtp-binding protein rabj; PDBTitle: solution structure of the dnaj-like domain from human ras-2 associated protein rap1 Phyre2 PDB 2ctq chain A Region: 197 - 268 Aligned: 65 Modelled: 72 Confidence: 99.3% Identity: 28% PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily c member 12; PDBTitle: solution structure of j-domain from human dnaj subfamily c2 menber 12 Phyre2 PDB 1gh6 chain A Region: 204 - 268 Aligned: 54 Modelled: 65 Confidence: 99.3% Identity: 22% Fold: Long alpha-hairpin Superfamily: Chaperone J-domain Family: Chaperone J-domain Phyre2 PDB 2guz chain O Region: 198 - 267 Aligned: 59 Modelled: 70 Confidence: 99.3% Identity: 22% PDB header:chaperone, protein transport Chain: O: PDB Molecule:mitochondrial import inner membrane translocase PDBTitle: structure of the tim14-tim16 complex of the mitochondrial2 protein import motor Phyre2 PDB 2yua chain A Region: 189 - 264 Aligned: 69 Modelled: 76 Confidence: 99.3% Identity: 26% PDB header:chaperone Chain: A: PDB Molecule:williams-beuren syndrome chromosome region 18 PDBTitle: solution structure of the dnaj domain from human williams-2 beuren syndrome chromosome region 18 protein Phyre2 PDB 2qsa chain A Region: 204 - 268 Aligned: 61 Modelled: 65 Confidence: 99.3% Identity: 33% PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog dnj-2; PDBTitle: crystal structure of j-domain of dnaj homolog dnj-2 precursor from2 c.elegans. Phyre2 PDB 2dmx chain A Region: 197 - 268 Aligned: 66 Modelled: 72 Confidence: 99.3% Identity: 33% PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily b member 8; PDBTitle: solution structure of the j domain of dnaj homolog2 subfamily b member 8 Phyre2 PDB 3ag7 chain A Region: 144 - 267 Aligned: 102 Modelled: 102 Confidence: 99.3% Identity: 25% PDB header:plant protein Chain: A: PDB Molecule:putative uncharacterized protein f9e10.5; PDBTitle: an auxilin-like j-domain containing protein, jac1 j-domain Phyre2 PDB 1fpo chain A domain 1 Region: 205 - 266 Aligned: 60 Modelled: 62 Confidence: 99.3% Identity: 22% Fold: Long alpha-hairpin Superfamily: Chaperone J-domain Family: Chaperone J-domain Phyre2 PDB 2ctw chain A Region: 191 - 268 Aligned: 71 Modelled: 78 Confidence: 99.3% Identity: 30% PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily c member 5; PDBTitle: solution structure of j-domain from mouse dnaj subfamily c2 menber 5 Phyre2 PDB 2ctr chain A Region: 199 - 266 Aligned: 60 Modelled: 68 Confidence: 99.3% Identity: 32% PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily b member 9; PDBTitle: solution structure of j-domain from human dnaj subfamily b2 menber 9 Phyre2 PDB 2iqc chain A Region: 6 - 147 Aligned: 133 Modelled: 133 Confidence: 59.6% Identity: 15% PDB header:protein binding Chain: A: PDB Molecule:fanconi anemia group f protein; PDBTitle: crystal structure of human fancf protein that functions in2 the assembly of a dna damage signaling complex Phyre2 1 d2ou3a1 2 c2jxuA_ 3 c3bvoA_ 4 c1fpoA_ 5 c3hhoA_ 6 c3apqB_ 7 c2l6lA_ 8 d1iura_ 9 d1wjza_ 10 c2ys8A_ 11 c2ctqA_ 12 d1gh6a_ 13 c2guzO_ 14 c2yuaA_ 15 c2qsaA_ 16 c2dmxA_ 17 c3ag7A_ 18 d1fpoa1 19 c2ctwA_ 20 c2ctrA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 c2iqcA_ 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d2ou3a1 99.7 17 Fold:TerB-like Superfamily:TerB-like Family:COG3793-like 2 c2jxuA_ 99.7 15 PDB header:unknown function Chain: A: PDB Molecule:terb; PDBTitle: nmr solution structure of kp-terb, a tellurite resistance2 protein from klebsiella pneumoniae 3 c3bvoA_ 99.5 14 PDB header:chaperone Chain: A: PDB Molecule:co-chaperone protein hscb, mitochondrial precursor; PDBTitle: crystal structure of human co-chaperone protein hscb 4 c1fpoA_ 99.5 22 PDB header:chaperone Chain: A: PDB Molecule:chaperone protein hscb; PDBTitle: hsc20 (hscb), a j-type co-chaperone from e. coli 5 c3hhoA_ 99.5 23 PDB header:chaperone Chain: A: PDB Molecule:co-chaperone protein hscb homolog; PDBTitle: chaperone hscb from vibrio cholerae 6 c3apqB_ 99.5 31 PDB header:oxidoreductase Chain: B: PDB Molecule:dnaj homolog subfamily c member 10; PDBTitle: crystal structure of j-trx1 fragment of erdj5 7 c2l6lA_ 99.5 30 PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily c member 24; PDBTitle: solution structure of human j-protein co-chaperone, dph4 8 d1iura_ 99.5 20 Fold:Long alpha-hairpin Superfamily:Chaperone J-domain Family:Chaperone J-domain 9 d1wjza_ 99.4 32 Fold:Long alpha-hairpin Superfamily:Chaperone J-domain Family:Chaperone J-domain 10 c2ys8A_ 99.4 33 PDB header:protein binding Chain: A: PDB Molecule:rab-related gtp-binding protein rabj; PDBTitle: solution structure of the dnaj-like domain from human ras-2 associated protein rap1 11 c2ctqA_ 99.3 28 PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily c member 12; PDBTitle: solution structure of j-domain from human dnaj subfamily c2 menber 12 12 d1gh6a_ 99.3 22 Fold:Long alpha-hairpin Superfamily:Chaperone J-domain Family:Chaperone J-domain 13 c2guzO_ 99.3 22 PDB header:chaperone, protein transport Chain: O: PDB Molecule:mitochondrial import inner membrane translocase PDBTitle: structure of the tim14-tim16 complex of the mitochondrial2 protein import motor 14 c2yuaA_ 99.3 26 PDB header:chaperone Chain: A: PDB Molecule:williams-beuren syndrome chromosome region 18 PDBTitle: solution structure of the dnaj domain from human williams-2 beuren syndrome chromosome region 18 protein 15 c2qsaA_ 99.3 33 PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog dnj-2; PDBTitle: crystal structure of j-domain of dnaj homolog dnj-2 precursor from2 c.elegans. 16 c2dmxA_ 99.3 33 PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily b member 8; PDBTitle: solution structure of the j domain of dnaj homolog2 subfamily b member 8 17 c3ag7A_ 99.3 25 PDB header:plant protein Chain: A: PDB Molecule:putative uncharacterized protein f9e10.5; PDBTitle: an auxilin-like j-domain containing protein, jac1 j-domain 18 d1fpoa1 99.3 22 Fold:Long alpha-hairpin Superfamily:Chaperone J-domain Family:Chaperone J-domain 19 c2ctwA_ 99.3 30 PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily c member 5; PDBTitle: solution structure of j-domain from mouse dnaj subfamily c2 menber 5 20 c2ctrA_ 99.3 32 PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily b member 9; PDBTitle: solution structure of j-domain from human dnaj subfamily b2 menber 9 21 c2lgwA_ not modelled 99.2 32 PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily b member 2; PDBTitle: solution structure of the j domain of hsj1a 22 c2kqxA_ not modelled 99.2 40 PDB header:chaperone binding protein Chain: A: PDB Molecule:curved dna-binding protein; PDBTitle: nmr structure of the j-domain (residues 2-72) in the2 escherichia coli cbpa 23 c2cugA_ not modelled 99.2 38 PDB header:chaperone Chain: A: PDB Molecule:mkiaa0962 protein; PDBTitle: solution structure of the j domain of the pseudo dnaj2 protein, mouse hypothetical mkiaa0962 24 d1fafa_ not modelled 99.2 23 Fold:Long alpha-hairpin Superfamily:Chaperone J-domain Family:Chaperone J-domain 25 c2ctpA_ not modelled 99.2 29 PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily b member 12; PDBTitle: solution structure of j-domain from human dnaj subfamily b2 menber 12 26 c2dn9A_ not modelled 99.2 30 PDB header:apoptosis, chaperone Chain: A: PDB Molecule:dnaj homolog subfamily a member 3; PDBTitle: solution structure of j-domain from the dnaj homolog, human2 tid1 protein 27 d1n4ca_ not modelled 99.2 27 Fold:Long alpha-hairpin Superfamily:Chaperone J-domain Family:Chaperone J-domain 28 d1nz6a_ not modelled 99.1 26 Fold:Long alpha-hairpin Superfamily:Chaperone J-domain Family:Chaperone J-domain 29 c2pf4E_ not modelled 99.1 21 PDB header:hydrolase regulator/viral protein Chain: E: PDB Molecule:small t antigen; PDBTitle: crystal structure of the full-length simian virus 40 small t antigen2 complexed with the protein phosphatase 2a aalpha subunit 30 d1hdja_ not modelled 99.1 35 Fold:Long alpha-hairpin Superfamily:Chaperone J-domain Family:Chaperone J-domain 31 d1xbla_ not modelled 99.1 33 Fold:Long alpha-hairpin Superfamily:Chaperone J-domain Family:Chaperone J-domain 32 c2o37A_ not modelled 99.1 31 PDB header:chaperone Chain: A: PDB Molecule:protein sis1; PDBTitle: j-domain of sis1 protein, hsp40 co-chaperone from2 saccharomyces cerevisiae. 33 c2ochA_ not modelled 99.1 38 PDB header:chaperone Chain: A: PDB Molecule:hypothetical protein dnj-12; PDBTitle: j-domain of dnj-12 from caenorhabditis elegans 34 c2guzD_ not modelled 99.0 18 PDB header:chaperone, protein transport Chain: D: PDB Molecule:mitochondrial import inner membrane translocase PDBTitle: structure of the tim14-tim16 complex of the mitochondrial2 protein import motor 35 c1bq0A_ not modelled 99.0 34 PDB header:chaperone Chain: A: PDB Molecule:dnaj; PDBTitle: j-domain (residues 1-77) of the escherichia coli n-terminal2 fragment (residues 1-104) of the molecular chaperone dnaj,3 nmr, 20 structures 36 c2y4tA_ not modelled 98.8 16 PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily c member 3; PDBTitle: crystal structure of the human co-chaperone p58(ipk) 37 c3uo2A_ not modelled 97.5 23 PDB header:chaperone Chain: A: PDB Molecule:j-type co-chaperone jac1, mitochondrial; PDBTitle: jac1 co-chaperone from saccharomyces cerevisiae 38 d2h5na1 not modelled 97.2 11 Fold:TerB-like Superfamily:TerB-like Family:PG1108-like 39 c3apoA_ not modelled 95.2 32 PDB header:oxidoreductase Chain: A: PDB Molecule:dnaj homolog subfamily c member 10; PDBTitle: crystal structure of full-length erdj5 40 d1ug2a_ not modelled 92.3 18 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:Myb/SANT domain 41 c3evrA_ not modelled 77.9 10 PDB header:signaling protein Chain: A: PDB Molecule:myosin light chain kinase, green fluorescent PDBTitle: crystal structure of calcium bound monomeric gcamp2 42 d2ouwa1 not modelled 75.9 20 Fold:AhpD-like Superfamily:AhpD-like Family:TTHA0727-like 43 d1aisb2 not modelled 73.1 17 Fold:Cyclin-like Superfamily:Cyclin-like Family:Transcription factor IIB (TFIIB), core domain 44 c2hpkA_ not modelled 69.3 13 PDB header:luminescent protein Chain: A: PDB Molecule:photoprotein berovin; PDBTitle: crystal structure of photoprotein berovin from beroe2 abyssicola 45 d2jxca1 not modelled 67.1 7 Fold:EF Hand-like Superfamily:EF-hand Family:Eps15 homology domain (EH domain) 46 d1vola2 not modelled 62.7 12 Fold:Cyclin-like Superfamily:Cyclin-like Family:Transcription factor IIB (TFIIB), core domain 47 c2iqcA_ 59.6 15 PDB header:protein binding Chain: A: PDB Molecule:fanconi anemia group f protein; PDBTitle: crystal structure of human fancf protein that functions in2 the assembly of a dna damage signaling complex 48 c2aucC_ not modelled 59.5 13 PDB header:membrane protein Chain: C: PDB Molecule:myosin a tail interacting protein; PDBTitle: structure of the plasmodium mtip-myoa complex, a key component of the2 parasite invasion motor 49 d1vola1 not modelled 53.9 12 Fold:Cyclin-like Superfamily:Cyclin-like Family:Transcription factor IIB (TFIIB), core domain 50 d1a04a1 not modelled 49.6 30 Fold:DNA/RNA-binding 3-helical bundle Superfamily:C-terminal effector domain of the bipartite response regulators Family:GerE-like (LuxR/UhpA family of transcriptional regulators) 51 c2q0oA_ not modelled 46.5 23 PDB header:transcription Chain: A: PDB Molecule:probable transcriptional activator protein trar; PDBTitle: crystal structure of an anti-activation complex in bacterial quorum2 sensing 52 c3k7aM_ not modelled 44.5 5 PDB header:transcription Chain: M: PDB Molecule:transcription initiation factor iib; PDBTitle: crystal structure of an rna polymerase ii-tfiib complex 53 c2kxaA_ not modelled 44.0 32 PDB header:viral protein, immune system Chain: A: PDB Molecule:haemagglutinin ha2 chain peptide; PDBTitle: the hemagglutinin fusion peptide (h1 subtype) at ph 7.4 54 c1h0mD_ not modelled 42.2 27 PDB header:transcription/dna Chain: D: PDB Molecule:transcriptional activator protein trar; PDBTitle: three-dimensional structure of the quorum sensing protein2 trar bound to its autoinducer and to its target dna 55 c2ggzB_ not modelled 41.2 13 PDB header:lyase activator Chain: B: PDB Molecule:guanylyl cyclase-activating protein 3; PDBTitle: crystal structure of human guanylate cyclase activating2 protein-3 56 c2kfhA_ not modelled 39.7 18 PDB header:protein binding Chain: A: PDB Molecule:eh domain-containing protein 1; PDBTitle: structure of the c-terminal domain of ehd1 with fnyestgpftak 57 d1aisb1 not modelled 39.4 18 Fold:Cyclin-like Superfamily:Cyclin-like Family:Transcription factor IIB (TFIIB), core domain 58 c2in3A_ not modelled 38.9 14 PDB header:isomerase Chain: A: PDB Molecule:hypothetical protein; PDBTitle: crystal structure of a putative protein disulfide isomerase from2 nitrosomonas europaea 59 c3hugJ_ not modelled 38.7 25 PDB header:transcription/membrane protein Chain: J: PDB Molecule:probable conserved membrane protein; PDBTitle: crystal structure of mycobacterium tuberculosis anti-sigma factor rsla2 in complex with -35 promoter binding domain of sigl 60 c1yzxB_ not modelled 38.5 13 PDB header:transferase Chain: B: PDB Molecule:glutathione s-transferase kappa 1; PDBTitle: crystal structure of human kappa class glutathione2 transferase 61 d1fi6a_ not modelled 37.1 16 Fold:EF Hand-like Superfamily:EF-hand Family:Eps15 homology domain (EH domain) 62 c3fiaA_ not modelled 37.0 9 PDB header:protein binding Chain: A: PDB Molecule:intersectin-1; PDBTitle: crystal structure of the eh 1 domain from human intersectin-2 1 protein. northeast structural genomics consortium target3 hr3646e. 63 d1rioa_ not modelled 36.6 15 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:Phage repressors 64 d1c07a_ not modelled 36.5 7 Fold:EF Hand-like Superfamily:EF-hand Family:Eps15 homology domain (EH domain) 65 c3kzqE_ not modelled 35.1 19 PDB header:structural genomics, unknown function Chain: E: PDB Molecule:putative uncharacterized protein vp2116; PDBTitle: the crystal structure of the protein with unknown function from vibrio2 parahaemolyticus rimd 2210633 66 d1vkea_ not modelled 34.4 17 Fold:AhpD-like Superfamily:AhpD-like Family:CMD-like 67 c3oouA_ not modelled 34.3 10 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:lin2118 protein; PDBTitle: the structure of a protein with unkown function from listeria innocua 68 d1p4wa_ not modelled 34.2 23 Fold:DNA/RNA-binding 3-helical bundle Superfamily:C-terminal effector domain of the bipartite response regulators Family:GerE-like (LuxR/UhpA family of transcriptional regulators) 69 d1r4wa_ not modelled 34.2 14 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:DsbA-like 70 d2mysb_ not modelled 34.0 10 Fold:EF Hand-like Superfamily:EF-hand Family:Calmodulin-like 71 c2pmyB_ not modelled 33.9 18 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:ras and ef-hand domain-containing protein; PDBTitle: ef-hand domain of human rasef 72 d1v4wa_ not modelled 33.1 9 Fold:Globin-like Superfamily:Globin-like Family:Globins 73 c3ek7A_ not modelled 32.2 13 PDB header:fluorescent protein Chain: A: PDB Molecule:myosin light chain kinase, green fluorescent PDBTitle: calcium-saturated gcamp2 dimer 74 c1w8jD_ not modelled 32.0 19 PDB header:motor protein Chain: D: PDB Molecule:myosin va; PDBTitle: crystal structure of myosin v motor domain -2 nucleotide-free 75 c2hg5D_ not modelled 32.0 24 PDB header:membrane protein Chain: D: PDB Molecule:kcsa channel; PDBTitle: cs+ complex of a k channel with an amide to ester substitution in the2 selectivity filter 76 c1o17A_ not modelled 30.9 16 PDB header:transferase Chain: A: PDB Molecule:anthranilate phosphoribosyltransferase; PDBTitle: anthranilate phosphoribosyl-transferase (trpd) 77 c3mseB_ not modelled 30.4 11 PDB header:transferase Chain: B: PDB Molecule:calcium-dependent protein kinase, putative; PDBTitle: crystal structure of c-terminal domain of pf110239. 78 c3ivpD_ not modelled 30.0 17 PDB header:dna binding protein Chain: D: PDB Molecule:putative transposon-related dna-binding protein; PDBTitle: the structure of a possible transposon-related dna-binding protein2 from clostridium difficile 630. 79 d3e11a1 not modelled 29.1 26 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:TTHA0227-like 80 c3j04A_ not modelled 29.1 10 PDB header:structural protein Chain: A: PDB Molecule:myosin-11; PDBTitle: em structure of the heavy meromyosin subfragment of chick smooth2 muscle myosin with regulatory light chain in phosphorylated state 81 c2doqA_ not modelled 29.0 7 PDB header:cell cycle Chain: A: PDB Molecule:cell division control protein 31; PDBTitle: crystal structure of sfi1p/cdc31p complex 82 c3t76A_ not modelled 28.9 20 PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator vanug; PDBTitle: crystal structure of transcriptional regulator vanug, form ii 83 c2rmrA_ not modelled 28.7 15 PDB header:transcription Chain: A: PDB Molecule:paired amphipathic helix protein sin3a; PDBTitle: solution structure of msin3a pah1 domain 84 c2otgA_ not modelled 28.3 11 PDB header:contractile protein Chain: A: PDB Molecule:myosin heavy chain; PDBTitle: rigor-like structures of muscle myosins reveal key2 mechanical elements in the transduction pathways of this3 allosteric motor 85 c1p8cD_ not modelled 28.2 16 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:conserved hypothetical protein; PDBTitle: crystal structure of tm1620 (apc4843) from thermotoga2 maritima 86 c1eg4A_ not modelled 27.0 14 PDB header:structural protein Chain: A: PDB Molecule:dystrophin; PDBTitle: structure of a dystrophin ww domain fragment in complex2 with a beta-dystroglycan peptide 87 d1qjta_ not modelled 26.7 18 Fold:EF Hand-like Superfamily:EF-hand Family:Eps15 homology domain (EH domain) 88 c3eusB_ not modelled 25.7 10 PDB header:dna binding protein Chain: B: PDB Molecule:dna-binding protein; PDBTitle: the crystal structure of the dna binding protein from silicibacter2 pomeroyi 89 c2bl0C_ not modelled 25.3 9 PDB header:muscle protein Chain: C: PDB Molecule:myosin regulatory light chain; PDBTitle: physarum polycephalum myosin ii regulatory domain 90 c2kvcA_ not modelled 25.1 7 PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: solution structure of the mycobacterium tuberculosis protein rv0543c,2 a member of the duf3349 superfamily. seattle structural genomics3 center for infectious disease target mytud.17112.a 91 d1sq8a_ not modelled 25.1 41 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:Phage repressors 92 d1ha7a_ not modelled 24.8 12 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins 93 d1b33b_ not modelled 24.6 14 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins 94 c2kgrA_ not modelled 24.6 12 PDB header:protein binding Chain: A: PDB Molecule:intersectin-1; PDBTitle: solution structure of protein itsn1 from homo sapiens.2 northeast structural genomics consortium target hr5524a 95 d1allb_ not modelled 24.4 15 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins 96 c2dfsA_ not modelled 24.4 19 PDB header:contractile protein/transport protein Chain: A: PDB Molecule:myosin-5a; PDBTitle: 3-d structure of myosin-v inhibited state 97 c3f6wE_ not modelled 23.9 16 PDB header:dna binding protein Chain: E: PDB Molecule:xre-family like protein; PDBTitle: xre-family like protein from pseudomonas syringae pv. tomato str.2 dc3000 98 c1i84V_ not modelled 22.9 10 PDB header:contractile protein Chain: V: PDB Molecule:smooth muscle myosin heavy chain; PDBTitle: cryo-em structure of the heavy meromyosin subfragment of2 chicken gizzard smooth muscle myosin with regulatory light3 chain in the dephosphorylated state. only c alphas4 provided for regulatory light chain. only backbone atoms5 provided for s2 fragment. 99 d2croa_ not modelled 22.8 34 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:Phage repressors 100 d1jeba_ not modelled 22.2 11 Fold:Globin-like Superfamily:Globin-like Family:Globins 101 c3d7iB_ not modelled 21.7 21 PDB header:lyase Chain: B: PDB Molecule:carboxymuconolactone decarboxylase family protein; PDBTitle: crystal structure of carboxymuconolactone decarboxylase family protein2 possibly involved in oxygen detoxification (1591455) from3 methanococcus jannaschii at 1.75 a resolution 102 c3k69A_ not modelled 21.6 15 PDB header:transcription Chain: A: PDB Molecule:putative transcription regulator; PDBTitle: crystal structure of a putative transcriptional regulator (lp_0360)2 from lactobacillus plantarum at 1.95 a resolution 103 d2gqba1 not modelled 21.6 31 Fold:RPA2825-like Superfamily:RPA2825-like Family:RPA2825-like 104 c3op9A_ not modelled 21.5 11 PDB header:transcription regulator Chain: A: PDB Molecule:pli0006 protein; PDBTitle: crystal structure of transcriptional regulator from listeria innocua 105 c3trbA_ not modelled 21.4 19 PDB header:dna binding protein Chain: A: PDB Molecule:virulence-associated protein i; PDBTitle: structure of an addiction module antidote protein of a higa (higa)2 family from coxiella burnetii 106 d1wdcb_ not modelled 21.4 8 Fold:EF Hand-like Superfamily:EF-hand Family:Calmodulin-like 107 d1ffva1 not modelled 21.3 21 Fold:CO dehydrogenase ISP C-domain like Superfamily:CO dehydrogenase ISP C-domain like Family:CO dehydrogenase ISP C-domain like 108 c3sibA_ not modelled 21.3 11 PDB header:dna binding protein Chain: A: PDB Molecule:ure3-bp sequence specific dna binding protein; PDBTitle: crystal structure of ure3-binding protein, wild-type 109 c2gbbA_ not modelled 21.2 16 PDB header:isomerase Chain: A: PDB Molecule:putative chorismate mutase; PDBTitle: crystal structure of secreted chorismate mutase from2 yersinia pestis 110 d1n62a1 not modelled 20.7 18 Fold:CO dehydrogenase ISP C-domain like Superfamily:CO dehydrogenase ISP C-domain like Family:CO dehydrogenase ISP C-domain like 111 c2ebyA_ not modelled 20.7 14 PDB header:transcription Chain: A: PDB Molecule:putative hth-type transcriptional regulator ybaq; PDBTitle: crystal structure of a hypothetical protein from e. coli 112 c1br4E_ not modelled 20.2 10 PDB header:muscle protein Chain: E: PDB Molecule:myosin; PDBTitle: smooth muscle myosin motor domain-essential light chain2 complex with mgadp.bef3 bound at the active site 113 d1b8da_ not modelled 20.1 8 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins 114 d1f99a_ not modelled 20.0 12 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0