Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0ADG7
DateThu Jan 5 11:20:59 GMT 2012
Unique Job ID457124733e888748

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1zfjA_
Top template information
PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine monophosphate dehydrogenase;
PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes
Confidence and coverage
Confidence:100.0% Coverage: 96%
468 residues ( 96% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MLRIAKEALTFDDVLLVPAHSTVLPNTADLSTQLTKTIRLNIPMLSAAMDTVTEARLAIA
Secondary structure 
SS confidence 
Disorder  ???????
?
?
????
?
?
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  LAQEGGIGFIHKNMSIERQAEEVRRVKKHESGVVTDPQTVLPTTTLREVKELTERNGFAG
Secondary structure 
SS confidence 
Disorder 
?
?
?
???????????
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  YPVVTEENELVGIITGRDVRFVTDLNQPVSVYMTPKERLVTVREGEAREVVLAKMHEKRV
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  EKALVVDDEFHLIGMITVKDFQKAERKPNACKDEQGRLRVGAAVGAGAGNEERVDALVAA
Secondary structure 
SS confidence 
Disorder 
?????????????
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  GVDVLLIDSSHGHSEGVLQRIRETRAKYPDLQIIGGNVATAAGARALAEAGCSAVKVGIG
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  PGSICTTRIVTGVGVPQITAVADAVEALEGTGIPVIADGGIRFSGDIAKAIAAGASAVMV
Secondary structure 
SS confidence 
Disorder 
????
???
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  GSMLAGTEESPGEIELYQGRSYKSYRGMGSLGAMSKGSSDRYFQSDNAADKLVPEGIEGR
Secondary structure 
SS confidence 
Disorder 
???????????????
Disorder confidence 
 
   .........430.........440.........450.........460.........470.........480
Sequence  VAYKGRLKEIIHQQMGGLRSCMGLTGCGTIDELRTKAEFVRISGAGIQESHVHDVTITKE
Secondary structure 
SS confidence 
Disorder 
???????????
Disorder confidence 
 
   ........
Sequence  SPNYRLGS
Secondary structure 
SS confidence 
Disorder 
???????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1zfj chain A

3D model

Region: 3 - 484
Aligned: 468
Modelled: 468
Confidence: 100.0%
Identity: 55%
PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine monophosphate dehydrogenase;
PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes

Phyre2

PDB 1zfj chain A domain 1

3D model

Region: 3 - 484
Aligned: 344
Modelled: 356
Confidence: 100.0%
Identity: 60%
Fold: TIM beta/alpha-barrel
Superfamily: Inosine monophosphate dehydrogenase (IMPDH)
Family: Inosine monophosphate dehydrogenase (IMPDH)

Phyre2

PDB 1pvn chain A domain 1

3D model

Region: 4 - 478
Aligned: 343
Modelled: 348
Confidence: 100.0%
Identity: 44%
Fold: TIM beta/alpha-barrel
Superfamily: Inosine monophosphate dehydrogenase (IMPDH)
Family: Inosine monophosphate dehydrogenase (IMPDH)

Phyre2

PDB 2cu0 chain A domain 1

3D model

Region: 2 - 483
Aligned: 353
Modelled: 365
Confidence: 100.0%
Identity: 56%
Fold: TIM beta/alpha-barrel
Superfamily: Inosine monophosphate dehydrogenase (IMPDH)
Family: Inosine monophosphate dehydrogenase (IMPDH)

Phyre2

PDB 1jr1 chain A domain 1

3D model

Region: 5 - 482
Aligned: 347
Modelled: 347
Confidence: 100.0%
Identity: 45%
Fold: TIM beta/alpha-barrel
Superfamily: Inosine monophosphate dehydrogenase (IMPDH)
Family: Inosine monophosphate dehydrogenase (IMPDH)

Phyre2

PDB 2cu0 chain B

3D model

Region: 2 - 481
Aligned: 350
Modelled: 362
Confidence: 100.0%
Identity: 56%
PDB header:oxidoreductase
Chain: B: PDB Molecule:inosine-5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine-5'-monophosphate dehydrogenase from2 pyrococcus horikoshii ot3

Phyre2

PDB 1jcn chain A

3D model

Region: 5 - 468
Aligned: 374
Modelled: 378
Confidence: 100.0%
Identity: 43%
PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine monophosphate dehydrogenase i;
PDBTitle: binary complex of human type-i inosine monophosphate dehydrogenase2 with 6-cl-imp

Phyre2

PDB 3r2g chain A

3D model

Region: 7 - 467
Aligned: 320
Modelled: 331
Confidence: 100.0%
Identity: 41%
PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine 5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine 5' monophosphate dehydrogenase from2 legionella pneumophila

Phyre2

PDB 1me9 chain A

3D model

Region: 4 - 467
Aligned: 330
Modelled: 332
Confidence: 100.0%
Identity: 43%
PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine-5'-monophosphate dehydrogenase;
PDBTitle: inosine monophosphate dehydrogenase (impdh) from2 tritrichomonas foetus with imp bound

Phyre2

PDB 1eep chain A

3D model

Region: 3 - 465
Aligned: 313
Modelled: 313
Confidence: 100.0%
Identity: 60%
Fold: TIM beta/alpha-barrel
Superfamily: Inosine monophosphate dehydrogenase (IMPDH)
Family: Inosine monophosphate dehydrogenase (IMPDH)

Phyre2

PDB 2a7r chain D

3D model

Region: 7 - 463
Aligned: 301
Modelled: 301
Confidence: 100.0%
Identity: 37%
PDB header:oxidoreductase
Chain: D: PDB Molecule:gmp reductase 2;
PDBTitle: crystal structure of human guanosine monophosphate2 reductase 2 (gmpr2)

Phyre2

PDB 1vrd chain A

3D model

Region: 6 - 463
Aligned: 320
Modelled: 320
Confidence: 100.0%
Identity: 67%
PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine-5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine-5'-monophosphate dehydrogenase (tm1347)2 from thermotoga maritima at 2.18 a resolution

Phyre2

PDB 1vrd chain A domain 1

3D model

Region: 6 - 463
Aligned: 304
Modelled: 304
Confidence: 100.0%
Identity: 66%
Fold: TIM beta/alpha-barrel
Superfamily: Inosine monophosphate dehydrogenase (IMPDH)
Family: Inosine monophosphate dehydrogenase (IMPDH)

Phyre2

PDB 1jcn chain A domain 1

3D model

Region: 5 - 467
Aligned: 298
Modelled: 298
Confidence: 100.0%
Identity: 46%
Fold: TIM beta/alpha-barrel
Superfamily: Inosine monophosphate dehydrogenase (IMPDH)
Family: Inosine monophosphate dehydrogenase (IMPDH)

Phyre2

PDB 3khj chain E

3D model

Region: 2 - 465
Aligned: 297
Modelled: 297
Confidence: 100.0%
Identity: 57%
PDB header:oxidoreductase
Chain: E: PDB Molecule:inosine-5-monophosphate dehydrogenase;
PDBTitle: c. parvum inosine monophosphate dehydrogenase bound by inhibitor c64

Phyre2

PDB 2qr6 chain A

3D model

Region: 1 - 460
Aligned: 347
Modelled: 354
Confidence: 100.0%
Identity: 24%
PDB header:oxidoreductase
Chain: A: PDB Molecule:imp dehydrogenase/gmp reductase;
PDBTitle: crystal structure of imp dehydrogenase/gmp reductase-like protein2 (np_599840.1) from corynebacterium glutamicum atcc 13032 kitasato at3 1.50 a resolution

Phyre2

PDB 3ffs chain C

3D model

Region: 3 - 465
Aligned: 297
Modelled: 310
Confidence: 100.0%
Identity: 55%
PDB header:oxidoreductase
Chain: C: PDB Molecule:inosine-5-monophosphate dehydrogenase;
PDBTitle: the crystal structure of cryptosporidium parvum inosine-5'-2 monophosphate dehydrogenase

Phyre2

PDB 1ypf chain B

3D model

Region: 8 - 465
Aligned: 290
Modelled: 294
Confidence: 100.0%
Identity: 34%
PDB header:oxidoreductase
Chain: B: PDB Molecule:gmp reductase;
PDBTitle: crystal structure of guac (ba5705) from bacillus anthracis at 1.8 a2 resolution

Phyre2

PDB 2z6j chain B

3D model

Region: 30 - 443
Aligned: 272
Modelled: 289
Confidence: 100.0%
Identity: 26%
PDB header:oxidoreductase
Chain: B: PDB Molecule:trans-2-enoyl-acp reductase ii;
PDBTitle: crystal structure of s. pneumoniae enoyl-acyl carrier2 protein reductase (fabk) in complex with an inhibitor

Phyre2

PDB 3bw2 chain A

3D model

Region: 32 - 443
Aligned: 307
Modelled: 318
Confidence: 100.0%
Identity: 25%
PDB header:oxidoreductase
Chain: A: PDB Molecule:2-nitropropane dioxygenase;
PDBTitle: crystal structures and site-directed mutagenesis study of nitroalkane2 oxidase from streptomyces ansochromogenes

Phyre2
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c1zfjA_
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d1zfja1
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d1pvna1
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d2cu0a1
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d1jr1a1
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c2cu0B_
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c1jcnA_
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c3r2gA_
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c1me9A_
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d1eepa_
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c2a7rD_
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c1vrdA_
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d1vrda1
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d1jcna1
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c3khjE_
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c2qr6A_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1zfjA_
100.0 55 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine monophosphate dehydrogenase;
PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes
2d1zfja1
100.0 60 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
3d1pvna1
100.0 44 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
4d2cu0a1
100.0 56 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
5d1jr1a1
100.0 45 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
6c2cu0B_
100.0 56 PDB header:oxidoreductase
Chain: B: PDB Molecule:inosine-5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine-5'-monophosphate dehydrogenase from2 pyrococcus horikoshii ot3
7c1jcnA_
100.0 43 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine monophosphate dehydrogenase i;
PDBTitle: binary complex of human type-i inosine monophosphate dehydrogenase2 with 6-cl-imp
8c3r2gA_
100.0 41 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine 5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine 5' monophosphate dehydrogenase from2 legionella pneumophila
9c1me9A_
100.0 43 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine-5'-monophosphate dehydrogenase;
PDBTitle: inosine monophosphate dehydrogenase (impdh) from2 tritrichomonas foetus with imp bound
10d1eepa_
100.0 60 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
11c2a7rD_
100.0 37 PDB header:oxidoreductase
Chain: D: PDB Molecule:gmp reductase 2;
PDBTitle: crystal structure of human guanosine monophosphate2 reductase 2 (gmpr2)
12c1vrdA_
100.0 67 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine-5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine-5'-monophosphate dehydrogenase (tm1347)2 from thermotoga maritima at 2.18 a resolution
13d1vrda1
100.0 66 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
14d1jcna1
100.0 46 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
15c3khjE_
100.0 57 PDB header:oxidoreductase
Chain: E: PDB Molecule:inosine-5-monophosphate dehydrogenase;
PDBTitle: c. parvum inosine monophosphate dehydrogenase bound by inhibitor c64
16c2qr6A_
100.0 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:imp dehydrogenase/gmp reductase;
PDBTitle: crystal structure of imp dehydrogenase/gmp reductase-like protein2 (np_599840.1) from corynebacterium glutamicum atcc 13032 kitasato at3 1.50 a resolution
17c3ffsC_
100.0 55 PDB header:oxidoreductase
Chain: C: PDB Molecule:inosine-5-monophosphate dehydrogenase;
PDBTitle: the crystal structure of cryptosporidium parvum inosine-5'-2 monophosphate dehydrogenase
18c1ypfB_
100.0 34 PDB header:oxidoreductase
Chain: B: PDB Molecule:gmp reductase;
PDBTitle: crystal structure of guac (ba5705) from bacillus anthracis at 1.8 a2 resolution
19c2z6jB_
100.0 26 PDB header:oxidoreductase
Chain: B: PDB Molecule:trans-2-enoyl-acp reductase ii;
PDBTitle: crystal structure of s. pneumoniae enoyl-acyl carrier2 protein reductase (fabk) in complex with an inhibitor
20c3bw2A_
100.0 25 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-nitropropane dioxygenase;
PDBTitle: crystal structures and site-directed mutagenesis study of nitroalkane2 oxidase from streptomyces ansochromogenes
21c3bo9B_
not modelled 100.0 23 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative nitroalkan dioxygenase;
PDBTitle: crystal structure of putative nitroalkan dioxygenase (tm0800) from2 thermotoga maritima at 2.71 a resolution
22c2gjlA_
not modelled 100.0 29 PDB header:oxidoreductase
Chain: A: PDB Molecule:hypothetical protein pa1024;
PDBTitle: crystal structure of 2-nitropropane dioxygenase
23c2zrvC_
not modelled 99.9 24 PDB header:isomerase
Chain: C: PDB Molecule:isopentenyl-diphosphate delta-isomerase;
PDBTitle: crystal structure of sulfolobus shibatae isopentenyl2 diphosphate isomerase in complex with reduced fmn.
24c2a7nA_
not modelled 99.9 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:l(+)-mandelate dehydrogenase;
PDBTitle: crystal structure of the g81a mutant of the active chimera of (s)-2 mandelate dehydrogenase
25d1tb3a1
not modelled 99.9 25 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
26d1p0ka_
not modelled 99.9 28 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
27d1goxa_
not modelled 99.9 24 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
28c2e77B_
not modelled 99.9 26 PDB header:oxidoreductase
Chain: B: PDB Molecule:lactate oxidase;
PDBTitle: crystal structure of l-lactate oxidase with pyruvate complex
29d1p4ca_
not modelled 99.9 22 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
30d1vcfa1
not modelled 99.9 25 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
31d1kbia1
not modelled 99.9 22 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
32c1kbiB_
not modelled 99.9 23 PDB header:oxidoreductase
Chain: B: PDB Molecule:cytochrome b2;
PDBTitle: crystallographic study of the recombinant flavin-binding domain of2 baker's yeast flavocytochrome b2: comparison with the intact wild-3 type enzyme
33c2rduA_
not modelled 99.9 25 PDB header:oxidoreductase
Chain: A: PDB Molecule:hydroxyacid oxidase 1;
PDBTitle: crystal structure of human glycolate oxidase in complex with2 glyoxylate
34d1zfja4
not modelled 99.8 42 Fold:CBS-domain pair
Superfamily:CBS-domain pair
Family:CBS-domain pair
35c2qh1B_
not modelled 99.8 20 PDB header:unknown function
Chain: B: PDB Molecule:hypothetical protein ta0289;
PDBTitle: structure of ta289, a cbs-rubredoxin-like protein, in its fe+2-bound2 state
36d1vr9a3
not modelled 99.8 23 Fold:CBS-domain pair
Superfamily:CBS-domain pair
Family:CBS-domain pair
37c2ouxB_
not modelled 99.8 24 PDB header:transport protein
Chain: B: PDB Molecule:magnesium transporter;
PDBTitle: crystal structure of the soluble part of a magnesium transporter
38c3jtfB_
not modelled 99.8 15 PDB header:transport protein
Chain: B: PDB Molecule:magnesium and cobalt efflux protein;
PDBTitle: the cbs domain pair structure of a magnesium and cobalt efflux protein2 from bordetella parapertussis in complex with amp
39c2qr1E_
not modelled 99.8 17 PDB header:transferase
Chain: E: PDB Molecule:protein c1556.08c;
PDBTitle: crystal structure of the adenylate sensor from amp-activated protein2 kinase in complex with adp
40d1o50a3
not modelled 99.8 19 Fold:CBS-domain pair
Superfamily:CBS-domain pair
Family:CBS-domain pair
41d3ddja1
not modelled 99.8 27 Fold:CBS-domain pair
Superfamily:CBS-domain pair
Family:CBS-domain pair
42d1juba_
not modelled 99.8 17 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
43c1vr9B_
not modelled 99.8 23 PDB header:unknown function
Chain: B: PDB Molecule:cbs domain protein/act domain protein;
PDBTitle: crystal structure of a cbs domain pair/act domain protein (tm0892)2 from thermotoga maritima at 1.70 a resolution
44c2cdh1_
not modelled 99.8 27 PDB header:transferase
Chain: 1: PDB Molecule:enoyl reductase;
PDBTitle: architecture of the thermomyces lanuginosus fungal fatty2 acid synthase at 5 angstrom resolution.
45c3nqrD_
not modelled 99.8 18 PDB header:transport protein
Chain: D: PDB Molecule:magnesium and cobalt efflux protein corc;
PDBTitle: a putative cbs domain-containing protein from salmonella typhimurium2 lt2
46c3ocmA_
not modelled 99.8 19 PDB header:membrane protein
Chain: A: PDB Molecule:putative membrane protein;
PDBTitle: the crystal structure of a domain from a possible membrane protein of2 bordetella parapertussis
47c3fwrB_
not modelled 99.8 17 PDB header:transcription
Chain: B: PDB Molecule:yqzb protein;
PDBTitle: crystal structure of the cbs domains from the bacillus subtilis ccpn2 repressor complexed with adp
48c2v8qE_
not modelled 99.8 21 PDB header:transferase
Chain: E: PDB Molecule:5'-amp-activated protein kinase subunit gamma-1;
PDBTitle: crystal structure of the regulatory fragment of mammalian2 ampk in complexes with amp
49c2qlvF_
not modelled 99.8 19 PDB header:transferase/protein binding
Chain: F: PDB Molecule:nuclear protein snf4;
PDBTitle: crystal structure of the heterotrimer core of the s.2 cerevisiae ampk homolog snf1
50c3lhhA_
not modelled 99.8 17 PDB header:membrane protein
Chain: A: PDB Molecule:cbs domain protein;
PDBTitle: the crystal structure of cbs domain protein from shewanella2 oneidensis mr-1.
51c3i8nB_
not modelled 99.8 16 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein vp2912;
PDBTitle: a domain of a conserved functionally known protein from2 vibrio parahaemolyticus rimd 2210633.
52d2ouxa2
not modelled 99.8 24 Fold:CBS-domain pair
Superfamily:CBS-domain pair
Family:CBS-domain pair
53d2yzqa1
not modelled 99.8 25 Fold:CBS-domain pair
Superfamily:CBS-domain pair
Family:CBS-domain pair
54c3lfrB_
not modelled 99.8 19 PDB header:transport protein
Chain: B: PDB Molecule:putative metal ion transporter;
PDBTitle: the crystal structure of a cbs domain from a putative metal2 ion transporter bound to amp from pseudomonas syringae to3 1.55a
55d2d4za3
not modelled 99.8 18 Fold:CBS-domain pair
Superfamily:CBS-domain pair
Family:CBS-domain pair
56d1pvma4
not modelled 99.8 21 Fold:CBS-domain pair
Superfamily:CBS-domain pair
Family:CBS-domain pair
57c3kxrA_
not modelled 99.8 15 PDB header:transport protein
Chain: A: PDB Molecule:magnesium transporter, putative;
PDBTitle: structure of the cystathionine beta-synthase pair domain of the2 putative mg2+ transporter so5017 from shewanella oneidensis mr-1.
58d2ooxe2
not modelled 99.7 18 Fold:CBS-domain pair
Superfamily:CBS-domain pair
Family:CBS-domain pair
59c3hf7A_
not modelled 99.7 13 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized cbs-domain protein;
PDBTitle: the crystal structure of a cbs-domain pair with bound amp from2 klebsiella pneumoniae to 2.75a
60c3ocmB_
not modelled 99.7 19 PDB header:membrane protein
Chain: B: PDB Molecule:putative membrane protein;
PDBTitle: the crystal structure of a domain from a possible membrane protein of2 bordetella parapertussis
61c3fnaA_
not modelled 99.7 20 PDB header:isomerase
Chain: A: PDB Molecule:possible arabinose 5-phosphate isomerase;
PDBTitle: crystal structure of the cbs pair of possible d-arabinose 5-phosphate2 isomerase yrbh from escherichia coli cft073
62d2b4ga1
not modelled 99.7 16 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
63c2yvxD_
not modelled 99.7 26 PDB header:transport protein
Chain: D: PDB Molecule:mg2+ transporter mgte;
PDBTitle: crystal structure of magnesium transporter mgte
64c2d4zB_
not modelled 99.7 18 PDB header:transport protein
Chain: B: PDB Molecule:chloride channel protein;
PDBTitle: crystal structure of the cytoplasmic domain of the chloride channel2 clc-0
65c2yvzA_
not modelled 99.7 24 PDB header:transport protein
Chain: A: PDB Molecule:mg2+ transporter mgte;
PDBTitle: crystal structure of magnesium transporter mgte cytosolic domain,2 mg2+-free form
66c3lv9A_
not modelled 99.7 18 PDB header:membrane protein
Chain: A: PDB Molecule:putative transporter;
PDBTitle: crystal structure of cbs domain of a putative transporter from2 clostridium difficile 630
67d2nyca1
not modelled 99.7 19 Fold:CBS-domain pair
Superfamily:CBS-domain pair
Family:CBS-domain pair
68c3pc3A_
not modelled 99.7 16 PDB header:lyase
Chain: A: PDB Molecule:cg1753, isoform a;
PDBTitle: full length structure of cystathionine beta-synthase from drosophila2 in complex with aminoacrylate
69c3kpbA_
not modelled 99.7 23 PDB header:unknown function
Chain: A: PDB Molecule:uncharacterized protein mj0100;
PDBTitle: crystal structure of the cbs domain pair of protein mj01002 in complex with 5 -methylthioadenosine and s-adenosyl-l-3 methionine.
70d2yzia1
not modelled 99.7 20 Fold:CBS-domain pair
Superfamily:CBS-domain pair
Family:CBS-domain pair
71d1y5ha3
not modelled 99.7 16 Fold:CBS-domain pair
Superfamily:CBS-domain pair
Family:CBS-domain pair
72c3oi8B_
not modelled 99.7 17 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: the crystal structure of functionally unknown conserved protein domain2 from neisseria meningitidis mc58
73c3orgB_
not modelled 99.7 12 PDB header:transport protein
Chain: B: PDB Molecule:cmclc;
PDBTitle: crystal structure of a eukaryotic clc transporter
74c3gbyA_
not modelled 99.7 13 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein ct1051;
PDBTitle: crystal structure of a protein with unknown function ct10512 from chlorobium tepidum
75c2emqA_
not modelled 99.7 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical conserved protein;
PDBTitle: hypothetical conserved protein (gk1048) from geobacillus kaustophilus
76d2ef7a1
not modelled 99.7 25 Fold:CBS-domain pair
Superfamily:CBS-domain pair
Family:CBS-domain pair
77d2v8qe1
not modelled 99.7 19 Fold:CBS-domain pair
Superfamily:CBS-domain pair
Family:CBS-domain pair
78c2p9mD_
not modelled 99.7 18 PDB header:structural genomics, unknown function
Chain: D: PDB Molecule:hypothetical protein mj0922;
PDBTitle: crystal structure of conserved hypothetical protein mj0922 from2 methanocaldococcus jannaschii dsm 2661
79c3ocoB_
not modelled 99.7 22 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:hemolysin-like protein containing cbs domains;
PDBTitle: the crystal structure of a hemolysin-like protein containing cbs2 domain of oenococcus oeni psu
80c3oixA_
not modelled 99.7 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative dihydroorotate dehydrogenase; dihydroorotate
PDBTitle: crystal structure of the putative dihydroorotate dehydrogenase from2 streptococcus mutans
81d1pbja3
not modelled 99.7 30 Fold:CBS-domain pair
Superfamily:CBS-domain pair
Family:CBS-domain pair
82d2ooxe1
not modelled 99.7 15 Fold:CBS-domain pair
Superfamily:CBS-domain pair
Family:CBS-domain pair
83d3ddja2
not modelled 99.7 17 Fold:CBS-domain pair
Superfamily:CBS-domain pair
Family:CBS-domain pair
84d2j9la1
not modelled 99.7 26 Fold:CBS-domain pair
Superfamily:CBS-domain pair
Family:CBS-domain pair
85d2riha1
not modelled 99.7 19 Fold:CBS-domain pair
Superfamily:CBS-domain pair
Family:CBS-domain pair
86d2v8qe2
not modelled 99.7 11 Fold:CBS-domain pair
Superfamily:CBS-domain pair
Family:CBS-domain pair
87c3lqnA_
not modelled 99.7 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:cbs domain protein;
PDBTitle: crystal structure of cbs domain-containing protein of2 unknown function from bacillus anthracis str. ames ancestor
88d1yava3
not modelled 99.7 14 Fold:CBS-domain pair
Superfamily:CBS-domain pair
Family:CBS-domain pair
89d2o16a3
not modelled 99.7 26 Fold:CBS-domain pair
Superfamily:CBS-domain pair
Family:CBS-domain pair
90c1yavB_
not modelled 99.7 15 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:hypothetical protein bsu14130;
PDBTitle: crystal structure of cbs domain-containing protein ykul2 from bacillus subtilis
91c3ctuB_
not modelled 99.7 24 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:cbs domain protein;
PDBTitle: crystal structure of cbs domain protein from streptococcus2 pneumoniae tigr4
92c3fhmD_
not modelled 99.7 23 PDB header:structural genomics, unknown function, n
Chain: D: PDB Molecule:uncharacterized protein atu1752;
PDBTitle: crystal structure of the cbs-domain containing protein atu1752 from2 agrobacterium tumefaciens
93d2rc3a1
not modelled 99.7 21 Fold:CBS-domain pair
Superfamily:CBS-domain pair
Family:CBS-domain pair
94d1yxya1
not modelled 99.6 19 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
95c3l31B_
not modelled 99.6 30 PDB header:hydrolase
Chain: B: PDB Molecule:probable manganase-dependent inorganic
PDBTitle: crystal structure of the cbs and drtgg domains of the2 regulatory region of clostridium perfringens3 pyrophosphatase complexed with the inhibitor, amp
96c2pfiA_
not modelled 99.6 15 PDB header:transport protein
Chain: A: PDB Molecule:chloride channel protein clc-ka;
PDBTitle: crystal structure of the cytoplasmic domain of the human2 chloride channel clc-ka
97c3kh5A_
not modelled 99.6 38 PDB header:unknown function
Chain: A: PDB Molecule:protein mj1225;
PDBTitle: crystal structure of protein mj1225 from methanocaldococcus2 jannaschii, a putative archaeal homolog of g-ampk.
98d1gtea2
not modelled 99.6 21 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
99c3gyeA_
not modelled 99.6 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydroorotate dehydrogenase, putative;
PDBTitle: didydroorotate dehydrogenase from leishmania major
100d1y0ea_
not modelled 99.6 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
101c3igsB_
not modelled 99.6 19 PDB header:isomerase
Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2;
PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase
102d2yvxa2
not modelled 99.6 23 Fold:CBS-domain pair
Superfamily:CBS-domain pair
Family:CBS-domain pair
103c3q58A_
not modelled 99.6 19 PDB header:isomerase
Chain: A: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase;
PDBTitle: structure of n-acetylmannosamine-6-phosphate epimerase from salmonella2 enterica
104c3ddjA_
not modelled 99.6 25 PDB header:amp-binding protein
Chain: A: PDB Molecule:cbs domain-containing protein;
PDBTitle: crystal structure of a cbs domain-containing protein in complex with2 amp (sso3205) from sulfolobus solfataricus at 1.80 a resolution
105c2yzqA_
not modelled 99.6 25 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative uncharacterized protein ph1780;
PDBTitle: crystal structure of uncharacterized conserved protein from2 pyrococcus horikoshii
106d1ep3a_
not modelled 99.6 20 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
107d1d3ga_
not modelled 99.6 18 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
108d1uuma_
not modelled 99.6 20 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
109d2yzqa2
not modelled 99.5 27 Fold:CBS-domain pair
Superfamily:CBS-domain pair
Family:CBS-domain pair
110c2fptA_
not modelled 99.5 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydroorotate dehydrogenase, mitochondrial;
PDBTitle: dual binding mode of a novel series of dhodh inhibitors
111d1ea0a2
not modelled 99.5 17 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
112d1ofda2
not modelled 99.5 19 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
113c2htmB_
not modelled 99.5 20 PDB header:biosynthetic protein
Chain: B: PDB Molecule:thiazole biosynthesis protein thig;
PDBTitle: crystal structure of ttha0676 from thermus thermophilus hb8
114c2w6rA_
not modelled 99.5 24 PDB header:lyase
Chain: A: PDB Molecule:imidazole glycerol phosphate synthase subunit
PDBTitle: crystal structure of an artificial (ba)8-barrel protein2 designed from identical half barrels
115c1tv5A_
not modelled 99.4 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydroorotate dehydrogenase homolog, mitochondrial;
PDBTitle: plasmodium falciparum dihydroorotate dehydrogenase with a bound2 inhibitor
116d1tv5a1
not modelled 99.4 18 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
117c3qjaA_
not modelled 99.4 18 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form
118d1thfd_
not modelled 99.4 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
119d1h5ya_
not modelled 99.4 21 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
120d1f76a_
not modelled 99.4 17 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0