Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	F	K	K	I	L	F	P	L	V	A	L	F	M	L	A	G	C	A	K	P	P	T	T	I	E	V	S	P	T	I	T	L	P	Q	Q	D	P	S	L	M	G	V	T	V	S	I	N	G	A	D	Q	R	T	D	Q	A	L	A	K
Secondary structure
SS confidence
Disorder		?	?																				?	?					?	?	?	?	?	?	?	?	?	?	?	?	?	?	?										?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	T	R	D	N	Q	I	V	T	L	T	A	S	R	D	L	R	F	L	L	Q	E	V	L	E	K	Q	M	T	A	R	G	Y	M	V	G	P	N	G	P	V	N	L	Q	I	I	V	S	Q	L	Y	A	D	V	S	Q	G	N	V	R
Secondary structure
SS confidence
Disorder																																?	?			?					?																	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		Y	N	I	A	T	K	A	D	I	A	I	I	A	T	A	Q	N	G	N	K	M	T	K	N	Y	R	A	S	Y	N	V	E	G	A	F	Q	A	S	N	K	N	I	A	D	A	V	N	S	V	L	T	D	T	I	A	D	M	S	Q	D
Secondary structure
SS confidence
Disorder																	?	?	?	?								?	?	?				?	?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.
Sequence		T	S	I	H	E	F	I	K	Q	N	A	R
Secondary structure
SS confidence
Disorder											?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2iqi chain A domain 1 Region: 26 - 178 Aligned: 148 Modelled: 153 Confidence: 97.6% Identity: 12% Fold: Anticodon-binding domain-like Superfamily: XCC0632-like Family: XCC0632-like Phyre2 PDB 2k7r chain A Region: 166 - 190 Aligned: 25 Modelled: 25 Confidence: 85.6% Identity: 20% PDB header:replication Chain: A: PDB Molecule:primosomal protein dnai; PDBTitle: n-terminal domain of the bacillus subtilis helicase-loading2 protein dnai Phyre2 PDB 2r76 chain A Region: 71 - 178 Aligned: 108 Modelled: 108 Confidence: 81.9% Identity: 6% PDB header:lipoprotein Chain: A: PDB Molecule:rare lipoprotein b; PDBTitle: crystal structure of the rare lipoprotein b (so_1173) from shewanella2 oneidensis, northeast structural genomics consortium target sor91a Phyre2 PDB 3qhp chain B Region: 167 - 192 Aligned: 26 Modelled: 26 Confidence: 46.6% Identity: 12% PDB header:transferase Chain: B: PDB Molecule:type 1 capsular polysaccharide biosynthesis protein j PDBTitle: crystal structure of the catalytic domain of cholesterol-alpha-2 glucosyltransferase from helicobacter pylori Phyre2 PDB 2iw1 chain A domain 1 Region: 168 - 192 Aligned: 25 Modelled: 25 Confidence: 45.2% Identity: 16% Fold: UDP-Glycosyltransferase/glycogen phosphorylase Superfamily: UDP-Glycosyltransferase/glycogen phosphorylase Family: Glycosyl transferases group 1 Phyre2 PDB 2jxp chain A Region: 80 - 178 Aligned: 99 Modelled: 99 Confidence: 41.9% Identity: 9% PDB header:lipoprotein Chain: A: PDB Molecule:putative lipoprotein b; PDBTitle: solution nmr structure of uncharacterized lipoprotein b2 from nitrosomonas europaea. northeast structural genomics3 target ner45a Phyre2 PDB 3iaa chain B Region: 168 - 192 Aligned: 25 Modelled: 23 Confidence: 41.8% Identity: 8% PDB header:transferase Chain: B: PDB Molecule:calg2; PDBTitle: crystal structure of calg2, calicheamicin glycosyltransferase, tdp2 bound form Phyre2 PDB 2iyf chain A Region: 168 - 192 Aligned: 25 Modelled: 25 Confidence: 36.9% Identity: 12% PDB header:transferase Chain: A: PDB Molecule:oleandomycin glycosyltransferase; PDBTitle: the crystal structure of macrolide glycosyltransferases: a2 blueprint for antibiotic engineering Phyre2 PDB 3ia7 chain A Region: 168 - 192 Aligned: 25 Modelled: 22 Confidence: 36.5% Identity: 12% PDB header:transferase Chain: A: PDB Molecule:calg4; PDBTitle: crystal structure of calg4, the calicheamicin glycosyltransferase Phyre2 PDB 2bfw chain A domain 1 Region: 167 - 192 Aligned: 26 Modelled: 26 Confidence: 36.0% Identity: 15% Fold: UDP-Glycosyltransferase/glycogen phosphorylase Superfamily: UDP-Glycosyltransferase/glycogen phosphorylase Family: Glycosyl transferases group 1 Phyre2 PDB 2kw3 chain C Region: 165 - 189 Aligned: 25 Modelled: 25 Confidence: 35.7% Identity: 12% PDB header:dna binding protein Chain: C: PDB Molecule:regulatory factor x-associated protein; PDBTitle: heterotrimeric interaction between rfx5 and rfxap Phyre2 PDB 2r60 chain A Region: 168 - 192 Aligned: 25 Modelled: 25 Confidence: 35.3% Identity: 0% PDB header:transferase Chain: A: PDB Molecule:glycosyl transferase, group 1; PDBTitle: structure of apo sucrose phosphate synthase (sps) of2 halothermothrix orenii Phyre2 PDB 3oka chain A Region: 168 - 192 Aligned: 25 Modelled: 25 Confidence: 34.4% Identity: 12% PDB header:transferase Chain: A: PDB Molecule:gdp-mannose-dependent alpha-(1-6)-phosphatidylinositol PDBTitle: crystal structure of corynebacterium glutamicum pimb' in complex with2 gdp-man (triclinic crystal form) Phyre2 PDB 3c4v chain B Region: 168 - 192 Aligned: 25 Modelled: 25 Confidence: 30.8% Identity: 16% PDB header:transferase Chain: B: PDB Molecule:predicted glycosyltransferases; PDBTitle: structure of the retaining glycosyltransferase msha:the2 first step in mycothiol biosynthesis. organism:3 corynebacterium glutamicum : complex with udp and 1l-ins-1-4 p. Phyre2 PDB 2iya chain B Region: 168 - 192 Aligned: 25 Modelled: 25 Confidence: 29.8% Identity: 12% PDB header:transferase Chain: B: PDB Molecule:oleandomycin glycosyltransferase; PDBTitle: the crystal structure of macrolide glycosyltransferases: a2 blueprint for antibiotic engineering Phyre2 PDB 2jjm chain H Region: 168 - 192 Aligned: 25 Modelled: 25 Confidence: 29.3% Identity: 20% PDB header:transferase Chain: H: PDB Molecule:glycosyl transferase, group 1 family protein; PDBTitle: crystal structure of a family gt4 glycosyltransferase from2 bacillus anthracis orf ba1558. Phyre2 PDB 3dzc chain A Region: 168 - 192 Aligned: 25 Modelled: 25 Confidence: 28.9% Identity: 12% PDB header:isomerase Chain: A: PDB Molecule:udp-n-acetylglucosamine 2-epimerase; PDBTitle: 2.35 angstrom resolution structure of wecb (vc0917), a udp-n-2 acetylglucosamine 2-epimerase from vibrio cholerae. Phyre2 PDB 2xmp chain B Region: 168 - 192 Aligned: 25 Modelled: 25 Confidence: 25.6% Identity: 4% PDB header:sugar binding protein Chain: B: PDB Molecule:trehalose-synthase tret; PDBTitle: crystal structure of trehalose synthase tret mutant e326a2 from p.horishiki in complex with udp Phyre2 PDB 2gej chain A Region: 168 - 192 Aligned: 25 Modelled: 25 Confidence: 25.2% Identity: 8% PDB header:transferase Chain: A: PDB Molecule:phosphatidylinositol mannosyltransferase (pima); PDBTitle: crystal structure of phosphatidylinositol mannosyltransferase (pima)2 from mycobacterium smegmatis in complex with gdp-man Phyre2 PDB 2fu2 chain A Region: 157 - 191 Aligned: 33 Modelled: 35 Confidence: 24.5% Identity: 27% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein spy2152; PDBTitle: crystal structure of protein spy2152 from streptococcus pyogenes Phyre2 1 d2iqia1 2 c2k7rA_ 3 c2r76A_ 4 c3qhpB_ 5 d2iw1a1 6 c2jxpA_ 7 c3iaaB_ 8 c2iyfA_ 9 c3ia7A_ 10 d2bfwa1 11 c2kw3C_ 12 c2r60A_ 13 c3okaA_ 14 c3c4vB_ 15 c2iyaB_ 16 c2jjmH_ 17 c3dzcA_ 18 c2xmpB_ 19 c2gejA_ 20 c2fu2A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d2iqia1 97.6 12 Fold:Anticodon-binding domain-like Superfamily:XCC0632-like Family:XCC0632-like 2 c2k7rA_ 85.6 20 PDB header:replication Chain: A: PDB Molecule:primosomal protein dnai; PDBTitle: n-terminal domain of the bacillus subtilis helicase-loading2 protein dnai 3 c2r76A_ 81.9 6 PDB header:lipoprotein Chain: A: PDB Molecule:rare lipoprotein b; PDBTitle: crystal structure of the rare lipoprotein b (so_1173) from shewanella2 oneidensis, northeast structural genomics consortium target sor91a 4 c3qhpB_ 46.6 12 PDB header:transferase Chain: B: PDB Molecule:type 1 capsular polysaccharide biosynthesis protein j PDBTitle: crystal structure of the catalytic domain of cholesterol-alpha-2 glucosyltransferase from helicobacter pylori 5 d2iw1a1 45.2 16 Fold:UDP-Glycosyltransferase/glycogen phosphorylase Superfamily:UDP-Glycosyltransferase/glycogen phosphorylase Family:Glycosyl transferases group 1 6 c2jxpA_ 41.9 9 PDB header:lipoprotein Chain: A: PDB Molecule:putative lipoprotein b; PDBTitle: solution nmr structure of uncharacterized lipoprotein b2 from nitrosomonas europaea. northeast structural genomics3 target ner45a 7 c3iaaB_ 41.8 8 PDB header:transferase Chain: B: PDB Molecule:calg2; PDBTitle: crystal structure of calg2, calicheamicin glycosyltransferase, tdp2 bound form 8 c2iyfA_ 36.9 12 PDB header:transferase Chain: A: PDB Molecule:oleandomycin glycosyltransferase; PDBTitle: the crystal structure of macrolide glycosyltransferases: a2 blueprint for antibiotic engineering 9 c3ia7A_ 36.5 12 PDB header:transferase Chain: A: PDB Molecule:calg4; PDBTitle: crystal structure of calg4, the calicheamicin glycosyltransferase 10 d2bfwa1 36.0 15 Fold:UDP-Glycosyltransferase/glycogen phosphorylase Superfamily:UDP-Glycosyltransferase/glycogen phosphorylase Family:Glycosyl transferases group 1 11 c2kw3C_ 35.7 12 PDB header:dna binding protein Chain: C: PDB Molecule:regulatory factor x-associated protein; PDBTitle: heterotrimeric interaction between rfx5 and rfxap 12 c2r60A_ 35.3 0 PDB header:transferase Chain: A: PDB Molecule:glycosyl transferase, group 1; PDBTitle: structure of apo sucrose phosphate synthase (sps) of2 halothermothrix orenii 13 c3okaA_ 34.4 12 PDB header:transferase Chain: A: PDB Molecule:gdp-mannose-dependent alpha-(1-6)-phosphatidylinositol PDBTitle: crystal structure of corynebacterium glutamicum pimb' in complex with2 gdp-man (triclinic crystal form) 14 c3c4vB_ 30.8 16 PDB header:transferase Chain: B: PDB Molecule:predicted glycosyltransferases; PDBTitle: structure of the retaining glycosyltransferase msha:the2 first step in mycothiol biosynthesis. organism:3 corynebacterium glutamicum : complex with udp and 1l-ins-1-4 p. 15 c2iyaB_ 29.8 12 PDB header:transferase Chain: B: PDB Molecule:oleandomycin glycosyltransferase; PDBTitle: the crystal structure of macrolide glycosyltransferases: a2 blueprint for antibiotic engineering 16 c2jjmH_ 29.3 20 PDB header:transferase Chain: H: PDB Molecule:glycosyl transferase, group 1 family protein; PDBTitle: crystal structure of a family gt4 glycosyltransferase from2 bacillus anthracis orf ba1558. 17 c3dzcA_ 28.9 12 PDB header:isomerase Chain: A: PDB Molecule:udp-n-acetylglucosamine 2-epimerase; PDBTitle: 2.35 angstrom resolution structure of wecb (vc0917), a udp-n-2 acetylglucosamine 2-epimerase from vibrio cholerae. 18 c2xmpB_ 25.6 4 PDB header:sugar binding protein Chain: B: PDB Molecule:trehalose-synthase tret; PDBTitle: crystal structure of trehalose synthase tret mutant e326a2 from p.horishiki in complex with udp 19 c2gejA_ 25.2 8 PDB header:transferase Chain: A: PDB Molecule:phosphatidylinositol mannosyltransferase (pima); PDBTitle: crystal structure of phosphatidylinositol mannosyltransferase (pima)2 from mycobacterium smegmatis in complex with gdp-man 20 c2fu2A_ 24.5 27 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein spy2152; PDBTitle: crystal structure of protein spy2152 from streptococcus pyogenes 21 c2x6rA_ not modelled 22.5 4 PDB header:isomerase Chain: A: PDB Molecule:trehalose-synthase tret; PDBTitle: crystal structure of trehalose synthase tret from p.2 horikoshi produced by soaking in trehalose 22 c3bf2A_ not modelled 20.5 9 PDB header:lipoprotein Chain: A: PDB Molecule:putative lipoprotein; PDBTitle: crystal structure of the a1ksw9_neimf protein from2 neisseria meningitidis. northeast structural genomics3 consortium target mr36a 23 c3othB_ not modelled 20.0 8 PDB header:transferase/antibiotic Chain: B: PDB Molecule:calg1; PDBTitle: crystal structure of calg1, calicheamicin glycostyltransferase, tdp2 and calicheamicin alpha3i bound form 24 d1o6ca_ not modelled 18.3 8 Fold:UDP-Glycosyltransferase/glycogen phosphorylase Superfamily:UDP-Glycosyltransferase/glycogen phosphorylase Family:UDP-N-acetylglucosamine 2-epimerase 25 c3s29C_ not modelled 18.1 20 PDB header:transferase Chain: C: PDB Molecule:sucrose synthase 1; PDBTitle: the crystal structure of sucrose synthase-1 from arabidopsis thaliana2 and its functional implications. 26 c2p6pB_ not modelled 17.0 8 PDB header:transferase Chain: B: PDB Molecule:glycosyl transferase; PDBTitle: x-ray crystal structure of c-c bond-forming dtdp-d-olivose-transferase2 urdgt2 27 d2ijra1 not modelled 15.1 71 Fold:Api92-like Superfamily:Api92-like Family:Api92-like 28 c2qpqC_ not modelled 15.0 26 PDB header:transport protein Chain: C: PDB Molecule:protein bug27; PDBTitle: structure of bug27 from bordetella pertussis 29 c2kw0A_ not modelled 14.5 14 PDB header:oxidoreductase Chain: A: PDB Molecule:ccmh protein; PDBTitle: solution structure of n-terminal domain of ccmh from escherichia.coli 30 d1f6da_ not modelled 14.3 4 Fold:UDP-Glycosyltransferase/glycogen phosphorylase Superfamily:UDP-Glycosyltransferase/glycogen phosphorylase Family:UDP-N-acetylglucosamine 2-epimerase 31 d1v4va_ not modelled 13.6 0 Fold:UDP-Glycosyltransferase/glycogen phosphorylase Superfamily:UDP-Glycosyltransferase/glycogen phosphorylase Family:UDP-N-acetylglucosamine 2-epimerase 32 c2hl7A_ not modelled 13.3 17 PDB header:oxidoreductase Chain: A: PDB Molecule:cytochrome c-type biogenesis protein ccmh; PDBTitle: crystal structure of the periplasmic domain of ccmh from pseudomonas2 aeruginosa 33 d2f9fa1 not modelled 12.3 12 Fold:UDP-Glycosyltransferase/glycogen phosphorylase Superfamily:UDP-Glycosyltransferase/glycogen phosphorylase Family:Glycosyl transferases group 1 34 c3ot5D_ not modelled 11.7 20 PDB header:isomerase Chain: D: PDB Molecule:udp-n-acetylglucosamine 2-epimerase; PDBTitle: 2.2 angstrom resolution crystal structure of putative udp-n-2 acetylglucosamine 2-epimerase from listeria monocytogenes 35 c2dvzA_ not modelled 11.5 15 PDB header:transport protein Chain: A: PDB Molecule:putative exported protein; PDBTitle: structure of a periplasmic transporter 36 c3iq2B_ not modelled 10.9 17 PDB header:protein transport Chain: B: PDB Molecule:sorting nexin-7; PDBTitle: human sorting nexin 7, phox homology (px) domain 37 c2cskA_ not modelled 10.1 10 PDB header:protein transport Chain: A: PDB Molecule:sorting nexin 12; PDBTitle: solution structure of px domain from human snx12 38 d1m6ex_ not modelled 9.5 33 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Salicylic acid carboxyl methyltransferase (SAMT) 39 c2f5xC_ not modelled 9.1 23 PDB header:transport protein Chain: C: PDB Molecule:bugd; PDBTitle: structure of periplasmic binding protein bugd 40 c3b5iB_ not modelled 8.7 33 PDB header:transferase Chain: B: PDB Molecule:s-adenosyl-l-methionine:salicylic acid carboxyl PDBTitle: crystal structure of indole-3-acetic acid methyltransferase 41 c3d0qB_ not modelled 8.2 13 PDB header:transferase Chain: B: PDB Molecule:protein calg3; PDBTitle: crystal structure of calg3 from micromonospora echinospora determined2 in space group i222 42 c3kjlG_ not modelled 7.5 36 PDB header:transcription Chain: G: PDB Molecule:saga-associated factor 11; PDBTitle: sgf11:sus1 complex 43 d1kmda_ not modelled 7.4 7 Fold:PX domain Superfamily:PX domain Family:PX domain 44 d1pvea_ not modelled 7.2 17 Fold:XPC-binding domain Superfamily:XPC-binding domain Family:XPC-binding domain 45 c3kikE_ not modelled 7.0 36 PDB header:transcription Chain: E: PDB Molecule:saga-associated factor 11; PDBTitle: sgf11:sus1 complex 46 c3kikF_ not modelled 7.0 36 PDB header:transcription Chain: F: PDB Molecule:saga-associated factor 11; PDBTitle: sgf11:sus1 complex 47 c3kikH_ not modelled 6.9 36 PDB header:transcription Chain: H: PDB Molecule:saga-associated factor 11; PDBTitle: sgf11:sus1 complex 48 c2eg5C_ not modelled 6.7 56 PDB header:transferase Chain: C: PDB Molecule:xanthosine methyltransferase; PDBTitle: the structure of xanthosine methyltransferase 49 c1xteA_ not modelled 6.7 4 PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase sgk3; PDBTitle: crystal structure of cisk-px domain 50 d1xtea_ not modelled 6.7 4 Fold:PX domain Superfamily:PX domain Family:PX domain 51 c3kikG_ not modelled 6.7 36 PDB header:transcription Chain: G: PDB Molecule:saga-associated factor 11; PDBTitle: sgf11:sus1 complex 52 c1x3wB_ not modelled 6.6 21 PDB header:hydrolase Chain: B: PDB Molecule:uv excision repair protein rad23; PDBTitle: structure of a peptide:n-glycanase-rad23 complex 53 c3fogA_ not modelled 6.5 7 PDB header:protein transport Chain: A: PDB Molecule:sorting nexin-17; PDBTitle: crystal structure of the px domain of sorting nexin-172 (snx17) 54 d2f4mb1 not modelled 6.3 17 Fold:XPC-binding domain Superfamily:XPC-binding domain Family:XPC-binding domain 55 c2i4kA_ not modelled 6.3 17 PDB header:protein transport Chain: A: PDB Molecule:sorting nexin-1; PDBTitle: solution structure of the px domain of sorting nexin 1 56 c3onoA_ not modelled 6.3 7 PDB header:isomerase Chain: A: PDB Molecule:ribose/galactose isomerase; PDBTitle: crystal structure of ribose-5-phosphate isomerase lacab_rpib from2 vibrio parahaemolyticus 57 c3kjlF_ not modelled 6.3 36 PDB header:transcription Chain: F: PDB Molecule:saga-associated factor 11; PDBTitle: sgf11:sus1 complex 58 c3kjlH_ not modelled 5.6 36 PDB header:transcription Chain: H: PDB Molecule:saga-associated factor 11; PDBTitle: sgf11:sus1 complex 59 c3kjlE_ not modelled 5.6 36 PDB header:transcription Chain: E: PDB Molecule:saga-associated factor 11; PDBTitle: sgf11:sus1 complex 60 d2fhea1 not modelled 5.5 17 Fold:GST C-terminal domain-like Superfamily:GST C-terminal domain-like Family:Glutathione S-transferase (GST), C-terminal domain 61 c3c5yD_ not modelled 5.3 14 PDB header:isomerase Chain: D: PDB Molecule:ribose/galactose isomerase; PDBTitle: crystal structure of a putative ribose 5-phosphate isomerase2 (saro_3514) from novosphingobium aromaticivorans dsm at 1.81 a3 resolution

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0