PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2iyfA_

Fold library id	PDB Header	Molecule	Title
c2iyfA_	PDB header: transferase	Chain: A: PDB Molecule: oleandomycin glycosyltransferase;	PDBTitle: the crystal structure of macrolide glycosyltransferases: a2 blueprint for antibiotic engineering

Links to external resources
Added to library: Tue Mar 16 13:01:12 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence A H I A M F S I A A H G H V N P S L E V I R E L V A R G H R V T Y A I P P V F A D K V A A T G P R P V L Y H S T L P G P D A D P E A W G S T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
G G G T T
G G G T T S
S
T T S
G G G G
S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence L L D N V E P F L N D A I Q A L P Q L A D A Y A D D I P D L V L H D I T S Y P A R V L A R R W G V P A V S L S P N L V A W K G Y E E E V A E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
S T T
T
S S
T T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence P M W R E P R Q T E R G R A Y Y A R F E A W L K E N G I T E H P D T F A S H P P R S L V L I P K A L Q P H A D R V D E D V Y T F V G A C Q E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S T T
S
S S
S
G G G S T T G G G S
T T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence G G W Q R P A G A E K V V L V S L G S A F T Q P A F Y R E C V R A F G N L P G W H L V L Q I G T P A E L G E L P D N V E V H D W V P Q L A I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
S
T T T
T T
T T
G G G G
S
T T S S

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence L R Q A D L F V T H A G A G G S Q E G L A T A T P M I A V P Q A V D Q F G N A D M L Q G L G V A R K L A T E E A T A D L L R E T A L A L V D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S
T T
S T T S
-

. . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . . . 380 . . . .

Sequence D P E V A R R L R R I Q A E M A Q E G G T R R A A D L I E A E L P A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	A	H	I	A	M	F	S	I	A	A	H	G	H	V	N	P	S	L	E	V	I	R	E	L	V	A	R	G	H	R	V	T	Y	A	I	P	P	V	F	A	D	K	V	A	A	T	G	P	R	P	V	L	Y	H	S	T	L	P	G	P	D	A	D	P	E	A	W	G	S	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									S						G	G	G										T	T									G	G	G						T	T	S										S			T	T	S		G	G	G	G		S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	L	L	D	N	V	E	P	F	L	N	D	A	I	Q	A	L	P	Q	L	A	D	A	Y	A	D	D	I	P	D	L	V	L	H	D	I	T	S	Y	P	A	R	V	L	A	R	R	W	G	V	P	A	V	S	L	S	P	N	L	V	A	W	K	G	Y	E	E	E	V	A	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																								T	T	S			S						T	T												T								S	S					T	T					T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	P	M	W	R	E	P	R	Q	T	E	R	G	R	A	Y	Y	A	R	F	E	A	W	L	K	E	N	G	I	T	E	H	P	D	T	F	A	S	H	P	P	R	S	L	V	L	I	P	K	A	L	Q	P	H	A	D	R	V	D	E	D	V	Y	T	F	V	G	A	C	Q	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									S																	T	T			S										S	S					S		G	G	G	S	T	T	G	G	G	S		T	T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	G	G	W	Q	R	P	A	G	A	E	K	V	V	L	V	S	L	G	S	A	F	T	Q	P	A	F	Y	R	E	C	V	R	A	F	G	N	L	P	G	W	H	L	V	L	Q	I	G	T	P	A	E	L	G	E	L	P	D	N	V	E	V	H	D	W	V	P	Q	L	A	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							T	T		S								T	T	T															T	T		T	T										G	G	G	G		S			T	T					S	S
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	L	R	Q	A	D	L	F	V	T	H	A	G	A	G	G	S	Q	E	G	L	A	T	A	T	P	M	I	A	V	P	Q	A	V	D	Q	F	G	N	A	D	M	L	Q	G	L	G	V	A	R	K	L	A	T	E	E	A	T	A	D	L	L	R	E	T	A	L	A	L	V	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T		S																	T	T									S													T	T	S								-
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.
Sequence	D	P	E	V	A	R	R	L	R	R	I	Q	A	E	M	A	Q	E	G	G	T	R	R	A	A	D	L	I	E	A	E	L	P	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																														T	T	S